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https://www.readbyqxmd.com/read/28710187/utility-of-microscope-integrated-optical-coherence-tomography-mioct-in-the-treatment-of-myopic-macular-hole-retinal-detachment
#1
Atul Kumar, Prateek Kakkar, Raghav Dinesh Ravani, Ashish Markan
Macular hole-associated retinal detachment in high myopia is described as a final stage in progression of myopic traction maculopathy (MTM).(1â€"3) Shimada et al(4) described the progressive stages of MTM from macular retinoschisis to serous retinal detachment in high myopia. Stage 4 MTM is characterised as disappearance of retinoschisis with progression to retinal detachment due to macular hole formation. It is hypothesised that vitreoschisis and abnormal vitreo-retinal interface create the premacular tangential traction...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28704046/creating-a-more-perennial-problem-mountaintop-removal-coal-mining-enhances-and-sustains-saline-baseflows-of-appalachian-watersheds
#2
Fabian Nippgen, Matthew R V Ross, Emily S Bernhardt, Brian L McGlynn
Mountaintop removal coal mining (MTM) is a form of surface mining where ridges and mountain tops are removed with explosives to access underlying coal seams. The crushed rock material is subsequently deposited in headwater valley fills (VF). We examined how this added water storage potential affects streamflow using a paired watershed approach consisting of two sets of mined and unmined watersheds in West Virginia. The mined watersheds exported 7-11% more water than the reference watersheds, primarily due to higher and more sustained baseflows...
July 13, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28687533/mobile-health-technology-using-a-wearable-sensorband-for-female-college-students-with-problem-drinking-an-acceptability-and-feasibility-study
#3
Noelle Regina Leonard, Michelle Silverman, Dawa Phuti Sherpa, Madeline A Naegle, Hyorim Kim, Donna L Coffman, Marcy Ferdschneider
BACKGROUND: An increasing number of mobile app interventions have been developed for problem drinking among college students; however, few studies have examined the integration of a mobile app with continuous physiological monitoring and alerting of affective states related to drinking behaviors. OBJECTIVE: The aim of this paper was to evaluate the acceptability and feasibility of Mind the Moment (MtM), a theoretically based intervention for female college students with problem drinking that combines brief, in-person counseling with ecological momentary intervention (EMI) on a mobile app integrated with a wearable sensorband...
July 7, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28686709/axial-length-changes-in-highly-myopic-eyes-and-influence-of-myopic-macular-complications-in-japanese-adults
#4
Hideharu Ohsugi, Yasushi Ikuno, Tomohiro Shoujou, Kanako Oshima, Eiko Ohsugi, Hitoshi Tabuchi
PURPOSE: To investigate changes of the axial length in normal eyes and highly myopic eyes and influence of myopic macular complications in Japanese adults. STUDY DESIGN: Retrospective longitudinal case series. METHODS: The changes in the axial length of 316 eyes from 316 patients (mean age, 63.8 ± 9.0 years; range, 34-82; 240 females) examined using IOLMaster with a follow-up period of at least 1 year were studied. This study included 85 non-highly myopic eyes (|refractive error| ≤ 5 diopters; 63 females; non-highly myopic group), 165 highly myopic eyes (refractive error ≤ -6 diopters or axial length ≥ 26 mm; 124 females) without macular complications (no complications group), 32 eyes (25 females) with myopic traction maculopathy (MTM group), and 34 eyes (28 females) with myopic choroidal neovascularization (CNV group)...
2017: PloS One
https://www.readbyqxmd.com/read/28666816/application-of-the-consolidated-framework-for-implementation-research-to-community-pharmacy-a-framework-for-implementation-research-on-pharmacy-services
#5
Sarah J Shoemaker, Geoffrey M Curran, Holly Swan, Benjamin S Teeter, Jeremy Thomas
BACKGROUND: Community pharmacies are an increasingly important health care setting with opportunities for improving quality and safety, yet little is understood about determinants of implementation in this setting. OBJECTIVE: This paper presents an implementation framework for pharmacy based on the Consolidated Framework for Implementation Research (CFIR). METHODS: This study employed a critical review of 45 articles on professional services provided in community pharmacies, including medication therapy management (MTM), immunizations, and rapid HIV testing...
