Afif P Jati, Pedro J Sola-Campoy, Thijs Bosch, Leo M Schouls, Antoni P A Hendrickx, Verónica Bautista, Noelia Lara, Erwin Raangs, Belén Aracil, John W A Rossen, Alex W Friedrich, Ana M Navarro Riaza, Javier E Cañada-García, Eva Ramírez de Arellano, Jesús Oteo-Iglesias, María Pérez-Vázquez, Silvia García-Cobos, Ana María Fernández Sánchez, Ma Angeles Pulido, Mayuli Armas
In this study, we determined the presence of virulence factors in nonoutbreak, high-risk clones and other isolates belonging to less common sequence types associated with the spread of OXA-48-producing Klebsiella pneumoniae clinical isolates from The Netherlands ( n = 61) and Spain ( n = 53). Most isolates shared a chromosomally encoded core of virulence factors, including the enterobactin gene cluster, fimbrial fim and mrk gene clusters, and urea metabolism genes ( ureAD ). We observed a high diversity of K-Locus and K/O loci combinations, KL17 and KL24 (both 16%), and the O1/O2v1 locus (51%) being the most prevalent in our study...
June 13, 2023: Microbiology Spectrum