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Infectious endophthalmitis

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https://www.readbyqxmd.com/read/27958225/pediatric-infectious-endophthalmitis-a-271-case-retrospective-study-at-a-single-center-in-china
#1
Meng Zhang, Ge-Zhi Xu, Rui Jiang, Ying-Qin Ni, Ke-Yan Wang, Rui-Ping Gu, Xin-Yi Ding
BACKGROUND: Pediatric infectious endophthalmitis is a serious sight-threatening disease for children. The purpose of this study was to investigate the etiology, microbiological spectrum, and visual outcomes of infectious endophthalmitis in children at a single institution in China. METHODS: It is a retrospective study of the medical records of all patients under 14 years of age with histories of infectious endophthalmitis, treated at a single institution from January 1, 2009 to January 1, 2015...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27941382/russian-keratoprosthesis-in-stevens-johnson-syndrome
#2
Xiao Ma, Ran Xiang, Xiaoli Meng, Limin Qin, Ying Wu, Lei Tain, Yanming Jiang, Yifei Huang, Liqing Wang
PURPOSE: To evaluate the efficacy and safety of Moscow Eye Microsurgery Complex in Russia (MICOF) keratoprosthesis (KPro) implantation in patients with Stevens-Johnson syndrome (SJS). METHODS: This was a retrospective case series. Fourteen eyes of 13 patients with SJS underwent KPro implantation at the Chinese People's Liberation Army General Hospital between April 1, 2000, and December 24, 2014. The visual outcome, KPro retention rate, and incidence of postoperative complications and their management were recorded and investigated...
December 8, 2016: Cornea
https://www.readbyqxmd.com/read/27939578/disseminated-aspergillosis-in-an-immunocompetent-patient-with-detectable-bis-methylthio-gliotoxin-and-negative-galactomannan
#3
Matxalen Vidal-García, Pilar Sáncehez-Chueca, María Pilar Domingo, Carlos Ballester, Lourdes Roc, Isabel Ferrer, María José Revillo, Julián Pardo, Eva María Gálvez, Antonio Rezusta
BACKGROUND: Disseminated invasive aspergillosis is an exceptional finding in immunocompetent hosts. As in immunocompromised patients, it has high mortality rates. Early diagnostic methods are required in order to properly manage the patient. Bis(methylthio)gliotoxin (bmGT) is a novel biomarker, useful in onco-hematological patients. CASE REPORT: A 70-year-old male, with non-insulin dependent type II diabetes mellitus and a past surgery history of aortic valve replacement with coronary by-pass five years ago, was seen in the emergency department with blurred vision...
December 8, 2016: Revista Iberoamericana de Micología
https://www.readbyqxmd.com/read/27896783/post-clear-corneal-phacoemulsification-endophthalmitis-profile-and-management-outcomes-at-a-tertiary-eye-care-center-in-western-india
#4
Aditya S Kelkar, Jai A Kelkar, Prajakta M Barve, Aishwarya Mulay, Shubhangi Sharma, Winfried Amoaku
BACKGROUND: Infectious endophthalmitis is a serious sight threatening intraocular inflammation that results from exogenous or endogenous spread of organisms into the eye.A retrospective case series to study the profile of endophthalmitis following clear corneal phacoemulsification in western India between years 2008 and 2014 was held in the National Institute of Ophthalmology, Pune, India. Cases of endophthalmitis post-clear corneal phacoemulsification were reviewed pertaining to demography, clinical history, surgeon experience, surgical complications, time of onset following surgery, duration between onset of symptoms and presentation to the center, presenting visual acuity and at follow-ups, slit-lamp examination and ultrasound findings, vitreous tap culture results, treatment, and final functional and anatomical outcomes...
December 2016: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/27887598/comparison-of-the-most-common-isolates-of-postoperative-endophthalmitis-in-south-korea-enterococcus-species-vs-coagulase-negative-staphylococci
#5
Ki Yup Nam, Hyun Wong Kim, Woo Jin Jeung, Jung Min Park, Jong Moon Park, In Young Chung, Yong Seop Han, Bu Sup Oum, Ji Eun Lee, Ik Soo Byon, Il Han Yun, Joo Eun Lee, Hee Sung Yoon, Dong Park, Byeng Chul Yu, Sang Joon Lee
BACKGROUND: To compare the related factors or manifestations of the two most common isolates of post-operative endophthalmitis, which were Enterococcus spp. and coagulase-negative staphylococci (CNS) in South Korea. METHODS: Medical records were reviewed for cases of post-operative endophthalmitis caused by Enterococcus spp. and CNS at eight institutions between January 2004 and July 2010. Various factors including age, sex, residence, systemic diseases, smoking and drinking history, and best corrected visual acuity, and length of time between causative intraocular surgery and symptom development were compared between the two groups...
