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https://www.readbyqxmd.com/read/29232688/genotype-and-cell-specific-dynamics-of-tandem-repeat-patterns-in-aegilops-speltoides-tausch-poaceae-triticeae
#1
Olga Raskina
In wild plant populations, chromosome rearrangements lead to the wide intraspecific polymorphisms in the abundance and patterns of highly repetitive DNA. However, despite the large amount of accumulated data, the impact of the complex repetitive DNA fraction on genome reorganization and functioning and the mechanisms balancing and maintaining the structural integrity of the genome are not fully understood. Homologous recombination is thought to play a key role in both genome reshuffling and stabilization, while the contribution of nonhomologous recombination seems to be undervalued...
December 13, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/29232623/determinants-of-child-maltreatment-in-nepal-results-from-the-2014-nepal-multiple-indicator-cluster-survey-the-2014-nmics
#2
Madhu Sudhan Atteraya, Nasser B Ebrahim, Shreejana Gnawali
We examined the prevalence of child maltreatment as measured by the level of physical (moderate to severe) and emotional abuse and child labor, and the associated household level determinants of child maltreatment in Nepal. We used a nationally representative data set from the fifth round of the Nepal Multiple Indicator Cluster Survey (the 2014 NMICS). The main independent variables were household level characteristics. Dependent variables included child experience of moderate to severe physical abuse, emotional abuse, and child labor (domestic work and economic activities)...
December 9, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29232565/parental-bonding-and-adolescents-depressive-and-anxious-symptoms-in-pakistan
#3
Amna Khalid, Farah Qadir, Stella W Y Chan, Matthias Schwannauer
INTRODUCTION: A quantitative cross sectional study was carried out to investigate the role of parental bonding in relation to depressive and anxious symptoms among secondary school adolescents in Pakistan. The study also aimed to investigate the construct validity of the parental bonding inventory in the cultural context of Pakistan. METHODS: The sample consisted of 1124 adolescents recruited from eight secondary schools in Rawalpindi, Pakistan. Urdu translated versions of Parental Bonding Instrument (Qadir et al...
November 21, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29232526/prevention-of-childhood-obesity-in-child-health-services-follow-up-of-the-primrose-trial
#4
Johanna Enö Persson, Benjamin Bohman, Per Tynelius, Finn Rasmussen, Ata Ghaderi
BACKGROUND: Childhood obesity is an urgent public health concern, and there's a need for long-term, high-quality, primary prevention trials targeting parents of young children. The aim of the current study was to evaluate the long-term effect of a parental support program based on motivational interviewing (MI). METHODS: A cluster randomized controlled trial was carried out in eight Swedish counties. Participating families (N = 1355) were enrolled when the child was 9 months old, and participated in nine sessions during ∼39 months...
December 12, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/29232351/randomized-clinical-trial-of-lidocaine-analgesia-for-transurethral-bladder-catheterization-delivered-via-blunt-tipped-applicator-in-young-children
#5
Neil G Uspal, Bonnie Strelitz, Jesse Gritton, Kristin Follmer, Miranda C Bradford, Taryn L Colton, Paul A Merguerian, Eileen J Klein
OBJECTIVE: Transurethral bladder catheterization (TUBC) is a painful, frequently performed procedure for collecting sterile urine. We sought to determine if administration of intraurethral lidocaine before TUBC using a blunt tipped syringe decreases procedural pain in young children in the pediatric emergency department. METHODS: Randomized clinical trial of children 0 to 36 months old requiring TUBC for collection of urine in a pediatric emergency department was performed...
December 11, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29232180/a-randomized-study-of-a-mobile-behavioral-parent-training-application
#6
Edward G Feil, Peter G Sprengelmeyer, Craig Leve
Background/Introduction: Never before have parents had such immediate access to parenting support. The extension of the Internet to smartphones, offers the opportunity to provide families with the highest-quality information at the time and place that it can be the most useful. However, there remain considerable barriers to getting the right information to the right people at the right time. MATERIALS AND METHODS: This study includes the initial feasibility testing of a smartphone application "ParentNet" that attempts to deliver on the potential of empirically supported therapy by connecting family members with specific behavioral goals and outcomes in real time...
December 12, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/29232133/alkali-metal-trihalides-m-x3-ion-pair-or-mx-x2-complex
#7
Zhi Sun, Kevin B Moore, J Grant Hill, Kirk A Peterson, Henry F Schaefer, Roald Hoffmann
The alkali metal trihalides MX3 (M = Li, Na, K, Rb, and Cs; X = Cl, Br, and I) are systematically studied using coupled-cluster methods. Benchmarks using CCSD(T) against diatomic experimental results suggest satisfactory performance for the weighted core-valence basis sets (new basis sets for K, Rb, and Cs) selected for predicting reliable structures and harmonic vibrational frequencies. An isomer search using the B3LYP functional yields a planar, yet asymmetric T-shaped Cs structure as the global minimum for all MX3 species...
