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Remineralization

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https://www.readbyqxmd.com/read/28812312/a-systematic-review-of-silver-diamine-fluoride-effectiveness-and-application-in-older-adults
#1
REVIEW
Amruta D Hendre, George W Taylor, Elisa M Chávez, Susan Hyde
OBJECTIVE: This systematic review examines the effectiveness of silver diamine fluoride (SDF) in the management of caries in older adults. BACKGROUND: Silver diamine fluoride has been extensively researched and proven effective for caries prevention and arrest in children. Limited studies support its effectiveness in adult and older adult populations. MATERIALS AND METHODS: Multiple databases were searched according to specified inclusion-exclusion criteria...
August 15, 2017: Gerodontology
https://www.readbyqxmd.com/read/28782284/factors-affecting-the-bacterial-community-composition-and-heterotrophic-production-of-columbia-river-estuarine-turbidity-maxima
#2
Lydie Herfort, Byron C Crump, Caroline S Fortunato, Lee Ann McCue, Victoria Campbell, Holly M Simon, António M Baptista, Peter Zuber
Estuarine turbidity maxima (ETM) function as hotspots of microbial activity and diversity in estuaries, yet, little is known about the temporal and spatial variability in ETM bacterial community composition. To determine which environmental factors affect ETM bacterial populations in the Columbia River estuary, we analyzed ETM bacterial community composition (Sanger sequencing and amplicon pyrosequencing of 16S rRNA gene) and bulk heterotrophic production ((3) H-leucine incorporation rates). We collected water 20 times to cover five ETM events and obtained 42 samples characterized by different salinities, turbidities, seasons, coastal regimes (upwelling vs...
August 6, 2017: MicrobiologyOpen
https://www.readbyqxmd.com/read/28774431/rapid-biomimetic-remineralization-of-the-demineralized-enamel-surface-using-nano-particles-of-amorphous-calcium-phosphate-guided-by-chimaeric-peptides
#3
Zuohui Xiao, Kehua Que, Haorong Wang, Ran An, Zhen Chen, Zhongjun Qiu, Mingli Lin, Jinhua Song, Jie Yang, Danyang Lu, Minjuan Shen, Binbin Guan, Yinghui Wang, Xuliang Deng, Xiaoping Yang, Qing Cai, Jiaying Deng, Li Ma, Xi Zhang, Xu Zhang
OBJECTIVE: The objective of this study was to develop a rapid and effective method to remineralize human carious-like enamel using chimaeric peptide-mediated nanocomplexes of carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP), mimicking the mineralizing pattern of the oriented assembly of ACP guided by amelogenin in the biomineralization of enamel. METHODS: CMC/ACP nanocomplex solution was first synthesized through the successive addition of carboxymethyl chitosan, calcium chloride, and dipotassium phosphate into distilled water...
July 31, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28772744/effect-and-stability-of-poly-amido-amine-induced-biomineralization-on-dentinal-tubule-occlusion
#4
Yuan Gao, Kunneng Liang, Jianshu Li, He Yuan, Hongling Liu, Xiaolei Duan, Jiyao Li
In recent years, scientists have developed various biomaterials to remineralize human teeth to treat dentine hypersensitivity. Poly(amido amine) (PAMAM) dendrimers have become a research focus in this field. It has been demonstrated that PAMAM is able to create precipitates both on the surface of and within the dentinal tubules, however, there is little information about its effect on reducing dentine permeability in vitro. This study aimed to evaluate the in vitro effectiveness and stability of the fourth generation amine-terminated PAMAM on dentinal tubule occlusion, especially on dentine permeability...
April 5, 2017: Materials
https://www.readbyqxmd.com/read/28772594/in-vitro-evaluation-of-dentin-tubule-occlusion-for-novel-calcium-lactate-phosphate-clp-paste
#5
Jen-Chang Yang, Hsin-Tai Hu, Sheng-Yang Lee, Sung-Chih Hsieh, Pei-Chi Huang, Chen-Feng Ma, Dian-Yu Ji, Liang-Yu Chang, Nai-Chia Teng
INTRODUCTION: The objective of this in vitro study is to evaluate the effective and long-term occlusion of dentinal tubules using a novel calcium lactate phosphate (CLP) based desensitizing agent. METHODS: Dentin disks (n = 9) were pre-etched using 1 M lactic acid for 30 s and individually treated with Colgate(®) Pro-Relief™ paste, CLP paste, and double distilled water (ddH₂O) by a rubber-cupped handpiece. Dentin disks were analyzed under optical micrographs for pre-treatment, directly after treatment, and 14 days post-treatment...
