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Remineralization

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https://www.readbyqxmd.com/read/29125909/calcium-phosphate-microspheres-as-a-delivery-vehicle-for-tooth-bleaching-agents
#1
T Mellgren, T Qin, C Öhman-Mägi, Y Zhang, B Wu, W Xia, H Engqvist
Bleaching of vital teeth has become common practice in cosmetic dentistry today. Tooth sensitivity and demineralization of the enamel are, however, common side effects associated with hydrogen and carbamide peroxide bleaching. This study investigated if calcium phosphate microspheres, which have remineralizing properties, could be used as an additive without hindering the diffusion of the bleaching agent and if the spheres could be used as a carrier for carbamide peroxide. A remineralizing agent could increase the safety of bleaching and decrease the severity of its side effects...
November 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29117827/tuberculosis-of-the-elbow-region-in-pediatric-age-group-experiences-from-a-single-centre
#2
Anil Agarwal, Anuj Rastogi
BACKGROUND: Clinical series of tuberculosis of elbow region in children are few. The purpose of our study was to retrospectively review the presentation, healing response and functional results of 30 children. METHODS: The pretreatment disease presentation was studied from patient's case records. Serial radiographs of the patients were studied to see remineralization and healing of radiological lesions. For elbow's functional evaluation, pain, range of motion and recurrence were observed at final follow up...
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29109481/pelagic-barite-precipitation-at-micromolar-ambient-sulfate
#3
Tristan J Horner, Helena V Pryer, Sune G Nielsen, Peter W Crockford, Julia M Gauglitz, Boswell A Wing, Richard D Ricketts
Geochemical analyses of sedimentary barites (barium sulfates) in the geological record have yielded fundamental insights into the chemistry of the Archean environment and evolutionary origin of microbial metabolisms. However, the question of how barites were able to precipitate from a contemporary ocean that contained only trace amounts of sulfate remains controversial. Here we report dissolved and particulate multi-element and barium-isotopic data from Lake Superior that evidence pelagic barite precipitation at micromolar ambient sulfate...
November 7, 2017: Nature Communications
https://www.readbyqxmd.com/read/29104598/effect-of-proanthocyanidin-fluoride-and-casein-phosphopeptide-amorphous-calcium-phosphate-remineralizing-agents-on-microhardness-of-demineralized-dentin
#4
Zahra Khamverdi, Matin Kordestani, Ali Reza Soltanian
Objectives: The aim of this study was to evaluate the effect of dentin remineralization using proanthocyanidin (PA), fluoride varnish and casein phosphopeptide amorphous calcium phosphate (CPP-ACP) paste and their various combinations on microhardness of demineralized root dentin. Materials and Methods: One-hundred and twenty freshly extracted sound human premolars were selected and randomly divided into eight groups for dentin treatment as follows. C: Deionized water (control); PA: 6...
March 2017: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/29104386/effect-of-casein-phosphopeptide-amorphous-calcium-phosphate-and-calcium-sodium-phosphosilicate-on-artificial-carious-lesions-an-in-vitro-study
#5
Iqra Chaudhary, Abhay M Tripathi, Gunjan Yadav, Sonali Saha
Aim: To compare new remineralizing agents calcium sodium phosphosilicate paste and casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste with that of fluoridated toothpaste in remineralization of early carious lesions using scanning electron microscopy and energy-dispersive X-ray (SEM-EDX) analysis. Materials and methods: Sixty sound extracted premolars were collected and placed in demineralizing solution for 4 days to produce artificial carious lesions...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29079452/use-of-sodium-trimetaphosphate-in-the-inhibition-of-dentin-matrix-metalloproteinases-and-as-a-remineralizing-agent
#6
Rafael Simões Gonçalves, Polliana Mendes Candia Scaffa, Marina Ciccone Giacomini, Marília Afonso Rabelo Buzalaf, Heitor Marques Honório, Linda Wang
OBJECTIVES: Because of its ability to act as an antiproteolytic agent, the effect of sodium trimetaphosphate (STMP) against specific enzymes extracted from sound dentin and its performance under acidic challenge on demineralized dentin were investigated. METHODS: The antiproteolytic potential of STMP (0.5%, 1.0%, and 1.5%) was assessed in triplicate by zymography. For the evaluation of remineralization activity, 50 bovine-root dentin specimens were selected and randomly divided into 5 groups (n=10)...
