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https://www.readbyqxmd.com/read/29334005/physiological-correlations-with-short-medium-and-long-cycling-time-trial-performance
#1
Fernando K Borszcz, Artur F Tramontin, Kristopher M de Souza, Lorival J Carminatti, Vitor P Costa
PURPOSE: Several studies have demonstrated that physiological variables predict cycling endurance performance. However, it is still unclear whether the predictors will change over different performance durations. The aim of this study was to assess the correlations between physiological variables and cycling time trials with different durations. METHODS: Twenty trained male cyclists (maximal oxygen uptake [VO2max] = 60.5 ± 5.6 mL/kg/min) performed 4 separate experimental trials during a 2-week period...
January 15, 2018: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29332749/long-term-effect-of-direction-movement-control-training-on-female-patients-with-chronic-neck-pain
#2
Zohreh Khosrokiani, Amir Letafatkar, Yahya Sokhanguei
BACKGROUND: Treatment of movement faults in the neck is known as an important factor in treatment of chronic neck pain. Along with the identification of site and direction of the faults, direction-movement control intervention retrains the control of the movement faults. PURPOSE: This study was designed to investigate long-term effects of a direction-movement control training on pain, disability, head repositioning accuracy, function, cervical flexor endurance, and range of motion in female patients with chronic nonspecific neck pain...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29331050/exercise-counteracts-lipotoxicity-by-improving-lipid-turnover-and-lipid-droplet-quality
#3
Evelyn Zacharewicz, Matthijs K C Hesselink, Patrick Schrauwen
The incidence of obesity and metabolic disease, such as type 2 diabetes mellitus (T2D), are rising globally. Dietary lipid over-supply leads to lipid accumulation at ectopic sites, such as skeletal muscle. Ectopic lipid storage is highly correlated with insulin resistance and T2D, likely due to a loss of metabolic flexibility - the capacity to switch between fat and glucose oxidation upon insulin stimulation - and cellular dysfunction because of lipotoxicity. However, muscle lipid levels are also elevated in endurance trained athletes, presenting a paradoxical phenotype of increased intramuscular lipids along with high insulin sensitivity - the "athletes' paradox"...
January 13, 2018: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29330460/enhanced-skeletal-muscle-ribosome-biogenesis-yet-attenuated-mtorc1-and-ribosome-biogenesis-related-signalling-following-short-term-concurrent-versus-single-mode-resistance-training
#4
Jackson J Fyfe, David J Bishop, Jonathan D Bartlett, Erik D Hanson, Mitchell J Anderson, Andrew P Garnham, Nigel K Stepto
Combining endurance training with resistance training (RT) may attenuate skeletal muscle hypertrophic adaptation versus RT alone; however, the underlying mechanisms are unclear. We investigated changes in markers of ribosome biogenesis, a process linked with skeletal muscle hypertrophy, following concurrent training versus RT alone. Twenty-three males underwent eight weeks of RT, either performed alone (RT group, n = 8), or combined with either high-intensity interval training (HIT+RT group, n = 8), or moderate-intensity continuous training (MICT+RT group, n = 7)...
January 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29328868/oral-sciences-phd-program-enrollment-graduates-and-placement-1994-to-2016
#5
C R Herzog, D W Berzins, P DenBesten, R L Gregory, K M Hargreaves, R L W Messer, M Mina, M P Mooney, M L Paine, C Phillips, R B Presland, R G Quivey, F A Scannapieco, J F Sheridan, K K H Svoboda, P C Trackman, M P Walker, S G Walker, C Y Wang, J C C Hu
For decades, dental schools in the United States have endured a significant faculty shortage. Studies have determined that the top 2 sources of dental faculty are advanced education programs and private practice. Those who have completed both DDS and PhD training are considered prime candidates for dental faculty positions. However, there is no national database to track those trainees and no evidence to indicate that they entered academia upon graduation. The objective of this study was to assess outcomes of dental school-affiliated oral sciences PhD program enrollment, graduates, and placement between 1994 and 2016...
