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Fernando baquero

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https://www.readbyqxmd.com/read/29620743/sciences-unite-in-spain-to-promote-research-for-advancing-society
#1
Fernando Baquero, Jose A Gutiérrez-Fuentes
No abstract text is available yet for this article.
April 5, 2018: Nature
https://www.readbyqxmd.com/read/29559105/bayesian-spatial-models-of-the-association-between-interpersonal-violence-animal-abuse-and-social-vulnerability-in-s%C3%A3-o-paulo-brazil
#2
Oswaldo Santos Baquero, Fernando Ferreira, Marcelo Robis, José Soares Ferreira Neto, Jason Ardila Onell
Animal abuse adversely affects animal health and welfare and has been associated with interpersonal violence in studies of individuals. However, if that association also depends on sociocultural contexts and can be detected on a geographic scale, a wider source of data can be used to identify risk areas to support the surveillance of both types of violence. In this study, we evaluated the association between interpersonal violence notifications, animal abuse notifications and an index of social vulnerability in São Paulo City, on a geographic scale, using Bayesian spatial models...
April 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29533348/re-mycobacterial-disease-in-immunocompromised-children-in-a-high-endemic-area
#3
Begoña Santiago-García, María José Mellado-Peña, Fernando Baquero-Artigao, Jesús Ruiz Contreras
No abstract text is available yet for this article.
April 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29496104/validity-of-a-two-stage-cluster-sampling-design-to-estimate-the-total-number-of-owned-dogs
#4
Oswaldo Santos Baquero, Marcos Amaku, Ricardo Augusto Dias, José Henrique Hildebrand Grisi Filho, José Soares Ferreira Neto, Fernando Ferreira
Estimates of owned dog population size are necessary to calculate measures of disease frequency and to plan and evaluate population management programs. We calculated the error and bias of estimates of the total number of owned dogs using a two-stage cluster sampling design. The estimates were conditioned on sample composition as well as on size and heterogeneity of the spatial distribution of owned dog populations. For this, we simulated nine cities that differed systematically in size (number of census tracts) and heterogeneity (variance of the number of dogs per census tract)...
March 1, 2018: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/29335005/in-depth-resistome-analysis-by-targeted-metagenomics
#5
Val F Lanza, Fernando Baquero, José Luís Martínez, Ricardo Ramos-Ruíz, Bruno González-Zorn, Antoine Andremont, Antonio Sánchez-Valenzuela, Stanislav Dusko Ehrlich, Sean Kennedy, Etienne Ruppé, Willem van Schaik, Rob J Willems, Fernando de la Cruz, Teresa M Coque
BACKGROUND: Antimicrobial resistance is a major global health challenge. Metagenomics allows analyzing the presence and dynamics of "resistomes" (the ensemble of genes encoding antimicrobial resistance in a given microbiome) in disparate microbial ecosystems. However, the low sensitivity and specificity of available metagenomic methods preclude the detection of minority populations (often present below their detection threshold) and/or the identification of allelic variants that differ in the resulting phenotype...
January 15, 2018: Microbiome
https://www.readbyqxmd.com/read/29224998/neonatal-epididymo-orchitis-with-pyocele-caused-by-escherichia-coli-successful-treatment-with-antimicrobial-therapy-alone
#6
David Aguilera-Alonso, Teresa Del Rosal, Sara Pérez Muñoz, Fernando Baquero-Artigao
No abstract text is available yet for this article.
December 7, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29184022/interventions-on-metabolism-making-antibiotic-susceptible-bacteria
#7
Fernando Baquero, José-Luis Martínez
Antibiotics act on bacterial metabolism, and antibiotic resistance involves changes in this metabolism. Interventions on metabolism with drugs might therefore modify drug susceptibility and drug resistance. In their recent article, Martin Vestergaard et al. (mBio 8:e01114-17, 2017, https://doi.org/10.1128/mBio.01114-17) illustrate the possibility of converting intrinsically resistant bacteria into susceptible ones. They reported that inhibition of a central metabolic enzyme, ATP synthase, allows otherwise ineffective polymyxin antibiotics to act on Staphylococcus aureus The study of the intrinsic resistome of bacterial pathogens has shown that several metabolic genes, including multigene transcriptional regulators, contribute to antibiotic resistance...