June 2, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28645553/a-mixed-methods-evaluation-of-an-integrated-medication-management-program-and-implications-for-implementation
#6
Shira H Fischer, Courtney K Armstrong, Erin L Duffy, Peter S Hussey
BACKGROUND: Improving medication adherence is a common and challenging issue. Taking medications as prescribed becomes particularly difficult for individuals with multiple chronic conditions. Poor adherence can lead to exacerbated health issues and prolonged disease severity. Medication Therapy Management is increasingly being used to help clinics improve medication adherence and reduce adverse events, but factors that enable implementation of such programs are not well identified. OBJECTIVE: To describe the factors associated with implementation of an innovative pharmacy program and to measure the impact of the intervention...
June 10, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28609102/mesoporous-titania-microspheres-with-highly-tunable-pores-as-an-anode-material-for-lithium-ion-batteries
#7
Michael G Fischer, Xiao Hua, Bodo D Wilts, Ilja Gunkel, Thomas M Bennett, Ullrich Steiner
Mesoporous titania microspheres (MTMs) have been employed in many applications, including (photo)catalysis as well as energy conversion and storage. Their morphology offers a hierarchical structural design motif that lends itself to being incorporated into established large-scale fabrication processes. Despite the fact that device performance hinges on the precise morphological characteristics of these materials, control over the detailed mesopore structure and the tunability of the pore size remains a challenge...
July 12, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28596967/prdx6-upregulation-by-curcumin-attenuates-ischemic-oxidative-damage-via-sp1-in-rats-after-stroke
#8
Gongwei Jia, Botao Tan, Jingxi Ma, Lina Zhang, Xinhao Jin, Changqing Li
BACKGROUND: The role of Peroxiredoxin 6 (Prdx6) in brain ischemia remains unclear. Curcumin (Cur) treatment elicits neuroprotective effects against cerebral ischemic injury, and the associated mechanisms may involve Prdx6. In this study, we investigated whether Prdx6 and the transcription factor specific protein 1 (SP1) were involved in the antioxidant effect of Cur after stoke. METHODS: Focal cerebral ischemic injury was induced by transient middle cerebral artery occlusion for 2 hours in male Sprague-Dawley rats treated with or without Prdx6 siRNA...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28573464/imaging-features-of-mammary-type-myofibroblastoma-of-soft-tissue-a-case-series-with-literature-review
#9
Gokhan Kuyumcu, Brian P Rubin, Carl Winalski
Mammary-type myofibroblastoma (MTM) is a rare, benign neoplasm that is histologically identical to myofibroblastoma of the breast, but occurring in an extramammary site. The masses have been reported in superficial and deep soft tissue sites and visceral locations with the inguinal area and lower extremities are the most common. Most previous reports of MTMs have concentrated on clinical and pathological findings, with very limited information regarding imaging characteristics. Here, we describe three cases of MTM diagnosed at our institution, with a focus on imaging findings...
September 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28549592/economic-outcomes-of-pharmacist-physician-medication-therapy-management-for-polypharmacy-elderly-a-prospective-randomized-controlled-trial
#10
Hsiang-Wen Lin, Chih-Hsueh Lin, Chin-Kai Chang, Che-Yi Chou, I-Wen Yu, Cheng-Chieh Lin, Tsai-Chung Li, Chia-Ing Li, Yow-Wen Hsieh
BACKGROUND/PURPOSE: With an increasing geriatric population, the need for effective management of chronic conditions and medication use in the elderly is growing. Medication use in the elderly presents significant challenges due to changes in pharmacodynamic and pharmacokinetic profiles. We aimed to examine the impact of a collaborative physician-pharmacist medication therapy management (MTM) program for polypharmacy elderly patients. METHODS: Elderly patients with multiple chronic conditions on polypharmacy were enrolled in this prospective, randomized, and controlled study over 16 months of implementation...
