keyword
MENU ▼
Read by QxMD icon Read
search

AAL

keyword
https://www.readbyqxmd.com/read/29315346/a-detection-and-quantification-label-free-tool-to-speed-up-downstream-processing-of-model-mucins
#1
Sofia B Carvalho, Ana Sofia Moreira, Joana Gomes, Manuel J T Carrondo, David J Thornton, Paula M Alves, Julia Costa, Cristina Peixoto
Mucins are high-molecular weight glycoproteins (0.25-20 MDa) containing one or more domains that are heavily O-glycosylated. Their implications as targets for cancer treatment have increased the interest in these glycoproteins, mainly in the fields of vaccines and antibodies. However, mucins present high heterogeneity, posing challenges that affect purification processes and quality control analysis. In that sense, it is necessary to develop and improve downstream processes and analytical methods to characterize these products...
2018: PloS One
https://www.readbyqxmd.com/read/29315232/recognition-of-activities-of-daily-living-based-on-environmental-analyses-using-audio-fingerprinting-techniques-a-systematic-review
#2
REVIEW
Ivan Miguel Pires, Rui Santos, Nuno Pombo, Nuno M Garcia, Francisco Flórez-Revuelta, Susanna Spinsante, Rossitza Goleva, Eftim Zdravevski
An increase in the accuracy of identification of Activities of Daily Living (ADL) is very important for different goals of Enhanced Living Environments and for Ambient Assisted Living (AAL) tasks. This increase may be achieved through identification of the surrounding environment. Although this is usually used to identify the location, ADL recognition can be improved with the identification of the sound in that particular environment. This paper reviews audio fingerprinting techniques that can be used with the acoustic data acquired from mobile devices...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29299683/hpv-genotypes-detected-by-linear-array-and-next-generation-sequencing-in-anal-samples-from-hiv-positive-men-who-have-sex-with-men-in-mexico
#3
Luz A González-Hernández, María G Flores-Miramontes, Adriana Aguilar-Lemarroy, Krissya S Quintanilla-Peña, Fabiola L Martin-Amaya-Barajas, Moisés Ramos-Solano, Luis F Enciso Gómez, Jaime F Andrade-Villanueva, Luis F Jave-Suárez
The incidence of anal cancer has been rising, especially in HIV+ patients and has been associated with HPV infection. HIV+ patients are more at risk of HPV coinfection and are seven times more likely to have persistent HPV infection; moreover, HIV+ men have an increased risk of developing anal cancer compared to HIV+ women. The development of screening strategies for the detection of HPV in HIV+ men is of major importance; however, there is not enough information about the HPV genotypes and variants that are colonizing the anal epithelia of HIV+ men in diverse geographical regions...
January 3, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29284675/test-retest-reproducibility-for-the-tau-pet-imaging-agent-flortaucipir-f-18
#4
Michael D Devous, Abhinay D Joshi, Michael Navitsky, Sudeepti Southekal, Michael J Pontecorvo, Haiqing Shen, Ming Lu, William R Shankle, John P Seibyl, Ken Marek, Mark A Mintun
Background: Alzheimer's disease (AD) is characterized by beta-amyloid plaques (Aβ) and tau neurofibrillary tangles (NFTs). There are several PET imaging biomarkers for Aβ including 11C-PiB and 18F florbetapir. Recently, PET tracers for tau NFTs have become available and have shown utility in detection and monitoring of neurofibrillary pathology over time. Flortaucipir F 18 is one such tracer. Initial clinical studies indicated greater tau binding in AD and MCI patients compared to controls in a pattern consistent with tau pathology observed at autopsy...
December 28, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29274330/a-new-enzyme-immunoassay-for-the-determination-of-highly-sialylated-and-fucosylated-human-%C3%AE-1-acid-glycoprotein-as-a-biomarker-of-tumorigenesis
#5
Shin Yazawa, Takehiko Yokobori, Kyoichi Kaira, Hiroyuki Kuwano, Takayuki Asao
BACKGROUND: Upon initiation and progression of cancer, α1-acid glycoprotein (AGP) possessing highly sialylated and fucosylated glycans appears in the serum, and recently has attracted a great deal of attention, as a potential biomarker of tumorigenesis in humans. To establish a rapid and precise method for the quantitative assay of fucosylated AGP in serum samples, we developed an enzyme immunoassay (EIA) bearing an anti-AGP antibody and a fucose-binding lectin, Aleuria aurantia (AAL) with additional endeavor to improved sample handling, and antibody preparations...
