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https://www.readbyqxmd.com/read/29681247/food-choices-and-distress-in-reservation-based-american-indians-and-alaska-natives-with-type-2-diabetes
#1
Nicolette I Teufel-Shone, Luohua Jiang, Jennifer Rockell, Jennifer Chang, Janette Beals, Ann Bullock, Spero M Manson
OBJECTIVE: To examine the association between food choice and distress in a large national sample of American Indians/Alaska Natives (AI/AN) with type 2 diabetes. DESIGN: Participants completed a sociodemographic survey, an FFQ and the Kessler-6 Distress Scale. Foods were identified as 'healthy' or 'unhealthy' using a classification grounded in the health education provided by the programme case managers; healthy and unhealthy food scores were calculated using reported intake frequencies...
April 23, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29681171/economic-value-of-improved-accuracy-for-self-monitoring-of-blood-glucose-devices-for-type-1-and-type-2-diabetes-in-england
#2
Robert Brett McQueen, Marc D Breton, Joyce Craig, Hayden Holmes, Melanie D Whittington, Markus A Ott, Jonathan D Campbell
OBJECTIVE: The objective was to model clinical and economic outcomes of self-monitoring blood glucose (SMBG) devices with varying error ranges and strip prices for type 1 and insulin-treated type 2 diabetes patients in England. METHODS: We programmed a simulation model that included separate risk and complication estimates by type of diabetes and evidence from in silico modeling validated by the Food and Drug Administration. Changes in SMBG error were associated with changes in hemoglobin A1c (HbA1c) and separately, changes in hypoglycemia...
April 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29681170/perceptions-of-family-among-low-income-patients-with-diabetes-in-a-text-based-mobile-health-intervention
#3
Elizabeth R E Burner, Michael D Menchine, Katrina Kubicek, Marisela Robles, Marjorie Kagawa Singer, Sanjay Arora
BACKGROUND: Diabetes disproportionately affects the US Latino population, due to socioeconomic pressures, genetics, reduced access to care and cultural practices. While efforts to improve self-care through interventions incorporating family are highly rated by Latinos, family can be both supportive and obstructive. To develop effective interventions, this role needs clarification. METHODS: We conducted group interviews in Spanish and English with 24 participants with diabetes from a mobile health diabetes self-care intervention...
April 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29679632/dietary-habits-associated-with-reduced-insulin-resistance-the-nagahama-study
#4
Kaori Ikeda, Tosiya Sato, Takeo Nakayama, Daisuke Tanaka, Kazuaki Nagashima, Fumika Mano, Erina Joo, Shimpei Fujimoto, Yoshimitsu Takahashi, Shinji Kosugi, Akihiro Sekine, Yasuharu Tabara, Fumihiko Matsuda, Nobuya Inagaki
AIMS: To investigate the association between insulin resistance assessed by a homeostasis model and dietary habits. METHODS: Cross-sectional analysis using a community-based cohort, the Nagahama Prospective Cohort for Comprehensive Human Bioscience. Multiple linear regression analysis was performed with log HOMA-IR or log HOMA- β as the dependent variable and 20 dietary habits, tobacco smoking, medical history, family medical history of diabetes, age and BMI as the simultaneous independent variables in each sex separately...
April 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29679625/nutrition-therapy-within-and-beyond-gestational-diabetes
#5
REVIEW
Teri L Hernandez, Archana Mande, Linda A Barbour
With the global rising prevalence of gestational diabetes (GDM), an adaptable, economical approach to nutrition therapy that effectively controls maternal glycemia while promoting normal fetal growth will have far-reaching implications. The conventional focus has been to rigidly limit all types of carbohydrate. While controlling glucose, this approach fosters maternal anxiety and is a primary barrier to adherence. Many mothers substitute fat for carbohydrate, which may unintentionally enhance lipolysis, promote elevated free fatty acids (FFA), and worsen maternal insulin resistance (IR)...