May 23, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28535785/optimizing-medication-appropriateness-in-older-adults-a-randomized-clinical-interventional-trial-to-decrease-anticholinergic-burden
#11
Daniela C Moga, Erin L Abner, Dorinda N Rigsby, Lynne Eckmann, Mark Huffmyer, Richard R Murphy, Beth B Coy, Gregory A Jicha
BACKGROUND: The complexity of medication therapy in older adults with multiple comorbidities often leads to inappropriate prescribing. Drugs with anticholinergic properties are of particular interest because many are not recognized for this property; their use may lead to increased anticholinergic burden resulting in significant health risks, as well as negatively impacting cognition. Medication therapy management (MTM) interventions showed promise in addressing inappropriate medication use, but the effectiveness of targeted multidisciplinary team interventions addressing anticholinergic medications in older populations is yet to be determined...
May 23, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28530799/bioinspired-interface-engineering-for-moisture-resistance-in-nacre-mimetic-cellulose-nanofibrils-clay-nanocomposites
#12
Kun Yao, Shu Huang, Hu Tang, Yeping Xu, Gerd Buntkowsky, Lars A Berglund, Qi Zhou
The interfacial adhesion design between "mortar" and "bricks" is essential for mechanical and barrier performance of nanocellulose-based nacre-mimetic nanocomposites, especially at high moisture conditions. To address this fundamental challenge, dopamine (DA) has been conjugated to cellulose nanofibrils (CNFs) and subsequently assembled with montmorillonite (MTM) to generate layered nanocomposite films inspired by the strong adhesion of mussel adhesive proteins to inorganic surfaces under water. The selective formation of catechol/metal ion chelation and hydrogen bonding at the interface between MTM platelets and CNFs bearing DA renders transparent films with strong mechanical properties, particularly at high humidity and in wet state...
May 31, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28490836/prior-knowledge-of-target-direction-and-intended-movement-selection-improves-indirect-reaching-movement-decoding
#13
Hongbao Li, Yaoyao Hao, Shaomin Zhang, Yiwen Wang, Weidong Chen, Xiaoxiang Zheng
Objective. Previous studies have demonstrated that target direction information presented by the dorsal premotor cortex (PMd) during movement planning could be incorporated into neural decoder for achieving better decoding performance. It is still unknown whether the neural decoder combined with only target direction could work in more complex tasks where obstacles impeded direct reaching paths. Methods. In this study, spike activities were collected from the PMd of two monkeys when performing a delayed obstacle-avoidance task...
2017: Behavioural Neurology
https://www.readbyqxmd.com/read/28483010/pharmacist-managed-diabetes-center-interventions-ensure-quality-and-safety-in-elderly-patients
#14
Geoffrey Twigg, John Motsko, Jennifer Thomas, Tosin David
OBJECTIVES: This quality-improvement study aimed to replicate historical Patient Safety Clinical Pharmacy Services Collaborative results in high-risk Medicare beneficiaries with diabetes to achieve reductions in A1C, adverse drug events (ADEs), and potential ADEs (pADEs). DESIGN: The model included an interdisciplinary team led by a pharmacist located inside a community pharmacy to provide disease state management and medication therapy management (MTM) to the study population...
May 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28479354/lyophilization-cycle-design-for-dual-chamber-cartridges-and-a-method-for-online-process-control-the-dcc-lyomate-procedure
#15
Christoph Korpus, Wolfgang Friess
Freeze-drying process design is a challenging task that necessitates a profound understanding of the complex interrelation among critical process parameters (e.g., shelf temperature and chamber pressure), heat transfer characteristics of the involved materials (e.g., product containers and holder devices), and critical quality attributes of the product (e.g., collapse temperatures). The Dual Chamber Cartridge "(DCC) LyoMate" (from lyophilization and automated) is a manometric temperature measurement-based process control strategy that was developed within this study to streamline this complicated task...
