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McKenzie Method

Christina Wegeberg, Christian Grundahl Frankær, Christine J McKenzie
The iodine L3-edge X-ray Absorption Near Edge Structure (XANES) of organic and inorganic iodine compounds with formal iodine oxidation states ranging from -1 to +7 shows edge energies spanning from 4560.8 eV to 4572.5 eV. These were used to calibrate the oxidation state of iodine in a unique iron complex of iodosylbenzene (PhIO), [Fe(tpena)OIPh](2+) (tpena(-) = N,N,N'-tris(2-pyridylmethyl)ethylenediamine-N'-acetate), which was found to be +1.6. Thus the iodine oxidation state is reduced by 1.4 compared with that in precursor uncoordinated PhIO...
October 20, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
Thomas L McKenzie
Physical activity is place-based, and being able to assess the number of people and their characteristics in specific locations is important both for public health surveillance and for practitioners in their design of physical activity spaces and programs. Although physical activity measurement has improved recently, many investigators avoid or are at a loss regarding the assessment of physical activity in explicit locations, especially in open environments where many people come and go in a seemingly indiscriminate fashion...
October 17, 2016: Research Quarterly for Exercise and Sport
Sean S E Collins, Xingzhan Wei, Thomas McKenzie, Alison M Funston, Paul Mulvaney
A reliable and reproducible method to rapidly charge single gold nanocrystals in a solid-state device is reported. Gold nanorods (Au NRs) were integrated into an ion gel capacitor, enabling them to be charged in a transparent and highly capacitive device, ideal for optical transmission. Changes in the electron concentration of a single Au NR were observed with dark field imaging spectroscopy via localised surface plasmon resonance (LSPR) shifts in the scattering spectrum. A time-resolved, laser-illuminated, dark field system was developed to enable direct measurement of single particle charging rates with time resolution below one millisecond...
October 4, 2016: Nano Letters
Dylan J Irvine, Martin A Briggs, Laura K Lautz, Ryan P Gordon, Jeffrey M McKenzie, Ian Cartwright
Heat is a powerful tracer to quantify fluid exchange between surface water and groundwater. Temperature time series can be used to estimate pore water fluid flux, and techniques can be employed to extend these estimates to produce detailed plan-view flux maps. Key advantages of heat tracing include cost-effective sensors and ease of data collection and interpretation, without the need for expensive and time-consuming laboratory analyses or induced tracers. While the collection of temperature data in saturated sediments is relatively straightforward, several factors influence the reliability of flux estimates that are based on time series analysis (diurnal signals) of recorded temperatures...
October 3, 2016: Ground Water
Manuela Ferrari, Farah Ahmad, Yogendra Shakya, Cliff Ledwos, Kwame McKenzie
BACKGROUND: The worldwide rise in common mental disorders (CMDs) is posing challenges in the provision of and access to care, particularly for immigrant, refugee and racialized groups from low-income backgrounds. eHealth tools, such as the Interactive Computer-Assisted Client Assessment Survey (iCCAS) may reduce some barriers to access. iCCAS is a tablet-based, touch-screen self-assessment completed by clients while waiting to see their family physician (FP) or nurse practitioner (NP)...
2016: BMC Health Services Research
Rosemary McKenzie
BACKGROUND: The 'after hours GP helpline' (AGPH) was added to the nurse triage and advice services in Australia in July 2011 with the intention of improving access to general practitioner (GP) advice in the after-hours period. OBJECTIVE: The objectives of the article are to examine consumer awareness, satisfaction, motivation for use and perceived benefits of using the AGPH. METHODS: A mixed-methods approach used secondary data on population awareness and caller satisfaction, and an in-depth qualitative study of consumers...
July 2016: Australian Family Physician
Seth Peterson, Cheri Hodges
BACKGROUND: Lumbar lateral shift (LLS) is a common clinical observation but has rarely been described in a patient with a history of lumbar surgery. The purpose of the current case report was to describe the use of the McKenzie Method of Mechanical Diagnosis and Therapy (MDT) in the multi-modal treatment of a patient with an LLS and a history of multiple surgical procedures in the lumbar spine, including interspinous process device (IPD) implantation. CASE DESCRIPTION: A 72-year-old female with chronic low back pain (LBP) and a surgical history in the lumbar spine was referred to physical therapy for radiating leg pain and presented with a right LLS...
September 2016: Journal of Manual & Manipulative Therapy
Erin Mundy, Tom Gleeson, Mark Roberts, Michel Baraer, Jeffrey M McKenzie
Quantifying groundwater flow at seepage faces is crucial because seepage faces influence the hydroecology and water budgets of watersheds, lakes, rivers and oceans, and because measuring groundwater fluxes directly in aquifers is extremely difficult. Seepage faces provide a direct and measurable groundwater flux but there is no existing method to quantitatively image groundwater processes at this boundary. Our objective is to determine the possibilities and limitations of thermal imagery in quantifying groundwater discharge from discrete seeps...
