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https://www.readbyqxmd.com/read/27916114/competitive-inhibition-assay-for-the-detection-of-progesterone-in-dairy-milk-using-a-fiber-optic-spr-biosensor
#1
D Daems, J Lu, F Delport, N Mariën, L Orbie, B Aernouts, I Adriaens, T Huybrechts, W Saeys, D Spasic, J Lammertyn
Analytical methods that are often used for the quantification of progesterone in bovine milk include immunoassays and chromatographic techniques. Depending on the selected method, the main disadvantages are the cost, time-to-result, labor intensity and usability as an automated at-line device. This paper reports for the first time on a robust and practical method to quantify small molecules, such as progesterone, in complex biological samples using an automated fiber optic surface plasmon resonance (FO-SPR) biosensor...
January 15, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/27908873/the-bmj-christmas-appeal-2016-7-orbis-the-sight-savers
#2
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27894229/-self-reported-experience-in-patients-treated-with-hepatitis-c-direct-acting-antivirals
#3
Irene Cañamares Orbis, Javier Saez de la Fuente, Ismael Escobar Rodriguez, Concepción Esteban Alba, Ana Such Díaz, Ismael Escobar Rodríguez
BACKGROUND AND OBJECTIVE: To learn about and analyze the self-reported treatment experience of HCV patients who started treatment with direct acting antivirals agents (DAA), at a real-time, proactive and integrated into the pharmaceutical care healthcare process, using a prospective questionnaire completed by patients as clinical tool. MATERIAL AND METHODS: Observational and cross-sectional study conducted between April (start of the National Strategic Plan) and December 2015 in the Outpatient Pharmacy Service...
November 1, 2016: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/27894226/adaptation-of-oral-medication-in-people-institutionalized-in-nursing-homes-for-whom-medication-is-crushed-the-adecua-study
#4
Francisco Apolo Carvajal, María González Martínez, Elena Capilla Santamaría, Betsabé Cáliz Hernández, Icíar Cañamares Orbis, Nuria Martínez Casanova, Eugenia Martínez Sánchez, Ainhoa Aranguren Oyarzábal, María José Calvo Alcántara, Encarnación Cruz Martos
PURPOSE: To evaluate the effect of pharmacist interventions in the adaptation of pharmaceutical forms in elders institutionalized in nursing homes whose medicines are crushed, which may have a clinical relevance. METHODS: Quasi-experimental, multicenter, transversal and prospective study carried out in 10 nursing homes. Subjects for whom drugs were being crushed were identified. Their treatments were reviewed in order to identify drugs that should not be crushed...
November 1, 2016: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/27818120/efficacy-and-safety-of-prehospital-administration-of-unfractionated-heparin-enoxaparin-or-bivalirudin-in-patients-undergoing-primary-percutaneous-coronary-intervention-for-st-segment-elevation-myocardial-infarction-insights-from-the-orbi-registry
#5
Vincent Auffret, Guillaume Leurent, Dominique Boulmier, Marc Bedossa, Amer Zabalawi, Jean-Philippe Hacot, Isabelle Coudert, Emmanuelle Filippi, Philippe Castellant, Antoine Rialan, Gilles Rouault, Philippe Druelles, Bertrand Boulanger, Josiane Treuil, Bertrand Avez, Marielle Le Guellec, Martine Gilard, Hervé Le Breton
BACKGROUND: Despite numerous studies in recent years, the best anticoagulant option for primary percutaneous coronary intervention (PCI) remains a matter of debate. AIMS: To compare in-hospital outcomes after prehospital administration of low-dose unfractionated heparin (UFH)±glycoprotein IIb/IIIa inhibitors (GPIs), enoxaparin±GPIs, or bivalirudin in patients undergoing primary PCI for ST-segment elevation myocardial infarction (STEMI). METHODS: A total of 1720 patients (median age 62...
