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Early childhood caries

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https://www.readbyqxmd.com/read/28721668/quantitative-analysis-of-s-mutans-lactobacillus-and-bifidobacterium-found-in-initial-and-mature-plaques-in-thai-children-with-early-childhood-caries
#1
K Mitrakul, S Chanvitan, A Jeamset, K Vongsawan
AIMS: To quantify Streptococcus mutans, lactobacillus and bifidobacterium in initial and mature plaque collected from children with severe early childhood caries (S-ECC) and caries-free (CF) groups and to analyse the association between these bacteria and caries-related factors in each group. STUDY DESIGN: A collection of 120 initial and overnight supra-gingival plaques were collected from Thai children aged 2-5 years-old (S-ECC = 60, CF = 60). Plaque, gingival indices and decayed, missing, filled tooth (dmft) scores were recorded...
July 18, 2017: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28713800/strategies-for-meaningful-engagement-between-community-based-health-researchers-and-first-nations-participants
#2
Jaime Cidro, Marion Maar, Sabrina Peressini, Robert J Schroth, John Broughton, Lisa Jamieson, Herenia P Lawrence
The Baby Teeth Talk Study (BTT) is a partnership-based research project looking at interventions to prevent early childhood caries (ECC) in First Nations populations in Canada. Community-based researchers (CBRs) conducted preventive and behavioral interventions that targeted expectant mothers and their newborns, over a 3-year period. The work of the CBRs requires a great deal of training and skills to administer the interventions. It also requires a broad set of strategies to meaningfully engage participants to make health-promoting changes in their behavior to prevent ECC in their children...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28709424/genotypic-diversity-and-phenotypic-traits-of-streptococcus-mutans-isolates-and-their-relation-to-severity-of-early-childhood-caries
#3
Remberto Marcelo Argandoña Valdez, Cristiane Duque, Karina Sampaio Caiaffa, Vanessa Rodrigues Dos Santos, Maria Luiza de Aguiar Loesch, Natalia Helena Colombo, Rodrigo Alex Arthur, Thais de Cássia Negrini, Marcelo Fabiano Gomes Boriollo, Alberto Carlos Botazzo Delbem
BACKGROUND: Early childhood caries (ECC) is an aggressive condition that can affect teeth of young children. This study aimed to evaluate genotypic diversity and phenotypic traits of S. mutans isolated from dental biofilms of children with different caries status in comparison with caries free (CF) children. METHODS: Streptococcus mutans strains were isolated from supragingival biofilm samples of CF, ECC and severe-ECC (S-ECC) children and genotyped by arbitrary-primer polymerase chain reaction - AP-PCR...
July 14, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28709393/microbiome-associated-with-severe-caries-in-canadian-first-nations-children
#4
M Agnello, J Marques, L Cen, B Mittermuller, A Huang, N Chaichanasakul Tran, W Shi, X He, R J Schroth
Young Indigenous children in North America suffer from a higher degree of severe early childhood caries (S-ECC) than the general population, leading to speculation that the etiology and characteristics of the disease may be distinct in this population. To address this knowledge gap, we conducted the first microbiome analysis of an Indigenous population using modern molecular techniques. We investigated the caries-associated microbiome among Canadian First Nations children with S-ECC. Thirty First Nations children <72 mo of age with S-ECC and 20 caries-free children were recruited in Winnipeg, Canada...
July 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28705197/genetic-polymorphism-of-scra-gene-of-streptococcus-mutans-isolates-is-not-associated-with-biofilm-formation-in-severe-early-childhood-caries
#5
Yan Zhou, Lixia Yu, Ye Tao, Qinghui Zhi, Huancai Lin
BACKGROUND: To explore and analyse the association between biofilm and the genetic polymorphisms of scrA gene of EnzymeIIscr found in clinical isolates of Streptococcus mutans (S. mutans) from severe early childhood caries (S-ECC) in 3 years old children. METHODS: Clinical strains of S. mutans were conserved from a previous study. Thirty strains of S. mutans from the S-ECC group and 30 strains of S. mutans from the caries free (CF) group were selected. Biomass and viability of biofilm formed by the strains were evaluated by crystal violet and alamar blue assay...
