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Spectral domain optical coherence tomography

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https://www.readbyqxmd.com/read/28937877/changes-in-peripapillary-nerve-fiber-layer-thickness-after-adjuvant-stereotactic-radiotherapy-in-patients-with-neovascular-age-related-macular-degeneration
#1
Mahdy Ranjbar, Maximilian Kurz, Annekatrin Holzhey, Dirk Rades, Salvatore Grisanti
PURPOSE: To evaluate the effect of stereotactic radiotherapy (SRT) in conjunction with intravitreal injections (IVI) of anti-vascular endothelial growth factor (anti-VEGF) drugs on peripapillary retinal nerve fiber layer (pRNFL) thickness in patients with neovascular age-related macular degeneration (nAMD). METHODS: This was a retrospective, observational case series of patients with nAMD, who underwent SRT and subsequently had at least 12 months of complete follow-up...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937859/choroidal-thickness-in-traumatic-optic-neuropathy
#2
Ju-Yeun Lee, Doo-Ri Eo, Kyung-Ah Park, Sei Yeul Oh
PURPOSE: To examine the choroidal thickness in patients with indirect traumatic optic neuropathy (TON) Methods: Patients with unilateral traumatic optic neuropathy over a period of 4 years were included in this study. Horizontal and vertical enhanced-depth imaging (EDI) from spectral-domain optical coherence tomography (SD-OCT) scans of the fovea were obtained in patients with unilateral TON within 2 weeks of injury. The main outcome measure was the choroidal thickness at nine locations...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937828/the-effects-of-systemic-alfuzosin-and-tamsulosin-hydrochloride-on-choroidal-thickness-and-pupil-diameter-sizes-in-cases-with-benign-prostatic-hyperplasia
#3
Mustafa Dogan, Bunyamin Kutluksaman, Ibrahim Keles, Mustafa Karalar, Ahmet Omer Halat
PURPOSE: To compare the effects of alfuzosin hydrochloride and tamsulosin hydrochloride on choroidal thickness (CT) and pupil diameter (PD) sizes in patients with benign prostatic hyperplasia. SUBJECTS AND METHODS: Sixty-three men patients with newly diagnosis of benign prostatic hyperplasia were randomly assigned to either alfuzosin hydrochloride or to tamsulosin hydrochloride groups in this prospective, randomized, parallel-group clinical trial. Enhanced depth imaging spectral-domain optical coherence tomography, pupillography were obtained at baseline, 1st and 3rd month, and choroidal thicknesses and pupil diameter sizes were compared between the two groups...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28937528/long-term-follow-up-of-patients-with-choroideremia-with-scleral-pits-and-tunnels-as-a-novel-observation
#4
Sanne M van Schuppen, Mays Talib, Arthur A Bergen, Jacoline B Ten Brink, Ralph J Florijn, Camiel J F Boon, Mary J van Schooneveld
PURPOSE: To evaluate the long-term clinical course and visual outcome of patients with choroideremia. METHODS: Clinical examination, a social questionnaire, and medical records review of 21 patients with choroideremia from 14 families. RESULTS: The mean follow-up time was 25.2 years (SD: 13.3; range 2-57 years). The mean age at symptom onset was 15.1 years (SD: 10.1; range 5-40 years). Best-corrected visual acuity was stable until the age of 35 (P = 0...
September 20, 2017: Retina
https://www.readbyqxmd.com/read/28937146/associations-of-aniseikonia-with-metamorphopsia-and-retinal-displacements-after-epiretinal-membrane-surgery
#5
Y Ichikawa, Y Imamura, M Ishida
PurposeTo determine the correlation of the degree of aniseikonia with the retinal displacements and metamorphopsia in patients that have undergone successful epiretinal membrane (ERM) surgery.MethodsSubjects were 28 eyes with an ERM in 28 patients. The New Aniseikonia Test (NAT) and M-CHARTS were used to quantify the degree of preoperative and postoperative aniseikonia and metamorphopsia. We also evaluated the distance between the intersections of 2 sets of retinal vessels situated vertically or horizontally by using spectral-domain optical coherence tomography (SD-OCT) images in 28 patients...
