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https://www.readbyqxmd.com/read/28945016/cultural-hair-practices-physical-activity-and-obesity-among-urban-african-american-girls
#1
Felesia Bowen, Patricia O'Brien-Richardson
BACKGROUND AND PURPOSE: Hair holds cultural meaning and value for women of African descent. The values placed on hair type and hair style date back to preslavery days. There is a small body of literature that addresses the relationship between cultural hair practices and physical inactivity among black women. Understanding this is important because inactivity during childhood and adolescent years contributes to increased weight-related morbidity and mortality during adult years. The purpose of this study was to determine the relationship between cultural hair practices, physical activity, and obesity among urban African-American adolescent girls...
September 25, 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/28944991/a-qualitative-study-exploring-midwives-perceptions-and-knowledge-of-maternal-obesity-reflecting-on-their-experiences-of-providing-healthy-eating-and-weight-management-advice-to-pregnant-women
#2
Mary T McCann, Lisa Newson, Catriona Burden, Jane S Rooney, Margaret S Charnley, Julie C Abayomi
Midwives are responsible for providing advice regarding the complex issues of healthy eating and weight management during pregnancy. This study utilised an inductive data-driven thematic approach in order to determine midwives' perceptions, knowledge, and experiences of providing healthy eating and weight management advice to pregnant women. Semistructured interviews with 17 midwives were transcribed verbatim and data subjected to thematic analysis. The findings offer insight into the challenges facing midwives in their role trying to promote healthy eating and appropriate weight management to pregnant women...
September 25, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28944937/individual-development-and-potential-determinants-of-excess-weight-in-children-and-adolescents-a-longitudinal-study
#3
Alexandra Papandreou, Matthias Bopp, Julia Braun, Kaspar Staub, David Faeh
OBJECTIVES: Excess body weight is a major public health concern already at a young age. The aim of this study was to track weight status among pupils aged 6-14 years in the City of Zurich, to examine the association between sociodemographic and environmental factors and excess weight at school entry and excess weight gain thereafter. DESIGN: Longitudinal study. SETTING: Data were from the medical examinations routinely performed at public schools in Zurich, the largest city in Switzerland...
September 25, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28944882/evaluation-of-apoptosis-induced-by-exposure-to-antineoplastic-drugs-in-peripheral-blood-lymphocytes-of-nurses
#4
Heng Liao, Lijie Bi, Jun Wei, Xin Song
Cytostatic antineoplastic drugs are considered carcinogenic and mutagenic risk factors for health workers who are occupationally exposed to them; however, the molecular mechanisms underlying these effects remain to be elucidated. Therefore, the present study aimed to investigate the underlying mechanisms of antineoplastic drugs‑induced apoptosis of peripheral blood lymphocytes (PBLs) obtained from oncology nurses handling antineoplastic drugs. A microRNA (miRNA/miR) polymerase chain reaction (PCR) array was performed to analyze the expression levels of miRNAs in the PBLs from 3 trained nurses occupationally exposed to antineoplastic drugs...
September 22, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944880/edoxaban-improves-venous-thrombosis-via-increasing-hydrogen-sulfide-and-homocysteine-in-rat-model
#5
Wei Song, Hongbo Ci, Guanglei Tian, Yanjun Zhang, Xiaohu Ge
Anticoagulant therapy is prescribed to millions of patients worldwide for the prevention and treatment of venous thrombosis. Evidence has indicated that edoxaban is a potential drug of oral anticoagulant in the acute treatment of venous thromboembolism. Hydrogen sulfide and homocysteine plasma concentration are indicators of cardiovascular and neurovascular disease risk factors that have attracted considerable attention for regulation of vascular health and homeostasis. However, the molecular mechanism of edoxaban‑mediated differences of hydrogen sulfide and homocysteine has not been investigated in the progression of venous thrombosis...
September 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944855/integrated-mrnaseq-and-micrornaseq-data-analysis-for-grade%C3%A2-iii-gliomas
#6
Junqiang Dai, Zhitong Bing, Yinian Zhang, Qiao Li, Liang Niu, Wentao Liang, Guoqiang Yuan, Lei Duan, Hang Yin, Yawen Pan
The World Health Organization classification distinguishes four grades for gliomas. Grade III gliomas, which are brain malignant brain tumors with variable biological behavior and propensity, have been not widely investigated. The objective of the present study was to identify specific gene modules and valuable hubs associated with gliomagenesis and molecular signatures to assist in determining grade III glioma prognosis. mRNAseq and micro (mi)RNAseq data were used to construct a co‑expression network of gliomas using weight gene co‑expression network analysis, and revealed the prognostic molecular signature of grade III gliomas...
