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Mandibulectomy

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https://www.readbyqxmd.com/read/29434993/prediction-of-decannulation-oral-intake-recovery-overall-survival-and-lung-metastasis-following-oral-malignant-tumor-resection-and-reconstruction
#1
Hidenori Suzuki, Ikuo Hyodo, Yasuhisa Hasegawa
The present study investigated whether tongue base and mandibular bone defects were associated with the rate of decannulation and oral intake recovery, and survival time, including overall and lung metastasis-free survival time, in patients that underwent oral malignant tumor (OMT) resection with reconstruction. A total of 105 patients that underwent OMT resection with laryngeal preservation and reconstruction were recruited. The extent of defects was classified according to Urken's classification. The rates of decannulation and oral intake recovery were assessed with the Kaplan-Meier method...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29433862/three-dimensionally-printed-bioactive-ceramic-scaffold-osseoconduction-across-critical-sized-mandibular-defects
#2
Christopher D Lopez, J Rodrigo Diaz-Siso, Lukasz Witek, Jonathan M Bekisz, Bruce N Cronstein, Andrea Torroni, Roberto L Flores, Eduardo D Rodriguez, Paulo G Coelho
BACKGROUND: Vascularized bone tissue transfer, commonly used to reconstruct large mandibular defects, is challenged by long operative times, extended hospital stay, donor-site morbidity, and resulting health care. 3D-printed osseoconductive tissue-engineered scaffolds may provide an alternative solution for reconstruction of significant mandibular defects. This pilot study presents a novel 3D-printed bioactive ceramic scaffold with osseoconductive properties to treat segmental mandibular defects in a rabbit model...
March 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29428867/raman-spectroscopy-for-assessment-of-bone-resection-margins-in-mandibulectomy-for-oral-cavity-squamous-cell-carcinoma
#3
Elisa M Barroso, Ivo Ten Hove, Tom C Bakker Schut, Hetty Mast, Cornelia G F van Lanschot, Roeland W H Smits, Peter J Caspers, Rob Verdijk, Vincent Noordhoek Hegt, Robert J Baatenburg de Jong, Eppo B Wolvius, Gerwin J Puppels, Senada Koljenović
OBJECTIVES: The aim of this study was to investigate the potential of Raman spectroscopy for detection of oral cavity squamous cell carcinoma (OCSCC) in bone resection surfaces during mandibulectomy. MATERIALS & METHODS: Raman mapping experiments were performed on fresh mandible resection specimens from patients treated with mandibulectomy for OCSCC. A tumour detection algorithm was created based on water concentration and the high-wavenumber range (2800 cm-1-3050 cm-1) of the Raman spectra...
February 8, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29349354/awake-intubation-in-a-patient-with-huge-orocutaneous-fistula-a-case-report
#4
Hye-Jin Kim, So-Hyun Kim, Tae-Heung Kim, Ji-Young Yoon, Cheul-Hong Kim, Eun-Jung Kim
Mask ventilation, the first step in airway management, is a rescue technique when endotracheal intubation fails. Therefore, ordinary airway management for the induction of general anesthesia cannot be conducted in the situation of difficult mask ventilation (DMV). Here, we report a case of awake intubation in a patient with a huge orocutaneous fistula. A 58-year-old woman was scheduled to undergo a wide excision, reconstruction with a reconstruction plate, and supraomohyoid neck dissection on the left side and an anterolateral thigh flap due to a huge orocutaneous fistula that occurred after a previous mandibulectomy and flap surgery...
December 2017: Journal of Dental Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29279825/ct-evaluation-of-underlying-bone-sclerosis-in-patients-with-oral-squamous-cell-carcinoma-a-preliminary-retrospective-study
#5
Gyu-Dong Jo, Won-Jin Yi, Min-Suk Heo, Sam-Sun Lee, Soon-Chul Choi, Kyung-Hoe Huh
Purpose: Underlying bone sclerosis is frequently observed in clinical settings when oral squamous cell carcinoma (OSCC) invades the jaw bone. The aim of this study was to assess the prevalence and characteristics of underlying bone sclerosis in patients with OSCC. Materials and Methods: We retrospectively reviewed the computed tomographic (CT) images of 131 patients who underwent mandibulectomy between January 2012 and December 2015 to treat OSCC. The presence, degree, and extent of underlying bone sclerosis were assessed on CT images and correlated with the following imaging patterns of bone invasion: cortical invasion, medullary invasion with a smooth margin, and medullary invasion with an irregular margin...
