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https://www.readbyqxmd.com/read/28738419/posterior-staphylomas-in-pathologic-myopia-imaged-by-widefield-optical-coherence-tomography
#1
Kosei Shinohara, Noriaki Shimada, Muka Moriyama, Takeshi Yoshida, Jost B Jonas, Nagahisa Yoshimura, Kyoko Ohno-Matsui
Purpose: To examine posterior staphylomas by widefield optical coherence tomography (WF-OCT) and three-dimensional magnetic resonance imaging (3D-MRI). Methods: Highly myopic patients (myopic refractive error >8.0 diopters or axial length >26.5 mm) who had previously undergone orbital 3D-MRI were examined by WF-OCT. Results: The study included 100 eyes of 57 patients with a mean age of 67.9 ± 10.7 years (range, 44-85 years) and mean axial length of 30...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28734810/retinal-pigment-epithelium-humps-in-high-myopia
#2
Alessandro Marchese, Adriano Carnevali, Riccardo Sacconi, Teresa Centoducati, Lea Querques, Francesco Bandello, Giuseppe Querques
PURPOSE: To report on the presence of retinal pigment epithelium (RPE) humps in high myopia, and to describe the distinctive features from pathological PEDs and choroidal neovascularizations (CNVs). DESIGN: Retrospective cross-sectional study. METHODS: Charts and imaging studies of highly myopic patients presenting between September 2015 and February 2017 at a university teaching hospital were consecutively reviewed. All patients underwent spectral domain optical coherence tomography (OCT)...
July 19, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28732616/stromal-remodeling-and-lenticule-thickness-accuracy-in-small-incision-lenticule-extraction-one-year-results
#3
Nikolaus Luft, Siegfried G Priglinger, Michael H Ring, Wolfgang J Mayer, Anna S Mursch-Edlmayr, Thomas C Kreutzer, Matthias Bolz, Martin Dirisamer
PURPOSE: To prospectively characterize the stromal thickness changes during the first year after myopic small-incision lenticule extraction using spectral-domain optical coherence tomography (SD-OCT). SETTING: Department of Ophthalmology, Kepler University Hospital, Linz, Austria. DESIGN: Prospective case series. METHODS: This study evaluated eyes that had small-incision lenticule extraction to treat myopia or myopic astigmatism...
June 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28731878/correlation-of-corneal-biomechanical-stiffness-with-refractive-error-and-ocular-biometry-in-a-pediatric-population
#4
Jyoti Matalia, Mathew Francis, Pooja Gogri, Pratibha Panmand, Himanshu Matalia, Abhijit Sinha Roy
PURPOSE: To assess the correlation between corneal biomechanical stiffness and refractive error (RE) in the pediatric population. METHODS: A total of 733 pediatric eyes were included in the study retrospectively. All eyes underwent corneal tomography (Pentacam), RE assessment, and air-puff deformation (Corvis-ST). Waveform analyses of deformation provided corneal stiffness (CS) and extraocular tissue stiffness (EOS). Eyes were subgrouped into emmetropia [manifest refraction spherical equivalent (MRSE) ∼ 0 D], hyperopia (MRSE > 0 D), myopia I (MRSE between 0 D and -3 D), myopia II (MRSE between -3 D and -6 D), and myopia III (MRSE greater than -6 D) for multivariate analyses...
July 19, 2017: Cornea
https://www.readbyqxmd.com/read/28730127/combined-phacoemulsification-and-anterior-vitrectomy-in-a-case-of-anterior-megalophthalmos-with-open-angle-glaucoma-and-high-myopia
#5
Cai-Xuan Huang, Xiao-Hui Zhao, Yi-Qiao Xing
No abstract text is available yet for this article.