September 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944732/patient-centered-drug-approval-the-role-of-patient-advocacy-in-the-drug-approval-process
#7
T Joseph Mattingly, Linda Simoni-Wastila
Recent approval of eteplirsen for Duchenne muscular dystrophy (DMD), a rare disease with few treatment alternatives, has reignited the debate over the U.S. drug approval process. The evolution of legal and regulatory restrictions to the marketing and sale of pharmaceuticals has spanned more than a century, and throughout this history, patient advocacy has played a significant role. Scientific evidence from clinical trials serves as the foundation for drug approval, but the patient voice has become increasingly influential...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944731/the-fda-unapproved-drugs-initiative-an-observational-study-of-the-consequences-for-drug-prices-and-shortages-in-the-united-states
#8
Ravi Gupta, Sanket S Dhruva, Erin R Fox, Joseph S Ross
BACKGROUND: Hundreds of drug products are currently marketed in the United States without approval from the FDA. The 2006 Unapproved Drugs Initiative (UDI) requires manufacturers to remove these drug products from the market or obtain FDA approval by demonstrating evidence of safety and efficacy. Once the FDA acts against an unapproved drug, fewer manufacturers remain in the market, potentially enabling drug price increases and greater susceptibility to drug shortages. There is a need for systematic study of the UDI's effect on prices and shortages of all targeted drugs...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944730/optimization-of-medication-use-at-accountable-care-organizations
#9
Chrisanne Wilks, Erik Krisle, Kimberly Westrich, Kristina Lunner, David Muhlestein, Robert Dubois
BACKGROUND: Optimized medication use involves the effective use of medications for better outcomes, improved patient experience, and lower costs. Few studies systematically gather data on the actions accountable care organizations (ACOs) have taken to optimize medication use. OBJECTIVES: To (a) assess how ACOs optimize medication use; (b) establish an association between efforts to optimize medication use and achievement on financial and quality metrics; (c) identify organizational factors that correlate with optimized medication use; and (d) identify barriers to optimized medication use...
October 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28944716/breast-cancer-screening-among-women-in-namibia-explaining-the-effect-of-health-insurance-coverage-and-access-to-information-on-screening-behaviours
#10
Joseph Kangmennaang, Paul Mkandawire, Isaac Luginaah
OBJECTIVES: Breast cancer contributes substantially to morbidity and mortality in Namibia as is the case in most countries in Sub-Saharan Africa (SSA). However, there is a dearth of nationally representative studies that examine the odds of screening for breast cancer in Namibia and SSA at large. This paper aims to fill this gap by examining the determinants of breast cancer screening guided by the Health Belief Model. METHODS: We applied hierarchical binary logit regression models to explore the determinants of breast cancer screening using the 2013 Namibia Demography and Health Survey (NDHS)...
September 1, 2017: Global Health Promotion
https://www.readbyqxmd.com/read/28944609/hypertension-management-research-priorities-from-patients-caregivers-and-healthcare-providers-a-report-from-the-hypertension-canada-priority-setting-partnership-group
#11
Nadia Khan, Simon L Bacon, Samia Khan, Sara Perlmutter, Carline Gerlinsky, Mark Dermer, Lonni Johnson, Finderson Alves, Donna McLean, Andreas Laupacis, Mandy Pui, Angelique Berg, Felicia Flowitt
Patient- and stakeholder-oriented research is vital to improving the relevance of research. The authors aimed to identify the 10 most important research priorities of patients, caregivers, and healthcare providers (family physicians, nurses, nurse practitioners, pharmacists, and dietitians) for hypertension management. Using the James Lind Alliance approach, a national web-based survey asked patients, caregivers, and care providers to submit their unanswered questions on hypertension management. Questions already answered from randomized controlled trial evidence were removed...
September 25, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28944598/dentition-status-and-frailty-in-community-dwelling-older-adults-a-5-year-prospective-cohort-study
#12
Masanori Iwasaki, Akihiro Yoshihara, Misuzu Sato, Kumiko Minagawa, Mieko Shimada, Mamoru Nishimuta, Toshihiro Ansai, Yutaka Yoshitake, Hideo Miyazaki
AIM: To examine the longitudinal association between dentition status and incidence of frailty in older adults. METHODS: The present prospective cohort study included community-dwelling Japanese adults aged 75 years at baseline (n = 322). Dental examinations, biochemical blood examinations, physical performance and anthropometric measurements, and structured questionnaires were carried out at baseline. The presence of ≥20 teeth with nine or more occluding pairs of teeth was defined as functional dentition...
September 24, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28944459/the-changing-demographic-profile-of-dentists-and-dental-specialists-in-south-africa-2002-2015
#13
Ahmed Bhayat, Usuf Chikte
INTRODUCTION: It is essential to have regular audits of the number of oral health personnel so that planning, delivery of services and training can be addressed. There has not been such an audit in South Africa (SA) for more than 10 years. AIM: To determine the demographic profile of dentists and dental specialists (DS) between 2002 and 2015. METHODS: A retrospective record-based study was used and all dentists and DS registered with the Health Professions Council of South Africa (HPCSA) from 2002 till 2015 were included...
