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Choroidal thickness

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https://www.readbyqxmd.com/read/29454660/development-and-course-of-scars-in-the-comparison-of-age-related-macular-degeneration-treatments-trials
#1
Ebenezer Daniel, Wei Pan, Gui-Shuang Ying, Benjamin J Kim, Juan E Grunwald, Frederick L Ferris, Glenn J Jaffe, Cynthia A Toth, Daniel F Martin, Stuart L Fine, Maureen G Maguire
PURPOSE: To describe risk factors for scar formation and changes to fibrotic scar through 5 years in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). DESIGN: Multicenter, prospective cohort study. PARTICIPANTS: A total of 1061 subjects in CATT. METHODS: Color photographic and fluorescein angiographic images from baseline and 1, 2, and 5 years were evaluated. Incidence of scar formation was estimated with Kaplan-Meier curves...
February 14, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29454631/update-on-visual-function-and-choroidal-retinal-thickness-alterations-in-parkinson-s-disease
#2
J Obis, M Satue, R Alarcia, L E Pablo, E Garcia-Martin
Parkinson's disease (PD) is a neurodegenerative process that affects 7.5 million people around the world. Since 2004, several studies have demonstrated changes in various retinal layers in PD using optical coherence tomography (OCT). However, there are some discrepancies in the results of those studies. Some of them have correlated retinal thickness with the severity or duration of the disease, demonstrating that OCT measurements may be an innocuous and easy biomarker for PD progression. Other studies have demonstrated visual dysfunctions since early phases of the disease...
February 14, 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29451995/sex-dependent-choroidal-thickness-differences-in-healthy-adults-a-study-based-on-original-and-synthesized-data
#3
Wei Wang, Miao He, Xingwu Zhong
PURPOSE: The purpose of this study is to determine the influence of sex on choroidal thickness (CT) in healthy adults. METHODS: Healthy Chinese adults were recruited and complete ophthalmic examinations were performed. The choroid was imaged by swept-source optical coherence tomography and the macular CT in Early Treatment Diabetic Retinopathy Study grids was obtained by the intrinsic automated segmentation software. CT in males and females was compared after controlling other factors...
February 16, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29450380/can-optical-coherence-tomography-redefine-amblyopia
#4
REVIEW
Elena Avram
Introduction: For many years, amblyopia was regarded as a disorder of the visual system in which an organic cause could not be identified. Optical Coherence Tomography opens new horizons in understanding the etiopathology of amblyopia and seems to highlight morphologic anomalies in the retina of the amblyopic eye. Purpose: The objective of this paper is to analyze the macular thickness, optic nerve changes, and choroidal thickness found in patients diagnosed with amblyopia based on trials reported in the literature...
April 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29448041/vip-changes-during-daytime-in-chicken-intrinsic-choroidal-neurons
#5
Bettina Hohberger, Carmen Jessberger, Matthias Zenkel, Alexandra Kaser-Eichberger, Antonio Bergua, Falk Schrödl, Winfried Neuhuber
PURPOSE: Ocular autonomic control is mediated by sympathetic and parasympathetic nerve fibres. Their interactions are complemented by primary afferent nerve fibers of and intrinsic choroidal neurons (ICN). As the vasodilatative neuropeptide, vasoactive intestinal peptide (VIP), is expressed in extrinsic and intrinsic ocular neurons, it is of special interest in ophthalmic research. Since circadian changes of ocular blood flow are known in humans and birds, this study aimed at investigating VIP expression at different daytimes in chicken choroid, the preferred model species in ICN research...
February 12, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29443802/full-thickness-macular-hole-with-macular-intrachoroidal-cavitation-in-a-patient-with-pathologic-myopia
#6
Nurgül Örnek, Kemal Örnek
PURPOSE: To describe a full-thickness macular hole (MH) opening to macular intrachoroidal cavitation in a patient with pathologic myopia. METHODS: Full ophthalmologic examination, fundus camera (Topcon TRC; Topcon Co, Tokyo, Japan), optical coherence tomography (RetinaScan Advanced RS-3000; NIDEK, Gamagori, Japan) imaging, and cataract surgery. RESULTS: A 61-year-old woman admitted with decreased vision in the left eye. Visual acuity was counting fingers from 30 cm...