December 2017: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/29229291/primary-intraosseous-squamous-cell-carcinoma-of-the-mandible-locoregional-control-and-survival-is-significantly-reduced-if-the-tumour-is-more-than-4cm-in-size
#6
Q Shen, Y Chen, S Gokavarapu, W Cao, T Ji
To establish the prognostic factors for primary intraosseous squamous cell carcinoma we designed a retrospective study of patients treated in the head and neck department of a tertiary referral centre in China from 2010-2015. We collected clinical, radiological, and histopathological data from 36 patients treated during the given time period, among which 34 were followed up. There were 22 male and 12 female patients, 13 of whom gave a history of smoking tobacco and four who drank alcohol. All 34 patients were treated by segmental mandibulectomy and neck dissection...
December 8, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29227794/does-different-mandibulectomy-marginal-vs-segmental-affect-the-prognosis-in-patients-with-oral-squamous-cell-carcinoma
#7
Yu Qiu, Lisong Lin, Bin Shi, Xiaofeng Zhu
PURPOSE: It is unclear whether different mandibular surgical methods affect the prognosis of patients with oral squamous cell carcinoma (OSCC). Accordingly, the authors retrospectively compared the prognosis of patients who underwent marginal mandibulectomy (MG) or segmental mandibulectomy (SG) for OSCC and aimed to determine the factors influencing prognosis. MATERIALS AND METHODS: The authors conducted a retrospective cohort study of 82 patients with OSCC who underwent mandibulectomy at their hospital from January 2001 through January 2015...
November 21, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29183323/cervical-metastasis-of-gingival-carcinoma-misdiagnosed-as-branchiogenic-carcinoma-a-rare-entity-report-of-a-case-and-review-of-literature
#8
Qingjia Sun, Mingxing Chen, Yuxin Sun, Xi Chen, Hongjun Xu, Lingjun Rong, Qiong Wu, Dongdong Zhu
BACKGROUND: A cervical cystic mass is associated with a number of pathologies that present with similar symptoms. These conditions are difficult to differentiate using fine-needle aspiration (FNA), ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI). Another dilemma in the differential diagnosis of cervical cystic masses is due to the controversies associated with the existence of branchiogenic carcinoma (BC). BC is an extremely rare disease that must be differentiated from other conditions presenting with cervical cystic masses, especially cystic metastasis from occult primary lesions...
November 28, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/29178981/translating-computer-aided-design-and-surgical-planning-into-successful-mandibular-reconstruction-using-a-vascularized-iliac-crest-flap
#9
Lei Zheng, Xiaoming Lv, Jie Zhang, Shuming Liu, Jianguo Zhang, Yi Zhang
PURPOSE: This study evaluated the computer-aided approach to the reconstruction of mandibular defects using a vascularized iliac-crest flap. MATERIALS AND METHODS: From December 2015 to October 2016, 14 patients (8 men and 6 women) 18 to 64 years old (median age, 29 yr) were treated at the Peking University School and Stomatology Hospital (Beijing, China). Biopsy specimens from all patients were subjected to histologic examination before segmental mandibulectomy...
November 3, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29165823/identification-of-predisposing-factors-for-osteonecrosis-of-the-jaw-after-marginal-mandibulectomy-in-the-surgical-management-of-oral-squamous-cell-carcinoma
#10
Ran Ito, Jung-Ju Huang, Wei-Chuan Hsieh, Huang-Kai Kao, William Wei-Kai Lao, Ku-Hao Fang, Yenlin Huang, Yu-Liang Chang, Ming-Huei Cheng, Kai-Ping Chang
BACKGROUND: The aim of this study is to evaluate osteonecrosis of the jaw (ONJ) with the extent of marginal mandibulectomy. METHODS: Between January 2006 and December 2012, 3087 patients undergoing ablative resection were consecutively enrolled. Among them, 345 cases undergoing marginal mandibulectomy were retrospectively reviewed. RESULTS: The occurrence of ONJ was 5.51% and associated with body mass index, overall stage, diabetes, concomitant mandibulotomy, and radiotherapy (P = 0...