April 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29679277/the-role-of-mitochondrial-dna-damage-at-skeletal-muscle-oxidative-stress-on-the-development-of-type-2-diabetes
#6
Julia Matzenbacher Dos Santos, Denise Silva de Oliveira, Marcos Lazaro Moreli, Sandra Aparecida Benite-Ribeiro
Reduced cellular response to insulin in skeletal muscle is one of the major components of the development of type 2 diabetes (T2D). Mitochondrial dysfunction involves in the accumulation of toxic reactive oxygen species (ROS) that leads to insulin resistance. The aim of this study was to verify the involvement of mitochondrial DNA damage at ROS generation in skeletal muscle during development of T2D. Wistar rats were fed a diet containing 60% fat over 8 weeks and at day 14 a single injection of STZ (25 mg/kg) was administered (T2D-induced)...
April 20, 2018: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/29678976/fostering-active-living-and-healthy-eating-through-understanding-physical-activity-and-dietary-behaviours-of-arabic-speaking-adults-a-cross-sectional-study-from-the-middle-east
#7
Tam Truong Donnelly, Tak Shing Fung, Al-Anoud Bint Mohammad Al-Thani
OBJECTIVES: Physical inactivity and unhealthy diets increase the risk for diabetes, cardiovascular diseases and cancer. Many people in Qatar are sedentary and consume diets high in fats, salt and sugar. The purpose of this study was to determine physical activity levels, food habits and understand the variables that might predict physical activity and healthy eating behaviours among Arabic-speaking adults living in the State of Qatar. SETTING: A cross-sectional community-based survey was conducted with 1606 Arab adults ≥18 years of age from March 2013 to June 2015...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678652/octogenarians-undergoing-open-repair-have-higher-mortality-compared-to-fenestrated-endovascular-repair-of-intact-abdominal-aortic-aneurysms-involving-the-visceral-vessels
#8
Satinderjit Locham, Muhammad Faateh, Hanaa Dakour Aridi, Besma Nejim, Mahmoud Malas
BACKGROUND: Prior studies have shown that octogenarians have a higher risk of mortality compared to non-octogenarians undergoing open (OAR) and endovascular (EVAR) abdominal aortic aneurysm (AAA) repair. Fenestrated-endovascular repair (F-EVAR) was approved by Food and Drug Administration (FDA) in 2012 and has been populated as a less invasive approach to treat patients with suboptimal neck anatomy with favorable outcomes compared to traditional OAR. The aim of the study is to compare 30-day outcomes of F-EVAR vs...
April 17, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29677556/prenatal-exposure-to-polychlorinated-biphenyls-and-fetal-growth-in-british-girls
#9
Jill F Patel, Terryl J Hartman, Andreas Sjodin, Kate Northstone, Ethel V Taylor
Polychlorinated biphenyls (PCBs) are synthetic chemicals that bioaccumulate in the food chain. PCBs were used primarily for industrial applications due to their insulating and fire retardant properties, but were banned in the 1970s in the United States and in the 1980s in the United Kingdom, as adverse health effects following exposure were identified. Previous studies of populations with high PCB exposure have reported inverse associations with birth weight and gestational length. Birth weight is a powerful predictor of infant survival, and low birth weight can predispose infants to chronic conditions in adult life such as diabetes and cardiovascular diseases...
April 17, 2018: Environment International
https://www.readbyqxmd.com/read/29671076/sugar-sweetened-beverage-obesity-and-type-2-diabetes-in-children-and-adolescents-policies-taxation-and-programs
#10
REVIEW
Yilin Yoshida, Eduardo J Simoes
PURPOSE OF REVIEW: Obesity has grown at an alarming rate in children and adolescents. Concurrently, consumption on sugar-sweetened beverages (SSBs) also rose significantly. This review provides an overview of obesity and type 2 diabetes mellitus (T2DM) related to SSBs and current policies restricting SSBs in schools, school-based interventions, and taxation on reducing SSB intake and obesity. We also discuss challenges of and future steps for these initiatives. RECENT FINDINGS: Clinical and epidemiological studies suggest a strong association between SSB intake and obesity and T2DM...
