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https://www.readbyqxmd.com/read/29470939/free-breathing-pulmonary-mr-imaging-to-quantify-regional-ventilation
#1
Dante P I Capaldi, Rachel L Eddy, Sarah Svenningsen, Fumin Guo, John S H Baxter, A Jonathan McLeod, Parameswaran Nair, David G McCormack, Grace Parraga
Purpose To measure regional specific ventilation with free-breathing hydrogen 1 (1 H) magnetic resonance (MR) imaging without exogenous contrast material and to investigate correlations with hyperpolarized helium 3 (3 He) MR imaging and pulmonary function test measurements in healthy volunteers and patients with asthma. Materials and Methods Subjects underwent free-breathing1 H and static breath-hold hyperpolarized3 He MR imaging as well as spirometry and plethysmography; participants were consecutively recruited between January and June 2017...
February 22, 2018: Radiology
https://www.readbyqxmd.com/read/29470640/quantitative-susceptibility-mapping-in-combination-with-water-fat-separation-for-simultaneous-liver-iron-and-fat-fraction-quantification
#2
Huimin Lin, Hongjiang Wei, Naying He, Caixia Fu, Shu Cheng, Jun Shen, Baisong Wang, Xu Yan, Chunlei Liu, Fuhua Yan
PURPOSES: To evaluate the feasibility of simultaneous quantification of liver iron concentration (LIC) and fat fraction (FF) using water-fat separation and quantitative susceptibility mapping (QSM). METHODS: Forty-five patients suspected of liver iron overload (LIO) were included. A volumetric interpolated breath-hold examination sequence for QSM and FF, a fat-saturated gradient echo sequence for R2 * , a spin echo sequence for LIC measurements and MRS analyses for FF (FF-MRS) were performed...
February 22, 2018: European Radiology
https://www.readbyqxmd.com/read/29470624/measuring-liver-t2-and-cardiac-t2-in-a-single-acquisition
#3
Suraj D Serai, Andrew T Trout, Robert J Fleck, Charles T Quinn, Jonathan R Dillman
PURPOSE: The purpose of this study is determine if both liver T2* and cardiac T2* can be measured on a single breath-hold acquisition. MATERIALS AND METHODS: For this IRB-approved retrospective study, 137 patients with dedicated Cardiac MRI and Liver MRI examinations obtained sequentially on 1.5T scanners and on the same day were included for analysis. Both the cardiac and liver MRI examinations utilized GRE sequences for quantification of tissue iron. Specifically, T2* was measured using an 8-echo, multi-echo gradient echo single breath-hold sequence...
February 22, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29470150/metrics-of-lung-tissue-heterogeneity-depend-on-bmi-but-not-age
#4
Karthik Subramaniam, Alys R Clark, Eric A Hoffman, Merryn H Tawhai
Altered parenchymal microstructure and complexity have been observed in older age. How to distinguish between healthy, expected changes and early signs of pathology remains poorly understood. An objective quantitative analysis of computed tomography (CT) imaging was conducted to compare mean lung density (MLD), tissue density distributions, and tissue heterogeneity in 16 subjects - 8 aged >60 years who were gender- and BMI-matched with 8 subjects aged <30 years. Subjects were never-smoking, with no prior respiratory disease, and no radiologically-identified abnormalities on CT...
February 22, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29468535/methodological-implications-and-repeatability-of-nasal-nitric-oxide-relevance-for-challenge-studies
#5
Frank Hoffmeyer, K Sucker, H Berresheim, C Monsé, B Jettkant, A Beine, M Raulf, T Brüning, J Bünger
There is an interest in assessing changes in nasal NO (nNO) levels as an effect marker of upper airways. In this study, we examined methodologic influences on short and long term repeatability of nNO levels assessed by a portable electrochemical analyzer. Nine atopic and eighteen healthy subjects were exposed for 4 h to ethyl acrylate concentration of 0.05 ppm (sham) and mean concentrations of 5 ppm (either constant 5 ppm or variable 0 to 10 ppm). Sampling of nNO was performed by using passive aspiration during both breath-holding (634 ppb) or calm tidal breathing (364 ppb, p < 0...
