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https://www.readbyqxmd.com/read/29470505/grunting-s-competitive-advantage-considerations-of-force-and-distraction
#1
Scott Sinnett, Cj Maglinti, Alan Kingstone
BACKGROUND: Grunting is pervasive in many athletic contests, and empirical evidence suggests that it may result in one exerting more physical force. It may also distract one's opponent. That grunts can distract was supported by a study showing that it led to an opponent being slower and more error prone when viewing tennis shots. An alternative explanation was that grunting masks the sound of a ball being hit. The present study provides evidence against this alternative explanation by testing the effect of grunting in a sport-mixed martial arts-where distraction, rather than masking, is the most likely mechanism...
2018: PloS One
https://www.readbyqxmd.com/read/29466679/a-biomechanical-comparison-of-fifth-metatarsal-jones-fracture-fixation-methods
#2
Neil L Duplantier, Ronald J Mitchell, Steve Zambrano, Aaron C Stone, Domenica A Delgado, Bradley S Lambert, Michael R Moreno, Joshua D Harris, Patrick C McCulloch, David M Lintner, Kevin E Varner
BACKGROUND: Fifth metatarsal base fractures of the metaphyseal-diaphyseal watershed junction (Jones fracture) are commonly treated with surgical fixation in athletes. Intramedullary screw fixation remains the most utilized construct, although plantar-lateral plating is an alternative. Purpose/Hypothesis: The purpose was to compare the mechanical strength of fracture fixation between an intramedullary screw and plantar-lateral plating. The hypothesis was that plantar-lateral plate fixation would allow for more cycles and higher peak loads before failure, as well as less fracture gapping, than would an intramedullary screw in cadaveric foot specimens with simulated Jones fractures exposed to cantilever bending...
February 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29466019/video-analysis-of-anterior-cruciate-ligament-tears-in-professional-american-football-athletes
#3
Jeffrey T Johnston, Bert R Mandelbaum, David Schub, Scott A Rodeo, Matthew J Matava, Holly J Silvers, Brian J Cole, Neil S ElAttrache, Tim R McAdams, Robert H Brophy
BACKGROUND: Anterior cruciate ligament (ACL) injuries are prevalent in contact sports that feature cutting and pivoting, such as American football. These injuries typically require surgical treatment, can result in significant missed time from competition, and may have deleterious long-term effects on an athlete's playing career and health. While the majority of ACL tears in other sports have been shown to occur from a noncontact mechanism, it stands to reason that a significant number of ACL tears in American football would occur after contact, given the nature of the sport...
February 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29465432/mechanisms-for-lesion-localization-in-neuromyelitis-optica-spectrum-disorders
#4
Monika Bradl, Markus Reindl, Hans Lassmann
PURPOSE OF REVIEW: Neuromyelitis optica spectrum disorders (NMOSD) are severe inflammatory diseases of the central nervous system (CNS), with the presence of aquaporin 4 (AQP4)-specific serum antibodies in the vast majority of patients, and with the presence of myelin oligodendrocyte glycoprotein (MOG)-specific antibodies in approximately 40% of all AQP4-antibody negative NMOSD patients. Despite differences in antigen recognition, the preferred sites of lesions are similar in both groups of patients: They localize to the spinal cord and to the anterior visual pathway including retina, optic nerves, chiasm, and optic tracts, and - to lesser extent - also to certain predilection sites in the brain...
February 20, 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29464408/isolation-and-identification-of-bovine-nasopharyngeal-mucosal-epithelial-cells-and-establishment-of-cell-models-of-acute-infection-by-foot-and-mouth-disease-virus
#5
Wan-Fu Bai, Lu Li, Ting Zhang, Xiao-Hu Su, Yong-Wei Wang, Bing-Wu Zhao, Tao Zhang, Huan-Min Zhou
Foot-and-mouth disease (FMD) commonly occurs via the respiratory tract, and bovine nasopharyngeal mucosal epithelial cells are the primary infection cells in cattle. The aim of the present study was to isolate and culture epithelial cells from the bovine nasopharyngeal mucosa in vitro using a mechanical separation method. The cells were expanded, established in continuous cell culture, and used for immunofluorescence cytochemistry and establishment of infection models. We detected pan-cytokeratin markers of bovine nasopharyngeal mucosal epithelial cells by immunofluorescence...
