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Early childhood caries

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https://www.readbyqxmd.com/read/28643162/dental-caries-a-disease-which-needs-attention
#1
Vijay Prakash Mathur, Jatinder Kaur Dhillon
Dental caries is one of the most prevalent disease (about 50%) in children across the globe. If not treated in time, it can affect not only the mastication function but also the speech, smile and psychosocial environment and the quality of life of the child and the family. The treatment of dental diseases is very expensive in all countries and prevention is very simple and effective. The caries in children below 6 y is called early childhood caries (ECC). It is most commonly caused by milk bottle or mother's feed during night...
June 23, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28642749/rna-seq-reveals-enhanced-sugar-metabolism-in-streptococcus-mutans-co-cultured-with-candida-albicans-within-mixed-species-biofilms
#2
Jinzhi He, Dongyeop Kim, Xuedong Zhou, Sang-Joon Ahn, Robert A Burne, Vincent P Richards, Hyun Koo
Early childhood caries (ECC), which can lead to rampant tooth-decay that is painful and costly to treat, is one of the most prevalent infectious diseases affecting children worldwide. Previous studies support that interactions between Streptococcus mutans and Candida albicans are associated with the pathogenesis of ECC. The presence of Candida enhances S. mutans growth, fitness and accumulation within biofilms in vitro, although the molecular basis for these behaviors is undefined. Using an established co-cultivation biofilm model and RNA-Seq, we investigated how C...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28639687/risk-indicators-of-early-childhood-caries-ecc-in-children-with-high-treatment-needs
#3
Iris Kraljevic, Cornelia Filippi, Andreas Filippi
Early childhood caries (ECC) represents a major health and economic problem worldwide. Its consequences such as early pain experience may affect the immediate and long-term quality of life of the child. In very young and uncooperative children the therapy of ECC is often viable only under general anesthesia. After treatment these affected children have a higher risk for future caries either soon thereafter, or later in life. The aim of the present study was to determine risk indicators and their correlation among children with high caries prevalence and high treatment needs, in order to facilitate the development of targeted prophylaxis programs that would reduce future occurrences of ECC or at least positively influence the outcome...
2017: Swiss Dental Journal
https://www.readbyqxmd.com/read/28631283/assessing-causal-effects-of-early-life-course-factors-on-early-childhood-caries-in-5-year-old-ugandan-children-using-directed-acyclic-graphs-dags-a-prospective-cohort-study
#4
Nancy Birungi, Lars T Fadnes, Arabat Kasangaki, Victoria Nankabirwa, Isaac Okullo, Stein A Lie, James K Tumwine, Anne N Åstrøm
OBJECTIVE: To estimate the effect of distal and proximal early life-course factors on early childhood caries (ECC) in 5-year-old Ugandan children, particularly focusing on the causal effect of exclusive breast feeding (EBF) on ECC using directed acyclic graphs (DAGs) for confounder selection. METHODS: This study had a nested prospective cohort design, focusing on 5 years of follow-ups of caregiver-children pairs from the PROMISE-EBF trial (ClinicalTrials.gov no: NCT00397150) conducted in 2011 in Eastern Uganda...
June 20, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28617874/candida-albicans-mannans-mediate-streptococcus-mutans-exoenzyme-gtfb-binding-to-modulate-cross-kingdom-biofilm-development-in-vivo
#5
Geelsu Hwang, Yuan Liu, Dongyeop Kim, Yong Li, Damian J Krysan, Hyun Koo
Candida albicans is frequently detected with heavy infection by Streptococcus mutans in plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm contains an extensive matrix of extracellular α-glucans that is produced by an exoenzyme (GtfB) secreted by S. mutans. Here, we report that mannans located on the outer surface of C. albicans cell-wall mediates GtfB binding, enhancing glucan-matrix production and modulating bacterial-fungal association within biofilms formed in vivo...
June 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28605597/bacterial-gtfb-augments-candida-albicans-accumulation-in-cross-kingdom-biofilms
#6
K Ellepola, Y Liu, T Cao, H Koo, C J Seneviratne
Streptococcus mutans is a biofilm-forming oral pathogen commonly associated with dental caries. Clinical studies have shown that S. mutans is often detected with Candida albicans in early childhood caries. Although the C. albicans presence has been shown to enhance bacterial accumulation in biofilms, the influence of S. mutans on fungal biology in this mixed-species relationship remains largely uncharacterized. Therefore, we aimed to investigate how the presence of S. mutans influences C. albicans biofilm development and coexistence...
June 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28602851/impact-of-delayed-gratification-on-oral-health-and-caries-status-in-the-primary-dentition
#7
Carolina Caleza-Jimenez, Rosa Yañez-Vico, Asunción Mendoza-Mendoza, Juan Carlos Palma, Alejandro Iglesias-Linares
OBJECTIVE: The ability to delay gratification (ATDG) is naturally linked to key regulatory psychological traits involved in self-discipline/regulation. The aim of this study was to ascertain the normalized impact of ATDG as an early predictor of oral health, on the primary dentition. METHODS: 404 subjects [202 children (4-6 years old) and 202 mothers] were enrolled in a case-control study. Systematic data collection included: i) extraoral diagnostic parameters; ii)intraoral health status; iii)behavioral aspects; iv)baseline socio-demographic data...