September 22, 2017: Eye
https://www.readbyqxmd.com/read/28935399/optical-coherence-tomography-biomarkers-as-functional-outcome-predictors-in-diabetic-macular-edema-treated-with-dexamethasone-implant
#6
Dinah Zur, Matias Iglicki, Catharina Busch, Alessandro Invernizzi, Miriana Mariussi, Anat Loewenstein
PURPOSE: Identification and characterization of patients with diabetic macular edema (DME) are important for individualizing treatment and optimizing outcome. We investigated optical coherence tomography (OCT) biomarkers for DME treated by intravitreal dexamethasone (DEX) implant. DESIGN: Multicenter, retrospective, observational cohort study. PARTICIPANTS: A total of 299 eyes from 284 patients treated with DEX implant for DME (naïve, n = 209; refractory, n = 90)...
September 18, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28933972/visual-acuity-and-macular-and-peripapillary-thickness-in-high-myopia
#7
Solmaz Abdolrahimzadeh, Francesco Parisi, Andrea Maria Plateroti, Federica Evangelista, Vito Fenicia, Gianluca Scuderi, Santi Maria Recupero
PURPOSE: To investigate best corrected visual acuity (BCVA), and choroidal and retinal thickness values between high myopes without myopic maculopathy and emmetropes. MATERIALS AND METHODS: Case control study where 53 myopes with axial length (AL) above 26 mm without myopic maculopathy and 53 age-matched emmetropes with AL between 21.50 and 24.50 were included as controls. Complete ophthalmological examination and biometry were performed. Choroidal and individual retinal layer thickness maps using spectral domain optical coherence tomography were obtained in the macular and peripapillary area with enhanced depth imaging...
September 21, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28933233/optical-coherence-tomography-angiography-retinal-vascular-network-assessment-in-multiple-sclerosis
#8
Roberta Lanzillo, Gilda Cennamo, Chiara Criscuolo, Antonio Carotenuto, Nunzio Velotti, Federica Sparnelli, Alessandra Cianflone, Marcello Moccia, Vincenzo Brescia Morra
BACKGROUND: Optical coherence tomography (OCT) angiography is a new method to assess the density of the vascular networks. Vascular abnormalities are considered involved in multiple sclerosis (MS) pathology. OBJECTIVE: To assess the presence of vascular abnormalities in MS and to evaluate their correlation to disease features. METHODS: A total of 50 MS patients with and without history of optic neuritis (ON) and 46 healthy subjects were included...
September 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28930882/reproducibility-of-bruch-s-membrane-opening-minimum-rim-width-measurements-with-spectral-domain-optical-coherence-tomography
#9
Keunheung Park, Jinmi Kim, Jiwoong Lee
PURPOSE: To evaluate the reproducibility of Bruch's membrane opening-minimum rim width (BMO-MRW) measurements obtained with Spectralis optical coherence tomography (OCT) in normal and glaucoma subjects. METHODS: In total, 123 eyes from 123 subjects (65 healthy, 58 glaucoma subjects) were included. BMO-MRW measurements were repeated three times during the same visit using Spectralis OCT. The BMO points and internal limiting membrane were identified with automated software and corrected manually when necessary...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28926646/vascular-hypoperfusion-in-acute-optic-neuritis-is-a-potentially-new-neurovascular-model-for-demyelinating-diseases
#10
Ta-Ching Chen, Chao-Yuan Yeh, Chao-Wen Lin, Chung-May Yang, Chang-Hao Yang, I-Hung Lin, Pao-Yang Chen, Jung-Yu Cheng, Fung-Rong Hu
PURPOSE: Optic neuritis is highly correlated with multiple sclerosis and is a major cause of acute visual loss and long-term neuronal degeneration. Primary cerebral hypoperfusion has been reported in brain demyelinating diseases. This study investigated whether peripapillary perfusion is changed in patients with acute optic neuritis (AON). METHODS: This three-year cohort study was conducted from September 1 2012, to August 31, 2015. Two hundred and forty-one patients with non-glaucomatous acute optic neuropathy were screened, and 42 non-highly myopic patients who had suffered their first episode of unilaterally idiopathic AON were studied...
