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https://www.readbyqxmd.com/read/28535580/gastroparesis-updates-on-pathogenesis-and-management
#1
REVIEW
Nanlong Liu, Thomas Abell
Gastroparesis (Gp) is a chronic disease that presents with clinical symptoms of early satiety, bloating, nausea, vomiting, and abdominal pain. Along with these symptoms, an objective finding of delayed gastric emptying, along with a documented absence of gastric outlet obstruction, are required for diagnosis. This article focuses on updates in the pathogenesis and management of Gp. Recent studies on full thickness biopsies of Gp patients have shed light on the complex interactions of the central, autonomic, and enteric nervous systems, which all play key roles in maintaining normal gut motility...
May 25, 2017: Gut and Liver
https://www.readbyqxmd.com/read/28534060/food-swamps-by-area-socioeconomic-deprivation-in-new-zealand-a-national-study
#2
Zaynel Sushil, Stefanie Vandevijvere, Daniel J Exeter, Boyd Swinburn
OBJECTIVES: A nationwide spatial analysis of community retail food environments in relation to area socioeconomic deprivation was conducted in New Zealand. METHODS: Addresses from about 20,000 registered food outlets were retrieved from all 66 Councils. Outlets were classified, geocoded and (spatially) validated. The analysis included 4087 convenience, 4316 fast food/takeaway and 1271 supermarket and fruit/vegetable outlets and excluded outlets not considered 'healthy' or 'unhealthy'...
May 22, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28530097/total-particle-number-emissions-from-modern-diesel-natural-gas-and-hybrid-heavy-duty-vehicles-during-on-road-operation
#3
Tianyang Wang, David Christopher Quiros, Arvind Thiruvengadam, Saroj Pradhan, Shaohua Hu, Tao Huai, Eon S Lee, Yifang Zhu
Particle emissions from heavy-duty vehicles (HDVs) have significant environmental and public health impacts. This study measured total particle number emission factors (PNEFs) from six newly-certified HDVs powered by diesel and compressed natural gas totaling over 6,800 miles of on-road operation in California. Distance-, fuel- and work-based PNEFs were calculated for each vehicle. Distance-based PNEFs of vehicles equipped with original equipment manufacturer (OEM) diesel particulate filters (DPFs) in this study have decreased by 355-3200 times compared to a previous retrofit DPF dynamometer study...
May 22, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28528771/comparison-of-residual-napl-source-removal-techniques-in-3d-metric-scale-experiments
#4
O Atteia, F Jousse, G Cohen, P Höhener
This study compared four treatment techniques for the removal of a toluene/n-decane as NAPL (Non Aqueous Phase Liquid) phase mixture in identical 1 cubic meter tanks filled with different kind of sand. These four treatment techniques were: oxidation with persulfate, surfactant washing with Tween80®, sparging with air followed by ozone, and thermal treatment at 80°C. The sources were made with three lenses of 26×26×6.5cm, one having a hydraulic conductivity similar to the whole tank and the two others a value 10 times smaller...
April 21, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/28528718/double-outlet-right-ventricle-revisited
#5
Ameneh Ebadi, Diane E Spicer, Carl L Backer, F Jay Fricker, Robert H Anderson
OBJECTIVES: Double-outlet right ventricle is a form of ventriculoarterial connection. The definition formulated by the International Society for Nomenclature of Paediatric and Congenital Heart Disease is based on hearts with both arterial trunks supported in their greater part by a morphologically right ventricle. Bilateral infundibula and ventricular septal defects are highly debated criteria. This study examines the anatomic controversies surrounding double-outlet right ventricle. We show that hearts with double-outlet right ventricle can have atrioventricular-to-arterial valvular continuity...