December 12, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/29232016/characterization-of-h3-3-and-hira-expression-and-function-in-bovine-early-embryos
#8
Kun Zhang, Han Wang, Sandeep K Rajput, Joseph K Folger, George W Smith
Histone variant H3.3 is encoded by two distinct genes, H3F3A and H3F3B, that are closely associated with actively transcribed genes. H3.3 replacement is continuous and essential for maintaining correct chromatin structure during mouse oogenesis. Upon fertilization, H3.3 is incorporated to parental chromatin, and is required for blastocyst formation in mice. The H3.3 exchange process is facilitated by the chaperone HIRA, particularly during zygote development. We previously demonstrated that H3.3 is required for bovine early embryonic development; here, we explored the mechanisms of its functional requirement...
December 12, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/29231989/sexual-imprinting-and-speciation-in-two-peromyscus-species
#9
E K Delaney, H E Hoekstra
Sexual isolation, a reproductive barrier, can prevent interbreeding between diverging populations or species. Sexual isolation can have a clear genetic basis; however, it may also result from learned mate preferences that form via sexual imprinting. Here, we demonstrate that two sympatric species of mice-the white-footed mouse (Peromyscus leucopus) and its sister species, the cotton mouse (P. gossypinus)-hybridize only rarely in the wild despite co-occurrence in the same habitat and lack of any measurable intrinsic postzygotic barriers in laboratory crosses...
December 12, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/29231970/adaptation-of-the-utrecht-management-of-identity-commitments-scale-u-mics-to-the-measurement-of-the-parental-identity-domain
#10
Konrad Piotrowski
The present studies examined the psychometric properties of the Utrecht-Management of Identity Commitments Scale (U-MICS) adapted to the measurement of identity formation in the parental identity domain. As the parental identity domain has only been studied within the neo-Eriksonian approach to a very limited extent, the aim of these studies was to prepare a short, valid and reliable tool for the measurement of parental identity in order to fill this gap. The associations of commitment, in-depth exploration and reconsideration of commitment in the parental domain with well-being and with other identity constructs were analyzed...
December 12, 2017: Scandinavian Journal of Psychology
https://www.readbyqxmd.com/read/29231856/involvement-of-udp-glucuronosyltransferases-and-sulfotransferases-in-the-excretion-and-tissue-distribution-of-resveratrol-in-mice
#11
Michaela Böhmdorfer, Akos Szakmary, Robert H Schiestl, Javier Vaquero, Juliane Riha, Stefan Brenner, Theresia Thalhammer, Thomas Szekeres, Walter Jäger
Resveratrol is a naturally occurring polyphenolic compound with various pharmacological activities. It is unknown whether the expression of metabolizing enzymes correlates with resveratrol levels in organs and tissues. Therefore, we investigated the metabolism and tissue distribution of resveratrol in mice and assessed its association with the expression of UDP-glucuronosyltransferase (Ugt) and sulfotransferase (Sult) genes. Plasma, urine, feces, and various organs were analyzed using high-performance liquid chromatography at up to 8 h after intragastric resveratrol administration...
December 12, 2017: Nutrients
https://www.readbyqxmd.com/read/29231249/analysis-of-the-costs-of-veterinary-education-and-factors-associated-with-financial-stress-among-veterinary-students-in-australia
#12
K P Gregory, S M Matthew, J A Baguley
OBJECTIVE: To investigate the course-related and other costs involved in obtaining a veterinary education in Australia and how these costs are met. The study also aimed to identify sociodemographic and course-related factors associated with increased financial stress. METHODS: Students from seven Australian veterinary schools were surveyed using an online questionnaire. A total of 443 students participated (response rate 17%). Responses to survey items relating to finances, employment and course-related costs were compared with sociodemographic factors and prior research in the area of student financial stress...
December 12, 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/29231138/cholinesterase-inhibitor-6-chlorotacrine-in-vivo-toxicological-profile-and-behavioural-effects
#13
Jan Misik, Eugenie Nepovimova, Jaroslav Pejchal, Jiri Kassa, Jan Korabecny, Ondrej Soukup
BACKGROUND: 6-chlorotacrine is a cholinesterase inhibitor showing good inhibitory potential, even better than parent compound tacrine, in vitro. Despite tacrine scaffold is broadly used for design and synthesis of novel compounds with anti-Alzheimer's potential, no in vivo effects have been investigated so far. Thus, basic toxicological and behavioural evaluation has been carried out throughout this study. METHODS: Maximum tolerated dose (MTD) and median lethal dose (LD50) were assessed in BALB/c mice and Wistar rats...
