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McKenzie Method

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https://www.readbyqxmd.com/read/28614809/monitoring-body-water-balance-in-pregnant-and-nursing-women-the-validity-of-urine-color
#1
Amy L McKenzie, Lawrence E Armstrong
BACKGROUND: Urine osmolality (UOSM) reflects the renal regulation of excess fluid or deficit fluid, and therefore, serves as a marker of hydration status. Little is known about monitoring hydration in pregnant and lactating women despite significant physiological challenges to body water balance during that time. Therefore, we designed a study to assess if urine color (UCOL), an inexpensive and practical method, was a valid means of assessing urine concentration. Twenty-four hour UCOL was significantly correlated with 24 h UOSM in all women: pregnant, lactating, and control (r = 0...
2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28599897/to-the-point-medical-education-technology-and-the-millennial-learner
#2
REVIEW
Laura Hopkins, Brittany S Hampton, Jodi F Abbott, Sandra D Buery-Joyner, Latasha B Craig, John L Dalrymple, David A Forstein, Scott C Graziano, Margaret L Mckenzie, Archana Pradham, Abigail Wolf, Sarah M Page-Ramsey
This article, from the "To The Point" series prepared by the Association of Professors of Gynecology and Obstetrics Undergraduate Medical Education Committee, provides an overview of the characteristics of Millennials, and describes how medical educators can customize and reframe their curricula and teaching methods to maximize Millennial learning. A literature search was performed to identify articles on generational learning. We summarize the importance of understanding the attitudes, ideas, and priorities of Millennials in order to tailor educational methods to stimulate and enhance learning...
June 6, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28578592/adjunctive-minocycline-treatment-for-major-depressive-disorder-a-proof-of-concept-trial
#3
Olivia M Dean, Buranee Kanchanatawan, Melanie Ashton, Mohammadreza Mohebbi, Chee Hong Ng, Michael Maes, Lesley Berk, Atapol Sughondhabirom, Sookjaroen Tangwongchai, Ajeet B Singh, Helen McKenzie, Deidre J Smith, Gin S Malhi, Nathan Dowling, Michael Berk
OBJECTIVE: Conventional antidepressant treatments result in symptom remission in 30% of those treated for major depressive disorder, raising the need for effective adjunctive therapies. Inflammation has an established role in the pathophysiology of major depressive disorder, and minocycline has been shown to modify the immune-inflammatory processes and also reduce oxidative stress and promote neuronal growth. This double-blind, randomised, placebo-controlled trial examined adjunctive minocycline (200 mg/day, in addition to treatment as usual) for major depressive disorder...
June 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28561887/reconciling-patient-and-provider-priorities-for-improving-the-care-of-critically-ill-patients-a-consensus-method-and-qualitative-analysis-of-decision-making
#4
Emily McKenzie, Melissa L Potestio, Jamie M Boyd, Daniel J Niven, Rebecca Brundin-Mather, Sean M Bagshaw, Henry T Stelfox
BACKGROUND: Providers have traditionally established priorities for quality improvement; however, patients and their family members have recently become involved in priority setting. Little is known about how to reconcile priorities of different stakeholder groups into a single prioritized list that is actionable for organizations. OBJECTIVE: To describe the decision-making process for establishing consensus used by a diverse panel of stakeholders to reconcile two sets of quality improvement priorities (provider/decision maker priorities n=9; patient/family priorities n=19) into a single prioritized list...
May 31, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28559667/inter-rater-reliability-of-the-mckenzie-system-of-mechanical-diagnosis-and-therapy-in-the-examination-of-the-knee
#5
Sean Willis, Richard Rosedale, Ravi Rastogi, Shawn M Robbins
OBJECTIVE: The McKenzie System of Mechanical Diagnosis and Therapy (MDT) is a widely used method of classification and management of musculoskeletal problems. Although MDT has been investigated for its reliability and efficacy in the management of spinal pain, few studies have evaluated the system when applying it to musculoskeletal problems in the extremities, in particular the knee. The purpose of this study was to investigate the inter-rater reliability of MDT when classifying clinical vignettes describing patients with musculoskeletal knee pain...
