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https://www.readbyqxmd.com/read/28738420/variation-in-the-three-dimensional-histomorphometry-of-the-normal-human-optic-nerve-head-with-age-and-race-lamina-cribrosa-and-peripapillary-scleral-thickness-and-position
#1
Christopher A Girkin, Massimo A Fazio, Hongli Yang, Juan Reynaud, Claude F Burgoyne, Brandon Smith, Lan Wang, J Crawford Downs
Purpose: This study quantified the thickness and depth of the lamina cribrosa (LC) and peripapillary scleral thickness in high-resolution three-dimensional (3D) fluorescent reconstructions of the optic nerve head (ONH) in eyes from donors of African (AD) and European descent (ED). Methods: A total of 64 eyes (45 ED, 19 AD) from 51 normal donors were obtained within 6 hours of death and fixed at 10 mm Hg of pressure. The optic nerve head was trephined from the globe and digitally reconstructed at 1...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28729708/new-mycobacterium-tuberculosis-beijing-clonal-complexes-in-china-revealed-by-phylogenetic-and-bayesian-population-structure-analyses-of-24-loci-miru-vntrs
#2
Chao Zheng, Yann Reynaud, Changsong Zhao, Thierry Zozio, Song Li, Dongxia Luo, Qun Sun, Nalin Rastogi
Beijing lineage of Mycobacterium tuberculosis constitutes the most predominant lineage in East Asia. Beijing epidemiology, evolutionary history, genetics are studied in details for years revealing probable origin from China followed by worldwide expansion, partially linked to higher mutation rate, hypervirulence, drug-resistance, and association with cases of mixed infections. Considering huge amount of data available for 24-loci Mycobacterial Interspersed Repetitive Units-Variable Number of Tandem Repeats, we performed detailed phylogenetic and Bayesian population structure analyses of Beijing lineage strains in mainland China and Taiwan using available 24-loci MIRU-VNTR data extracted from publications or the SITVIT2 database (n = 1490)...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28728170/a-normative-data-set-for-the-clinical-assessment-of-achromatic-and-chromatic-contrast-sensitivity-using-a-qcsf-approach
#3
Yeon Jin Kim, Alexandre Reynaud, Robert F Hess, Kathy T Mullen
Purpose: The measurement of achromatic sensitivity has been an important tool for monitoring subtle changes in vision as the result of disease or response to therapy. In this study, we aimed to provide a normative data set for achromatic and chromatic contrast sensitivity functions within a common cone contrast space using an abbreviated measurement approach suitable for clinical practice. In addition, we aimed to provide comparisons of achromatic and chromatic binocular summation across spatial frequency...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28717190/interocular-contrast-difference-drives-illusory-3d-percept
#4
Alexandre Reynaud, Robert F Hess
Any processing delay between the two eyes can result in illusory 3D percepts for moving objects because of either changes in the pure disparities over time for disparity sensors or by changes to sensors that encode motion/disparity conjointly. This is demonstrated by viewing a fronto-parallel pendulum through a neutral density (ND) filter placed over one eye, resulting in the illusory 3D percept of the pendulum following an elliptical orbit in depth, the so-called Pulfrich phenomenon. Here we use a paradigm where a cylinder rotating in depth, defined by moving Gabor patches is presented at different interocular phases, generating strong to ambiguous depth percepts...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28716686/sedative-and-cardiovascular-effects-of-intranasal-or-intramuscular-dexmedetomidine-in-healthy-dogs
#5
Fabiana Micieli, Bruna Santangelo, Fabiana Reynaud, Alessandro Mirra, Giusy Napoleone, Giovanni Della Valle, Karine G Portier, Giancarlo Vesce
OBJECTIVE: To compare the clinical effects and sedation scores following either intranasal (IN) or intramuscular (IM) administration of dexmedetomidine in dogs. STUDY DESIGN: Prospective, blinded, randomized, clinical study. ANIMALS: A total of 20 client-owned dogs scheduled for noninvasive diagnostic procedures. METHODS: Dogs were allocated to be administered dexmedetomidine 0.02 mg kg(-1) IN (IN group) or IM (IM group)...
