keyword
MENU ▼
Read by QxMD icon Read
search

ST101 Escherichia

keyword
https://www.readbyqxmd.com/read/29565227/prevalence-of-extended-spectrum-beta-lactamase-and-carbapenemase-genes-in-clinical-isolates-of-escherichia-coli-in-myanmar-dominance-of-bla-ndm-5-and-emergence-of-bla-oxa-181
#1
Meiji Soe Aung, Nilar San, Win Win Maw, Thida San, Noriko Urushibara, Mitsuyo Kawaguchiya, Ayako Sumi, Nobumichi Kobayashi
The increasing trend of Escherichia coli producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is a global public health concern. In this study, prevalence and molecular characteristics of E. coli harboring ESBL and carbapenemase genes were investigated for 426 isolates derived from various clinical specimens in a teaching hospital in Yangon, Myanmar, for the 1-year period beginning January 2016. A total of 157 isolates (36.9%) were ESBL producers and harbored CTX-M-1 group genes (146 isolates; blaCTX-M-15 , blaCTX-M55 ) or CTX-M-9 group genes (11 isolates; blaCTX-M-14 , blaCTX-M-27 )...
March 22, 2018: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/29535301/rapid-rise-of-the-esbl-and-mcr-1-genes-in-escherichia-coli-of-chicken-origin-in-china-2008-2014
#2
Congming Wu, Yingchao Wang, Xiaomin Shi, Shuang Wang, Hongwei Ren, Zhangqi Shen, Yang Wang, Juchun Lin, Shaolin Wang
Extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-EC) strains are emerging around the world as a source of resistance to β-lactam antibiotics such as ampicillin, cefotaxime, and ceftazidime. mcr-1 is a novel plasmid-mediated gene conferring resistance to colistin. The aim of this study was to investigate the prevalence of ESBL-EC mcr-1 of chicken origin in the different provinces of China during 2008-2014. Overall, 341 of 821 isolates were determined to be ESBL-EC strains, and the proportion of ESBL-positive strains almost doubled from 2008 to 2014...
March 14, 2018: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29507063/spread-of-plasmid-encoded-ndm-1-and-ges-5-carbapenemases-among-extensively-drug-resistant-and-pandrug-resistant-clinical-enterobacteriaceae-in-durban-south-africa
#3
Torunn Pedersen, John Osei Sekyere, Usha Govinden, Krishnee Moodley, Audun Sivertsen, Ørjan Samuelsen, Sabiha Yusuf Essack, Arnfinn Sundsfjord
Whole-genome sequence analyses revealed the presence of bla NDM-1 ( n =31), bla GES-5 ( n =8), bla OXA-232 ( n =1), or bla NDM-5 ( n =1) in extensively drug-resistant and pandrug-resistant Enterobacteriaceae isolated from in-patients in 10 private hospitals (2012-2013) in Durban, South Africa. Two novel NDM-1 encoding plasmids from Klebsiella pneumoniae were closed by PacBio sequencing. In p19-10_01 (IncFIB(K), 223.434 bp) bla NDM-1 was part of a Tn 1548 -like structure (16.276 bp) delineated by IS 26 The multireplicon plasmid p18-43_01 (IncR_1/IncFIB(pB171)/IncFII(Yp); 212...
March 5, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29326011/neonatal-intestinal-colonization-with-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-a-5-year-follow-up-study
#4
V Nordberg, K Jonsson, C G Giske, A Iversen, O Aspevall, B Jonsson, A Camporeale, M Norman, L Navér
OBJECTIVES: To analyse Klebsiella pneumoniae (KP) isolates from an outbreak of extended-spectrum β-lactamase (ESBL)-producing KP and Escherichia coli (EC) among infants admitted to neonatal intensive care units and to determine the duration of the intestinal colonization. METHODS: We performed a prospective cohort study of intestinal ESBL-KP/ESBL-EC colonized neonates after a 5-month outbreak in two neonatal intensive care units. Whole genome sequencing, multilocus sequence typing, core genome multilocus sequence typing, pulsed-field electrophoresis and PCR for blaCTX-M were performed on the first isolates...