September 24, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28944447/serotonin-reuptake-inhibitors-and-mortality-in-epilepsy-a-linked-primary-care-cohort-study
#14
Colin B Josephson, Arturo Gonzalez-Izquierdo, Spiros Denaxas, Natalie K Fitzpatrick, Tolulope T Sajobi, Jordan D T Engbers, Scott Patten, Nathalie Jette, Samuel Wiebe
OBJECTIVE: Preliminary evidence suggests that serotonin reuptake inhibitor (SRI) use may increase postictal respiratory drive and prevent death. We sought to determine whether SRIs are associated with improved all-cause and possible seizure-specific mortality in patients with epilepsy. METHODS: Patients with epilepsy and a random 10:1 sample without epilepsy were extracted from The ClinicAl research using LInked Bespoke studies and Electronic health Records (CALIBER) resource...
September 24, 2017: Epilepsia
https://www.readbyqxmd.com/read/28944408/etiology-of-childhood-pneumonia-what-we-know-and-what-we-need-to-know-based-on-5th-dr-ic-verma-excellence-oration-award
#15
Joseph L Mathew
Childhood community acquired pneumonia continues to be an important clinical problem at the individual, institutional and community levels. Determination of microbial etiology is critical to develop evidence-based management (therapeutic and prophylactic) decisions. For decades, the approach to this relied on culture of lung aspirate specimens obtained from children with radiographically confirmed pneumonia, before administering antibiotics. Such studies revealed the major bacteria associated with pneumonia, prompting the World Health Organization to develop a highly sensitive clinical definition of pneumonia and advocate empiric antibiotic therapy; in order to save lives (focusing on community settings lacking resources for diagnostic tests)...
September 25, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28944283/how-does-legal-status-matter-for-oral-health-care-among-mexican-origin-children-in-california
#16
R S Oropesa, Nancy S Landale, Marianne M Hillemeier
This research examines the relationship between legal status and oral health care among Mexican-origin children. Using the 2001-2014 California Health Interview Surveys, the objectives are: (1) to demonstrate population-level changes in the legal statuses of parents, the legal statuses of children, and the likelihood of receiving dental care; (2) to reveal how the roles of legal status boundaries in dental care are changing; and (3) to determine whether the salience of these boundaries is attributable to legal status per se...
December 2017: SSM—Population Health
https://www.readbyqxmd.com/read/28943983/the-impact-of-drug-related-problems-on-health-related-quality-of-life-among-hypertensive-patients-in-jordan
#17
Rana Abu Farha, Akram Saleh, Salah Aburuz
BACKGROUND: Hypertension is a major cause of cardiovascular diseases with a high prevalence in Jordan. No previous studies have been carried out to determine the effect of the presence of drug-related problems (DRPs) on the health-related quality of life (HRQOL) among hypertensive patients. OBJECTIVES: The purpose of this study was to identify the influence of different types of DRPs on the HRQOL of hypertensive patients. METHODS: A total of 200 hypertensive patients were recruited in this cross-sectional correlation study that was conducted across the cardiac outpatient clinic at Jordan University Hospital...
July 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28943861/a-practical-and-time-efficient-high-intensity-interval-training-program-modifies-cardio-metabolic-risk-factors-in-adults-with-risk-factors-for-type-ii-diabetes
#18
Bethan E Phillips, Benjamin M Kelly, Mats Lilja, Jesús Gustavo Ponce-González, Robert J Brogan, David L Morris, Thomas Gustafsson, William E Kraus, Philip J Atherton, Niels B J Vollaard, Olav Rooyackers, James A Timmons
INTRODUCTION: Regular physical activity (PA) can reduce the risk of developing type 2 diabetes, but adherence to time-orientated (150 min week(-1) or more) PA guidelines is very poor. A practical and time-efficient PA regime that was equally efficacious at controlling risk factors for cardio-metabolic disease is one solution to this problem. Herein, we evaluate a new time-efficient and genuinely practical high-intensity interval training (HIT) protocol in men and women with pre-existing risk factors for type 2 diabetes...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/28943830/the-clinical-implications-of-youth-sports-concussion-laws-a-review
#19
Jeneita M Bell, Christina L Master, Michael R Lionbarger
The recent passage of state youth sports concussion laws across the country introduces clinical implications for health care professionals caring for student-athletes. Although the laws were established to provide protections for student-athletes and prevent adverse outcomes, efforts aimed at implementation have uncovered various challenges in concussion diagnosis and management. Some of the most salient issues include medical evaluation, return to play, and return to learn. For this reason, health care professionals play a pivotal role in determining the critical next steps after a student is removed from play with a suspected concussion...
2017: American Journal of Lifestyle Medicine
https://www.readbyqxmd.com/read/28943825/can-a-short-video-improve-inhaler-use-in-urban-youth
#20
Sara Brown, Victoria Tutag Lehr, Nathan French, Christopher Alan Giuliano
OBJECTIVE: The primary aim was to determine whether watching a short video in the inpatient setting could produce an immediate improvement in pediatric patients' asthma knowledge and inhaler technique. METHODS: This prospective, quasi-experimental, pre-post study was conducted in a single center, in Detroit, Michigan, which primarily serves an urban, African-American population. Patients were eligible if they were between 8- and 16-years-old, had asthma, and would be discharged with an albuterol metered-dose inhaler...
July 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
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