November 3, 2016: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/27401364/a-protocol-for-a-randomised-controlled-trial-investigating-the-effect-of-increasing-omega-3-index-with-krill-oil-supplementation-on-learning-cognition-behaviour-and-visual-processing-in-typically-developing-adolescents
#6
I S M van der Wurff, C von Schacky, K Berge, P A Kirschner, R H M de Groot
INTRODUCTION: The influence of n-3 long-chain polyunsaturated fatty acids (LCPUFA) supplementation on brain functioning is debated. Some studies have found positive effects on cognition in children with learning difficulties, elderly people with cognitive impairment and depression scores in depressed individuals. Other studies have found null or negative effects. Observational studies in adolescents have found positive associations between fish consumption (containing n-3 LCPUFAs) and academic achievement...
July 8, 2016: BMJ Open
https://www.readbyqxmd.com/read/27395538/g-j-billberg-s-1833-on-the-ichthyology-and-description-of-some-new-fish-species-of-the-pipefish-genus-syngnathus
#7
Sven O Kullander
Gustaf Johan Billberg's review of ichthyology, published in Swedish in 1833 in the Linnéska samfundets handlingar, mentions 92 fish taxa at genus and species level, 41 of which represent new taxa, unnecessary replacement names, or unjustified emendations. Billberg presents his own classification of fishes, in which five new family names are introduced: Ballistidae, Diodontidae, Ooididae, Chironectidae, and Macrorhyncidae. Diodontidae has priority over Diodontidae Bonaparte, 1835. Macrorhyncidae was published earlier than Gempylidae Gill, 1862, but the latter has priority by prevailing usage...
2016: Zootaxa
https://www.readbyqxmd.com/read/27381527/type-4-duane-syndrome
#8
Joshua A Schliesser, Derek T Sprunger, Eugene M Helveston
PURPOSE: To identify cases of synergistic divergence whose characteristics suggest that this entity is a form of Duane syndrome. METHODS: The records of all patients with a Duane syndrome diagnosis, including standardized eye position photographs, from the E-Consultation program of Cybersight, Orbis International were analyzed. RESULTS: A total of 350 Duane syndrome cases were identified. Of these, 19 (5%) had features consistent with synergistic divergence, or type 4 Duane syndrome...
August 2016: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/27371950/cross-cultural-adaptation-and-validation-of-the-medication-regimen-complexity-index-adapted-to-spanish
#9
Javier Saez de la Fuente, Ana Such Diaz, Irene Cañamares-Orbis, Estela Ramila, Elsa Izquierdo-Garcia, Concepcion Esteban, Ismael Escobar-Rodríguez
BACKGROUND: The most widely used validated instrument to assess the complexity of medication regimens is the Medication Regimen Complexity Index (MRCI). OBJECTIVE: This study aimed to translate, adapt, and validate a reliable version of the MRCI adapted to Spanish (MRCI-E). METHODS: The cross-cultural adaptation process consisted of an independent translation by 3 clinical pharmacists and a backtranslation by 2 native English speakers. A reliability analysis was conducted on 20 elderly randomly selected patients...
July 2, 2016: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/27054621/does-staff-see-what-experts-see-accuracy-of-front-line-staff-in-scoring-juveniles-risk-factors
#10
Patrick J Kennealy, Jennifer L Skeem, Isaias R Hernandez
Although increasingly complex risk assessment tools are being marketed, little is known about "real world" practitioners' capacity to score them accurately. In this study, we assess the extent to which 78 staff members' scoring of juveniles on the California-Youth Assessment and Screening Instrument (CA-YASI; Orbis Partners, Inc., 2008) agree with experts' criterion scores for those cases. There are 3 key findings. First, at the total score level, practitioners manifest limited agreement (M ICC = .63) with the criterion: Only 59...
