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https://www.readbyqxmd.com/read/29141525/hyperacute-hemodynamic-effects-of-bipap-noninvasive-ventilation-in-patients-with-acute-heart-failure-and-left-ventricular-systolic-dysfunction-in-emergency-department
#1
Cinzia Moret Iurilli, Natale Daniele Brunetti, Paola Rita Di Corato, Giuseppe Salvemini, Matteo Di Biase, Marco Matteo Ciccone, Vito Procacci
BACKGROUND: Acute heart failure (AHF) is one of the leading causes of admission to emergency department (ED); severe hypoxemic AHF may be treated with noninvasive ventilation (NIV). Despite the demonstrated clinical efficacy of NIV in relieving symptoms of AHF, less is known about the hyperacute effects of bilevel positive airway pressure (BiPAP) ventilation on hemodynamics of patients admitted to ED for AHF. We therefore aimed to assess the effect of BiPAP ventilation on principal hemodynamic, respiratory, pulse oximetry, and microcirculation indexes in patients admitted to ED for AHF, needing NIV...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29138143/minimally-invasive-stand-alone-cox-maze-procedure-for-persistent-and-long-standing-persistent-atrial-fibrillation-perioperative-safety-and-5-year-outcomes
#2
Niv Ad, Sari D Holmes, Ted Friehling
BACKGROUND: Rhythm control is challenging in patients with extended atrial fibrillation (AF) duration and persistent/long-standing persistent AF. Among surgical approaches to treat AF, the Cox maze procedure performed using alternative energy sources remains superior to other beating heart techniques. We examined permanence of safety and success for the on-pump, minimally invasive, stand-alone Cox maze procedure 5 years after surgery. METHODS AND RESULTS: Stand-alone, right 5 cm minithoracotomy, Cox maze III/IV procedure for nonparoxysmal AF was conducted in 133 patients (mean follow-up=65±34 months)...
November 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29135616/intermittent-extracorporeal-co2-removal-in-chronic-obstructive-pulmonary-disease-patients-a-fiction-or-an-option
#3
Francesco Alessandri, Francesco Pugliese, Luciana Mascia, Marco V Ranieri
PURPOSE OF REVIEW: Aim of this article is to review evidence recently generated on the application of extracorporeal carbon dioxide removal (ECCO2R) in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) requiring mechanical ventilation (invasive and non invasive) for hypercapnic respiratory failure. RECENT FINDINGS: To date, the paucity of evidences on ECCO2R to decrease the rate of noninvasive ventilation (NIV) failure and to wean hypercapnic patients from invasive mechanical ventilation (IMV) precludes to systematically apply this technology to COPD patients...
November 11, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29131536/non-invasive-ventilation-use-in-status-asthmaticus-16%C3%A2-years-of-experience-in-a-tertiary-intensive-care
#4
Kirsten Rl Bond, Carl Ae Horsley, Anthony B Williams
OBJECTIVE: To describe the use of non-invasive ventilation (NIV) in adults presenting with status asthmaticus to Middlemore Hospital Critical Care Complex (CCC, South Auckland, New Zealand) from 2000 to 2015. METHOD: Retrospective review of all adult asthma admissions to the Hospital CCC between 2000 and 2015. Demographic, physiological, treatment data and blood gas results were recorded. RESULTS: There were 265 asthma admissions to Middlemore Hospital CCC during the study period...
November 12, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29130618/the-taste-of-toxicity-a-quantitative-analysis-of-bitter-and-toxic-molecules
#5
Ido Nissim, Ayana Dagan-Wiener, Masha Y Niv
The role of bitter taste-one of the few basic taste modalities-is commonly assumed to signal toxicity and alert animals against consuming harmful compounds. However, it is known that some toxic compounds are not bitter and that many bitter compounds have negligible toxicity while having important health benefits. Here we apply a quantitative analysis of the chemical space to shed light on the bitterness-toxicity relationship. Using the BitterDB dataset of bitter molecules, The BitterPredict prediction tool, and datasets of toxic compounds, we quantify the identity and similarity between bitter and toxic compounds...
