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https://www.readbyqxmd.com/read/29778183/high-genetic-diversity-of-extended-spectrum-%C3%AE-lactamases-producing-escherichia-coli-in-feces-of-horses
#1
Syndia Sadikalay, Yann Reynaud, Stéphanie Guyomard-Rabenirina, Mélanie Falord, Célia Ducat, Laetitia Fabre, Simon Le Hello, Antoine Talarmin, Séverine Ferdinand
Extended-spectrum beta-lactamases (ESBLs), especially those of the CTX-M type, represent a major public health problem throughout the world. Although the carriage of ESBL-producing Enterobacteriaceae (EPE) in feces of horses is now well recognized, little is known about the diversity of EPE after treatment of horses with antibiotics. We undertook this study to assess and follow the diversity of EP Escherichia coli isolated from horses after antibiotic treatment for an infection. Fecal samples from two horses treated and two that were untreated were tested for the presence of EPE on different days...
June 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29763359/are-sleep-alterations-the-cause-of-icu-delirium
#2
Arnaud W Thille, Faustine Reynaud, Damien Marie, Stéphanie Barrau, Ludivine Rousseau, Christophe Rault, Xavier Drouot
No abstract text is available yet for this article.
May 15, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29750947/glaucoma-specialist-optic-disc-margin-rim-margin-and-rim-width-discordance-in-glaucoma-and-glaucoma-suspect-eyes
#3
Seung Woo Hong, Helen Koenigsman, Ruojin Ren, Hongli Yang, Stuart K Gardiner, Juan Reynaud, Robert M Kinast, Steven L Mansberger, Brad Fortune, Shaban Demirel, Claude F Burgoyne
PURPOSE: To quantify the variability of 5 glaucoma specialists' optic disc margin (DM), rim margin (RM) and rim width (RW) estimates. DESIGN: Inter-Observer Reliability analysis. METHODS: Clinicians viewed stereo-photos from 214 subjects with glaucoma or ocular hypertension and digitally marked the DM and RM. For each photo, the centroid of each clinician's DM was calculated, and an averaged DMcentroid was determined. The axis between the DMcentroid and the fovea was used to establish twelve 30° sectors...
May 8, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29745715/tools-don-t-and-won-t-make-the-man-a-cognitive-look-at-the-future
#4
François Osiurak, Jordan Navarro, Emanuelle Reynaud, Gauthier Thomas
The question of whether tools erase cognitive and physical interindividual differences has been surprisingly overlooked in the literature. Yet if technology is profusely available in a near or far future, will we be equal in our capacity to use it? We sought to address this unexplored, fundamental issue, asking 200 participants to perform 3 physical (e.g., fine manipulation) and 3 cognitive tasks (e.g., calculation) in both non-tool-use and tool-use conditions. Here we show that tools do not erase but rather extend our intrinsic physical and cognitive skills...
May 2018: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/29723568/family-history-is-under-estimated-in-children-with-isolated-hypospadias-a-french-multicenter-report-of-88-families
#5
Margot Ollivier, Francoise Paris, Pascal Philibert, Sarah Garnier, Amandine Coffy, Nadège Fauconnet-Servant, Mirna Haddad, Jean Michel Guys, Rachel Reynaud, Alice Faure, Thierry Merrot, Kathy Wagner, Jean Bréaud, Jean Stéphane Valla, Eric Dobremez, Laura Gaspari, Jean-Pierre Daures, Charles Sultan, Nicolas Kalfa
Whereas familial forms of complex disorders/differences of sex development have been widely reported, data regarding isolated hypospadias are sparse and a family history is thought to be less frequent. We aimed 1-to determine the frequency of hypospadias in families of hypospadiac boys 2-to determine if theses familial forms exhibit a particular phenotype 3-to evaluate the prevalence of genetic defects of the main candidate genes. A prospective inclusion of 395 hypospadiac boys screened for family history with a standardized questionnaire, extensive clinical description, family tree and sequencing of AR, SF1, SRD5A2 and MAMLD1 was performed...
