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Sleep apnoea

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https://www.readbyqxmd.com/read/28211952/long-term-experience-with-first-generation-implantable-neurostimulation-device-in-central-sleep-apnea-treatment
#1
Henrik Fox, Thomas Bitter, Dieter Horstkotte, Olaf Oldenburg, Klaus-Jürgen Gutleben
BACKGROUND: Sleep-disordered breathing (SDB) and Cheyne-Stokes respiration (CSR) are associated with shorter survival in patients with heart failure (HF). A novel treatment method for this patient group is unilateral phrenic nerve stimulation by the remedē® system, a transvenously implantable neurostimulation device, which has recently been studied in a large randomized, controlled trial. Previous literature has shown efficacy and safety of the treatment with this first-generation device, but hardly any data is available on long-term clinical parameters, the remedē® device's battery lifetime, device exchangeability, lead position stability, surgical accessibility and manageability...
February 17, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28210922/resting-cerebral-blood-flow-alteration-in-severe-obstructive-sleep-apnoea-an-arterial-spin-labelling-perfusion-fmri-study
#2
Si Nie, De-Chang Peng, Hong-Han Gong, Hai-Jun Li, Li-Ting Chen, Cheng-Long Ye
STUDY OBJECTIVES: The aim of this study is to investigate changes in regional cerebral blood flow (rCBF) in awake people with untreated severe obstructive sleep apnoea (OSAs) compared with good sleepers (GSs). DESIGN: Arterial spin labelling perfusion imaging was used to quantify cerebral perfusion based on resting-state functional magnetic resonance imaging (MRI). SETTING: Lying supine in a 3.0-T magnetic resonance imaging scanner in the night was done...
February 16, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28210325/hot-topics-from-the-assemblies
#3
(no author information available yet)
Cowie et al. present the results of the international, multicentre, randomised, parallel-group SERVE-HF (Treatment of sleep-disordered breathing with predominant central sleep apnea by adaptive servo ventilation in patients with heart failure) trial, which investigated the effects of adding adaptive servo-ventilation (ASV) to guideline based medical management on survival and cardiovascular outcomes in patients with heart failure defined as reduced ejection fraction (<45%) and predominant central sleep apnoea (CSA)...
December 2016: Breathe
https://www.readbyqxmd.com/read/28210297/should-the-diagnosis-and-management-of-osa-move-into-general-practice
#4
REVIEW
Monique Suárez, Jeisson Osorio, Marta Torres, Josep M Montserrat
Sleep apnoea is a common disease that for accurate management requires the participation of primary care medicine http://ow.ly/G6Mq301zcaM.
September 2016: Breathe
https://www.readbyqxmd.com/read/28198598/coblation-%C3%A2-intracapsular-tonsillectomy-tonsillotomy-in-children-a-prospective-study-of-500-consecutive-cases-with-long-term-follow-up
#5
A W Hoey, N M Foden, S Hadjisymeou Andreou, F Noonan, A K Chowdhury, Greig S R, E L Sproson, D Allin, N Amin, K M Wouters, N E Jonas, D J Tweedie
OBJECTIVES: Intracapsular tonsillectomy (tonsillotomy) has been used internationally, mainly in the management of obstructive sleep apnoea, rather than recurrent tonsillitis, with little published data evaluating its use for this latter indication. We present long-term prospective data from 500 paediatric cases undergoing Coblation(®) intracapsular tonsillectomy, for both obstructive and infective indications. DESIGN: Prospective case series, March 2013-January 2016, all with completed follow up...
February 15, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28198530/location-of-the-narrowest-area-of-the-pharynx-regarding-bmi-and-osa-severity
#6
Marta Krasny, Jarosław Wysocki, Monika Prus, Kazimierz Niemczyk
BACKGROUND: Among authors studying morphological determinants of the Obstructive Sleep Apnoea (OSA) controversies exist on the location of the narrowest area within the pharynx critical for development of obstruction. Those disagreements primarily revolve around differences between obese and nonobese OSA patients. Determination whether the location and size of the narrowest area within the pharynx differentiates the obese and nonobese OSA patients. MATERIALS AND METHODS: A population of 55 subjects was investigated after being diagnosed with OSA in the Polysomnography Laboratory of the Department and Clinic of Otolaryngology in the Medical University of Warsaw...
February 15, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28198129/beyond-the-thermistor-novel-technology-for-the-ambulatory-diagnosis-of-obstructive-sleep-apnoea
#7
EDITORIAL
Emma L Gray, David J Barnes
No abstract text is available yet for this article.
February 14, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28194236/european-union-directive-2014-85-eu-on-driver-licensing-in-obstructive-sleep-apnoea-early-experiences-with-its-application-in-the-uk
#8
EDITORIAL
Dipansu Ghosh, Thomas W Mackay, Renata L Riha
OSA patients' risk of RTA should be assessed using detailed driving history with specific focus on "red flags" http://ow.ly/mxPi305isni.