June 8, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28584783/association-between-nutritional-status-and-early-childhood-caries-in-indian-children
#8
H V N Sai Krishna, E Manaswini, Vijay Y Kumar, Pavani Bellamkonda, A S Kalyana Bhargava, Ramvilas Reddy Jaidupally
AIMS AND OBJECTIVES: To assess the body mass index (BMI) status and to correlate between nutritional status and early childhood caries among 3-6-year-old children in Vikarabad, Telangana, India. MATERIALS AND METHODS: A cross-sectional study was conducted among 350 children attending the outpatient department of Pedodontia in Sri Sai College of Dental Surgery, Vikarabad. Caries experience was recorded using dmft index (WHO 1997); various anthropometric measures, such as weight, BMI, and height, were recorded as per the standard guidelines...
May 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28579141/diagnostic-potential-of-inflammatory-biomarkers-in-early-childhood-caries-a-case-control-study
#9
Vrinda Sharma, Nidhi Gupta, Nikhil Srivastava, Vivek Rana, Preetika Chandna, Savita Yadav, Alpana Sharma
BACKGROUND: Early Childhood Caries (ECC) is most common chronic infectious disease of childhood. Diagnosis of dental caries has been limited to clinical, visual and radiographic methods but its inflammatory component remained unexplored. Hence, this study aims to evaluate salivary levels of inflammatory cytokines in children with ECC to assess their potential as non-invasive biomarkers. METHODS: 50 subjects were recruited (25 ECC patients and 25 healthy children)...
June 1, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28577641/precision-dentistry-in-early-childhood-the-central-role-of-genomics
#10
REVIEW
Kimon Divaris
Pediatric oral health is determined by the interaction of environmental factors and genetic influences. This is the case for early childhood caries, the most common disease of childhood. The complexity of exogenous-environmental factors interacting with innate biological predispositions results in a continuum of normal variation, as well as oral health and disease outcomes. Optimal oral health and care or precision dentistry warrants comprehensive understanding of these influences and tools enabling intervention on modifiable factors...
July 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28577639/pediatric-dental-focused-interprofessional-interventions-rethinking-early-childhood-oral-health-management
#11
REVIEW
Burton L Edelstein
Evidence of effectiveness for prevention of early childhood caries suggests that parent engagement needs to occur perinatally and that unconventional providers, helping professionals like social workers and dietitians and lay health workers like community health workers, are most effective. This finding, coupled with the emergence of population-based accountable care, value-based purchasing with global payments, understanding of common risk factors for multiple conditions, and social determinants of health behaviors, calls for a rethinking of early childhood oral health care...
July 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28573263/risk-factors-associated-with-early-childhood-caries
#12
Hui Bin Sun, Wei Zhang, Xiao Bin Zhou
OBJECTIVE: To analyse factors associated with the susceptibility of early childhood caries (ECC), populations with a high risk of ECC were screened and guidance for ECC prevention was proposed. METHODS: A total of 392 children aged 24 to 71 months were selected for oral examination in Qingdao. Parents or guardians of the participants completed the questionnaires and decayed missing filled surface (dmfs) were recorded. Differences in caries condition and oral health behaviour in different families were compared...
2017: Chinese Journal of Dental Research
https://www.readbyqxmd.com/read/28561556/association-between-sense-of-coherence-and-oral-health-related-quality-of-life-among-toddlers
#13
I B Fernandes, D C Costa, V S Coelho, A C Sá-Pinto, J Ramos-Jorge, M L Ramos-Jorge
Objective: To assess the relationship between sense of coherence (SOC) and oral health-related quality of life (OHRQoL) among children aged one to three years. Participants: A cross-sectional study was conducted with 276 mother-child pairs randomly selected from the city of Diamantina, Brazil. Method: Information was obtained on socio-demographic factors. The short version of Antonovsky's sense of coherence scale (SOC 13) and the Early Childhood Oral Health Impact Scale (ECOHIS) were administered...
March 2017: Community Dental Health
https://www.readbyqxmd.com/read/28547864/sociodemographic-determinants-of-spatial-disparities-in-early-childhood-caries-an-ecological-analysis-in-braunschweig-germany
#14
Frederic Meyer, André Karch, Kristin Maria Schlinkmann, Johannes Dreesman, Johannes Horn, Nicole Rübsamen, Henny Sudradjat, Rainer Schubert, Rafael Mikolajczyk
OBJECTIVES: To identify spatial disparities in dental caries experience (measured by dmft (decayed missing filled teeth) index) of children in the city of Braunschweig and to evaluate whether these disparities can be explained by sociodemographic characteristics. METHODS: We examined the dental health of children aged 3-6 years visiting a daycare centre (DCC) in the metropolitan area of Braunschweig between 2009 and 2014 by combining data on dental health from the annual visits of the local health service with aggregated data on sociodemographic factors for Braunschweig's city districts...