April 30, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29706418/seminal-plasma-differentially-alters-the-resistance-of-dog-ram-and-boar-spermatozoa-to-hypotonic-stress
#6
Guillaume Tsikis, Karine Reynaud, Stéphane Ferchaud, Xavier Druart
During ejaculation and the deposition in the female genital tract, spermatozoa undergo hypo-osmotic stress and need to withstand it for optimal fertility. Resistance to hypo-osmotic stress may be affected by the interaction of the spermatozoa with seminal fluid components. The hypo-osmotic resistance of epididymal and ejaculated spermatozoa from dogs, rams and boars was assessed by flow cytometric measurement of sperm viability after incubation in NaCl solutions with osmolalities ranging from 0 to 300 mmol/kg...
February 2, 2018: Animal Reproduction Science
https://www.readbyqxmd.com/read/29704221/erratum-to-eg-vegf-maintenance-over-early-gestation-to-develop-a-pregnancy-induced-hypertensive-animal-model
#7
Déborah Reynaud, Frédéric Sergent, Roland Abi Nahed, Sophie Brouillet, Mohamed Benharouga, Nadia Alfaidy
No abstract text is available yet for this article.
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29700855/long-term-extra-pulmonary-comorbidities-after-lung-transplantation-in-cystic-fibrosis-update-of-specificities
#8
REVIEW
Sabine Jardel, Quitterie Reynaud, Isabelle Durieu
Lung transplantation (LT) is the standard therapeutic option for cystic fibrosis (CF) patients with end-stage lung disease. Both conditions lead to extra-respiratory complications, such as diabetes, renal insufficiency, bone disease, and cancer. The purpose of the present paper is to provide an update of the non-respiratory comorbidities following LT in adult patients with CF and their specificities regarding their multi-systemic underlying condition despite their younger age compared to other patients undergoing LT...
April 26, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29695229/rituximab-for-auto-immune-alveolar-proteinosis-a-real-life-cohort-study
#9
Berenice Soyez, Raphael Borie, Cedric Menard, Jacques Cadranel, Leonidas Chavez, Vincent Cottin, Emmanuel Gomez, Sylvain Marchand-Adam, Sylvie Leroy, Jean-Marc Naccache, Hilario Nunes, Martine Reynaud-Gaubert, Laurent Savale, Abdellatif Tazi, Lidwine Wemeau-Stervinou, Marie-Pierre Debray, Bruno Crestani
BACKGROUND: Whole lung lavage is the current standard therapy for pulmonary alveolar proteinosis (PAP) that is characterized by the alveolar accumulation of surfactant. Rituximab showed promising results in auto-immune PAP (aPAP) related to anti-GM-CSF antibody. METHODS: We aimed to assess efficacy of rituximab in aPAP in real life and all patients with aPAP in France that received rituximab were retrospectively analyzed. RESULTS: Thirteen patients were included...
April 25, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29686083/unexpected-metabolic-disorders-induced-by-endocrine-disruptors-in-xenopus-tropicalis-provide-new-lead-for-understanding-amphibian-decline
#10
Christophe Regnault, Marie Usal, Sylvie Veyrenc, Karine Couturier, Cécile Batandier, Anne-Laure Bulteau, David Lejon, Alexandre Sapin, Bruno Combourieu, Maud Chetiveaux, Cédric Le May, Thomas Lafond, Muriel Raveton, Stéphane Reynaud
Despite numerous studies suggesting that amphibians are highly sensitive to endocrine disruptors (EDs), both their role in the decline of populations and the underlying mechanisms remain unclear. This study showed that frogs exposed throughout their life cycle to ED concentrations low enough to be considered safe for drinking water, developed a prediabetes phenotype and, more commonly, a metabolic syndrome. Female Xenopus tropicalis exposed from tadpole stage to benzo( a )pyrene or triclosan at concentrations of 50 ng⋅L-1 displayed glucose intolerance syndrome, liver steatosis, liver mitochondrial dysfunction, liver transcriptomic signature, and pancreatic insulin hypersecretion, all typical of a prediabetes state...
