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https://www.readbyqxmd.com/read/29444207/the-functional-network-signature-of-heterogeneity-in-freezing-of-gait
#1
Kaylena A Ehgoetz Martens, Julie M Hall, Matthew J Georgiades, Moran Gilat, Courtney C Walton, Elie Matar, Simon J G Lewis, James M Shine
Freezing of gait is a complex, heterogeneous, and highly variable phenomenon whose pathophysiology and neural signature remains enigmatic. Evidence suggests that freezing is associated with impairments across cognitive, motor and affective domains; however, most research to date has focused on investigating one axis of freezing of gait in isolation. This has led to inconsistent findings and a range of different pathophysiological models of freezing of gait, due in large part to the tendency for studies to investigate freezing of gait as a homogeneous entity...
February 9, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29443918/error-modelling-for-multi-sensor-measurements-in-infrastructure-free-indoor-navigation
#2
Laura Ruotsalainen, Martti Kirkko-Jaakkola, Jesperi Rantanen, Maija Mäkelä
The long-term objective of our research is to develop a method for infrastructure-free simultaneous localization and mapping (SLAM) and context recognition for tactical situational awareness. Localization will be realized by propagating motion measurements obtained using a monocular camera, a foot-mounted Inertial Measurement Unit (IMU), sonar, and a barometer. Due to the size and weight requirements set by tactical applications, Micro-Electro-Mechanical (MEMS) sensors will be used. However, MEMS sensors suffer from biases and drift errors that may substantially decrease the position accuracy...
February 14, 2018: Sensors
https://www.readbyqxmd.com/read/29443831/assessment-of-the-effect-of-autograft-orientation-on-peripheral-nerve-regeneration-using-diffusion-tensor-imaging
#3
Ashkan Afshari, Lyly Nguyen, Nathaniel D Kelm, Justine S Kim, Nancy L Cardwell, Alonda C Pollins, Ravinder Bamba, R Bruce Shack, Mark D Does, Wesley P Thayer
PURPOSE: Given no definite consensus on the accepted autograft orientation during peripheral nerve injury repair, we compare outcomes between reverse and normally oriented autografts using an advanced magnetic resonance imaging technique, diffusion tensor imaging. METHODS: Thirty-six female Sprague-Dawley rats were divided into 3 groups: sham-left sciatic nerve isolation without injury, reverse autograft-10-mm cut left sciatic nerve segment reoriented 180° and used to coapt the proximal and distal stumps, or normally oriented autograft-10-mm cut nerve segment kept in its normal orientation for coaptation...
February 13, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29441642/lycra-splinting-garments-for-adults-with-intellectual-disabilities-who-fall-due-to-gait-or-balance-issues-a-feasibility-study
#4
J Finlayson, J Crockett, S Shanmugam, B Stansfield
BACKGROUND: Adults with intellectual disabilities (IDs) experience high rates of falls and have high rates of gait or balance issues which contribute to falls. Lycra splinting garments (LSGs) have potential to improve gait or balance, but they have never before been tested with adults with IDs who fall due to gait or balance issues. The aim of this study was to test in adults with IDs, the feasibility of using LSGs to improve movement and function and reduce falls, whilst also exploring usability and likely compliance...
February 14, 2018: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29437636/outcomes-following-limb-salvage-after-combat-hindfoot-injury-are-inferior-to-delayed-amputation-at-five-years
#5
P M Bennett, T Stevenson, I D Sargeant, A Mountain, J G Penn-Barwell
OBJECTIVES: The surgical challenge with severe hindfoot injuries is one of technical feasibility, and whether the limb can be salvaged. There is an additional question of whether these injuries should be managed with limb salvage, or whether patients would achieve a greater quality of life with a transtibial amputation. This study aims to measure functional outcomes in military patients sustaining hindfoot fractures, and identify injury features associated with poor function. METHODS: Follow-up was attempted in all United Kingdom military casualties sustaining hindfoot fractures...
