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Remineralization

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https://www.readbyqxmd.com/read/28545439/distribution-of-white-spot-lesions-among-orthodontic-patients-attending-teaching-institutes-in-khartoum
#1
Maha Kamal Eltayeb, Yahia Eltayeb Ibrahim, Ikhlas Ali El Karim, Nada Mirghani Sanhouri
BACKGROUND: Fixed orthodontic appliances render teeth cleaning arduous, thus when orthodontic treatment is associated with inadequate oral hygiene practice, development of white spot lesions (WSLs) imposes a significant risk on the dentition. Salivary reservoir of calcium, magnesium, phosphorous and fluoride counteracts demineralization and encourages remineralization providing protection against caries challenge. The investigation of the factors leading to WSLs' development is mandatory for appropriate prevention strategies planning...
May 25, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28540937/dental-caries
#2
REVIEW
Nigel B Pitts, Domenick T Zero, Phil D Marsh, Kim Ekstrand, Jane A Weintraub, Francisco Ramos-Gomez, Junji Tagami, Svante Twetman, Georgios Tsakos, Amid Ismail
Dental caries is a biofilm-mediated, sugar-driven, multifactorial, dynamic disease that results in the phasic demineralization and remineralization of dental hard tissues. Caries can occur throughout life, both in primary and permanent dentitions, and can damage the tooth crown and, in later life, exposed root surfaces. The balance between pathological and protective factors influences the initiation and progression of caries. This interplay between factors underpins the classification of individuals and groups into caries risk categories, allowing an increasingly tailored approach to care...
May 25, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28535357/effects-of-composites-containing-bioactive-glasses-on-demineralized-dentin
#3
A Tezvergil-Mutluay, R Seseogullari-Dirihan, V P Feitosa, G Cama, D S Brauer, S Sauro
The aim of this study was to evaluate the degradation of completely demineralized dentin specimens in contact with a filler-free or 2 ion-releasing resins containing micrometer-sized particles of Bioglass 45S5 (BAG) or fluoride-containing phosphate-rich bioactive glass (BAG-F). Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were also used to evaluate the remineralization induced by the experimental ion-releasing resin-based materials. Dentin beams were totally demineralized in H3PO4 (10%) and placed in direct contact with a filler-free (RESIN) or 2 experimental ion-releasing resins (BAG or BAG-F) and immersed in artificial saliva (AS) up to 30 d...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28532089/a-poly-2-hydroxyethyl-methacrylate-based-resin-improves-the-dentin-remineralizing-ability-of-calcium-silicates
#4
Paola Taddei, Carlo Prati, Maria Giovanna Gandolfi
Bioactive polymeric composites have received great attention for their capability to remineralize the dentin tissue. This study was aimed at evaluating if a poly(HEMA-co-TEGDMA) resin (HEMA: 2-hydroxyethyl methacrylate; TEGDMA: triethyleneglycol dimethacrylate) may increase the in vitro apatite forming ability of a calcium silicate cement (CaSi), in view of developing a hydrophilic light-curable composite bio-remineralizing restorative material (R-CaSi). To this purpose, the following experiments were carried out: (1) In vitro apatite forming ability of R-CaSi and CaSi was comparatively assessed by micro-Raman spectroscopy after immersion of the cement disks in Dulbecco's Phosphate Buffered Saline (DPBS) at 37°C for 1-28days; (2) Previously demineralized human dentin slices were soaked for 7days in close contact with the CaSi and R-CaSi cements as well as poly(HEMA), poly(TEGDMA) and poly(HEMA-co-TEGDMA), and then were comparatively analyzed by IR spectroscopy...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28530844/developing-a-new-generation-of-antimicrobial-and-bioactive-dental-resins
#5
L Cheng, K Zhang, N Zhang, M A S Melo, M D Weir, X D Zhou, Y X Bai, M A Reynolds, H H K Xu
Dental caries is prevalent, and secondary caries causes restoration failures. This article reviews recent studies on developing a new generation of bioactive resins with anticaries properties. Extensive effects were made to develop new antimicrobial composites, bonding agents, and other resins containing quaternary ammonium methacrylates to suppress plaque buildup and bacterial acid production. The effects of alkyl chain length and charge density and the antimicrobial mechanisms for chlorhexidine, nano-silver, quaternary ammonium methacrylates, and protein-repellent agents were discussed...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28526130/poly-amido-amine-and-calcium-phosphate-nanocomposite-remineralization-of-dentin-in-acidic-solution-without-calcium-phosphate-ions
#6
Kunneng Liang, Han Zhou, Michael D Weir, Chongyun Bao, Mark A Reynolds, Xuedong Zhou, Jiyao Li, Hockin H K Xu
OBJECTIVE: Patients with dry mouth often have an acidic oral environment lacking saliva that provides calcium (Ca) and phosphate (P) ions. However, there has been no study on dentin remineralization by placing samples in an acidic solution without Ca and P ions. Previous studies used saliva-like solutions with neutral pH and Ca and P ions. Therefore, the objective of this study was to investigate a novel method of combining poly(amido amine) (PAMAM) with a composite of nanoparticles of amorphous calcium phosphate (NACP) on dentin remineralization in an acidic solution without Ca and P ions for the first time...
