Timo Kahles, Patrik Michel, Alexander Hapfelmeier, Franz R Eberli, Marialuisa Zedde, Vincent Thijs, Markus Kraemer, Stefan T Engelter, Joaquin Serena, Christian Weimar, Achim Mallmann, Andreas Luft, Dimitri Hemelsoet, David E Thaler, Andreas Müller-Eichelberg, Adinda De Pauw, Roman Sztajzel, Carmel Armon, David M Kent, Bernhard Meier, Heinrich P Mattle, Urs Fischer, Marcel Arnold, Marie-Luise Mono, Krassen Nedeltchev
Background and Purpose: To identify factors associated with prior stroke at presentation in patients with cryptogenic stroke (CS) and patent foramen ovale (PFO). Methods: We studied cross-sectional data from the International PFO Consortium Study (NCT00859885). Patients with first-ever stroke and those with prior stroke at baseline were analyzed for an association with PFO-related (right-to-left shunt at rest, atrial septal aneurysm, deep venous thrombosis, pulmonary embolism, and Valsalva maneuver) and PFO-unrelated factors (age, gender, BMI, hypertension, diabetes mellitus, hypercholesterolemia, smoking, migraine, coronary artery disease, aortic plaque)...
2020: Frontiers in Neurology