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https://www.readbyqxmd.com/read/29153416/frequency-of-detection-of-chlamydophila-pneumoniae-using-bronchoalveolar-lavage-fluid-in-patients-with-community-onset-pneumonia
#1
Shingo Noguchi, Kazuhiro Yatera, Toshinori Kawanami, Kazumasa Fukuda, Kei Yamasaki, Keisuke Naito, Kentaro Akata, Hiroshi Ishimoto, Hiroshi Mukae
BACKGROUND: Chlamydophila pneumoniae is a causative pathogen of lower respiratory tract infection, which generally infects healthy, young people. However, it is often difficult to evaluate acute C. pneumoniae infection using upper respiratory tract specimens and/or sputum samples due to its persistent infection or colonization. The interpretation of frequency of detection of C. pneumoniae seems to be insufficient in community-onset pneumonia. The aim of this study was to evaluate the presence of C...
November 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/29021189/presence-of-atopy-increases-the-risk-of-asthma-relapse
#2
Laurel Teoh, Ian M Mackay, Peter P Van Asperen, Jason P Acworth, Mark Hurwitz, John W Upham, Weng Hou Siew, Claire Y T Wang, Theo P Sloots, Teresa Neeman, Anne B Chang
OBJECTIVES: To describe the point prevalence of respiratory viruses/atypical bacteria using PCR and evaluate the impact of respiratory viruses/atypical bacteria and atopy on acute severity and clinical recovery in children with hospitalised and non-hospitalised asthma exacerbations. DESIGN: This was a prospective study performed during 2009-2011. SETTING: The study was performed in the emergency departments of two hospitals. PATIENTS: 244 children aged 2-16 years presenting with acute asthma to the emergency departments were recruited...
October 11, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28922613/the-etiology-of-community-acquired-pneumonia-among-children-under-5%C3%A2-years-of-age-in-mainland-china-2001-2015-a-systematic-review
#3
Guijun Ning, Xuxia Wang, Dan Wu, Zundong Yin, Yixing Li, Huaqing Wang, Weizhong Yang
BACKGROUND: The aim of this systematic review was to examine the etiology of community-acquired pneumonia (CAP) among Chinese children younger than 5 y and provide evidence for further cost-effectiveness analyses for vaccine development, diagnostic strategies and empirical treatments. METHODS: The literature review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Data were obtained by searching PubMed, Embase, Web-of Science, and the Chinese databases Wanfang Data and China National Knowledge Infrastructure...
September 18, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28919691/molecular-etiopathology-of-naturally-occurring-reproductive-diseases-in-female-goats
#4
V Beena, R V S Pawaiya, K Gururaj, D D Singh, A K Mishra, N K Gangwar, V K Gupta, R Singh, A K Sharma, M Karikalan, Ashok Kumar
AIM: The aim of the present study was to investigate the molecular etiopathology of occurrence of reproductive diseases in female goats. Reproductive diseases in goats account for major economic losses to goat farmers in terms of valuable loss of offspring and animal productivity. MATERIALS AND METHODS: A total of 660 female genitalia were examined for pathological conditions (macroscopic and microscopic lesions). The etiopathological study was carried out for the presence of pathogenic organisms such as Brucella, Chlamydia, and Campylobacter in the uterus and ovary...
August 2017: Veterinary World
https://www.readbyqxmd.com/read/28913776/interactions-of-antisera-to-different-chlamydia-and-chlamydophila-species-with-the-ribosomal-protein-rps27a-correlate-with-impaired-protein-synthesis-in-a-human-choroid-plexus-papilloma-cell-line
#5
Abdullah Almamy, Christian Schwerk, Horst Schroten, Hiroshi Ishikawa, Abdul Rahman Asif, Bernhard Reuss
Chlamydia trachomatis (CT) and the Chlamydophila species (CS) Chlamydophila pneumoniae (CPn), and Chlamydophila psittaci (CPs) are suggested to induce autoantibodies causative of several human autoimmune disorders like rheumatoid arthritis and systemic lupus erythematosus (SLE). The aim of the present study was therefore to identify cellular protein interaction partners with antisera to CT (α-CT) or CS (α-CS) and to identify functional consequences of such interaction in vitro. As detected with a commercial first trimester human prenatal brain multiprotein array (hEXselect, Engine, Germany), the most frequent interaction partner with both α-CT and α-CS was the ribosomal small subunit protein RPS27a...
