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Optic disc

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https://www.readbyqxmd.com/read/29332249/correlation-of-flow-density-as-measured-using-optical-coherence-tomography-angiography-with-structural-and-functional-parameters-in-glaucoma-patients
#1
Maged Alnawaiseh, Larissa Lahme, Viktoria Müller, André Rosentreter, Nicole Eter
PURPOSE: To evaluate the correlation between flow density, as measured by optical coherence tomography angiography (OCTA), and structural and functional parameters in patients with open-angle glaucoma. METHODS: Thirty-four eyes of 34 patients with open-angle glaucoma and 35 eyes of 35 healthy subjects were prospectively included in this study. OCTA was performed using RTVue XR Avanti with AngioVue. The macula was imaged with a 3 × 3 mm scan and the optic nerve head (ONH) with a 4...
January 13, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29332119/autofluorescence-of-skin-advanced-glycation-end-products-as-a-risk-factor-for-open-angle-glaucoma-the-alienor-study
#2
Cedric Schweitzer, Audrey Cougnard-Gregoire, Vincent Rigalleau, Jean-Francois Dartigues, Florence Malet, Marie-Benedicte Rougier, Marie-Noelle Delyfer, Catherine Helmer, Jean-Francois Korobelnik, Cecile Delcourt
Purpose: To analyze the association between skin autofluorescence (sAF), estimating tissue accumulation of advanced glycation end-products (AGEs), and open angle glaucoma (OAG) in an elderly population. Methods: The Antioxydants, Lipides Essentiels, Nutrition and maladies OculaiRes (ALIENOR) study is an on-going epidemiologic population-based study on age-related eye diseases. In 2009 to 2010, 624 subjects, aged 74 years or older, were recruited. All subjects underwent a complete eye examination, including optic disc color photography and spectral-domain optical coherence tomography (SD-OCT) examination...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29331255/an-automated-and-robust-image-processing-algorithm-for-glaucoma-diagnosis-from-fundus-images-using-novel-blood-vessel-tracking-and-bend-point-detection
#3
Soorya M, Ashish Issac, Malay Kishore Dutta
Glaucoma is an ocular disease which can cause irreversible blindness. The disease is currently identified using specialized equipment operated by optometrists manually. The proposed work aims to provide an efficient imaging solution which can help in automating the process of Glaucoma diagnosis using computer vision techniques from digital fundus images. The proposed method segments the optic disc using a geometrical feature based strategic framework which improves the detection accuracy and makes the algorithm invariant to illumination and noise...
February 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29330062/fundus-densitometry-findings-suggest-optic-disc-hemorrhages-in-primary-open-angle-glaucoma-have-an-arterial-origin
#4
Jonathan C Chou, Clara C Cousins, John B Miller, Brian J Song, Lucy Q Shen, Michael A Kass, Janey L Wiggs, Louis R Pasquale
PURPOSE: To analyze optic disc hemorrhages (DH) associated with primary open-angle glaucoma by quantifying their geometric profile and comparing their densitometry with hemorrhages from retinal vein occlusions (RVO) and retinal macroaneurysms (MA), which have venous and arterial sources of bleeding, respectively. DESIGN: Retrospective cross-sectional study METHODS: Setting: Massachusetts Eye & Ear POPULATION: Fundus images of DH (n=40), MA (n=14), and RVO (n=25) were identified...
January 9, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29329139/diagnostic-ability-and-structure-function-relationship-of-peripapillary-optical-microangiography-measurements-in-glaucoma
#5
Harsha L Rao, Srilakshmi Dasari, Mohammed Riyazuddin, Narendra K Puttaiah, Zia S Pradhan, Robert N Weinreb, Kaweh Mansouri, Carroll A B Webers
PURPOSE: To evaluate the diagnostic abilities of peripapillary optical microangiography (OMAG) measurements in eyes with primary open angle glaucoma (POAG) and to evaluate the relationship of these measurements with retinal nerve fiber layer (RNFL) thickness and visual sensitivities in different peripapillary sectors. METHODS: In a cross-sectional study, 97 eyes of 57 control subjects and 101 eyes of 66 POAG patients underwent OMAG and RNFL imaging with optical coherence tomography...
