Ning Xia, Jie Wang, Qiuting Guo, Jiawei Duan, Xuan Wang, Peijie Zhou, Jinkai Li, Tiantian Tang, Taotao Li, Huiting Li, Zhenfeng Wu, Ming Yang, Jing Sun, Dongyan Guo, Xing Chang, Xiaofei Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Rosa damascena is an ancient plant with significance in both medicine and perfumery that have a variety of therapeutic properties, including antidepressant, anti-anxiety, and anti-stress effects. Rose damascena essential oil (REO) has been used to treat depression, anxiety and other neurological related disorders in Iranian traditional medicine. However, its precise mechanism of action remains elusive. AIM OF THE STUDY: The aim of this study was to investigate the impact and mechanism underlying the influence of REO on chronic unpredictable mild stress (CUMS) rats...
March 14, 2024: Journal of Ethnopharmacology