February 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29437061/mid-term-follow-up-of-patients-with-hindfoot-arthrodesis-with-retrograde-compression-intramedullary-nail-in-charcot-neuroarthropathy-of-the-hindfoot
#6
M Chraim, S Krenn, H M Alrabai, H-J Trnka, P Bock
AIMS: Hindfoot arthrodesis with retrograde intramedullary nailing has been described as a surgical strategy to reconstruct deformities of the ankle and hindfoot in patients with Charcot arthropathy. This study presents case series of Charcot arthropathy patients treated with two different retrograde intramedullary straight compression nails in order to reconstruct the hindfoot and assess the results over a mid-term follow-up. PATIENTS AND METHODS: We performed a retrospective analysis of 18 consecutive patients and 19 operated feet with Charcot arthropathy who underwent a hindfoot arthrodesis using a retrograde intramedullary compression nail...
February 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29437059/a-new-and-reliable-classification-system-for-fractures-of-the-navicular-and-associated-injuries-to-the-midfoot
#7
M J Petrie, C M Blakey, C Chadwick, H G Davies, C M Blundell, M B Davies
AIMS: Fractures of the navicular can occur in isolation but, owing to the intimate anatomical and biomechanical relationships, are often associated with other injuries to the neighbouring bones and joints in the foot. As a result, they can lead to long-term morbidity and poor function. Our aim in this study was to identify patterns of injury in a new classification system of traumatic fractures of the navicular, with consideration being given to the commonly associated injuries to the midfoot...
February 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29436477/combat-related-foot-injuries-impact-on-gait-and-functional-outcome
#8
Loes G M de Kruijff, M Prins, A van der Krans, R Hoencamp, P van der Wurff
INTRODUCTION: Prior to deployment of the Netherlands Army Task Force Urozgan in Afghanistan, the Dutch Military and civilian healthcare systems had limited experience in treating blast injuries and their long-term consequences. This meant that guidelines for treatment and rehabilitation were lacking. The aim of this cohort study was to quantify kinematic and kinetic abnormalities in service members with foot injuries in relation to functional outcome using gait analysis. METHOD: In nine service members with combat-related talus, calcaneus and/or navicular bone (TCN) fractures and nine controls, gait parameters were measured using Gait Real-Time Analysis Interactive Lab system...
February 7, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29436233/intratissue-percutaneous-electrolysis-vs-corticosteroid-infiltration-for-the-treatment-of-plantar-fasciosis
#9
Álvaro Iborra-Marcos, Juan José Ramos-Álvarez, Guillermo Rodriguez-Fabián, Federico Del Castillo-González, Antonio López-Román, Carlos Polo-Portes, Manuel Villanueva-Martínez
BACKGROUND: Corticosteroid infiltration (CI) is commonly used for treatment of plantar fasciosis. In recent years, however, interest has grown in the use of intratissue percutaneous electrolysis (EPI) for the treatment of tendinopathies. The aim of our study was to compare the effectiveness of the above techniques in the treatment of plantar fasciosis. METHODS: The results achieved over a period of 1 year following the use of these techniques to treat plantar fasciosis were examined...
February 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29432112/the-development-and-preliminary-test-of-a-powered-alternately-walking-exoskeleton-with-the-wheeled-foot-for-paraplegic-patients
#10
Qingchuan Ma, Linhong Ji, Rencheng Wang
Upright walking has both physical and social meanings for paraplegic patients. The main purpose of this paper is to reduce the automatic functioning of the powered exoskeleton and enable the user to fully control the walking procedure in real-time, aiming to further improve the engagement of the patient during rehabilitation training. For this prototype, a custom-made hub motor was placed at the bottom of the exoskeleton's foot, and a pair of crutches with the embedded wireless controller were utilized as the auxiliary device...
