keyword
MENU ▼
Read by QxMD icon Read
search

High myopia

keyword
https://www.readbyqxmd.com/read/28442722/mutational-screening-of-slc39a5-leprel1-and-lrpap1-in-a-cohort-of-187-high-myopia-patients
#1
Chun-Yun Feng, Xiao-Qiong Huang, Xue-Wen Cheng, Rong-Han Wu, Fan Lu, Zi-Bing Jin
High myopia (HM) is a leading cause of mid-way blindness with a high heritability in East Asia. Although only a few disease genes have been reported, a small proportion of patients could be identified with genetic predispositions. In order to expand the mutation spectrum of the causative genes in Chinese adult population, we investigated three genes, SLC39A5, LEPREL1 and LRPAP1, in a cohort of 187 independent Chinese patients with high myopia. Sanger sequencing was used to find possible pathogenic mutations, which were further screened in normal controls...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28438126/prevalence-of-and-factors-associated-with-myopia-in-inner-mongolia-medical-students-in-china-a-cross-sectional-study
#2
Lan Wang, Maolin Du, He Yi, Shengyun Duan, Wenfang Guo, Peng Qin, Zhihui Hao, Juan Sun
BACKGROUND: To further explore characteristics of myopia and changes in factors associated with myopia among students at Inner Mongolia Medical University. METHODS: Two cross-sectional censuses were conducted in 2011 and 2013. Participants were medical students residing on campus in 2011 and 2013. Logistic regression analysis was performed to ascertain associations with basic information, genetic factors, environmental factors. The χ(2) test was used to test for differences in prevalence between 2011 and 2013...
April 24, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28435332/lacquer-cracks-observed-in-peripheral-fundus-of-eyes-with-high-myopia
#3
Mitsuki Suga, Kosei Shinohara, Kyoko Ohno-Matsui
We report a case with lacquer cracks observed in the peripheral fundus. A 37-year-old patient with bilateral high myopia who visited our clinic was examined by fluorescein angiography (FA) and fundus autofluorescence (FAF) to determine whether there were myopic fundus lesions. FA showed many arch-shaped, hyperfluorescent linear lesions running circumferentially in the peripheral fundus. FAF showed hypo-autofluorescence at the corresponding sites. These characteristics were very similar to the lacquer cracks present in the posterior fundus in highly myopic eyes...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28435210/incidence-of-interface-fluid-syndrome-after-laser-in-situ-keratomileusis-in-egyptian-patients
#4
Amr A Gab-Alla
PURPOSE: To determine the incidence of interface fluid syndrome (IFS) secondary to steroid-induced elevation of intraocular pressure (IOP) following laser in situ keratomileusis (LASIK) in myopic Egyptian patients. METHODS: This retrospective case series study was conducted at El-Gowhara Private Eye Center. The medical records of 1,807 patients (3,489 eyes), who underwent LASIK to correct myopia from April 2012 to December 2015 were included. The patients were operated on and reviewed by one surgeon (AAG) for IFS after LASIK associated with elevation of IOP (as compared to preoperative values)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28435208/is-high-myopia-a-risk-factor-for-visual-field-progression-or-disk-hemorrhage-in-primary-open-angle-glaucoma
#5
Koji Nitta, Kazuhisa Sugiyama, Ryotaro Wajima, Gaku Tachibana
PURPOSE: The purpose of this study was to clarify differences between highly myopic and non-myopic primary open-angle glaucoma (POAG) patients, including normal-tension glaucoma patients. PATIENTS AND METHODS: A total of 269 POAG patients were divided into two groups: patients with ≥26.5 mm of axial length (highly myopic group) and patients with <24.0 mm of axial length (non-myopic group). RESULTS: We analyzed 53 highly myopic and 93 non-myopic POAG patients...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28430758/the-refractive-error-of-professional-baseball-players
#6
Daniel M Laby, David G Kirschen
PURPOSE: High levels of visual acuity are required to hit a baseball effectively. Research has shown that any decrease in vision is likely caused by low-order optical aberrations. This study is designed to validate the SVOne autorefractor, and describe the amount and type, of low-order optical aberrations present in a large cohort of professional baseball players. METHODS: A retrospective chart review on the 608 Major League Baseball players evaluated during the 2016 Spring Training Season was performed...
