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Peripheral IV infection

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https://www.readbyqxmd.com/read/28161606/the-absolute-number-of-regulatory-t-cells-in-unmanipulated-peripheral-blood-grafts-predicts-the-occurrence-of-acute-graft-versus-host-disease-post-haplo-identical-hematopoietic-stem-cell-transplantation
#1
Li Ding, Heng Zhu, Yang Yang, Hong-Min Yan, Hai-Hong Zhang, Dong-Mei Han, Zhi-Dong Wang, Xiao-Li Zheng, Jing Liu, Ling Zhu, Mei-Xue, Zi-Kuan Guo, Heng-Xiang Wang
CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) have been reported to play a central role in suppressing acute graft-versus-host disease (aGVHD), but whether the Treg contents of grafts correlates with the occurrence of aGVHD post haplo-identical hematopoietic stem cell transplantation (haplo-HSCT) remains unclear. In the present study, changes in Tregs in peripheral blood (PB) were followed before and after granulocyte colony-stimulating factor (G-CSF) mobilization. In addition, functional analyses of Tregs in PB grafts and bone marrow (BM) grafts were performed...
January 18, 2017: Leukemia Research
https://www.readbyqxmd.com/read/28128086/vesicular-contact-reaction-may-progress-into-erythema-multiforme
#2
Magdalena Czarnecka-Operacz, Dorota Jenerowicz, Joanna Szulczyńska-Gabor, Ewa Teresiak-Mikołajczak, Joanna Szyfter-Harris, Monika Bowszyc-Dmochowska
Dear Editor, Erythema multiforme is considered an acute skin condition, characterized by a self-limiting and sometimes recurrent course. It is regarded as a type IV hypersensitivity reaction associated with certain infections, medications, and other various triggers. Allergic contact dermatitis is in turn a delayed type of induced allergy as a result of cutaneous contact with a specific allergen to which the patient develops specific sensitivity. This type of cutaneous reaction is associated with inflammation manifesting with erythema, edema, and vesicles...
December 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28124965/-bacteremia-caused-by-ciprofloxacin-resistant-salmonella-serotype-kentucky-a-case-report-and-the-review-of-literature
#3
Tuba Müderris, Fatma Yekta Ürkmez, Şeref Alp Küçüker, Muhammet Fethi Sağlam, Gül Ruhsar Yılmaz, Rahmet Güner, Revasiye Güleşen, Ziya Cibali Açıkgöz
Salmonella infections can be seen in four clinical types, namely gastroenteritis, bacteremia/sepsis, enteric fever and carriage. These infections can result in uncomplicated diarrhea in most cases, but can lead to invasive disease requiring antimicrobial therapy and can be life-threatening in elderly or immunocomprimised patients. Broad-spectrum cephalosporins and fluoroquinolones are crucial options in the treatment of the invasive infections. Ciprofloxacin resistance is rarely seen in non-typhoid Salmonella enterica isolates, and only in S...
October 2016: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/27940065/identification-of-trypanosoma-cruzi-discrete-typing-units-dtus-in-latin-american-migrants-in-barcelona-spain
#4
Alba Abras, Montserrat Gállego, Carmen Muñoz, Natalia A Juiz, Juan Carlos Ramírez, Carolina I Cura, Silvia Tebar, Anna Fernández-Arévalo, María-Jesús Pinazo, Leonardo de la Torre, Elizabeth Posada, Ferran Navarro, Paula Espinal, Cristina Ballart, Montserrat Portús, Joaquim Gascón, Alejandro G Schijman
Trypanosoma cruzi, the causative agent of Chagas disease, is divided into six Discrete Typing Units (DTUs): TcI-TcVI. We aimed to identify T. cruzi DTUs in Latin-American migrants in the Barcelona area (Spain) and to assess different molecular typing approaches for the characterization of T. cruzi genotypes. Seventy-five peripheral blood samples were analyzed by two real-time PCR methods (qPCR) based on satellite DNA (SatDNA) and kinetoplastid DNA (kDNA). The 20 samples testing positive in both methods, all belonging to Bolivian individuals, were submitted to DTU characterization using two PCR-based flowcharts: multiplex qPCR using TaqMan probes (MTq-PCR), and conventional PCR...