May 16, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28525257/self-etch-adhesive-as-a-carrier-for-acp-nanoprecursors-to-deliver-biomimetic-remineralization
#7
Zhifang Wu, Xiaokan Wang, Zhe Wang, Changyu Shao, Xiaoting Jin, Leiqing Zhang, Haihua Pan, Ruikang Tang, Baiping Fu
Lab biomineralization should be carried out in an actual clinical practice. This study evaluated self-etch adhesive as a carrier for amorphous calcium phosphate (ACP) nanoprecursors to continuously deliver biomimetic remineralization of self-assembly type I collagen and demineralized dentin. Si-containing ACP particles (Si-ACP) stabilized with polyaspartic acid (PAsp) were synthesized and characterized by transmission electron microscopy (TEM), scanning electron microscopy-energy-dispersive X-ray spectroscopy, Fourier transform infrared analysis, X-ray powder diffractometry, and X-ray phototelectron spectroscopy...
May 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28521107/formation-of-fluorohydroxyapatite-with-silver-diamine-fluoride
#8
M L Mei, F Nudelman, B Marzec, J M Walker, E C M Lo, A W Walls, C H Chu
Silver diamine fluoride (SDF) is found to promote remineralization and harden the carious lesion. Hydroxyapatite crystallization is a crucial process in remineralization; however, the role of SDF in crystal formation is unknown. We designed an in vitro experiment with calcium phosphate with different SDF concentrations (0.38, 1.52, 2.66, 3.80 mg/mL) to investigate the effect of this additive on the nucleation and growth of apatite crystals. Two control groups were also prepared-calcium phosphate (CaCl2·2H2O + K2HPO4 in buffer solution) and SDF (Ag[NH3]2F in buffer solution)...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28516412/optimization-of-adhesive-pastes-for-dental-caries-prevention
#9
Patteera Sodata, Apa Juntavee, Niwut Juntavee, Jomjai Peerapattana
Dental caries prevention products available on the market contain only remineralizing agents or antibacterial agents. This study aimed to develop adhesive pastes containing calcium phosphate and α-mangostin for dental caries prevention using the optimization technique. Calcium phosphate was used as a remineralizing agent, and extracted α-mangostin was used as an antibacterial agent. The effect of the independent variables, which were fumed silica, Eudragit(®) EPO, polyethylene glycol, and ethyl alcohol, on the responses was investigated...
May 17, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28514339/-increased-oral-fluid-remineraling-function-by-endogenous-and-exogenous-saturation-methods-of-its-mineral-complexes
#10
O G Avraamova, Yu A Ippolitov, Ya A Plotnikova, P V Seredin, D V Goloshapov, E O Aloshina
RELEVANCE: One of the most common problems in modern caries prevention is the development of techniques to increase tooth resistance to the effects of cariogenic factors. Therefore, research is needed to study the chemical composition of tissues like teeth and body fluids surrounding the tooth to prevent demineralization process. The purpose of determining the effectiveness of work- and correlation relationship between endo saturation exogenous methods oral liquid mineral complexes. MATERIAL AND METHODS: In 95 patients analyzed the chemical composition and structure of the oral fluid by IR spectroscopy...