October 24, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29071020/in-vitro-comparison-of-fluoride-gel-alone-and-in-combination-with-er-cr-ysgg-laser-on-reducing-white-spot-lesions-in-primary-teeth
#7
Fatemeh Molaasadollah, Mohammad Asnaashari, Fatemeh Mashhadi Abbas, Maral Jafary
Introduction: Laser therapy has been suggested as a method for caries-prevention, and ErCr:YSGG laser is increasingly used in dentistry. This study aimed to compare the efficacy of fluoride gel alone and in conjunction with Er,Cr:YSGG laser for remineralization of white spot lesions (WSLs) in primary teeth. Methods: This study was conducted on 20 primary teeth with WSLs extracted for orthodontic reasons. Three sections were made of each tooth at the site of WSLs. The surface area of WSLs was measured under a stereomicroscope at ×25 magnification...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29056869/engineered-peptide-repairs-defective-adhesive-dentin-interface
#8
Qiang Ye, Paulette Spencer, Esra Yuca, Candan Tamerler
Failure of dental composite restorations is primarily due to recurrent decay at the tooth-composite interface. At this interface, the adhesive and its bond with dentin is the barrier between the restored tooth and the oral environment. In vivo degradation of the bond formed at the adhesive/dentin (a/d) interface follows a cascade of events leading to weakening of the composite restoration. Here, a peptide-based approach is developed to mineralize deficient dentin matrices at the a/d interface. Peptides that have an inherent capacity to self-assemble on dentin and to induce calcium-phosphate remineralization are anchored at the interface...
May 2017: Macromolecular Materials and Engineering
https://www.readbyqxmd.com/read/29056184/evidence-for-biofilm-acid-neutralization-by-baking-soda
#9
Domenick T Zero
BACKGROUND: The generating of acids from the microbial metabolism of dietary sugars and the subsequent decrease in biofilm pH below the pH at which tooth mineral begins to demineralize (critical pH) are the key elements of the dental caries process. Caries preventive strategies that rapidly neutralize biofilm acids can prevent demineralization and favor remineralization and may help prevent the development of sugar-induced dysbiosis that shifts the biofilm toward increased cariogenic potential...
November 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/29051581/blue-carbon-stores-in-tropical-seagrass-meadows-maintained-under-green-turtle-grazing
#10
Robert A Johnson, Alexandra G Gulick, Alan B Bolten, Karen A Bjorndal
Seagrass meadows are important sites for carbon storage. Green turtles (Chelonia mydas) are marine megaherbivores that consume seagrass throughout much of their global range. With successful conservation efforts, turtle abundance will increase, leading to more meadows being returned to their natural grazed state. There is concern this may lead to a loss of carbon stored in these systems, but the effects of green turtle grazing on seagrass ecosystem carbon dynamics have not been investigated. Here we experimentally show that despite 79% lower net ecosystem production (NEP) following grazing (24...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29050028/management-of-cavitated-root-caries-lesions-minimum-intervention-and-alternatives
#11
Michael F Burrow, Margaret A Stacey
The prevalence of root caries among the elderly is increasing. The lesion shape can vary considerably from a broad shallow saucer-shape to a deeper defined cavity. The variety of shapes poses a series of complications when considering restorative management. This is accompanied with a paucity of clinical evidence on treatment techniques and clinical outcomes. The current philosophy centered on conservative management of root caries will most likely provide patients with the greatest chance of maintaining their teeth...
2017: Monographs in Oral Science
https://www.readbyqxmd.com/read/29050027/new-preventive-approaches-part-ii-role-of-dentin-biomodifiers-in-caries-progression
#12
Ana K Bedran-Russo, Camila A Zamperini
Dental caries is the most prevalent infectious chronic disease in children and adults. With a globally aging population, new demands in the management of dental caries are awakened by the rampant increase in the incidence of dental root caries. Like crown caries, root caries requires bacterial driven tissue demineralization followed by the degradation of the extracellular dentin matrix. Due to the complex composition and ultrastructure, preventive strategies targeting the mineral phase of dentin are insufficient for managing the prevention and progression of root caries...
2017: Monographs in Oral Science
https://www.readbyqxmd.com/read/29050026/new-preventive-approaches-part-i-functional-peptides-and-other-therapies-to-prevent-tooth-demineralization
#13
Marília Afonso Rabelo Buzalaf, Juliano Pelim Pessan
The limited effect of fluoride on root caries has prompted the study of new preventive therapies, which involve recently developed functional peptides, lasers, phosphate-based technologies, among several other approaches. Most of the specific peptides currently investigated have been developed based on the available information related to the protective action of salivary proteins, including statherin-derived peptides. Other peptides include 8DSS, self-assembling peptide P11-4, antimicrobial peptides, and casein phosphopeptides combined with amorphous calcium phosphate...
2017: Monographs in Oral Science
https://www.readbyqxmd.com/read/29050023/monitoring-of-root-caries-lesions
#14
Iain A Pretty
The early detection of root caries is essential for the implementation of appropriate preventive therapeutic regimes. Subsequent monitoring of lesions is required to determine the outcomes of such therapies. While much research activity has been seen in the detection and monitoring of enamel caries, this has not been seen in root caries - despite the possibilities for shorter clinical trials due to the more rapid remineralization and arrest of such lesions. The main stay of both clinical practice and research has been the use of visual tactile criteria including, hardness, texture, the presence or absence of cavitation, and color...