April 2017: Parasitology International
https://www.readbyqxmd.com/read/27908432/safety-and-utilization-of-peripherally-inserted-central-catheters-versus-midline-catheters-at-a-large-academic-medical-center
#5
Tianyuan Xu, Lawrence Kingsley, Susan DiNucci, Gwen Messer, Jong-Hyeon Jeong, Brian Morgan, Kathleen Shutt, Mohamed H Yassin
BACKGROUND: Peripherally inserted central catheters (PICCs) are a commonly used central intravenous (IV) access device, which can be associated with significant complications. Midline catheters (MCs) are peripheral IV access devices that may reduce the need for central lines and hence decrease central line-associated bloodstream infections. The objective of this study is to compare the utilization and safety of PICCs and MCs. METHODS: This was a retrospective study comparing the use and outcomes of PICCs and MCs at a large academic medical center between January and May 2015...
December 1, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27813499/peripheral-blood-lymphocyte-subset-levels-differ-in-patients-with-hepatocellular-carcinoma
#6
Hai-Zhou Liu, Wei Deng, Ji-Lin Li, Ya-Mei Tang, Li-Tu Zhang, Ying Cui, Xin-Qiang Liang
We investigated the levels of target lymphocyte subsets in peripheral blood lymphocyte samples from patients with hepatocellular carcinoma (HCC). A total of 715 high-risk patients with primary HCC were recruited in Guangxi, China as the case group. The control group included 100 patients who received health examinations at the same hospital during the same period. Fasting elbow venous blood (10 mL) was collected from each participant, and flow cytometry was used to detect the levels of NK cells and CD3+, CD4+ and CD19+ T cells in peripheral blood samples...
November 3, 2016: Oncotarget
https://www.readbyqxmd.com/read/27734108/complications-of-intravascular-catheters-in-icu-definitions-incidence-and-severity-a-randomized-controlled-trial-comparing-usual-transparent-dressings-versus-new-generation-dressings-the-advanced-study
#7
Silvia Calviño Günther, Carole Schwebel, Rebecca Hamidfar-Roy, Agnès Bonadona, Maxime Lugosi, Claire Ara-Somohano, Clémence Minet, Leïla Potton, Jean-Charles Cartier, Aurelien Vésin, Magalie Chautemps, Lenka Styfalova, Stephane Ruckly, Jean-François Timsit
PURPOSE: To describe all post-insertion complications involving most used intravascular access, and to determine whether the use of a new-generation transparent dressing (3M™ IV Advanced) might reduce their number and impact on ICU patient outcomes. METHODS: Patients older than 18, with an expected length of stay ≥48 h and requiring at least one central venous catheter (CVC), arterial catheter (AC), haemodialysis catheter (HDC), pulmonary arterial catheters (PAC) or peripheral venous catheter (PVC) were randomized into two groups: a new-generation transparent dressing, or the hospital's classical transparent dressing, and were followed daily for any infectious and non-infectious complications...
November 2016: Intensive Care Medicine
https://www.readbyqxmd.com/read/27723246/comparison-of-five-systems-of-classification-of-diabetic-foot-ulcers-and-predictive-factors-for-amputation
#8
Byung-Joon Jeon, Hwan Jun Choi, Jin Seok Kang, Min Sung Tak, Eun Soo Park
Diabetes mellitus is a common metabolic disorder. Among various complications, diabetic neuropathy and peripheral vascular disorders are closely associated with diabetic foot ulcers (DFUs). Lower extremity ulcers and amputations are ongoing problems among individuals with diabetes. There are several classification systems for DFUs; however, no prognostic system has to date been accepted as the gold standard or the optimum prediction tool for amputations. A retrospective study was designed. Demographic data and baseline laboratory data were gathered and scored or evaluated using five representative DFU classification systems...
October 10, 2016: International Wound Journal
https://www.readbyqxmd.com/read/27625200/umbilical-cord-cd71-erythroid-cells-are-reduced-in-neonates-born-to-women-in-spontaneous-preterm-labor
#9
Nardhy Gomez-Lopez, Roberto Romero, Yi Xu, Derek Miller, Ronald Unkel, Tippi C MacKenzie, Michela Frascoli, Sonia S Hassan
PROBLEM: Preterm neonates are highly susceptible to infection. Neonatal host defense against infection seems to be maintained by the temporal presence of immunosuppressive CD71+ erythroid cells. The aim of this study was to investigate whether umbilical cord CD71+ erythroid cells are reduced in neonates born to women who undergo spontaneous preterm labor/birth. METHOD OF STUDY: Umbilical cord blood samples (n=155) were collected from neonates born to women who delivered preterm with (n=39) and without (n=12) spontaneous labor or at term with (n=82) and without (n=22) spontaneous labor...