May 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28430330/long-term-visual-outcomes-in-children-with-primary-congenital-glaucoma
#7
Sanaa A Yassin
PURPOSE: To determine the long-term visual outcomes and risk factors for visual loss in children with primary congenital glaucoma (PCG) who underwent angle surgery over a 21-year period. METHODS: This was a retrospective study of patients who underwent trabeculotomy, trabeculectomy, or combined trabeculotomy-trabeculectomy for PCG. Visual acuity (VA), surgeries, and underlying cause of visual impairment were recorded and compared. Main outcome measures were final best-corrected good VA (20/20 to 20/50), moderate VA (<20/50 to 20/200), or poor VA (<20/200); age at surgery, sex, laterality, type of initial glaucoma surgery, and number of surgeries were recorded...
April 20, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28426626/parapapillary-gamma-and-delta-zones-in-high-myopia
#8
Jost B Jonas, Yuxin Fang, Pascal Weber, Kyoko Ohno-Matsui
PURPOSE: To examine parapapillary zones gamma and delta in highly myopic eyes. METHODS: The retrospective observational study included patients attending the Tokyo high myopia clinics. Fundus photographs were morphometrically examined. RESULTS: The study population included 600 eyes (304 individuals) with a mean age of 62.7 ± 14.3 years (range: 13-90 years) and mean axial length of 29.6 ± 2.2 mm (range: 23.2-35.4 mm). In multivariate analysis (regression coefficient r:0...
April 19, 2017: Retina
https://www.readbyqxmd.com/read/28419360/p4ha1-mutations-cause-a-unique-congenital-disorder-of-connective-tissue-involving-tendon-bone-muscle-and-the-eye
#9
Yaqun Zou, Sandra Donkervoort, Antti M Salo, A Reghan Foley, Aileen M Barnes, Ying Hu, Elena Makareeva, Meganne E Leach, Payam Mohassel, Jahannaz Dastgir, Matthew A Deardorff, Ronald D Cohn, Wendy O DiNonno, Fransiska Malfait, Monkol Lek, Sergey Leikin, Joan C Marini, Johanna Myllyharju, Carsten G Bönnemann
Collagen prolyl 4-hydroxylases (C-P4Hs) play a central role in the formation and stabilization of the triple helical domain of collagens. P4HA1 encodes the catalytic α(I) subunit of the main C-P4H isoenzyme (C-P4H-I). We now report human bi-allelic P4HA1 mutations in a family with a congenital-onset disorder of connective tissue, manifesting as early-onset joint hypermobility, joint contractures, muscle weakness and bone dysplasia as well as high myopia, with evidence of clinical improvement of motor function over time in the surviving patient...
April 13, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28414805/measurements-of-the-parapapillary-atrophy-zones-in-en-face-optical-coherence-tomography-images
#10
Atsuya Miki, Yasushi Ikuno, Robert N Weinreb, Junko Yokoyama, Tomoko Asai, Shinichi Usui, Kohji Nishida
OBJECTIVE: To measure the parapapillary atrophy (PPA) area in en face images obtained with swept-source optical coherence tomography (SS-OCT), and to evaluate its relationship to glaucoma, myopia, and age in non-highly myopic subjects. DESIGN: Retrospective, cross-sectional study. PARTICIPANTS: Fifty eyes of 30 subjects with open-angle glaucoma (G group) and forty-three eyes of 26 healthy control subjects (C group). Eyes with high myopia (spherical equivalent refractive error ≤ -8 diopters or axial length ≥ 26...
