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https://www.readbyqxmd.com/read/28895917/uwb-monitoring-system-for-aal-applications
#1
Jerzy Kolakowski, Vitomir Djaja-Josko, Marcin Kolakowski
Independent living of elderly persons in their homes requires support that can be provided with modern assistive technologies. Monitoring of elderly persons behaviour delivers valuable information that can be used for diagnosis and detection of health problems as well as triggering alerts in emergency situations. The paper includes a description of the ultra wideband system developed within Networked InfrasTructure for Innovative home Care Solutions (NITICS) Active and Assisted Living (AAL) project. The system can be used as a component of AAL platforms...
September 12, 2017: Sensors
https://www.readbyqxmd.com/read/28853968/evaluation-of-autologous-platelet-rich-plasma-plus-ablative-carbon-dioxide-fractional-laser-in-the-treatment-of-acne-scars
#2
Ahmed Mohammed Abdel Aal, Ibrahim Maeraj Ibrahim, Nevein Ahmed Sami, Ibrahim Mohammed Abdel Kareem
INTRODUCTION: Acne scar is a common distressing complication of acne vulgaris. CO2 laser resurfacing proved effective for treatment of such problem but the associated complications may limit its use. Platelet rich plasma (PRP) may increase the chance of favorable outcome. AIM OF THE WORK: To evaluate the synergistic effects of autologous PRP with fractional CO2 laser resurfacing in treatment of acne scars among Egyptian patients. PATIENTS AND METHOD: This study included 30 patients suffering from post-acne scars...
August 30, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28829323/channel-deviation-based-power-control-in-body-area-networks
#3
Son Dinh Van, Simon L Cotton, David B Smith
Internet enabled body area networks (BANs) will form a core part of future remote health monitoring and Ambient Assisted Living (AAL) technology. In BAN applications, due to the dynamic nature of human activity, the off-body BAN channel can be prone to deep fading caused by body shadowing and multipath fading. Using this knowledge, we present some novel practical adaptive power control protocols based on the channel deviation to simultaneously prolong the lifetime of wearable devices and reduce outage probability...
August 18, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28800497/glycoconjugate-probes-containing-a-core-fucosylated-n-glycan-trisaccharide-for-fucose-lectin-identification-and-purification
#4
Deqin Cai, Chaochao Xun, Feng Tang, Xiaobo Tian, Liyun Yang, Kan Ding, Wenzhe Li, Zhiping Le, Wei Huang
Glyco-PAMAM dendrimers and glyco-agarose beads bearing a core-fucosylated N-glycan trisaccharide GlcNAcβ1,4(Fucα1,6)GlcNAc or a non-fucose disaccharide GlcNAcβ1,4GlcNAc were successfully synthesized and characterized by monosaccharide analysis with HPAEC-PAD technique. These glycoconjugates as fucose lectin probes were applied in fucose-specific lectin detection and purification. The model fucose lectin AAL indicated binding activity with the FITC-labeled PAMAM carrying core-fucose trisaccharide. An affinity chromatography column stuffed with the agarose beads carrying core-fucosylated trisaccharide exhibited a good specificity in purification of AAL than non-fucose disaccharide agarose beads...
September 8, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28796600/interoperable-end-to-end-remote-patient-monitoring-platform-based-on-ieee-11073-phd-and-zigbee-health-care-profile
#5
Malcolm Clarke, Joost de Folter, Vivek Verma, Hulya Gokalp
This paper describes the implementation of an end-to-end remote monitoring platform based on the IEEE 11073 standards for Personal Health Devices (PHD). It provides an overview of the concepts and approaches and describes how the standard has been optimized for small devices with limited resources of processor, memory and power and that use short range wireless technology. It explains aspects of IEEE 11073, including the Domain Information Model, state model and nomenclature, and how these support its plug-and-play architecture...
August 7, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28777753/gender-based-cerebral-perfusion-differences-in-46-034-functional-neuroimaging-scans
#6
Daniel G Amen, Manuel Trujillo, David Keator, Derek V Taylor, Kristen Willeumier, Somayeh Meysami, Cyrus A Raji
BACKGROUND: Studies have reported that females have widespread increases in regional cerebral blood flow, but the studies were relatively small and inconsistent. OBJECTIVE: Here we analyzed a healthy and very large psychiatric population to determine the effect of gender, using single photon emission computed tomography (SPECT). METHODS: Whole brain and region of interest (ROI) gender differences were analyzed in a total of 46,034 SPECT scans at baseline and concentration...