October 2016: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/27555533/allogeneic-hematopoietic-stem-cell-transplantation-in-thirty-four-pediatric-cases-of-mucopolysaccharidosis-a-ten-year-report-from-the-china-children-transplant-group
#10
Jianmin Wang, Zuo Luan, Hua Jiang, Jianpei Fang, Maoquan Qin, Vincent Lee, Jing Chen
We investigated the efficacy of allogeneic hematopoietic stem cell transplantation (alloHSCT) in pediatric patients with mucopolysaccharidosis (MPS). A retrospective analysis of transplantation data from 34 cases of MPS from the China Children Transplant Group, treated between December 2004 and September 2015, was conducted. Among the 34 cases, 12 cases were type I, 12 were type II, 4 were type IV, 4 were type VI, and 2 were of an unknown type. The median age at transplantation was 3.75 years (range, 1 to 7 years); the median follow-up time was 14 months (range, 2 to 119 months)...
November 2016: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/27512714/ganciclovir-use-evaluation-in-kidney-transplantation-departments
#11
Maryam Mozaffar, Shahrzad Shahidi, Shirinsadat Badri
OBJECTIVE: In this study, we evaluated certain aspects of the usage and administration of one lifesaving, high-cost medication, i.e., Ganciclovir for the prevention and treatment of cytomegalovirus (CMV) infection in transplant patients. METHODS: This study was performed from 2013 to 2015 by conducting a medication use evaluation (MUE) program in the kidney transplantation departments of two tertiary care hospitals in Isfahan, Iran. The MUE criteria for the drug were developed by applying drug information references...
July 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27401772/mini-invasive-floating-metatarsal-osteotomy-for-resistant-or-recurrent-neuropathic-plantar-metatarsal-head-ulcers
#12
Eran Tamir, Aharon S Finestone, Erez Avisar, Gabriel Agar
BACKGROUND: Patients with peripheral neuropathy and pressure under a relatively plantar deviated metatarsal head frequently develop plantar foot ulcers. When conservative management with orthotics and shoes does not cure the ulcer, surgical metatarsal osteotomy may be indicated to relieve the pressure and enable the ulcer to heal. The purpose of this study is to evaluate the use of a mini-invasive floating metatarsal osteotomy in treating recalcitrant ulcers or recurrent ulcers plantar to the metatarsal heads in patients with diabetes mellitus (DM) related neuropathy...
July 11, 2016: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/27399076/mortality-following-snake-bite-envenomation-by-bitis-arietans-in-an-hiv-positive-child-a-case-report
#13
Gregory B Firth, Matthew Street, Yammesh Ramguthy, Linda Doedens
Snake bites occur commonly in the rural areas of South Africa. Hospitals where snake bites are uncommon should always have protocols on standby in the event of such cases presenting. This is the first reported case documenting the effect of human immunodeficiency virus (HIV) on snake bite in South African children.A case report and review of relevant information about the case was undertaken.We present a case of a 1-year-old child referred from a peripheral hospital following a snake bite to the left upper limb with a compartment syndrome and features of cytotoxic envenomation...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27275160/risk-factors-for-acute-kidney-injury-after-cardiovascular-surgery-evidence-from-2-157-cases-and-49-777-controls-a-meta-analysis
#14
Qian Yi, Ke Li, Zhao Jian, Ying-Bin Xiao, Lin Chen, Yao Zhang, Rui-Yan Ma
PURPOSE: Cardiovascular surgery-associated acute kidney injury (AKI-CS) contributes to mortality and morbidity. However, risk factors accelerating its development are unclear. We identified risk factors for AKI-CS in patients with cardiopulmonary bypass in the hospital surgical intensive care unit to predict and minimize renal complication in future cardiac surgery. METHODS: We analyzed data from 14 case-control studies published prior to June 2014 and indexed in Science Citation Index, PubMed, and other databases to determine the major risk factors for AKI-CS...
May 2016: Cardiorenal Medicine
https://www.readbyqxmd.com/read/27153143/use-of-the-modified-frailty-index-to-predict-30-day-morbidity-and-mortality-from-spine-surgery
#15
Rushna Ali, Jason M Schwalb, David R Nerenz, Heath J Antoine, Ilan Rubinfeld
OBJECTIVE Limited tools exist to stratify perioperative risk in patients undergoing spinal procedures. The modified frailty index (mFI) based on the Canadian Study of Health and Aging Frailty Index (CSHA-FI), constructed from standard demographic variables, has been applied to various other surgical populations for risk stratification. The authors hypothesized that it would be predictive of postoperative morbidity and mortality in patients undergoing spine surgery. METHODS The 2006-2010 National Surgical Quality Improvement Program (NSQIP) data set was accessed for patients undergoing spine surgeries based on Current Procedural Terminology (CPT) codes...