February 20, 2018: In Vitro Cellular & Developmental Biology. Animal
https://www.readbyqxmd.com/read/29460747/epidemiology-of-recurrent-hand-foot-and-mouth-disease-china-2008-2015
#6
Jiao Huang, Qiaohong Liao, Mong How Ooi, Benjamin J Cowling, Zhaorui Chang, Peng Wu, Fengfeng Liu, Yu Li, Li Luo, Shuanbao Yu, Hongjie Yu, Sheng Wei
Using China's national surveillance data on hand, foot and mouth disease (HFMD) for 2008-2015, we described the epidemiologic and virologic features of recurrent HFMD. A total of 398,010 patients had HFMD recurrence; 1,767 patients had 1,814 cases of recurrent laboratory-confirmed HFMD: 99 reinfections of enterovirus A71 (EV-A71) with EV-A71, 45 of coxsackievirus A16 (CV-A16) with CV-A16, 364 of other enteroviruses with other enteroviruses, 383 of EV-A71 with CV-A16 and CV-A16 with EV-A71, and 923 of EV-A71 or CV-A16 with other enteroviruses and other enteroviruses with EV-A71 or CV-A16...
March 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29456169/kinematics-of-lower-limbs-during-walking-are-emulated-by-springy-walking-model-with-a-compliantly-connected-off-centered-curvy-foot
#7
Hyerim Lim, Sukyung Park
The dynamics of the center of mass (CoM) during walking and running at various gait conditions are well described by the mechanics of a simple passive spring loaded inverted pendulum (SLIP). Due to its simplicity, however, the current form of the SLIP model is limited at providing any further information about multi-segmental lower limbs that generate oscillatory CoM behaviors and their corresponding ground reaction forces. Considering that the dynamics of the CoM are simply achieved by mass-spring mechanics, we wondered whether any of the multi-joint motions could be demonstrated by simple mechanics...
February 8, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29455065/foot-and-mouth-disease-virus-type-o-specific-mutations-determine-rna-dependent-rna-polymerase-fidelity-and-virus-attenuation
#8
Chen Li, Haiwei Wang, Tiangang Yuan, Andrew Woodman, Decheng Yang, Guohui Zhou, Craig E Cameron, Li Yu
Previous studies have shown that the FMDV Asia1/YS/CHA/05 high-fidelity mutagen-resistant variants are attenuated (Zeng et al., 2014). Here, we introduced the same single or multiple-amino-acid substitutions responsible for increased 3Dpol fidelity of type Asia1 FMDV into the type O FMDV O/YS/CHA/05 infectious clone. The rescued viruses O-DA and O-DAMM are lower replication fidelity mutants and showed an attenuated phenotype. These results demonstrated that the same amino acid substitution of 3Dpol in different serotypes of FMDV strains had different effects on viral fidelity...
February 15, 2018: Virology
https://www.readbyqxmd.com/read/29451922/identifying-classifier-input-signals-to-predict-a-cross-slope-during-transtibial-amputee-walking
#9
Courtney E Shell, Glenn K Klute, Richard R Neptune
Advanced prosthetic foot designs often incorporate mechanisms that adapt to terrain changes in real-time to improve mobility. Early identification of terrain (e.g., cross-slopes) is critical to appropriate adaptation. This study suggests that a simple classifier based on linear discriminant analysis can accurately predict a cross-slope encountered (0°, -15°, 15°) using measurements from the residual limb, primarily from the prosthesis itself. The classifier was trained and tested offline using motion capture and in-pylon sensor data collected during walking trials in mid-swing and early stance...