January 8, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29237086/enterobacteriaceae-producing-oxa-48-like-carbapenemases-in-poland-2013-january-2017
#5
R Izdebski, A Baraniak, D Zabicka, M Machulska, P Urbanowicz, J Fiett, E Literacka, K Bojarska, A Kozinska, B Zieniuk, W Hryniewicz, M Gniadkowski
Objectives: To analyse OXA-48 (OXA-48/181)-type carbapenemase-producing Enterobacteriaceae reported in Poland from 2013 until January 2017. Methods: Bacterial isolates were typed by PFGE and MLST. Genes coding for OXA-48/181 types and other β-lactamases were amplified and sequenced. Mobile elements with blaOXA-48/181-like genes were PCR mapped. blaOXA-48/181-carrying plasmids were characterized by nuclease S1-hybridization profiling, transfer assays and PCR-based replicon typing, while the chromosomal location of the genes was confirmed by the I-CeuI analysis...
December 9, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28109845/outbreak-of-nosocomial-ndm-1-producing-klebsiella-pneumoniae-st1419-in-a-neonatal-unit
#6
Jing Yu, Yue Wang, Zhongju Chen, Xuhui Zhu, Lei Tian, Li Li, Ziyong Sun
OBJECTIVES: The aim of this study was to characterise carbapenem-resistant Klebsiella pneumoniae isolates recovered from neonatal clinical specimens over a 4-month period. METHODS: Seven carbapenem-resistant K. pneumoniae isolates were analysed. Antibiotic susceptibilities of the isolates were determined by the agar dilution method, and the drug resistance genes were evaluated by PCR. Clonal relatedness of the isolates was assessed using pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST)...
January 18, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/27965626/high-prevalence-of-gut-microbiota-colonization-with-broad-spectrum-cephalosporin-resistant-enterobacteriaceae-in-a-tunisian-intensive-care-unit
#7
Elaa Maamar, Sana Ferjani, Ali Jendoubi, Samia Hammami, Zaineb Hamzaoui, Laure Mayonnove-Coulange, Mabrouka Saidani, Aouatef Kammoun, Amel Rehaiem, Salma Ghedira, Mohamed Houissa, Ilhem Boutiba-Ben Boubaker, Amine Slim, Veronique Dubois
Healthcare-associated infections due to cefotaxime-resistant (CTX-R) Enterobacteriaceae have become a major public health threat, especially in intensive care units (ICUs). Often acquired nosocomially, CTX-R Enterobacteriaceae can be introduced initially by patients at admission. This study aimed to determine the prevalence and genetic characteristics of CTX-R Enterobacteriaceae-intestinal carriage in ICU patients, to evaluate the rate of acquisition of these organisms during hospitalization, and to explore some of the associated risk factors for both carriage and acquisition...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27855076/molecular-characterization-of-oxa-48-like-producing-enterobacteriaceae-in-the-czech-republic-and-evidence-for-horizontal-transfer-of-poxa-48-like-plasmids
#8
Anna Skalova, Katerina Chudejova, Veronika Rotova, Matej Medvecky, Vendula Studentova, Eva Chudackova, Pavel Lavicka, Tamara Bergerova, Vladislav Jakubu, Helena Zemlickova, Costas C Papagiannitsis, Jaroslav Hrabak
The aim of this study was to characterize the first cases and outbreaks of OXA-48-like-producing Enterobacteriaceae recovered from hospital settings in the Czech Republic. From 2013 to 2015, 22 Klebsiella pneumoniae isolates, 3 Escherichia coli isolates, and 1 Enterobacter cloacae isolate producing OXA-48-like carbapenemases were isolated from 20 patients. Four of the patients were colonized or infected by two or three different OXA-48-like producers. The K. pneumoniae isolates were classified into nine sequence types (STs), with ST101 being predominant (n = 8)...
