Adam J Tulling, Gertjan Lugthart, Miriam G Mooij, Caroline L H Brackel, Suzanne W J Terheggen-Lagro, Rianne Oostenbrink, Corinne M P Buysse, Simone Hashimoto, Wineke Armbrust, Michiel A G E Bannier, Jolita Bekhof, Helma B van Gameren-Oosterom, Han Hendriks, Marlies A van Houten, Jan W van der Linden, Ankie Lebon, Lonneke van Onzenoort-Bokken, Gerdien A Tramper-Stranders, Mirjam van Veen, Erik G J von Asmuth, Emilie P Buddingh
BACKGROUND: SARS-CoV-2 variant evolution and increasing immunity altered the impact of pediatric SARS-CoV-2 infection. Public health decision-making relies on accurate and timely reporting of clinical data. METHODS: This international hospital-based multicenter, prospective cohort study with real-time reporting was active from March 2020 to December 2022. We evaluated longitudinal incident rates and risk factors for disease severity. RESULTS: We included 564 hospitalized children with acute COVID-19 (n = 375) or multisystem inflammatory syndrome in children (n = 189) from the Netherlands, Curaçao and Surinam...
October 12, 2023: Pediatric Infectious Disease Journal