January 1, 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/29318730/mentorship-in-the-health-professions-a-review
#6
REVIEW
Annette Burgess, Christie van Diggele, Craig Mellis
BACKGROUND: The importance of mentorship within health care training is well recognised. It offers a means to further enhance workforce performance and engagement, promote learning opportunities and encourage multidisciplinary collaboration. There are both career and life benefits associated with mentorship, and it is increasingly recognised as a bidirectional process that benefits both mentors and mentees. Recently, mentoring has been considered an essential step in professional and personal development, particularly in the field of health care...
January 10, 2018: Clinical Teacher
https://www.readbyqxmd.com/read/29315579/muscle-molecular-adaptations-to-endurance-exercise-training-are-conditioned-by-glycogen-availability-a-proteomics-based-analysis-in-the-mcardle-mouse-model
#7
Carmen Fiuza-Luces, Alejandro Santos-Lozano, Francisco Llavero, Rocío Campo, Gisela Nogales-Gadea, Jorge Díez Bermejo, Carlos Balandrón, África González-Murillo, Joaquín Arenas, Miguel A Martín, Antoni L Andreu, Tomàs Pinós, Beatriz G Gálvez, Juan A López, Jesús Vázquez, José L Zugaza, Alejandro Lucia
McArdle disease is an inborn disorder of skeletal muscle glycogen metabolism that results in blockade of glycogen breakdown due to mutations in the myophosphorylase gene. We recently developed a mouse model carrying the homozygous p.R50X common human mutation (McArdle mouse), facilitating the study of how glycogen availability affects muscle molecular adaptations to endurance exercise training. Using quantitative differential analysis by liquid chromatography with tandem-mass spectrometry, we analysed the quadriceps muscle proteome of 16-week-old McArdle (n = 5) and wild-type (WT) (n = 4) mice previously subjected to 8-week moderate-intensity treadmill training or to an equivalent control (no training) period...
January 7, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29311110/long-lasting-in-vivo-effects-of-the-cannabinoid-cb1-antagonist-am6538
#8
Carol A Paronis, Girish R Chopda, Kiran Vemuri, Ani S Zakarian, Alexandros Makriyannis, Jack Bergman
AM6538 is a cannabinoid antagonist that binds CB1 receptors expressed in HEK-293 cells in a wash-resistant manner. The effects of AM6538 in live animals has not previously been established. We characterized the antagonist effects of AM6538 in male mice, using a warm-water tail-withdrawal assay, and in male squirrel monkeys trained to discriminate the CB1 agonist AM4054 from vehicle. The cannabinoid agonists WIN 55,212, Δ9-tetrahydrocannabinol (THC), and AM4054 all produced 100% maximum possible antinociceptive effects in mice following vehicle pretreatment...
January 8, 2018: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/29307759/endurance-training-reduces-exercise-induced-acidosis-and-improves-muscle-function-in-a-mouse-model-of-sickle-cell-disease
#9
Benjamin Chatel, Laurent A Messonnier, Quentin Barge, Christophe Vilmen, Philippe Noirez, Monique Bernard, Vincent Pialoux, David Bendahan
Sickle cell disease (SCD) mice (Townes model of SCD) presented exacerbated exercise-induced acidosis and fatigability as compared to control animals. We hypothesize that endurance training could represent a valuable approach to reverse these muscle defects. Endurance-trained HbAA (HbAA-END, n=10), HbAS (HbAS-END, n=11) and HbSS (HbSS-END, n=8) mice were compared to their sedentary counterparts (10 HbAA-SED, 10 HbAS-SED and 9 HbSS-SED mice) during two rest - exercise - recovery protocols during which muscle energetics and function were measured...
November 28, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29307152/the-effects-of-10-week-core-stability-training-on-balance-in-women-with-multiple-sclerosis-according-to-expanded-disability-status-scale-a-single-blinded-randomized-controlled-trial
#10
Banafsheh Amiri, Mansour Sahebozamani, Behnaz Sedighi
AIM: The effect of 10-week core stability training (CST) program on balance in women with relapsing-remitting Multiple Sclerosis (MS) according to Expanded Disability Status Scale (EDSS) score. METHODS: Sixty-nine MS women were randomly assigned into two groups as the intervention group and the control group. These groups were categorized into three subgroups according to the EDSS as follows: subgroup A (EDSS 2.5 to 3.5), subgroup B (EDSS 3.5 to 4.5), and subgroup C (EDSS 4...