November 22, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29135994/perioperative-risk-factors-for-postoperative-pneumonia-after-major-oral-cancer-surgery-a-retrospective-analysis-of-331-cases
#11
Jieyun Xu, Jing Hu, Pei Yu, Weiwang Wang, Xingxue Hu, Jinsong Hou, Silian Fang, Xiqiang Liu
OBJECTIVE: Postoperative pneumonia (POP) is common and results in prolonged hospital stays, higher costs, increased morbidity and mortality. However, data on the incidence and risk factors of POP after oral and maxillofacial surgery are rare. This study aims to identify perioperative risk factors for POP after major oral cancer (OC) surgery. METHODS: Perioperative data and patient records of 331 consecutive subjects were analyzed in the period of April 2014 to March 2016...
2017: PloS One
https://www.readbyqxmd.com/read/29114352/bone-allograft-an-option-for-total-mandibular-reconstruction
#12
Masoud Fallahi Motlagh, Mohamad Bayat, Siamak Naji
Total mandibular reconstruction is one of the most challenging modalities in maxillofacial surgery. In this article, we try to introduce a method of total mandible reconstruction. We report a 25-year-old male patient with complete involvement of the mandible by Langerhans cell tumor. The patient underwent total mandibulectomy and reconstruction with bone allograft harvested from a donor who had died the day before. The patient has good functional and aesthetic results in a long time. It seems that bone allograft can be a good alternative to other methods in total mandibular reconstruction...
December 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/29066386/use-of-cable-guide-while-performing-segmental-mandibulectomy-using-gigli-saw
#13
A Rai, M M Khan, A Jain
Segmental mandibulectomies has been performed most commonly in patients having benign or malignant pathologies of mandible. Gigli saw is used for performing segmental mandibulectomy. The two main challenging tasks in the use of Gigli saw includes passage of the device around the bone which is to be cut and the preservation of the underlying soft tissue from getting damaged by the saw during movement. Hence, we propose the use of a "Cable guide with hook" which helps in easy passage of Gigli saw around mandible...
October 21, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29051537/microarray-gene-expression-of-periosteum-in-spontaneous-bone-regeneration-of-mandibular-segmental-defects
#14
Zheyi Li, Juli Pan, Jinling Ma, Zhen Zhang, Yuxing Bai
Spontaneous bone regeneration could occur to reestablish mandibular bony continuity in patients who underwent partial or total mandibulectomy for tumors with periosteum-preserving. However, scarce data is available related to the precise role of periosteum in this bone regeneration. Therefore we aimed to investigate the gene expression of periosteum that were involved in the mandibular bone regeneration. Mandibular segmental defects were created in six mini-pigs with periosteum preserved. The periosteum of defects and control site were harvested at 1 and 2 weeks...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29038629/patient-s-self-assessment-of-social-approval-after-mandibulectomy-with-disarticulation-the-necessity-for-jaw-reconstruction-following-loss-of-facial-symmetry-in-a-resource-poor-african-setting
#15
Bayo Aluko-Olokun, Ademola A Olaitan
OBJECTIVE: Mandibulectomy with disarticulation is usually carried out without reconstruction in Low-Income-Countries. Lower standards of living are usually acceptable and adapted to, in poor societies. This study compares patient's self-assessment of social approval among reconstructed and non-reconstructed cases of mandibulectomy with disarticulation in a resource-poor African setting. MATERIAL AND METHOD: This questionnaire-based study documented patient's self-assessment of social approval of themselves following mandibulectomy with disarticulation...