February 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27790412/first-report-of-complete-sequence-of-a-bla-ndm-13-harboring-plasmid-from-an-escherichia-coli-st5138-clinical-isolate
#9
Jingnan Lv, Xiuqin Qi, Dan Zhang, Zhou Zheng, Yuehui Chen, Yinjuan Guo, Shanshan Wang, Liang Chen, Barry N Kreiswirth, Yi-Wei Tang, Zengqiang Chen, Longhua Hu, Liangxing Wang, Fangyou Yu
Since the first report of bla NDM-1 , 16 bla NDM variants have been identified among Gram-negative bacteria worldwide. Recently, a novel bla NDM variant, bla NDM-13 , was identified in the chromosome of an ST101 Escherichia coli isolate from Nepal. Here we first reported plasmid-mediated bla NDM-13 in a carbapenem-resistant E. coli ST5138 clinical isolate associated with hospital-acquired urinary tract infection from China. bla NDM-13 and bla SHV-12 coexisted on the a ~54 Kb self-transferable plasmid. Compared with NDM-1, NDM-13, NDM-3, and NDM-4 had two amino acid substitutions (D95N and M154L), one amino acid substitution (D95N) and one amino acid substitutions (M154L), respectively...
2016: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/27639859/increasing-incidence-of-carbapenemase-producing-escherichia-coli-and-klebsiella-pneumoniae-in-belgian-hospitals
#10
M De Laveleye, T D Huang, P Bogaerts, C Berhin, C Bauraing, P Sacré, A Noel, Y Glupczynski
Carbapenemase-producing Enterobacteriaceae are increasingly reported worldwide. The aim of the study was to determine the incidence and molecular epidemiology of carbapenemase-producing (CP) Escherichia coli and Klebsiella pneumoniae (CP-E/K) in Belgium. Eleven hospital-based laboratories collected carbapenem non-susceptible (CNS) isolates of E. coli and K. pneumoniae detected in clinical specimens from January 2013 to December 2014. All CNS strains were tested for carbapenemase production and typed by multilocus sequence typing (MLST) for a 6-month period as part of the European Survey on Carbapenemase-Producing Enterobacteriaceae in Europe (EuSCAPE) structured survey...
January 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/27503650/first-report-of-the-globally-disseminated-incx4-plasmid-carrying-the-mcr-1-gene-in-a-colistin-resistant-escherichia-coli-sequence-type-101-isolate-from-a-human-infection-in-brazil
#11
Miriam R Fernandes, John A McCulloch, Marco A Vianello, Quézia Moura, Paula J Pérez-Chaparro, Fernanda Esposito, Luciana Sartori, Milena Dropa, Maria H Matté, Débora P A Lira, Elsa M Mamizuka, Nilton Lincopan
A colistin-resistant Escherichia coli strain was recovered from a patient with a diabetic foot infection in Brazil. Whole-genome analysis revealed that the E. coli isolate belonged to the widespread sequence type (ST) 101 and harbored the mcr-1 gene on an IncX4 plasmid that was highly similar to mcr-1-bearing IncX4 plasmids that were recently identified in Enterobacteriaceae from food, animal, and human samples recovered on different continents. These results suggest that self-transmissible IncX4-type plasmids may represent promiscuous plasmids contributing to the intercontinental spread of the mcr-1 gene...
October 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27459019/clonal-transmission-of-gram-negative-bacteria-with-carbapenemases-ndm-1-vim-1-and-oxa-23-72-in-a-bulgarian-hospital
#12
Yvonne Pfeifer, Angelina Trifonova, Michael Pietsch, Magdalena Brunner, Iva Todorova, Ivanka Gergova, Gottfried Wilharm, Guido Werner, Encho Savov
We characterized 72 isolates with reduced susceptibility to carbapenems (50 Acinetobacter spp., 13 Proteus mirabilis, five Escherichia coli, one Morganella morganii, one Enterobacter cloacae, one Providencia rettgeri, and one Pseudomonas aeruginosa) from a hospital in Sofia, Bulgaria. Different β-lactamase genes were identified by polymerase chain reaction and sequencing. Bacterial strain typing was performed by enzymatic macrorestriction and pulsed-field gel electrophoresis (PFGE) typing as well as multilocus sequence typing for selected isolates...