January 11, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29328088/determination-of-the-optimum-double-pass-image-through-focus-operators
#6
Anibal G de Paul, Roberto F Sanchez, Luis A Issolio
A set of autofocus operators (AFO) are assessed for their ability to determine the optimal double-pass image as well as their potential to detect the focus lines and the disc of least confusion in astigmatic eyes. Eight AFO and three optical quality parameters (OQP) often used to analyze double-pass aerial images were considered. To quantify the discriminative power of each AFO and OQP, a maximum discrimination (MD) parameter was proposed. Double-pass images were obtained from an artificial eye with an induced astigmatism (Cylinder: -1  D, -0...
January 1, 2018: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29327060/optical-coherence-tomography-analysis-of-the-optic-nerve-head-and-surrounding-structures-in-long-duration-international-space-station-astronauts
#7
Nimesh Patel, Anastas Pass, Sara Mason, Charles R Gibson, Christian Otto
Importance: After long-duration spaceflight, morphological changes in the optic nerve head (ONH) and surrounding tissues have been reported. Objective: To develop methods to quantify ONH and surrounding tissue changes using preflight and postflight optical coherence tomographic scans of the ONH region. Design, Setting, and Participants: Two separate analyses were done on retrospective data, with the first comparing a preflight group with a control group, followed by preflight to postflight analysis...
January 11, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29321433/a-case-of-cv2-crmp5-antibody-related-paraneoplastic-optic-neuropathy-associated-with-small-cell-lung-cancer
#8
Masanori Nakajima, Ayumi Uchibori, Yuki Ogawa, Tai Miyazaki, Yaeko Ichikawa, Kimihiko Kaneko, Toshiyuki Takahashi, Ichiro Nakashima, Hirokazu Shiraishi, Masakatsu Motomura, Atsuro Chiba
A 61-year-old woman who had smoked for 40 years developed subacute dizziness, ataxic gait, opsoclonus, and right visual impairment. She had right optic disc swelling and optic nerve gadolinium enhancement on magnetic resonance imaging. She had small-cell lung cancer (SCLC), with CV2/collapsin response mediator protein (CRMP) 5 and HuD antibodies in her serum and cerebrospinal fluid. She was diagnosed with paraneoplastic optic neuropathy (PON) accompanied by paraneoplastic opsoclonus-ataxia syndrome. Her symptoms improved after removing the SCLC...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29317760/shape-dependent-physical-mutilation-and-lethal-effects-of-silver-nanoparticles-on-bacteria
#9
Debashish Acharya, K Malabika Singha, Piyush Pandey, Bidhan Mohanta, Jina Rajkumari, L Paikhomba Singha
In this report, spherical silver nanoparticle (AgNP-sp) and rod-shaped silver nanoparticle (AgNR) were prepared by chemical reduction method and their antibacterial activity against various Gram-positive and Gram-negative bacteria had been evaluated for their efficiency. Minimal inhibitory concentration (MIC) tests were conducted to study the antibacterial properties, and substantiated with killing kinetics of silver nanoparticles (AgNPs). The study revealed that both AgNP-sp and AgNRs are good antibacterial candidates...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29315318/correlative-light-and-immuno-electron-microscopy-of-retinal-tissue-cryostat-sections
#10
Thomas Burgoyne, Amelia Lane, William E Laughlin, Michael E Cheetham, Clare E Futter
Correlative light-electron microscopy (CLEM) is a powerful technique allowing localisation of specific macromolecules within fluorescence microscopy (FM) images to be mapped onto corresponding high-resolution electron microscopy (EM) images. Existing methods are applicable to limited sample types and are technically challenging. Here we describe novel methods to perform CLEM and immuno-electron microscopy (iEM) on cryostat sections utilising the popular FM embedding solution, optimal cutting temperature (OCT) compound...