2018: PloS One
https://www.readbyqxmd.com/read/29450562/-which-typical-foot-fractures-should-the-radiologist-know
#10
REVIEW
G Bratke, V Neuhaus, K Slebocki, S Haneder, R Rau
CLINICAL/METHODICAL ISSUE: Due to mechanical loading and the number of joints involved, fractures of the foot are among the most common fractures. STANDARD RADIOLOGICAL METHODS: X-ray is basis for diagnostic workup of all foot fractures. METHODICAL INNOVATIONS: For stress fractures, the additional use of magnetic resonance imaging (MRI) is indicated. Computed tomography (CT) can be used for preoperative imaging of intraarticular tarsal fractures...
February 15, 2018: Der Radiologe
https://www.readbyqxmd.com/read/29447975/profiling-of-novel-micrornas-elicited-by-ev71-and-ca16-infection-in-human-bronchial-epithelial-cells-using-high-throughput-sequencing
#11
Jie Song, Yajie Hu, Xi Jiang, Wenbing Zhu, Zhongxiang Wu, Shaozhong Dong
Enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are two major etiologic agents associated with hand, foot, and mouth disease (HFMD) worldwide. Despite that they both belong to the Enterovirus genus of the Picornaviridae family, there are many differences in the infection process of these viruses. However, the underlying mechanisms have not been elucidated. Multiple studies indicated that microRNAs (miRNAs) can play critical roles in the host-pathogen interaction. Our previous study reported that EV71 and CA16 infection leads to differential expression of miRNAs in human bronchial epithelial (16HBE) cells...
February 12, 2018: Virus Research
https://www.readbyqxmd.com/read/29447194/vitro-culture-of-axe-head-glochidia-in-pink-heelsplitter-potamilus-alatus-and-mechanism-of-its-high-host-specialists
#12
Hai Bo Wen, Wu Jin, Xue Yan Ma, Bing Qing Zheng, Pao Xu, Liang Xu, Dan Hua, Xin Hua Yuan, Ruo Bo Gu
The basal media M199 or MEM was utilized in the classical method of vitro culture of glochidia where 1-5% CO2 was required to maintain stable physiological pH for completion of non-parasitic metamorphosis. The classical method encounters a great challenge to those glochidia which undergo development of visceral tissue but significantly increase in size during metamorphosis. The improved in vitro culture techniques and classical methods were firstly compared for non-parasitic metamorphosis and development of glochidia in pink heelsplitter...
2018: PloS One
https://www.readbyqxmd.com/read/29447180/experimental-research-on-the-structural-instability-mechanism-and-the-effect-of-multi-echelon-support-of-deep-roadways-in-a-kilometre-deep-well
#13
Rui Peng, Xiangrui Meng, Guangming Zhao, Yingming Li, Jianming Zhu
We study the structural instability mechanism and effect of a multi-echelon support in very-deep roadways. We conduct a scale model test for analysing the structural failure mechanism and the effect of multi-echelon support of roadways under high horizontal stress. Mechanical bearing structures are classified according to their secondary stress distribution and the strength degradation of the surrounding rock after roadway excavation. A new method is proposed by partitioning the mechanical bearing structure of the surrounding rock into weak, key and main coupling bearing stratums...
2018: PloS One
https://www.readbyqxmd.com/read/29444939/single-cell-analysis-of-the-impact-of-host-cell-heterogeneity-on-infection-with-foot-and-mouth-disease-virus
#14
Xiu Xin, Hailong Wang, Lingling Han, Mingzhen Wang, Hui Fang, Yao Hao, Jiadai Li, Hu Zhang, Congyi Zheng, Chao Shen
Viral infection and replication are affected by host-cell heterogeneity, but the mechanisms underlying the effects remain unclear. Using single-cell analysis, we investigated the effects of host-cell heterogeneity, including cell size, inclusion, and cell cycle, on foot and mouth disease virus (FMDV) infection (acute and persistent infections) and replication. We detected variable viral genome replication levels in FMDV-infected cells. Larger cells and cells with a greater number of inclusions generated more viral RNA copies, viral protein, and a higher proportion of infectious cells...