2017: PloS One
https://www.readbyqxmd.com/read/28926210/clinical-relevance-of-retinal-structure-in-children-with-laser-treated-retinopathy-of-prematurity-versus-controls-using-optical-coherence-tomography
#11
Florina Stoica, Adela Chirita-Emandi, Nicoleta Andreescu, Alina Stanciu, Cristian G Zimbru, Maria Puiu
PURPOSE: We aimed to assess the macular anatomy using spectral domain optical coherence tomography (SD-OCT), in children born preterm who had laser-treated retinopathy of prematurity (ROP), and to investigate the relationship between structural changes in macula and visual function. METHODS: Thirty-seven 3-8 years old children were included in the study in two groups: 20 children born preterm [(<34 weeks of gestation, birthweight (BW) <2000 g)] who had laser-treated ROP in the Neonatology Department, Municipal Clinical Emergency Hospital of Timisoara, Romania; and 17 controls (children born at term, without eye disease, matched for age and gender)...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28924434/ruptured-retinal-arterial-macroaneurysm-secondary-to-toxoplasmic-kyrieleis-arteriolitis-a-case-report
#12
Natalie Huang, W Andrew Lee, Sean Rivera, Sandra R Montezuma
PURPOSE: The aim of this report was to describe multimodal ocular imaging findings in a patient who presented with a ruptured retinal arterial macroaneurysm (RAM) associated with toxoplasmic Kyrieleis arteriolitis. METHODS: We report the case of a 64-year-old man with a history of systemic hypertension and dense amblyopia of the left eye who presented with decreased vision and new floaters in the left eye. Color fundus photography, spectral-domain optical coherence tomography, fluorescein angiography, and indocyanine green angiography were used as diagnostic imaging tools...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28924418/optical-coherence-tomography-findings-and-successful-repair-of-retina-detachment-in-knobloch-syndrome
#13
Nazanin Ebrahimiadib, Bobeck S Modjtahedi, Kevin Ferenchak, Thanos D Papakostas, Jason S Mantagos, Demetrios G Vavvas
A 7-year-old Afghani girl was referred to the retina clinic of Massachusetts Eye and Ear for a chronic-appearing, macula-off retinal detachment in the left eye. On examination, best-corrected visual acuity was 20/400 in the right eye and 20/800 in the left eye. She had bilateral horizontal nystagmus. Ophthalmoscopy revealed prominent choroidal vessels, chorioretinal atrophy in the macular area, attenuated retinal vasculature, and pale optic discs bilaterally. Spectral domain optical coherence tomography demonstrated atrophy of the choriocapillaris and the retinal pigment epithelium, retinal thinning, and abnormal foveal contour...
2017: Digital Journal of Ophthalmology: DJO
https://www.readbyqxmd.com/read/28924415/stalagmite-like-preretinal-inflammatory-deposits-in-vitrectomized-eyes-with-posterior-uveitis
#14
Yoshihiro Yonekawa, Ashkan M Abbey, Lily van Laere, Ankoor R Shah, Benjamin J Thomas, Alan J Ruby, Lisa J Faia
We report a new clinical sign of vitreous inflammation in patients with posterior uveitis: spectral-domain optical coherence tomography identified stalagmite-like, discrete, diffusely distributed, hyperreflective, preretinal deposits in previously vitrectomized eyes of 2 patients during flares of posterior uveitis. The extent of the deposits correlated with disease activity. The underlying primary diseases encountered were necrotizing retinochoroiditis secondary to toxoplasmosis and primary central nervous system lymphoma...
2017: Digital Journal of Ophthalmology: DJO
https://www.readbyqxmd.com/read/28922378/relationships-of-orientation-discrimination-threshold-and-visual-acuity-with-macular-lesions-in-age-related-macular-degeneration
#15
Haojie Fu, Bin Zhang, Jianliang Tong, Harold Bedell, Hecheng Zhang, Yating Yang, Chaochao Nie, Yingdong Luo, Xiaoling Liu
PURPOSE: To measure visual acuity and metamorphopsia in patients with age-related macular degeneration (AMD) and to explore their relationship with macular lesions. METHODS: In this cross-sectional study, a total of 32 normal subjects (32 eyes) and 35 AMD patients (35 eyes) were recruited. They were categorized into 4 groups: normal, dry AMD, non-active wet AMD, and active wet AMD. Best-corrected visual acuity (BCVA) was measured using the Early Treatment Diabetic Retinopathy Study protocol...