August 30, 2016: Ground Water
Ashley Bowser, Brian T Swanson
BACKGROUND/PURPOSE: The McKenzie Method of mechanical diagnosis and therapy (MDT) is supported in the literature as a valid and reliable approach to the management of spine injuries. It can also be applied to the peripheral joints, but has not been explored through research to the same extent. This method sub-classifies an injury based on tissue response to mechanical loading and repeated motion testing, with directional preferences identified in the exam used to guide treatment. The purpose of this case report is to demonstrate the assessment, intervention, and clinical outcomes of a subject classified as having a shoulder derangement syndrome using MDT methodology...
August 2016: International Journal of Sports Physical Therapy
Britney N Lizama-Manibusan, Sharon Klein, Jennifer R McKenzie, David E Cliffel, BethAnn McLaughlin
The ability to assess oxygenation within living cells is much sought after to more deeply understand normal and pathological cell biology. Hypoxia Red manufactured by Enzo Life Sciences is advertised as a novel hypoxia detector dependent on nitroreducatase activity. We sought to use Hypoxia Red in primary neuronal cultures to test cell-to-cell metabolic variability in response to hypoxic stress. Neurons treated with 90 min of hypoxia were labeled with Hypoxia Red. We observed that, even under normoxic conditions neurons expressed fluorescence robustly...
September 21, 2016: ACS Chemical Neuroscience
Mark W Werneke, Susan Edmond, Daniel Deutscher, Jason Ward, David Grigsby, Michelle Young, Troy McGill, Brian McClenahan, Jon Weinberg, Amy L Davidow
Study Design Retrospective cohort. Background Patient-classification subgroupings may be important prognostic factors explaining outcomes. Objectives To determine effects of adding classification variables (McKenzie syndrome and pain patterns, including centralization and directional preference; Symptom Checklist Back Pain Prediction Model [SCL BPPM]; and the Fear-Avoidance Beliefs Questionnaire subscales of work and physical activity) to a baseline risk-adjusted model predicting functional status (FS) outcomes...
September 2016: Journal of Orthopaedic and Sports Physical Therapy
Malcolm M Wells, Zhe Li, Bryan Addeman, Charles A McKenzie, Amol Mujoomdar, Melanie Beaton, Jeffery Bird
Background/Aims. Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease that can progress to cirrhosis and hepatocellular carcinoma. This retrospective chart review investigated the incidence of hepatic steatosis in London, Ontario, Canada. Methods. A retrospective chart review was performed on emergency room (ER) patients undergoing nonscheduled computed tomography (CT) imaging over a six-month period in London, Ontario. CT images and reports were examined to determine presence of steatosis. Analyses of the electronic chart for a period of six months following the CT and communication with the patients' family doctors were used to determine if there was follow-up...
2016: Canadian Journal of Gastroenterology & Hepatology
Jing M Ren, Thomas G McKenzie, Qiang Fu, Edgar H H Wong, Jiangtao Xu, Zesheng An, Sivaprakash Shanmugam, Thomas P Davis, Cyrille Boyer, Greg G Qiao
Recent advances in controlled/living polymerization techniques and highly efficient coupling chemistries have enabled the facile synthesis of complex polymer architectures with controlled dimensions and functionality. As an example, star polymers consist of many linear polymers fused at a central point with a large number of chain end functionalities. Owing to this exclusive structure, star polymers exhibit some remarkable characteristics and properties unattainable by simple linear polymers. Hence, they constitute a unique class of technologically important nanomaterials that have been utilized or are currently under audition for many applications in life sciences and nanotechnologies...
June 22, 2016: Chemical Reviews
Matthew McKenzie, David Betts, Amy Suh, Kathryn Bui, Rui Tang, Kexian Liang, Samuel Achilefu, Glen S Kwon, Hyunah Cho
PURPOSE: The purpose of this study is to investigate a sol-gel transition property and content release profiles for thermosensitive poly-(D,L-lactide-co-glycolide)-block-poly-(ethylene glycol)-block-poly-(D,L-lactide-co-glycolide) (PLGA-b-PEG-b-PLGA) hydrogels carrying paclitaxel, rapamycin, and LS301, and to present a proof-of-concept that PLGA-b-PEG-b-PLGA hydrogels carrying paclitaxel, rapamycin, and LS301, called TheranoGel, exhibit excellent theranostic activity in peritoneal ES-2-luc ovarian cancer xenograft mice...
