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Enterococcus faecalis endophthalmitis

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https://www.readbyqxmd.com/read/28707018/postoperative-enterococcus-faecalis-endophthalmitis-virulence-factors-leading-to-poor-visual-outcome
#1
Daisuke Todokoro, Takashi Suzuki, Shinichiro Kobayakawa, Haruyoshi Tomita, Yuichi Ohashi, Hideo Akiyama
Purpose Postoperative endophthalmitis caused by Enterococcus faecalis often results in poor visual outcome due to retinal destruction. We evaluated the virulence factors of Enterococcus faecalis clinical isolates and analyzed their relationship with retinal destruction and poor visual outcomes in postoperative bacterial endophthalmitis (PBE) following cataract surgery. STUDY DESIGN: Retrospective. METHODS: E. faecalis isolates from nine acute-onset PBE cases were examined using pulsed-field gel electrophoresis of genomic DNA, plasmid isolation and pheromone response experiments...
July 13, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28619977/infectious-crystalline-keratopathy-after-descemet%C3%A3-%C3%A2-%C3%A2-s-stripping-endothelial-keratoplasty
#2
Ashley J Porter, Graham A Lee, Kevin Whitehead
A 68-year-old woman presented with infectious crystalline keratopathy 4 months after she underwent a combined phacoemulsification and Descemet's stripping endothelial keratoplasty for Fuch's endothelial dystrophy in her left eye. After 5 months of topical moxifloxacin 1%, the infiltrate responded well but had not completely resolved, with the resulting endothelial failure requiring a penetrating keratoplasty 9 months after the initial operation. Microbiology identified Enterococcus faecalis with the histopathology demonstrating bacterial colonies within the graft interface...
June 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28365853/vitreous-hemorrhage-as-an-early-sign-of-acute-bacterial-endophthalmitis-following-intravitreal-ranibizumab-injection
#3
Yishay Weill, Koby Brosh, Tamar Levi-Vineberg, Joel Hanhart
PURPOSE: To report a case of acute bacterial endophthalmitis after antivascular endothelial growth factor injection with a rare presentation of vitreous hemorrhage. METHODS: An 84-year-old woman presented with sudden painless vision loss in her left eye, 3 days after intravitreal ranibizumab injection for cystoid macular edema due to neovascular age-related macular degeneration. The patient was otherwise asymptomatic. Dense vitreous hemorrhage was observed. At follow-up the next day, the patient complained on severe left eye pain...
April 1, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28222703/comparison-of-methods-for-identifying-causative-bacterial-microorganisms-in-presumed-acute-endophthalmitis-conventional-culture-blood-culture-and-pcr
#4
COMPARATIVE STUDY
Pear Pongsachareonnont, Worawalun Honglertnapakul, Tanittha Chatsuwan
BACKGROUND: Identification of bacterial pathogens in endophthalmitis is important to inform antibiotic selection and treatment decisions. Hemoculture bottles and polymerase chain reaction (PCR) analysis have been proposed to offer good detection sensitivity. This study compared the sensitivity and accuracy of a blood culture system, a PCR approach, and conventional culture methods for identification of causative bacteria in cases of acute endophthalmitis. METHODS: Twenty-nine patients with a diagnosis of presumed acute bacterial endophthalmitis who underwent vitreous specimen collection at King Chulalongkorn Memorial Hospital were enrolled in this study...
February 21, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27906556/combination-effect-of-cefuroxime-and-levofloxacin-against-bacteria-isolated-from-the-healthy-conjunctival-sac-and-endophthalmitis-cases-using-a-fractional-inhibitory-concentration-index
#5
Takashi Suzuki, Toshihiro Yamamoto, Tomohiko Torikai, Yuichi Ohashi
PURPOSE: Intracameral cefuroxime (CXM) and antibiotic eye drops such as fluoroquinolone are widely used for preventing endophthalmitis after cataract surgery. However, few reports are available regarding their interactions. This study was conducted to examine the in vitro interaction of CXM and levofloxacin (LVFX) against bacterial isolates from the healthy conjunctival sac before cataract surgery and from endophthalmitis cases. METHODS: The activity of each drug was determined using a broth dilution method...