May 26, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28540394/clinical-efficacy-of-a-two-year-oral-health-programme-for-infants-and-toddlers-in-singapore
#15
Bien Lai, Wee Kiat Tan, Qing Shu Lu
INTRODUCTION: Dental caries, which is prevalent in Singapore preschoolers, is a disease that has a major impact on children's health and places a high cost on the society and health services. Oral health programmes for young children implemented in several parts of the world have been shown to be effective in the prevention of dental caries. We aimed to examine the clinical efficacy of an oral health programme for infants and toddlers in Singapore. METHODS: 90 children and their caregivers participated in the programme while 64 children who were 24 months older than the intervention group at initial visit were recruited as controls in a quasi-experimental study design...
May 25, 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28538220/identification-of-caries-risk-determinants-in-toddlers-results-of-the-gusto-birth-cohort-study
#16
C Un Lam, L W Khin, A C Kalhan, R Yee, Y S Lee, M F-F Chong, K Kwek, S M Saw, K Godfrey, Y S Chong, C-Y Hsu
The aim of this study was to identify risk determinants leading to early childhood caries (ECC) and visible plaque (VP) in toddlers. Data for mother-child pairs participating in the Growing Up in Singapore towards Healthy Outcomes (GUSTO) birth cohort were collected from pregnancy to toddlerhood. Oral examinations were performed in 543 children during their clinic visit at 24 months to detect ECC and VP. Following logistic regression, ECC and VP were jointly regressed as primary and secondary outcomes, respectively, using the bivariate probit model...
May 25, 2017: Caries Research
https://www.readbyqxmd.com/read/28531148/early-childhood-dental-caries-mouth-pain-and-malnutrition-in-the-ecuadorian-amazon-region
#17
Marvin So, Yianni A Ellenikiotis, Hannah M Husby, Cecilia Leonor Paz, Brittany Seymour, Karen Sokal-Gutierrez
Malnutrition and dental caries in early childhood remain persistent and intertwined global health challenges, particularly for indigenous and geographically-remote populations. To examine the prevalence and associations between early childhood dental caries, parent-reported mouth pain and malnutrition in the Amazonian region of Ecuador, we conducted a cross-sectional study of the oral health and nutrition status of 1407 children from birth through age 6 in the "Alli Kiru" program (2011-2013). We used multivariate regression analysis to examine relationships between severe caries, parent-reported mouth pain measures, and nutritional status...
May 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28526003/the-basic-research-factors-questionnaire-for-studying-early-childhood-caries
#18
Judith Albino, Tamanna Tiwari, Stuart A Gansky, Michelle M Henshaw, Judith C Barker, Angela G Brega, Steven E Gregorich, Brenda Heaton, Terrence S Batliner, Belinda Borrelli, Paul Geltman, Nancy R Kressin, Jane A Weintraub, Tracy L Finlayson, Raul I Garcia
BACKGROUND: We describe development of the Early Childhood Caries (ECC) Basic Research Factors Questionnaire (BRFQ), a battery of measures assessing common potential predictors, mediators, and moderators of ECC. Individual-, family-, and community-level factors that are linked to oral health outcomes across at-risk populations are included. Developing standard measures of factors implicated in ECC has the potential to enhance our ability to understand mechanisms underlying successful prevention and to develop more effective interventions...
May 19, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28514517/early-childhood-caries-and-psychological-perceptions-on-child-s-oral-health-increase-the-feeling-of-guilt-in-parents-an-epidemiological-survey
#19
Thiago Saads Carvalho, Jenny Abanto, Elayne Cristina Morais Pinheiro, Adrian Lussi, Marcelo Bönecker
AIM: To assess whether parents feel guilty for their children's oral problems, associating this feeling with socio-economic, demographic, and psychological factors. DESIGN: We included 1313 parent-and-child pairs in this study. The children were 2-4 years old. Parents answered questionnaires on socio-economic and demographic data, and on psychological variables. Sixteen trained dentists (κ > 0.8) examined the children for oral hygiene (the presence and absence of plaque), early childhood caries (ECC; no caries, low and high severity), malocclusion (the presence and absence), and traumatic dental injuries (TDI; the presence and absence)...
May 17, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28492756/a-longitudinal-study-of-early-childhood-caries-and-associated-factors-in-brazilian-children
#20
Fabiane Piva, Joanna Tatith Pereira, Patrícia Blaya Luz, Lina Naomi Hashizume, Fernando Neves Hugo, Fernando Borba de Araujo
Early childhood caries (ECC) affects children all over the world and has high prevalence and severity in preschool children. Different social, biological and behavioral factors compose a network of causal factors for ECC. The aim was to evaluate the association between socioeconomic variables and caries at baseline, and the presence of Streptococcus mutans and Lactobacillus spp. microorganisms with the progression of caries lesions after two years of follow-up in a group of children. At baseline, 163 children (3-4 years old) living in the areas of 12 primary care services of the Hospital Group Conceição (GHC, Porto Alegre, RS, Brazil) were evaluated...
March 2017: Brazilian Dental Journal
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