keyword
MENU ▼
Read by QxMD icon Read
search

Retinal nerve fiber layer

keyword
https://www.readbyqxmd.com/read/28650925/quantitative-analysis-of-the-inner-retinal-layer-thicknesses-in-age-related-macular-degeneration-using-corrected-optical-coherence-tomography-segmentation
#1
Ilkay Kilic Muftuoglu, Hema L Ramkumar, Dirk-Uwe Bartsch, Amit Meshi, Raouf Gaber, William R Freeman
PURPOSE: To characterize inner retinal damage in patients with dry age-related macular degeneration (AMD) using high-resolution spectral domain optical coherence tomography images. METHODS: Sixty eyes of 60 patients with AMD were categorized using the Age-Related Eye Disease Study (AREDS) severity scale. Spectral domain optical coherence tomography images of these patients were quantified by manually correcting the segmentation of each retinal layer, including the retinal nerve fiber layer, ganglion cell layer, and inner plexiform layer to ensure accurate delineation of layers...
June 23, 2017: Retina
https://www.readbyqxmd.com/read/28647203/gene-therapy-for-leber-hereditary-optic-neuropathy-low-and-medium-dose-visual-results
#2
John Guy, William J Feuer, Janet L Davis, Vittorio Porciatti, Phillip J Gonzalez, Rajeshwari D Koilkonda, Huijun Yuan, William W Hauswirth, Byron L Lam
PURPOSE: To determine the effects of AAV2(Y444,500,730F)-P1ND4v2 in patients with Leber hereditary optic neuropathy (LHON). DESIGN: Prospective open-label, unilateral single-dose, intravitreal injection of AAV2(Y444,500,730F)-P1ND4v2 per participant. PARTICIPANTS: Fourteen patients with visual loss and mutated G11778A mitochondrial DNA. METHODS: Intravitreal injection with the gene therapy vector AAV2(Y444,500,730F)-P1ND4v2 into 1 eye...
June 21, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28644852/comparisons-of-retinal-vessel-diameter-and-glaucomatous-parameters-between-both-eyes-of-subjects-with-clinically-unilateral-pseudoexfoliation-syndrome
#3
Yasuyuki Takai, Masaki Tanito, Tetsuro Omura, Ryo Kawasaki, Yumiko Kawasaki, Akihiro Ohira
PURPOSE: Pseudoexfoliation syndrome (PEX), the most common identifiable cause of open-angle glaucoma, might affect the retinal hemodynamics. To test this, we compared retinal vessel diameter and glaucoma-related parameters between eyes with pseudoexfoliation material (PE+) and fellow unaffected (PE-) eyes of patients with clinically unilateral PEX. METHODS: The medical records of 30 consecutive Japanese subjects were reviewed retrospectively. The retinal vessel diameters were measured and expressed as the central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) using standardized software...
2017: PloS One
https://www.readbyqxmd.com/read/28643042/oct-in-alzheimer-s-disease-thinning-of-the-rnfl-and-superior-hemiretina
#4
João Paulo Cunha, Rita Proença, Arnaldo Dias-Santos, Rita Almeida, Helena Águas, Marta Alves, Ana Luísa Papoila, Carlota Louro, António Castanheira-Dinis
BACKGROUND: Peripapillary retinal nerve fiber layer (pRNFL) and internal macular layer thinning have been demonstrated in Alzheimer's disease (AD) with optical coherence tomography (OCT) studies. The purpose of this study is to compare the pRNFL thickness and overall retinal thickness (RT) in AD patients with non-AD patients, using spectral domain optical coherence tomography (SD-OCT) and determine the sectors most characteristically affected in AD. METHODS: A cross-sectional study was performed to determine the pRNFL and overall macular RT thicknesses in AD and non-AD patients, attending a tertiary hospital center...