February 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29430642/should-structured-exercise-be-promoted-as-a-model-of-care-dissemination-of-the-department-of-veterans-affairs-gerofit-program
#11
Miriam C Morey, Cathy C Lee, Steven Castle, Willy M Valencia, Leslie Katzel, Jamie Giffuni, Teresa Kopp, Heather Cammarata, Michelle McDonald, Kris A Oursler, Timothy Wamsley, Chani Jain, Janet P Bettger, Megan Pearson, Kenneth M Manning, Orna Intrator, Peter Veazie, Richard Sloane, Jiejin Li, Daniel C Parker
Exercise provides a wide range of health-promoting benefits, but support is limited for clinical programs that use exercise as a means of health promotion. This stands in contrast to restorative or rehabilitative exercise, which is considered an essential medical service. We propose that there is a place for ongoing, structured wellness and health promotion programs, with exercise as the primary therapeutic focus. Such programs have long-lasting health benefits, are easily implementable, and are associated with high levels of participant satisfaction...
February 12, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29428686/reconstruction-of-a-complex-foot-injury-with-free-remodeled-fibular-osteocutaneous-flap-a-case-report-and-literature-review
#12
Liangsong Song, Zhixin Zhang, Yang Wang, Yang Liu, Zhigang Liu, Lei Chen, Laijin Lu
Management of complex foot injuries, which involve open fractures and severe trauma to soft tissues, represent a challenge to orthopedic clinicians. In the present case report, we treated a complex foot injury with a remodeled fibular osteocutaneous free flap to reconstruct the anterior and lateral areas of the foot. The flap survived completely. At the 9-month follow-up examination, bony union of the graft bone was identified by radiographic examination. The reconstructed foot could bear body weight, and the patient could maintain a bipedal gait without discomfort...
February 8, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29427788/split-hand-foot-malformation-and-a-novel-wnt10b-mutation
#13
Piranit Nik Kantaputra, Seema Kapoor, Prashant Verma, Worrachet Intachai, James R Ketudat Cairns
We report an Indian girl with split-hand/foot malformation (SHFM), sparse hair, and interrupted eyebrows, who carries a novel homozygous deletion c.695_697delACA in WNT10B. The variant is deduced to cause an in-frame deletion of Asn residue 232 (p.Asn232del). According to the protein model, this single amino acid deletion at the critical position in the protein structure is likely to severely affect the protein structure and function. This deletion is likely to lead decreased lifetime and make it unable to bind to its receptors and other ligands...
February 7, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29421837/all-inside-single-bundle-reconstruction-of-the-anterior-cruciate-ligament-with-the-anterior-half-of-the-peroneus-longus-tendon-compared-to-the-semitendinosus-tendon-a-two-year-follow-up-study
#14
Mingguang Bi, Chen Zhao, Shuijun Zhang, Bin Yao, Zheping Hong, Qing Bi
The anterior half of the peroneus longus tendon (AHPLT) has been reported to be acceptable for ligament reconstruction with respect to strength and safety. However, there is little information regarding the clinical outcomes after using the AHPLT compared with other autograft tendons. A prospective randomized controlled study was performed to compare the results of 62 cases of all-inside anatomical single-bundle anterior cruciate ligament (ACL) reconstruction using the AHPLT and 62 cases using semitendinosus graft with an average of 30...
February 8, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29421811/swiprosin-1-promotes-mitochondria-dependent-apoptosis-of-glomerular-podocytes-via-p38-mapk-pathway-in-early-stage-diabetic-nephropathy
#15
Rong-Mei Wang, Zhi-Bin Wang, Yue Wang, Wei-Ye Liu, Ya Li, Ling-Chang Tong, Su Zhang, Ding-Feng Su, Yong-Bing Cao, Ling Li, Li-Chao Zhang
BACKGROUND/AIMS: Podocyte injury, especially podocyte apoptosis, plays a major role in early-stage diabetic nephropathy (DN). Swiprosin-1, also known as EF hand domain containing 2 (EFhd2), is a Ca2+-binding protein in different cell types. However, the function of swiprosin-1 in podocytes remains unknown. METHODS: The expression and distribution of swiprosin-1 were investigated in the mouse renal glomerulus and conditionally immortalized mouse podocyte cell line MPC-5...