March 23, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28527961/major-aortopulmonary-collateral-arteries-with-anatomy-other-than-pulmonary-atresia-ventricular-septal-defect
#6
William L Patrick, Richard D Mainwaring, Olaf Reinhartz, Rajesh Punn, Theresa Tacy, Frank L Hanley
BACKGROUND: Major aortopulmonary collateral arteries (MAPCAs) are frequently found in association with pulmonary atresia with ventricular septal defect (PA/VSD). However, some patients with MAPCAs do not have PA/VSD but have a variety of other "atypical" anatomic diagnoses. METHODS: This was a retrospective review of patients with MAPCAs and atypical anatomy. The 50 patients with MAPCAs could be divided into two subgroups: (1) single ventricle anatomy (n = 33) and (2) two ventricle anatomy (n = 17)...
May 17, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28527618/giving-the-tap-the-elbow-an-observational-study
#7
M Weinbren, L Bree, S Sleigh, M Griffiths
Hand washing is viewed as the most important barrier to cross infection. Incorrect use of clinical hand wash basins may lead to cross infection either from contaminated water or due to failure to decontaminate hands. Elbow operated taps used correctly prevent re-contamination of hands during operation. Observation shows many elbow operated taps are installed incorrectly with the handle flush with the back panel making it difficult to open using the elbow. AIM: To determine the effect of altering the angle of the handle of elbow operated taps on hand washing technique...
May 17, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28526075/testing-times-trends-in-availability-price-and-market-share-of-malaria-diagnostics-in-the-public-and-private-healthcare-sector-across-eight-sub-saharan-african-countries-from-2009-to-2015
#8
Kara Hanson, Catherine Goodman
BACKGROUND: The World Health Organization guidelines have recommended that all cases of suspected malaria should receive a confirmatory test with microscopy or a malaria rapid diagnostic test (RDT), however evidence from sub-Saharan Africa (SSA) illustrates that only one-third of children under five with a recent fever received a test. The aim of this study was to evaluate availability, price and market share of microscopy and RDT from 2009/11 to 2014/15 in 8 SSA countries, to better understand barriers to improving access to malaria confirmatory testing in the public and private health sectors...
May 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28526005/validation-of-commercial-business-lists-as-a-proxy-for-licensed-alcohol-outlets
#9
Heather A Carlos, Joy Gabrielli, James D Sargent
BACKGROUND: Studies of retail alcohol outlets are restricted to regions due to lack of U.S. national data. Commercial business lists (BL) offer a possible solution, but no data exists to determine if BLs could serve as an adequate proxy for license data. This paper compares geospatial measures of alcohol outlets derived from a commercial BL with license data for a large US state. METHODS: We validated BL data as a measure of off-premise alcohol outlet density and proximity compared to license data for 5528 randomly selected California residential addresses...
May 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28521811/the-malaria-testing-and-treatment-landscape-in-mainland-tanzania-2016
#10
Daniel Michael, Sigsbert Patila Mkunde
BACKGROUND: Understanding the key characteristics of malaria testing and treatment is essential to the control of a disease that continues to pose a major risk of morbidity and mortality in mainland Tanzania, with evidence of a resurgence of the disease in recent years. The introduction of artemisinin combination therapy (ACT) as the first-line treatment for malaria, alongside policies to promote rational case management following testing, highlights the need for evidence of anti-malarial and testing markets in the country...
April 24, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28520856/control-of-multidrug-resistant-pseudomonas-aeruginosa-in-allogeneic-hematopoietic-stem-cell-transplant-recipients-by-a-novel-bundle-including-remodeling-of-sanitary-and-water-supply-systems
#11
A Kossow, S Kampmeier, S Willems, W E Berdel, A H Groll, B Burckhardt, Rossig C, C Groth, E A Idelevich, F Kipp, A Mellmann, M Stelljes
Background.: Infections by multidrug-resistant Pseudomonas aeruginosa (MDRPa) are an important cause of morbidity and mortality in patients after allogeneic hematopoietic stem cell transplantation (HSCT). Humid environments can serve as a reservoir and source of infection by this pathogen. To minimize the risk of infection from these reservoirs, we performed extensive remodeling of sanitation and water installations as the focus of our hygiene bundle. Methods.: During the reconstruction of our transplantation unit (April 2011- April 2014) we implemented several technical modifications to reduce environmental contamination by and subsequent spreading of MDRPa, including a newly designed shower drain, disinfecting siphons underneath the sinks, and rimless toilets...