January 2, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29305709/influence-of-physical-activity-on-the-immune-system-in-breast-cancer-patients-during-chemotherapy
#11
Thorsten Schmidt, Walter Jonat, Daniela Wesch, Hans-Heinrich Oberg, Sabine Adam-Klages, Lisa Keller, Christoph Röcken, Christoph Mundhenke
PURPOSE: Physical activity can impact the immune system in different ways, e.g. by alteration of the humoral and cellular immune response. Physical activity at medium intensity enhances numbers of cytotoxic T cells, NK cells and macrophages in healthy people. The aim of this study was to compare the effects of endurance and resistance training on the immune system in breast cancer patients during adjuvant chemotherapy. METHODS: In a prospective, controlled and randomized intervention exploratory trial, 12-week supervised endurance or resistance training were compared with usual care twice a week...
January 5, 2018: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29299224/the-effectiveness-of-functional-electrical-stimulation-fes-in-on-off-mode-for-enhancing-the-cycling-performance-of-team-phoenix-at-2016-cybathlon
#12
Kenry Wc Leung, Raymond Ky Tong, Xiaojun Wang, Ginny Ty Lee, Peter Mk Pang, H W Wai, H C Leung
In this study we designed a Functional Electrical Stimulation (FES) trike for a female subject with spinal cord injury to exercise her lower limbs and improve her lower limb muscle condition for attending the 2016 Cybathlon FES bike competition. Our FES pilot was the only female participant, in the FES cycling competition and she rode for Team Phoenix from the Chinese University of Hong Kong. Due to the weakness of muscles in the lower limb of the subject, and due to scoliosis over her thoracolumbar aéra, the mechanical structure of the trike had to be tailor-made to ensure she sat on the bike in a safe and secure position...
December 5, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29299221/cycle-training-using-implanted-neural-prostheses-team-cleveland
#13
John McDaniel, Lisa M Lombardo, Kevin M Foglyano, Paul D Marasco, Ronald J Triolo
Recently our laboratory team focused on training five individuals with complete spinal cord injuries for an overground FES bike race in the 2016 Cybathlon held in Zurich Switzerland. A unique advantage team Cleveland had over other teams was the use of implanted pulse generators that provide more selective activation of muscles compared to standard surface stimulation. The advancements in muscle strength and endurance and ultimately cycling power our pilots made during this training period helped propel our competing pilot to win gold at the Cybathlon and allowed our pilots to ride their bikes outside within their communities...
December 5, 2017: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29290201/a-definition-of-family-medicine-and-general-practice
#14
M Jawad Hashim
Definitions of general practice and family medicine have tended to be difficult to understand. We propose a new definition that is brief and clear. General practice / family medicine is defined as the medical specialty that manages common and long-term illnesses in children and adults, focusing on overall health and well-being. The definition should be followed by local examples of diseases within the scope of primary care such as asthma, diabetes as well as end-of-life care. This definition is based on the concept of common illnesses, reflecting the reality that family physicians manage most health conditions in a community...
January 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29289581/physical-exercise-improves-strength-balance-mobility-and-endurance-in-people-with-cognitive-impairment-and-dementia-a-systematic-review
#15
Freddy Mh Lam, Mei-Zhen Huang, Lin-Rong Liao, Raymond Ck Chung, Timothy Cy Kwok, Marco Yc Pang
QUESTION: Does physical exercise training improve physical function and quality of life in people with cognitive impairment and dementia? Which training protocols improve physical function and quality of life? How do cognitive impairment and other patient characteristics influence the outcomes of exercise training? DESIGN: Systematic review with meta-analysis of randomised trials. PARTICIPANTS: People with mild cognitive impairment or dementia as the primary diagnosis...