June 22, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28641680/ophthalmological-evaluation-of-integrated-resistance-and-aerobic-training-during-70-day-bed-rest
#5
Giovanni Taibbi, Ronita L Cromwell, Susana B Zanello, Patrice O Yarbough, Robert J Ploutz-Snyder, Bernard F Godley, Gianmarco Vizzeri
INTRODUCTION: We evaluated ophthalmic changes in healthy individuals who underwent integrated resistance and aerobic training (iRAT) during 70-d 6° head-down tilt (HDT) bed rest (BR). METHODS: Participants were selected using NASA standard screening procedures. Standardized NASA BR conditions were implemented. Subjects were randomly assigned to the iRAT protocol or no exercise during HDTBR. Weekly ophthalmic examinations were performed in the sitting (pre/post-BR only) and HDT (BR only) positions...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28636408/pattern-visual-evoked-potential-pattern-electroretinogram-and-retinal-nerve-fiber-layer-thickness-in-patients-with-migraine-during-and-after-aura
#6
Amany Abd El-Fattah El-Shazly, Yousra Ahmed Farweez, Momen Mahmoud Hamdi, Noha Ezzat El-Sherbiny
PURPOSE: To study pattern visual evoked potential (PVEP), pattern electroretinogram (PERG), and retinal nerve fiber layer (RNFL) thickness in patients with migraine during and after aura. MATERIALS AND METHODS: We included 60 eyes of 60 patients with migraine (Group 1) and 30 healthy volunteers (30 eyes) as controls (Group 2). Group 1 was studied twice, during a visual aura (1-a) and in between attacks (1-b). All participants underwent full ophthalmological examination, PVEP, PERG, and optical coherence tomographyOCT imaging of the RNFL thickness for each patient...
June 21, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28635102/ratiometric-analysis-of-optical-coherence-tomography-measured-in%C3%A2-vivo-retinal-layer-thicknesses-for-the-detection-of-early-diabetic-retinopathy
#7
Basanta Bhaduri, Ryan L Shelton, Ryan M Nolan, Lucas Hendren, Alexandra Almasov, Leanne T Labriola, Stephen A Boppart
Influence of diabetes mellitus (DM) and diabetic retinopathy (DR) on parafoveal retinal thicknesses and their ratios was evaluated. Six retinal layer boundaries were segmented from spectral-domain optical coherence tomography images using open-source software. Five study groups: (1) healthy control (HC) subjects, and subjects with (2) controlled DM, (3) uncontrolled DM, (4) controlled DR and (5) uncontrolled DR, were identified. The one-way analyses of variance (ANOVA) between adjacent study groups (i. e...
June 21, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28632411/the-effect-of-dexamethasone-intravitreal-implant-on-retinal-nerve-fiber-layer-in-patients-diagnosed-with-branch-retinal-vein-occlusion
#8
Orhan Ayar, Atilla Alpay, Yaran Koban, Mehmet Orcun Akdemir, Serpil Yazgan, Sılay Canturk Ugurbas, Suat Hayri Ugurbas
PURPOSE: To evaluate the effect of a single dose of intravitreal dexamethasone (DEX) implant on retinal nerve fiber layer (RNFL) thickness in patients with branch retinal vein occlusion (BRVO) in a 6-month period. MATERIALS AND METHODS: This retrospective observational study included the patients with BRVO who received intravitreal DEX implant and whose assessment included the baseline RNFL thickness measurements. The data of 26 eyes of 24 patients were retrospectively analyzed...
June 20, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28632028/the-effect-of-combined-systemic-erythropoietin-and-steroid-on-non-arteritic-anterior-ischemic-optic-neuropathy-a-prospective-study
#9
Mohammad Pakravan, Hamed Esfandiari, Kiana Hassanpour, Sarvnaz Razavi, Parastou Pakravan
BACKGROUND: To investigate the effect of combined intravenous (IV) erythropoietin (EPO) and corticosteroid as well as systemic steroid alone for the treatment of non-arteritic anterior ischemic optic neuropathy (NAION). METHODS: In this prospective interventional comparative case series, 113 consecutive patients diagnosed with recent onset (less than 14 days) NAION were included. Patients were categorized into three groups. 40 patients received systemic IV corticosteroid combined with recombinant human erythropoietin (rhEPO) (group 1), 43 patients received systemic corticosteroid alone (group 2), and 30 patients were enrolled as the control group (group 3)...
February 26, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28631244/optical-coherence-tomography-angiography-in-pre-perimetric-open-angle-glaucoma
#10
Gilda Cennamo, Daniela Montorio, Nunzio Velotti, Federica Sparnelli, Michele Reibaldi, Giovanni Cennamo
PURPOSE: To evaluate the diagnostic efficacy of optical coherence tomography (OCT) angiography, in patients with pre-perimetric open-angle glaucoma. METHODS: Thirty-eight consecutive eyes of 26 patients with pre-perimetric open-angle glaucoma and 48 normal eyes of 32 controls were included in this prospective study. We evaluated OCT angiography, spectral-domain OCT and visual fields parameters. Differences between controls and patients and between OCT angiography parameters and traditional glaucoma measurements were evaluated...
