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https://www.readbyqxmd.com/read/29777633/hypertrophic-effect-of-inhaled-beta-2-agonist-with-and-without-concurrent-exercise-training-a-randomized-controlled-trial
#1
Søren Jessen, Johan Onslev, Anders Lemminger, Vibeke Backer, Jens Bangsbo, Morten Hostrup
INTRODUCTION: Due to a high prevalence of asthma and exercise-induced bronchoconstriction in elite athletes, there is a high use of beta2 -adrenoceptor agonists (beta2 -agonists) in the athletic population. While anabolic in rodents, no study has been able to detect hypertrophy in humans after chronic beta2 -agonist inhalation. METHODS: We investigated if inhaled beta2 -agonist, terbutaline, alters body composition and metabolic rate with and without concurrent exercise training in healthy young men...
May 19, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29777386/substrate-metabolism-during-ironman-triathlon-different-horses-on-the-same-courses
#2
Ed Maunder, Andrew E Kilding, Daniel J Plews
Ironman triathlons are ultra-endurance events of extreme duration. The performance level of those competing varies dramatically, with elite competitors finishing in ~ 8:00:00, and lower performing amateurs finishing in ~ 14-15:00:00. When applying appropriate values for swimming, cycling and running economies to these performance times, it is demonstrated that the absolute energy cost of these events is high, and the rate of energy expenditure increases in proportion with the athlete's competitive level...
May 18, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29776425/combined-application-of-latissimus-dorsi-myocutaneous-flap-and-iliac-bone-flap-in-the-treatment-of-chronic-osteomyelitis-of-the-lower-extremity
#3
Jihui Ju, Lei Li, Rong Zhou, Ruixing Hou
BACKGROUND: To evaluate the clinical efficacy and safety of latissimus dorsi myocutaneous flap (stage I) combined with iliac bone flap (stage II) in the treatment of chronic osteomyelitis of the lower extremity. METHODS: Clinical data of 18 patients undergoing latissimus dorsi myocutaneous flap in combination with iliac bone flap grafting were retrospectively analyzed. Among them, 2 patients developed chronic osteomyelitis of the lower segment of the femur, 4 were diagnosed with chronic osteomyelitis of the tibial plateau, and 12 with chronic osteomyelitis of the lower segment of the tibia...
May 18, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29773412/athlete-s-heart-is-the-morganroth-hypothesis-obsolete
#4
Mark J Haykowsky, T Jake Samuel, Michael D Nelson, Andre La Gerche
In 1975, Morganroth and colleagues reported that the increased left ventricular (LV) mass in highly trained endurance athletes versus nonathletes was primarily due to increased end-diastolic volume while the increased LV mass in resistance trained athletes was solely due to an increased LV wall thickness. Based on the divergent remodelling patterns observed, Morganroth and colleagues hypothesised that the increased "volume" load during endurance exercise may be similar to that which occurs in patients with mitral or aortic regurgitation while the "pressure" load associated with performing a Valsalva manoeuvre (VM) during resistance exercise may mimic the stress imposed on the heart by systemic hypertension or aortic stenosis...
