keyword
MENU ▼
Read by QxMD icon Read
search

Reviews

keyword
https://www.readbyqxmd.com/read/100001003/emergency-management-of-sepsis-the-simple-stuff-saves-lives
#1
David Sweet, Julian Marsden, Kendall Ho, Christina Krause, James A Russell
Many emergency departments have implemented sepsis protocols since the 2001 publication of results from the early goal-directed therapy trial, which showed early targeted resuscitation lowers mortality. As part of an attempt to improve clinical and operational outcomes for emergency departments across British Columbia, we reviewed sepsis management literature and considered sepsis protocol implementation in the province’s emergency departments. During the literature review we found that many observational studies confirmed an association between implementation of emergency sepsis protocols and decreased mortality...
May 2012: BC medical journal: BCMJ
https://www.readbyqxmd.com/read/29228512/surgical-management-decreases-disease-recurrence-risk-in-recurrent-pyogenic-cholangitis
#2
Hwee Leong Tan, Ye Xin Koh, Weng Kit Lye, Ser Yee Lee, Brian Kim Poh Goh, Siong San Tan, Adrian Kah Heng Chiow, Chung Yip Chan
BACKGROUND: Recurrent pyogenic cholangitis (RPC) has a high risk of disease recurrence. We present our experience with RPC and examine the factors associated with disease recurrence. METHODS: We performed a retrospective review of all patients with RPC treated at two tertiary institutions between January 1990 and December 2013. Patients with liver atrophy and/or abscess were categorized as being associated with parenchymal disease (PD). RESULTS: We studied 157 patients with a median age of 59...
December 11, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29228472/the-epidemiology-of-stroke-in-africa-a-systematic-review-of-existing-methods-and-new-approaches
#3
REVIEW
Mayowa Owolabi, Paul Olowoyo, Femi Popoola, Daniel Lackland, Carolyn Jenkins, Oyedunni Arulogun, Rufus Akinyemi, Odunayo Akinyemi, Onoja Akpa, Olanrewaju Olaniyan, Ezinne Uvere, Issa Kehinde, Anbesaw Selassie, Mulugeta Gebregziabher, Raelle Tagge, Bruce Ovbiagele
Accurate epidemiological surveillance of the burden of stroke is direly needed to facilitate the development and evaluation of effective interventions in Africa. The authors therefore conducted a systematic review of the methodology of stroke epidemiological studies conducted in Africa from 1970 to 2017 using gold standard criteria obtained from landmark epidemiological publications. Of 1330 articles extracted, only 50 articles were eligible for review grouped under incidence, prevalence, case-fatality, health-related quality of life, and disability-adjusted life-years studies...
December 11, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29228471/mass-spectrometry-for-protein-sialoglycosylation
#4
REVIEW
Qiwei Zhang, Zack Li, Yawei Wang, Qi Zheng, Jianjun Li
Sialic acids are a family of structurally unique and negatively charged nine-carbon sugars, normally found at the terminal positions of glycan chains on glycoproteins and glycolipids. The glycosylation of proteins is a universal post-translational modification in eukaryotic species and regulates essential biological functions, in which the most common sialic acid is N-acetyl-neuraminic acid (2-keto-5-acetamido-3,5-dideoxy-D-glycero-D-galactononulopyranos-1-onic acid) (Neu5NAc). Because of the properties of sialic acids under general mass spectrometry (MS) conditions, such as instability, ionization discrimination, and mixed adducts, the use of MS in the analysis of protein sialoglycosylation is still challenging...
December 11, 2017: Mass Spectrometry Reviews
https://www.readbyqxmd.com/read/29228467/neoadjuvant-systemic-therapy-for-regionally-advanced-melanoma
#5
James W Jakub, Jennifer M Racz, Tina J Hieken, Alexandra B Gonzalez, Lisa A Kottschade, Svetomir N Markovic, Yiyi Yan, Mathew S Block
BACKGROUND: Patients with regionally advanced melanoma are at high risk of distant failure and unlikely to be cured by surgery alone. Neoadjuvant therapy may provide benefit in these patients. OBJECTIVES: To evaluate our experience with neoadjuvant systemic therapy in high-risk stage III patients. METHODS: Retrospective review of patients with advanced stage III disease who received neoadjuvant therapy between August 2009 and August 2016 at Mayo Clinic Rochester...
