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https://www.readbyqxmd.com/read/29679896/treatment-as-usual-tau-as-a-control-condition-in-trials-of-cognitive-behavioural-based-psychotherapy-for-self-harm-impact-of-content-and-quality-on-outcomes-in-a-systematic-review
#1
REVIEW
Katrina Witt, Daniela Pache de Moraes, Tatiana Taylor Salisbury, Ella Aren S Man, David Gunnell, Philip Hazell, Ellen Townsend, Kees van Heeringen, Keith Hawton
BACKGROUND: Randomized controlled trials (RCTs) are the mainstay of evaluations of the efficacy of psychosocial interventions. In a recent Cochrane systematic review we analysed the efficacy of cognitive behavioural-based psychotherapies compared to treatment as usual (TAU) in adults who self-harm. In this study we examine the content and reporting quality of TAU in these trials and their relationship to outcomes. METHODS: Five electronic databases (CCDANCTR-Studies and References, CENTRAL, MEDLINE, EMBASE, and PsycINFO) were searched for RCTs, indexed between 1 January 1998 and 30 April 2015, of cognitive-behavioural interventions compared to TAU for adults following a recent (within six months) episode of self-harm...
April 4, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29679849/global-analysis-of-advanced-metastatic-breast-cancer-decade-report-2005-2015
#2
Fatima Cardoso, Danielle Spence, Shirley Mertz, Dian Corneliussen-James, Kimberly Sabelko, Julie Gralow, Maria-João Cardoso, Fedro Peccatori, Diego Paonessa, Ann Benares, Naomi Sakurai, Marc Beishon, Sarah-Jane Barker, Musa Mayer
Approximately 0.5 million people worldwide die from metastatic breast cancer (mBC) every year. This manuscript provides an overview on the status of mBC in several regions of the world, highlighting the gaps in care, resources, and support available for patients with mBC. Primary research was conducted in 2015 and 2016, comprising four global qualitative and quantitative surveys of approximately 15,000 individuals in 34 countries. Secondary research was conducted using literature reviews of peer-reviewed publications, patient survey reports, and media or online articles...
April 18, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29679826/improving-the-organic-and-biological-fouling-resistance-and-removal-of-pharmaceutical-and-personal-care-products-through-nanofiltration-by-using-in-situ-radical-graft-polymerization
#3
Yi-Li Lin, Chia-Cheng Tsai, Nai-Yun Zheng
In this study, an insitu radical graft polarization technique using monomers of 3-sulfopropyl methacrylate potassium salt (SPM) and 2-hydroxyethyl methacrylate (HEMA) was applied to a commercial nanofiltration membrane (NF90) to improve its removal of six commonly detected pharmaceutical and personal care products (PPCPs) and mitigate organic and biological fouling by humic acid (HA) and sodium alginate (SA). Compared with the virgin membrane, the modified NF90 membrane exhibited considerably improved fouling resistance and an increased reversible fouling percentage, especially for SA+HA composite fouling Moreover, the PPCP removal of the modified NF90 membrane was higher than that of the virgin membrane after SA and SA+HA fouling, respectively...
April 17, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29679810/the-cost-effectiveness-of-seven-behavioural-interventions-to-prevent-drug-misuse-in-vulnerable-populations
#4
Becky Pennington, Brendan Collins, Simon Leigh, Antony P Martin, Lesley Owen, Alastair Fischer, Harry Sumnall, Geoff Bates
BACKGROUND: The National Institute for Health and Care Excellence (NICE) developed a guideline on drug misuse prevention in vulnerable populations. Part of the guideline development process involved evaluating cost-effectiveness and determining which interventions represented good value for money. METHODS: Economic models were developed for seven interventions which aimed to prevent drug use in vulnerable populations. The models compared the costs (to the health and crime sectors) and health benefits (in quality-adjusted life years (QALYs)) of each intervention and its comparator...
April 18, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29679397/development-of-tools-to-measure-dignity-for-older-people-in-acute-hospitals
#5
Marcelle Tauber-Gilmore, Christine Norton, Sue Procter, Trevor Murrells, Gulen Addis, Lesley Baillie, Pauline Velasco, Preet Athwal, Saeema Kayani, Zainab Zahran
BACKGROUND: Dignity is a concept that applies to all patients. Older patients can be particularly vulnerable to experiencing a loss of dignity in hospital. Previous tools developed to measure dignity have been aimed at palliative and end of life care. No tools for measuring dignity in acute hospital care have been reported. OBJECTIVES: To develop tools for measuring patient dignity in acute hospitals. SETTING: A large UK acute hospital. We purposively selected 17 wards where at least 50% of patients are 65 or over...