May 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28551398/regional-variation-in-skeletal-muscle-and-adipose-tissue-fdg-uptake-using-pet-ct-and-their-relation-to-bmi
#6
Marcus D Goncalves, Judith Green-McKenzie, Abass Alavi, Drew A Torigian
RATIONALE AND OBJECTIVES: Skeletal muscle metabolism is a primary contributor to whole-body energy expenditure. Currently, methods to measure changes in skeletal muscle metabolism in vivo are limited. Our objectives were to characterize the regional variation in skeletal muscle and adipose tissue (AT) FDG uptake as a surrogate for glycolytic metabolism using (18)F-2-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in healthy men and to correlate these findings to body mass index (BMI)...
May 24, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28535818/rapid-evaporative-ionisation-mass-spectrometry-of-electrosurgical-vapours-for-the-identification-of-breast-pathology-towards-an-intelligent-knife-for-breast-cancer-surgery
#7
Edward R St John, Julia Balog, James S McKenzie, Merja Rossi, April Covington, Laura Muirhead, Zsolt Bodai, Francesca Rosini, Abigail V M Speller, Sami Shousha, Rathi Ramakrishnan, Ara Darzi, Zoltan Takats, Daniel R Leff
BACKGROUND: Re-operation for positive resection margins following breast-conserving surgery occurs frequently (average = 20-25%), is cost-inefficient, and leads to physical and psychological morbidity. Current margin assessment techniques are slow and labour intensive. Rapid evaporative ionisation mass spectrometry (REIMS) rapidly identifies dissected tissues by determination of tissue structural lipid profiles through on-line chemical analysis of electrosurgical aerosol toward real-time margin assessment...
May 23, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28530116/autism-and-attachment-difficulties-overlap-of-symptoms-implications-and-innovative-solutions
#8
Rebecca McKenzie, Rudi Dallos
This article explores overlap of symptoms between autism and attachment difficulties and suggests innovative solutions based on formulation. Currently, clinicians express difficulties in differentiating between these conditions contributing to misdiagnosis. Research into the prevalence of attachment difficulties among children with autism often fails to reflect detailed knowledge of attachment theory. Consequently, studies in this area employ questionable modifications to attachment measures and methods of analysis...
May 1, 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/28507724/deep-learning-and-3d-desi-imaging-reveal-the-hidden-metabolic-heterogeneity-of-cancer
#9
Paolo Inglese, James S McKenzie, Anna Mroz, James Kinross, Kirill Veselkov, Elaine Holmes, Zoltan Takats, Jeremy K Nicholson, Robert C Glen
Visual inspection of tumour tissues does not reveal the complex metabolic changes that differentiate cancer and its sub-types from healthy tissues. Mass spectrometry imaging, which quantifies the underlying chemistry, represents a powerful tool for the molecular exploration of tumour tissues. A 3-dimensional topological description of the chemical properties of the tumour permits the formulation of hypotheses about the biological composition and interactions and the possible causes of its heterogeneous structure...
May 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28496219/the-flipped-classroom-for-pre-clinical-dental-skills-teaching-a-reflective-commentary
#10
A J Crothers, J Bagg, R McKenzie
A Flipped Classroom method for teaching of adult practical pre-clinical dental skills was introduced to the BDS curriculum in Glasgow during the 2015/2016 academic session. This report provides a commentary of the first year of employing this method - from the identification of the need to optimise teaching resources, through the planning, implementation and development of the method, with an early indication of performance.
May 12, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28483654/validity-of-robot-based-assessments-of-upper-extremity-function
#11
Alison McKenzie, Lucy Dodakian, Jill See, Vu Le, Erin Burke Quinlan, Claire Bridgford, Daniel Head, Vy L Han, Steven C Cramer
OBJECTIVE: To examine the validity of 5 robot-based assessments of arm motor function post-stroke. DESIGN: Cross sectional. SETTING: Outpatient clinical research center. PARTICIPANTS: Volunteer sample of 40 participants, age >18 years, 3-6 months post-stroke, with arm motor deficits that had plateaued. INTERVENTION: None. MAIN OUTCOME MEASURES: Clinical standards included the Fugl-Meyer Arm Motor Scale (FMA), and 5 secondary motor outcomes: hand/wrist subsection of the FMA; Action Research Arm Test (ART); Box & Blocks test (B/B); hand subscale of Stroke Impact Scale-2 (SIS); and the Barthel Index (BI)...