February 2, 2018: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29420055/functional-results-of-open-brostr%C3%A3-m-ankle-ligament-repair-augmented-with-a-suture-tape
#16
J Chris Coetzee, J Kent Ellington, James A Ronan, Rebecca M Stone
BACKGROUND: The Broström procedure is the most commonly used lateral ligament repair for chronic instability, but there is concern about the strength of the repair and the risk of reinjury. Currently, the InternalBraceTM ligament augmentation repair is an accepted augmentation method for management of a Broström procedure. Our hypothesis was that augmentation of the Broström repair with an InternalBraceTM would allow accelerated rehabilitation and return to activity and would aid in stability of the repair without a tendency to stretch...
February 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29417781/-surgical-treatment-for-talar-neck-fracture-of-hawkins-iii-iv-type-with-compression-hollow-screws-combined-with-external-fixator
#17
Xian-Xun Wang, Chang-Tao Wan, Li Yu
OBJECTIVE: To investigate the clinical effects of compression hollow screws combined with external fixator in treating talar neck fracture of Hawkins III, IV type. METHODS: From March 2010 to August 2014, 15 patients with talar neck fractures of Hawkins III, IV type were treated by open reduction and compression hollow screws fixation complicated with external fixator fixation. Including 9 males and 6 females, aged from 17 to 65 years old with an average of 37.5 years old...
May 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29417017/how-much-do-persons-with-diabetes-in-a-rural-area-of-south-india-know-about-diabetes-management-a-step-toward-person-centered-care
#18
Marie Gilbert Majella, Palanivel Chinnakali, Bijay Nanda Naik, Pruthu Thekkur, Bharath Nag, Gomathi Ramaswamy
Introduction: The burden of diabetes mellitus is increasing worldwide, more so in developing countries. Optimal diabetes care depends on adherence to management protocol, which can be brought about by shared decision-making. Patient's knowledge on life-threatening complications and preventive strategies for the same is a prerequisite for shared decision-making. Hence, this study was carried out among diabetes patients to assess the level of knowledge on different aspects of diabetes management...
July 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29414988/laboratory-and-community-based-health-outcomes-in-people-with-transtibial-amputation-using-crossover-and-energy-storing-prosthetic-feet-a-randomized-crossover-trial
#19
Sara J Morgan, Cody L McDonald, Elizabeth G Halsne, Sarah M Cheever, Rana Salem, Patricia A Kramer, Brian J Hafner
Contemporary prosthetic feet are generally optimized for either daily or high-level activities. Prosthesis users, therefore, often require multiple prostheses to participate in activities that span a range of mobility. Crossover feet (XF) are designed to increase the range of activities that can be performed with a single prosthesis. However, little evidence exists to guide clinical prescription of XF relative to traditional energy storing feet (ESF). The objective of this study was to assess the effects of XF and ESF on health outcomes in people with transtibial amputation...
2018: PloS One
https://www.readbyqxmd.com/read/29414290/correlation-between-the-corpus-callosum-index-and-brain-atrophy-lesion-load-and-cognitive-dysfunction-in-multiple-sclerosis
#20
Lucas Immich Gonçalves, Giordani Rodrigues Dos Passos, Lucas Piccoli Conzatti, Jorge Luiz Palmeiro Burger, Gustavo Henrique Tomasi, Manuella Édler Zandoná, Luciana Schermann Azambuja, Irênio Gomes, Alexandre Franco, Douglas Kazutoshi Sato, Jefferson Becker
BACKGROUND: The corpus callosum index (CCI) can be easily and reliably obtained from conventional magnetic resonance imaging (MRI) and has been proposed as a possible marker of brain atrophy in MS. However, further validation of its correlation with volumetric measurements is still warranted. OBJECTIVE: To assess the correlation of the CCI with the corpus callosum volume (CCV), brain and lesion volumes, and level of disability in MS. METHODS: Cross-sectional, exploratory study including patients with relapsing-remitting MS...
January 26, 2018: Multiple Sclerosis and related Disorders
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