2017: Monographs in Oral Science
https://www.readbyqxmd.com/read/29050022/assessment-of-root-caries-lesion-activity-and-its-histopathological-features
#15
Thiago Saads Carvalho, Adrian Lussi
Despite certain similarities in the etiology of root caries (RC) and coronal caries, there are notable differences in their histology, namely with regard to the demineralization process, which should be taken into consideration when assessing lesion activity. In this chapter, we present the histological changes to the dentin and pulp, occurring physiologically or in response to caries lesions. We focus on the histological features specific to RC lesions, discussing the assessment of lesion activity. The physiological changes occurring to the dentin and pulp are the formation of secondary dentin and the sclerosis of dentin tubules, while tertiary dentin is formed during pathologic stimuli from caries lesions...
2017: Monographs in Oral Science
https://www.readbyqxmd.com/read/29050019/endogenous-enzymes-in-root-caries
#16
Tchilalo Boukpessi, Suzanne Menashi, Catherine Chaussain
Similar to coronal caries, root caries results from a disequilibrium of the de-remineralization balance in favor of the demineralization process. It mainly involves a bacterial shift in favor of an increase in the proportion of acidogenic and aciduric bacteria. This process permanently damages the dental mineralized tissues, namely the dental cementum and dentin. In addition to the demineralization and exposure of the dentin or the cementum organic matrix, acid production by cariogenic bacteria induces the activation of endogenous (host-derived) enzymes within the dentin and saliva...
2017: Monographs in Oral Science
https://www.readbyqxmd.com/read/29048704/hydroxyapatite-decreases-cytotoxicity-of-a-glass-ionomer-cement-by-calcium-fluoride-uptake-in-vitro
#17
Casiano Del Angel-Mosqueda, Rene Hernandez-Delgadillo, Osvelia E Rodríguez-Luis, María T Ramírez-Rodríguez, Silvia Munguía-Moreno, Norma V Zavala-Alonso, Juan M Solís-Soto, María A A Nakagoshi-Cepeda, Rosa I Sánchez-Nájera, Sergio E Nakagoshi-Cepeda, Claudio Cabral-Romero
BACKGROUND: Glass ionomer cements (GICs) are widely used in dentistry because of their remineralizing and cariostatic potential induced by fluoride. In vitro studies have reported cell toxicity triggered by GICs; however, the influence of hydroxyapatite (HAp) must be considered. The aim of this study was to evaluate the effect of HAp in decreasing the cytotoxicity of the GIC 3M Vitrebond in vitro. METHODS: Samples of 3M Vitrebond (powder, liquid and light-cured) were incubated in Dulbecco's modified Eagle's medium-Ham's F12 (DMEM-F12) for 24 hours at 37°C...
October 14, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/29035520/modeling-remineralization-of-desalinated-water-by-micronized-calcite-dissolution
#18
David Hasson, Larissa Fine, Abraham Sagiv, Raphael Semiat, Hilla Shemer
A widely used process for remineralization of desalinated water consists of dissolution of calcite particles by flow of acidified desalinated water through a bed packed with millimeter-size calcite particles. An alternative process consists of calcite dissolution by slurry flow of micron-size calcite particles with acidified desalinated water. The objective of this investigation is to provide theoretical models enabling design of remineralization by calcite slurry dissolution with carbonic and sulfuric acids...
November 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28987248/the-effect-of-mipaste-plus-and-reminpro-on-incipient-caries-using-diagnodent-and-sem-an-invitro-study
#19
Bassir Leila, Saeid Nemati, Hajalizadeh Neda, Mashallah Khanehmasjedi
BACKGROUND: The remineralization of early caries lesion has an effective role on decreasing caries. For initial remineralization of caries lesion, using Compounds of Casein phosphopeptides (CPP) in different studies has been proposed. REMINPRO including Fluoride, Xylitol and Calcium phosphate has just been offered in the market. This study aims to investigate the efficacy of Reminpro and MI paste plus in terms of remineralization of early enamel lesions. MATERIALS AND METHODS: In 15 samples of healthy enamels of the maxillary first premolar teeth and 15 samples of Primary Mandibular First Molar under the effect of demineralized gel, artificial caries has been created...
2017: Journal of the National Medical Association
https://www.readbyqxmd.com/read/28983253/a-novel-kinetic-method-to-measure-apparent-solubility-product-of-bulk-human-enamel
#20
Linda Hassanali, Ferranti S Wong, Richard J M Lynch, Paul Anderson
Introduction: Tooth enamel mineral loss is influenced by its solubility product value, which is fundamental to the understanding of de- and remineralization resulting from a carious or erosive challenge. Published pKsp values for human enamel and hydroxyapatite range from 110 to 126 suggesting a heterogeneous nature of enamel solubility. However, this range of values may also result from the variety of methods used, e.g., some authors reporting values for suspensions of enamel powder and others for bulk enamel...
2017: Frontiers in Physiology
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