May 18, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28518071/nerve-sparing-mid-urethral-obstruction-nemo-in-female-small-rodents
#12
Martin Sidler, Karen J Aitken, Jia Xin Jiang, Darius J Bägli
Partial bladder outlet obstruction (pBOO) has a high prevalence, causes significant patient burden, and immense health care costs. The most common animal model to investigate bladder remodeling in pBOO are female rodents undergoing partial obstruction at the proximal urethra. Variability in the degree of obstruction and animal mortality are major concerns with proximal obstruction. Furthermore, dissecting around the proximal urethra and bladder neck jeopardizes bladder innervation. We developed a nerve-sparing mid-urethral obstruction (NeMO) model for pBOO avoiding the disadvantages of the traditional model...
April 25, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28516796/legionella-spp-in-dental-unit-waterlines
#13
E Sedlata Juraskova, H Sedlackova, J Janska, O Holy, I Lalova, I Matouskova
OBJECTIVE: To determine the current presence of Legionella spp. in the output water of dental unit waterlines (DUWLs) and examine its mitigation by disinfection at the Institute of Dentistry and Oral Sciences, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc. MATERIAL AND METHODS: The first stage of our survey involved collecting samples of DUWL output water from 50 dental chair units (DCUs), and 2 samples of the incoming potable water...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28512388/insufficient-humidification-of-respiratory-gases-in-patients-who-are-undergoing-therapeutic-hypothermia-at-a-paediatric-and-adult-intensive-care-unit
#14
Yukari Tanaka, Sachiko Iwata, Masahiro Kinoshita, Kennosuke Tsuda, Shoichiro Tanaka, Naoko Hara, Ryota Shindou, Eimei Harada, Ryouji Kijima, Osamu Yamaga, Hitoe Ohkuma, Kazuo Ushijima, Teruo Sakamoto, Yushiro Yamashita, Osuke Iwata
For cooled newborn infants, humidifier settings for normothermic condition provide excessive gas humidity because absolute humidity at saturation is temperature-dependent. To assess humidification of respiratory gases in patients who underwent moderate therapeutic hypothermia at a paediatric/adult intensive care unit, 6 patients were studied over 9 times. Three humidifier settings, 37-default (chamber-outlet, 37°C; Y-piece, 40°C), 33.5-theoretical (chamber-outlet, 33.5°C; Y-piece, 36.5°C), and 33.5-adjusted (optimised setting to achieve saturated vapour at 33...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/28510536/effect-of-nanostructures-orientation-on-electroosmotic-flow-in-a-microfluidic-channel
#15
An Eng Lim, Chun Yee Lim, Yee Cheong Lam, Rafael Taboryski, Shu Rui Wang
Electroosmotic flow (EOF) is an electric-field-induced fluid flow that has numerous micro-/nanofluidic applications, ranging from pumping to chemical and biomedical analyses. Nanoscale networks/structures are often integrated in microchannels for a broad range of applications, such as electrophoretic separation of biomolecules, high reaction efficiency catalytic microreactors, and enhancement of heat transfer and sensing. Their introduction has been known to reduce EOF. Hitherto, a proper study on the effect of nanostructures orientation on EOF in a microfluidic channel is yet to be carried out...
May 16, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28506895/the-node-and-beyond-using-social-media-in-cell-and-developmental-biology
#16
REVIEW
Catarina Vicente, Aidan Maartens, Katherine Brown
Traditionally, strong scientific communities have been at least partly built around physical proximity - either by members of the same department or institute, or through regular meetings and conferences. The online environment and the rise of social media platforms now make it easier to build virtual communities of geographically dispersed people with a common interest. In this article, we explore how such networks can be nurtured, focussing on the Node - a community blog for and by developmental biologists...