April 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/27417195/diversity-of-escherichia-coli-strains-involved-in-vertebral-osteomyelitis-and-arthritis-in-broilers-in-brazil
#13
Juliana Fortes Vilarinho Braga, Nathalie Katy Chanteloup, Angélina Trotereau, Sylvie Baucheron, Rodrigo Guabiraba, Roselene Ecco, Catherine Schouler
BACKGROUND: Locomotor disorders and infections by Escherichia coli represent major concerns to the poultry industry worldwide. Avian pathogenic E. coli (APEC) is associated with extraintestinal infections leading to respiratory or systemic disease known as colibacillosis. The most common lesions seen in cases of colibacillosis are perihepatitis, airsacculitis, pericarditis, peritonitis/salpingitis and arthritis. These diseases are responsible for significant economic losses in the poultry industry worldwide...
July 14, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27324770/isolation-and-characterization-of-ndm-positive-escherichia-coli-from-municipal-wastewater-in-jeddah-saudi-arabia
#14
David Mantilla-Calderon, Muhammad Raihan Jumat, Tiannyu Wang, Pugalenthi Ganesan, Nada Al-Jassim, Pei-Ying Hong
The emergence of resistance to last-resort antibiotics is a public health concern of global scale. Besides direct person-to-person propagation, environmental pathways might contribute to the dissemination of antibiotic-resistant bacteria and antibiotic resistance genes (ARGs). Here, we describe the incidence of blaNDM-1, a gene conferring resistance to carbapenems, in the wastewater of the city of Jeddah, Saudi Arabia, over a 1-year period. blaNDM-1 was detected at concentrations ranging from 10(4) to 10(5) copies/m(3) of untreated wastewater during the entire monitoring period...
September 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27237423/multicentre-investigation-of-carbapenemase-producing-escherichia-coli-and-klebsiella-pneumoniae-in-german-hospitals
#15
MULTICENTER STUDY
Martin Kaase, Sven Schimanski, Reinhold Schiller, Bettina Beyreiß, Alexander Thürmer, Jörg Steinmann, Volkhard A Kempf, Christina Hess, Ingo Sobottka, Ines Fenner, Stefan Ziesing, Irene Burckhardt, Lutz von Müller, Axel Hamprecht, Ina Tammer, Nina Wantia, Karsten Becker, Thomas Holzmann, Martina Furitsch, Gabriele Volmer, Sören G Gatermann
Aim of this study was to determine the incidence and molecular epidemiology of carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in Germany. E. coli and K. pneumoniae isolates from clinical samples which were non-susceptible to carbapenems were collected in laboratories serving 20 hospitals throughout Germany from November 2013 to April 2014. The isolates were tested for the presence of carbapenemases by PCR and phenotypic methods and typed by multilocus sequence typing. Risk factors including a previous hospitalization abroad were analysed...
September 2016: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/26871556/characteristics-of-extended-spectrum-%C3%AE-lactamase-esbl-and-pampc-beta-lactamase-producing-enterobacteriaceae-of-water-samples-in-tunisia
#16
Leila Ben Said, Ahlem Jouini, Carla Andrea Alonso, Naouel Klibi, Raoudha Dziri, Abdellatif Boudabous, Karim Ben Slama, Carmen Torres
The presence of extended-spectrum beta-lactamase and plasmid-mediated AmpC beta-lactamase producing Enterobacteriaceae (ESBL-Eb and pAmpC-Eb, respectively) was analyzed in 57 wastewater and 57 surface-water samples in Tunisia. Twenty-four of the 57 wastewater samples (42.1%) and one of the 57 surface-water samples (1.7%, a river that received effluents of a wastewater-treatment-plant) contained ESBL-Eb or pAmpC-Eb; one ESBL/pAmpC-Eb per positive sample was further characterized. Beta-lactamase genes detected were as follows: blaCTX-M-1 (10 Escherichia coli),blaCTX-M-15 (eight E...