April 18, 2018: Current Diabetes Reports
https://www.readbyqxmd.com/read/29670913/vegetarian-diet-and-cardiometabolic-risk-among-asian-indians-in-the-united-states
#11
Ranjita Misra, Padmini Balagopal, Sudha Raj, Thakor G Patel
Research studies have shown that plant-based diets confer cardiovascular and metabolic health benefits. Asian Indians (AIs) in the US (who have often followed plant-based diets) have elevated risk for chronic diseases such as diabetes, metabolic syndrome, and obesity suggesting ethnic vulnerability that imply genetic and/or lifestyle causative links. This study explored the association between this ethnic group and diabetes, obesity, and metabolic syndrome after controlling for demographics, acculturation, family history of diabetes, and lifestyle and clinical risk factors...
2018: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29670663/the-effect-of-sanggua-drink-extract-on-insulin-resistance-through-the-pi3k-akt-signaling-pathway
#12
Yu Cai, Ying Wang, Fei Zhi, Qi-Chang Xing, Yun-Zhong Chen
Treating type 2 diabetes mellitus (T2DM) using thiazolidinediones and biguanides can present several challenges for patients. Sanggua Drink (SGD) is a commonly used agent in traditional Chinese medicine, and it consists of Folium Mori , Fructus Momordicae Charantiae , Radix Puerariae Lobatae , and Rhizoma Dioscorea . The hypoglycemic effects and mechanisms of SGD extracts on insulin resistance in diabetic rats were investigated. SGD (1.24 g/kg orally) was verified in T2DM rats induced by a high-fat diet and streptozotocin...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29670040/pectin-and-pectin-based-composite-materials-beyond-food-texture
#13
REVIEW
Claudia Lara-Espinoza, Elizabeth Carvajal-Millán, René Balandrán-Quintana, Yolanda López-Franco, Agustín Rascón-Chu
Pectins are plant cell wall natural heteropolysaccharides composed mainly of α-1-4 d-galacturonic acid units, which may or may not be methyl esterified, possesses neutral sugars branching that harbor functional moieties. Physicochemical features as pH, temperature, ions concentration, and cosolute presence, affect directly the extraction yield and gelling capacity of pectins. The chemical and structural features of this polysaccharide enables its interaction with a wide range of molecules, a property that scientists profit from to form new composite matrices for target/controlled delivery of therapeutic molecules, genes or cells...
April 18, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29668697/efficacy-and-safety-of-biosimilar-insulins-compared-to-their-reference-products-a-systematic-review
#14
Carolyn Tieu, Eleanor J Lucas, Mindi DePaola, Lori Rosman, G Caleb Alexander
IMPORTANCE: For nearly a century, no generic form of insulin has been available in the United States. However, the first biosimilar insulin, Basaglar, was approved by the U.S. Food and Drug Administration in 2015, and subsequently Admelog and Lusduna in 2017. OBJECTIVE: To summarize the scientific evidence comparing the safety, efficacy, pharmacokinetics, and pharmacodynamics of biosimilar and reference insulin products. DATA SOURCES: We conducted a systematic review using PubMed, Cochrane, Embase, Latin America and Caribbean Health Sciences, South Asian Database of Controlled Clinical Trials, and IndiaMED from their inception through January 14, 2018...
2018: PloS One
https://www.readbyqxmd.com/read/29668313/dietary-glycemic-load-glycemic-index-and-carbohydrate-intake-on-the-risk-of-lung-cancer-among-men-and-women-in-shanghai
#15
Jiang-Wei Sun, Wei Zheng, Hong-Lan Li, Jing Gao, Gong Yang, Yu-Tang Gao, Nat Rothman, Qing Lan, Xiao-Ou Shu, Yong-Bing Xiang
To investigate the potential influence of dietary glycemic index, glycemic load, or carbohydrate intake and lung cancer risk in Shanghai. We prospectively investigated the associations among 130,858 participants in the Shanghai Women's and Men's Health Studies. Diet was assessed using validated food-frequency questionnaires. Lung cancer cases were ascertained through annual record linkage and every 2-3 years in-home visits. Cox proportional hazard regression model was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs)...