2018: PloS One
https://www.readbyqxmd.com/read/29306778/influence-on-proliferation-and-adhesion-of-human-gingival-fibroblasts-from-different-titanium-surface-decontamination-treatments-an-in-vitro-study
#11
Cao Jie, Tong Wang, Pu Yinfei, Tang Zhihui, Meng Huanxin
OBJECTIVES: To investigate the effects of different decontamination treatments on microstructure of titanium (Ti) surface as well as proliferation and adhesion of human gingival fibroblasts (HGFs). MATERIAL AND METHODS: Ti discs with machined (M) and sand blasted, acid etched (SAE) surfaces were treated with five different decontamination treatments: (1) stainless steel curette (SSC), ultrasonic system with (2) straight carbon fiber tip (UCF) or (3) metal tip (UM), (4) rotating Ti brush (RTB), and (5) Er:YAG laser (30 mJ/pulse at 30 Hz)...
December 24, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29305731/association-of-bruch-s-membrane-opening-and-optic-disc-morphology-to-axial-length-and-visual-field-defects-in-eyes-with-primary-open-angle-glaucoma
#12
Hideo Nakanishi, Kenji Suda, Munemitsu Yoshikawa, Tadamichi Akagi, Takanori Kameda, Hanako Ohashi Ikeda, Satoshi Yokota, Yasuo Kurimoto, Akitaka Tsujikawa
PURPOSE: To examine the morphology of Bruch's membrane opening (BMO), optic disc, and peripapillary atrophy (PPA) by scanning laser ophthalmoscopy (SLO) and spectral-domain optical coherence tomography (SD-OCT), and to determine their association with the axial length and visual field defects. METHODS: This was a cross-sectional study of 94 eyes of 56 subjects; 77 eyes were diagnosed with primary open-angle glaucoma and 17 eyes as normal. The margins of the optic disc were determined in the SLO images, and that of the BMO in the SD-OCT images...
January 5, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29305369/radius-maumenee-syndrome-a-rare-cause-of-glaucoma
#13
Sara Homem de Melo Marques, Cláudia Farinha, Amélia Martins, Pedro Faria
Case presentation of a 41-year-old woman with long-standing bilateral eye injection whose clinical findings included bilateral episcleral vessel engorgement and tortuosity, raised intraocular pressure with open iridocorneal angles and left optic disc cupping. All remaining objective examination was normal. She underwent cranial and orbits CT and CT-angiography scans which were unremarkable. Optical coherence tomography of the peripapillary nerve fibre layer and automated perimetry were compatible with advanced glaucomatous damage on the left eye...
January 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29304267/double-optic-disc-pit-with-glial-plugs-imaged-by-wide-field-optical-coherence-tomography
#14
Ismini Koulouri, Eric D Gaier, Dean Eliott, Demetrios G Vavvas
A rare case of a woman in her thirties with double optic disc pits involving opposing sectors is reported. Significantly decreased vision due to macular schisis was noted. Wide-field optical coherence tomography revealed distinct laminar defects and glial tufts associated with each pit. This case illustrates a rare view into the pathogenesis of optic disc pits. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:52-54.].
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29303881/association-between-optic-disc-hemorrhage-and-renal-function-in-south-korea
#15
Jae Yeun Lee, Joon Mo Kim, SeongHee Shim, Jin Young Lee, Chungkwon Yoo, Ji Yoon Song, Yu Sam Won, Young Youl Hyun, Ki Ho Park
PURPOSE: To investigate the relationship between renal function and disc hemorrhage (DH). METHODS: This retrospective cross-sectional survey was conducted at Kangbuk Samsung Hospital Health Screening Center between August 2012 and July 2013, and a total of 168,044 participants at least 20 years of age who voluntarily visited the health screening center for systemic and ophthalmologic examinations, including fundus photography, were enrolled. All subjects underwent a physical examination and provided samples for laboratory analysis...