April 5, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28711791/labeled-azospirillum-brasilense-wild-type-and-excretion-ammonium-strains-in-association-with-barley-roots
#6
Adrian Richard Schenberger Santos, Rafael Mazer Etto, Rafaela Wiegand Furmam, Denis Leandro de Freitas, Karina Freire d'Eça Nogueira Santos, Emanuel Maltempi de Souza, Fábio de Oliveira Pedrosa, Ricardo Antônio Ayub, Maria Berenice Reynaud Steffens, Carolina Weigert Galvão
Soil bacteria colonization in plants is a complex process, which involves interaction between many bacterial characters and plant responses. In this work, we labeled Azospirillum brasilense FP2 (wild type) and HM053 (excretion-ammonium) strains by insertion of the reporter gene gusA-kanamycin into the dinitrogenase reductase coding gene, nifH, and evaluated bacteria colonization in barley (Hordeum vulgare). In addition, we determined inoculation effect based on growth promotion parameters. We report an uncommon endophytic behavior of A...
July 4, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28711222/retrospective-observational-study-of-french-patients-with-cystic-fibrosis-and-a-gly551asp-cftr-mutation-after-1-and-2years-of-treatment-with-ivacaftor-in-a-real-world-setting
#7
Dominique Hubert, Clémence Dehillotte, Anne Munck, Valérie David, Jinmi Baek, Laurent Mely, Stéphane Dominique, Sophie Ramel, Isabelle Danner Boucher, Sylvaine Lefeuvre, Quitterie Reynaud, Virginie Colomb-Jung, Prissile Bakouboula, Lydie Lemonnier
BACKGROUND: Ivacaftor has been shown to improve lung function and body weight in patients with CF and a gating mutation. Real-world evaluation is warranted to examine its safety and effectiveness over the long term. METHODS: A retrospective observational multicentre study collected clinical data in the year before and the 2years after ivacaftor initiation in patients with CF and a Gly551Asp-CFTR mutation. RESULTS: Fifty-seven patients were included...
July 12, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28686788/influence-of-physiological-noise-on-accelerated-2d-and-3d-resting-state-functional-mri-data-at-7%C3%A2-t
#8
Olivier Reynaud, João Jorge, Rolf Gruetter, José P Marques, Wietske van der Zwaag
PURPOSE: Physiological noise often dominates the blood-oxygen level-dependent (BOLD) signal fluctuations in high-field functional MRI (fMRI) data. Therefore, to optimize fMRI protocols, it becomes crucial to investigate how physiological signal fluctuations impact various acquisition and reconstruction schemes at different acquisition speeds. In particular, further differences can arise between 2D and 3D fMRI acquisitions due to different encoding strategies, thereby impacting fMRI sensitivity in potentially significant ways...
July 7, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28674462/a-global-meta-analysis-of-the-value-of-ecosystem-services-provided-by%C3%A2-lakes
#9
Arnaud Reynaud, Denis Lanzanova
This study presents the first meta-analysis on the economic value of ecosystem services delivered by lakes. A worldwide data set of 699 observations drawn from 133 studies combines information reported in primary studies with geospatial data. The meta-analysis explores antagonisms and synergies between ecosystem services. This is the first meta-analysis to incorporate simultaneously external geospatial data and ecosystem service interactions. We first show that it is possible to reliably predict the value of ecosystem services provided by lakes based on their physical and geographic characteristics...