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28730114/diagnostic-capability-of-peripapillary-retinal-nerve-fiber-layer-parameters-in-time-domain-versus-spectral-domain-optical-coherence-tomography-for-assessing-glaucoma-in-high-myopia
#6
Mei-Ching Teng, Yi-Chieh Poon, Kuo-Chi Hung, Hsueh-Wen Chang, Ing-Chou Lai, Jen-Chia Tsai, Pei-Wen Lin, Chien-Yun Wu, Chueh-Tan Chen, Pei-Chang Wu
AIM: To evaluate and compare the diagnostic capabilities of peripapillary retinal nerve fiber layer (p-RNFL) parameters of Spectralis optical coherence tomography (OCT) versus Stratus OCT to detect glaucoma in patients with high myopia. METHODS: This is a retrospective, cross-sectional study. Sixty highly myopic eyes of 60 patients were enrolled, with 30 eyes in the glaucoma group and 30 eyes in the control group. All eyes received peripapillary imaging of the optic disc using Stratus and Spectralis OCT...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28729370/anterior-segment-optical-coherence-tomography-angle-and-vault-analysis-after-toric-and-non-toric-implantable-collamer-lens-v4c-implantation-in-patients-with-high-myopia
#7
Guillermo Garcia-De la Rosa, Andrew Olivo-Payne, Juan Carlos Serna-Ojeda, Maria Sandra Salazar-Ramos, Alejandro Lichtinger, Arturo Gomez-Bastar, Arturo Ramirez-Miranda, Alejandro Navas, Enrique O Graue-Hernandez
OBJECTIVE: To assess anterior segment changes, including iridocorneal angle and vault, after toric and non-toric implantable collamer lens (ICL) V4c (STAAR Surgical AG) implantation under different lighting conditions. METHODS: Longitudinal, prospective, case series. Patients with high myopia (>6 dioptres) underwent toric and non-toric ICL V4c implantation. Optical coherence tomography measurements were taken under different lighting conditions preoperatively and at 1 week and 1, 6 and 12 months of follow-up...
July 20, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28726533/ophthalmic-findings-in-patients-with-arterial-tortuosity-syndrome-and-carriers-a-case-series
#8
Joshua S Hardin, Yuri A Zarate, Bert Callewaert, Paul H Phillips, David B Warner
INTRODUCTION: Arterial tortuosity syndrome (ATS) is a rare autosomal recessive disease hallmarked by tortuosity, stenosis, and aneurysm development of large- and medium-sized arteries. Mutations in SLC2A10, a gene that encodes the facilitative glucose transporter GLUT10, cause ATS. Several case reports have noted associated ophthalmic findings such as keratoconus, keratoglobus, and myopia without detailed descriptions or standardized examinations. We report the ophthalmic findings in a cohort of compound heterozygous ATS patients and heterozygous carriers of SLC2A10 mutations...
July 20, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28722276/identification-and-functional-analysis-of-an-adamtsl1-variant-associated-with-a-complex-phenotype-including-congenital-glaucoma-craniofacial-and-other-systemic-features-in-a-three-generation-human-pedigree
#9
Kathryn Hendee, Lauren Weiping Wang, Linda M Reis, Gregory M Rice, Suneel S Apte, Elena V Semina
Developmental glaucoma can occur as an isolated or syndromic condition and is genetically heterogeneous. We describe a three-generation family affected with developmental glaucoma, myopia, and/or retinal defects associated with variable craniofacial/dental, auditory, brain, renal, and limb anomalies. Whole exome sequencing identified a heterozygous c.124T> C, p.(Trp42Arg) allele in ADAMTSL1; co-segregation analysis confirmed the presence of this allele in four affected family members. The mutation affects a highly conserved residue and is strongly predicted to have a deleterious effect on protein function...
July 19, 2017: Human Mutation
https://www.readbyqxmd.com/read/28721935/prevalence-of-eye-disease-and-visual-impairment-in-%C3%A3-le-de-la-gonave-ha%C3%A3-ti
#10
B Tousignant, J Brûlé
Epidemiological data describing the prevalence of blindness and visual impairment in Haiti are sparse. The Haitian National Committee for the Prevention of Blindness (CNPC) estimates the prevalence of blindness at 1 %. Other regional data estimate moderate and severe visual impairment at 5% and 22%, respectively. IRIS Mundial (IM) is a non-governmental organization collaborating with the CNPC to develop eye care infrastructure in Haiti. To estimate the prevalence and causes of blindness and visual impairment on the Haitian island of Gonâve, to assist in planning of relevant eye care infrastructure...
