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High myopia

Zhong Lin, Tie Ying Gao, Balamurali Vasudevan, Kenneth J Ciuffreda, Yuan Bo Liang, Vishal Jhanji, Su Jie Fan, Wei Han, Ning Li Wang
BACKGROUND: The near work and outdoor activity are the most important environmental risk factors for myopia. However, data from Chinese rural children are relatively rare and remain controversial. Therefore, the purpose of this study was to evaluate the relationship of both near work and outdoor activities with refractive error in rural children in China. METHODS: In this cross-sectional study, 572 (65.1%) of 878 children (6-18 years of age) were included from the Handan Offspring Myopia Study (HOMS)...
November 17, 2017: BMC Ophthalmology
Tao Fu, Jing Wang, Moran Levin, Ping Xi, Dongguo Li, Junfa Li
Acute acquired comitant esotropia (AACE) is an unusual presentation of esotropia that occurs after infancy. This study was aimed to study the clinical features and the differences between children and adult patients with AACE in the Chinese populations.This was a retrospective analysis of patients diagnosed with AACE over 4 years; 69 patients (25 females and 44 males) were identified. The patients were divided into 3 groups: < 10 year-old (n = 6, 8.7%), 10-18 year-old (n = 23, 33.3%), and ≥18 year-old (n = 40, 58...
November 2017: Medicine (Baltimore)
André Lins de Medeiros, André Gustavo de Araújo Rolim, Antonio Francisco Pimenta Motta, Bruna Vieira Ventura, César Vilar, Mário Augusto Pereira Dias Chaves, Pedro Carlos Carricondo, Wilson Takashi Hida
Purpose: The purpose of this study was to compare the visual outcomes and subjective visual quality between bilateral implantation of a diffractive trifocal intraocular lens, Alcon Acrysof IQ(®) PanOptix(®) TNFT00 (group A), and blended implantation of an extended depth of focus lens, J&J Tecnis Symfony(®) ZXR00 with a diffractive bifocal intraocular lens, J&J Vision Tecnis(®) ZMB00 (group B). Methods: This prospective, nonrandomized, consecutive, comparative study included the assessment of 40 eyes in 20 patients implanted with multifocal intraocular lens...
2017: Clinical Ophthalmology
Miao He, Wei Wang, Hui Ding, Xingwu Zhong
SIGNIFICANCE: The cornea is a viscoelastic tissue with viscous and elastic properties. The information of corneal biomechanical changes in high myopia has implications for understanding the pathogenesis of high myopia and primary open angle glaucoma. However, the knowledge of corneal biomechanics in high myopia is limited. PURPOSE: To compare the corneal biomechanical properties in high-myopia subjects and emmetropia subjects. METHODS: Dynamic Scheimpflug imaging technology was used to measure intraocular pressure, central corneal thickness, and corneal biomechanical parameters, including time at the first applanation, velocity at the first applanation, length at the first applanation, deformation amplitude at the first applanation, time at the second applanation, A2V (velocity at the second applanation), length at the second applanation (A2L), deformation amplitude at the second applanation, time at the highest concavity, radius curvature at the highest concavity (HCR), maximal deformation amplitude (MDA), and peak distance...
November 10, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Irena Tsui, Alison Chu
Retinopathy of prematurity (ROP) is a condition seen in premature infants that is characterized by abnormal retinal blood vessel growth incited by relative hyperoxia and followed by hypoxia. It can have severe consequences ranging from high myopia to blindness. This article reviews recent "hot" topics related to ROP, specifically the changing incidence of ROP worldwide, the advent of predictive algorithms for screening for ROP, the emerging data behind efficacy of anti-vascular endothelial growth factor treatments for ROP, and advanced retinal imaging in children who were born premature...
November 1, 2017: Pediatric Annals
Yin Guo, Jia Li Duan, Li Juan Liu, Ying Sun, Ping Tang, Yan Yun Lv, Liang Xu, Jost B Jonas
PURPOSE: To assess prevalence and associated factors of myopia and high myopia in schoolchildren in Greater Beijing. METHODS: The school-based, cross-sectional Greater Beijing School Children Myopia study was carried out in the year 2016 in 54 schools randomly selected from 15 districts in Beijing. Non-cycloplegic auto-refractometry of the right eyes was performed. RESULTS: The study included 35,745 (99.4%) out of 35,968 eligible pupils with a mean age of 12...