April 7, 2016: Psychological Assessment
https://www.readbyqxmd.com/read/27005603/structure-solubility-and-stability-of-orbifloxacin-crystal-forms-hemihydrate-versus-anhydrate
#11
Olimpia Maria Martins Santos, Jennifer Tavares Jacon Freitas, Edith Cristina Laignier Cazedey, Magali Benjamim de Araújo, Antonio Carlos Doriguetto
Orbifloxacin (ORBI) is a widely used antimicrobial drug of the fluoroquinolone class. In the official pharmaceutical compendia the existence of polymorphism in this active pharmaceutical ingredient (API) is reported. No crystal structure has been reported for this API and as described in the literature, its solubility is very controversial. Considering that different solid forms of the same API may have different physicochemical properties, these different solubilities may have resulted from analyses inadvertently carried out on different polymorphs...
2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/26780606/a-study-of-the-complexation-of-mercury-ii-with-dicysteinyl-tetrapeptides-by-electrospray-ionization-mass-spectrometry
#12
Johanna Mazlo, Maria Ngu-Schwemlein
In this study we evaluated a method for the characterization of complexes, formed in different relative ratios of mercury(II) to dicysteinyl tetrapeptide, by electrospray ionization orbitrap mass spectrometry. This strategy is based on previous successful characterization of mercury-dicysteinyl complexes involving tripeptides by utilizing mass spectrometry among other techniques. Mercury(II) chloride and a dicysteinyl tetrapeptide were incubated in a degassed buffered medium at varying stoichiometric ratios...
January 8, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/26746040/inter-observer-reliability-of-measurements-performed-on-digital-long-leg-standing-radiographs-and-assessment-of-validity-compared-to-3d-ct-scan
#13
B Boonen, B Kerens, M G M Schotanus, P Emans, B Jong, N P Kort
BACKGROUND: Long-leg radiographs (LLR) are often used in orthopaedics to assess limb alignment in patients undergoing total knee arthroplasty (TKA). However, there are still concerns about the adequacy of measurements performed on LLR. We assessed the reliability and validity of measurements on LLR using three-dimensional computed tomography (3D CT)-scan as a gold standard. METHODS: Six different surgeons measured the mechanical axis and position of the femoral and tibial components individually on 24 LLR...
January 2016: Knee
https://www.readbyqxmd.com/read/26730509/serum-metabolomics-study-of-traditional-chinese-medicine-formula-intervention-to-polycystic-ovary-syndrome
#14
Caixia Lu, Xinjie Zhao, Yan Li, Yanjie Li, Chengkun Yuan, Fang Xu, Xiaoyu Meng, Lihui Hou, Guowang Xu
Polycystic ovary syndrome (PCOS) is a most common, heterogeneous, complex endocrinopathy disease. Traditional Chinese medicine (TCM) has been used in the treatment of PCOS for many years. However, the mechanism underlying TCM remains obscure and challenging. In this study, 30 PCOS subjects were separated into normoinsulinemic group (NI=13) and hyperinsulinemic group (HI=17), and treated for three menstrual cycles with TCM Formula, Bushen Huatan Formula (BHF). A metabolomics approach based on ultra-high-performance liquid chromatography (UPLC) coupled with linear ion trap Orbi-trap mass spectrometer (LTQ Orbi-trap MS) is used to investigate serum metabolic changes of TCM intervention to PCOS...
February 20, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/26660871/high-degree-atrioventricular-block-complicating-st-segment-elevation-myocardial-infarction-in-the-contemporary-era
#15
Vincent Auffret, Aurélie Loirat, Guillaume Leurent, Raphael P Martins, Emmanuelle Filippi, Isabelle Coudert, Jean Philippe Hacot, Martine Gilard, Philippe Castellant, Antoine Rialan, Régis Delaunay, Gilles Rouault, Philippe Druelles, Bertrand Boulanger, Josiane Treuil, Bertrand Avez, Marc Bedossa, Dominique Boulmier, Marielle Le Guellec, Jean-Claude Daubert, Hervé Le Breton
BACKGROUND: High-degree atrioventricular block (HAVB) is a common complication of ST segment elevation myocardial infarction (STEMI). HAVB in STEMI is historically considered as a marker of worse outcome but overall data about HAVB in the contemporary era of mechanical reperfusion and potent antiplatelet therapies are scarce. AIM: Analysing incidence, clinical correlates and impact on inhospital outcomes of HAVB in a large prospective registry (Observatoire Régional Breton sur l'Infarctus, ORBI) of modern management of STEMI with a special focus on potential differences between patients with HAVB on admission and those who developed HAVB during hospitalisation...
