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https://www.readbyqxmd.com/read/28817870/re-quality-of-life-in-patients-with-lower-urinary-tract-symptoms-associated-with-bph-change-over-time-in-real-life-practice-according-to-treatment-the-qualiprost-study
#1
https://www.readbyqxmd.com/read/28817823/comparison-of-renal-outcome-among-japanese-patients-with-or-without-microangiopathic-hemolysis-in-malignant-phase-hypertension-a-single-center-retrospective-study
#2
Yoshikuni Nagayama, Yoshihiko Inoue, Kiyoko Inui, Ashio Yoshimura
BACKGROUND/AIMS: Although microangiopathic hemolysis (MAH) is a well-known complication of malignant phase hypertension (MPH), only less data on whether MAH in MPH predicts renal outcome exist. Therefore, we evaluated whether MAH was associated with the renal outcome in patients with MPH. METHODS: We conducted a single-center, retrospective, cohort study. Data from 35 patients diagnosed with MPH between October 1998 and January 2015 were analyzed. MPH was defined as the presence of a diastolic blood pressure of ≥120 mm Hg and grades III/IV hypertensive retinopathy according to the Keith-Wagener-Barker classification...
August 18, 2017: Nephron
https://www.readbyqxmd.com/read/28817811/downregulation-of-microrna-330-correlates-with-the-radiation-sensitivity-and-prognosis-of-patients-with-brain-metastasis-from-lung-cancer
#3
Li-Peng Jiang, Zhi-Tu Zhu, Yue Zhang, Chun-Yan He
BACKGROUND: The present study sought to explore the role of microRNA-330 (miR-330) in predicting the radiation response and prognosis of patients with brain metastasis (BM) from lung cancer (LC). METHODS: Patients with BM from LC were identified and classified into radiation-sensitive and radiation-resistant groups according to the overall survival rate, local and distant recurrence rate after conventional whole-brain radiation therapy. Quantitative realtime polymerase chain reaction (qRT-PCR) was used to detect miR-330 expression in serum...
August 16, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28817765/preventive-effects-of-lamotrigine-in-bipolar-ii-versus-bipolar-i-disorder
#4
Takeshi Terao, Atsuko Ishida, Toshifumi Kimura, Masao Yarita, Terufumi Hara
OBJECTIVE: The preventive effects of mood stabilizers on recurrence/relapse in bipolar disorders have been investigated mostly in bipolar I disorder (BPI) patients, with limited reports on bipolar II disorder (BPII) patients. Here, we conducted an explorative data analysis to investigate whether the preventive effect of lamotrigine on recurrence /relapse in BPII is better than in BPI. METHODS: Data from Japanese patients with a diagnosis of BPI or BPII according to DSM-IV-TR were analyzed in an open-label, noninterventional, naturalistic, prospective postmarketing surveillance study of lamotrigine...
August 15, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28817760/association-between-hypercoagulability-and-severe-obstructive-sleep-apnea
#5
Seung-No Hong, Hee-Chul Yun, Joon Hyuk Yoo, Seung Hoon Lee
Importance: Obstructive sleep apnea (OSA) is related to the increased risk of cardiovascular disease. Although the pathogenesis of this association remains unclear, an alteration in coagulability is suspected as a link. Objective: To investigate the association between the severity of OSA and blood coagulability. Design, Setting, and Participants: A retrospective cohort study conducted at a tertiary care university hospital evaluated 146 patients with OSA from January 1, 2009, to July 31, 2015...
August 17, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28817728/evaluation-of-reference-genes-for-reverse-transcription-quantitative-real-time-pcr-rt-qpcr-studies-in-silene-vulgaris-considering-the-method-of-cdna-preparation
#6
Pavla Koloušková, James D Stone, Helena Štorchová
Accurate gene expression measurements are essential in studies of both crop and wild plants. Reverse transcription quantitative real-time PCR (RT-qPCR) has become a preferred tool for gene expression estimation. A selection of suitable reference genes for the normalization of transcript levels is an essential prerequisite of accurate RT-qPCR results. We evaluated the expression stability of eight candidate reference genes across roots, leaves, flower buds and pollen of Silene vulgaris (bladder campion), a model plant for the study of gynodioecy...