2017: PloS One
Samuel Otabor Wajuihian, Rekha Hansraj
SIGNIFICANCE: This study focused on a cohort that has not been studied and who currently have limited access to eye care services. The findings, while improving the understanding of the distribution of refractive errors, also enabled identification of children requiring intervention and provided a guide for future resource allocation. PURPOSE: The aim of conducting the study was to determine the prevalence and distribution of refractive error and its association with gender, age, and school grade level...
November 9, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Praveen Jeyaseelan, Tulika Kar, P Vijayalakshmi
Periventricular leukomalacia (PVL) is coagulation necrosis of white matter seen in preterm, low birth weight (LBW) infants and associated with a range of ocular manifestations. We report a case of 2½ months old (47 weeks gestational age) female infant with PVL associated with bilateral high myopia (-16 DS). On examination, child had difficulty in tracking objects and inferior field defect with preference for superior gaze. She was prescribed spectacles and visual stimulation exercises to preserve existing vision and prevent amblyopia...
September 2017: Oman Journal of Ophthalmology
Steven C Schallhorn, David Teenan, Jan A Venter, Julie M Schallhorn, Keith A Hettinger, Stephen J Hannan, Martina Pelouskova
PURPOSE: To compare clinical and quality of life outcomes between patients who underwent monovision LASIK and refractive lens exchange. METHODS: The study comprised 590 patients with refractive lens exchange and 608 patients with monovision LASIK available for 3-month postoperative clinical visits. All patients with refractive lens exchange had a Tecnis Symfony lens (Johnson & Johnson Vision Care, Inc., Santa Ana, CA) in at least one eye. Patients were divided into four refractive categories: moderate to high myopia, low myopia, plano presbyopia, and hyperopia...
November 1, 2017: Journal of Refractive Surgery
Padmaja Sankaridurg, Xiangui He, Thomas Naduvilath, Minzhi Lv, Arthur Ho, Earl Smith, Paul Erickson, Jianfeng Zhu, Haidong Zou, Xun Xu
PURPOSE: To systematically analyse the differences between cycloplegic and noncycloplegic refractive errors (RE) in children and to determine if the predictive value of noncycloplegic RE in categorizing RE can be improved. METHODS: Random cluster sampling was used to select 6825 children aged 4-15 years. Autorefraction was performed under both noncycloplegic and cycloplegic (induced with 1% cyclopentolate drops) conditions. Paired differences between noncycloplegic and cycloplegic spherical equivalent (SE) RE were determined...
November 2017: Acta Ophthalmologica
W Wesemann
OBJECTIVE: To determine whether the prevalence and magnitude of myopia among children and young adults wearing spectacles has increased in Germany from 2000 to 2015. MATERIAL AND METHODS: A total of 1,223,410 refraction values from 278,432 male and 333,273 female subjects between 5 and 30 years of age were analyzed. All subjects had received a new pair of spectacles between 1 January 2000 and 31 December 2015. The parameter studied was the spherical equivalent averaged over both eyes of each subject (N = 611,705)...
November 6, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Hidemasa Torii, Kazuhiko Ohnuma, Toshihide Kurihara, Kazuo Tsubota, Kazuno Negishi
Myopia is increasing worldwide. Although the exact etiology of myopia is unknown, outdoor activity is one of the most important environmental factors for myopia control. We previously reported that violet light (VL, 360-400 nm wavelength), which is abundant in the outdoor environment, suppressed myopia progression for individuals under 20 years of age. However, whether VL is also effective for adult high myopia, which can be sight-threatening, has remained unknown. To investigate the influence of VL for adult myopia, we retrospectively compared the myopic progression and the axial length elongation over five years in adult high myopic patients over 25 years of age after two types (non-VL transmitting and VL transmitting) of phakic intraocular lens (pIOL) implantation...
November 6, 2017: Scientific Reports
Binbin Su, Bin Zhang, Junping Huang, Wen Xie, Zhenyu Wu, Meng Lin, Zheyi Chen, Haoran Wu, Jun Jiang, Fan Lu
BACKGROUND: The aim was to evaluate the effect of transient glare on shape discrimination threshold (SDT) in myopic adults. METHODS: A total of 162 myopic subjects were enrolled. Of these, 121 had low to mid myopia (-1.00 D to -6.00 D) and 41 had high myopia (-6.13 D to -10.25 D). All subjects had corrected visual acuity of 6/6 or better, and only data for the right eye were included in the study. SDTs were measured with circular D4 (fourth derivative of Gaussian) radial frequency patterns with a radial frequency of four, peak spatial frequency of three cpds, and mean radius of 1...