August 4, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28777091/the-quorum-quenching-lactonase-from-alicyclobacter-acidoterrestris-purification-kinetic-characterization-crystallization-and-crystallographic-analysis
#7
Celine Bergonzi, Michael Schwab, Eric Chabriere, Mikael Elias
Lactonases comprise a class of enzymes that hydrolyze lactones, including acyl-homoserine lactones (AHLs); the latter are used as chemical signaling molecules by numerous Gram-negative bacteria. Lactonases have therefore been demonstrated to quench AHL-based bacterial communication. In particular, lactonases are capable of inhibiting bacterial behaviors that depend on these chemicals, such as the formation of biofilms or the expression of virulence factors. A novel representative from the metallo-β-lactamase superfamily, named AaL, was isolated from the thermoacidophilic bacterium Alicyclobacter acidoterrestris...
August 1, 2017: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/28755328/alternaria-toxins-in-south-african-sunflower-seeds-cooperative-study
#8
Sebastian Hickert, Lena Hermes, Lucas Maciel Mauriz Marques, Christine Focke, Benedikt Cramer, Norberto Peporine Lopes, Bradley Flett, Hans-Ulrich Humpf
Sunflower seed samples (N = 80) from different sunflower cultivars originating from different localities in South Africa were analyzed for 15 toxins produced by fungi of the genus Alternaria by means of a simple one-step extraction dilute-and-shoot HPLC-MS/MS approach. References for valine-tenuazonic acid (Val-TeA), altenusin (ALTS), and altenuisol (ALTSOH) were isolated from fungal culture extracts and spectroscopically characterized. Additionally, valine-tenuazonic acid was tested regarding its cytotoxicity in comparison with tenuazonic acid (TeA) and showed less activity on HT-29 cells...
July 28, 2017: Mycotoxin Research
https://www.readbyqxmd.com/read/28750938/impact-of-cryopreservation-method-on-dromedary-camel-ovary-structure-viability-and-development-of-antral-follicular-oocytes
#9
M M Madboly, E S Abdel-Aal, Eitedal H Elsayed
The objectives of this study were, a) to compare two different vitrification techniques, the solid surface vitrification (SSV) and direct vitrification (DV) method, b) to evaluate the effect of four cryoprotectant agents and their toxicity on the morphological appearance and ultrastructural of camel ovarian cortex, c) to examine the development of oocytes recovered from the vitrified ovarian cortex. Fragments of ovarian cortex were exposed to equilibration solution consisting of TCM- 199 with 10% fetal camel serum (FCS); 0...
July 19, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28749356/improving-alzheimeres-disease-classification-by-combining-multiple-measures
#10
Jin Liu, Jianxin Wang, Zhenjun Tang, Bin Hu, Fang-Xiang Wu, Yi Pan
Several anatomical magnetic resonance imaging (MRI) markers for Alzheimer's disease (AD) have been identified. Cortical gray matter volume, cortical thickness, and subcortical volume have been used successfully to assist the diagnosis of Alzheimer's disease (AD) including its early warning and developing stages, e.g., mild cognitive impairment (MCI) including MCI converted to AD (MCIc) and MCI not converted to AD (MCInc). Currently, these anatomical MRI measures have mainly been used separately. Thus, the full potential of anatomical MRI scans for AD diagnosis might not yet have been used optimally...
July 25, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28748044/visualizing-the-dental-biofilm-matrix-by-means-of-fluorescence-lectin-binding-analysis
#11
Pune N Tawakoli, Thomas R Neu, Mette M Busck, Ute Kuhlicke, Andreas Schramm, Thomas Attin, Daniel B Wiedemeier, Sebastian Schlafer
The extracellular matrix is a poorly studied, yet important component of dental biofilms. Fluorescence lectin-binding analysis (FLBA) is a powerful tool to characterize glycoconjugates in the biofilm matrix. This study aimed to systematically investigate the ability of 75 fluorescently labeled lectins to visualize and quantify extracellular glycoconjugates in dental biofilms. Lectin binding was screened on pooled supragingival biofilm samples collected from 76 subjects using confocal microscopy. FLBA was then performed with 10 selected lectins on biofilms grown in situ for 48 h in the absence of sucrose...