February 27, 2017: Materials
https://www.readbyqxmd.com/read/28772450/combining-bioactive-multifunctional-dental-composite-with-pamam-for-root-dentin-remineralization
#6
Shimeng Xiao, Kunneng Liang, Michael D Weir, Lei Cheng, Huaibing Liu, Xuedong Zhou, Yi Ding, Hockin H K Xu
Objectives. The objectives of this study were to: (1) develop a bioactive multifunctional composite (BMC) via nanoparticles of amorphous calcium phosphate (NACP), 2-methacryloyloxyethyl phosphorylcholine (MPC), dimethylaminohexadecyl methacrylate (DMAHDM) and nanoparticles of silver (NAg); and (2) investigate the effects of combined BMC + poly (amido amine) (PAMAM) on remineralization of demineralized root dentin in a cyclic artificial saliva/lactic acid environment for the first time. Methods. Root dentin specimens were prepared and demineralized with 37% phosphoric acid for 15 s...
January 22, 2017: Materials
https://www.readbyqxmd.com/read/28772391/novel-dental-adhesive-with-biofilm-regulating-and-remineralization-capabilities
#7
Yang Ge, Biao Ren, Xuedong Zhou, Hockin H K Xu, Suping Wang, Mingyun Li, Michael D Weir, Mingye Feng, Lei Cheng
The mechanical properties and anti-caries effect of a novel anti-caries adhesive containing poly (amidoamine) dendrimer (PAMAM) and dimethylaminododecyl methacrylate (DMADDM) were investigated for the first time. Microtensile bond strength and surface charge density were measured for the novel anti-caries adhesives. Streptococcus mutans, Streptococcus sanguinis, and Streptococcus gordonii were chosen to form three-species biofilms. Lactic acid assay, MTT (3-(4,5-Dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay, exopolysaccharide staining and live/dead staining were performed to study anti-biofilm effect of the adhesive...
January 3, 2017: Materials
https://www.readbyqxmd.com/read/28772386/influence-of-porous-spherical-shaped-hydroxyapatite-on-mechanical-strength-and-bioactive-function-of-conventional-glass-ionomer-cement
#8
Szu-Yu Chiu, Yukari Shinonaga, Yoko Abe, Kyoko Harada, Kenji Arita
Glass-ionomer-cement (GIC) is helpful in Minimal Intervention Dentistry because it releases fluoride ions and is highly biocompatible. The aim of this study is to investigate the mechanisms by which hydroxyapatite (HAp) improves the mechanical strength and bioactive functioning of GIC when these materials are combined to make apatite ionomer cement (AIC). A conventional GIC powder was mixed with porous, spherical-HAp particles (HApS), crystalline HAp (HAp200) or one of two types of cellulose. The micro-compressive strengths of the additive particles were measured, and various specimens were evaluated with regard to their compressive strengths (CS), fluoride release concentrations (fluoride electrode) and multi-element release concentrations...
January 3, 2017: Materials
https://www.readbyqxmd.com/read/28772269/effects-of-self-assembling-peptide-p11-4-fluorides-and-caries-infiltration-on-artificial-enamel-caries-lesions-in-vitro
#9
Richard J Wierichs, Julian Kogel, Julian Lausch, Marcella Esteves-Oliveira, Hendrik Meyer-Lueckel
The application of a self-assembling peptide on noncavitated caries lesions is supposed to be a feasible approach to facilitate remineralization and mask their unfavorable appearance. However, demineralizing conditions are common in the oral environment, so the aim of this pH-cycling study was to compare recommended and novel treatment methods regarding their ability to hamper demineralization and as a consequence mask artificial enamel caries lesions. Artificial caries lesions were prepared in bovine enamel and randomly allocated to 11 groups (n = 22)...