November 25, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27849402/a-review-of-the-role-of-intravitreal-corticosteroids-as-an-adjuvant-to-antibiotics-in-infectious-endophthalmitis
#6
Dawn Ching Wen Ho, Aniruddha Agarwal, Cecilia S Lee, Jay Chhablani, Vishali Gupta, Manoj Khatri, Jayabalan Nirmal, Carlos Pavesio, Rupesh Agrawal
Infectious endophthalmitis is an important cause of vision loss worldwide. This entity most often occurs as a complication of intraocular surgery especially following cataract surgery or intravitreal injection. Endophthalmitis is regarded as a serious complication following ocular surgery and the final visual outcome is fundamentally contingent on timely recognition and intervention. Intravitreal and oral antibiotics in combination with pars plana vitrectomy or vitreous aspiration remain the mainstay in the management of endophthalmitis...
November 16, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27832911/endophthalmitis-after-intravitreal-injections-incidence-management-and-prognosis
#7
R Tarragó, J L Olea, C Ramírez, L Escudero
OBJECTIVE: To assess the rate of endophthalmitis after intravitreal injection (IVI) in a «clean room» of a single health centre, following the guidelines of the Spanish Vitreo-Retinal Society (SERV). An analysis was performed on the culture specimens, response to treatment, and final outcomes (guidelines). MATERIAL AND METHODS: A retrospective, observational study was conducted on a consecutive case series of patients diagnosed with infectious endophthalmitis after IVI in a single health centre between 2010 and 2015...
November 7, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27793818/randomised-controlled-trial-of-prophylactic-antibiotic-treatment-for-the-prevention-of-endophthalmitis-after-open-globe-injury-at-groote-schuur-hospital
#8
N Du Toit, S Mustak, C Cook
BACKGROUND/AIMS: Most post-traumatic acute infectious endophthalmitis occur within a week of open globe trauma, necessitating early antibiotic prophylaxis. There are few randomised studies that demonstrate the benefits of prophylactic antibiotics. This randomised controlled non-inferiority trial was aimed at determining the incidence of post-traumatic endophthalmitis using established intravenous/oral prophylaxis and comparing this to the incidence using oral antibiotics only. METHODS: All adult patients admitted with open globe injury were included...
October 28, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27792412/the-role-of-vitrectomy-in-the-management-of-fungal-endophthalmitis
#9
Yewlin E Chee, Dean Eliott
Fungal endophthalmitis is an important cause of vision loss worldwide with a large body of literature describing the treatment of the disease. The evidence supporting the use of pars plana vitrectomy in the management of fungal endophthalmitis is largely comprised of case reports and case series and demonstrates the important role of vitrectomy surgery. Vitrectomy can improve the likelihood of establishing the diagnosis, enhance the treatment of infection by removing fungal elements in the vitreous, aid in the removal of other inoculated intraocular structures, and is an important tool in the management of vision-threatening post-infectious sequelae like retinal detachment and epiretinal membrane...
2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27779558/microbiologic-spectrum-and-visual-outcomes-of-acute-onset-endophthalmitis-undergoing-therapeutic-pars-plana-vitrectomy
#10
Jayanth Sridhar, Yoshihiro Yonekawa, Ajay E Kuriyan, Anthony Joseph, Benjamin J Thomas, Michelle C Liang, Nadim Rayess, Nidhi Relhan, Jeremy D Wolfe, Chirag P Shah, Andre J Witkin, Harry W Flynn, Sunir J Garg
PURPOSE: To report the clinical presentation, microbiologic spectrum, and visual outcomes associated with acute-onset infectious endophthalmitis undergoing therapeutic pars plana vitrectomy. METHODS: Multicenter interventional retrospective noncomparative consecutive case series. Billing records were reviewed to identify all charts for patients undergoing pars plana vitrectomy within 14 days of diagnosis of acute-onset infectious endophthalmitis over a 4-year period at 5 large tertiary referral retina practices...
