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Infectious endophthalmitis

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https://www.readbyqxmd.com/read/29773945/predictive-factors-in-the-treatment-of-streptococcal-endophthalmitis
#1
Yosanan Yospaiboon, Kidakarn Meethongkam, Suthasinee Sinawat, Wipada Laovirojjanakul, Tanapat Ratanapakorn, Thuss Sanguansak, Chavakij Bhoomibunchoo
Objective: To evaluate visual outcomes and possible predictive factors in the treatment of infectious endophthalmitis caused by Streptococcus species during 2012-2016 at a large referral eye center in northeastern Thailand. Methods: A retrospective medical record chart review of patients with culture-positive endophthalmitis caused by Streptococcus species was conducted. Demographic data including age, gender, occupation, duration of symptoms, time to surgery, surgical procedures, initial visual acuity at presentation, and final visual acuity after treatment were collected and analyzed...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29746802/comparison-between-bactec-peds-plus-f-broth-and-conventional-medium-for-vitreous-culture
#2
Seyed Ali Tabatabaei, Seyed Mehdi Tabatabaei, Mohammad Soleimani, Bahman Hejrati, Ahmad Mirshahi, Alireza Khadabandeh, Aliasghar Ahmadraji, Niloofar Valipour
PURPOSE: To evaluate the yield of Bactec Peds Plus F broth for vitreous sample culture in cases with infectious endophthalmitis in comparison to conventional medium. PATIENTS AND METHODS: Consecutive cases of clinically suspected endophthalmitis were prospectively enrolled in this study. Cultures of the vitreous sample were performed in both Bactec Peds Plus F broth and conventional mediums. RESULTS: Forty eyes of 40 patients who were clinically suspected of infectious endophthalmitis with different etiologies were enrolled in this study...
May 10, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29740727/the-first-case-of-bacillus-calmette-gu%C3%A3-rin-induced-small-vessel-central-nervous-system-vasculitis
#3
REVIEW
Marc-Etienne Parent, Maxime Richer, Patrick Liang
To present an unrecognized vascular complication of bacillus Calmette-Guérin (BCG) therapy administered for superficial bladder carcinoma. We also review the potential mimickers for primary angiitis of the central nervous system (PACNS) as well as complications of intravesical BCG therapy. An 89-year-old Caucasian man with a history of relapsing high-grade bladder carcinoma treated with intravesical BCG presented with recurring episodes of right upper limb paresthesia with clumsiness and dysarthria. Magnetic resonance imaging of the head revealed multiple predominantly left-sided frontotemporal micronodular peri-vascular lesions...
May 9, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29740209/factors-affecting-visual-outcomes-after-treatment-of-infectious-endophthalmitis-in-northeastern-thailand
#4
Yosanan Yospaiboon, Anocha Intarapanich, Wipada Laovirojjanakul, Tanapat Ratanapakorn, Suthasinee Sinawat, Thuss Sanguansak, Chavakij Bhoomibunchoo
Objective: To determine factors affecting visual outcomes after treatment of infectious endophthalmitis during 2012-2016 at a large referral eye center in northeastern Thailand. Patients and methods: Medical charts of patients with a diagnosis of infectious endophthalmitis including demographic data, types of endophthalmitis, causative organisms, methods of treatment, anatomical, and functional outcomes were retrospectively reviewed. Factors associated with improved visual outcomes were analyzed...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29652690/endophthalmitis-after-pars-plana-vitrectomy-efficacy-of-intraoperative-subconjunctival-antibiotics
#5
Stephanie J Weiss, Murtaza K Adam, Xinxiao Gao, Anthony Obeid, Arunan Sivalingam, Mitchell S Fineman, Joseph I Maguire, Sunir J Garg, Julia Haller, David H Fischer, Jason Hsu
PURPOSE: To examine rates of acute infectious endophthalmitis after pars plana vitrectomy (PPV) in eyes that received intraoperative subconjunctival antibiotics versus eyes that did not. METHODS: A retrospective, nonrandomized, comparative case series of 18,886 consecutive cases of transconjunctival 23-, 25-, and 27-gauge PPV over a 5-year period was performed. The impact of prophylactic intraoperative subconjunctival antibiotics on the development of acute infectious postoperative endophthalmitis was examined...