October 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27123854/pathological-roles-of-interleukin-22-in-the-development-of-recurrent-hepatitis-c-after-liver-transplantation
#16
Yinjie Gao, Hui Ren, Fanping Meng, Jin Li, Eddie Cheung, Hanwei Li, Jingmin Zhao, Hongling Liu, Zhenwen Liu, Min Zhang
OBJECTIVE: The aim of this study was to longitudinally evaluate and analyze the role of interleukin-22-producing CD4 positive cells (IL-22) in the pathogenesis of Hepatitis C Virus recurrence after Orthotopic Liver Transplantation (HCV-OLT). METHODS: 15 HCV-OLT, 15 age- and gender- matched non-HCV post-OLT (OLT) and 15 hepatitis C virus infected (HCV) patients were enrolled into our study from the liver transplantation and research center at Beijing 302 Hospital...
2016: PloS One
https://www.readbyqxmd.com/read/27107290/rhizobium-radiobacter-infection-in-a-27-year-old-african-american-woman-with-munchausen-syndrome
#17
Sameer Sawhney, Tammey Naab, Partricia Oneal
Rhizobium radiobacter is an opportunistic, usually saprophytic, gram-negative bacillus found in agricultural soil. Isolation from blood has been reported most often in hospitalized patients harboring malignant neoplasms or human immunodeficiency virus (HIV) associated immunosuppression, who have catheter or medical device-related febrile neutropenia; treatment involves removal of the catheter or implanted medical device.(1)Herein, we report a case of a 27-year-old African American woman with sickle cell anemia who sought treatment of generalized body pain, shaking, chills, dyspnea, and fever, suggestive of sickle cell crisis...
August 2016: Laboratory Medicine
https://www.readbyqxmd.com/read/27097224/elevation-of-non-classical-cd14-lowcd16-monocytes-is-associated-with-increased-albuminuria-and-urine-tgf-%C3%AE-1-in-hiv-infected-individuals-on-stable-antiretroviral-therapy
#18
Brooks I Mitchell, Mary Margaret Byron, Roland C Ng, Dominic C Chow, Lishomwa C Ndhlovu, Cecilia M Shikuma
OBJECTIVE: High rates of albuminuria are observed among HIV-infected individuals on stable antiretroviral therapy (ART). Though pro-inflammatory and pro-fibrotic responses are described as components of albuminuria in the general population, it is unclear how these responses are associated to albuminuria in ART-treated chronic HIV. We investigated the relationship of monocyte subsets and urine inflammatory and fibrotic biomarkers to albuminuria in ART-treated HIV-infected participants...
2016: PloS One
https://www.readbyqxmd.com/read/27068663/perforator-based-island-flap-with-a-peripheral-muscle-patch-for-coverage-of-sacral-sores
#19
Jung Woo Chang, Jang Hyun Lee, Matthew Seung Suk Choi
Despite numerous therapeutic advances, the treatment of pressure sores remains a challenge. The increased use of perforator flaps enables surgeons to minimize donor-site morbidity by sparing the underlying muscle. In the presence of focal deep spaces, however, the inclusion of muscle would be beneficial. The goal of this study was to introduce a method for including a muscle patch at the periphery of a perforator-based island flap for coverage of sacral pressure sores. Between March 2010 and February 2015, 26 patients with stage IV sacral sores underwent perforator-based island flap reconstruction with a peripheral muscle patch...
June 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27056672/sepsis-induced-long-term-immune-paralysis-results-of-a-descriptive-explorative-study
#20
C Arens, S A Bajwa, C Koch, B H Siegler, E Schneck, A Hecker, S Weiterer, C Lichtenstern, M A Weigand, F Uhle
BACKGROUND: Long-lasting impairment of the immune system is believed to be the underlying reason for delayed deaths after surviving sepsis. We tested the hypothesis of persisting changes to the immune system in survivors of sepsis for the first time. METHODS: In our prospective, cross-sectional pilot study, eight former patients who survived catecholamine-dependent sepsis and eight control individuals matched for age, sex, diabetes and renal insufficiency were enrolled...
February 29, 2016: Critical Care: the Official Journal of the Critical Care Forum
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