September 2016: Breathe
https://www.readbyqxmd.com/read/28193305/tongue-lip-adhesion-and-tongue-repositioning-for-obstructive-sleep-apnoea-in-pierre-robin-sequence-a-systematic-review-and-meta-analysis
#9
M Camacho, M W Noller, S Zaghi, L K Reckley, C Fernandez-Salvador, E Ho, B Dunn, D K Chan
OBJECTIVE: To search for studies on tongue-lip adhesion and tongue repositioning used as isolated treatments for obstructive sleep apnoea in children with Pierre Robin sequence. METHODS: A systematic literature search of PubMed/Medline and three additional databases, from inception through to 8 July 2016, was performed by two authors. RESULTS: Seven studies with 90 patients (59 tongue-lip adhesion and 31 tongue repositioning patients) met the inclusion criteria...
February 14, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28190618/excessive-daytime-sleepiness-does-not-correlate-with-sympathetic-nervous-system-activation-and-arterial-stiffening-in-patients-with-mild-to-moderate-obstructive-sleep-apnoea-a-proof-of-principle-study
#10
Valeria Bisogni, Martino F Pengo, Panagis Drakatos, Giuseppe Maiolino, Brian Kent, Giacomo Rossitto, Joerg Steier, Gian Paolo Rossi
BACKGROUND: Increased arterial stiffness and sympathetic nervous system activity, independent markers of cardiovascular risk, are common in patients with severe obstructive sleep apnoea, who have excessive daytime sleepiness. Among patients with mild-to-moderate obstructive sleep apnoea, however, it remains unknown whether arterial stiffness and/or increased sympathetic nervous system activity correlate with excessive daytime sleepiness. METHODS: We measured heart rate variability, as an index of autonomic nervous system activity, and arterial stiffness index, as a marker of vascular damage and cardiovascular risk, in 56 men aged 18 to 75years, with mild-to-moderate obstructive sleep apnoea, and matched into two groups, "sleepy" (Epworth Sleepiness Scale≥10) and "non-sleepy" (Epworth Sleepiness Scale<10)...
February 2, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28185772/impact-of-weight-loss-management-in-osa
#11
REVIEW
Simon A Joosten, Garun S Hamilton, Matthew T Naughton
The interaction between obesity and obstructive sleep apnea (OSA) is complex. Whilst it is often assumed that obesity is the major cause of OSA, and that treatment of the OSA might mitigate further weight gain, new evidence is emerging that suggest these statements may not be the case. Obesity explains about 60% of the variance of the apnea hypopnea index definition of OSA, mainly in those < 50 years and less so in the elderly. Moreover, long term treatment of OSA with continuous positive airway pressure is associated with small but significant weight gain...
February 6, 2017: Chest
https://www.readbyqxmd.com/read/28185594/sleep-apnoea-in-australian-men-disease-burden-co-morbidities-and-correlates-from-the-australian-longitudinal-study-on-male-health
#12
Chamara Visanka Senaratna, Dallas R English, Dianne Currier, Jennifer L Perret, Adrian Lowe, Caroline Lodge, Melissa Russell, Sashane Sahabandu, Melanie C Matheson, Garun S Hamilton, Shyamali C Dharmage
BACKGROUND: Obstructive sleep apnoea is a common disorder with under-rated clinical impact, which is increasingly being recognised as having a major bearing on global disease burden. Men are especially vulnerable and become a priority group for preventative interventions. However, there is limited information on prevalence of the condition in Australia, its co-morbidities, and potential risk factors. METHODS: We used data from 13,423 adult men included in the baseline wave of Ten to Men, an Australian national study of the health of males, assembled using stratified cluster sampling with oversampling from rural and regional areas...
October 31, 2016: BMC Public Health
https://www.readbyqxmd.com/read/28181680/early-term-deliveries-and-the-risk-of-pediatric-obstructive-sleep-apnoea-in-the-offspring
#13
Asnat Walfisch, Tamar Wainstock, Ofer Beharier, Daniella Landau, Eyal Sheiner
BACKGROUND: Preterm delivery may affect the development of the upper airways resulting in a higher risk of obstructive sleep apnoea (OSA). We investigated whether children born at early term (37-38 6/7 weeks' gestation) are at an increased risk for childhood OSA as compared with those born later. METHODS: In this population-based cohort analysis all singleton deliveries occurring between 1991-2013 at a single regional tertiary medical centre were included. Gestational age upon delivery was sub-divided into: early preterm (<33 6/7 weeks' gestation), late preterm (34-36 6/7), early term, full term (39-40 6/7), late term (41-41 6/7), and post term (>42 0/7)...
February 9, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28181463/reproducibility-of-an-extensive-self-report-questionnaire-used-in-secondary-coronary-prevention
#14
Kari Peersen, John Munkhaugen, Lars Gullestad, Toril Dammen, Torbjorn Moum, Jan Erik Otterstad
AIMS: Self-reported information from questionnaires is frequently used in clinical epidemiological studies, but few provide information on the reproducibility of instruments applied in secondary coronary prevention studies. This study aims to assess the test-retest reproducibility of the questionnaire applied in the cross-sectional NORwegian CORonary (NOR-COR) Prevention Study. METHODS: In the NOR-COR study 1127 coronary heart disease (CHD) patients completed a self-report questionnaire consisting of 249 questions, of which there are both validated instruments and de novo questions...