April 12, 2018: Retina
https://www.readbyqxmd.com/read/29564359/femtosecond-laser-assisted-astigmatic-keratotomy-a-review
#6
REVIEW
John S M Chang
Background: Astigmatic keratotomy (AK) remains an accessible means to correct surgically induced or naturally occurring astigmatism. The advantages of femtosecond laser-assisted astigmatic keratotomy (FSAK) over conventional methods have been recognized recently. Main text: This review evaluates the efficacy, complications, and different methods of FSAK for correction of astigmatism in native eyes and those that underwent previous penetrating keratoplasty (PKP)...
2018: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/29543556/seasonal-hyperacute-panuveitis-in-nepal-a-review-over-40-years-of-surveillance
#7
Madan Upadhyay, Ranju Kharel Sitaula, Bharat Shrestha, Bhaiya Khanal, Bishnu Psd Upadhyay, Jeevan B Sherchand, Prakash Ghimire
PURPOSE: This review aims to provide a detailed update in Seasonal hypercute panuveitis (SHAPU) which is a blinding disease of unknown etiology reported only from Nepal, occurring every odd year since 1975 predominantly in children. METHODS: Data sources were literature reviewed using PubMed, Medline, and ISI Databases (since 1975 to late 2017). Search items included SHAPU, seasonal endophthalmitis, hypopyon uveitis, caterpillar induced uveitis alone or in combination with white moth, panuveitis, and review...
March 15, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29515160/genomics-based-identification-of-microorganisms-in-human-ocular-body-fluid
#8
Philipp Kirstahler, Søren Solborg Bjerrum, Alice Friis-Møller, Morten la Cour, Frank M Aarestrup, Henrik Westh, Sünje Johanna Pamp
Advances in genomics have the potential to revolutionize clinical diagnostics. Here, we examine the microbiome of vitreous (intraocular body fluid) from patients who developed endophthalmitis following cataract surgery or intravitreal injection. Endophthalmitis is an inflammation of the intraocular cavity and can lead to a permanent loss of vision. As controls, we included vitreous from endophthalmitis-negative patients, balanced salt solution used during vitrectomy and DNA extraction blanks. We compared two DNA isolation procedures and found that an ultraclean production of reagents appeared to reduce background DNA in these low microbial biomass samples...
March 7, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29503960/a-case-of-fungal-keratitis-and-endophthalmitis-post-penetrating-keratoplasty-resulting-from-fungal-contamination-of-the-donor-cornea
#9
Koji Kitazawa, Koichi Wakimasu, Kazuhito Yoneda, Bernie Iliakis, Chie Sotozono, Shigeru Kinoshita
Purpose: Fungal infections post keratoplasty due to contamination of the donor corneal graft have become important issues that need to be addressed. Here we report a case of fungal keratitis and endophthalmitis post penetrating keratoplasty (PKP) due to fungal contamination of the donor corneal graft. Observations: We present a 52-year-old male who underwent PKP with a donor corneal graft that was later found to be contaminated with fungus. At 4-weeks postoperative, infectious infiltrates suddenly appeared at the border between the host and donor corneal graft, and endophthalmitis concomitantly occurred...
April 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29503939/anterior-infectious-necrotizing-scleritis-secondary-to-pseudomonas-aeruginosa-infection-following-intravitreal-ranibizumab-injection
#10
Razek Georges Coussa, Susan M Wakil, Hady Saheb, David E Lederer, Karin M Oliver, Devinder P Cheema
Purpose: To report the occurrence and management of severe infectious scleritis in a 75 year-old woman following intravitreal ranibizumab injection. Observations: A 75 year-old monocular woman receiving monthly intravitreal ranibizumab injection for wet age related macular degeneration in the left eye presented with severe dull pain, decreased vision, and scleral melt with discharge 2 weeks after her last injection. The dilated fundus exam was devoid of vitritis...