December 11, 2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/29231046/an-assessment-of-the-effects-of-hydrotherapy-during-the-active-phase-of-labor-on-the-labor-process-and-parenting-behavior
#14
Semra Tuncay, Sena Kaplan, Ozlem Moraloglu Tekin
This study was conducted to assess the effect on labor process and parenting behavior of hydrotherapy applied during the active phase of labor. This quasi-experimental study was conducted by using an equivalent comparison group ( n = 40). The participants in the experimental group whose cervical dilation was 5 cm were taken to the hydrotherapy tub. This application continued until cervical dilation reached 10 cm. The Participants Questionnaire, The Birth Follow-up Questionnaire, The Postpartum ]collection tools...
December 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/29231028/-confirming-indicators-of-qualitative-results-by-chromatography-mass-spectrometry-in-biological-samples
#15
REVIEW
S D Liu, D M Zhang, W Zhang, W F Zhang
Because of the exist of complex matrix, the confirming indicators of qualitative results for toxic substances in biological samples by chromatography-mass spectrometry are different from that in non-biological samples. Even in biological samples, the confirming indicators are different in various application areas. This paper reviews the similarities and differences of confirming indicators for the analyte in biological samples by chromatography-mass spectrometry in the field of forensic toxicological analysis and other application areas...
April 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29230987/-comparison-of-criminal-characteristics-in-depression-patients-and-schizophrenics-with-homicide-behavior
#16
J Wang, P X Fu, Y L Gao, M X Zhu, T T Shi
OBJECTIVES: To explore the criminal characteristics of forensic psychiatry expertise in depression patients and schizophrenics with homicide behavior. METHODS: A total of 40 depression (depressive episode) patients and 50 schizophrenics with homicide behavior were randomly assigned into the study group and control group, respectively. Data of demographic and criminal characteristic of the two groups were collected by a self-designed questionnaire, and then were compared...
June 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29230934/adult-children-of-parents-with-mental-illness-dehumanization-of-a-parent-she-wasn-t-the-wreck-in-those-years-that-she-was-to-become-later
#17
Gillian Murphy, Kath Peters, Lesley Wilkes, Debra Jackson
Children who have lived with parental mental illness experience long-standing reduced health and social outcomes, alongside ongoing personal distress. While there has been some dialogue regarding interventions to support children who are living with parental mental illness, there remains a paucity of knowledge regarding adult children's experiences and potential needs. Given this, the aim of the present study was to establish parenting narratives of adult children who had experienced childhood parental mental illness...
December 11, 2017: International Journal of Mental Health Nursing
https://www.readbyqxmd.com/read/29230919/parents-pain-medication-underdosing-is-associated-with-more-emergency-department-visits-in-sickle-cell-disease
#18
Andrea K Morrison, Matthew P Myrvik, David C Brousseau, Amy L Drendel, J Paul Scott, Alexis Visotcky, Julie A Panepinto
OBJECTIVE: To determine the association between health literacy, medication knowledge, and pain treatment skills with emergency department (ED) use of parents of children with sickle cell disease (SCD). METHODS: Parents of children 1- to 12-years-old with SCD were enrolled. Health literacy was assessed using the Newest Vital Sign. Parents completed a structured interview assessing knowledge of the dosage and frequency of home pain medications and an applied skills task requiring them to dose a prescribed pain medication...
December 12, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29230806/comparing-the-characteristics-and-outcomes-of-parent-and-teacher-reported-oppositional-defiant-disorder-findings-from-a-national-sample
#19
James McNeilis, Barbara Maughan, Robert Goodman, Richard Rowe
BACKGROUND: Parents and teachers often disagree on the presence of Oppositional Defiant Disorder (ODD) in children. It has been argued that ODD should be treated as an informant-specific disorder. This study compared the characteristics of children identified with ODD by parent- and teacher report. METHODS: We used the 1999 British Child and Adolescent Mental Health Survey, including more than 10,000 observations aged 5-15 years, to investigate symptom profiles, risk factors, comorbidities and three-year outcomes of parent- and teacher-reported ODD...
December 12, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29230802/measurement-properties-of-instruments-that-assess-participation-in-young-people-with-autism-spectrum-disorder-a-systematic-review
#20
REVIEW
Francesca Lami, Kristine Egberts, Alexandra Ure, Rowena Conroy, Katrina Williams
AIM: To systematically review the measurement properties of instruments assessing participation in young people with autism spectrum disorder (ASD). METHOD: A search was performed in MEDLINE, PsycINFO, and PubMed combining three constructs ('ASD', 'test of participation', 'measurement properties'). Results were restricted to articles including people aged 6 to 29 years. The 2539 identified articles were independently screened by two reviewers. For the included articles, data were extracted using standard forms and their risk of bias was assessed...
December 12, 2017: Developmental Medicine and Child Neurology
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