April 20, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29679362/anatomical-variation-in-the-form-of-inter-and-intra-individual-laterality-of-the-calcaneofibular-ligament
#6
Hisayoshi Yoshizuka, Kentaro Shibata, Toyoko Asami, Akio Kuraoka
The lateral ligament complex of the ankle is involved in a large proportion of ankle sprains. The calcaneofibular ligament (CFL) is often involved in severe injuries. The purpose of this study was to evaluate the anatomical variation and laterality of the CFL to improve our understanding of the mechanisms of CFL-related injuries. This study utilized 110 paired ankles from 55 formalin-fixed Japanese cadavers (33 male and 22 female). The length and width of the CFL and the angle created by the CFL and long axis of the fibula (CF angle) were measured after exposing the CFL by careful dissection from the surrounding tissues...
April 20, 2018: Anatomical Science International
https://www.readbyqxmd.com/read/29679317/sensitivity-analysis-for-not-at-random-missing-data-in-trial-based-cost-effectiveness-analysis-a-tutorial
#7
Baptiste Leurent, Manuel Gomes, Rita Faria, Stephen Morris, Richard Grieve, James R Carpenter
Cost-effectiveness analyses (CEA) of randomised controlled trials are a key source of information for health care decision makers. Missing data are, however, a common issue that can seriously undermine their validity. A major concern is that the chance of data being missing may be directly linked to the unobserved value itself [missing not at random (MNAR)]. For example, patients with poorer health may be less likely to complete quality-of-life questionnaires. However, the extent to which this occurs cannot be ascertained from the data at hand...
April 20, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29679216/hospital-based-psychosocial-support-program-for-children-with-all-and-their-families-a-comprehensive-triad-s-perspective
#8
Tanuja Kaushal, Sujata Satapathy, Rakesh Kumar Chadda, Sameer Bakhshi, Rajesh Sagar, Savita Sapra
OBJECTIVES: To elucidate potential target areas of intervention and mechanisms for implementation of intervention for children with cancer during the treatment phase. METHODS: Focused group discussion (FGDs) served as a primary source of providing phenomenal perspectives to explore the key objective. Eight focus groups of 45-60 min each were held with 5-9 members in each discussion. The participants were either patients, their caregivers or health care providers...
April 21, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29679187/growth-a-journey-from-experience-to-higher-perception-among-iranian-muslim-cpr-survivors
#9
Seyed Hamid Seyed Bagheri, Masoud Rayyani, Sedigheh Iranmanesh, Mahlagha Dehghan, Batool Tirgari, Seyed Habibollah Hosseini
Several studies have been conducted among cardiopulmonary resuscitation (CPR) survivors. Some studies have shown that positive and negative experiences coexist. Emotional distress and psychopathology in CPR survivors are related to the urgent need to make growth. Understanding the meaning of CPR survivors' lived experiences of growth may facilitate their growth. The aim of the study was to illuminate the meaning of CPR survivor's lived experiences of growth in southeast Iran. A qualitative design using a phenomenological hermeneutic approach influenced by Ricoeur was used in 12 CPR survivors...
April 20, 2018: Journal of Religion and Health
https://www.readbyqxmd.com/read/29679132/-self-reported-vision-in-gerontological-health-services-research-and-practice-an-opening-plea
#10
REVIEW
J Köberlein-Neu, A Seifert, I Himmelsbach
The use of self-reported vision is an integral part of most population surveys and is primarily used for healthcare monitoring. Since the patient's assessment is not always consistent with the objectively measured clinical parameters, the majority of the literature looks critically at the adequacy of self-reported vision, particularly with respect to answering epidemiological questions; however, it is often misunderstood that self-reported vision measures far more than the directly derived information show...
April 20, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29679128/-activities-without-patient-contact-estimate-of-time-costs-based-on-telephone-interviews-in-eight-psychiatric-hospitals
#11
A Blume, P Brückner-Bozetti, T Steinert
The aim of this pilot study was to estimate the share of working time that staff in psychiatric hospitals theoretically spend on obligatory activities, such as training and further education, organizational and documentation tasks as well as statutory lecturing duties without patient contact. A total of 47 physicians, 39 nurses, 34 psychologists and 35 social workers from eight psychiatric hospitals were interviewed. The results reveal that the theoretically remaining time for direct patient contact is low...