September 2016: Pharmaceutical Research
Nathan Fuller, Loredana Spadola, Scott Cowen, Joe Patel, Heike Schönherr, Qing Cao, Andrew McKenzie, Fredrik Edfeldt, Al Rabow, Robert Goodnow
Modest success rates in fragment-based lead generation (FBLG) projects at AstraZeneca (AZ) prompted operational changes to improve performance. In this review, we summarize these changes, emphasizing the construction and composition of the AZ fragment library, screening practices and working model. We describe the profiles of the screening method for specific fragment subsets and statistically assess our ability to follow up on fragment hits through near-neighbor selection. Performance analysis of our second-generation fragment library (FL2) in screening campaigns illustrates the complementary nature of flat and 3D fragments in exploring protein-binding pockets and highlights our ability to deliver fragment hits using multiple screening techniques for various target classes...
August 2016: Drug Discovery Today
Mark H Halliday, Evangelos Pappas, Mark J Hancock, Helen A Clare, Rafael Z Pinto, Gavin Robertson, Paulo H Ferreira
Study Design Randomized clinical trial. Background Motor control exercises are believed to improve coordination of the trunk muscles. It is unclear whether increases in trunk muscle thickness can be facilitated by approaches such as the McKenzie method. Furthermore, it is unclear which approach may have superior clinical outcomes. Objectives The primary aim was to compare the effects of the McKenzie method and motor control exercises on trunk muscle recruitment in people with chronic low back pain classified with a directional preference...
July 2016: Journal of Orthopaedic and Sports Physical Therapy
Adam Meekings, Sarah Utz, Martina Ulrich, Amanda Bienenfeld, Naveen Nandanan, Juliya Fisher, Gordon McKenzie, Daniel M Siegel, Eleanor Feldman, Orit Markowitz
BACKGROUND: Optical coherence tomography (OCT) is a technique that enables real-time in-vivo examination of tissue. This technology provides the clinician with the potential to use a non-invasive tool in the identification and diagnosis of many skin lesions. However, the diagnostic features of basal cell carcinoma have not yet been described with comparison to their histopathology.<br /> OBJECTIVES: To identify and describe key features of basal cell carcinoma (BCC) and its subtypes as they present in multi-beam Swept Source - OCT (MSS-OCT), and to correlate those against conventional histopathology...
May 1, 2016: Journal of Drugs in Dermatology: JDD
Sung-Yong Choi, Jung-Hyun Choi
[Purpose] The purpose of this study was to examine the effects of cervical traction treatment, cranial rhythmic impulse treatment, a manual therapy, and McKenzie exercise, a dynamic strengthening exercise, on patients who have the neck muscle stiffness of the infrequent episodic tension-type (IETTH) headache and frequent episodic tension-type headache(FETTH), as well as to provide the basic materials for clinical interventions. [Subjects] Twenty-seven subjects (males: 15, females: 12) who were diagnosed with IETTH and FETTH after treatment by a neurologist were divided into three groups: (a cervical traction group (CTG, n=9), a cranial rhythmic contractiongroup (CRIG, n=9), and a McKenzie exercise group (MEG, n=9)...
March 2016: Journal of Physical Therapy Science
Matthew J Page, Andrew Forbes, Marisa Chau, Sally E Green, Joanne E McKenzie
OBJECTIVE: To explore whether systematic reviewers selectively include trial effect estimates in meta-analyses when multiple are available, and what impact this may have on meta-analytic effects. DESIGN: Cross-sectional study. DATA SOURCES: We randomly selected systematic reviews of interventions from 2 clinical specialties published between January 2010 and 2012. The first presented meta-analysis of a continuous outcome in each review was selected (index meta-analysis), and all trial effect estimates that were eligible for inclusion in the meta-analysis (eg, from multiple scales or time points) were extracted from trial reports...
2016: BMJ Open
James F McKenzie, Dixie Dennis, M Elaine Auld, Linda Lysoby, Eva Doyle, Patricia M Muenzen, Carla M Caro, Cynthia S Kusorgbor-Narh
The Health Education Specialist Practice Analysis 2015 (HESPA 2015) was conducted to update and validate the Areas of Responsibilities, Competencies, and Sub-competencies for Entry- and Advanced-Level Health Education Specialists. Two data collection instruments were developed-one was focused on Sub-competencies and the other on knowledge items related to the practice of health education. Instruments were administered to health education specialists (N = 3,152) using online survey methods. A total of 2,508 survey participants used 4-point ordinal scales to rank Sub-competencies by frequency of use and importance...
June 2016: Health Education & Behavior: the Official Publication of the Society for Public Health Education
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