December 20, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29240523/injectable-platelet-rich-fibrin-using-the-low-speed-centrifugation-concept-improves-cartilage-regeneration-when-compared-to-platelet-rich-plasma
#6
Mustafa Abd El Raouf, Xuzhu Wang, Si Miusi, Jihua Chai, Abdel Basit Mohamed AbdEl-Aal, Mekkawy M Nefissa Helmy, Shahram Ghanaati, Joseph Choukroun, Elisa Choukroun, Yufeng Zhang, Richard J Miron
The aim of the present study was to evaluate the effect of injectable platelet-rich fibrin (i-PRF) on cultivated chondrocytes and osteochondral regeneration in critical-sized osteochondral defect of the rabbit's knee in comparison to autologous platelet-rich plasma (PRP). Chondrocytes were first investigated for their ability to proliferate and differentiate in response to PRP and i-PRF. Thereafter, full-thickness critical-sized osteochondral defects 5 mm in diameter and 5 mm in depth were created in the knee joint of 12 adult female New Zealand White rabbits...
December 14, 2017: Platelets
https://www.readbyqxmd.com/read/29234599/selecting-the-most-relevant-brain-regions-to-discriminate-alzheimer-s-disease-patients-from-healthy-controls-using-multiple-kernel-learning-a-comparison-across-functional-and-structural-imaging-modalities-and-atlases
#7
Jane Maryam Rondina, Luiz Kobuti Ferreira, Fabio Luis de Souza Duran, Rodrigo Kubo, Carla Rachel Ono, Claudia Costa Leite, Jerusa Smid, Ricardo Nitrini, Carlos Alberto Buchpiguel, Geraldo F Busatto
Background: Machine learning techniques such as support vector machine (SVM) have been applied recently in order to accurately classify individuals with neuropsychiatric disorders such as Alzheimer's disease (AD) based on neuroimaging data. However, the multivariate nature of the SVM approach often precludes the identification of the brain regions that contribute most to classification accuracy. Multiple kernel learning (MKL) is a sparse machine learning method that allows the identification of the most relevant sources for the classification...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29232414/influence-of-trp-flipping-on-carbohydrate-binding-in-lectins-an-example-on-aleuria-aurantia-lectin-aal
#8
Josef Houser, Stanislav Kozmon, Deepti Mishra, Sushil K Mishra, Patrick R Romano, Michaela Wimmerová, Jaroslav Koča
Protein-carbohydrate interactions are very often mediated by the stacking CH-π interactions involving the side chains of aromatic amino acids such as tryptophan (Trp), tyrosine (Tyr) or phenylalanine (Phe). Especially suitable for stacking is the Trp residue. Analysis of the PDB database shows Trp stacking for 265 carbohydrate or carbohydrate like ligands in 5 208 Trp containing motives. An appropriate model system to study such an interaction is the AAL lectin family where the stacking interactions play a crucial role and are thought to be a driving force for carbohydrate binding...
2017: PloS One
https://www.readbyqxmd.com/read/29210428/lectin-gated-and-glycan-functionalized-mesoporous-silica-nanocontainers-for-targeting-cancer-cells-overexpressing-lewis-x-antigen
#9
R Bhat, I García, E Aznar, B Arnaiz, M C Martínez-Bisbal, L M Liz-Marzán, S Penadés, R Martínez-Máñez
Gated mesoporous silica nanoparticles can deliver payload upon the application of a predefined stimulus, and therefore are promising drug delivery systems. Despite their important role, relatively low emphasis has been placed on the design of gating systems that actively target carbohydrate tumor cell membrane receptors. We describe herein a new Lewis X (Lex) antigen-targeted delivery system comprising mesoporous silica nanoparticles (MSNs) loaded with ATTO 430LS dye, functionalized with a Lex derivative (1) and capped with a fucose-specific carbohydrate-binding protein (Aleuria aurantia lectin (AAL))...