September 14, 2017: Immunologic Research
https://www.readbyqxmd.com/read/28891690/compendium-of-measures-to-control-chlamydia-psittaci-infection-among-humans-psittacosis-and-pet-birds-avian-chlamydiosis-2017
#6
Gary Balsamo, Angela M Maxted, Joanne W Midla, Julia M Murphy, Ron Wohrle, Thomas M Edling, Pilar H Fish, Keven Flammer, Denise Hyde, Preeta K Kutty, Miwako Kobayashi, Bettina Helm, Brit Oiulfstad, Branson W Ritchie, Mary Grace Stobierski, Karen Ehnert, Thomas N Tully
Psittacosis, also known as parrot fever and ornithosis, is a bacterial infection that can cause severe pneumonia and other serious health problems in humans. It is caused by Chlamydia psittaci. Reclassification of the order Chlamydiales in 1999 into 2 genera (Chlamydia and Chlamydophila) was not wholly accepted or adopted. This resulted in a reversion to the single, original genus Chlamydia, which now encompasses all 9 species including Chlamydia psittaci. During 2003-2014, 112 human cases of psittacosis were reported to the Centers for Disease Control and Prevention through the Nationally Notifiable Diseases Surveillance System...
September 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28886324/atypical-bacterial-etiology-of-acute-respiratory-infections-and-clinical-characterizations-among-iranian-children
#7
M Halaji, T Hashempour, G R Pouladfar, F Ghasabi, R Khashei
Acute respiratory infections (ARIs) in children younger than 5 years of age are one of the leading causes of morbidity and mortality, particularly in developing countries. Mycoplasma pneumoniae and Chlamydophila pneumoniae are prevalent causative agents of ARIs, worldwide. We sought M. pneumoniae and C. pneumoniae in respiratory samples from Iranian children with ARIs.  From November 2014 to April 2015, respiratory samples of 150 children aged 1 month to 15 years old were screened for presence of M. pneumoniae and C...
August 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28856082/atypical-bacterial-pneumonia-in-the-hiv-infected-population
#8
REVIEW
Breanne M Head, Adriana Trajtman, Zulma V Rueda, Lázaro Vélez, Yoav Keynan
Human immunodeficiency virus (HIV)-infected individuals are more susceptible to respiratory tract infections by other infectious agents (viruses, bacteria, parasites, and fungi) as their disease progresses to acquired immunodeficiency syndrome. Despite effective antiretroviral therapy, bacterial pneumonia (the most frequently occurring HIV-associated pulmonary illness) remains a common cause of morbidity and mortality in the HIV-infected population. Over the last few decades, studies have looked at the role of atypical bacterial pneumonia (i...
2017: Pneumonia
https://www.readbyqxmd.com/read/28765500/infectious-keratoconjunctivitis-and-occurrence-of-mycoplasma-conjunctivae-and-chlamydiaceae-in-small-domestic-ruminants-from-central-karakoram-pakistan
#9
Xavier Fernández-Aguilar, Luca Rossi, Óscar Cabezón, Andrea Giorgino, Isis Victoriano Llopis, Joachim Frey, Jorge Ramón López-Olvera
Infectious keratoconjunctivitis (IKC) is a contagious eye disease primarily caused by Mycoplasma conjunctivae in domestic and wild Caprinae. Chlamydophila species have also been detected in ruminants with IKC. The objectives of this study are to investigate the ocular infection of M. conjunctivae and Chlamydiaceae and assess its interaction in relation to IKC in sheep and goats from remote communities around the Central Karakoram National Park in Pakistan, performing a combination of cross-sectional and case-control study design...