July 19, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28718190/-prevalence-and-risk-factors-of-myopia-in-children-and-adolescents-in-germany-results-of-the-kiggs-survey
#11
Alexander K Schuster, Heike M Elflein, Roman Pokora, Michael S Urschitz
Purpose To determine the population prevalence and risk factors of myopia in children and adolescents in Germany. Methods The prevalence of myopia in Germany was computed using data from the 2003-2006 German Health Interview and Examination Survey for Children and Adolescents (N=17 640, 49% girls). Status of myopia was derived from parental questionnaire responses for myopia and the use of spectacles. Potential risk factors were identified using directed acyclic graphs and evaluated using multivariable logistic regression analysis...
July 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28715588/caucasian-families-exhibit-significant-linkage-of-myopia-to-chromosome-11p
#12
Anthony M Musolf, Claire L Simpson, Bilal A Moiz, Kyle A Long, Laura Portas, Federico Murgia, Elise B Ciner, Dwight Stambolian, Joan E Bailey-Wilson
Purpose: Myopia is a common visual disorder caused by eye overgrowth, resulting in blurry vision. It affects one in four Americans, and its prevalence is increasing. The genetic mechanisms that underpin myopia are not completely understood. Here, we use genotype data and linkage analyses to identify high-risk genetic loci that are significantly linked to myopia. Methods: Individuals from 56 Caucasian families with a history of myopia were genotyped on an exome-based array, and the single nucleotide polymorphism (SNP) data were merged with microsatellite genotype data...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28710187/utility-of-microscope-integrated-optical-coherence-tomography-mioct-in-the-treatment-of-myopic-macular-hole-retinal-detachment
#13
Atul Kumar, Prateek Kakkar, Raghav Dinesh Ravani, Ashish Markan
Macular hole-associated retinal detachment in high myopia is described as a final stage in progression of myopic traction maculopathy (MTM).(1â€"3) Shimada et al(4) described the progressive stages of MTM from macular retinoschisis to serous retinal detachment in high myopia. Stage 4 MTM is characterised as disappearance of retinoschisis with progression to retinal detachment due to macular hole formation. It is hypothesised that vitreoschisis and abnormal vitreo-retinal interface create the premacular tangential traction...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28696042/reduced-vision-in-highly-myopic-eyes-without-ocular-pathology-the-zoc-bhvi-high-myopia-study
#14
Monica Jong, Padmaja Sankaridurg, Wayne Li, Serge Resnikoff, Kovin Naidoo, Mingguang He
BACKGROUND: The aim was to investigate the relationship of the magnitude of myopia with visual acuity in highly myopic eyes without ocular pathology. METHODS: Twelve hundred and ninety-two highly myopic eyes (up to -6.00 DS both eyes, no astigmatic cut-off) with no ocular pathology from the ZOC-BHVI high myopia study in China, had cycloplegic refraction, followed by subjective refraction and visual acuities and axial length measurement. Two logistic regression models were undertaken to test the association of age, gender, refractive error, axial length and parental myopia with reduced vision...
July 11, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/28692503/acquired-adult-onset-cyclic-esotropia-in-patients-with-myopic-strabismus-fixus-and-intraocular-lens-implantation
#15
Jianhua Yan, Yun Wen
PURPOSE/BACKGROUND: Cyclic esotropia is a rare condition that mostly occurs in children, characterized by patterns of straight and strabismic days with a regular cycle of 24 to 96 hours. In this report, 2 patients of cyclic esotropia in adults who showed a regular 48-hour cycle of mild deviation on 1 day followed by a more severe deviation on the second day are presented. METHODS: Clinical reports, clinical features, imaging findings, and surgical outcomes are presented...