January 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/26547305/jews-creativity-and-the-genius-of-disobedience
#16
Kenneth M Heilman
Jews comprise less than one percent of the world’s population; however, in the second half of the twentieth century and in the twenty-first century Jews have been awarded more than 25 % of the Nobel Prizes. Why are Jews so creative? Some have claimed, they are genetically more intelligent as determined by IQ tests. Whereas there is an intelligence threshold people must reach before being highly creative after this threshold is reached there is no strong relationship between creativity and intelligence. Creative innovation is heavily dependent upon disengagement and divergent thinking as well as subsequent convergent thinking and productivity...
February 2016: Journal of Religion and Health
https://www.readbyqxmd.com/read/26338067/description-and-phylogenetic-position-of-corlissina-maricaensis-gen-nov-sp-nov-karyorelictea-geleiidae-a-novel-interstitial-ciliate-from-brazil-with-redefinition-of-the-family-geleiidae
#17
Pedro H Campello-Nunes, Noemi Fernandes, Martin Schlegel, Inácio D Silva-Neto
Corlissina maricaensis gen. nov., sp. nov. was obtained from samples of sediment collected in a brackish lagoon of Maricá city, Rio de Janeiro state, Brazil. The morphological description was based on live observations, after protargol staining, and scanning electron microscopy. The novel species has a cylindrical body shape that is slightly contractile, 230-550 × 35-65 μm, a cytoplasm with many globular inclusions, one row of irregular cortical granules between each somatic kinety, approximately 40-62 somatic kineties, two globular macronuclei measuring 9-24 μm and one micronucleus of approximately 4-9 μm...
December 2015: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/26258507/the-complete-mitochondrial-genome-of-the-ephippus-orbis-perciformes-ephippidae
#18
Qian Wang, Zhongjie Wu, Dongyan Sun, Jian Luo
The complete mitochondrial genome of the Ephippus orbis has been sequenced. The mitochondrial genome is 16 670 bp in length, containing 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes, and one control region. The gene order and the composition of E. orbis mitochondrial genome were similar to that of most other vertebrates. The overall nucleotides base composition of the heavy strand is A (27.17%), G (16.41%), C (31.46%), and T (24.96%). With the exception of the NADH dehydrogenase subunit 6 (ND6) and eight tRNA genes, all other mitochondrial genes are encoded on the heavy strand...
September 2016: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/26238429/conservative-treatment-of-hepatic-inflammatory-pseudotumor
#19
Neus Ballester-Pla, Rafael García-Domínguez, Alexandre Pérez-Girbes, Juan Francisco Orbis-Castellanos, Eugenia Pareja
No abstract text is available yet for this article.
August 2016: Cirugía Española
https://www.readbyqxmd.com/read/26163878/a-longitudinal-study-on-determinants-of-the-intention-to-start-smoking-among-non-smoking-boys-and-girls-of-high-and-low-socioeconomic-status
#20
Henricus-Paul Cremers, Liesbeth Mercken, Hein de Vries, Anke Oenema
BACKGROUND: This study identifies differences in socio-cognitive factors as they relate to the intention to smoke among boys and girls living in high socioeconomic status (HSES) and low socioeconomic status (LSES) neighborhoods. METHODS: A total of 1,643 children (aged 10-12 years) completed a web-based questionnaire assessing their intention, attitude, social influences, and self-efficacy toward smoking at baseline and at one year follow-up. Logistic regression analyses were conducted to examine the relations between intention and predictor variables (i...
2015: BMC Public Health
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