December 11, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29228466/concomitant-organ-resection-does-not-improve-outcomes-in-primary-retroperitoneal-well-differentiated-liposarcoma-a-retrospective-cohort-study-at-a-major-sarcoma-center
#6
Naruhiko Ikoma, Christina L Roland, Keila E Torres, Yi-Ju Chiang, Wei-Lien Wang, Neeta Somaiah, Gary N Mann, Kelly K Hunt, Janice N Cormier, Barry W Feig
BACKGROUND: We investigated whether concomitant organ removal as part of the primary resection of RP WDLPS confers an outcome advantage in patients treated at a major sarcoma center. METHODS: The departmental sarcoma database was reviewed to identify patients with RP WDLPS who underwent initial surgical resection for primary disease at MD Anderson Cancer Center during the study period 1995-2011. We retrospectively reviewed medical records and examined associations between clinicopathologic variables and overall survival (OS) as well as disease-free survival (DFS)...
December 11, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29228463/transition-metal-catalyzed-selective-functionalization-of-c-sp3-h-bonds-in-natural-products
#7
Rashad R Karimov, John F Hartwig
Direct functionalization of natural products is important for studying structure-activity and structure-property relationships of these molecules. Recent advances in transition-metal-catalyzed functionalizations of C(sp3)-H bonds, the most abundant yet inert bonds in natural products, have been shown to create natural product derivatives selectively. Strategies to achieve such transformation are reviewed.
December 11, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29228461/imaging-of-liposarcomas-for-clinicians-characteristic-features-and-differential-considerations
#8
REVIEW
Oluwadamilola Teniola, Kevin Yuqi Wang, Wei-Lien Wang, WilliamW Tseng, Behrang Amini
Liposarcoma (LPS) is a malignancy of fat and one of the most common soft tissue sarcomas. There are three major subtypes of LPS: Well-differentiated / dedifferentiated, myxoid, and pleomorphic. We review the imaging features of LPS in the abdomen and extremities, describe features that help differentiate the subtypes, and provides alternative considerations for fat-containing lesions (many benign) that can mimic LPS.
December 11, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29228442/a-novel-boswellic-acids-delivery-form-casperome%C3%A2-in-the-management-of-musculoskeletal-disorders-a-review
#9
A Riva, P Allegrini, F Franceschi, S Togni, L Giacomelli, R Eggenhoffner
Standard pharmacological treatment of musculoskeletal conditions is often associated with relevant side effects. Botanical preparations endowed with a good tolerability profile, therefore, could have a role in the management of these disorders. Among different natural products, Boswellia serrata extracts have long been used for the treatment of musculoskeletal disorders, given their marked anti-inflammatory activity and their ability to promote tissue regeneration. However, standard preparations of Boswellia serrata show overall modest pharmacokinetic properties, a limitation which may ultimately lead to reduced efficacy...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29228435/review-of-recent-advances-in-the-management-of-hypertrophic-cardiomyopathy
#10
Y Cao, P-Y Zhang
Hypertrophic cardiomyopathy (HCM) is a complex but common monogenic cardiovascular disorder characterized by unexplained non dilated left ventricular (LV) thickening in the absence of another cardiac or systemic disease. The condition is associated with sudden and unexpected death in young individuals including trained athletes. HCM represents a genetic disorder caused by mutations in genes encoding sarcomeric proteins of the cardiac myocyte. This review article discusses the genetics behind HCM, its clinical presentation, and diagnosis and the present-day pharmacological management of HCM...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29228434/functional-roles-of-exosomes-in-cardiovascular-disorders-a-systematic-review
#11
H-J Sun, X-X Zhu, W-W Cai, L-Y Qiu
Cardiovascular diseases are major causes of people death associated with high mortality and disability. Exosomes are nanosized extracellular vesicles containing protein, lipid, transcription factors, mRNAs, non-coding RNA (ncRNA) and nucleic acid contents, which are critical players of intercellular communication via long-range signals or cell-to-cell contact. The emergence of exosomes provides favorable strategies for the diagnosis and treatment of cardiovascular diseases. Exosomes-based molecular mechanisms are important for developing novel therapeutic approaches for cardiovascular events...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29228431/the-association-of-pancreatic-cystosis-and-ipmn-in-cystic-fibrosis-case-report-and-literature-review
#12
D Pagliari, A Saviano, M L Serricchio, A A Dal Lago, M G Brizi, R Manfredi, G Costamagna, F Attili
Pancreatic cystosis is a rare presentation of cystic fibrosis involving pancreatic gland. To date, only very few cases of pancreatic cystosis have been described in literature. Pancreatic cystosis may begin during the second decade of life and is the rarest presentation of cystic fibrosis. This disease is characterized by the presence of multiloculated cysts without ductal system communication of different sizes in all the pancreatic tissue. Herein, we report a case of a young woman affected by cystic fibrosis that was admitted to our Pancreatic Centre to evaluate a picture of diffuse multiloculated pancreatic cysts...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29228407/-sport-after-total-knee-and-hip-arthroplasty
#13
Friedrich Boettner, Maximilian F Kasparek, Kilian Rueckl, Christian Liebau
The introduction of new materials and better implant coatings seems to provide the prerequisites for more intense physical activities after total joint arthroplasties of the lower extremity. Despite recent advances in implant design and materials, recommendations for sport after total joint arthroplasty have not been updated over the past 20 years. The introduction of modern uncemented fixation as well as highly cross-linked polyethylene into total hip arthroplasty allow for a more active life-style without an increased risk of loosening or complications...