February 22, 2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29463958/interfractional-diaphragm-changes-during-breath-holding-in-stereotactic-body-radiotherapy-for-liver-cancer
#6
Daisuke Kawahara, Shuichi Ozawa, Takeo Nakashima, Shintaro Tsuda, Yusuke Ochi, Takuro Okumura, Hirokazu Masuda, Kazunari Hioki, Tathsuhiko Suzuki, Yoshimi Ohno, Tomoki Kimura, Yuji Murakami, Yasushi Nagata
Aim and background: IGRT based on bone matching may produce a large target positioning error in terms of the reproducibility of expiration breath-holding on SBRT for liver cancer. We evaluated the intrafractional and interfractional errors using the diaphragm position at the end of expiration by utilising Abches and analysed the factor of the interfractional error. Materials and methods: Intrafractional and interfractional errors were measured using a couple of frontal kV images, planning computed tomography (pCT) and daily cone-beam computed tomography (CBCT)...
March 2018: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/29459539/-optimization-of-scan-parameters-for-patient-without-breath-hold-in-chest-by-computed-tomography
#7
Hiroshi Takaku, Takeshi Sakamoto, Yuya Shirakawa, Takuya Adachi, Hisashi Kayama, Masakatsu Takahashi, Hiromi Ichikawa
This study aims to establish optimal scan parameters by high temporal resolution computed tomography (CT) scan for emergency patients who cannot hold their breath. First, we investigated scan parameters that can reduce the effect of motion by evaluating motion artifacts from the moving phantom scan and the temporal sensitivity profile (TPS) measurement. Second, we confirmed the standard deviation (SD) of the CT values as well as the operating time and exposure dose. As the results, plan C [rotation time: 0...
2018: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/29458927/the-effect-of-pleasant-olfactory-mental-imagery-on-the-incidence-and-extent-of-atelectasis-in-patients-after-open-heart-surgery
#8
Masoud Rezaei-Nodehi, Seyed Afshin Shorofi, Masoumeh Bagheri-Nesami, Rahman Ghafari, Jamshid Yazdani-Charati, Manizheh Darbeheshti
BACKGROUND AND PURPOSE: Atelectasis is the most common pulmonary complication after open heart surgery. This study was intended to examine the effects of pleasant olfactory mental imagery on postoperative atelectasis in patients undergoing open heart surgery. MATERIALS AND METHODS: This is a randomized controlled clinical trial. The sample consisted of 80 patients who were randomly assigned to either practice olfactory mental imagery (test group) or receive routine care (control group)...
February 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29458430/comparison-of-fast-multi-slice-and-standard-segmented-techniques-for-detection-of-late-gadolinium-enhancement-in-ischemic-and-non-ischemic-cardiomyopathy-a-prospective-clinical-cardiovascular-magnetic-resonance-trial
#9
Fabian Muehlberg, Kristin Arnhold, Simone Fritschi, Stephanie Funk, Marcel Prothmann, Josephine Kermer, Leonora Zange, Florian von Knobelsdorff-Brenkenhoff, Jeanette Schulz-Menger
BACKGROUND: Segmented phase-sensitive inversion recovery (PSIR) cardiovascular magnetic resonance (CMR) sequences are reference standard for non-invasive evaluation of myocardial fibrosis using late gadolinium enhancement (LGE). Several multi-slice LGE sequences have been introduced for faster acquisition in patients with arrhythmia and insufficient breathhold capability. The aim of this study was to assess the accuracy of several multi-slice LGE sequences to detect and quantify myocardial fibrosis in patients with ischemic and non-ischemic myocardial disease...
February 19, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29458384/cardiovascular-cine-imaging-and-flow-evaluation-using-fast-interrupted-steady-state-fiss-magnetic-resonance
#10
Robert R Edelman, Ali Serhal, Amit Pursnani, Jianing Pang, Ioannis Koktzoglou
BACKGROUND: Existing cine imaging techniques rely on balanced steady-state free precession (bSSFP) or spoiled gradient-echo readouts, each of which has limitations. For instance, with bSSFP, artifacts occur from rapid through-plane flow and off-resonance effects. We hypothesized that a prototype cine technique, radial fast interrupted steady-state (FISS), could overcome these limitations. The technique was compared with standard cine bSSFP for cardiac function, coronary artery conspicuity, and aortic valve morphology...