June 19, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28630788/evaluation-of-ganglion-cell-inner-plexiform-layer-thickness-after-vitreoretinal-surgery-with-internal-limiting-membrane-peeling-in-cases-with-idiopathic-macular-hole
#11
Sibel Demirel, Ahmed Abdullayev, Özge Yanık, Figen Batıoğlu, Emin Özmert
OBJECTIVES: To evaluate macular retinal ganglion cell-inner plexiform layer (GCIPL) thickness after vitrectomy with internal limiting membrane (ILM) peeling for idiopathic macular holes using spectral domain optical coherence tomography (SD-OCT). MATERIALS AND METHODS: Eighteen eyes of 18 patients with unilateral idiopathic macular hole who underwent vitrectomy with ILM peeling were retrospectively analyzed. Healthy fellow eyes of the patients and 18 eyes of 18 age-matched healthy individuals constituted the control group...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28628662/quantitative-analysis-of-retinal-layers-on-three-dimensional-spectral-domain-optical-coherence-tomography-for-pituitary-adenoma
#12
Min Sun, Zhiqiang Zhang, Chiyuan Ma, Suihua Chen, Xinjian Chen
PURPOSE: To quantitatively investigate the characteristics of eyes with pituitary adenoma presented by three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) using three common indices, including thickness, optical intensity ratio, and optical intensity attenuation coefficient (OIAC). METHODS: The SD-OCT database of 38 patients with pituitary adenoma and 39 normal controls were included in the study. Quadrantal and average measurements of thickness, optical intensity ratio, and OIAC were calculated for macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL) combined with inner plexiform layer (IPL) (GCIPL) and/or the collective ganglion cell complex (GCC)...
2017: PloS One
https://www.readbyqxmd.com/read/28626779/optical-coherence-tomography-and-visual-evoked-potentials-in-pediatric-ms
#13
Amy T Waldman, Grant T Liu, Amy M Lavery, Geraldine Liu, William Gaetz, Tomas S Aleman, Brenda L Banwell
OBJECTIVE: To determine the relative ability of optical coherence tomography (OCT) and pattern-reversal visual evoked potentials (pVEPs) to detect visual pathway involvement in pediatric-onset MS. METHODS: Pediatric-onset MS participants (onset <18 years) and healthy controls (HCs) underwent OCT (Cirrus HD-OCT) and pVEPs. Retinal nerve fiber layer (RNFL), ganglion cell layer to inner plexiform layer (GCL-IPL), and P100 pVEP latency were measured. Generalized estimating equation models were used to compare the groups, adjusting for age and intereye correlations...
July 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28616716/retinal-microstructures-are-altered-in-patients-with-idiopathic-infantile-nystagmus
#14
Jinu Han, Taekjune Lee, Jong Bok Lee, Sueng-Han Han
PURPOSE: To compare segmented retinal layer thicknesses between patients with idiopathic infantile nystagmus (IIN) and controls. METHODS: This retrospective case-control study included 66 patients with IIN and 66 age-matched controls. The retinal layers were examined using spectral domain optical coherence tomography with autosegmentation. Central foveal thickness (CFT), outer nuclear layer (ONL), and outer segment length (OSL) thickness were measured at the fovea center...
June 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28616715/effects-of-intravitreal-injection-of-bevacizumab-with-or-without-anterior-chamber-paracentesis-on-intraocular-pressure-and-peripapillary-retinal-nerve-fiber-layer-thickness-a-prospective-study
#15
Masoud Soheilian, Saeed Karimi, Talieh Montahae, Homayoun Nikkhah, Seyed Aliasghar Mosavi
PURPOSE: To investigate the effects of intravitreal injection of bevacizumab (IVB) with or without anterior chamber paracentesis on intraocular pressure (IOP) and peripapillary retinal nerve fiber layer (PRNFL) thickness. METHODS: In this prospective randomized clinical trial, 90 eyes with center involving diabetic macular edema or wet type age-related macular degeneration (AMD) were randomly assigned to receive IVB either without (group A) or with (group B) anterior chamber paracentesis...