February 13, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29443798/clinical-features-imaging-and-natural-history-of-myelinated-retinal-nerve-fiber-layer
#7
Raksha Rao, Elif B Turkoglu, Emil A T Say, Carol L Shields
PURPOSE: To evaluate the natural history of myelinated retinal nerve fiber layer (MRNFL) through clinical features and enhanced depth imaging optical coherence tomography. METHODS: This is a retrospective, noncomparative, case series of patients who underwent thorough clinical examination to document associated ocular and systemic features. Enhanced depth imaging optical coherence tomography was performed when MRNFL was located posteriorly and accessible to imaging...
February 13, 2018: Retina
https://www.readbyqxmd.com/read/29443029/in-vivo-multimodal-imaging-and-analysis-of-mouse-laser-induced-choroidal-neovascularization-model
#8
Symantas Ragauskas, Eva Kielczewski, Joseph Vance, Simon Kaja, Giedrius Kalesnykas
Laser-induced choroidal neovascularization (CNV) is a well-established model to mimic the wet form of age-related macular degeneration (AMD). In this protocol, we aim to guide the reader not simply through the technical considerations of generating laser-induced lesions to trigger neovascular processes, but rather focus on the powerful information that can be obtained from multimodal longitudinal in vivo imaging throughout the follow-up period. The laser-induced mouse CNV model was generated by a diode laser administration...
January 21, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29442283/eplerenone-versus-observation-in-the-treatment-of-acute-central-serous-chorioretinopathy-a-retrospective-controlled-study
#9
Ilaria Zucchiatti, Riccardo Sacconi, Maria Cristina Parravano, Eliana Costanzo, Lea Querques, Daniela Montorio, Francesco Bandello, Giuseppe Querques
INTRODUCTION: To investigate the effects of eplerenone compared to observation in the treatment of acute central serous chorioretinopathy (CSC). METHODS: Charts of consecutive patients with a diagnosis of acute CSC (visual symptoms < 12 weeks) were reviewed. Included patients were divided into a treatment group (treated with eplerenone) and a control group (observation). Main outcome measures included changes in best-corrected visual acuity (BCVA), central macular thickness (CMT), height of subretinal fluid (SRF) and subfoveal choroidal thickness (CT) at 1 and 3 months in the two groups...
February 13, 2018: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/29434739/intravitreal-ranibizumab-injection-combined-with-photodynamic-therapy-for-polypoidal-choroidal-vasculopathy
#10
Jia Li, Jianhua Sun, Bing Li, Zheli Liu
The aim of the present study was to evaluate the efficacy of combination treatment with intravitreal ranibizumab (IVR) injection and photodynamic therapy (PDT) for polypoidal choroidal vasculopathy (PCV). A total of 64 patients with PCV were included in the present study, which were divided into the IVR monotherapy group (Group A) and combination treatment groups (Groups B-D) with different treatment intervals. All subjects were followed-up at 1, 3, 6 and 12 months following treatment, and subjected to the detection of best-corrected visual acuity (BCVA) and central foveal thickness (CFT)...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29429986/comparison-of-photodynamic-therapy-and-navigated-microsecond-laser-for-chronic-central-serous-chorioretinopathy
#11
Cyprian Gabriel Ntomoka, Bindu Rajesh, Gachago Muchai Muriithi, Abhilash Goud, Jay Chhablani
OBJECTIVES: To compare the visual and anatomical outcomes after photodynamic therapy (PDT) and navigated microsecond laser (nMSL) for chronic central serous chorioretinopathy (CSCR). METHODS: This retrospective study included eyes with chronic CSCR who underwent either PDT or nMSL with a minimum of 6 months' follow-up. Eyes with a history of treatment with any other modalities in the past or during 6 months post PDT or microsecond laser follow-up were excluded. Primary outcome measures included change in best-corrected visual acuity (BCVA) and central macular thickness (CMT)...