November 11, 2017: IUBMB Life
https://www.readbyqxmd.com/read/29128779/noninvasive-ventilation-failure-in-pneumonia-patients-%C3%A2-65years-old-the-role-of-cough-strength
#6
Yueling Hong, Jun Duan, Linfu Bai, Xiaoli Han, Shicong Huang, Shuliang Guo
PURPOSE: To explore the association between cough strength and outcomes in elderly patients who received noninvasive ventilation (NIV) due to acute respiratory failure caused by pneumonia. MATERIALS AND METHODS: We enrolled patients ≥65years old with acute respiratory failure caused by pneumonia. Just before NIV treatment, cough strength was assessed on a cough-strength scale graded from 0 to 5. Patients graded 0-2 were defined as having no/weak coughs and those graded 3-5 were defined as having moderate/strong coughs...
November 4, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/29120907/helicobacter-pylori-infection-is-positively-associated-with-an-increased-bmi-irrespective-of-socioeconomic-status-and-other-confounders-a-cohort-study
#7
Mohamad Suki, Yaara Leibovici Weissman, Doron Boltin, David Itskoviz, Tsachi Tsadok Perets, Doron Comaneshter, Arnon Cohen, Yaron Niv, Iris Dotan, Haim Leibovitzh, Zohar Levi
BACKGROUND: Data on the association of Helicobacter pylori infection and BMI are conflicting. The fact that both H. pylori infection and BMI are associated with low socioeconomic status (SES) makes this relationship difficult to characterize. MATERIALS AND METHODS: We aimed to evaluate the association between BMI and H. pylori infection after adjusting for multiple covariates. We analyzed a cohort of 235 107 individuals aged 18 years or older, who performed a C urease breath test (C-UBT), from 2007 to 2014...
November 8, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29118858/characteristics-and-predictors-of-mortality-of-patients-with-hematologic-malignancies-requiring-invasive-mechanical-ventilation
#8
Hasan M Al-Dorzi, Haya Al Orainni, Faten Al Eid, Haytham Tlayjeh, Abedalrahman Itani, Ayman Al Hejazi, Yaseen M Arabi
RATIONALE: Acute respiratory failure (ARF) may complicate the course of hematologic malignancies (HMs). Our objective was to study the characteristics, outcomes and predictors of mortality of patients with HMs who required intubation for ARF. METHODS: This retrospective cohort study evaluated all patients with HMs who were admitted to the Intensive Care Unit (ICU) of King Abdul-Aziz Medical City-Riyadh between 2008 and 2013 and required invasive mechanical ventilation...
October 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29118336/self-assembling-dipeptide-antibacterial-nanostructures-with-membrane-disrupting-activity
#9
Lee Schnaider, Sayanti Brahmachari, Nathan W Schmidt, Bruk Mensa, Shira Shaham-Niv, Darya Bychenko, Lihi Adler-Abramovich, Linda J W Shimon, Sofiya Kolusheva, William F DeGrado, Ehud Gazit
Peptide-based supramolecular assemblies are a promising class of nanomaterials with important biomedical applications, specifically in drug delivery and tissue regeneration. However, the intrinsic antibacterial capabilities of these assemblies have been largely overlooked. The recent identification of common characteristics shared by antibacterial and self-assembling peptides provides a paradigm shift towards development of antibacterial agents. Here we present the antibacterial activity of self-assembled diphenylalanine, which emerges as the minimal model for antibacterial supramolecular polymers...