January 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28179438/management-of-continuous-positive-airway-pressure-treatment-compliance-using-telemonitoring-in-obstructive-sleep-apnoea
#15
Cecilia Turino, Jordi de Batlle, Holger Woehrle, Ana Mayoral, Anabel Lourdes Castro-Grattoni, Sílvia Gómez, Mireia Dalmases, Manuel Sánchez-de-la-Torre, Ferran Barbé
Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnoea (OSA), but treatment compliance is often unsatisfactory. This study investigated the efficacy and cost-effectiveness of telemonitoring for improving CPAP compliance.100 newly diagnosed OSA patients requiring CPAP (apnoea-hypopnoea index >15 events·h(-1)) were randomised to standard management or a telemonitoring programme that collected daily information about compliance, air leaks and residual respiratory events, and initiated patient contact to resolve issues...
February 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28177332/a-comparative-study-on-oxidative-stress-role-in-nasal-breathing-impairment-and-obstructive-sleep-apnoea-syndrome
#16
D Passali, G Corallo, A Petti, M Longini, F M Passali, G Buonocore, L M Bellussi
Obstructive sleep apnoea syndrome (OSAS) is a sleep disorder that leads to metabolic abnormalities and increased cardiovascular risk. This study aimed to define the expression and clinical significance of biomarkers involved in oxidative stress in patients with OSAS. A prospective study was designed to compare outcomes of oxidative stress laboratory tests in three groups of subjects. The study involved the recruitment of three groups of subjects, 10 patients with obstructive sleep apnoea syndrome with AHI > 30; 10 patients suffering from snoring at night with AHI < 15; 10 patients with nasal respiratory impairment with AHI < 5...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28176221/pegvisomant-in-acromegaly-an-update
#17
REVIEW
A Giustina, G Arnaldi, F Bogazzi, S Cannavò, A Colao, L De Marinis, E De Menis, E Degli Uberti, F Giorgino, S Grottoli, A G Lania, P Maffei, R Pivonello, E Ghigo
BACKGROUND: In 2007, we published an opinion document to review the role of pegvisomant (PEG) in the treatment of acromegaly. Since then, new evidence emerged on the biochemical and clinical effects of PEG and on its long-term efficacy and safety. AIM: We here reviewed the emerging aspects of the use of PEG in clinical practice in the light of the most recent literature. RESULTS: The clinical use of PEG is still suboptimal, considering that it remains the most powerful tool to control IGF-I in acromegaly allowing to obtain, with a pharmacological treatment, the most important clinical effects in terms of signs and symptoms, quality of life and comorbidities...
February 7, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28173893/sleep-and-circadian-rhythm-disturbance-in-bipolar-disorder
#18
A J Bradley, R Webb-Mitchell, A Hazu, N Slater, B Middleton, P Gallagher, H McAllister-Williams, K N Anderson
BACKGROUND: Subjective reports of insomnia and hypersomnia are common in bipolar disorder (BD). It is unclear to what extent these relate to underlying circadian rhythm disturbance (CRD). In this study we aimed to objectively assess sleep and circadian rhythm in a cohort of patients with BD compared to matched controls. METHOD: Forty-six patients with BD and 42 controls had comprehensive sleep/circadian rhythm assessment with respiratory sleep studies, prolonged accelerometry over 3 weeks, sleep questionnaires and diaries, melatonin levels, alongside mood, psychosocial functioning and quality of life (QoL) questionnaires...
February 8, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28168335/at-home-pulse-oximetry-in-children-undergoing-adenotonsillectomy-for-obstructive-sleep-apnea
#19
Martino Pavone, Nicola Ullmann, Elisabetta Verrillo, Giancarlo De Vincentiis, Emanuela Sitzia, Renato Cutrera
: Nocturnal pulse oximetry has a high positive predictive value for polysomnographically diagnosed obstructive sleep apnoea (OSA) in children. When significant adenotonsillar hypertrophy is diagnosed, adenotonsillectomy (T&A) represents a common treatment for OSA in children. We investigated the role of pulse oximetry in predicting those patients, referred for suspected OSA, who subsequently needed T&A. At-home nocturnal pulse oximetry was performed on 380 children (65.7% males), median age 4...
February 6, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28166999/unresolved-drooling-in-a-previously-healthy-child-caused-by-a-brainstem-malignancy
#20
Fenella Shelton, Eleanor Sproson, Jana Van der Veen, Hazel Evans, Andrea Burgess, Hasnaa Ismail-Koch
Drooling occurs commonly in children below the age of two. In a small group of children this persists and an otorhinolaryngology consultation is sought. In children with no neurological abnormality or comorbidity, reassurance and behavioural management is often suggested. We present a case where drooling was the presenting feature of brain stem malignancy. Diagnosis was suggested following a sleep study demonstrating central apnoeas. Magnetic resonance imaging (MRI) showed an intra-axial brainstem tumour. This case highlights the importance of multidisciplinary team (MDT) management of children with persistent drooling of unknown cause...
March 2017: International Journal of Pediatric Otorhinolaryngology
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