2017: Stomatologii︠a︡
https://www.readbyqxmd.com/read/28512540/the-effects-of-three-remineralizing-agents-on-regression-of-white-spot-lesions-in-children-a-two-week-single-blind-randomized-clinical-trial
#11
Masoumeh Ebrahimi, Maryam Mehrabkhani, Farzaneh Ahrari, Iman Parisay, Maliheh Jahantigh
BACKGROUND: This study investigated the effect of three remineralizing agents on improving white spot lesions (WSLs). MATERIAL AND METHODS: This clinical trial included children who had at least one WSL on anterior teeth of upper or lower jaws. The participants were randomly assigned to 4 groups by treatment: 1) a cream containing casein phosphopeptide-amorphous calcium phosphate and fluoride (MI Paste Plus); 2) a cream containing hydroxyapatite and fluoride (Remin Pro); 3) a 2% sodium fluoride gel; and 4) usual home care (control)...
May 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28502026/dentin-remineralizing-ability-and-enhanced-antibacterial-activity-of-strontium-and-hydroxyl-ion-co-releasing-radiopaque-hydroxyapatite-cement
#12
R Jayasree, T S Sampath Kumar, S Mahalaxmi, Sireesha Abburi, Y Rubaiya, Mukesh Doble
Dental caries is an infection of the mineralized tooth structures that advances when acid secreted by bacterial action on dietary carbohydrates diffuses and dissolves the tooth mineral leading to demineralization. During treatment, clinicians often remove only the superficial infected tooth structures and retain a part of affected carious dentin to prevent excessive dentin loss and pulp exposure. Calcium hydroxide is used to treat the affected dentin because it is alkaline, induces pulp-dentin remineralization and decreases bacterial infection...
June 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28500516/nd-yag-laser-irradiation-associated-with-fluoridated-gels-containing-photo-absorbers-in-the-prevention-of-enamel-erosion
#13
Pereira Lgs, S H Joao-Souza, Sjc Bezerra, A B Borges, Acc Aranha, T Scaramucci
This study evaluated the combined effect of Nd:YAG laser irradiation and fluoridated gels containing photo absorbers against enamel erosion. Enamel specimens from bovine teeth were polished, eroded (10 min, with 1% citric acid, pH = 2.6), and randomly allocated into the experimental groups (n = 8), according to the different surface treatments: fluoridated gels (F: 9047 ppm F and F + Sn: 9047 ppm F and 3000 ppm Sn), with or without photo absorbers (E: erythrosine and MB: methylene blue), and associated or not with Nd:YAG laser irradiation (in contact; 0...
May 12, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28482551/synthesis-and-characterization-of-silver-phosphate-calcium-phosphate-mixed-particles-capable-of-silver-nanoparticle-formation-by-photoreduction
#14
Livia C Natale, Yvette Alania, Marcela C Rodrigues, Alyne Simões, Douglas N de Souza, Erick de Lima, Victor E Arana-Chavez, Thiago L R Hewer, Rochelle Hiers, Fernando L Esteban-Florez, Giancarlo E S Brito, Sharukh Khajotia, Roberto R Braga
Silver phosphate is a semi-conductor sensitive to UV-Vis radiation (<530nm). Exposure to radiation removes electrons from the oxygen valence shell, which are scavenged by silver cations (Ag(+)), forming metallic silver (Ag(0)) nanoparticles. The possibility of silver nanoparticle formation in situ by a photoreduction process was the basis for the application of mixed calcium phosphate/silver phosphate particles as remineralizing and antibacterial fillers in resin-based dental materials. Mixed phosphate particles were synthesized, characterized and added to a dimethacrylate resin in 20% or 30% mass fractions to investigate their efficacy as ion-releasing fillers for dental remineralization and antibacterial activity...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28482504/bioactive-glass-for-dentin-remineralization-a-systematic-review
#15
REVIEW
Delihta Fernando, Nina Attik, Nelly Pradelle-Plasse, Phil Jackson, Brigitte Grosgogeat, Pierre Colon
BACKGROUND AND OBJECTIVES: Strategies to achieve dentin remineralization is at present an important target of restorative dentistry. Remineralization of dentin by a bioactive material is complete only when the tissue regains its functionality. This is achieved when there is adequate apatite formation which most importantly translates into improved mechanical properties of dentin as a result of intrafibrillar mineralization. Bioactive glass (BAG) is a well-known implant material for bone regeneration and is proven to have excellent ability of apatite formation...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28469827/comparative-evaluation-of-nano-hydroxyapatite-preparation-and-calcium-sucrose-phosphate-on-microhardness-of-deciduous-teeth-after-iron-drop-exposure-an-in-vitro-study
#16
Nilesh Rathi, Rutika Baid, Sudhindra Baliga, Nilima Thosar
BACKGROUND: To evaluate and compare the microhardness of deciduous teeth treated with nano-hydroxyapatite and calcium sucrose phosphate after iron drop exposure. MATERIAL AND METHODS: Twenty healthy anterior deciduous teeth were collected and stored in 0.9% saline solution at room temperature. All the teeth were immersed in artificial saliva in an incubator shaker at 37° for an hour and then subjected to Vickers microhardness test at 100g load for 5 seconds. The teeth were then immersed in iron drop for 5 minutes, twice daily, rinsed with distilled water and kept in artificial saliva...