November 28, 2017: MBio
https://www.readbyqxmd.com/read/29136422/transmission-as-a-basic-process-in-microbial-biology-lwoff-award-prize-lecture
#8
Fernando Baquero
Transmission is a basic process in biology and evolution, as it communicates different biological entities within and across hierarchical levels (from genes to holobionts) both in time and space. Vertical descent, replication, is transmission of information across generations (in the time dimension), and horizontal descent is transmission of information across compartments (in the space dimension). Transmission is essentially a communication process that can be studied by analogy of the classic information theory, based on 'emitters', 'messages' and 'receivers'...
November 1, 2017: FEMS Microbiology Reviews
https://www.readbyqxmd.com/read/28951476/individual-patterns-of-complexity-in-cystic-fibrosis-lung-microbiota-including-predator-bacteria-over-a-1-year-period
#9
Juan de Dios Caballero, Rafael Vida, Marta Cobo, Luis Máiz, Lucrecia Suárez, Javier Galeano, Fernando Baquero, Rafael Cantón, Rosa Del Campo
Cystic fibrosis (CF) lung microbiota composition has recently been redefined by the application of next-generation sequencing (NGS) tools, identifying, among others, previously undescribed anaerobic and uncultivable bacteria. In the present study, we monitored the fluctuations of this ecosystem in 15 CF patients during a 1-year follow-up period, describing for the first time, as far as we know, the presence of predator bacteria in the CF lung microbiome. In addition, a new computational model was developed to ascertain the hypothetical ecological repercussions of a prey-predator interaction in CF lung microbial communities...
September 26, 2017: MBio
https://www.readbyqxmd.com/read/28859345/basic-sciences-fertilizing-clinical-microbiology-and-infection-management
#10
Fernando Baquero
Basic sciences constitute the most abundant sources of creativity and innovation, as they are based on the passion of knowing. Basic knowledge, in close and fertile contact with medical and public health needs, produces distinct advancements in applied sciences. Basic sciences play the role of stem cells, providing material and semantics to construct differentiated tissues and organisms and enabling specialized functions and applications. However, eventually processes of "practice deconstruction" might reveal basic questions, as in de-differentiation of tissue cells...
August 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28859340/rewiring-microbiology-and-infection
#11
Didier Raoult, Fernando Baquero
No abstract text is available yet for this article.
August 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28843668/phagocytes-antibiotics-and-self-limiting-bacterial-infections
#12
REVIEW
Bruce R Levin, Fernando Baquero, Peter Pierre Ankomah, Ingrid C McCall
Most antibiotic use in humans is to reduce the magnitude and term of morbidity of acute, community-acquired infections in immune competent patients, rather than to save lives. Thanks to phagocytic leucocytes and other host defenses, the vast majority of these infections are self-limiting. Nevertheless, there has been a negligible amount of consideration of the contribution of phagocytosis and other host defenses in the research for, and the design of, antibiotic treatment regimens, which hyper-emphasizes antibiotics as if they were the sole mechanism responsible for the clearance of infections...
November 2017: Trends in Microbiology
https://www.readbyqxmd.com/read/28729186/-tuberculosis-treatment-for-children-an-update
#13
María José Mellado Peña, Begoña Santiago García, Fernando Baquero-Artigao, David Moreno Pérez, Roi Piñeiro Pérez, Ana Méndez Echevarría, José Tomás Ramos Amador, David Gómez-Pastrana Durán, Antoni Noguera Julian
Tuberculosis (TB) is the most important infectious disease all over the world, with a high morbidity and mortality. Pediatric tuberculosis has been a neglected epidemic, due to the difficulties in assessing its global impact, reduced incidence and lower infectivity compared to adults. In 2015, the WHO reported 1 million cases of paediatric TB and 169,000 deaths. In Europe, the emergence of MDR TB is a major concern, representing 16% of the new diagnosis in Eastern Europe. In 2014, it was estimated that about 219,000 children were infected by MDR-TB-strains in Europe, and 2,120 developed the disease...
January 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28711388/impact-of-13-valent-pneumococcal-conjugate-vaccine-on-pneumococcal-meningitis-in-children
#14
Jesus Ruiz-Contreras, Juan Picazo, Juan Casado-Flores, Fernando Baquero-Artigao, Teresa Hernández-Sampelayo, Enrique Otheo, Cristina Méndez, María Del Amo, César Balseiro
OBJECTIVES: To evaluate the impact of 13-valent pneumococcal conjugate vaccine on pneumococcal meningitis in children. METHODS: Children younger than 15years of age attending 27 hospitals in the Region of Madrid with confirmed pneumococcal meningitis were identified in a prospective surveillance study, from 2007 to 2015. Clinical data, neurological sequelae, pneumococcal vaccination status, serotyping and antibiotic susceptibility were recorded. RESULTS: One hundred and four cases of pneumococcal meningitis were identified, 63 during the period of routine 7-valent pneumococcal conjugate vaccine immunisation (May 2007-April 2010) and 41 during the period of 13-valent pneumococcal conjugate vaccine immunisation (May 2010-April 2015)...