2017: PloS One
https://www.readbyqxmd.com/read/28413744/bilateral-retinal-detachments-associated-with-inversion-table-therapy
#11
Valerie C Lerebours, Austin J Rohl, Saad Shaikh
To report a case of sequential bilateral inferior retinal detachments secondary to inversion table therapy. A 67-year-old-male developed inferior rhegmatoegnous retinal detachments (RRD) in both eyes on two different occasions with the use of inversion therapeutic tables. Various predisposing factors have been documented for RRD such as previous cataract surgery, peripheral retinal degenerations, high myopia, history of previous retinal detachments and direct ocular trauma. The authors report here a case of inferior retinal detachments associated with the use of inversion therapy...
March 15, 2017: Curēus
https://www.readbyqxmd.com/read/28412798/-intraocular-lens-power-calculation-for-high-myopic-eyes-with-cataract-comparison-of-three-formulas
#12
X J Zhu, W W He, Y Du, D J Qian, J H Dai, Y Lu
Objective: To compare the accuracy of three different formulas for intraocular lens power calculation in high myopic eyes with cataract and analyze their influencial factors. Methods: One hundred and three high myopic patients of cataract (103 eyes), with average age of 60.2±8.8 years old (39.0-77.0), including 45 male and 54 female and with axial length ≥ 26 mm were enrolled in this retrospective case-series study. All of them underwent routine ocular examination and IOLMastermeasurement preoperatively and then underwent phacoemulsification through temporal clear-corneal incision with implantation of HumanOptic posterior chamber Intraocular lens (IOL)...
April 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28410723/risk-factors-predicting-steroid-induced-ocular-hypertension-after-photorefractive-keratectomy
#13
Yumna Busool, Michael Mimouni, Igor Vainer, Shmuel Levartovsky, Tzahi Sela, Gur Munzer, Igor Kaiserman
PURPOSE: To assess the risk factors contributing to steroid-induced ocular hypertension after photorefractive keratectomy (PRK). SETTING: Care Laser Centers, Tel Aviv, Israel. DESIGN: Retrospective case series. METHODS: Patients having PRK between January 2000 and December 2015 were followed for at least 3 months. Intraocular pressure (IOP) was measured using the Goldmann applanation tonometer after 1 week and after 1, 3, and 6 months...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28410722/visual-outcomes-of-laser-vision-correction-in-eyes-with-preoperative-amblyopia
#14
Nir Sorkin, David Varssano, David Smadja, Ainat Klein, Michael Mimouni, Amir Rosenblatt
PURPOSE: To evaluate the visual outcomes of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) in amblyopic eyes. SETTING: Care Vision Refractive Clinic, Tel Aviv, Israel. DESIGN: Retrospective case series. METHODS: Amblyopic eyes of patients with a preoperative corrected distance visual acuity (CDVA) of 20/33 or worse had PRK or LASIK. Postoperative visual outcomes (uncorrected distance visual acuity, CDVA) and correlations with age, preoperative CDVA, refractive error type, astigmatism grade, procedure type, laser suite model, amblyopia grade, and amblyopia type were analyzed...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28409023/a-new-sutureless-illuminated-macular-buckle-designed-for-myopic-macular-hole-retinal-detachment
#15
Ahmed M Bedda, Ahmed M Abdel Hadi, Mohamed Lolah, Muhammad S Abd Al Shafy
Purpose. To report the anatomic and visual results of a new sutureless illuminated macular buckle designed for patients with macular hole retinal detachment related to high myopia (MMHRD). Design. Prospective nonrandomized comparative interventional trial. Methods. Twenty myopic eyes of 20 patients (mean age, 51.4 years; range, 35-65 years) presenting with MMHRD with a posterior staphyloma, in whom the new buckle was used, were evaluated. The buckle used was assembled from a 5 mm wide sponge and a 7 mm wide silicone tire; it was fixed utilizing the sterile topical adhesive Histoacryl Blue (B Braun, TS1050044FP) which polymerizes in seconds upon being exposed to water-containing substances...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28402202/correlations-between-mmps-and-timps-levels-in-aqueous-humor-from-high-myopia-and-cataract-patients
#16
Yan Jia, Dan-Ning Hu, Jing Sun, Jibo Zhou
PURPOSE: To study the relationships between matrix metalloproteinases (MMP)-2, MMP-3, and tissue inhibitors of matrix metalloproteinases (TIMP)-1, TIMP-2, and TIMP-3 aqueous humor levels in patients with high myopia or cataract. MATERIALS AND METHODS: MMPs and TIMPs protein levels in 65 aqueous humor samples collected from patients with high myopia or cataract during cataract or clear lens extraction surgery were measured with the Luminex xMAP Technology. The relationship between MMPs and TIMPs levels was analyzed with Spearman's correlation test...