October 21, 2016: Retina
https://www.readbyqxmd.com/read/27766175/possible-relation-between-lack-of-posterior-vitreous-detachment-and-severe-endogenous-endophthalmitis
#11
Kazuhiko Umazume, Jun Suzuki, Yoshihiko Usui, Yoshihiro Wakabayashi, Hiroshi Goto
Purpose. Endogenous endophthalmitis (EE) is a rare ocular disease caused by bacterial or fungal infection of intraocular spaces by hematogenous spread of pathogens from distant infectious loci in the body. We investigated the clinical characteristics and management of eyes with EE in ten consecutive patients. Methods. Ten patients (10 eyes) with EE treated at Tokyo Medical University Hospital in 2014 were reviewed. We retrospectively studied the causative organisms, systemic complications, pre/postoperative mean best-corrected visual acuity (BCVA), and status of posterior vitreous detachment (PVD)...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27726522/the-spectrum-of-uveitis-in-southern-vietnam
#12
Myhanh Nguyen, Jay Siak, Soon-Phaik Chee, Vo Quang Hong Diem
PURPOSE: To describe the pattern of uveitis among Vietnamese at two eye hospitals in Southern Vietnam. METHODS: We retrospectively reviewed the charts of 212 consecutive uveitis cases that presented to two eye hospitals in Ho Chi Minh City, Vietnam, from July 2011 to February 2015. The patients were identified from a database maintained by the hospitals. Patients with keratitis, episcleritis, orbital inflammation, post-surgical endophthalmitis, traumatic iritis, and corneal graft rejection were excluded...
October 11, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27673715/infectious-endophthalmitis-after-glaucoma-drainage-implant-surgery-clinical-features-microbial-spectrum-and-outcomes
#13
Cindy X Zheng, Marlene R Moster, M Ali Khan, Allen Chiang, Sunir J Garg, Yang Dai, Michael Waisbourd
PURPOSE: To report the clinical features, microbial spectrum, and treatment outcomes of endophthalmitis after glaucoma drainage implant (GDI) surgery. METHODS: Records of patients diagnosed with endophthalmitis after GDI surgery were reviewed. Data on clinical course, microbiological laboratory results, and treatment were analyzed. RESULTS: Of 1,891 eyes that underwent GDI surgery, 14 eyes (0.7%) developed endophthalmitis. The mean time interval between GDI surgery and diagnosis of endophthalmitis was 2...
September 26, 2016: Retina
https://www.readbyqxmd.com/read/27646336/intravitreal-dexamethasone-in-the-management-of-acute-endophthalmitis-a-comparative-retrospective-study
#14
Elad Moisseiev, Sam Abbassi, Susanna S Park
PURPOSE: To compare the clinical outcome of eyes with acute bacterial endophthalmitis treated with intravitreal injection of antibiotics with or without intravitreal dexamethasone. METHODS: This was a retrospective chart review of 63 eyes diagnosed with acute bacterial endophthalmitis and treated with vitreous tap and intravitreal injection of antibiotics, 19 eyes (30.2%) with and 44 eyes (69.8%) without concurrent intravitreal dexamethasone. RESULTS: Visual acuity had significantly improved by 1 week and was maintained long-term (p<0...
September 13, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/27621301/recurrent-fungal-keratitis-and-blepharitis-caused-by-aspergillus-flavus
#15
Chia-Yi Lee, Yi-Ju Ho, Chi-Chin Sun, Hsin-Chiung Lin, Ching-Hsi Hsiao, David Hui-Kang Ma, Chi-Chun Lai, Hung-Chi Chen
Aspergillus species produces a wide spectrum of fungal diseases like endophthalmitis and fungal keratitis ophthalmologically, but there has been no report about blepharitis caused by Aspergilus flavus to date. Herein, we report a 61-year-old ethnic Han Taiwanese male who had suffered from pain with burning and foreign body sensation after an insect bite on his left eye. Specimens from bilateral eyelids suggested infection of A. flavus, whereas corneal scraping showed the presence of Gram-negative bacteria. He was admitted for treatment of infectious keratitis with topical antibiotic and antifungal eye drops...