2017: Journal of Oral Microbiology
https://www.readbyqxmd.com/read/28702344/directional-information-flow-in-patients-with-alzheimer-s-disease-a-source-space-resting-state-meg-study
#12
M M A Engels, M Yu, C J Stam, A A Gouw, W M van der Flier, Ph Scheltens, E C W van Straaten, A Hillebrand
In a recent magnetoencephalography (MEG) study, we found posterior-to-anterior information flow over the cortex in higher frequency bands in healthy subjects, with a reversed pattern in the theta band. A disruption of information flow may underlie clinical symptoms in Alzheimer's disease (AD). In AD, highly connected regions (hubs) in posterior areas are mostly disrupted. We therefore hypothesized that in AD the information flow from these hub regions would be disturbed. We used resting-state MEG recordings from 27 early-onset AD patients and 26 healthy controls...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28679901/substitution-of-assisted-living-services-by-assistive-technology-experts-opinions-and-technical-feasibility
#13
Jonas Schwartze, Arianit Prekazi, Harald Schrom, Michael Marschollek
Ambient assisted living (AAL) may support ageing in place but is primarily driven by technology. The aim of this work is, to identifying reasons to move into assisted living institutions, their range of service and possible substitutability. We did semi-structured interviews with five experts from assisted living institutions and used results to design and implement assistive technologies in an AAL environment using BASIS, a cross domain bus system for smart buildings. Reasons for moving to assisted living institutions are expected benefits for chronic health problems, safety, social isolation and carefree living...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28657344/value-of-frequency-domain-resting-state-functional-magnetic-resonance-imaging-metrics-amplitude-of-low-frequency-fluctuation-and-functional-amplitude-of-low-frequency-fluctuation-in-the-assessment-of-brain-tumor-induced-neurovascular-uncoupling
#14
Shruti Agarwal, Hanzhang Lu, Jay J Pillai
The aim of this study was to explore whether the phenomenon of brain tumor-related neurovascular uncoupling (NVU) in resting-state blood oxygen level-dependent functional magnetic resonance imaging (BOLD fMRI) (rsfMRI) may also affect the resting-state fMRI (rsfMRI) frequency domain metrics the amplitude of low-frequency fluctuation (ALFF) and fractional ALFF (fALFF). Twelve de novo brain tumor patients, who underwent clinical fMRI examinations, including task-based fMRI (tbfMRI) and rsfMRI, were included in this Institutional Review Board-approved study...
August 2017: Brain Connectivity
https://www.readbyqxmd.com/read/28627880/site-specific-fucosylation-analysis-identifying-glycoproteins-associated-with-aggressive-prostate-cancer-cell-lines-using-tandem-affinity-enrichments-of-intact-glycopeptides-followed-by-mass-spectrometry
#15
Jianliang Zhou, Weiming Yang, Yingwei Hu, Naseruddin Höti, Yang Liu, Punit Shah, Shisheng Sun, David Clark, Stefani Thomas, Hui Zhang
Fucosylation (Fuc) of glycoproteins plays an important role in regulating protein function and has been associated with the development of several cancer types including prostate cancer (Pca). Therefore, the research of Fuc glycoproteins has attracted increasing attention recently in the analytical field. Herein, a strategy based on lectin affinity enrichments of intact glycopeptides followed by mass spectrometry has been established to evaluate the specificities of various Fuc-binding lectins for glycosite-specific Fuc analysis of nonaggressive (NAG) and aggressive (AG) Pca cell lines...