October 27, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Hiroyuki Takahashi, Makoto Inoue, Takashi Koto, Yuji Itoh, Kazunari Hirota, Akito Hirakata
PURPOSE: To compare the efficacy of vitrectomy with inverted internal limiting membrane (ILM) flap to complete removal of the ILM for the treatment of macular hole (MH) retinal detachment in highly myopic eyes. METHODS: Pars plana vitrectomy with inverted ILM flap technique (16 eyes; inverted group) or with the complete removal of the ILM (16 eyes; removed group) was performed in patients with high myopia with MH retinal detachment. The rate of retinal reattachment and MH closure, the best-corrected visual acuities, and the integrity of the foveal microstructures in the optical coherence tomographic images were compared...
October 23, 2017: Retina
Gui-Fang Wang, Qing-Shan Ji, Bing Qi, Guo-Cheng Yu, Lian Liu, Jing-Xiang Zhong
AIM: To investigate the correlation between lumican (LUM) gene and high myopia in a Southern Chinese population. METHODS: The study comprised of 95 high myopia patients with a spherical equivalent ≤-6.5 diopters (D). The control group recruited 95 individuals with a spherical equivalent ranging from -0.5 D to +0.5 D. Direct sequencing was used to detect the single nucleotide polymorphisms (SNPs) of LUM gene in coding region. Genotype distributions were tested for Hardy-Weinberg disequilibrium...
2017: International Journal of Ophthalmology
Muna A Al Dhaibani, Diane Allingham-Hawkins, Ayman W El-Hattab
BACKGROUND: Studying human genome using chromosomal microarrays has significantly improved the accuracy and yield of diagnosing genomic disorders. Chromosome 7q36 deletions and duplications are rare genomic disorders that have been reported in a limited number of children with developmental delay, growth retardation, and congenital malformation. Altered dosage of SHH and HLXB9, both located in 7q36.3, is believed to play roles in the phenotypes associated with these rearrangements. In this report we describe a child with 7q36...
October 23, 2017: BMC Medical Genetics
Li Hepei, Xie Mingkun, Wang Li, Wu Jin
PURPOSE: The aim is to evaluate the association between high myopia and genetic variant in the BicC family RNA binding protein 1 (BICC1) as well as its association with Ras protein specific guanine nucleotide releasing factor 1 (RASGRF1) genes in a Chinese Han population with a case-control study. METHODS: Five TagSNPs in BICC1 and RASGRF1 genes were selected and genotyped in 821 unrelated subjects, which composed of 419 controls (spherical equivalent within ±1...
October 2017: Indian Journal of Ophthalmology
Cailian Xu, Chenwei Pan, Chunhua Zhao, Mingchao Bi, Qinghua Ma, Jianhui Cheng, E Song
BACKGROUND: To determine the prevalence and associated factors for myopia and high myopia among older population in a rural community in Eastern China. METHODS: A community-based, cross-sectional survey was conducted in the Weitang town located in Suzhou, an urban metropolis in East China. A total of 5613 Chinese residents aged 60 years and older were invited to complete a questionnaire and participated in a detailed eye examination,including measurements of visual acuity and refractive error using autorefraction and subjective refraction...
October 13, 2017: BMC Ophthalmology
K-C Xue, D-D Hu, L Zhao, N Li, H-Y Shen
OBJECTIVE: The objective of this study was to examine the correlation between the presence of primary iris-ciliary cysts and the intraocular pressure. PATIENTS AND METHODS: Sixty patients with short-sightedness undergoing routine examination for laser vision correction in our hospital in 2003 were enrolled. Patients with known high intraocular pressure and risk of glaucoma were excluded from the study. A total of 119 eyes were examined by the Ultrasound Biomicroscope (UBM), and the presence of the primary iris-ciliary cysts was confirmed...
September 2017: European Review for Medical and Pharmacological Sciences
Qinghui Kong, Jiang Guo, Jing Zhou, Yanling Zhang, Xiaoyan Dou
BACKGROUND: We aimed to identify factors influencing the therapeutic outcome of orthokeratology on controlling juvenile myopia progression, and the risk factors for complications. METHODS: Myopic patients (n=724) in Shenzhen Second Hospital from Jan 2011 to Jan 2016 fitted with orthokeratology lenses and followed-up for 6-65 months were reviewed retrospectively. Univariate and multivariate logistic regression analyses were used to screen for the factors that can improve treatment outcome and prevent the development of complications...
September 2017: Iranian Journal of Public Health
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