February 14, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29444207/the-functional-network-signature-of-heterogeneity-in-freezing-of-gait
#15
Kaylena A Ehgoetz Martens, Julie M Hall, Matthew J Georgiades, Moran Gilat, Courtney C Walton, Elie Matar, Simon J G Lewis, James M Shine
Freezing of gait is a complex, heterogeneous, and highly variable phenomenon whose pathophysiology and neural signature remains enigmatic. Evidence suggests that freezing is associated with impairments across cognitive, motor and affective domains; however, most research to date has focused on investigating one axis of freezing of gait in isolation. This has led to inconsistent findings and a range of different pathophysiological models of freezing of gait, due in large part to the tendency for studies to investigate freezing of gait as a homogeneous entity...
February 9, 2018: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29443918/error-modelling-for-multi-sensor-measurements-in-infrastructure-free-indoor-navigation
#16
Laura Ruotsalainen, Martti Kirkko-Jaakkola, Jesperi Rantanen, Maija Mäkelä
The long-term objective of our research is to develop a method for infrastructure-free simultaneous localization and mapping (SLAM) and context recognition for tactical situational awareness. Localization will be realized by propagating motion measurements obtained using a monocular camera, a foot-mounted Inertial Measurement Unit (IMU), sonar, and a barometer. Due to the size and weight requirements set by tactical applications, Micro-Electro-Mechanical (MEMS) sensors will be used. However, MEMS sensors suffer from biases and drift errors that may substantially decrease the position accuracy...
February 14, 2018: Sensors
https://www.readbyqxmd.com/read/29443819/chronic-osteomyelitis-with-staphylococcus-aureus-deformation-in-submicron-canaliculi-of-osteocytes-a-case-report
#17
Karen L de Mesy Bentley, Ashlee MacDonald, Edward M Schwarz, Irvin Oh
CASE: A patient presenting with an infected diabetic foot ulcer and Staphylococcus aureus chronic osteomyelitis was studied to validate the clinical importance of bacterial colonization of osteocytic-canalicular networks, as we recently reported in a mouse model. We utilized transmission electron microscopy to describe the deformation of S. aureus, from round cocci to rod-shaped bacteria, in the submicron osteocytic-canalicular networks of amputated bone tissue. CONCLUSION: To our knowledge, this is the first evidence of S...
February 14, 2018: JBJS Case Connector
https://www.readbyqxmd.com/read/29441131/centre-of-pressure-characteristics-in-normal-planus-and-cavus-feet
#18
Andrew K Buldt, Saeed Forghany, Karl B Landorf, George S Murley, Pazit Levinger, Hylton B Menz
Background: The aim of this study was to compare centre of pressure (COP) characteristics between healthy adults with normal, planus or cavus feet who were allocated to groups based on reliable foot posture measurement techniques. Methods: Ninety-two healthy adult participants (aged 18 to 45) were recruited and classified as either normal ( n = 35), pes planus ( n = 31) or pes cavus ( n = 26) based on Foot Posture Index, Arch Index and normalised navicular height truncated measurements...
2018: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29436289/a-comparative-analysis-of-lumbar-spine-mechanics-during-barbell-and-crate-lifting-implications-for-occupational-lifting-task-assessments
#19
Jackie D Zehr, Danielle R Carnegie, Timothy N Welsh, Tyson A C Beach
PURPOSE: To compare the effects of object handled and handgrip used on lumbar spine motion and loading during occupational lifting task simulations. METHODS: Eight male and eight female volunteers performed barbell and crate lifts with a pronated (barbell) and neutral (crate) handgrip. The mass of barbells/crates lifted was identical across the objects and fixed at 11.6 kg and 9.3 kg for men and women, respectively. The initial heights of barbells/crates were individualized to mid-shank level...
February 13, 2018: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/29432112/the-development-and-preliminary-test-of-a-powered-alternately-walking-exoskeleton-with-the-wheeled-foot-for-paraplegic-patients
#20
Qingchuan Ma, Linhong Ji, Rencheng Wang
Upright walking has both physical and social meanings for paraplegic patients. The main purpose of this paper is to reduce the automatic functioning of the powered exoskeleton and enable the user to fully control the walking procedure in real-time, aiming to further improve the engagement of the patient during rehabilitation training. For this prototype, a custom-made hub motor was placed at the bottom of the exoskeleton's foot, and a pair of crutches with the embedded wireless controller were utilized as the auxiliary device...
February 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
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