May 1, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29769816/the-effect-of-two-different-concurrent-training-programs-on-strength-and-power-gains-in-highly-trained-individuals
#5
Henrik Petré, Pontus Löfving, Niklas Psilander
The effects of concurrent strength and endurance training have been well studied in untrained and moderately-trained individuals. However, studies examining these effects in individuals with a long history of resistance training (RT) are lacking. Additionally, few studies have examined how strength and power are affected when different types of endurance training are added to an RT protocol. The purpose of the present study was to compare the effects of concurrent training incorporating either low-volume, high-intensity interval training (HIIT, 8-24 Tabata intervals at ~150% of VO2max ) or high-volume, medium-intensity continuous endurance training (CT, 40-80 min at 70% of VO2max ), on the strength and power of highly-trained individuals...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29767544/the-aerobic-resistance-inspiratory-muscle-training-hypothesis-in-heart-failure
#6
Ioannis D Laoutaris
Evidence from large multicentre exercise intervention trials in heart failure patients, investigating both moderate continuous aerobic training and high intensity interval training, indicates that the 'crème de la crème' exercise programme for this population remains to be found. The 'aerobic/resistance/inspiratory (ARIS) muscle training hypothesis in heart failure' is introduced, suggesting that combined ARIS muscle training may result in maximal exercise pathophysiological and functional benefits in heart failure patients...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29765327/cardiovascular-adaptive-homeostasis-in-exercise
#7
Kelvin J A Davies
Adaptive Homeostasis has been defined as, "The transient expansion or contraction of the homeostatic range in response to exposure to sub-toxic, non-damaging, signaling molecules or events, or the removal or cessation of such molecules or events." (Davies, 2016). I propose that one of the most significant examples of adaptive homeostasis may be the adaptation of the cardiovascular system to exercise training. In particular, endurance type training involves the generation of increased levels of free radicals such as ubisemiquinone, superoxide, nitric oxide, and other (non-radical) reactive oxygen species such as hydrogen peroxide (H2 O2 ), in a repetitive manner, typically several times per week...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29765176/impairments-of-postural-control-functional-performance-and-strength-in-morbidly-obese-patients-awaiting-bariatric-surgery-in-comparison-to-healthy-individuals
#8
Max Lennart Eckstein, Jimmy Bradley Lawrence, Christoph Otto, Peggy Kotsch, Janin Messerschmidt, Richard Michael Bracken, Othmar Moser
[Purpose] There is a lack of information evaluating specific markers of performance in patients awaiting bariatric surgery. We aimed to assess the postural control, functional performance, strength and endurance performance for morbidly obese patients awaiting bariatric surgery compared to lean controls. [Subjects and Methods] All parameters were assessed by modified Y-balance test, timed-up-and-go-test, maximum strength testing on resistance exercise equipment and cardio-pulmonary exercise testing on a cycle ergometer in 10 morbidly obese patients awaiting bariatric surgery and 10 age- and sex-matched lean controls...
May 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29764393/telerehabilitation-versus-traditional-centre-based-pulmonary-rehabilitation-for-people-with-chronic-respiratory-disease-protocol-for-a-randomised-controlled-trial
#9
Narelle S Cox, Christine F McDonald, Jennifer A Alison, Ajay Mahal, Richard Wootton, Catherine J Hill, Janet Bondarenko, Heather Macdonald, Paul O'Halloran, Paolo Zanaboni, Ken Clarke, Deidre Rennick, Kaye Borgelt, Angela T Burge, Aroub Lahham, Bruna Wageck, Hayley Crute, Pawel Czupryn, Amanda Nichols, Anne E Holland
BACKGROUND: Pulmonary rehabilitation is an effective therapeutic intervention for people with chronic respiratory disease. However, fewer than 5% of eligible individuals receive pulmonary rehabilitation on an annual basis, largely due to limited availability of services and difficulties associated with travel and transport. The Rehabilitation Exercise At Home (REAcH) study is an assessor-blinded, multi-centre, randomised controlled equivalence trial designed to compare the efficacy of home-based telerehabilitation and traditional centre-based pulmonary rehabilitation in people with chronic respiratory disease...
May 15, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29762540/the-role-of-peroxisome-proliferator-activated-receptors-and-their-transcriptional-coactivators-gene-variations-in-human-trainability-a-systematic-review
#10
REVIEW
Miroslav Petr, Petr Stastny, Adam Zajac, James J Tufano, Agnieszka Maciejewska-Skrendo
BACKGROUND: The peroxisome proliferator-activated receptors ( PPARA , PPARG , PPARD ) and their transcriptional coactivators' ( PPARGC1A , PPARGC1B ) gene polymorphisms have been associated with muscle morphology, oxygen uptake, power output and endurance performance. The purpose of this review is to determine whether the PPARs and/or their coactivators' polymorphisms can predict the training response to specific training stimuli. METHODS: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta Analyses, a literature review has been run for a combination of PPARs and physical activity key words...