August 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28689671/detection-of-toxigenic-clostridium-difficile-in-paediatric-patients
#15
Iker Falces-Romero, Paloma Troyano-Hernáez, Silvia García-Bujalance, Fernando Baquero-Artigao, María José Mellado-Peña, Julio García-Rodríguez
INTRODUCTION: Our main objective was a revision of clinical, microbiological and epidemiological results of Clostridium difficile-associated infection in paediatric patients (2010-2015). We compared the diagnoses performed by detection of toxins in feces and those performed by real-time PCR. METHODS: This retrospective study included 82 paediatric patients. Detection of toxigenic C. difficile was performed sequentially, in diarrheal feces and under clinical request...
July 6, 2017: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/28684093/-osteoarticular-tuberculosis-in-paediatrics-a-review-of-20-years-of-cases-in-a-tertiary-hospital
#16
María José Pérez Durán, Bárbara Moreno Sanz-Gadea, Teresa Del Rosal Raves, María José Mellado Peña, Fernando Baquero-Artigao
No abstract text is available yet for this article.
November 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28479006/-pyomyositis-in-a-non-tropical-area-12-years-of-cased-based-experience
#17
Beatriz González Gómez, Manuel Vargas Pérez, Teresa Del Rosal Rabes, Franciso Javier Aracil Santos, Fernando Baquero-Artigao
No abstract text is available yet for this article.
December 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28443682/abandonment-of-dogs-and-cats-public-opinions-as-population-management-indicators
#18
Oswaldo Santos Baquero, Evelyn Nestori Chiozzotto, Rita de Cassia Maria Garcia, Marcos Amaku, Fernando Ferreira
This study involved characterizing public opinions on selected issues related to the abandonment of dogs and cats in Votorantim, São Paulo, Brazil. This goal was achieved by applying multiple correspondence analysis to answers recorded in questionnaires of a population-based survey. The results suggest that the tolerance of potentially problematic behaviors did not depend on the specific kind of behavior, at least among the behaviors evaluated. The opinions given for the most frequent fate of the companion animals did not depend on the species, and those who considered abandonment to be one of the most frequent fates tended to also consider abandonment as a solution to problematic behaviors...
July 2017: Journal of Applied Animal Welfare Science: JAAWS
https://www.readbyqxmd.com/read/28363363/dexamethasone-for-parapneumonic-pleural-effusion-a-randomized-double-blind-clinical-trial
#19
RANDOMIZED CONTROLLED TRIAL
Alfredo Tagarro, Enrique Otheo, Fernando Baquero-Artigao, María-Luisa Navarro, Rosa Velasco, Marta Ruiz, María Penín, David Moreno, Pablo Rojo, Rosario Madero
OBJECTIVE: To assess whether dexamethasone (DXM) decreases the time to recovery in patients with parapneumonic pleural effusion. STUDY DESIGN: This was a multicenter, randomized, double blind, parallel-group, placebo-controlled clinical trial of 60 children, ranging in age from 1 month to 14 years, with community-acquired pneumonia (CAP) and pleural effusion. Patients received either intravenous DXM (0.25?mg/kg/dose) or placebo every 6 hours over a period of 48 hours, along with antibiotics...
June 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28360174/complete-genome-sequences-of-isolates-of-enterococcus-faecium-sequence-type-117-a-globally-disseminated-multidrug-resistant-clone
#20
Ana P Tedim, Val F Lanza, Marina Manrique, Eduardo Pareja, Patricia Ruiz-Garbajosa, Rafael Cantón, Fernando Baquero, Teresa M Coque, Raquel Tobes
The emergence of nosocomial infections by multidrug-resistant sequence type 117 (ST117) Enterococcus faecium has been reported in several European countries. ST117 has been detected in Spanish hospitals as one of the main causes of bloodstream infections. We analyzed genome variations of ST117 strains isolated in Madrid and describe the first ST117 closed genome sequences.
March 30, 2017: Genome Announcements
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