July 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28625592/a-critical-analysis-of-stented-and-unstented-tubularized-incised-plate-urethroplasty-through-a-prospective-randomized-study-and-assessment-of-factors-influencing-the-functional-and-cosmetic-outcomes
#16
Tarek M El-Karamany, Ahmed M Al-Adl, Rabea G Omar, Ashraf M Abdel Aal, Amr S Eldakhakhny, Shabieb A Abdelbaki
OBJECTIVE: To compare, functionally and aesthetically, stented and unstented tubularized incised plate urethroplasty (TIPU). In addition, predictors of repair success were investigated. MATERIALS AND METHODS: One hundred ten children with distal hypospadias were included in this study. The length and width of the urethral plate (UP) and transverse glans diameter (TGD) were measured. Patients were randomized into two groups: stented and unstented TIPU. Postoperative assessment of pain was done using Face, Legs, Activity, Cry, Consolability (FLACC) scale, and cosmetic outcome was evaluated using hypospadias objective scoring evaluation...
June 15, 2017: Urology
https://www.readbyqxmd.com/read/28600738/functional-brain-networks-reconstruction-using-group-sparsity-regularized-learning
#17
Qinghua Zhao, Will X Y Li, Xi Jiang, Jinglei Lv, Jianfeng Lu, Tianming Liu
Investigating functional brain networks and patterns using sparse representation of fMRI data has received significant interests in the neuroimaging community. It has been reported that sparse representation is effective in reconstructing concurrent and interactive functional brain networks. To date, most of data-driven network reconstruction approaches rarely take consideration of anatomical structures, which are the substrate of brain function. Furthermore, it has been rarely explored whether structured sparse representation with anatomical guidance could facilitate functional networks reconstruction...
June 9, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28584332/immunological-and-genotoxic-effects-of-occupational-exposure-to-%C3%AE-cypermethrin-pesticide
#18
El-Sayed El-Okda, Mona Abdel-Aal Abdel-Hamid, Ahmed Mohamed Hamdy
OBJECTIVES: The aim of this work has been to find out the occupational oxidative stress, immunological and genotoxic health hazards among α-cypermethrin (CYP) pesticide-exposed workers. MATERIAL AND METHODS: A cross-sectional study was performed including 200 workers divided into 3 groups according to the level of exposure: highly exposed group (50 workers), moderately exposed group (50 workers) and unexposed group (100 workers). All workers were subjected to detailed laboratory investigation for gene P53 mutations, immunological parameters as a cluster of differentiation into 3 percentage (CD3%), CD4% and CD8% in addition to peripheral blood total leukocytic and platelet counts that were measured...
June 5, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28543283/targeting-pp2a-and-proteasome-activity-ameliorates-features-of-allergic-airway-disease-in-mice
#19
P M Nair, M R Starkey, T J Haw, G Liu, J C Horvat, J C Morris, N M Verrills, A R Clark, A J Ammit, P M Hansbro
BACKGROUND: Asthma is an allergic airway disease (AAD) caused by aberrant immune responses to allergens. Protein phosphatase-2A (PP2A) is an abundant serine/threonine phosphatase with anti-inflammatory activity. The ubiquitin proteasome system (UPS) controls many cellular processes, including the initiation of inflammatory responses by protein degradation. We assessed whether enhancing PP2A activity with fingolimod (FTY720) or 2-amino-4-(4-(heptyloxy) phenyl)-2-methylbutan-1-ol (AAL(S) ), or inhibiting proteasome activity with bortezomib (BORT), could suppress experimental AAD...
May 24, 2017: Allergy
https://www.readbyqxmd.com/read/28520865/impact-of-an-integrated-antibiotic-allergy-testing-program-on-antimicrobial-stewardship-a-multicenter-evaluation
#20
Jason A Trubiano, Karin A Thursky, Andrew J Stewardson, Karen Urbancic, Leon J Worth, Cheryl Jackson, Wendy Stevenson, Michael Sutherland, Monica A Slavin, M Lindsay Grayson, Elizabeth J Phillips
Background.: Despite the high prevalence of patient-reported antibiotic allergy (so-called antibiotic allergy labels [AALs]) and their impact on antibiotic prescribing, incorporation of antibiotic allergy testing (AAT) into antimicrobial stewardship (AMS) programs (AAT-AMS) is not widespread. We aimed to evaluate the impact of an AAT-AMS program on AAL prevalence, antibiotic usage, and appropriateness of prescribing. Methods.: AAT-AMS was implemented at two large Australian hospitals during a 14-month period beginning May 2015...
May 18, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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