September 2, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28749292/molecular-detection-of-infectious-pathogens-of-the-upper-respiratory-tract-in-captive-nondomestic-felids
#10
Valéria M Lara, Julia C Benassi, Shayne P Bisetto, Trícia M de Oliveira, Helena L Ferreira, João P Araújo Júnior, Adriano B Carregaro
Upper respiratory tract disease is a complex infectious disease process with multiple pathogens involved. Identification of infectious agents in wild animals is of great importance for wildlife conservation. The aim of this study was to evaluate the molecular detection of feline herpesvirus type 1, feline calicivirus (FCV), Bordetella bronchiseptica , Chlamydophila felis , and Mycoplasma felis using ocular and nasal swabs in three species of captive nondomestic felids. Mycoplasma felis was detected in two ocular samples of Puma concolor and in one nasal sample of one Panthera onca ...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28717130/polymicrobial-infections-in-brain-tissue-from-alzheimer-s-disease-patients
#11
Diana Pisa, Ruth Alonso, Ana M Fernández-Fernández, Alberto Rábano, Luis Carrasco
Several studies have advanced the idea that the etiology of Alzheimer's disease (AD) could be microbial in origin. In the present study, we tested the possibility that polymicrobial infections exist in tissue from the entorhinal cortex/hippocampus region of patients with AD using immunohistochemistry (confocal laser scanning microscopy) and highly sensitive (nested) PCR. We found no evidence for expression of early (ICP0) or late (ICP5) proteins of herpes simplex virus type 1 (HSV-1) in brain sections. A polyclonal antibody against Borrelia detected structures that appeared not related to spirochetes, but rather to fungi...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28678871/the-effect-of-infectious-dose-on-humoral-and-cellular-immune-responses-in-chlamydophila-caviae-primary-ocular-infection
#12
Ana Filipovic, Ehsan Ghasemian, Aleksandra Inic-Kanada, Ivana Lukic, Elisabeth Stein, Emilija Marinkovic, Radmila Djokic, Dejana Kosanovic, Nadine Schuerer, Hadeel Chalabi, Sandra Belij-Rammerstorfer, Marijana Stojanovic, Talin Barisani-Asenbauer
Following infection, the balance between protective immunity and immunopathology often depends on the initial infectious load. Several studies have investigated the effect of infectious dose; however, the mechanism by which infectious dose affects disease outcomes and the development of a protective immune response is not known. The aim of this study was to investigate how the infectious dose modulates the local and systemic humoral and the cellular immune responses during primary ocular chlamydial infection in the guinea pig animal model...
2017: PloS One
https://www.readbyqxmd.com/read/28599867/macrolide-therapy-for-community-acquired-pneumonia-due-to-atypical-pathogens-outcome-assessment-at-an-early-time-point
#13
Thomas M File, Paul B Eckburg, George H Talbot, Lily Llorens, H David Friedland
BACKGROUND: Therapy directed against atypical pathogens in patients with community-acquired pneumonia (CAP) is often recommended. This post-hoc analysis evaluated the effect of addition of a macrolide to ceftaroline fosamil or ceftriaxone treatment in atypical CAP. METHODS: Two phase 3, double-blind, comparative safety and efficacy studies of ceftaroline fosamil vs. ceftriaxone, FOCUS 1 and FOCUS 2, enrolled adults with CAP. Only FOCUS 1 included 24-h adjunctive clarithromycin therapy for all patients on day 1...
June 6, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28583026/a-prolonged-antibiotic-protocol-to-treat-persistent-chlamydophila-pneumoniae-infection-improves-the-extracranial-venous-circulation-in-multiple-sclerosis
#14
Paul Thibault, John Attia, Chris Oldmeadow
Objective Chronic cerebrospinal venous insufficiency (CCSVI) is a condition associated with multiple sclerosis (MS). One mechanism that has been proposed is that the venous obstructions found in MS are due to a chronic persistent venulitis caused by the intra-cellular bacterial parasite, Chlamydophila pneumoniae (Cpn). The objective of the current study is to determine the effect of a combined antibiotic protocol (CAP) on the venous flow in MS patients as measured by a quantitative duplex ultrasound examination (QDUS)...
January 1, 2017: Phlebology
https://www.readbyqxmd.com/read/28567210/potential-disease-transmission-from-wild-geese-and-swans-to-livestock-poultry-and-humans-a-review-of-the-scientific-literature-from-a-one-health-perspective
#15
Johan Elmberg, Charlotte Berg, Henrik Lerner, Jonas Waldenström, Rebecca Hessel
There are more herbivorous waterfowl (swans and geese) close to humans, livestock and poultry than ever before. This creates widespread conflict with agriculture and other human interests, but also debate about the role of swans and geese as potential vectors of disease of relevance for human and animal health. Using a One Health perspective, we provide the first comprehensive review of the scientific literature about the most relevant viral, bacterial, and unicellular pathogens occurring in wild geese and swans...