2017: PloS One
https://www.readbyqxmd.com/read/28922330/lamina-cribrosa-thickness-in-patients-with-keratoconus
#16
Serkan Akkaya, Bekir Küçük
PURPOSE: To evaluate the thickness and depth of lamina cribrosa (LC) in the optic nerve head region of the eyes in patients with nonglaucomatous keratoconus and to compare the thickness and depth with those of age-matched controls. METHODS: This was a cross-sectional, observational study comprising 45 patients with keratoconus and 56 healthy subjects. Analysis of LC imaging was performed using spectral domain optical coherence tomography. Data collected included spherical equivalent, central corneal thickness, axial length, intraocular pressure, and keratometry...
September 14, 2017: Cornea
https://www.readbyqxmd.com/read/28922031/optic-nerve-head-characteristics-in-chronic-angle-closure-glaucoma-detected-by-swept-source-oct
#17
Dejiao Li, Taibo Li, Eleftherios I Paschalis, Haobing Wang, Elise V Taniguchi, Zi-Ning Choo, Marissa K Shoji, Scott H Greenstein, Stacey C Brauner, Angela V Turalba, Louis R Pasquale, Lucy Q Shen
PURPOSE: To compare structural features in prelaminar and laminar tissues of the optic nerve head (ONH) in chronic angle closure glaucoma (CACG), primary open angle glaucoma (POAG), and control subjects. MATERIALS AND METHODS: ONH imaging was performed using swept-source optical coherence tomography (SS-OCT) for measurements of minimum rim width at Bruch's membrane opening (BMO-MRW), horizontal, and vertical lamina cribrosa depth (LCD). Prelaminar defects, categorized as hole and wedge, and lamina cribrosa (LC) defects were identified...
September 18, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28920886/retinal-layer-segmentation-in-multiple-sclerosis-a-systematic-review-and-meta-analysis
#18
Axel Petzold, Laura J Balcer, Peter A Calabresi, Fiona Costello, Teresa C Frohman, Elliot M Frohman, Elena H Martinez-Lapiscina, Ari J Green, Randy Kardon, Olivier Outteryck, Friedemann Paul, Sven Schippling, Patrik Vermersch, Pablo Villoslada, Lisanne J Balk
BACKGROUND: Structural retinal imaging biomarkers are important for early recognition and monitoring of inflammation and neurodegeneration in multiple sclerosis. With the introduction of spectral domain optical coherence tomography (SD-OCT), supervised automated segmentation of individual retinal layers is possible. We aimed to investigate which retinal layers show atrophy associated with neurodegeneration in multiple sclerosis when measured with SD-OCT. METHODS: In this systematic review and meta-analysis, we searched for studies in which SD-OCT was used to look at the retina in people with multiple sclerosis with or without optic neuritis in PubMed, Web of Science, and Google Scholar between Nov 22, 1991, and April 19, 2016...
October 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28919773/sickle-cell-retinopathy-improving-care-with-a-multidisciplinary-approach
#19
REVIEW
Farid Menaa, Barkat Ali Khan, Bushra Uzair, Abder Menaa
Sickle cell retinopathy (SCR) is the most representative ophthalmologic complication of sickle cell disease (SCD), a hemoglobinopathy affecting both adults and children. SCR presents a wide spectrum of manifestations and may even lead to irreversible vision loss if not properly diagnosed and treated at the earliest. Over the past decade, multidisciplinary research developments have focused upon systemic, genetic, and ocular risk factors of SCR, enabling the clinician to better diagnose and manage these patients...
2017: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/28919660/collaborative-sdoct-segmentation-and-analysis-software
#20
Yeyi Yun, Aaron Carass, Andrew Lang, Jerry L Prince, Bhavna J Antony
Spectral domain optical coherence tomography (SDOCT) is routinely used in the management and diagnosis of a variety of ocular diseases. This imaging modality also finds widespread use in research, where quantitative measurements obtained from the images are used to track disease progression. In recent years, the number of available scanners and imaging protocols grown and there is a distinct absence of a unified tool that is capable of visualizing, segmenting, and analyzing the data. This is especially noteworthy in longitudinal studies, where data from older scanners and/or protocols may need to be analyzed...
February 2017: Proceedings of SPIE
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