May 15, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29761269/effects-of-running-a-marathon-on-irisin-concentration-in-men-aged-over-50
#11
Paweł Jóźków, Dawid Koźlenia, Katarzyna Zawadzka, Marek Konefał, Paweł Chmura, Katarzyna Młynarska, Michał Kosowski, Marek Mędraś, Jan Chmura, Piotr Ponikowski, Jacek Daroszewski
Our aim was to verify whether running a marathon is associated with changes in irisin concentration in healthy, endurance-trained men. In an observational study, we assessed baseline biochemical and fitness parameters of 28 middle-aged runners (mean ± SD age, BMI, VO2max : 58 ± 8 years; 24.5 ± 3 kg/m2 ; 51.1 ± 1.7 ml/kg/min). We evaluated irisin before, immediately after, and 7 days after the marathon. Irisin concentration decreased from a baseline value of 639 ± 427 to 461 ± 255 ng/ml immediately after the marathon (p < 0...
May 14, 2018: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29760853/emergency-physicians-at-war
#12
REVIEW
Andrew E Muck, Melissa Givens, Vikhyat S Bebarta, Phillip E Mason, Craig Goolsby
Operation Enduring Freedom (OEF-A) in Afghanistan and Operation Iraqi Freedom (OIF) represent the first major, sustained wars in which emergency physicians (EPs) fully participated as an integrated part of the military's health system. EPs proved invaluable in the deployments, and they frequently used the full spectrum of trauma and medical care skills. The roles EPs served expanded over the years of the conflicts and demonstrated the unique skill set of emergency medicine (EM) training. EPs supported elite special operations units, served in medical command positions, and developed and staffed flying intensive care units...
May 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29759716/atrial-fibrillation-in-athletes-a-lesson-in-the-virtue-of-moderation
#13
REVIEW
N A Mark Estes, Christopher Madias
Although the cardiovascular benefits of moderate exercise are well established, there is growing epidemiological support for the notion that high-intensity endurance athletics increases the risk of atrial fibrillation (AF). There are many gaps in evidence related to epidemiology and mechanisms of AF in endurance athletes. The proposed pathophysiological mechanisms include alterations of autonomic tone, electrical remodeling, anatomical remodeling, fibrosis, and inflammation. Clinical management of the athlete with AF often includes a period of decreased frequency, intensity, and duration of exercise with assessment for improvement in AF recurrence...
September 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29757049/prevalence-of-indicators-of-low-energy-availability-in-elite-female-sprinters
#14
Jennifer Sygo, Alexandra M Coates, Erik Sesbreno, Margo L Mountjoy, Jamie F Burr
Low energy availability (LEA), and subsequent relative energy deficiency in sport (RED-S), has been observed in endurance, aesthetic, and team sport athletes, with limited data on prevalence in athletes in short-burst activities such as sprinting. We examined prevalence of signs and symptoms of LEA in elite female sprinters at the start of the training season (PRE), and at the end of a 5-month indoor training period (POST). Four of 13 female sprinters (31%) presented at PRE testing with at least one primary (amenorrhea, low BMD, low FSH, LH, or estradiol, RMR ≤ 29kcal/kg FFM, Low Energy Availability in Females Questionnaire (LEAF-Q) score ≥8) and one secondary indicator of LEA (fasting blood glucose < 4mmol/L, free triiodothyronine < 3...
May 14, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29757047/development-and-implementation-of-a-nutrition-knowledge-questionnaire-for-ultra-endurance-athletes
#15
Claire Blennerhassett, Lars R McNaughton, Lorcan Cronin, S Andy Sparks
The nutritional intake of ultra-endurance athletes is often poorly matched with the requirements of the sport. Nutrition knowledge is a mediating factor to food choice that could correct such imbalances. Therefore, the purpose of this study was to develop and validate a questionnaire to assess the nutrition knowledge of ultra-endurance athletes. Nutritional knowledge was assessed using a modified sports nutrition questionnaire (ULTRA-Q). Four independent assessors with specialist sports nutrition knowledge confirmed the content validity of the ULTRA-Q...