July 2017: Ecological Economics: the Journal of the International Society for Ecological Economics
https://www.readbyqxmd.com/read/28667881/grey-matter-density-changes-of-structures-involved-in-posttraumatic-stress-disorder-ptsd-after-recovery-following-eye-movement-desensitization-and-reprocessing-emdr-therapy
#10
Sarah Boukezzi, Myriam El Khoury-Malhame, Guillaume Auzias, Emmanuelle Reynaud, Pierre-François Rousseau, Emmanuel Richard, Xavier Zendjidjian, Jacques Roques, Nathalie Castelli, Nadia Correard, Valérie Guyon, Caroline Gellato, Jean-Claude Samuelian, Aida Cancel, Magali Comte, Marianne Latinus, Eric Guedj, Stéphanie Khalfa
Recovery of stress-induced structural alterations in Posttraumatic Stress Disorder (PTSD) remains largely unexplored. This study aimed to determine whether symptoms improvement is associated with grey matter (GM) density changes of brain structures involved in PTSD. Two groups of PTSD patients were involved in this study. The first group was treated with Eye Movement Desensitization and Reprocessing (EMDR) therapy and recovered from their symptoms (recovery group) (n = 11); Patients were scanned prior to therapy (T1), one week (T2) and five months after the end of therapy (T3)...
June 19, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28661494/assessing-phototoxicity-in-live-fluorescence-imaging
#11
P Philippe Laissue, Rana A Alghamdi, Pavel Tomancak, Emmanuel G Reynaud, Hari Shroff
Are the answers to biological questions obtained via live fluorescence microscopy substantially affected by phototoxicity? Although a single set of standards for assessing phototoxicity cannot exist owing to the breadth of samples and experimental questions associated with biological imaging, we need quantitative, practical assessments and reporting standards to ensure that imaging has a minimal impact on observed biological processes and sample health. Here we discuss the problem of phototoxicity in biology and suggest guidelines to improve its reporting and assessment...
June 29, 2017: Nature Methods
https://www.readbyqxmd.com/read/28660083/visual-plasticity-in-adults
#12
EDITORIAL
Jiawei Zhou, Zili Liu, Simon Clavagnier, Alexandre Reynaud, Fang Hou
No abstract text is available yet for this article.
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28648199/transformer-le-regard-social-sur-l%C3%A2-addiction
#13
Michel Reynaud
No abstract text is available yet for this article.
June 2017: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/28646623/pregnancy-outcome-in-women-with-cystic-fibrosis-related-diabetes
#14
Quitterie Reynaud, Stéphanie Poupon-Bourdy, Muriel Rabilloud, Lina Al Mufti, Christine Rousset Jablonski, Lydie Lemonnier, Raphaële Nove-Josserand, Sandrine Touzet, Isabelle Durieu
With increasing life expectancy more women with cystic fibrosis and diabetes mellitus become pregnant. We investigated how pre-gestational diabetes (cystic fibrosis related diabetes) influenced pregnancy outcome and the clinical status of these women MATERIAL AND METHODS: We analyzed all pregnancies reported to the French cystic fibrosis registry between 2001 and 2012, and compared forced expiratory volume (FEV1 ) and body mass index before and after pregnancy in women with and without pre-gestational diabetes having a first delivery RESULTS: A total 249 women delivered 314 infants...
June 24, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28636508/how-to-perform-stress-exercise-echocardiography-in-hypertrophic-cardiomyopathy
#15
Patricia Reant, Stephane Lafitte, Amelie Reynaud
No abstract text is available yet for this article.
March 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28630101/oviduct-extracellular-vesicles-protein-content-and-their-role-during-oviduct-embryo-cross-talk
#16
Carmen Alminana, Emilie Corbin, Guillaume Tsikis, Agostinho S Alcantara-Neto, Valérie Labas, Karine Reynaud, Laurent Galio, Rustem Uzbekov, Anastasiia S Garanina, Xavier Druart, Pascal Mermillod
Successful pregnancy requires an appropriate communication between the mother and the embryo. Recently, exosomes and microvesicles, both membrane-bound extracellular vesicles (EVs) present in the oviduct fluid have been proposed as key modulators of this unique cross-talk. However, little is known about their content and their role during oviduct-embryo dialogue. Given the known differences in secretions by in vivo and in vitro oviduct epithelial cells (OEC), we aimed at deciphering the oviduct EVs protein content from both sources...