July 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28687852/optical-coherence-tomographic-imaging-of-posterior-episclera-and-tenon-s-capsule
#16
Kyoko Ohno-Matsui, Yuxin Fang, Kei Morohoshi, Jost B Jonas
Purpose: To investigate structural features of the posterior episclera and Tenon's capsule in patients with high myopia. Methods: This hospital-based observational study included highly myopic eyes (myopic refractive error > -8 diopters or axial length ≥26.5 mm) in which the posterior sclera in its full thickness could be visualized on swept-source optical coherence tomography (OCT) images in all 12 radial scans centered on the fovea. We assessed the posterior episclera and Tenon's capsule...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28683793/comparison-of-visual-results-and-higher-order-aberrations-after-small-incision-lenticule-extraction-smile-high-myopia-vs-mild-to-moderate-myopia
#17
Hong-Ying Jin, Ting Wan, Fang Wu, Ke Yao
BACKGROUND: To compare the refractive results and higher-order aberrations (HOAs) after small incision lenticule extraction (SMILE) in high myopia and mild to moderate myopia patients. METHODS: This prospective study included 165 eyes (86 patients) undergoing SMILE. According to the preoperative spherical equivalent (SE), treated eyes were divided into two groups: the high myopia group (more than -6.0 D, group-H) and the mild to moderate group (less than -6.0 D, group-M)...
July 6, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28682947/interocular-asymmetry-in-choroidal-thickness-and-retinal-sensitivity-in-high-myopia
#18
Zeyad Alzaben, Genís Cardona, Miguel A Zapata, Ahmad Zaben
PURPOSE: To investigate the normal range of interocular asymmetry in choroidal thickness and retinal sensitivity in high myopia without ocular fundus manifestations and to determine the relationship between interocular asymmetry and refractive error. METHODS: Forty-three patients (35.07 ± 13.31 years) with high myopia and 45 healthy participants (39.9 ± 14.1 years) were administered an ocular coherence tomography and a microperimetry examination to determine choroidal thickness and retinal sensitivity at the foveal region and at 1, 2, and 3 mm, nasally, temporally, superiorly, and inferiorly...
July 6, 2017: Retina
https://www.readbyqxmd.com/read/28675893/using-high-resolution-3d-magnetic-resonance-imaging-to-quantitatively-analyze-the-shape-of-eyeballs-with-high-myopia-and-provide-assistance-for-posterior-scleral-reinforcement
#19
Baohong Wen, Ge Yang, Jingliang Cheng, Xuemin Jin, Huixia Zhang, Feifei Wang, Chenyu Yan, Dandan Zheng, Tianyong Xu
PURPOSE: To quantitatively analyze the shape of eyes with high myopia and provide assistance for posterior scleral reinforcement (PSR) using high-resolution three-dimensional (3D) magnetic resonance imaging (MRI). METHOD: In all, 260 eyes of 134 patients with high myopia were assessed in this study; 120 emmetropic volunteers were enrolled as a control group. The subjects were examined using 3D T2-weighted CUBE sequences. RESULTS: The eyeballs' axial, horizontal, and vertical lengths were longer and their volume was larger in the subjects with high myopia than in those with emmetropia...
July 5, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28669042/paravascular-inner-retinal-abnormalities-in-healthy-eyes
#20
Rie Osaka, Saki Manabe, Yukiko Miyoshi, Yuki Nakano, Ayana Yamashita, Chieko Shiragami, Kazuyuki Hirooka, Yuki Muraoka, Akitaka Tsujikawa
PURPOSE: To investigate the prevalence and characteristics of paravascular inner retinal abnormalities in healthy eyes. MATERIALS AND METHODS: In this prospective observational case series, we included 178 healthy eyes (178 patients) with no ocular diseases. Eyes with co-existing ocular diseases, e.g., epiretinal membrane, glaucoma, or high myopia, were excluded from the current study. The posterior pole and paravascular areas of the temporal arcade vessels were comprehensively examined by dense radial scanning of optical coherence tomography (OCT) with the extended field imaging technique...
July 2, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
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