August 4, 2017: Caries Research
https://www.readbyqxmd.com/read/28762349/a-comparative-evaluation-of-the-remineralization-potential-of-three-commercially-available-remineralizing-agents-on-white-spot-lesions-in-primary-teeth-an-in-vitro-study
#10
Pujan Kamath, Rashmi Nayak, Shobha U Kamath, Deepika Pai
BACKGROUND: The focus in caries management has shifted to early detection of caries lesions and targeted noninvasive management of incipient lesions using novel remineralizing agents. AIM: This study aimed to compare and evaluate the remineralization potential of commercially available agents containing nano-hydroxyapatite (nano-HA), casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF), and Tricalcium phosphate (TCP) on artificially induced white spot lesions in primary teeth...
July 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28761941/effects-of-different-concentrations-and-excipients-of-titanium-tetrafluoride-on-dentin-erosion-prevention
#11
Taís Mantilla, Thayanne Ramos-Oliveira, Camila Silva, Maria Cersosimo, Cecilia Turssi, Patricia Freitas
PURPOSE: To evaluate the preventive effect of titanium fluoride (TiF4) gel and solution, in different concentrations, on dentin erosion. MATERIALS AND METHODS: Of 140 root dentin slabs (3 x 3 x 1 mm) cut from 70 freshly extracted human third molars, 70 with intermediate Knoop microhardness and lowest surface curvature were selected and randomly divided into 7 groups (n = 10): G1: negative control (no treatment); G2: positive control (AmF/NaF/SnCl2 solution); G3: placebo gel (no fluoride); G4: 1% TiF4 solution; G5: 1% TiF4 gel; G6: 4% TiF4 solution; G7: 4% TiF4 gel...
July 31, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28747477/oyster-reefs-as-carbon-sources-and-sinks
#12
F Joel Fodrie, Antonio B Rodriguez, Rachel K Gittman, Jonathan H Grabowski, Niels L Lindquist, Charles H Peterson, Michael F Piehler, Justin T Ridge
Carbon burial is increasingly valued as a service provided by threatened vegetated coastal habitats. Similarly, shellfish reefs contain significant pools of carbon and are globally endangered, yet considerable uncertainty remains regarding shellfish reefs' role as sources (+) or sinks (-) of atmospheric CO2 While CO2 release is a by-product of carbonate shell production (then burial), shellfish also facilitate atmospheric-CO2 drawdown via filtration and rapid biodeposition of carbon-fixing primary producers...
July 26, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28734567/effect-of-calcium-phosphate-nanocomposite-on-in-vitro-remineralization-of-human-dentin-lesions
#13
Michael D Weir, Jianping Ruan, Ning Zhang, Laurence C Chow, Ke Zhang, Xiaofeng Chang, Yuxing Bai, Hockin H K Xu
OBJECTIVE: Secondary caries is a primary reason for dental restoration failures. The objective of this study was to investigate the remineralization of human dentin lesions in vitro via restorations using nanocomposites containing nanoparticles of amorphous calcium phosphate (NACP) or NACP and tetracalcium phosphate (TTCP) for the first time. METHODS: NACP was synthesized by a spray-drying technique and incorporated into a resin consisting of ethoxylated bisphenol A dimethacrylate (EBPADMA) and pyromellitic glycerol dimethacrylate (PMGDM)...
July 19, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28727319/novel-evaluation-and-treatment-techniques-for-white-spot-lesions-an-in-vitro-study
#14
T A Bakhsh, A S Bakry, M M Mandurah, M A Abbassy
OBJECTIVE: White spot lesions (WSLs) are commonly seen during and after orthodontic treatment. Therefore, the objective of this in vitro study was to assess the effect of 45S5-bioglass in remineralizing WSLs using cross-polarization optical coherence tomography (CP-OCT) and confirm the findings by micro-hardness test. METHODS: Ceramic orthodontic brackets were bonded to the buccal surface of 45 human premolars with Transbond XT primer followed by Transbond PLUS according to the manufacturer's instructions...
August 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28713645/effects-of-a-novel-disc-formulation-on-dry-mouth-symptoms-and-enamel-remineralization-in-patients-with-hyposalivation-an-in-vivo-study
#15
Jessica Ho, Miracle Vania Firmalino, Afarin Golabgir Anbarani, Thair Takesh, Joel Epstein, Petra Wilder-Smith
BACKGROUND: The goal of this study was to identify the in vivo effects in patients with hyposalivation of a novel slowly dissolving adhering test disc upon on enamel remineralization, oral biofilm, salivary production, pH and buffering, gingival health, and on self-evaluation of oral well-being. METHODS: Five subjects with xerostomia wore custom made retainers carrying 5 demineralized enamel chips for periods of 1 week each. In 1 study arm, subjects used the test agent plus oral hygiene self-care; in the other they used oral hygiene self-care only, with a 1 week washout in between arms...