2017: PloS One
https://www.readbyqxmd.com/read/28817725/development-of-a-psychological-intervention-for-fatigue-after-stroke
#7
Simiao Wu, Trudie Chalder, Kirstin E Anderson, David Gillespie, Malcolm R Macleod, Gillian E Mead
BACKGROUND AND AIM: Post-stroke fatigue (PSF) is common and distressing, but there is insufficient evidence to recommend any effective treatment for it. Psychological interventions are effective in treating fatigue in other conditions. This paper describes the development and evaluation of the feasibility of a psychological intervention for PSF. METHODS: Based on psychological correlates of PSF and evidence-based psychological interventions for fatigue in other medical conditions, we developed a manualised psychological intervention for PSF, with input from stroke clinicians, psychological therapists, and stroke survivors...
2017: PloS One
https://www.readbyqxmd.com/read/28817715/longitudinal-sequencing-in-intramuscular-coordination-a-new-hypothesis-of-dynamic-functions-in-the-human-rectus-femoris-muscle
#8
Christoph von Laßberg, Julia A Schneid, Dominik Graf, Felix Finger, Walter Rapp, Norman Stutzig
The punctum fixum-punctum mobile model has been introduced in previous publications. It describes general principles of intersegmental neuromuscular succession patterns to most efficiently generate specific movement intentions. The general hypothesis of this study is that these principles-if they really do indicate a fundamental basis for efficient movement generation-should also be found in intramuscular coordination and should be indicated by "longitudinal sequencing" between fibers according to the principles of the punctum fixum-punctum mobile model...
2017: PloS One
https://www.readbyqxmd.com/read/28817645/translation-cultural-adaptation-and-validation-of-simplified-chinese-version-of-the-anterior-cruciate-ligament-return-to-sport-after-injury-acl-rsi-scale
#9
Tianwu Chen, Peng Zhang, Yunxia Li, Kate Webster, Jian Zhang, Wei Yao, Yue Yin, Chingchong Ai, Shiyi Chen
PURPOSE: To translate and cross-culturally adapt the anterior cruciate ligament-return to sport after injury (ACL-RSI) into simplified Chinese [ACL-RSI (Cn)]. METHOD: In this diagnostic study, the translation, cross-culturally adaptation, and validation of the ACL-RSI was performed according to international guidelines. A total of 112 patients with ACL reconstruction participated in this study. All were capable of competitive sports before the injury and completed the Knee Injury and Osteoarthritis Outcome (KOOS), the International Knee Documentation Committee (IKDC), the Tampa Scale of Kinesiophobia (TSK), and the Tegner activity score...
2017: PloS One
https://www.readbyqxmd.com/read/28817629/maldi-tof-ms-identification-of-anopheles-gambiae-giles-blood-meal-crushed-on-whatman-filter-papers
#10
Sirama Niare, Lionel Almeras, Fatalmoudou Tandina, Amina Yssouf, Affane Bacar, Ali Toilibou, Ogobara Doumbo, Didier Raoult, Philippe Parola
BACKGROUND: Identification of the source of mosquito blood meals is an important component for disease control and surveillance. Recently, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) profiling has emerged as an effective tool for mosquito blood meal identification, using the abdomens of freshly engorged mosquitoes. In the field, mosquito abdomens are crushed on Whatman filter papers to determine the host feeding patterns by identifying the origin of their blood meals...
2017: PloS One
https://www.readbyqxmd.com/read/28817620/gtsp1-expression-in-non-smoker-and-non-drinker-patients-with-squamous-cell-carcinoma-of-the-head-and-neck
#11
Pamela de Oliveira Soares, Patrícia Maluf Cury, Rossana Verónica Mendoza López, Cláudio Roberto Cernea, Erika Erina Fukuyama, David Livingstone Alves Figueiredo, Francisco Gorgonio da Nobrega, Otavio Alberto Curioni, Fabio Daumas Nunes, Raquel Ajub Moyses, Maria Lúcia Bueno Garcia
INTRODUCTION: The main risk factors for head and neck squamous cell carcinoma (HNSCC) are tobacco and alcohol consumption and human papillomavirus (HPV) infection. However, in a subset of patients, no risk factors can be identified. Glutathione S-transferase π (GTSP1) is a carcinogen-detoxifying enzyme that is activated by exposure to carcinogens, and it is associated with a reduction in response to toxic therapies. We studied the expression of GTSP1 in tumor and non-tumor tissue samples from patients with and without these risks to identify whether GTSP1 expression differs according to exposure to carcinogens...