January 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27797843/endocarditis-and-monocular-blindness
#6
Jack Andrews, Shyamanga Borooah
A man aged 77 years with postrenal transplant lymphoproliferative disease was admitted with high fever, elevated inflammatory markers and a heart murmur. Blood cultures grew Enterococcus faecalis and he was found to have mitral valve endocarditis on echocardiogram and subsequently started on appropriate antibiotics. 5 days into treatment, he developed ocular symptoms and 3 days later, he had irreversible monocular visual loss. He was seen by the ophthalmology team who diagnosed endogenous endopthalmitis secondary to bacteraemic spread from his endocarditis...
October 26, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27422143/isolates-and-antibiotic-susceptibilities-of-endophthalmitis-in-postcataract-surgery-a-12-year-review-of-culture-proven-cases
#7
Yu Ti Teng, Mei Ching Teng, Hsi Kung Kuo, Po Chiung Fang, Pei Chang Wu, Chih Hsin Chen, Ming Tse Kuo, I Hui Yang, Yung Jen Chen
The purpose of this study was to investigate the spectrum of organisms causing endophthalmitis after cataract surgery in a tertiary medical center in Taiwan and the antibiotic susceptibilities. This was a retrospective case series study. Patients with endophthalmitis after cataract surgery from January 2004 to July 2015 were reviewed. The outcome measures included the identification of isolates, antibiotic susceptibilities, and final visual outcomes. Twenty-one organisms were isolated from 19 cases. The most common organisms were Enterococcus in 38...
July 15, 2016: International Ophthalmology
https://www.readbyqxmd.com/read/27419840/risk-factors-for-aerobic-bacterial-conjunctival-flora-in-preoperative-cataract-patients
#8
S Hoshi, M Hashida, K Urabe
PurposeTo investigate the relationship between the background of preoperative cataract patients and bacterial conjunctival flora.MethodsA total of 990 cataract patients who had completed preoperative examinations in 2007 and 2008 were included. Patients using topical antibiotics at the preoperative examination or having a history of intraocular surgery were excluded. Conjunctival cultures had been preoperatively obtained. Patient characteristics were investigated via medical records. Risk factors for conjunctival flora of seven typical bacteria were analyzed by univariate and multivariate analyses...
November 2016: Eye
https://www.readbyqxmd.com/read/26888274/-clinical-observations-of-acute-onset-endophthalmitis-after-clear-corneal-phacoemulsification
#9
Yusen Huang, Ying Zhan, Lixin Xie
OBJECTIVE: To evaluate the incidence of acute-onset endophthalmitis after clear corneal phacoemulsification and to report its clinical features, microbiology, and therapeutic efficacy. METHODS: It was a retrospective case series study. Medical records were reviewed for all patients diagnosed with acuteonset postoperative endophthalmitis from 2006 through 2013 associated with cataract surgery at Shandong Eye Institute of China. RESULTS: The 8-year frequency of acute-onset endophthalmitis after clear corneal phacoemulsification was 0...
December 2015: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/26346615/enterococcus-faecalis-endophthalmitis-as-a-metastatic-complication-of-hemodialysis-vascular-access-related-sepsis-a-case-report-and-review-of-the-literature
#10
REVIEW
Osman Zikrullah Sahin, Ekrem Kara, Tahir Belice, Teslime Ayaz, Serap Baydur Sahin, Cinar Ozturk, Safak Yildirim, Yavuz Metin, Tuncay Sahutoglu
Catheter and/or arteriovenous (A-V) graft-related bacteremia is an important cause of morbidity and mortality among hemodialysis (HD) patients. Endocarditis, septic arthritis, epidural abscess, septic embolism, and osteomyelitis are the most common complications of catheter and/or A-V graft-related bacteremia; however, endogenous endophthalmitis is rarely seen. To the best of our knowledge, Enterococcus faecalis is the first case report in this population. We hereby report a case of endogenous endophthalmitis caused by E...