April 2017: Current Eye Research
https://www.readbyqxmd.com/read/28393038/single-step-transepithelial-photorefractive-keratectomy-in-high-myopia-qualitative-and-quantitative-visual-functions
#17
Soheil Adib-Moghaddam, Saeed Soleyman-Jahi, Fatemeh Adili-Aghdam, Samuel Arba Mosquera, Niloofar Hoorshad, Salar Tofighi
AIM: To investigate quantitative and qualitative optical outcomes of single-step transepithelial photorefractive keratectomy (TransPRK) in high myopia. METHODS: In a prospective interventional case-series, 30 eyes with high myopia (-6.00 to -8.75 D) with (up to -3.00 D) or without astigmatism were enrolled from Bina Eye Hospital, Tehran, Iran. One-step TransPRK was performed with aberration-free aspherical optimized profile and SCHWIND AMARIS 500 laser. One-year follow-up results for refraction, visual acuities, vector analysis, ocular wave-front (OWF) and corneal wave-front (CWF) higher order aberrations (HOA), contrast sensitivity (CS), and post-operative haze were assessed...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28384725/predictions-of-optic-nerve-traction-forces-and-peripapillary-tissue-stresses-following-horizontal-eye-movements
#18
Xiaofei Wang, Liam K Fisher, Dan Milea, Jost B Jonas, Michaël J A Girard
Purpose: To use finite element (FE) analysis to predict the optic nerve sheath traction forces that act on the optic nerve head (ONH) following horizontal eye movements, and the resulting stress levels in the peripapillary connective tissues of the ONH (Bruch's membrane [BM] and sclera). Methods: An FE model of a healthy eye was reconstructed in primary gaze position that included details from the orbital and ONH tissues. Optic nerve sheath traction forces and peripapillary tissue stresses in both adduction and abduction (13°) were computed using FE analysis...
April 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28384719/exome-sequence-analysis-of-14-families-with-high-myopia
#19
Bethany A Kloss, Stuart W Tompson, Kristina N Whisenhunt, Krystina L Quow, Samuel J Huang, Derek M Pavelec, Thomas Rosenberg, Terri L Young
Purpose: To identify causal gene mutations in 14 families with autosomal dominant (AD) high myopia using exome sequencing. Methods: Select individuals from 14 large Caucasian families with high myopia were exome sequenced. Gene variants were filtered to identify potential pathogenic changes. Sanger sequencing was used to confirm variants in original DNA, and to test for disease cosegregation in additional family members. Candidate genes and chromosomal loci previously associated with myopic refractive error and its endophenotypes were comprehensively screened...
April 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28383074/phenotypic-and-genotypic-correlation-between-myopia-and-intelligence
#20
Katie M Williams, Pirro G Hysi, Ekaterina Yonova-Doing, Omar A Mahroo, Harold Snieder, Christopher J Hammond
Myopia, or near-sightedness, is our most common eye condition and the prevalence is increasing globally. Visual impairment will occur if uncorrected, whilst high myopia causes sight-threatening complications. Myopia is associated with higher intelligence. As both are heritable, we set out to examine whether there is a genetic correlation between myopia and intelligence in over 1,500 subjects (aged 14-18 years) from a twin birth cohort. The phenotypic correlation between refractive error and intelligence was -0...
April 6, 2017: Scientific Reports
keyword
keyword
29470
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"