December 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28969965/axial-four-dimensional-computed-tomographic-images-to-analyze-crosswise-differences-in-protrusive-condylar-movement-in-patients-who-underwent-mandibulectomy-and-free-flap-reconstruction
#16
Masaya Akashi, Toshinori Sekitani, Yumi Ohtsuki, Yasumasa Kakei, Junya Kusumoto, Takumi Hasegawa, Michinori Maeda, Noriyuki Negi, Kazunobu Hashikawa, Yasuyuki Shibuya, Satoru Takahashi, Takahide Komori
OBJECTIVE: Few studies evaluate condylar movement following mandibular reconstruction. The main objective of this study was to show that axial four-dimensional computed tomography (4DCT) could visualize bilateral protrusive condylar movement directly. We used axial 4DCT images to assess condylar protrusion in patients who underwent mandibular reconstruction. METHODS: We enrolled seven healthy volunteers (median age 30 years, range 27-38 years) and seven patients (median age 65 years, range 52-80 years), who underwent mandibulectomy (segmental in five, hemi in one, marginal in one) and free flap reconstruction (using the fibula in six and the radial forearm in one)...
September 1, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28967393/treatment-of-a-mandibular-discontinuity-defect-by-using-a-fibula-free-flap-and-an-implant-supported-fixed-complete-denture-fabricated-with-a-pekk-framework-a-clinical-report
#17
Kyung Chul Oh, Ji-Hyun Park, Joon-Hee Lee, Hong Seok Moon
This clinical report describes the rehabilitation of a patient with a history of mandibulectomy that involved the use of a fibula free flap and an implant-supported fixed complete denture. A recently introduced material, polyetherketoneketone, was used as the framework material for the prosthesis, and the treatment produced favorable esthetic and functional results.
September 27, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28963787/modified-technique-for-preservation-of-inferior-alveolar-nerve-during-mandibulectomy
#18
Min-Jie Chen, Chi Yang, Dong Huang, Dong-Mei He, Yi-Wen Wang, Wen-Hao Zhang
BACKGROUND: The purpose of this article is to introduce the modified technique of preservation of the inferior alveolar nerve (IAN) during mandibulectomy for a benign lesion. METHODS: Five cases of osteofibrous hyperplasia and 3 cases of centricity osteomyelitis were included. During surgery, the IAN was marked using a planned cutting guide. Using an oscillating saw, the depth of the osteotomy along the IAN was controlled until the bone cortex was cut through. After splitting, the bony section was removed, leaving the neurovascular bundle intact...
December 2017: Head & Neck
https://www.readbyqxmd.com/read/28961429/synchronous-reconstruction-of-a-total-mandibulectomy-defect-with-a-single-fibula-osteocutaneous-free-flap
#19
Ramzey Tursun, J Marshall Green, Daniel Winokur, Andre Ledoux
Osteoradionecrosis (ORN) is a well-known and usually late complication of radiation therapy in the treatment of head and neck cancer. Although the therapy can be life extending, it also produces tissue toxicity in ipsilateral and contralateral tissues in an acute and chronic fashion. In the most severe cases of ORN, such as the one presented in this report, bilateral disease results in the need for total mandibulectomy and creates a tremendous reconstructive challenge. The advent of microvascular surgery and free tissue transfer has caused an evolution of the management protocol for severe ORN cases...
January 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28951870/heterogeneity-of-necrotic-changes-between-cortical-and-cancellous-bone-in-mandibular-osteoradionecrosis-a-histopathological-analysis-of-resection-margin-after-segmental-mandibulectomy
#20
Masaya Akashi, Kazunobu Hashikawa, Satoshi Wanifuchi, Junya Kusumoto, Manabu Shigeoka, Shungo Furudoi, Hiroto Terashi, Takahide Komori
BACKGROUND: This study aimed to analyze differences in necrotic changes between cortical and cancellous bone in resection margins after segmental mandibulectomy for advanced mandibular osteoradionecrosis. METHODS: Anteroposterior bone specimens from eleven patients who underwent segmental mandibulectomy with simultaneous free fibula flap reconstruction for advanced osteoradionecrosis were analyzed histopathologically for the presence of necrotic bone based on the presence of blood vessels within Haversian canals...
2017: BioMed Research International
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