November 2, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27614591/safety-of-concurrent-boston-type-i-keratoprosthesis-and-glaucoma-drainage-device-implantation
#16
Tamara L Lenis, Stephan Y Chiu, Simon K Law, Fei Yu, Anthony J Aldave
PURPOSE: To evaluate the safety of concurrent Boston type I keratoprosthesis (KPro) and glaucoma drainage device (GDD) implantation. DESIGN: Retrospective comparative study of a consecutive cohort of patients. SUBJECTS: Patients who underwent KPro implantation by a single surgeon (A.J.A.) with or without 1 concurrent Ahmed GDD (New World Medical, Inc., Rancho Cucamonga, CA) implantation between January 1, 2005, and January 31, 2015, were included...
January 2017: Ophthalmology
https://www.readbyqxmd.com/read/27614460/methicillin-resistance-and-biofilm-production-of-staphylococcus-epidermidis-isolates-from-infectious-and-normal-flora-conjunctiva
#17
Norma Fariña, Margarita Samudio, Letizia Carpinelli, Martin M Nentwich, Herminia Mino de Kaspar
PURPOSE: Coagulase-negative staphylococci have been reported to be the most frequent cause of bacterial postoperative endophthalmitis. Biofilm formation is the major virulence factor of Staphylococcus epidermidis and is often associated with methicillin resistance. This study aims at evaluating the presence of biofilm-producing and methicillin resistance genes (mecA) in S. epidermidis. METHODS: S. epidermidis isolated from clinically infected sites (group 1) and from normal human conjunctiva (group 2) were studied...
September 10, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27541384/clinical-patterns-of-uveitis-in-tertiary-ophthalmology-centers-in-seoul-south-korea
#18
Joo Yong Lee, Dong Yoon Kim, Se Joon Woo, Tae Wan Kim, Sang Jin Kim, Christopher Seungkyu Lee, Kyu Seop Kim, Kyung Hoon Seo, Hyung Woo Kwak
PURPOSE: To identify the characteristics and causes of uveitis in Seoul, South Korea. METHODS: We performed a retrospective medical record review of 602 patients diagnosed with uveitis at seven tertiary ophthalmology centers between January and December 2013. RESULTS: The most common type of uveitis was anterior uveitis (n = 281), followed by posterior uveitis (n = 152), panuveitis (n = 126), and intermediate uveitis (n = 43). Among patients with an identified cause (n = 252), 149 and 103 had non-infectious and infectious uveitis, respectively, and ankylosing spondylitis (n = 53), Behcet disease (n = 43), and endophthalmitis (n = 25) were common identified causes of uveitis...
August 19, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27538795/long-term-visual-outcomes-and-complications-of-boston-keratoprosthesis-type-ii-implantation
#19
Ramon Lee, Ziad Khoueir, Edem Tsikata, James Chodosh, Claes H Dohlman, Teresa C Chen
PURPOSE: To report the long-term visual outcomes and complications after Boston keratoprosthesis type II implantation in the largest single-center case series with the longest average follow-up. DESIGN: Retrospective review of consecutive clinical case series. PARTICIPANTS: Between January 1992 and April 2015 at the Massachusetts Eye and Ear Infirmary, 48 eyes of 44 patients had keratoprosthesis type II implanted by 2 surgeons (C.H.D. and J...
January 2017: Ophthalmology
https://www.readbyqxmd.com/read/27465568/pars-plana-vitrectomy-for-late-vitreoretinal-sequelae-of-infectious-endophthalmitis-surgical-management-and-outcomes
#20
Benjamin J Thomas, Neesurg Mehta, Yoshihiro Yonekawa, Jayanth Sridhar, Ajay E Kuriyan, Nidhi Rehlan, Michelle C Liang, Maria A Woodward, Andre J Witkin, Chirag Shah, Harry W Flynn, Sunir J Garg, Jeremy D Wolfe
PURPOSE: To report the visual acuity outcomes after pars plana vitrectomy for delayed vitreoretinal sequelae of infectious endophthalmitis. All eyes were initially treated with intravitreal antibiotics (Abx). METHODS: Multicenter, retrospective, consecutive case series. RESULTS: Forty-two eyes met the study criteria. The mean follow-up was 48 weeks (SD ± 61.8). Mean interval from Abx to pars plana vitrectomy was 13 weeks (SD ± 14.3, range 2-70)...
July 26, 2016: Retina
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