April 20, 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29679104/local-action-on-outdoor-air-pollution-to-improve-public-health
#12
REVIEW
Sotiris Vardoulakis, Rachel Kettle, Paul Cosford, Paul Lincoln, Stephen Holgate, Jonathan Grigg, Frank Kelly, David Pencheon
OBJECTIVES: The National Institute for Health and Care Excellence, jointly with Public Health England, have developed a guideline on outdoor air pollution and its links to health. The guideline makes recommendations on local interventions that can help improve air quality and prevent a range of adverse health outcomes associated with road-traffic-related air pollution. METHODS: The guideline was based on a rigorous assessment of the scientific evidence by an independent advisory committee, with input from public health professionals and other professional groups...
April 20, 2018: International Journal of Public Health
https://www.readbyqxmd.com/read/29679047/a-quality-improvement-initiative-to-reduce-necrotizing-enterocolitis-across-hospital-systems
#13
Amy T Nathan, Laura Ward, Kurt Schibler, Laurel Moyer, Andrew South, Heather C Kaplan
OBJECTIVE: Necrotizing enterocolitis (NEC) is a devastating intestinal disease in premature infants. Local rates of NEC were unacceptably high. We hypothesized that utilizing quality improvement methodology to standardize care and apply evidence-based practices would reduce our rate of NEC. STUDY DESIGN: A multidisciplinary team used the model for improvement to prioritize interventions. Three neonatal intensive care units (NICUs) developed a standardized feeding protocol for very low birth weight (VLBW) infants, and employed strategies to increase the use of human milk, maximize intestinal perfusion, and promote a healthy microbiome...
April 20, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29678995/intermittent-versus-continuous-oxygen-saturation-monitoring-for-infants-hospitalised-with-bronchiolitis-study-protocol-for-a-pragmatic-randomised-controlled-trial
#14
Sanjay Mahant, Gita Wahi, Lucy Giglia, Catherine Pound, Ronik Kanani, Ann Bayliss, Madan Roy, Mahmoud Sakran, Natascha Kozlowski, Karen Breen-Reid, Mollie Lavigne, Laila Premji, Myla E Moretti, Andrew R Willan, Suzanne Schuh, Patricia C Parkin
INTRODUCTION: Bronchiolitis is the most common reason for hospitalisation in infants in developed countries. The main focus of hospital care is on supportive care, such as monitoring for hypoxia and supplemental oxygen administration, as active therapies lack effectiveness. Pulse oximetry is used to monitor hypoxia in hospitalised infants and is used either intermittently or continuously. Observational studies have suggested that continuous pulse oximetry use leads to a longer length of hospital stay in stable infants...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678994/can-exercise-delay-transition-to-active-therapy-in-men-with-low-grade-prostate-cancer-a-multicentre-randomised-controlled-trial
#15
Daniel A Galvão, Dickon Hayne, Mark Frydenberg, Suzanne K Chambers, Dennis R Taaffe, Nigel Spry, Paul A Scuffham, Robert S Ware, Nicolas H Hart, Robert U Newton
INTRODUCTION: Active surveillance is a strategy for managing low-risk, localised prostate cancer, where men are observed with serial prostate-specific antigen assessments to identify signs of disease progression. Currently, there are no strategies to support active surveillance compliance nor are there interventions that can prevent or slow disease progression, ultimately delaying transition to active treatment before it is clinically required. Recently, we proposed that exercise may have a therapeutic potential in delaying the need for active treatment in men on active surveillance...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678992/clinicians-and-researchers-perspectives-on-establishing-and-implementing-core-outcomes-in-haemodialysis-semistructured-interview-study
#16
Allison Tong, Sally Crowe, John S Gill, Tess Harris, Brenda R Hemmelgarn, Braden Manns, Roberto Pecoits-Filho, Peter Tugwell, Wim van Biesen, Angela Yee Moon Wang, David C Wheeler, Wolfgang C Winkelmayer, Talia Gutman, Angela Ju, Emma O'Lone, Benedicte Sautenet, Andrea Viecelli, Jonathan C Craig