July 14, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28702057/role-of-fluoride-varnish-in-preventing-early-childhood-caries-a-systematic-review
#6
REVIEW
Poulami Mishra, Nusrath Fareed, Hemant Battur, Sanjeev Khanagar, Manohar A Bhat, Jagan Palaniswamy
BACKGROUND: Early childhood caries is a public health problem that continues to affect babies and preschool children worldwide. This untreated caries process results in progressive destruction of the crowns of the teeth, often accompanied by severe pain and suffering, affecting the quality of life. Fluoride varnish which is one of the most important materials to prevent ECC is easy to apply and well tolerated by children. This study aimed to evaluate the scientific evidence regardingthe role of fluoride varnish in preventing early childhood caries...
May 2017: Dental Research Journal
https://www.readbyqxmd.com/read/28698734/methods-of-biotyping-of-streptococcus-mutans-species-with-the-routine-test-as-a-prognostic-value-in-early-childhood-caries
#7
Wirginia Krzyściak, Dorota Kościelniak, Monika Papież, Anna Jurczak, Palina Vyhouskaya
PURPOSE: In order to investigate the suitability of Streptococcus mutans species biotyping by measuring the activity of selected enzymes from a commercial test, criteria were established for biotyping clinical strains from children with dental caries. In addition, the relationships between the selected biotypes, sensitivity to commonly used antibiotics, and early childhood caries were determined. METHODS: A total of 142 S. mutans isolates from dental plaque of children with caries were divided into different biotypes...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28676047/a-longitudinal-study-of-early-childhood-caries-incidence-in-wenzhou-preschool-children
#8
Xiping Wang, Zhiyuan Wei, Qiao Li, Liqin Mei
BACKGROUND: Early childhood caries (ECC) is a serious public health problem in China. Few studies, however, have described the incidence of ECC in China. The purpose of this study was to assess the prevalence and incidence of ECC among preschool children in Wenzhou China. METHODS: Preschool children aged 3-4 years old were surveyed and followed up when they reached 5-6 years of age in the city of Wenzhou in southeast China. The rates of dental caries were determined with prevalence, and incidence density for risk of caries of a person (IDp) and of a tooth surface (IDs)...
July 4, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28674702/do-oral-health-educational-programmes-for-expectant-mothers-prevent-early-childhood-caries-%C3%A2-a-systematic-review
#9
Jean Aishwarya Henry, Murugan S Muthu, Kavitha Swaminathan, Richard Kirubakaran
PURPOSE: To summarise the evidence for the efficacy of oral health educational programmes provided to expectant mothers for preventing Early Childhood Caries (ECC) and to determine the most effective intervention programme. MATERIALS AND METHODS: The search strategy included clinical trials in the Cochrane Oral Health Group's Trials Register, PubMed, Science Direct, Google Scholar, LILACS and ClinicalKey (up to 26 August 2013) in English. Reference lists of identified randomised controlled trials (RCTs) and review articles were also hand searched...
2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28667398/caries-progression-as-a-risk-factor-for-increase-in-the-negative-impact-on-ohrqol-a-longitudinal-study
#10
Fabiane Piva, Joanna Tatith Pereira, Patrícia Blaya Luz, Fernando Neves Hugo, Fernando Borba de Araújo
OBJECTIVES: The aim of this study is to evaluate the association between caries lesions progression and oral health-related quality of life (OHRQoL) among Brazilian preschools, after 2 years. MATERIALS AND METHODS: At baseline, 163 children (3-4 years old) enrolled in 12 public primary care services in Porto Alegre/RS-Brazil were evaluated. After 2 years, 119 children were re-evaluated. Calibrated examiners employing the ICDAS criteria conducted clinical examinations...