2017: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/28560041/severe-acute-asthma-caused-by-chlamydophila-pneumoniae-infection
#16
Yoshinari Endo, Toshihiro Shirai, Mika Saigusa, Eisuke Mochizuki
Asthma exacerbation is associated with respiratory infections, including those by viruses and atypical bacteria. We herein report a case of severe acute asthma in an adult caused by Chlamydophila pneumoniae (C. pneumoniae) infection. A 39-year-old woman without a history of asthma reported to the emergency department with progressive worsening of cough, shortness of breath, and wheezing with low oxygen saturation. A computed tomography (CT) scan revealed patchy ground-glass opacity and bronchial wall thickening...
July 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28472926/european-chlamydia-abortus-livestock-isolate-genomes-reveal-unusual-stability-and-limited-diversity-reflected-in-geographical-signatures
#17
H M B Seth-Smith, Leonor Sánchez Busó, M Livingstone, M Sait, S R Harris, K D Aitchison, Evangelia Vretou, V I Siarkou, K Laroucau, K Sachse, D Longbottom, N R Thomson
BACKGROUND: Chlamydia abortus (formerly Chlamydophila abortus) is an economically important livestock pathogen, causing ovine enzootic abortion (OEA), and can also cause zoonotic infections in humans affecting pregnancy outcome. Large-scale genomic studies on other chlamydial species are giving insights into the biology of these organisms but have not yet been performed on C. abortus. Our aim was to investigate a broad collection of European isolates of C. abortus, using next generation sequencing methods, looking at diversity, geographic distribution and genome dynamics...
May 4, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28431520/infectious-agents-is-a-risk-factor-for-myxomatous-mitral-valve-degeneration-a-case-control-study
#18
Marcos Gradim Tiveron, Pablo Maria Alberto Pomerantzeff, Maria de Lourdes Higuchi, Marcia Martins Reis, Jaqueline de Jesus Pereira, Joyce Tieko Kawakami, Renata Nishiyama Ikegami, Carlos Manuel de Almeida Brandao, Fabio Biscegli Jatene
BACKGROUND: The etiology of myxomatous mitral valve degeneration (MVD) is not fully understood and may depend on time or environmental factors for which the interaction of infectious agents has not been documented. The purpose of the study is to analyze the effect of Mycoplasma pneumoniae (Mp), Chlamydophila pneumoniae (Cp) and Borrelia burgdorferi (Bb) on myxomatous mitral valve degeneration pathogenesis and establish whether increased in inflammation and collagen degradation in myxomatous mitral valve degeneration etiopathogenesis...
April 21, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28393985/-importance-of-respiratory-virus-in-immunocompetent-adult-patients-hospitalized-with-community-acquired-pneumonia
#19
Fernando Saldías Peñafiel, Marcos Ortega Gutiérrez, Gino Fuentes López, José Manuel Elola Aránguiz, Javier Uribe Monasterio, Arturo Morales Soto, Orlando Díaz Patiño
BACKGROUND: Community-acquired pneumonia (CAP) is a relevant worldwide cause of morbidity and mortality in adult population, however its etiology is often not identified and therapy is empirical. AIM: To assess the etiology of CAP in immunocompetent adult hospitalized patients using conventional and molecular diagnostic methods. MATERIAL AND METHODS: We prospectively studied 240 adult patients who were hospitalized for CAP to identify the microbial etiology...
December 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28376442/prevalence-of-atypical-pathogens-in-patients-with-cough-and-community-acquired-pneumonia-a-meta-analysis
#20
REVIEW
Christian Marchello, Ariella Perry Dale, Thuy Nhu Thai, Duk Soo Han, Mark H Ebell
PURPOSE: Community-acquired pneumonia (CAP), acute cough, bronchitis, and lower respiratory tract infections (LRTI) are often caused by infections with viruses or Streptococcus pneumoniae. The prevalence of atypical pathogens Mycoplasma pneumoniae, Chlamydophila pneumoniae, Legionella pneumophila, and Bordetella pertussis among patients with these illnesses in the ambulatory setting has not been previously summarized. We set out to derive prevalence information from the existing literature...
November 2016: Annals of Family Medicine
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