April 23, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29684175/aminoglycoside-exposure-and-renal-function-before-lung-transplantation-in-adult-cystic-fibrosis-patients
#11
Etienne Novel-Catin, Solenne Pelletier, Quitterie Reynaud, Raphaele Nove-Josserand, Stephane Durupt, Laurence Dubourg, Isabelle Durieu, Denis Fouque
Background: Patients with cystic fibrosis (CF) are at risk of kidney injury even before undergoing lung transplantation, because of prolonged exposure to aminoglycosides (AGs), chronic dehydration and complications of diabetes mellitus. The usual equations estimating the glomerular filtration rate (GFR), such as Cockcroft-Gault and Modification of Diet in Renal Disease, are not adapted to the CF population due to patients' low body weight and reduced muscle mass. The aim of this study was to precisely measure GFR in adult CF patients and to see whether repeated AG treatment would impair renal function before lung transplantation...
April 18, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29650388/evaluation-at-3-years-of-concurrent-bevacizumab-and-radiotherapy-for-breast-cancer-results-of-a-prospective-study
#12
A Dautruche, L Belin, P Cottu, P Bontemps, C Lemanski, B de la Lande, P Baumann, F Missohou, C Lévy, K Peignaux, A Reynaud-Bougnoux, F Denis, A Gobillion, V Pernin, Y Kirova
PURPOSE: To determine the 3 years late toxicity among patients with non-metastatic breast cancer who received concurrent bevacizumab and locoregional radiotherapy. MATERIAL AND METHODS: This is a single-arm, multicentre, prospective study, of the toxicity of adjuvant concomitant association of bevacizumab and radiotherapy in patients with breast cancer. Toxicity was assessed by the Common Terminology Criteria for Adverse Events version 3.0 during the radiotherapy and follow-up clinics at 12 and 36 months after its completion...
April 9, 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/29628135/lung-transplantation-for-scleroderma-lung-disease-an-international-multicenter-observational-cohort-study
#13
Pauline Pradère, Igor Tudorache, Jesper Magnusson, Laurent Savale, Olivier Brugiere, Benoît Douvry, Martine Reynaud-Gaubert, Johanna Claustre, Aurélie Le Borgne, Are M Holm, Hans Henrik Schultz, Christiane Knoop, Laurent Godinas, Andrew J Fisher, Sandrine Hirschi, Jens Gottlieb, Jérôme Le Pavec
BACKGROUND: Due to its multisystemic nature, scleroderma is considered a relative contraindication to lung transplantation at many centers. However, recent studies suggest similar post-transplant outcomes in patients with scleroderma compared to those with other causes of interstitial lung disease (ILD). Furthermore, it remains unknown whether scleroderma-associated pulmonary arterial hypertension (PAH) influences post-transplant outcomes. Our objective in this study was to assess the indications, survival, and prognostic factors of lung or heart-lung transplantation for scleroderma lung disease...
March 15, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29627410/-intrauterine-device-and-pelvic-inflammatory-disease-myth-or-reality
#14
T Straub, M Reynaud, M Yaron
INTRODUCTION: Intrauterine device (IUD) is a reliable contraceptive method that is long term reversible, and well tolerated. Numerous studies prove its efficiency and report rare complications that are attributed to it. However, its use is limited due to fear that it can cause a pelvic inflammatory disease (PID). This is based on historical data on infections related to the "Dalkon Shield", which was removed from the market in 1974. METHOD: The analyzed articles were extracted from PUBMED database between 2000 and 2016...
April 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29623880/serum-gh-concentration-must-now-be-expressed-in-mass-units-in-france-like-in-the-rest-of-the-world
#15
Philippe Chanson, Rachel Reynaud, Régis Coutant, Agnès Linglart, Marc Nicolino, Patrice Rodien, Françoise Borson-Chazot, Antoine Tabarin, Yves Le Bouc, Marie-Liesse Piketty, Anne-Sophie Gauchez, Didier Chevenne, Dominique Porquet, Jean-Claude Souberbielle
No abstract text is available yet for this article.
April 1, 2018: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/29609396/control-of-the-coherence-behavior-in-a-sfg-interferometer-through-the-multipump-phases-command
#16
P Darré, L Lehmann, L Grossard, L Delage, F Reynaud
In this paper, we report on a novel method to control the coherence behavior in a sum frequency generation interferometer powered by two independent pump lines. At the output of the interferometer, the two incoherent fringe patterns must be superimposed to maximize the contrast. The first step consists in canceling the differential group delay. The second one uses the phase control on one pump to synchronize the fringe patterns. This innovative method is experimentally demonstrated with a setup involving a 1544 nm signal and two pump lines around 1064 nm leading to a converted signal around 630 nm...