May 12, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28506859/the-obstructed-bladder-expression-of-collagen-matrix-metalloproteinases-muscarinic-receptors-angiogenic-and-neurotrophic-factors-in-patients-with-benign-prostatic-hyperplasia
#17
João Arthur Brunhara Alves Barbosa, Sabrina T Reis, Marco Nunes, Yuri A Ferreira, Katia R Leite, William C Nahas, Miguel Srougi, Alberto A Antunes
OBJECTIVE: to evaluate gene expression of Collagen, Matrix Metalloproteinases (MMP) and Inhibitors, Cholinergic Muscarinic Receptors (CHRM), Angiogenic and Nerve Growth Factors (NGF) in the bladder of patients with Bladder Outlet Obstruction due to Benign Prostatic Hyperplasia METHODS: We analyzed bladder specimens from 43 patients with obstructive BPH undergoing TURP as compared to 10 age-matched controls with IPSS<8 and prostate <30g. A bladder biopsy was performed for relative gene expression analysis with qRT-PCR of Collagens I and III, MMPs 1,2,9; Tissue Inhibitors of Metalloproteinases (TIMP) 1,2 and RECK; CHRM2 and -3; VEGF, CD105; NGF and NGF receptor...
May 12, 2017: Urology
https://www.readbyqxmd.com/read/28506234/anti-malarial-medicine-quality-field-studies-and-surveys-a-systematic-review-of-screening-technologies-used-and-reporting-of-findings
#18
REVIEW
Mirza Lalani, Freddy Eric Kitutu, Siân E Clarke, Harparkash Kaur
BACKGROUND: Assessing the quality of medicines in low-middle income countries (LMICs) relies primarily on human inspection and screening technologies, where available. Field studies and surveys have frequently utilized screening tests to analyse medicines sampled at the point of care, such as health care facilities and medicine outlets, to provide a snap shot of medicine quality in a specific geographical area. This review presents an overview of the screening tests typically employed in surveys to assess anti-malarial medicine quality, summarizes the analytical methods used, how findings have been reported and proposes a reporting template for future studies...
May 15, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28506222/computational-fluid-dynamics-study-of-intra-arterial-chemotherapy-for-oral-cancer
#19
Hiroaki Kitajima, Marie Oshima, Toshinori Iwai, Yoshihito Ohhara, Yasuharu Yajima, Kenji Mitsudo, Iwai Tohnai
BACKGROUND: Intra-arterial chemotherapy (IAC) for oral cancer can deliver a higher concentration of anticancer agent into a tumor-feeding artery than intravenous systemic chemotherapy. However, distribution of anticancer agent into several branches of the external carotid artery (ECA) in IAC has not demonstrated sufficient treatment efficacy. To improve the effectiveness of IAC, the flow distribution of anticancer agent into the branches of the ECA in several IAC methods was investigated using computational fluid dynamics (CFD)...
May 15, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28503792/synthetic-cannabinoid-use-in-an-acute-psychiatric-inpatient-unit
#20
Richard Vincent Clancy, Robert Charles Hodgson, Arvind Kendurkar, Margarett Ann Terry, Lawrence Dadd, Donna Maria Clancy, Karen Ryan, Maria Hatzistylis, Benjamin Graham Tinman
In the present study, we explored the prevalence of new psychoactive substance use by people admitted into an Australian acute public mental health facility specializing in comorbid mental health and substance use. These substances have since been banned from retail outlets, but the pattern of uptake and reasons people use them is informative in terms of motivations and the management of substance use more generally. A cross-sectional study to explore the use of synthetic cannabis by people admitted to an acute adult mental health unit was undertaken...
May 15, 2017: International Journal of Mental Health Nursing
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