OBJECTIVES: To describe the perspectives of clinicians and researchers on identifying, establishing and implementing core outcomes in haemodialysis and their expected impact. DESIGN: Face-to-face, semistructured interviews; thematic analysis. STETTING: Twenty-seven centres across nine countries. PARTICIPANTS: Fifty-eight nephrologists (42 (72%) who were also triallists). RESULTS: We identified six themes: reflecting direct patient relevance and impact (survival as the primary goal of dialysis, enabling well-being and functioning, severe consequences of comorbidities and complications, indicators of treatment success, universal relevance, stakeholder consensus); amenable and responsive to interventions (realistic and possible to intervene on, differentiating between treatments); reflective of economic burden on healthcare; feasibility of implementation (clarity and consistency in definition, easily measurable, requiring minimal resources, creating a cultural shift, aversion to intensifying bureaucracy, allowing justifiable exceptions); authoritative inducement and directive (endorsement for legitimacy, necessity of buy-in from dialysis providers, incentivising uptake); instituting patient-centredness (explicitly addressing patient-important outcomes, reciprocating trial participation, improving comparability of interventions for decision-making, driving quality improvement and compelling a focus on quality of life)...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678970/feasibility-of-personalised-remote-long-term-follow-up-of-people-with-cochlear-implants-a-randomised-controlled-trial
#17
Helen Cullington, Padraig Kitterick, Mark Weal, Magdalena Margol-Gromada
INTRODUCTION: Substantial resources are required to provide lifelong postoperative care to people with cochlear implants. Most patients visit the clinic annually. We introduced a person-centred remote follow-up pathway, giving patients telemedicine tools to use at home so they would only visit the centre when intervention was required. OBJECTIVES: To assess the feasibility of comparing a remote care pathway with the standard pathway in adults using cochlear implants...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678967/development-and-evaluation-of-an-algorithm-based-tool-for-medication-management-in-nursing-homes-the-amber-study-protocol
#18
Susanne Erzkamp, Olaf Rose
BACKGROUND: Residents of nursing homes are susceptible to risks from medication. Medication Reviews (MR) can increase clinical outcomes and the quality of medication therapy. Limited resources and barriers between healthcare practitioners are potential obstructions to performing MR in nursing homes. Focusing on frequent and relevant problems can support pharmacists in the provision of pharmaceutical care services. This study aims to develop and evaluate an algorithm-based tool that facilitates the provision of Medication Management in clinical practice...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678962/open-label-cluster-randomised-controlled-trial-and-economic-evaluation-of-a-brief-letter-from-a-gp-on-unscheduled-medical-contacts-associated-with-the-start-of-the-school-year-the-pleasant-trial
#19
Steven A Julious, Michelle J Horspool, Sarah Davis, Matthew Franklin, W Henry Smithson, Paul Norman, Rebecca M Simpson, Heather Elphick, Oscar Bortolami, Cindy Cooper
BACKGROUND: Asthma is seasonal with peaks in exacerbation rates in school-age children associated with the return to school following the summer vacation. A drop in prescription collection in August is associated with an increase in the number of unscheduled contacts after the school return. OBJECTIVE: To assess whether a public health intervention delivered in general practice reduced unscheduled medical contacts in children with asthma. DESIGN: Cluster randomised trial with trial-based economic evaluation...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678945/ers-ecdc-statement-european-union-standards-for-tuberculosis-care-2017-update
#20
G B Migliori, G Sotgiu, S Rosales-Klintz, R Centis, L D'Ambrosio, I Abubakar, G Bothamley, J A Caminero, D M Cirillo, M Dara, G de Vries, S Aliberti, A T Dinh-Xuan, R Duarte, F Midulla, I Solovic, D Subotic, M Amicosante, A M Correira, A Cirule, G Gualano, H Kunst, F Palmieri, V Riekstina, S Tiberi, R Verduin, M J van der Werf
The International Standards for Tuberculosis (TB) Care define the essential level of care for managing patients who have or are presumed to have TB, or are at increased risk of developing the disease. The resources and capacity in the European Union and the European Economic Area (EU/EEA) permit higher standards of care to secure quality and timely TB diagnosis, prevention and treatment. On this basis, the European Union Standards for Tuberculosis Care (ESTC) were published in 2012 as standards specifically tailored to the EU-setting...
April 20, 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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