February 2017: Dentistry: Current Research
https://www.readbyqxmd.com/read/28713112/effect-of-casein-phosphopeptide-amorphous-calcium-phosphate-and-three-calcium-phosphate-on-enamel-microhardness
#16
En Hr Haghgou, Roza Haghgoo, Mohamad R Roholahi, Zahra Ghorbani
AIM: This study aims to investigate the effect of casein phos-phopeptide-amorphous calcium phosphate and three calcium phosphate (CPP-ACP and TCP) on increasing the microhardness of human enamel after induction of erosion. MATERIALS AND METHODS: A total of 26 healthy human-impacted third molar teeth were chosen, and their hardness measured using a microhardness testing machine. The samples were immersed in Coca Cola (pH = 4.7) for 8 minutes. Then, micro-hardness was measured again, and these samples were randomly divided into four groups (two control groups and two experimental groups)...
July 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28701639/synthesized-mesoporous-silica-and-calcium-aluminate-cement-fillers-increased-the-fluoride-recharge-and-lactic-acid-neutralizing-ability-of-a-resin-based-pit-and-fissure-sealant
#17
Atikom Surintanasarn, Krisana Siralertmukul, Niyom Thamrongananskul
This study evaluated the effect of different types of filler in a resin-based pit and fissure sealant on fluoride release, recharge, and lactic acid neutralization. Resin-based sealant was incorporated with 5% w/w of the following fillers: calcium aluminate cement (CAC), synthesized mesoporous silica (SI), a CAC and SI mixture (CAC+SI), glass-ionomer powder (GIC), and acetic acid-treated GIC (GICA). Sealant without filler served as control. The samples were immersed in deionized water or a lactic acid solution and the concentration of fluoride in the water, before and after fluoride recharge, and the lactic acid pH change, respectively, were determined...
July 12, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/28689366/micro-ct-and-fe-sem-enamel-analyses-of-calcium-based-agent-application-after-bleaching
#18
Mauricio Neves Gomes, Flávia Pires Rodrigues, Nick Silikas, Carlos Eduardo Francci
OBJECTIVES: The objective of the present study is to evaluate the effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on bleached enamel. MATERIALS AND METHODS: A bleaching agent (35% hydrogen peroxide) was applied, 4 × 8 min on premolar teeth (n = 8). A CPP-ACP paste was applied for 7 days. Prior and post-treatment, microtomography images were obtained and 3D regions of interest (ROIs) were selected, from outer enamel, extending to 110...
July 8, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28689018/optimizing-concentration-of-titanium-tetrafluoride-solution-for-human-dentine-remineralization
#19
Peng Wang, Jianghong Gao, Danyang Wang, Malcolm L Snead, Juedan Li, Jianping Ruan
OBJECTIVE: The aim of the present study was to select the optimal concentration of TiF4 solution to facilitate the remineralization of early dentine caries lesions. DESIGN: Sixty human dentine specimens were cut and randomly divided into 6 groups (1%, 2%, 3%, 4% TiF4 groups, 2.712% NaF group and distilled deionized water (DDW) control group). Artificial dentine caries-like lesions were created. After being subjected to fluoride treatment and immersed in remineralizing solution for 2weeks, the specimens were observed by microCT, scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS)...
July 1, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28681046/long-term-in-vivo-effect-of-various-restorative-materials-on-enamel-and-dentin-of-primary-molars
#20
Elyiahu Mass, Alla Hassan, Ornit Cohen, Uri Zilberman
OBJECTIVE: To explore the long-term in-vivo effect of different dental restorative materials on the surrounding enamel and dentin, in primary molars. METHOD AND MATERIALS: Sixteen naturally exfoliated primary molars restored with amalgam, compomer, and glass-ionomer cement were collected after 2 to 5 years of function in the mouth. Four intact molars served as control. The teeth were sliced buccolingually and the ion content in the restorative material, the enamel, and the dentin surrounding the restoration was determined using a scanning electron microscopy-energy dispersive x-ray spectroscopy (SEM-EDS) program...
July 4, 2017: Quintessence International
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