June 30, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28661802/effectiveness-on-early-childhood-caries-of-an-oral-health-promotion-program-for-medical-providers
#11
Patricia A Braun, Katina Widmer-Racich, Carter Sevick, Erin J Starzyk, Katya Mauritson, Simon J Hambidge
OBJECTIVES: To assess an oral health promotion (OHP) intervention for medical providers' impact on early childhood caries (ECC). METHODS: We implemented a quasiexperimental OHP intervention in 8 federally qualified health centers that trained medical providers on ECC risk assessment, oral examination and instruction, dental referral, and fluoride varnish applications (FVAs). We measured OHP delivery by FVA count at medical visits. We measured the intervention's impact on ECC in 3 unique cohorts of children aged 3 to 4 years in 2009 (preintervention; n = 202), 2011 (midintervention; n = 420), and 2015 (≥ 4 FVAs; n = 153)...
May 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28655504/early-life-factors-and-dental-caries-in-5-year-old-children-in-china
#12
Xiangyu Sun, Eduardo Bernabé, Xuenan Liu, Jennifer E Gallagher, Shuguo Zheng
OBJECTIVES: This study aimed to explore the association between early life factors and dental caries among 5-year-old Chinese children. METHODS: Data from 9,722 preschool children who participated in the third National Oral Health Survey of China were analysed. Information on early life (birth weight, breastfeeding and age when toothbrushing started), child (sex, ethnicity, birth order and dental behaviours) and family factors (parental education, household income, place of residence, number of children in the family, respondent's age and relation to the child) were obtained from parental questionnaires...
June 24, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28643162/dental-caries-a-disease-which-needs-attention
#13
Vijay Prakash Mathur, Jatinder Kaur Dhillon
Dental caries is one of the most prevalent disease (about 50%) in children across the globe. If not treated in time, it can affect not only the mastication function but also the speech, smile and psychosocial environment and the quality of life of the child and the family. The treatment of dental diseases is very expensive in all countries and prevention is very simple and effective. The caries in children below 6 y is called early childhood caries (ECC). It is most commonly caused by milk bottle or mother's feed during night...
June 23, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28642749/rna-seq-reveals-enhanced-sugar-metabolism-in-streptococcus-mutans-co-cultured-with-candida-albicans-within-mixed-species-biofilms
#14
Jinzhi He, Dongyeop Kim, Xuedong Zhou, Sang-Joon Ahn, Robert A Burne, Vincent P Richards, Hyun Koo
Early childhood caries (ECC), which can lead to rampant tooth-decay that is painful and costly to treat, is one of the most prevalent infectious diseases affecting children worldwide. Previous studies support that interactions between Streptococcus mutans and Candida albicans are associated with the pathogenesis of ECC. The presence of Candida enhances S. mutans growth, fitness and accumulation within biofilms in vitro, although the molecular basis for these behaviors is undefined. Using an established co-cultivation biofilm model and RNA-Seq, we investigated how C...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28639687/risk-indicators-of-early-childhood-caries-ecc-in-children-with-high-treatment-needs
#15
Iris Kraljevic, Cornelia Filippi, Andreas Filippi
Early childhood caries (ECC) represents a major health and economic problem worldwide. Its consequences such as early pain experience may affect the immediate and long-term quality of life of the child. In very young and uncooperative children the therapy of ECC is often viable only under general anesthesia. After treatment these affected children have a higher risk for future caries either soon thereafter, or later in life. The aim of the present study was to determine risk indicators and their correlation among children with high caries prevalence and high treatment needs, in order to facilitate the development of targeted prophylaxis programs that would reduce future occurrences of ECC or at least positively influence the outcome...