April 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29487034/isolates-and-antibiotic-susceptibilities-of-endogenous-bacterial-endophthalmitis-a-retrospective-multicenter-study-in-japan
#11
Daisuke Todokoro, Kiyofumi Mochizuki, Takashi Nishida, Hiroshi Eguchi, Tatsuro Miyamoto, Takaaki Hattori, Takashi Suzuki, Tomoyuki Inoue, Ryohei Nejima, Saichi Hoshi, Hideo Akiyama
Endogenous bacterial endophthalmitis, also called metastatic endophthalmitis, is a rare bacterial endophthalmitis derived from distant infectious foci via the bloodstream. This infection can potentially cause not only severe visual disturbance, but also loss of the eyeball or death, as most patients are immunocompromised. This retrospective Japanese multicenter study analyzed 32 eyes in 25 definitive cases. Twelve patients (48.0%) had diabetes mellitus. Typical ocular findings were vitreous haze (87.5%), cells in the anterior chambers (62...
June 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29470930/diagnostic-utility-of-quantitative-polymerase-chain-reaction-versus-culture-in-endophthalmitis-and-uveitis
#12
Harpal Singh Sandhu, Amir Hajrasouliha, Henry J Kaplan, Wei Wang
PURPOSE: To compare genetic testing for microbes in infectious endophthalmitis or uveitis to culture. METHODS: This was a retrospective, single-center case series that enrolled patients with clinically suspected endophthalmitis or uveitis of unknown etiology. Aqueous humor or vitreous was collected and sent for routine cultures and genetic testing. RESULTS: In total, 46 patients were enrolled. Genetic testing was positive in 32/46 (70%) cases and culture 6/46 cases (13%)...
February 22, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29456673/full-thickness-conjunctival-flap-covering-surgery-combined-with-amniotic-membrane-transplantation-for-severe-fungal-keratitis
#13
Jing Zhong, Bowen Wang, Saiqun Li, Yuqing Deng, Haixiang Huang, Ling Chen, Jin Yuan
Fungal keratitis is a severe and common ocular infectious disease. The present study evaluated the efficiency of full-thickness conjunctival flap covering surgery with amniotic membrane transplantation (FCCS + AMT) as a transitional surgery for severe fungal keratitis. A total of 17 patients with severe fungal keratitis without corneal perforation underwent FCCS + AMT between January 2010 and December 2015. The pathogenic factors, preoperative diagnosis and postoperative prognosis of FCCS + AMT at 3 months were evaluated...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29454335/earliella-scabrosa-associated-postoperative-endophthalmitis-after-phacoemulsification-with-intraocular-lens-implantation-a-case-report
#14
Hong He, Xiaolian Chen, Hongshan Liu, Jiaochan Wu, Xingwu Zhong
BACKGROUND: Postoperative endophthalmitis after cataract surgery is a severe eye infection that can lead to irreversible blindness in the affected eye. The characteristics, treatment and prognosis of this disease vary because of its association with different pathogens. Here, we report what is possibly the first case of endophthalmitis after cataract surgery to be associated with the rare pathogen Earliella scabrosa. CASE PRESENTATION: A 56-year-old man from Hainan Island (China) with a history of phacoemulsification and type II diabetes mellitus underwent intraocular lens (IOL) implantation...
February 17, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29300514/surgical-preferences-in-the-management-of-recalcitrant-endophthalmitis
#15
Roxana Fu, Joseph Childs, William Nunery, Peter Timoney
To assess the practice patterns of current members of the American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) in the treatment of medically refractive endophthalmitis (MRE). A 17-question survey included the procedure of choice for MRE, the preferred type of orbital implant, the timing of implant placement, and the incidence of postoperative complications. 107 ASOPRS members participated in the study. In the setting of MRE, 72% preferred evisceration versus 28% who preferred enucleation...