2017: PloS One
https://www.readbyqxmd.com/read/28817600/development-and-evaluation-of-height-diameter-at-breast-models-for-native-chinese-metasequoia
#12
Mu Liu, Zhongke Feng, Zhixiang Zhang, Chenghui Ma, Mingming Wang, Bo-Ling Lian, Renjie Sun, Li Zhang
Accurate tree height and diameter at breast height (dbh) are important input variables for growth and yield models. A total of 5503 Chinese Metasequoia trees were used in this study. We studied 53 fitted models, of which 7 were linear models and 46 were non-linear models. These models were divided into two groups of single models and multivariate models according to the number of independent variables. The results show that the allometry equation of tree height which has diameter at breast height as independent variable can better reflect the change of tree height; in addition the prediction accuracy of the multivariate composite models is higher than that of the single variable models...
2017: PloS One
https://www.readbyqxmd.com/read/28817589/relationship-between-atherosclerosis-and-occlusal-support-of-natural-teeth-with-mediating-effect-of-atheroprotective-nutrients-from-the-sonic-study
#13
Sayaka Tada, Kazunori Ikebe, Kei Kamide, Yasuyuki Gondo, Chisato Inomata, Hajime Takeshita, Ken-Ich Matsuda, Masahiro Kitamura, Shinya Murakami, Mai Kabayama, Ryousuke Oguro, Chikako Nakama, Tatsuo Kawai, Koichi Yamamoto, Ken Sugimoto, Ayumi Shintani, Takuma Ishihara, Yasumichi Arai, Yukie Masui, Ryutaro Takahashi, Hiromi Rakugi, Yoshinobu Maeda
Whereas most of studies investigating relationship between oral health and atherosclerosis have focused on periodontitis, very few of them were examined about occlusal status of natural teeth which possibly influence dietary habit. The primary aim of this cross-sectional study was to investigate the association between the occlusal support of posterior teeth and the prevalence of atherosclerosis in community-dwelling septuagenarians. Also, the second aim was to test the hypothesis that the intake of key nutrients for atherosclerosis prevention would have a mediating effect on the relationship between the occlusal status and atherosclerosis...
2017: PloS One
https://www.readbyqxmd.com/read/28817542/safety-of-transesophageal-echocardiography%C3%A2-guided-electrical-cardioversion-in-patients-with-atrial-fibrillation-and-inadequate-anticoagulation
#14
Joanna Zaprutko, Artur Baszko, Michał Michalak, Karol Kochman, Radosław Szymański, Jan Kłopocki, Anna Nowicka, Rafał Dankowski, Marek Michalski, Piotr Kałmucki, Andrzej Szyszka
INTRODUCTION    Restoring sinus rhythm in patients with atrial fibrillation (AF)/atrial flutter (AFl) requires adequate oral anticoagulation prior to direct current cardioversion (DCC). Some patients eligible for DCC are not properly anticoagulated. OBJECTIVES    The aim of the study was to assess risk factors for thrombus and spontaneous echo contrast (SEC) in the left atrium (LA) as well as the safety profile of transesophageal echocardiography (TEE)-guided DCC in patients with inadequate anticoagulation...
August 9, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28817503/interprovider-communication-using-a-scheduled-provider-alert-response-communication-system-in-3-inpatient-neurology-units
#15
James E Siegler, Dan Finegan, Scott E Kasner, Raymond S Price
BACKGROUND: Nonemergent communications between nursing staff and residents often occur randomly throughout the workday at teaching institutions, resulting in inefficiency and interruptions of scheduled resident educational conferences or periods of overnight rest. OBJECTIVE: The aim of this study was to determine whether a quality improvement communication strategy can reduce interruptive notifications during scheduled resident didactic sessions. METHODS: We conducted a prospective, mixed-methods trial of a communication strategy between nurses and residents in 3 neurology units of an academic institution...