June 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28615925/anterior-lamina-cribrosa-surface-depth-in-healthy-saudi-females
#16
Amira El-Agamy, Fayrouz Oteaf, Mohamed Berika
PURPOSE: This study was conducted to determine normative profile of anterior lamina cribrosa surface depth (ALCSD) in healthy Saudi females using Topcon Three-Dimensional (3D) Optical Coherence Tomography (OCT) 2000 - Spectral Domain (SD-OCT). In addition, the correlation between ALCSD and other clinical factors such as age, refractive error, intraocular pressure (IOP), central corneal thickness, anterior chamber depth, axial length, retinal nerve fiber layer thickness, and disk area was also assessed...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28613353/retinal-ganglion-cell-loss-in-children-with-type-1-diabetes-mellitus-without-diabetic-retinopathy
#17
Omer Karti, Ozlem Nalbantoglu, Saygin Abali, Ziya Ayhan, Selma Tunc, Tuncay Kusbeci, Behzat Ozkan
BACKGROUND AND OBJECTIVE: Early diabetic retinal changes in children with type 1 diabetes mellitus (T1DM) without diabetic retinopathy (DR) were examined using spectral-domain optical coherence tomography (SD-OCT). PATIENTS AND METHODS: Sixty children with T1DM without DR and 60 normal children were enrolled in the study. SD-OCT was used to measure the ganglion cell-inner plexiform layer (GC-IPL) and retinal nerve fiber (RNFL) thicknesses in all participants. RESULTS: The GC-IPL thickness was significantly decreased in all quadrants except the superior-nasal quadrant in children with diabetes (P < ...
June 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28611153/effects-of-short-term-mild-hypercapnia-during-head-down-tilt-on-intracranial-pressure-and-ocular-structures-in-healthy-human-subjects
#18
Steven S Laurie, Gianmarco Vizzeri, Giovanni Taibbi, Connor R Ferguson, Xiao Hu, Stuart M C Lee, Robert Ploutz-Snyder, Scott M Smith, Sara R Zwart, Michael B Stenger
Many astronauts experience ocular structural and functional changes during long-duration spaceflight, including choroidal folds, optic disc edema, globe flattening, optic nerve sheath diameter (ONSD) distension, retinal nerve fiber layer thickening, and decreased visual acuity. The leading hypothesis suggests that weightlessness-induced cephalad fluid shifts increase intracranial pressure (ICP), which contributes to the ocular structural changes, but elevated ambient CO2 levels on the International Space Station may also be a factor...
June 2017: Physiological Reports
https://www.readbyqxmd.com/read/28605811/parapapillary-deep-layer-microvasculature-dropout-in-glaucoma-topographic-association-with-glaucomatous-damage
#19
Eun Ji Lee, Seung Hyen Lee, Jeong-Ah Kim, Tae-Woo Kim
Purpose: The purpose of this article was to compare the frequencies of the parapapillary deep-layer microvasculature dropout (MvD) detected by optical coherence tomography angiography in eyes with primary open-angle glaucoma (POAG) and healthy eyes and to determine the topographic correlation between the MvD and the glaucomatous retinal nerve fiber layer (RNFL) defect in POAG eyes. Methods: Microvasculature in the peripapillary deep-layer was evaluated in 150 POAG patients and 45 healthy controls using swept-source optical coherence tomography angiography to identify an MvD...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28601911/repeatability-of-ganglion-cell-inner-plexiform-layer-thickness-measurements-using-spectral-domain-oct-in-branch-retinal-vein-occlusion
#20
Yeon Hee Lee, Min-Su Kim, Seung Il Ahn, Hye Jin Park, Kyung Sup Shin, Jung-Yeul Kim
PURPOSE: To analyze the repeatability of thickness measurements of the central macula, ganglion cell-inner plexiform layer (GC-IPL), and retinal nerve fiber layer (RNFL) using spectral-domain optical coherence tomography (SD-OCT) before and after treatment of macular edema in branch retinal vein occlusion (BRVO). METHODS: We analyzed patients with BRVO who visited our retinal clinic. The repeatability of the thickness measurements were compared using the intraclass correlation coefficient (ICC) and coefficient of variation (COV) of affected versus normal fellow eyes...
June 11, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
keyword
keyword
29314
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"