February 19, 2018: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29457316/assessment-of-pulmonary-structure-function-relationships-in-young-children-and-adolescents-with-cystic-fibrosis-by-multivolume-proton-mri-and-ct
#11
Francesca Pennati, David J Roach, John P Clancy, Alan S Brody, Robert J Fleck, Andrea Aliverti, Jason C Woods
BACKGROUND: Lung disease is the most frequent cause of morbidity and mortality in patients with cystic fibrosis (CF), and there is a shortage of sensitive biomarkers able to regionally monitor disease progression and to assess early responses to therapy. PURPOSE: To determine the feasibility of noncontrast-enhanced multivolume MRI, which assesses intensity changes between expiratory and inspiratory breath-hold images, to detect and quantify regional ventilation abnormalities in CF lung disease, with a focus on the structure-function relationship...
February 19, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29456518/environmental-physiology-and-diving-medicine
#12
REVIEW
Gerardo Bosco, Alex Rizzato, Richard E Moon, Enrico M Camporesi
Man's experience and exploration of the underwater environment has been recorded from ancient times and today encompasses large sections of the population for sport enjoyment, recreational and commercial purpose, as well as military strategic goals. Knowledge, respect and maintenance of the underwater world is an essential development for our future and the knowledge acquired over the last few dozen years will change rapidly in the near future with plans to establish secure habitats with specific long-term goals of exploration, maintenance and survival...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29452984/quantitative-cerebrovascular-pathology-in-a-community-based-cohort-of-older-adults
#13
Swati Rane, Natalie Koh, Peter Boord, Tara Madhyastha, Mary K Askren, Suman Jayadev, Brenna Cholerton, Eric Larson, Thomas J Grabowski
Cerebrovascular disease, especially small vessel pathology, is the leading comorbidity in degenerative disorders. We applied arterial spin labeling and cerebrovascular reserve (CVR) imaging to quantify small vessel disease and study its effect on cognitive symptoms in nondemented older adults from a community-based cohort. We evaluated baseline cerebral blood flow (CBF) using arterial spin labeling and percent signal change as a marker of CVR using blood-oxygen level-dependent imaging following a breath-hold stimulus...
January 31, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29452867/deep-inspiration-breath-hold-level-variability-and-deformation-in-locoregional-breast-irradiation
#14
Leigh Conroy, Sarah Quirk, Elizabeth Watt, Gillian Ecclestone, Jessica L Conway, Ivo A Olivotto, Tien Phan, Wendy L Smith
PURPOSE: The purpose of this study was to evaluate the dosimetric effect of breath hold level variability and deformation on breast, chest wall, internal mammary chain (IMC) nodes, and heart. METHODS AND MATERIALS: Left-sided post-lumpectomy (n = 12) and postmastectomy (n = 3) patients underwent deep inspiration breath hold (DIBH) and exhale breath hold (EBH) computed tomography (CT) scans. Forward-planned locoregional breast plans were created on the DIBH scan...
February 13, 2018: Practical Radiation Oncology
https://www.readbyqxmd.com/read/29450611/high-spatial-resolution-navigated-3d-t1-weighted-hepatobiliary-mr-cholangiography-using-gd-eob-dtpa-for-evaluation-of-biliary-anatomy-in-living-liver-donors
#15
Jei Hee Lee, Bohyun Kim, Hye Jin Kim, Bong-Wan Kim, Hee-Jung Wang, Jai Keun Kim
PURPOSE: To determine the feasibility of high-resolution navigated three-dimensional (3D) T1-weighted hepatobiliary MR cholangiography (Nav T1 MRC) using Gd-EOB-DTPA for biliary visualization in living liver donors and to assess added value of 3D T1-weighted hepatobiliary MRCs in improving the confidence and diagnostic accuracy of biliary anatomy in complementary to T2-weighted MRCs. METHODS: Twenty-nine right liver donors underwent 3D T2 MRC, 2D T2 MRC, breath-hold T1-weighted hepatobiliary MRC (BH T1 MRC), and Nav T1 MRC...