August 16, 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28817457/a-comparison-by-meta-analysis-of-papillary-early-gastric-carcinoma-to-its-tubular-counterpart-for-the-risk-of-lymph-node-metastasis-and-submucosal-invasion
#16
Xiao-Yong Wang, Jin Yan, Jia Wu, Yi-Feng Zhang, Guo-Xin Zhang
BACKGROUND AND AIM: At present, the decision to perform endoscopic resection for treating either papillary early gastric cancer (EGC) or tubular EGC is made according to identical criteria. However, there is controversy in the literature whether the risk of lymph node metastasis (LNM) and submucosal invasion for both disease modalities is equal, and this prompts investigation to clarify this issue. METHODS: The PubMed and Web of Science databases were searched for relevant studies published up to January 2017...
August 16, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28817397/real-world-data-on-paliperidone-palmitate-for-the-treatment-of-schizophrenia-and-other-psychotic-disorders-a-systematic-review-of-randomized-and-nonrandomized-studies
#17
Robin Emsley, Eduard Parellada, Miquel Bioque, Berta Herrera, Teresa Hernando, Marta García-Dorado
The aim of this study was to perform a systematic review of the effects of 1-month paliperidone palmitate (PP1M) for the treatment of schizophrenia and related psychotic disorders in terms of outcomes reported in real-world evidence studies. A systematic review of real-world randomized and nonrandomized studies with PP1M was performed and is reported according to PRISMA guidelines. Comparative effectiveness data with oral antipsychotics indicate that PP1M has a lower likelihood of relapse-related events, including rehospitalization, and these differences are clinically relevant...
August 16, 2017: International Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28817373/cabozantinib-as-salvage-therapy-for-patients-with-tyrosine-kinase-inhibitor-refractory-differentiated-thyroid-cancer-results-of-a-multicenter-phase-ii-international-thyroid-oncology-group-trial
#18
Maria E Cabanillas, Jonas A de Souza, Susan Geyer, Lori J Wirth, Michael E Menefee, Stephen V Liu, Komal Shah, John Wright, Manisha H Shah
Purpose Sorafenib and lenvatinib are oral multikinase inhibitors targeting vascular endothelial growth factor receptor (VEGFR) and approved for radioiodine (RAI)-refractory differentiated thyroid cancer (DTC). However, there are no approved second- or third-line therapies. MET is implicated in resistance to VEGFR inhibitors. Cabozantinib is an oral multikinase inhibitor targeting MET in addition to VEGFR and is approved for medullary thyroid cancer. In a phase I study of cabozantinib, five of eight patients with DTC previously treated with a VEGFR-targeted therapy had an objective response to cabozantinib...
August 17, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28817316/filling-quality-of-the-reports-of-adverse-drug-reactions-received-at-the-pharmacovigilance-centre-of-s%C3%A3-o-paulo-brazil-missing-information-hinders-the-analysis-of-suspected-associations
#19
Adalton Ribeiro, Silvana Lima, Maria-Elisa Zampieri, Mirtes Peinado, Albert Figueras
Background The completeness and accuracy of the reports of suspected adverse drug reactions is important in pharmacovigilance. The aim of the present study was to analyze the quality of the information included in the reports sent to the Pharmacovigilance Centre of São Paulo (Brazil). Research Design and Methods A sample of 999 reports received from January 2013 to December 2014 was selected. The quality of the filled information was evaluated according to a 'sufficiency' criterion to apply the Karch-Lasagna causality algorithm...
August 17, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28817217/mind-the-cell-seasonal-variation-in-telomere-length-mirrors-changes-in-leukocyte-profile
#20
Michaël Beaulieu, Laure Benoit, Steven Abaga, Peter M Kappeler, Marie J E Charpentier
Leukocytes are typically considered as a whole in studies examining telomere dynamics in mammals. Such an approach may be precarious, as leukocytes represent the only nucleated blood cells in mammals, their composition varies temporally, and telomere length differs between leukocyte types. To highlight this limitation, we examined here whether seasonal variation in leukocyte composition was related to variation in telomere length in free-ranging mandrills (Mandrilllus sphinx). We found that the leukocyte profile of mandrills varied seasonally, with lower lymphocyte proportion being observed during the long dry season presumably because of the combined effects of high nematode infection and stress at that time of the year...
August 17, 2017: Molecular Ecology
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