December 27, 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/29288068/regular-exercisers-have-stronger-pelvic-floor-muscles-than-non-regular-exercisers-at-midpregnancy
#16
Kari Bø, Marie Ellstrøm Engh, Gunvor Hilde
BACKGROUND: Today, all healthy pregnant women are encouraged to be physically active throughout pregnancy, with recommendations to participate in at least 30 min of aerobic activity on most days of the week, in addition to perform strength training of the major muscle groups 2-3 days per week, and also pelvic floor muscle training. There is, however, an ongoing debate whether general physical activity enhances or declines pelvic floor muscle function. OBJECTIVES: To compare vaginal resting pressure, pelvic floor muscle strength and endurance in regular exercisers (exercise ≥ 30 minutes ≥ 3 times per week) and non-exercisers at mid-pregnancy...
December 26, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29287284/potential-relationship-between-passive-plantar-flexor-stiffness-and-running-performance
#17
Hiromasa Ueno, Tadashi Suga, Kenji Takao, Takahiro Tanaka, Jun Misaki, Yuto Miyake, Akinori Nagano, Tadao Isaka
The present study aimed to determine the relationship between passive stiffness of the plantar flexors and running performance in endurance runners. Forty-eight well-trained male endurance runners and 24 untrained male control subjects participated in this study. Plantar flexor stiffness during passive dorsiflexion was calculated from the slope of the linear portion of the torque-angle curve. Of the endurance runners included in the present study, running economy in 28 endurance runners was evaluated by measuring energy cost during three 4-min trials (14, 16, and 18 km/h) of submaximal treadmill running...
December 29, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29284664/lysophosphatidic-acid-acyltransferase-3-incorporates-docosahexaeneoic-acid-into-skeletal-muscle-cell-membranes-and-is-upregulated-by-ppar%C3%AE-activation
#18
William J Valentine, Suzumi M Tokuoka, Daisuke Hishikawa, Yoshihiro Kita, Hideo Shindou, Takao Shimizu
Adaption of skeletal muscle to endurance exercise includes PPARδ- and AMP-activated protein kinase (AMPK) / PPARγ coactivator 1α (PGC1α) -mediated transcriptional responses that result in increased oxidative capacity and conversion of glycolytic to more oxidative fiber types. These changes are associated with whole-body metabolic alterations including improved glucose handling and resistance to obesity. Increased docosahexaenoic acid (DHA; 22:6n-3) content in phosphatidylcholine (PC) and phosphatidylethanolamine (PE) is also reported in endurance exercise-trained glycolytic muscle; however, the DHA-metabolizing enzymes involved and biological significance of the enhanced DHA content are unknown...
December 28, 2017: Journal of Lipid Research
https://www.readbyqxmd.com/read/29284165/lactate-threshold-as-a-measure-of-aerobic-metabolism-in-resistance-exercise
#19
Raúl Domínguez, José Luis Maté-Muñoz, Noemí Serra-Paya, Manuel Vicente Garnacho-Castaño
In resistance training, load intensity is usually calculated as the percentage of a maximum repetition (1RM) or maximum number of possible repetitions (% of 1RM). Some studies have proposed a lactate threshold (LT) intensity as an optimal approach for concurrent training of cardiorespiratory endurance and muscle strength, as well as an alternative in resistance training. The objective of the present study was to analyze the results obtained in research evaluating the use of LT in resistance training. A keyword and search tree strategy identified 14 relevant articles in the Dialnet, Elsevier, Medline, Pubmed, Scopus and Web of Science databases...
December 28, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29283930/a-comparison-of-the-effects-of-endurance-training-on-alternate-days-and-on-consecutive-four-days-each-week-for-eight-weeks-on-the-abundance-of-pgc-1%C3%AE-camkii-nrf-1-mttfa-and-coxiv-proteins-in-rat-skeletal-muscle
#20
Jiwen Qiu, Liping Huang, Allan J Davie, Shi Zhou
The aim of this study was to compare the effects of two training protocols, training on alternate days (A) or on consecutive four days followed by three days of rest in each week (C) for eight weeks, on selected proteins involved in the biogenesis and function of mitochondria in skeletal muscle. Eighty male SD rats were randomly allocated into 10 groups (n=8 each), including Pre and Post control groups, and A or C training groups with 8, 16, 24 and 32 training sessions, respectively. The vastus lateralis and soleus muscle samples were obtained 24 hours after the last training session, or at rest for the controls...
December 27, 2017: Journal of Strength and Conditioning Research
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