August 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28448783/effectiveness-of-a-clinical-pharmacist-medication-therapy-management-program-in-discontinuation-of-drugs-to-avoid-in-the-elderly
#16
Nicole Caffiero, Thomas Delate, Mercy D Ehizuelen, Kris Vogel
BACKGROUND: Despite evidence of fall risk associated with some drugs to avoid in the elderly (DAEs), many aged patients continue to receive them. OBJECTIVE: To assess the effectiveness of a clinical pharmacist medication therapy management program (MTM) on discontinuation of prescribed DAEs. METHODS: This was a retrospective cohort study conducted at an integrated health care delivery system. Kaiser Permanente Colorado beneficiaries aged ≥65 years who were MTM-eligible and targeted for a DAE dispensing between 01/01/2015 and 09/30/2015 were included in the observation group...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28448777/effect-of-an-advanced-pharmacy-practice-experience-on-medication-therapy-management-services-in-a-centralized-retail-pharmacy-program
#17
Joseph P Vande Griend, Melissa Rodgers, Wesley Nuffer
BACKGROUND: Medication therapy management (MTM) delivery is increasingly important in managed care. Successful delivery positively affects patient health and improves Centers for Medicare & Medicaid Services star ratings, a measure of health plan quality. As MTM services continue to grow, there is an increased need for efficient and effective care models. The primary objectives of this project were to describe the delivery of MTM services by fourth-year Advanced Pharmacy Practice Experience (APPE) students in a centralized retail pharmacy system and to evaluate and quantify the clinical and financial contributions of the students...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28420595/using-an-array-of-implementation-strategies-to-improve-success-rates-of-pharmacist-initiated-medication-therapy-management-services-in-community-pharmacies
#18
Rachel Stafford, Jeremy Thomas, Nalin Payakachat, Tiffany Diemer, Michele Lang, Brooke Kordsmeier, Geoffrey Curran
BACKGROUND: With the introduction of the Centers for Medicare and Medicaid Services Stars Measure program has come a greater expectation of Medication Therapy Management (MTM) services from community pharmacies. To meet the growing demand of these services, pharmacies have sought out various methods of engaging pharmacists to provide MTM. Barriers for completing MTM include inadequate time to complete the services, insufficient staffing, lack of sufficient compensation, billing difficulty, lack of interest among patients (including refusing MTM services when offered), inadequate training/experience, and lack of support from management...
April 8, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28413165/applying-multi-theory-model-mtm-of-health-behavior-change-to-predict-water-consumption-instead-of-sugar-sweetened-beverages
#19
Manoj Sharma, Hannah Priest Catalano, Vinayak K Nahar, Vimala C Lingam, Paul Johnson, M Allison Ford
BACKGROUND: A substantial proportion of college students to not drink enough water and consume sugar-sweetened beverages (SSBs). Consumption of SSBs is associated with weight gain, obesity, type 2 diabetes mellitus, dental carries, and increased risk for cardiovascular disease. Hence, the purpose of this study was to use the multi-theory model (MTM) in predicting initiation and sustenance of plain water consumption instead of sugar-sweetened beverages among college students. STUDY DESIGN: A cross-sectional study...
February 25, 2017: Journal of Research in Health Sciences
https://www.readbyqxmd.com/read/28381896/establishment-and-implementation-of-a-required-medication-therapy-management-advanced-pharmacy-practice-experience
#20
Wesley Nuffer, Eric Gilliam, Megan Thompson, Joseph Vande Griend
Objective. To develop a community pharmacy-based medication therapy management (MTM) advanced pharmacy practice experience (APPE) that provides students with skills and knowledge to deliver entry-level pharmacy MTM services. Design. The University of Colorado Skaggs School of Pharmacy & Pharmaceutical Sciences (SSPPS) partnered with three community pharmacy chains to establish this three-week, required MTM APPE. Students completed the American Pharmacists Association MTM Certificate Course prior to entering the APPE...
March 25, 2017: American Journal of Pharmaceutical Education
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