January 4, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29303456/bobble-head-doll-syndrome-report-of-2-cases-and-a-review-of-the-literature-with-video-documentation-of-the-clinical-phenomenon
#16
Bryan Renne, Stefan Rueckriegel, Sudheesh Ramachandran, Julia Radic, Paul Steinbok, Ash Singhal
Bobble-head doll syndrome (BHDS) is a rare pediatric movement disorder presenting with involuntary 2- to 3-Hz head movements. Common signs and symptoms also found on presentation include macrocephaly, ataxia, developmental delay, optic disc pallor or atrophy, hyperreflexia, tremor, obesity, endocrinopathy, visual disturbance or impairment, headache, and vomiting, among others. The syndrome is associated with suprasellar cysts, third ventricular cysts, or aqueductal obstruction, along with a few other less common conditions...
January 5, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29303150/cigarette-smoking-and-glaucoma-in-the-united-states-population
#17
S M Law, X Lu, F Yu, V Tseng, S K Law, A L Coleman
PurposeTo evaluate the association between cigarette smoking and glaucoma in the United States population.Patients and methodsUS civilian, non-institutionalized population from 2005 to 2008 administrations of the National Health and Nutrition Examination Survey that were ≥40 years of age with visual fields and optic disc photographs were included. Diagnosis of glaucoma was based on the Rotterdam criteria. Logistic regression modeling was performed to assess the association between glaucoma and smoking history, while controlling for age, gender, ethnicity, household income, alcohol consumption, diabetes, and hypertension...
January 5, 2018: Eye
https://www.readbyqxmd.com/read/29303140/optic-disc-coloboma-in-two-nigerian-siblings-case-report-and-review-of-literature
#18
Y O Babalola, O O Olawoye, P O Idam
We report two cases of bilateral asymmetric optic disc coloboma (ODC) in siblings. The index patient is a 9-year-old Nigerian girl with severe cognitive deficit who presented with a poor vision of 3 years' duration. She had a history of childhood febrile convulsions and delayed developmental milestones. Her visual acuity could not be assessed because she had a cognitive deficit and expressive aphasia. Ocular examination revealed a very large excavated right optic disc with only a strip of remnant neuro-retinal rim superiorly, and a smaller left optic disc with inferior disc excavation, superior wedge of the pink neuro-retinal rim as well as a temporal optic disc pit...
November 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29298687/segmentation-error-in-spectral-domain-optical-coherence-tomography-measures-of-the-retinal-nerve-fibre-layer-thickness-in-idiopathic-intracranial-hypertension
#19
Anuriti Aojula, Susan P Mollan, John Horsburgh, Andreas Yiangou, Kiera A Markey, James L Mitchell, William J Scotton, Pearse A Keane, Alexandra J Sinclair
BACKGROUND: Optical Coherence Tomography (OCT) imaging is being increasingly used in clinical practice for the monitoring of papilloedema. The aim is to characterise the extent and location of the Retinal Nerve Fibre Layer (RNFL) Thickness automated segmentation error (SegE) by manual refinement, in a cohort of Idiopathic Intracranial Hypertension (IIH) patients with papilloedema and compare this to controls. METHODS: Baseline Spectral Domain OCT (SDOCT) scans from patients with IIH, and controls with no retinal or optic nerve pathology, were examined...
January 4, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29297794/the-eye-of-the-azara-s-agouti-dasyprocta-azarae-morphological-observations-and-selected-ophthalmic-diagnostic-tests
#20
André Tavares-Somma, Nathália Seabra, Bret A Moore, Mario Sato, Rogério R Lange, Fabiano Montiani-Ferreira
The purpose of this study was to carry out a descriptive investigation of the Azara's agouti ( Dasyprocta azarae) eye and to establish reference values of select ophthalmic diagnostic tests and physiologic parameters. A total of 19 healthy agoutis were used. Select ophthalmic diagnostic tests were performed, including Schirmer tear test type I (STTI), analysis of the conjunctival bacterial microflora, corneal esthesiometry, and tonometry. B-mode ultrasonic biometry, fundus photography, optical coherence tomography, and gross and histologic analysis of two eyes were also performed...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
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