December 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/29228403/anterior-cruciate-ligament-mechanoreceptors-and-their-potential-importance-in-remnant-preserving-reconstruction-a-review-of-basic-science-and-clinical-findings
#14
Jonathan David Kosy, Vipul I Mandalia
No abstract text is available yet for this article.
December 11, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29228399/effects-of-glucose-and-sucrose-on-mood-a-systematic-review-of-interventional-studies
#15
Ondine van de Rest, Nikita L van der Zwaluw, Lisette C P G M de Groot
Context: Glucose is the main energy source for the brain, and as such, manipulation of glucose supply may affect brain function. It has been suggested that a change in blood glucose may influence mood. Objective: The aim of this review was to investigate the potential effects of glucose and sucrose, compared with placebo, on mood. Data Sources: The electronic databases PubMed and Scopus were searched. Reference lists of selected articles were checked manually...
December 8, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29228398/organophosphorus-compounds-at-80-some-old-and-new-issues
#16
Lucio G Costa
One of the major classes of pesticides is that of the organophosphates (OPs). Initial developments date back almost two centuries but it was only in the mid-1940s that OPs reached a prominent status as insecticides, a status that, albeit declining, is still ongoing. OPs are highly toxic to non-target species including humans, the primary effects being an acute cholinergic toxicity (responsible for thousands of poisoning each year) and a delayed polyneuropathy. Several issues of current debate and investigation on the toxicology of OPs are discussed in this brief review...
December 7, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29228395/brain-stem-cavernous-malformations-operative-nuances-of-a-less-invasive-resection-technique
#17
Harminder Singh, Turki Elarjani, Harley Brito da Silva, Rakshith Shetty, Louis Kim, Laligam N Sekhar
BACKGROUND: Different operative techniques are reported for the resection of brainstem cavernous malformations (BSCMs). The senior author has previously reported on a less-invasive technique of entering the brain stem with piecemeal removal of BSCMs, especially the deep-seated ones. OBJECTIVE: To present a larger series of these lesions, emphasizing the approach to the brain stem via case selection. We discuss the nuances of the less-invasive operative technique through case illustrations and intraoperative videos...
December 8, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29228383/oral-fungal-bacterial-biofilm-models-in-vitro-a-review
#18
Marlene Chevalier, Stephane Ranque, Isabelle Prêcheur
Inclusion of fungi as commensals in oral biofilm is an important innovation in oral biology, and this work aimed to review the literature on the available biofilm and related disease in vitro models. Actually, thousands of bacterial and around one hundred of fungal phylotypes can colonize the oral cavity. Taxonomic profiling combined with functional expression analysis has revealed that Candida albicans, Streptococcus mutans and prominent periodontopathogens are not always present or numerically important in candidiasis, caries, or periodontitis lesions...
December 8, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29228348/flaxseed-supplementation-on-glucose-control-and-insulin-sensitivity-a-systematic-review-and-meta-analysis-of-25-randomized-placebo-controlled-trials
#19
Mohsen Mohammadi-Sartang, Zahra Sohrabi, Reza Barati-Boldaji, Hamidreza Raeisi-Dehkordi, Zohreh Mazloom
Context: The results of human clinical trials investigating the effects of flaxseed on glucose control and insulin sensitivity are inconsistent. Objective: The present study aimed to systematically review and analyze randomized controlled trials assessing the effects of flaxseed consumption on glycemic control. Data Sources: PubMed, Medline via Ovid, SCOPUS, EMBASE, and ISI Web of Sciences databases were searched up to November 2016. Study Selection: Clinical trials in which flaxseed or its products were administered as an intervention were included...
December 8, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29228346/the-use-of-ultrasound-in-detecting-and-defining-ground-glass-opacities-results-of-an-ex-vivo-evaluation
#20
Alfonso Fiorelli, Gaetana Messina, Elisabetta Frongillo, Marina Accardo, Marco Montella, Iacopo Panarese, Renato Franco, Mario Santini
OBJECTIVES: To evaluate the role of ultrasound in detecting and defining ground-glass opacities (GGOs) in surgical specimens of patients undergoing thoracoscopic diagnostic resection. METHODS: We performed an observational single-centre study of all consecutive patients undergoing thoracoscopic diagnostic resection of GGOs. In each patient, the specimen was scanned with ultrasound; then, a needle was inserted into the lesion to facilitate its detection by the pathologist...
December 8, 2017: Interactive Cardiovascular and Thoracic Surgery
keyword
keyword
2951
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"