April 15, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/26739225/apramycin-treatment-affects-selection-and-spread-of-a-multidrug-resistant-escherichia-coli-strain-able-to-colonize-the-human-gut-in-the-intestinal-microbiota-of-pigs
#17
Ana Herrero-Fresno, Camilla Zachariasen, Monica Hegstad Hansen, Alexander Nielsen, Rene S Hendriksen, Søren Saxmose Nielsen, John Elmerdahl Olsen
The effect of apramycin treatment on transfer and selection of an Escherichia coli strain (E. coli 912) in the intestine of pigs was analyzed through an in vivo experiment. The strain was sequenced and assigned to the sequence type ST101 and serotype O11. It carried resistance genes to apramycin/gentamicin, sulphonamide, tetracycline, hygromycin B, β-lactams and streptomycin [aac(3)-IV, sul2, tet(X), aph(4), bla TEM-1 and strA/B], with all but tet(X) located on the same conjugative plasmid. Nineteen pigs were randomly allocated into two inoculation groups, one treated with apramycin (pen 2) and one non-treated (pen 3), along with a non-inoculated control group (pen 1)...
January 7, 2016: Veterinary Research
https://www.readbyqxmd.com/read/26552763/molecular-epidemiology-of-carbapenem-resistant-enterobacteriaceae-in-valle-d-aosta-region-italy-shows-the-emergence-of-kpc-2-producing-klebsiella-pneumoniae-clonal-complex-101-st101-and-st1789
#18
Mariateresa Del Franco, Laura Paone, Roberto Novati, Claudio G Giacomazzi, Maria Bagattini, Chiara Galotto, Pier Giorgio Montanera, Maria Triassi, Raffaele Zarrilli
BACKGROUND: The spread of carbapenem resistant Enterobacteriaceae (CRE) is an emerging clinical problem, of great relevance in Europe and worldwide. The aim of this study was the molecular epidemiology of CRE isolates in Valle d'Aosta region, Italy, and the mechanism of carbapenem resistance. RESULTS: Sixty consecutive CRE samples were isolated from 52 hospital inpatients and/or outpatients from November 2013 to August 2014. Genotyping of microbial isolates was done by pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST), carbapenemases were identified by PCR and sequencing...
2015: BMC Microbiology
https://www.readbyqxmd.com/read/26099612/prevalence-study-on-carbapenemase-producing-escherichia-coli-and-klebsiella-pneumoniae-isolates-in-czech-hospitals-results-from-czech-part-of-european-survey-on-carbapenemase-producing-enterobacteriaceae-euscape
#19
J Hrabák, V Študentová, V Jakubů, V Adámková, L Dvořáková, M Balejova, T Bergerová, E Chmelařová, P Ježek, P Kabelíková, M Kolář, P Paterová, R Tejkalová, C Papagiannitsis, H Žemličková
OBJECTIVE: One of the most important threats of current medicine is the spread of multiresistant Gram-negative bacteria. We report here data from a six-month prevalence study on carbapenemase-producing K. pneumoniae and E. coli performed in Czech hospitals participating on European Survey on Carbapenemase-Producing Enterobacteriaceae (EuSCAPE). METHODS: Ten hospitals covering all regions of the Czech Republic were selected. During the study period (1st November 2013 to 30th April 2014), first ten carbapenem non-susceptible isolates of K...
June 2015: Epidemiologie, Mikrobiologie, Imunologie
https://www.readbyqxmd.com/read/26001616/emergence-of-oxa-204-%C3%AE-lactamase-in-tunisia
#20
Karama Charfi, Wejdène Mansour, Anis Ben Haj Khalifa, Maha Mastouri, Mahjoub Aouni, Hedi Mammeri
A retrospective epidemiological survey was carried out to determine the prevalence of carbapenemase producers among enterobacterial clinical isolates recovered in the center of maternity and neonatology of Monastir (Tunisia). PCR screening identified 1 OXA-48 and 2 OXA-204 producers, which coexpressed the CTX-M-15 or the CMY-4 β-lactamases. PCR mapping showed that the bla(OXA-48) gene was carried by a Tn1999.2 transposon, whereas the bla(OXA-204) gene was part of the Tn2016 transposon-like structure. The OXA-48- or OXA-204-producing Klebsiella pneumoniae clinical isolates and the OXA-204-expressing Escherichia coli clinical isolate belonged to the widespread sequence types ST11, ST101, and ST617, respectively...
August 2015: Diagnostic Microbiology and Infectious Disease
keyword
keyword
29275
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"