December 6, 2017: Nanoscale
https://www.readbyqxmd.com/read/29196694/latent-tuberculosis-infection-among-patients-with-erectile-dysfunction
#10
Ahmad F A Hasanain, Ali M A Mahran, Ahmed S Safwat, Amany M A Nafee, Ali A H Zayed, Sherif M Abdel-Aal, Sally M Bakkar, Ahmad Elbadry I Abonnoor
No previous studies have investigated the prevalence of latent tuberculosis infection (LTBI) among patients with erectile dysfunction (ED) or its contribution to the development of high-grade ED through a process of chronic inflammation-induced atherosclerosis. The aim of this study was to determine the frequency of LTBI among patients with erectile dysfunction and to explore the contribution of LTBI to high-grade ED. For all the study sample, clinical evaluation, imaging studies, and laboratory investigations were provided...
December 1, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/29195932/effect-of-processing-on-phenolic-acids-composition-and-radical-scavenging-capacity-of-barley-pasta
#11
Rosanna De Paula, Iwona Rabalski, Maria Cristina Messia, El-Sayed M Abdel-Aal, Emanuele Marconi
Phenolic acids, total phenolics content and DPPH radical scavenging capacity in raw ingredients, fresh and dried spaghetti, and in uncooked and cooked spaghetti were evaluated and compared with semolina spaghetti as a reference. Ferulic acid was the major phenolic acid found in the free and bound phenolic extracts in all the investigated pasta samples. The addition of barley flour into pasta at incorporation levels of 30, 50 and 100% increased phenolic acids and total phenolics content. Pasta processing did not significantly affect the total phenolics content and free radical scavenging capacity, but a significant reduction in total phenolic acids measured by HPLC was found...
December 2017: Food Research International
https://www.readbyqxmd.com/read/29184260/topical-effects-of-artemisia-absinthium-ointment-and-liniment-in-comparison-with-piroxicam-gel-in-patients-with-knee-joint-osteoarthritis-a-randomized-double-blind-controlled-trial
#12
Zahra Basiri, Fatemeh Zeraati, Farzaneh Esna-Ashari, Farshid Mohammadi, Keyvan Razzaghi, Malihe Araghchian, Shirin Moradkhani
Background: Pain alleviation and improvement of functional status are the main objectives in the treatment of osteoarthritis. Artemisia absinthium (AA) was used traditionally in reducing pain and inflammation. The aim of the present study was to compare the effects of topical formulations of AA and piroxicam gel (PG) among patients with knee osteoarthritis. Methods: In total, 90 outpatients aged 30-70 years with the diagnosis of primary osteoarthritis in at least one knee were enrolled in a randomized double-blind clinical trial...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29167592/using-large-scale-granger-causality-to-study-changes-in-brain-network-properties-in-the-clinically-isolated-syndrome-cis-stage-of-multiple-sclerosis
#13
Anas Z Abidin, Udaysankar Chockanathan, Adora M DSouza, Matilde Inglese, Axel Wismüller
Clinically Isolated Syndrome (CIS) is often considered to be the first neurological episode associated with Multiple sclerosis (MS). At an early stage the inflammatory demyelination occurring in the CNS can manifest as a change in neuronal metabolism, with multiple asymptomatic white matter lesions detected in clinical MRI. Such damage may induce topological changes of brain networks, which can be captured by advanced functional MRI (fMRI) analysis techniques. We test this hypothesis by capturing the effective relationships of 90 brain regions, defined in the Automated Anatomic Labeling (AAL) atlas, using a large-scale Granger Causality (lsGC) framework...
March 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/29163844/identifying-current-and-remitted-major-depressive-disorder-with-the-hurst-exponent-a-comparative-study-on-two-automated-anatomical-labeling-atlases
#14
Bin Jing, Zhuqing Long, Han Liu, Huagang Yan, Jianxin Dong, Xiao Mo, Dan Li, Chunhong Liu, Haiyun Li
Major depressive disorder (MDD) is a leading world-wide psychiatric disorder with high recurrence rate, therefore, it is desirable to identify current MDD (cMDD) and remitted MDD (rMDD) for their appropriate therapeutic interventions. In the study, 19 cMDD, 19 rMDD and 19 well-matched healthy controls (HC) were enrolled and scanned with the resting-state functional magnetic resonance imaging (rs-fMRI). The Hurst exponent (HE) of rs-fMRI in AAL-90 and AAL-1024 atlases were calculated and compared between groups...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29157726/adaptive-and-technology-independent-architecture-for-fault-tolerant-distributed-aal-solutions
#15
Michael Schmidt, Roman Obermaisser
Today's architectures for Ambient Assisted Living (AAL) must cope with a variety of challenges like flawless sensor integration and time synchronization (e.g. for sensor data fusion) while abstracting from the underlying technologies at the same time. Furthermore, an architecture for AAL must be capable to manage distributed application scenarios in order to support elderly people in all situations of their everyday life. This encompasses not just life at home but in particular the mobility of elderly people (e...