February 12, 2018: Eye
https://www.readbyqxmd.com/read/29426443/choroidal-thickness-changes-following-cataract-surgery-using-swept-source-optical-coherence-tomography
#12
Rida Shahzad, M A Rehman Siddiqui, Sidra Zafar, Farzana Kausar, Masroor H Shahzad
OBJECTIVE: The aim of this study was to assess changes in subfoveal choroidal thickness (SFCT), measured using swept-source optical coherence tomography (SS-OCT), after routine phacoemulsification cataract surgery. DESIGN: This is a prospective, interventional, controlled study that took place at Shahzad Eye Hospital, Karachi, Pakistan, between February 2015 and January 2016. PARTICIPANTS: One hundred and one patients who were undergoing routine cataract surgery were recruited...
February 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29424884/clinical-research-on-one-third-dose-verteporfin-photodynamic-therapy-in-the-treatment-of-chronic-central-serous-chorioretinopathy
#13
L Hua, B Lin, J Hong, H-B Min, W-L Han, T-Y Zhou, Z-Q Zhang
OBJECTIVE: To observe the curative effect and safety of one-third dose Verteporfin photodynamic therapy (PDT) in the treatment of chronic central serous chorioretinopathy (CSC). PATIENTS AND METHODS: A total of 60 patients (68 eyes) treated in our hospital from January 2016 to December 2016 were selected in this study, and they were diagnosed with chronic CSC via fluorescein fundus angiography (FFA), indocyanine green angiography (ICGA) and optical coherence tomography (OCT)...
January 2018: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29423278/comparative-analysis-of-choroidal-thickness-in-third-trimester-pregnant-women
#14
Camila Zanella Benfica, Teresinha Zanella, Lucas Brandolt Farias, Maria Lúcia Rocha Oppermann, Luis Henrique Santos Canani, Daniel Lavinsky
Background: The impact of pregnancy on the choroid is still under investigation. The aim of this study is to compare choroidal thickness measurements of healthy pregnant women in the third trimester and healthy non-pregnant women using spectral-domain optical coherence tomography (OCT). Methods: This cross-sectional study included 122 eyes of 61 women, divided into two groups: 27 healthy pregnant women in the third trimester and 34 age-matched healthy non-pregnant women...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29420622/study-of-retina-and-choroid-biological-parameters-of-rhesus-monkeys-eyes-on-scleral-collagen-cross-linking-by-riboflavin-and-ultraviolet-a
#15
Mingshen Sun, Fengju Zhang, Bowen Ouyang, Mengmeng Wang, Yu Li, Xuan Jiao, Li Zhang, Ningli Wang
To evaluate ocular fundus biological changes after scleral collagen cross-linking (CXL) with riboflavin/ ultraviolet A (UVA) on rhesus monkeys in vivo by analyzing retina and choroid biological parameters. Six 3-year-old male rhesus monkeys (12 eyes) were observed in this study, with scleral CXL procedures applied on superior temporal equatorial sclera on random eyes of all rhesus. Optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) examination were performed before and 1 week, 1 month, 3 months and 6 months after CXL...
2018: PloS One
https://www.readbyqxmd.com/read/29414835/choroidal-thickness-with-swept-source-optical-coherence-tomography-versus-foveal-morphology-in-young-children-with-a-history-of-prematurity
#16
Wadim Bowl, Marianne Bowl, Silke Schweinfurth, Kerstin Holve, Monika Andrassi-Darida, Knut Stieger, Birgit Lorenz
AIM: Comparison of choroidal thickness (CT) and foveal morphology as seen with swept-source optical coherence tomography (SS-OCT) in children with a history of treated or spontaneously regressed retinopathy of prematurity (tROP or srROP) to assess the impact on best-corrected visual acuity (BCVA). METHODS: CT was measured by SS-OCT (DRI-OCT Triton; Topcon, USA) single scans of a 6-mm diameter around the fovea in 17 children with tROP or srROP (4-7 years of age) and compared to 25 controls (age-matched children and adults)...