June 19, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28625209/involvement-of-the-left-supramarginal-gyrus-in-manipulation-judgment-tasks-contributions-to-theories-of-tool-use
#17
Mathieu Lesourd, François Osiurak, Jordan Navarro, Emanuelle Reynaud
OBJECTIVES: Two theories of tool use, namely the gesture engram and the technical reasoning theories, make distinct predictions about the involvement of the left inferior parietal lobe (IPL) in manipulation judgement tasks. The objective here is to test these alternative predictions based on previous studies on manipulation judgment tasks using transcranial magnetic stimulations (TMS) targeting the left supramarginal gyrus (SMG). METHODS: We review recent TMS studies on manipulation judgement tasks and confront these data with predictions made by both tool use theories...
June 19, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28604704/thermoneutral-housing-exacerbates-nonalcoholic-fatty-liver-disease-in-mice-and-allows-for-sex-independent-disease-modeling
#18
Daniel A Giles, Maria E Moreno-Fernandez, Traci E Stankiewicz, Simon Graspeuntner, Monica Cappelletti, David Wu, Rajib Mukherjee, Calvin C Chan, Matthew J Lawson, Jared Klarquist, Annika Sünderhauf, Samir Softic, C Ronald Kahn, Kerstin Stemmer, Yoichiro Iwakura, Bruce J Aronow, Rebekah Karns, Kris A Steinbrecher, Christopher L Karp, Rachel Sheridan, Shiva K Shanmukhappa, Damien Reynaud, David B Haslam, Christian Sina, Jan Rupp, Simon P Hogan, Senad Divanovic
Nonalcoholic fatty liver disease (NAFLD), a common prelude to cirrhosis and hepatocellular carcinoma, is the most common chronic liver disease worldwide. Defining the molecular mechanisms underlying the pathogenesis of NAFLD has been hampered by a lack of animal models that closely recapitulate the severe end of the disease spectrum in humans, including bridging hepatic fibrosis. Here we demonstrate that a novel experimental model employing thermoneutral housing, as opposed to standard housing, resulted in lower stress-driven production of corticosterone, augmented mouse proinflammatory immune responses and markedly exacerbated high-fat diet (HFD)-induced NAFLD pathogenesis...
July 2017: Nature Medicine
https://www.readbyqxmd.com/read/28589361/the-aid-cre-ert2-model-a-tool-for-monitoring-b-cell-immune-responses-and-generating-selective-hybridomas
#19
Simon Le Gallou, Takuya Nojima, Daisuke Kitamura, Jean-Claude Weill, Claude-Agnès Reynaud
Expression of activation-induced cytidine deaminase (AID) is the hallmark of B cells engaged in an immune response in germinal centers. We designed an inducible fate-mapping reporter mouse in which AID-expressing B cells could be timely and irreversibly marked, by knockin at the Aicda locus of a tamoxifen-inducible Cre recombinase. This mouse model allows notably for the long-term follow-up of memory B cells and plasma cells engaged in an immune response. We describe here a protocol to generate hybridomas from small memory subsets that can be easily traced and identified in this mouse line through Cre-activated fluorescent reporters...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28580001/eggplant-resistance-to-the-ralstonia-solanacearum-species-complex-involves-both-broad-spectrum-and-strain-specific-quantitative-trait-loci
#20
Sylvia Salgon, Cyril Jourda, Christopher Sauvage, Marie-Christine Daunay, Bernard Reynaud, Emmanuel Wicker, Jacques Dintinger
Bacterial wilt (BW) is a major disease of solanaceous crops caused by the Ralstonia solanacearum species complex (RSSC). Strains are grouped into five phylotypes (I, IIA, IIB, III, and IV). Varietal resistance is the most sustainable strategy for managing BW. Nevertheless, breeding to improve cultivar resistance has been limited by the pathogen's extensive genetic diversity. Identifying the genetic bases of specific and non-specific resistance is a prerequisite to breed improvement. A major gene (ERs1) was previously mapped in eggplant (Solanum melongena L...
2017: Frontiers in Plant Science
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