November 6, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29153863/assessment-of-uranium-release-to-the-environment-from-a-disabled-uranium-mine-in-brazil
#16
Wagner de Souza Pereira, Alphonse Germaine Albert Charles Kelecom, Ademir Xavier da Silva, Alessander Sá do Carmo, Delcy de Azavedo Py Júnior
The Ore Treatment Unit (in Portuguese Unidade de Tratamento de Minérios - UTM) located in Caldas, MG, Brazil is a disabled uranium mine. Environmental conditions generate acid drainage leaching metals and radionuclides from the waste rock pile. This drainage is treated to remove the heavy metals and radionuclides, before allowing the release of the effluent to the environment. To validate the treatment, samples of the released effluents were collected at the interface of the installation with the environment...
November 16, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29147635/global-and-targeted-pathway-impact-of-gliomas-on-white-matter-integrity-based-on-lobar-localization
#17
David R Ormond, Shawn D'Souza, John A Thompson
Primary brain tumors comprise 28% of all tumors and 80% of malignant tumors. Pathophysiology of high-grade gliomas includes significant distortion of white matter architecture, necrosis, the breakdown of the blood brain barrier, and increased intracranial pressure. Diffusion tensor imaging (DTI), a diffusion weighted imaging technique, can be used to assess white matter architecture. Use of DTI as a non-invasive pathophysiological tool to analyze glioma impact on white matter microstructure has yet to be fully explored...
September 7, 2017: Curēus
https://www.readbyqxmd.com/read/29137174/hdomo-smart-sensor-integration-for-an-active-and-independent-longevity-of-the-elderly
#18
Emanuele Frontoni, Rama Pollini, Paola Russo, Primo Zingaretti, Graziano Cerri
The aim of this paper is to present the main results of HDOMO, an Ambient Assisted Living (AAL) project that involved 16 Small and Medium Enterprises (SMEs) and 2 research institutes. The objective of the project was to create an autonomous and automated domestic environment, primarily for elderly people and people with physical and motor disabilities. A known and familiar environment should help users in their daily activities and it should act as a virtual caregiver by calling, if necessary, relief efforts...
November 13, 2017: Sensors
https://www.readbyqxmd.com/read/29130773/alteration-of-salivary-glycopatterns-in-oral-lichen-planus
#19
Liang Fang, Qing Liu, Pengfei He, Xinwen Wang, Ying Wang, Minghui Wei, Lihua Chen
BACKGROUND: Oral lichen planus (OLP) is one of the most common oral mucosal lesions affecting 0.5% to 2% of the adult population. It is difficult to distinguish between OLP and other oral mucosal diseases. Structural changes in the glycans of saliva proteins might be reliable indicators of OLP. However, little is known about the alteration of salivary glycopatterns during OLP. OBJECTIVE: We aimed to investigate the alterations of salivary protein glycosylation related to OLP...
November 13, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29118535/rapid-versus-gradual-bladder-decompression-in-acute-urinary-retention
#20
Mohamed H Etafy, Fatma H Saleh, Cervando Ortiz-Vanderdys, Alaa Hamada, Alaa M Refaat, Mohamed Abdel Aal, Hazem Deif, Maher Gawish, Ashraf H Abdellatif, Khaled Gadalla
Objective: To demonstrate a benefit in diminished adverse events such as hypotension and hematuria with gradual drainage of the bladder when compared to rapid decompression in patients with acute urinary retention (AUR) due to benign prostatic hyperplasia in a case-control study. Methods: Sixty-two patients matched our selection criteria presenting with AUR. They were divided into two groups - the first was managed by rapid drainage of the bladder, the second was managed by gradual drainage through a urethral catheter (The first 100 mL immediately evacuated, then the rest evacuated gradually over 2 h)...
October 2017: Urology Annals
keyword
keyword
29239
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"