April 18, 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29668036/optimization-of-extraction-of-hypoglycemic-ingredients-from-grape-seeds-and-evaluation-of-%C3%AE-glucosidase-and-%C3%AE-amylase-inhibitory-effects-in-vitro
#16
Fansheng Kong, Yaru Qin, Zhipeng Su, Zhengxiang Ning, Shujuan Yu
Grape seeds full with oil and also rich in hypoglycemic ingredients. This study is to improve the comprehensive utilization of grape seeds and the quality of grape seeds oil. Extract water soluble active substances before extracting oil from grape seeds, which show the grape seeds in water soluble extracts containing TP, TC, PC contents, respectively, are 171.1 ± 1.1, 658.8 ± 0.2, 482.3 ± 0.2 (mg GSAE/g). Also we found GSAE samples containing catechin and epicatechin were 44.12 ± 0.21 mg/mL, 111.23 ± 1...
April 18, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29667406/identification-of-novel-bioactive-peptides-with-%C3%AE-amylase-inhibitory-potential-from-enzymatic-protein-hydrolysates-of-red-seaweed-porphyra-spp
#17
Habtamu Admassu, Mohammed A A Gasmalla, Ruijin Yang, Wei Zhao
Inhibition of α-amylase enzyme is one therapeutic approach in lowering glucose level in the blood to manage diabetes mellitus. In this study α-amylase inhibitory peptides were identified from proteolytic enzymes hydrolysates of red seaweed laver (Porphyra species) using consecutive chromatographic techniques. In the resultant fractions from RP-HPLC (D1-10), D2 inhibited α-amylase activity (88.67 ± 1.05 %) significantly (p ≤ 0.5) at 1mg/mL protein concentration. A mass spectrometry (ESI-Q-TOF- MS) analysis was used to identify peptides from this fraction...
April 18, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29663292/the-potential-role-of-sglt2-inhibitors-in-the-treatment-of-type-1-diabetes-mellitus
#18
Hadi Fattah, Volker Vallon
Type 1 diabetes mellitus is a difficult disease to treat due to the relative paucity of therapeutic options other than injectable insulin. The latter, however, can induce hypoglycemia, which has been linked to enhanced cardiovascular risk. Sodium glucose cotransporter 2 (SGLT2) inhibitors are a new class of oral anti-hyperglycemic medications that do not increase the hypoglycemia risk and are US Food and Drug Administration (FDA) approved in type 2 diabetes mellitus. SGLT2 inhibitors may also be of benefit in type 1 diabetic patients, in addition to insulin, although they have not yet been approved for this indication...
April 16, 2018: Drugs
https://www.readbyqxmd.com/read/29662204/feeding-circuit-development-and-early-life-influences-on-future-feeding-behaviour
#19
REVIEW
Lori M Zeltser
A wide range of maternal exposures - undernutrition, obesity, diabetes, stress and infection - are associated with an increased risk of metabolic disease in offspring. Developmental influences can cause persistent structural changes in hypothalamic circuits regulating food intake in the service of energy balance. The physiological relevance of these alterations has been called into question because maternal impacts on daily caloric intake do not persist to adulthood. Recent behavioural and epidemiological studies in humans provide evidence that the relative contribution of appetitive traits related to satiety, reward and the emotional aspects of food intake regulation changes across the lifespan...
April 17, 2018: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/29662128/the-extracellular-domain-of-staphylococcus-aureus-ltas-binds-insulin-and-induces-insulin-resistance-during-infection
#20
Yu Liu, Fang-Jie Liu, Zhang-Chun Guan, Fang-Ting Dong, Jian-Hua Cheng, Ya-Ping Gao, Di Li, Jun Yan, Cheng-Hua Liu, Dian-Peng Han, Chun-Mei Ma, Jian-Nan Feng, Bei-Fen Shen, Guang Yang
Insulin resistance is a risk factor for obesity and diabetes and predisposes individuals to Staphylococcus aureus colonization; however, the contribution of S. aureus to insulin resistance remains unclear. Here, we show that S. aureus infection causes impaired glucose tolerance via secretion of an insulin-binding protein extracellular domain of LtaS, eLtaS, which blocks insulin-mediated glucose uptake. Notably, eLtaS transgenic mice (eLtaS trans ) exhibited a metabolic syndrome similar to that observed in patients, including increased food and water consumption, impaired glucose tolerance and decreased hepatic glycogen synthesis...
April 16, 2018: Nature Microbiology
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