January 4, 2018: Orbit
https://www.readbyqxmd.com/read/29260050/severe-corneal-ulcer-with-progression-to-endophthalmitis-and-high-grade-bacteremia
#16
Tomasz P Stryjewski, James Chodosh, Ivana K Kim, Miriam Baron Barshak, John B Miller
Purpose: Bacterial sepsis is a common consequence of many infectious processes. Here, we describe a case of a woman with a corneal ulcer who went on to develop group B streptococcal (GBS) endophthalmitis, bacteremia, and eventual loss of the eye. Observations: A previously healthy, immunocompetent, middle aged, contact lens wearing female who, after freshwater boating in her contact lenses, developed a red, painful eye. She was initially prescribed an hourly topical steroid by an outside optometrist but worsening of her condition prompted her to present to our Emergency Department...
June 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29223228/endophthalmitis-after-cataract-surgery-effect-of-behind-the-lens-washout
#17
Tetsuro Oshika, Yuichi Ohashi
PURPOSE: To analyze the outcomes of cataract surgery with emphasis on the relationship between surgery-related factors and the incidence of postoperative infectious endophthalmitis. SETTING: Ninety-three surgical sites in Japan. DESIGN: Prospective case series. METHODS: Eyes that were scheduled to have cataract surgery from January 20 to September 30, 2014, were included. Phacoemulsification and implantation of a single-piece hydrophobic acrylic foldable intraocular lens (IOL) were performed...
November 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29197165/the-treatment-of-postoperative-endophthalmitis-should-we-still-follow-the-endophthalmitis-vitrectomy-study-more-than-two-decades-after-its-publication
#18
Andrzej Grzybowski, Magdalena Turczynowska, Ferenc Kuhn
Conducted in the early 1990s Endophthalmitis Vitrectomy Study (EVS) have helped in establishing reasonable guidelines for the management of infectious postoperative endophthalmitis. However at present, more than 20 years after its publication, tremendous progress has been introduced in vitrectomy technology, which now permits the vitreoretinal surgeon to perform surgery more safely, and with better outcomes. Moerover, performing a complete vitreous removal, along with the moving up of the surgical intervention to as early as possible allows the prevention of complications that would limit the functional improvement postoperatively...
December 2, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29121361/valved-25-gauge-cannula-for-vitreous-tap-and-injection
#19
Theodore Leng, Darius M Moshfeghi
BACKGROUND AND OBJECTIVES: To describe a technique that reduces patient discomfort by using a valved 25-gauge trocar for vitreous tap and intravitreal injection of medications in previously vitrectomized eyes with suspected infectious endophthalmitis. PATIENTS AND METHODS: A commercially available 25-gauge valved entry system is used to enter the vitreous cavity. A 25-gauge needle attached to a syringe is used to obtain a vitreous specimen for microbiological access and administer intravitreal injections of antibiotics and steroids...
November 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29094328/incidence-of-endophthalmitis-and-the-perioperative-practices-of-cataract-surgery-in-japan-japanese-prospective-multicenter-study-for-postoperative-endophthalmitis-after-cataract-surgery
#20
MULTICENTER STUDY
Tomoyuki Inoue, Toshihiko Uno, Norio Usui, Shinichiro Kobayakawa, Kiyoshi Ichihara, Yuichi Ohashi
PURPOSE: To prospectively survey the incidence of endophthalmitis following cataract surgery and investigate the current perioperative practices in Japan. METHODS: Patients who underwent cataract surgery from January 2012 to December 2013 were included. Information on perioperative practices were recorded prospectively. Clinical characteristics were examined in cases with endophthalmitis. RESULTS: A total of 63,244 patients who underwent cataract surgery in 205 facilities were enrolled...
January 2018: Japanese Journal of Ophthalmology
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