November 8, 2017: Nature Communications
https://www.readbyqxmd.com/read/29114847/intestinal-anti-transglutaminase2-iga-deposits-in-children-at-risk-for-coeliac-disease-data-from-the-prevent-cd-study
#10
Melissa Borrelli, Mariantonia Maglio, Ilma R Korponay-Szabó, Viktória Vass, M Luisa Mearin, Caroline Meijer, Hagit Niv-Drori, Carmen Ribes-Koninckx, María Roca, Raanan Shamir, Riccardo Troncone, Renata Auricchio
In Coeliac Disease (CD) anti-tissue transglutaminase2 IgA antibodies(anti-TG2) are produced and deposited in the intestine. PreventCD (www.preventcd.com) is a European multicenter study, which studies the influence of infant nutrition, and that of genetic, immunologic and other environmental factors, on the risk of developing CD. The aim of the current study was to evaluate in very early intestinal biopsies from at-risk infants the appearance of intestinal anti-TG2 deposits and their predictive value for villous atrophy...
November 8, 2017: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/29114011/albuterol-delivery-efficiency-in-a-pediatric-model-of-noninvasive-ventilation-with-double-limb-circuit
#11
Jeanne Velasco, Ariel Berlinski
BACKGROUND: Noninvasive ventilation (NIV) is used to treat respiratory failure in patients with concomitant need for aerosol delivery. Limited pediatric data are available on aerosol delivery efficiency, and none at all regarding aerosol delivery efficiency with a double-limb circuit. We compared the effect of position in the double-limb ventilator circuit, types of nebulizer, and ventilator settings on aerosol delivery efficiency in a pediatric model of NIV. We hypothesized that placing a vibrating mesh nebulizer at the ventilator and using the highest inspiratory pressures would increase aerosol delivery efficiency...
November 7, 2017: Respiratory Care
https://www.readbyqxmd.com/read/29112468/the-effects-of-on-pump-and-off-pump-coronary-artery-bypass-surgery-on-respiratory-function-in-the-early-postoperative-period
#12
Federica Chiarenza, Theodoros Tsoutsouras, Cesare Cassisi, Cristina Santonocito, Stephen Gerry, Marinella Astuto, Shane George, Filippo Sanfilippo
BACKGROUND: Respiratory complications are common after cardiac surgery and the use of extracorporeal circulation is one of the main causes of lung injury. We hypothesized a better postoperative respiratory function in off-pump coronary artery bypass grafting (OPCABG) as compared with "on-pump coronary artery bypass grafting" (ONCABG). METHODS: This is a retrospective, single-center study at a cardiothoracic intensive care unit (ICU) in a tertiary university hospital...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29111843/experience-of-using-non-invasive-ventilation-as-an-adjunct-to-airway-clearance-techniques-in-adults-with-cystic-fibrosis-a-qualitative-study
#13
Maria Cecilia Rodriguez Hortal, Anna Hedborg, Gabriele Biguet, Malin Nygren-Bonnier
BACKGROUND: Adults with cystic fibrosis (CF) suffer from abnormally thick mucus that is difficult to clear from the airways. Different airway clearance techniques (ACTs) can be used to clear secretions and non-invasive ventilation (NIV) can be used as an adjunct to these techniques. ACTs are ideally introduced at the time of diagnosis and thereafter modified throughout the patient's lifespan and disease progress. PURPOSE: The research aim was to describe adult patients' views and experiences with using NIV as an adjunct to ACT...
November 7, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29102210/postoperative-atrial-fibrillation-adding-fish-oil-to-the-fire
#14
EDITORIAL
Niv Ad, Paul S Massimiano
No abstract text is available yet for this article.
September 25, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29098459/picosecond-532-nm-neodymium-doped-yttrium-aluminium-garnet-laser-a-novel-and-promising-modality-for-the-treatment-of-caf%C3%A3-au-lait-macules
#15
Ofir Artzi, Joseph N Mehrabi, Amir Koren, Roni Niv, Moshe Lapidoth, Assi Levi
Café-au-lait macules (CALMs) present as benign hyperpigmented, well-circumscribed spots on the skin for which many patients seek treatment for aesthetic reasons. The objective of this study is to report our experience in treating CALMs using a picosecond 532-nm neodymium-doped yttrium aluminium garnet (PS 532 nm) laser. This is a retrospective case series of 16 patients with CALMs who were treated by a PS 532-nm laser (1-4 treatments, 4-8 weeks apart). Response as seen on clinical photographs was assessed by two independent dermatologists and graded on a scale of 0 (exacerbation) to 5 (95-100% improvement)...