2017: Swiss Dental Journal
https://www.readbyqxmd.com/read/28631283/assessing-causal-effects-of-early-life-course-factors-on-early-childhood-caries-in-5-year-old-ugandan-children-using-directed-acyclic-graphs-dags-a-prospective-cohort-study
#16
Nancy Birungi, Lars T Fadnes, Arabat Kasangaki, Victoria Nankabirwa, Isaac Okullo, Stein A Lie, James K Tumwine, Anne N Åstrøm
OBJECTIVE: To estimate the effect of distal and proximal early life-course factors on early childhood caries (ECC) in 5-year-old Ugandan children, particularly focusing on the causal effect of exclusive breast feeding (EBF) on ECC using directed acyclic graphs (DAGs) for confounder selection. METHODS: This study had a nested prospective cohort design, focusing on 5 years of follow-ups of caregiver-children pairs from the PROMISE-EBF trial (ClinicalTrials.gov no: NCT00397150) conducted in 2011 in Eastern Uganda...
June 20, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28617874/candida-albicans-mannans-mediate-streptococcus-mutans-exoenzyme-gtfb-binding-to-modulate-cross-kingdom-biofilm-development-in-vivo
#17
Geelsu Hwang, Yuan Liu, Dongyeop Kim, Yong Li, Damian J Krysan, Hyun Koo
Candida albicans is frequently detected with heavy infection by Streptococcus mutans in plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm contains an extensive matrix of extracellular α-glucans that is produced by an exoenzyme (GtfB) secreted by S. mutans. Here, we report that mannans located on the outer surface of C. albicans cell-wall mediates GtfB binding, enhancing glucan-matrix production and modulating bacterial-fungal association within biofilms formed in vivo...
June 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28605597/bacterial-gtfb-augments-candida-albicans-accumulation-in-cross-kingdom-biofilms
#18
K Ellepola, Y Liu, T Cao, H Koo, C J Seneviratne
Streptococcus mutans is a biofilm-forming oral pathogen commonly associated with dental caries. Clinical studies have shown that S. mutans is often detected with Candida albicans in early childhood caries. Although the C. albicans presence has been shown to enhance bacterial accumulation in biofilms, the influence of S. mutans on fungal biology in this mixed-species relationship remains largely uncharacterized. Therefore, we aimed to investigate how the presence of S. mutans influences C. albicans biofilm development and coexistence...
June 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28602851/impact-of-delayed-gratification-on-oral-health-and-caries-status-in-the-primary-dentition
#19
Carolina Caleza-Jimenez, Rosa Yañez-Vico, Asunción Mendoza-Mendoza, Juan Carlos Palma, Alejandro Iglesias-Linares
OBJECTIVE: The ability to delay gratification (ATDG) is naturally linked to key regulatory psychological traits involved in self-discipline/regulation. The aim of this study was to ascertain the normalized impact of ATDG as an early predictor of oral health, on the primary dentition. METHODS: 404 subjects [202 children (4-6 years old) and 202 mothers] were enrolled in a case-control study. Systematic data collection included: i) extraoral diagnostic parameters; ii) intraoral health status; iii) behavioral aspects; iv) baseline socio-demographic data...
June 8, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28584783/association-between-nutritional-status-and-early-childhood-caries-in-indian-children
#20
H V N Sai Krishna, E Manaswini, Vijay Y Kumar, Pavani Bellamkonda, A S Kalyana Bhargava, Ramvilas Reddy Jaidupally
AIMS AND OBJECTIVES: To assess the body mass index (BMI) status and to correlate between nutritional status and early childhood caries among 3-6-year-old children in Vikarabad, Telangana, India. MATERIALS AND METHODS: A cross-sectional study was conducted among 350 children attending the outpatient department of Pedodontia in Sri Sai College of Dental Surgery, Vikarabad. Caries experience was recorded using dmft index (WHO 1997); various anthropometric measures, such as weight, BMI, and height, were recorded as per the standard guidelines...
May 2017: Journal of International Society of Preventive & Community Dentistry
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