February 15, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29446683/three-dimensional-radial-vibe-sequence-for-contrast-enhanced-brain-imaging-an-alternative-for-reducing-motion-artifacts-in-restless-children
#16
Ji Eun Park, Young Hun Choi, Jung-Eun Cheon, Woo Sun Kim, In-One Kim, Young Jin Ryu, MunYoung Paek
OBJECTIVE: The purpose of this study was to evaluate the usefulness of radially sampled 3D fat-suppressed T1-weighted gradient-echo sequences (radial volumetric interpolated breath-hold examination [radial VIBE]) for contrast-enhanced brain MRI of children through comparison with a magnetization-prepared rapid-acquisition gradient-echo (MP-RAGE) sequence. MATERIALS AND METHODS: Sixty-five consecutive contrast-enhanced brain MRI examinations performed with axial MP-RAGE and radial VIBE sequences were included...
February 15, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29436168/feasibility-study-of-individualized-optimal-positioning-selection-for-left-sided-whole-breast-radiotherapy-dibh-or-prone
#17
Hui Lin, Tianyu Liu, Chengyu Shi, Saskia Petillion, Isabelle Kindts, Caroline Weltens, Tom Depuydt, Yulin Song, Ziad Saleh, Xie George Xu, Xiaoli Tang
The deep inspiration breath hold (DIBH) and prone (P) position are two common heart-sparing techniques for external-beam radiation treatment of left-sided breast cancer patients. Clinicians select the position that is deemed to be better for tissue sparing based on their experience. This approach, however, is not always optimum and consistent. In response to this, we develop a quantitative tool that predicts the optimal positioning for the sake of organs at risk (OAR) sparing. Sixteen left-sided breast cancer patients were considered in the study, each received CT scans in the supine free breathing, supine DIBH, and prone positions...
February 13, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29435300/computed-tomography-guided-lung-biopsy-association-between-biopsy-needle-angle-and-pneumothorax-development
#18
Takumi Kuriyama, Katsuhiro Masago, Yuki Okada, Nobuyuki Katakami
Computed tomography (CT)-guided lung biopsy is a well-established diagnostic method for pulmonary lesions. However, the use of this technique often results in pneumothorax development. The aim of the present study was to evaluate the association between biopsy needle angle and pneumothorax development associated with computed tomography-guided lung biopsy. We retrospectively analyzed the results of CT-guided lung biopsies for 325 cases to investigate physical risk factors for pneumothorax development. Biopsy needle angle and patient positioning were included in the analysis...
February 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29432609/impaired-cerebral-hemodynamics-and-frailty-in-patients-with-cardiovascular-disease
#19
Miri Lutski, Salo Haratz, Galit Weinstein, Uri Goldbourt, David Tanne
Background: Recent studies suggest that impaired cerebrovascular reactivity (CVR), a marker of cerebral microvascular damage, is associated with a higher risk of stroke, cognitive decline and mortality. We tested whether abnormal cerebrovascular status is associated with late-life frailty among men with pre-existing cardiovascular disease. Methods: A subset of 327 men (mean age at baseline 56.7±6.5 years) who previously participated in the Bezafibrate Infarction Prevention (BIP) trial (1990-1997) and then in the BIP Neurocognitive study underwent a neurovascular evaluation 14...
February 8, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29429610/automated-ultrafast-kilovoltage-megavoltage-cone-beam-ct-for-image-guided-radiotherapy-of-lung-cancer-system-description-and-real-time-results
#20
Manuel Blessing, Anna Arns, Hansjoerg Wertz, Dzmitry Stsepankou, Judit Boda-Heggemann, Juergen Hesser, Frederik Wenz, Frank Lohr
PURPOSE: To establish a fully automated kV-MV CBCT imaging method on a clinical linear accelerator that allows image acquisition of thoracic targets for patient positioning within one breath-hold (∼15s) under realistic clinical conditions. METHODS AND MATERIALS: Our previously developed FPGA-based hardware unit which allows synchronized kV-MV CBCT projection acquisition is connected to a clinical linear accelerator system via a multi-pin switch; i.e. either kV-MV imaging or conventional clinical mode can be selected...
February 8, 2018: Zeitschrift Für Medizinische Physik
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