May 14, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29753800/effect-of-sexual-intercourse-on-lower-extremity-muscle-force-in-strength-trained-men
#16
Leah M Valenti, Claudia Suchil, Gabriel Beltran, Roman C Rogers, Emily A Massey, Todd A Astorino
BACKGROUND: Sex has been deemed taboo for athletic performance going back to ancient Rome and Greece, as the act of sex was thought to promote ease and a sense of relaxation. AIM: This study examined the effect of sexual intercourse completed 12 hours before a bout of isokinetic dynamometry on muscle force production in strength-trained men. METHODS: 12 Healthy physically active men (age = 25.6 ± 3.8 years) who were sexually active participated in this study...
May 9, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29749646/left-and-right-ventricular-morphology-and-function-in-athletes-with-elevated-pulmonary-systolic-arterial-pressure
#17
Oana Mirea, Oana M Corîci, Octavian Istrătoaie, Ionuț Donoiu, Maria Iancău, Constantin Militaru
OBJECTIVES: The objective of the study was to evaluate the prevalence and potential impact of elevated pulmonary arterial systolic pressure (PASP) on left and right cardiac morphology and function in young elite athletes. METHODS: In total, 85 professional athletes (40 endurance, 20 strength, and 25 mixed training, mean age 17.8 ± 4.0) and 50 sedentary controls (mean age 18.6 ± 3.3) underwent transthoracic echocardiographic examination. Two-dimensional measurements of the right (RV) and left ventricle (LV) were obtained...
May 11, 2018: Echocardiography
https://www.readbyqxmd.com/read/29749641/antioxidant-rich-foods-and-response-to-altitude-training-a-randomized-controlled-trial-in-elite-endurance-athletes
#18
Anu Elisa Koivisto, Gøran Paulsen, Ingvild Paur, Ina Garthe, Espen Tønnessen, Truls Raastad, Nasser Ezzatkhah Bastani, Jostein Hallén, Rune Blomhoff, Siv Kjølsrud Bøhn
High doses of isolated antioxidant supplements such as vitamin C and E, have demonstrated the potential to blunt cellular adaptations to training It is, however, unknown whether intake of high doses of antioxidants from foods has similar effects. Hence, the aim of the study was to investigate whether intake of antioxidant-rich foods affects adaptations to altitude training in elite athletes. In a randomized controlled trial, 31 national team endurance athletes (23 ± 5 years), ingested antioxidant-rich foods (n=16) or eucaloric control foods (n=15) daily during a 3-week altitude training camp (2320 m)...
May 11, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29748195/does-high-intensity-endurance-training-increase-the-risk-of-atrial-fibrillation-a-longitudinal-study-of-left-atrial-structure-and-function
#19
Mildred A Opondo, Norman Aiad, Matthew A Cain, Satyam Sarma, Erin Howden, Douglas A Stoller, Jason Ng, Pieter van Rijckevorsel, Michinari Hieda, Takashi Tarumi, M Dean Palmer, Benjamin D Levine
BACKGROUND: Exercise mitigates many cardiovascular risk factors associated with atrial fibrillation. Endurance training has been associated with atrial structural changes which can increase the risk for atrial fibrillation. The dose of exercise training required for these changes is uncertain. We sought to evaluate the impact of exercise on left atrial (LA) mechanical and electrical function in healthy, sedentary, middle-aged adults. METHODS: Sixty-one adults (52±5 years) were randomized to either 10 months of high-intensity exercise training or yoga...
May 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29746639/branched-chain-amino-acids-are-the-primary-limiting-amino-acids-in-the-diets-of-endurance-trained-men-after-a-bout-of-prolonged-exercise
#20
Hiroyuki Kato, Katsuya Suzuki, Makoto Bannai, Daniel R Moore
Background: The indicator amino acid oxidation (IAAO) method estimates the protein intake required to maximize whole-body protein synthesis and identify the daily protein requirement in a variety of populations. However, it is unclear whether the greater requirements for endurance athletes previously determined by the IAAO reflect an increased demand for all or only some amino acids. Objective: The aim of this study was to determine the primary rate-limiting amino acids in endurance-trained athletes after prolonged exercise, by measuring the oxidation of ingested [1-13C]phenylalanine in response to variable amino acid intake...
May 9, 2018: Journal of Nutrition
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