February 7, 2018: Ophthalmic Research
https://www.readbyqxmd.com/read/29411171/efficacy-of-treat-and-extend-regimen-with-aflibercept-for-pachychoroid-neovasculopathy-and-type-1-neovascular-age-related-macular-degeneration
#17
Hidetaka Matsumoto, Takashi Hiroe, Masahiro Morimoto, Kensuke Mimura, Arisa Ito, Hideo Akiyama
PURPOSE: To evaluate the efficacy of intravitreal aflibercept therapy using a treat-and-extend regimen on treatment-naïve pachychoroid neovasculopathy (PNV) and Type 1 neovascular age-related macular degeneration (AMD). METHODS: We retrospectively studied 42 eyes with PNV and 60 eyes with Type 1 neovascular AMD. We assessed best-corrected visual acuity (BCVA), central macular thickness (CMT), central choroidal thickness (CCT), and total number of injections over 2 years...
February 6, 2018: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29409899/a-12-year-study-of-slotted-palladium-103-plaque-radiation-therapy-for-choroidal-melanoma-near-touching-or-surrounding-the-optic-nerve
#18
Abhilasha Maheshwari, Paul T Finger
PURPOSE: To present our 12-year experience with low energy photon, slotted eye plaque radiation therapy. DESIGN: Retrospective interventional case series METHODS: SETTING: The New York Eye Cancer Center. STUDY POPULATION: Fifty-two consecutive patients with uveal melanomas near, touching or surrounding the optic disc. INTERVENTION: Slotted eye plaque radiation therapy. MAIN OUTCOME MEASURES: change in visual acuity, local tumor control, radiation side effects, eye salvage and systemic metastases...
January 31, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29409880/the-effects-of-graded-intraocular-pressure-challenge-on-the-optic-nerve-head
#19
Nimesh Patel, Faith McAllister, Laura Pardon, Ronald Harwerth
Intraocular pressure (IOP) is an important risk factor for glaucoma, and the response of the ONH and surrounding tissues to elevated IOP are often investigated to better understand pathophysiology. In vivo structure including that of the optic nerve head (ONH) and surrounding tissue of the eye are often assessed using optical coherence tomography (OCT). With advances in OCT technology, both large vessels and capillaries can be imaged non-invasively (OCT Angiography). Because a significant portion of retinal thickness is comprised of vasculature, the purpose of the current study was to investigate OCT structural and vascular changes in healthy non-human primate eyes with systematic graded increases and decreases in IOP...
February 1, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29409857/early-choriocapillaris-changes-after-half-fluence-photodynamic-therapy-in-chronic-central-serous-chorioretinopathy-evaluated-by-optical-coherence-tomography-angiography-preliminary-results
#20
Ali Demircan, Ceren Yesilkaya, Zeynep Alkin
BACKGROUND: The purpose of this study is to examine the choridal perfusion in patients with chronic central serous chorioretinopathy (CSC) after half-fluence photodynamic therapy (PDT) in the early post-treatment period. METHODS: This retrospective study included patients with chronic CSC. Indocyanine green angiography (ICGA) guided half-fluence PDT was applied to the all eyes. Best corrected visual acuity (BCVA) was assessed by Snellen chart and central retinal thickness (CRT) and subfoveal choroidal thickness (SFCT) was measured by spectral domain optical coherence tomography (SD-OCT) before PDT and at 3 and 30 days following the therapy...
February 1, 2018: Photodiagnosis and Photodynamic Therapy
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