April 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28469825/correlation-between-micro-hardness-and-mineral-content-in-healthy-human-enamel
#17
Anna Akkus, Daniel Karasik, Renato Roperto
BACKGROUND: Enamel is the hardest and the stiffest tissue in the human body. The enamel undergoes multidirectional stresses, withstands multimillion chewing cycles, all while protecting the internal dentin and pulp from damage due to mechanical overload and exposure to the harsh chemical environment of the mouth. Raman spectroscopy allows to study enamel mineral content in a non-destructive and site-specific way. While Raman spectroscopy has been applied in other studies to assess tooth mineralization, there are no studies that examine the relationship between micro-hardness and mineral content of the untreated enamel...
April 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28461632/dental-faculty-accuracy-when-using-diagnostic-codes-a-pilot-study
#18
Jeanne C Sutton, Rose-Marie Fay, Carolyn P Huynh, Cleverick D Johnson, Liang Zhu, Ryan L Quock
The aim of this study was to examine the accuracy of dental faculty members' utilization of diagnostic codes and resulting treatment planning based on radiographic interproximal tooth radiolucencies. In 2015, 50 full-time and part-time general dentistry faculty members at one U.S. dental school were shown a sequence of 15 bitewing radiographs; one interproximal radiolucency was highlighted on each bitewing. For each radiographic lesion, participants were asked to choose the most appropriate diagnostic code (from a concise list of five codes, corresponding to lesion progression to outer/inner halves of enamel and outer/middle/pulpal thirds of dentin), acute treatment (attempt to arrest/remineralize non-invasively, operative intervention, or no treatment), and level of confidence in choices...
May 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/28419783/high-occurrence-of-bathyarchaeota-mcg-in-the-deep-sea-sediments-of-south-china-sea-quantified-using-newly-designed-pcr-primers
#19
Tiantian Yu, Qianyong Liang, Mingyang Niu, Fengping Wang
The archaeal phylum Bathyarchaeota, which is composed of a large number of diverse lineages, is widespread and abundant in marine sediments. Environmental factors that control the distribution, abundance, and evolution of this largely diversified archaeal phylum are currently unclear. In this study, a new pair of specific primers that target the major marine subgroups of bathyarchaeotal 16S rRNA genes was designed and evaluated to investigate the distribution and abundance of Bathyarchaeota in marine sediments...
April 17, 2017: Environmental Microbiology Reports
https://www.readbyqxmd.com/read/28416222/dentin-on-the-nanoscale-hierarchical-organization-mechanical-behavior-and-bioinspired-engineering
#20
REVIEW
Luiz E Bertassoni
OBJECTIVE: Knowledge of the structural organization and mechanical properties of dentin has expanded considerably during the past two decades, especially on a nanometer scale. In this paper, we review the recent literature on the nanostructural and nanomechanical properties of dentin, with special emphasis in its hierarchical organization. METHODS: We give particular attention to the recent literature concerning the structural and mechanical influence of collagen intrafibrillar and extrafibrillar mineral in healthy and remineralized tissues...
April 14, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
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