May 5, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28446138/assessing-the-complexity-of-interventions-within-systematic-reviews-development-content-and-use-of-a-new-tool-icat_sr
#12
Simon Lewin, Maggie Hendry, Jackie Chandler, Andrew D Oxman, Susan Michie, Sasha Shepperd, Barnaby C Reeves, Peter Tugwell, Karin Hannes, Eva A Rehfuess, Vivien Welch, Joanne E Mckenzie, Belinda Burford, Jennifer Petkovic, Laurie M Anderson, Janet Harris, Jane Noyes
BACKGROUND: Health interventions fall along a spectrum from simple to more complex. There is wide interest in methods for reviewing 'complex interventions', but few transparent approaches for assessing intervention complexity in systematic reviews. Such assessments may assist review authors in, for example, systematically describing interventions and developing logic models. This paper describes the development and application of the intervention Complexity Assessment Tool for Systematic Reviews (iCAT_SR), a new tool to assess and categorise levels of intervention complexity in systematic reviews...
April 26, 2017: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/28433432/ascende-rt-an-analysis-of-treatment-related-morbidity-for-a-randomized-trial-comparing-a-low-dose-rate-brachytherapy-boost-with-a-dose-escalated-external-beam-boost-for-high-and-intermediate-risk-prostate-cancer
#13
Sree Rodda, Scott Tyldesley, W James Morris, Mira Keyes, Ross Halperin, Howard Pai, Michael McKenzie, Graeme Duncan, Gerard Morton, Jeremy Hamm, Nevin Murray
PURPOSE: To report the genitourinary (GU) and gastrointestinal (GI) morbidity and erectile dysfunction in a randomized trial comparing 2 methods of dose escalation for high- and intermediate-risk prostate cancer. METHODS AND MATERIALS: ASCENDE-RT (Androgen Suppression Combined with Elective Nodal and Dose Escalated Radiation Therapy) enrolled 398 men, median age 68 years, who were then randomized to either a standard arm that included 12 months of androgen deprivation therapy and pelvic irradiation to 46 Gy followed by a dose-escalated external beam radiation therapy (DE-EBRT) boost to 78 Gy, or an experimental arm that substituted a low-dose-rate prostate brachytherapy (LDR-PB) boost...
January 6, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28422893/do-concussive-symptoms-really-resolve-in-young-children
#14
Coco O Bernard, Jennie L Ponsford, Audrey McKinlay, Dean McKenzie, David Krieser
OBJECTIVES: To examine the frequency and nature of postconcussive symptoms (PCSs) and behavioral outcomes in young children following mild traumatic brain injury (mTBI) or concussion. SETTING: Emergency department. PARTICIPANTS: Children aged 2 to 12 years presenting with either a concussion or minor bodily injury (control). OUTCOME MEASUREMENT: Parent ratings of PCS were obtained within 72 hours of injury, at 1 week, and 1, 2, and 3 months postinjury using a comprehensive PCS checklist...
April 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28414020/modifying-alcohol-consumption-to-reduce-obesity-macro-development-and-feasibility-trial-of-a-complex-community-based-intervention-for-men
#15
Iain K Crombie, Kathryn B Cunningham, Linda Irvine, Brian Williams, Falko F Sniehotta, John Norrie, Ambrose Melson, Claire Jones, Andrew Briggs, Peter M Rice, Marcus Achison, Andrew McKenzie, Elena Dimova, Peter W Slane
BACKGROUND: Obese men who consume alcohol are at a greatly increased risk of liver disease; those who drink > 14 units of alcohol per week have a 19-fold increased risk of dying from liver disease. OBJECTIVES: To develop an intervention to reduce alcohol consumption in obese men and to assess the feasibility of a randomised controlled trial (RCT) to investigate its effectiveness. DESIGN OF THE INTERVENTION: The intervention was developed using formative research, public involvement and behaviour change theory...