March 19, 2018: Optics Express
https://www.readbyqxmd.com/read/29594052/parathyroid-hormone-assays-following-total-thyroidectomy-is-there-a-predictive-value
#17
Camille Galy-Bernadoy, Benjamin Lallemant, Guillaume Chambon, Huy Trang Pham, Christophe Reynaud, Caroline Alovisetti, Quentin Bonduelle, Anne Marie Guedj, Serge Lumbroso, David-Paul De Brauwere
Objectives: Parathyroid hormone (PTH) is a risk marker for hypoparathyroidism (hypoPTH). This study aimed to determine the predictive values of early PTH assays carried out at the moment of skin closure (PTH SC), to establish a treatment algorithm, identifying two threshold values. We assessed the reproducibility of this approach with two different immunoassay kits (hypoPTH) after total thyroidectomy, but its practical application is not consensual. Study Design: We conducted a prospective descriptive study, including all patients who underwent a total thyroidectomy between March 2012 and November 2013...
January 2018: European Thyroid Journal
https://www.readbyqxmd.com/read/29577406/quantifying-myofiber-integrity-using-diffusion-mri-and-random-permeable-barrier-modeling-in-skeletal-muscle-growth-and-duchenne-muscular-dystrophy-model-in-mice
#18
Kerryanne V Winters, Olivier Reynaud, Dmitry S Novikov, Els Fieremans, Sungheon Gene Kim
PURPOSE: To measure the microstructural changes during skeletal muscle growth and progressive pathologies using the random permeable model with diffusion MRI, and compare findings to conventional imaging modalities such as three-point Dixon and T2 imaging. METHODS: In vivo and ex vivo DTI experiments with multiple diffusion times (20-700 ms) were completed on wild-type (n = 22) and muscle-dystrophic mdx mice (n = 8) at various developmental time points. The DTI data were analyzed with the random permeable model framework that provides estimates of the unrestricted diffusion coefficient (D0 ), membrane surface-to-volume ratio (S/V), and membrane permeability (κ)...
March 25, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29571601/high-circulating-cd4-cd25-hi-foxp3-t-cell-sub-population-early-after-lung-transplantation-is-associated-with-development-of-bronchiolitis-obliterans-syndrome
#19
Maxim Durand, Philippe Lacoste, Richard Danger, Lola Jacquemont, Carole Brosseau, Eugénie Durand, Gaelle Tilly, Jennifer Loy, Aurore Foureau, Pierre-Joseph Royer, Adrien Tissot, Antoine Roux, Martine Reynaud-Gaubert, Romain Kessler, Sacha Mussot, Claire Dromer, Olivier Brugière, Jean François Mornex, Romain Guillemain, Johanna Claustre, Nicolas Degauque, Antoine Magnan, Sophie Brouard
BACKGROUND: Chronic bronchiolitis obliterans syndrome (BOS) remains a major limitation for long-term survival after lung transplantation. The immune mechanisms involved and predictive biomarkers have yet to be identified. The purpose of this study was to determine whether peripheral blood T-lymphocyte profile could predict BOS in lung transplant recipients. METHODS: An in-depth profiling of CD4+ and CD8+ T cells was prospectively performed on blood cells from stable (STA) and BOS patients with a longitudinal follow-up...
March 20, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29563891/how-our-cognition-shapes-and-is-shaped-by-technology-a-common-framework-for-understanding-human-tool-use-interactions-in-the-past-present-and-future
#20
REVIEW
François Osiurak, Jordan Navarro, Emanuelle Reynaud
Over the evolution, humans have constantly developed and improved their technologies. This evolution began with the use of physical tools, those tools that increase our sensorimotor abilities (e.g., first stone tools, modern knives, hammers, pencils). Although we still use some of these tools, we also employ in daily life more sophisticated tools for which we do not systematically understand the underlying physical principles (e.g., computers, cars). Current research is also turned toward the development of brain-computer interfaces directly linking our brain activity to machines (i...
2018: Frontiers in Psychology
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