July 2016: Hemodialysis International
https://www.readbyqxmd.com/read/26125869/clinical-features-and-treatment-of-endophthalmitis-after-cataract-surgery
#11
J Zhu, Z H Li
The aim of this study was to investigate the clinical features and treatment results of endophthalmitis after cataract surgery. Five patients with endophthalmitis after phacoemulsification with intraocular lens implantation were enrolled in this study. The pathogenesis, clinical manifestation, and surgical outcomes of 5 patients were compared. Three patients were surgically treated with anterior chamber irrigation and vitrectomy with intravitreal injection. The remaining two patients were medically treated with an intravitreal injection of vancomycin and ceftazidime...
2015: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/25764616/bacteriological-findings-and-antimicrobial-susceptibility-pattern-of-isolated-pathogens-from-visual-threatening-ocular-infections
#12
Usanee Reinprayoon, Supapan Sitthanon, Ngamjit Kasetsuwan, Anan Chongthaleong
OBJECTIVE: To study the profiles and antimicrobial susceptibility pattern of isolated bacteria from visual threatening ocular infection. MATERIAL AND METHOD: This is a retrospective review of all microbiological culture reports from visual threatening ocular infection patients admitted at King Chulalongkorn Memorial Hospital from 2005 to 2009. The culture reports with antimicrobial susceptibility pattern were analyzed and correlated with clinical presentation. RESULTS: There were 682 specimens from 282 patients (286 eyes)...
January 2015: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/25658242/daptomycin-versus-vancomycin-in-an-enterococcus-faecalis-endophthalmitis-rabbit-model
#13
COMPARATIVE STUDY
Muammer Ozcimen, Muhammet G Kurtoglu, Sertan Goktas, Ethem Omeroglu, Yasar Sakarya, Ismail Alpfidan, Serap Ozcımen, Rabia Sakarya, Halil I Yener, Lutfi S Demir, Faik Saglam
PURPOSE: To compare bactericidal activities of daptomycin (DAP) and vancomycin (VAN) in an experimental rabbit model of Enterococcus faecalis endophthalmitis. MATERIALS AND METHODS: The right vitreous cavities of 24 New Zealand rabbits were inoculated with 100 colony-forming units of E. faecalis; and after 24 h, rabbits were randomly divided into three groups. DAP group (n = 8, 0.2 mg/0.05 ml intravitreally), VAN group (n = 8, 1 mg/0.05 ml intravitreally) and balanced salt solution group (BSS, n = 8, 0...
2016: Current Eye Research
https://www.readbyqxmd.com/read/25089354/endophthalmitis-caused-by-enterococcus-faecalis-clinical-features-antibiotic-sensitivities-and-outcomes
#14
Ajay E Kuriyan, Jayanth Sridhar, Harry W Flynn, William E Smiddy, Thomas A Albini, Audina M Berrocal, Richard K Forster, Peter J Belin, Darlene Miller
PURPOSE: To report the clinical features, antibiotic sensitivities, and visual acuity outcomes of endophthalmitis caused by Enterococcus faecalis. STUDY DESIGN: Retrospective, observational case series. METHODS: A consecutive case series of patients with culture-positive endophthalmitis caused by E. faecalis between January 1, 2002, and December 31, 2012, at an academic referral center. RESULTS: Of 14 patients identified, clinical settings included bleb association (n = 8), occurrence after cataract surgery (n = 4), and occurrence after penetrating keratoplasty (n = 2)...
November 2014: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/24505932/-postcataract-endophthalmitis-caused-by-enterococcus-faecalis
#15
Takashi Suzuki, Daisuke Todokoro, Shinichiro Kobayakawa, Chie Sotozono, Shuichiro Eguchi, Kazunori Miyata, Hiroko Bissen Miyajima, Yasuyoshi Ike, Yuichi Ohashi
PURPOSE: Enterococcus faecalis is a major endophthalmitis-causing pathogen and often causes significant visual impairment. We investigated the clinical background, treatment and the visual outcome of patients with E. faecalis endophthalmitis after cataract surgery. METHODS: We retrospectively conducted a postal survey directed mainly at the members of Japanese Society of Cataract and Refractive Surgery, and collected data on 30 eyes of 30 patients with E. faecalis endophthalmitis...