November 2, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29096115/model-based-predictions-for-dopamine
#16
REVIEW
Angela J Langdon, Melissa J Sharpe, Geoffrey Schoenbaum, Yael Niv
Phasic dopamine responses are thought to encode a prediction-error signal consistent with model-free reinforcement learning theories. However, a number of recent findings highlight the influence of model-based computations on dopamine responses, and suggest that dopamine prediction errors reflect more dimensions of an expected outcome than scalar reward value. Here, we review a selection of these recent results and discuss the implications and complications of model-based predictions for computational theories of dopamine and learning...
October 30, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/29092793/proteomic-composition-of-nipah-virus-like-particles
#17
Natalia Mara Vera-Velasco, Maria Jesús García-Murria, Manuel M Sánchez Del Pino, Ismael Mingarro, Luis Martinez-Gil
Virions are often described as virus-only entities with no cellular components with the exception of the lipids in their membranes. However, advances in proteomics are revealing substantial amounts of host proteins in the viral particles. In the case of Nipah virus (NiV), the viral components in the virion have been known for some time. Nonetheless, no information has been obtained regarding the cellular proteins in the viral particles. To address this question, we produced Virus-Like Particles (VLPs) for NiV by expressing the F, G and M proteins in human-derived cells...
October 29, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/29083022/predictors-of-noninvasive-ventilation-failure-in-critically-ill-obese-patients-a-brief-narrative-review
#18
Antonello Nicolini, Malcom Lemyze, Antonio Esquinas, Cornelius Barlascini, Maurizio A Cavalleri
 Non-invasive ventilation ( NIV ) has been used successfully for the management of acute respiratory failure (ARF) more often in the last two decades than previously. Unfortunately, NIV can have failure rates ranging from 5% to 50% and patient selection is the key to success. There are particular groups of patients that are more likely to benefit from NIV. For patients with hypoventilation syndrome (OHS) this treatment can be beneficial. This review seeks to evaluate the effectiveness of NIV in acute ARF and determine predictors of NIV failure in morbidly obese patients...
October 30, 2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/29068881/correction-of-paradoxical-ribcage-motion-in-scoliosis-by-non-invasive-ventilation
#19
William J M Kinnear, Milind Sovani, Arun Khanna, Juliet Colt
STUDY DESIGN: Observational study of ribcage motion in scoliosis. OBJECTIVE: To see if non-invasive ventilation corrected paradoxical inward motion of the ribs during inspiration. SUMMARY OF BACKGROUND DATA: Paradoxical inward motion of the ribs is observed following rib fractures, low cervical cord injury and in chronic obstructive pulmonary disease. It is not well recognised in scoliosis and the mechanism in this group has not been studied...
October 24, 2017: Spine
https://www.readbyqxmd.com/read/29068686/multimycotoxin-lc-ms-ms-analysis-in-tea-beverages-after-dispersive-liquid-liquid-microextraction-dllme
#20
Noelia Pallarés, Guillermina Font, Jordi Manes, Emilia Ferrer
The aim of the present study was to develop a multimycotoxin Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) method with a dispersive liquid-liquid microextraction procedure (DLLME) for the analysis of AFs, 3aDON, 15aDON, NIV, HT-2, T-2, ZEA, OTA, ENNs and BEA in tea beverages and to evaluate their mycotoxin contents. The proposed method was characterized in terms of linearity, limits of detection (LODs), limits of quantification (LOQs), recoveries, repeatability (intra-day precision), reproducibility (inter-day precision), and matrix effects to check suitability...
October 25, 2017: Journal of Agricultural and Food Chemistry
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