April 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28386217/genome-wide-association-study-gwas-between-attention-deficit-hyperactivity-disorder-adhd-and-obsessive-compulsive-disorder-ocd
#16
McKenzie L Ritter, Wei Guo, Jack F Samuels, Ying Wang, Paul S Nestadt, Janice Krasnow, Benjamin D Greenberg, Abby J Fyer, James T McCracken, Daniel A Geller, Dennis L Murphy, James A Knowles, Marco A Grados, Mark A Riddle, Steven A Rasmussen, Nicole C McLaughlin, Erika L Nurmi, Kathleen D Askland, Bernadette Cullen, John Piacentini, David L Pauls, Joseph Bienvenu, Evelyn Stewart, Fernando S Goes, Brion Maher, Ann E Pulver, Manuel Mattheisen, Ji Qian, Gerald Nestadt, Yin Yao Shugart
Objective: The aim of this study was to identify any potential genetic overlap between attention deficit hyperactivity disorder (ADHD) and obsessive compulsive disorder (OCD). We hypothesized that since these disorders share a sub-phenotype, they may share common risk alleles. In this manuscript, we report the overlap found between these two disorders. Methods: A meta-analysis was conducted between ADHD and OCD, and polygenic risk scores (PRS) were calculated for both disorders. In addition, a protein-protein analysis was completed in order to examine the interactions between proteins; p-values for the protein-protein interaction analysis was calculated using permutation...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28382790/fenton-raft-polymerization-an-on-demand-chain-growth-method
#17
Amin Reyhani, Thomas G McKenzie, Hadi Ranji-Burachaloo, Qiang Fu, Greg G Qiao
Fine control over the architecture and/or microstructure of synthetic polymers is fast becoming a reality owing to the development of efficient and versatile polymerization techniques and conjugation reactions. However, the transition of these syntheses to automated, programmable, and high-throughput operating systems is a challenging step needed to translate the vast potential of precision polymers into machine-programmable polymers for biological and functional applications. Chain-growth polymerizations are particularly appealing for their ability to form structurally and chemically well-defined macromolecules through living/controlled polymerization techniques...
April 6, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28364621/-working-towards-being-ready-a-grounded-theory-study-of-how-practising-midwives-maintain-their-ongoing-competence-to-practise-their-profession
#18
Susan Calvert, Elizabeth Smythe, Barbara McKenzie-Green
OBJECTIVE: to present a grounded theory research study explaining how New Zealand midwives maintain their ongoing competence to practise their profession. DESIGN: grounded theory, an interpretive emergent research methodology was used to examine the process of maintaining competence in midwifery practice. SETTING: New Zealand urban and rural practice settings. PARTICIPANTS: twenty-six midwives from across New Zealand were interviewed and asked about maintaining their competence to practise...
March 14, 2017: Midwifery
https://www.readbyqxmd.com/read/28293693/changing-hands-persistent-alterations-to-body-image-following-brief-exposure-to-multisensory-distortions
#19
A Treshi-Marie Perera, Roger Newport, Kirsten J McKenzie
The dynamic flexibility of body representation has been highlighted through numerous lines of research that range from clinical studies reporting disorders of body ownership, to experimentally induced somatic illusions that have provided evidence for the embodiment of manipulated representations and even fake limbs. While most studies have reported that enlargement of body parts alters somatic perception, and that these can be more readily embodied, shrunken body parts have not been found to consistently alter somatic experiences, perhaps due to reduced feelings of ownership over smaller body parts...
June 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28281192/reliability-of-thermodilution-derived-cardiac-output-with-different-operator-characteristics
#20
Scott C McKenzie, Kimble Dunster, Wandy Chan, Martin R Brown, David G Platts, George Javorsky, Chris Anstey, Shaun D Gregory
Cardiac output (CO) is commonly measured using the thermodilution technique at the time of right heart catheterisation (RHC). However inter-operator variability, and the operator characteristics which may influence that, has not been quantified. Therefore, this study aimed to assess inter-operator variability with the thermodilution technique using a mock circulation loop (MCL) with calibrated flow sensors. Participants were blinded and asked to determine 4 levels of CO using the thermodilution technique, which was compared with the MCL calibrated flow sensors...
March 9, 2017: Journal of Clinical Monitoring and Computing
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