January 2014: Nippon Ganka Gakkai Zasshi
https://www.readbyqxmd.com/read/24410272/ocular-penetration-and-efficacy-of-levofloxacin-using-different-drug-delivery-techniques-for-the-prevention-of-endophthalmitis-in-rabbit-eyes-with-posterior-capsule-rupture
#16
Takahiro Uda, Takashi Suzuki, Arisa Mitani, Yoshitaka Tasaka, Shiro Kawasaki, Tsuyoshi Mito, Yuichi Ohashi
PURPOSE: To evaluate the effects of different drug-delivery techniques for levofloxacin (LVFX) in ocular penetration and the prevention of endophthalmitis using an aphakic rabbit model with posterior capsule rupture (PCR). METHODS: LVFX was administered to aphakic rabbit eyes with or without PCR using eye drops (EDs), subconjunctival injection (SCI), or intracameral (IC) injection. The concentration of the drug in the vitreous and aqueous humors was estimated at 2 h after injection...
May 2014: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/24248809/friends-group-clinical-and-microbiological-characteristics-of-post-filtering-surgery-endophthalmitis
#17
E Brillat-Zaratzian, A Bron, F Aptel, J P Romanet, P L Cornut, F Vandenesch, S Boisset, M Maurin, C Chiquet
PURPOSE: To study the clinical and microbiological characteristics as well as the prognostic factors for post-filtering surgery endophthalmitis. METHODS: Twenty-three eyes were included in the study in four tertiary centres between 2004 and 2010. The clinical and microbiological data were collected prospectively (minimum follow-up, 6 months). Microbiological diagnosis was based on conventional cultures and panbacterial PCR (16SrDNA amplification and sequencing)...
January 2014: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/24072645/emergence-of-enterococcus-species-in-the-infectious-microorganisms-cultured-from-patients-with-endophthalmitis-in-south-korea
#18
MULTICENTER STUDY
H W Kim, S Y Kim, I Y Chung, Joo Eun Lee, Ji Eun Lee, Jung Min Park, Jong Moon Park, Y S Han, B S Oum, I S Byon, I H Yun, H S Yoon, D Park, W J Jeong, B C Yu, I Park, T Bae, K Y Nam, S J Lee
PURPOSE: To investigate the microorganisms in culture-proven endophthalmitis and their susceptibilities to antimicrobial agents commonly used in South Korea. METHODS: Medical records of consecutive patients with culture-proven endophthalmitis at eight institutions between 1 January 2004 and 31 July 31 2010 were reviewed. Four categories of endophthalmitis were studied: postoperative, posttraumatic, endogenous, and unspecified. Outcome measures were culture-proven infectious organisms, antimicrobial susceptibilities, and final visual acuity in the patients...
February 2014: Infection
https://www.readbyqxmd.com/read/24028653/endogenous-endophthalmitis-caused-by%C3%A2-enterococcus-faecalis-in-a-cat
#19
E Donzel, E Reyes-Gomez, S Chahory
A three-year-old male neutered domestic shorthair cat was presented for loss of vision associated with hyperthermia, lethargy and anorexia. Ophthalmic examination revealed a bilateral panuveitis. Cytological examination of aqueous and vitreous humours was performed and revealed a suppurative inflammation associated with numerous cocci. Enterococcus faecalis was identified by bacterial culture from aqueous and vitreous humour. No primary infection site was identified. Active uveitis resolved after systemic antibiotic therapy, but the vision loss was permanent...
February 2014: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/23936701/enterococcus-faecalis-endogenous-endophthalmitis-from-valvular-endocarditis
#20
Sidnei Barge, Renata Rothwell, Rosário Varandas, Luís Agrelos
We report a case of a 74-year-old female, with a mitral heart valve, who presented with pain and blurred vision in the right eye for 2 days. Her visual acuity was light perception (LP) in the right eye and 20/40 in the left eye. Slit lamp examination showed corneal edema and hypopyon, and a view of the right fundus was impossible. Echography showed vitreous condensation. One day after presentation, the patient developed acute lung edema requiring hospitalization, so she was not submitted to vitreous tap and intravitreal treatment...
2013: Case Reports in Ophthalmological Medicine
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