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triamcinolone oral prednisolone

Yutaka Momota, Junya Yasuda, Nobuaki Arai, Masami Yamamoto, Hisashi Yoshimura, Mitsutaka Ikezawa, Shuji Suzuki, Kimimasa Takahashi, Toshinori Sako
CASE SUMMARY: A 14-year-old female spayed cat was referred for recurrent otitis externa and unusual proliferative lesions in both ear canals. The affected pinnae and external ear canals were covered with large reddish-to-dark-brown verrucous and necrotic tissue. Friable material and exudates occluded both ear canals. Proliferative lesions developed in both ears 2-3 weeks before referral. The histopathological diagnosis from two biopsies obtained from the friable materials with endoscopic biopsy forceps was proliferative and necrotising otitis externa (PNOE)...
January 2017: JFMS open reports
Tomohiro Kadota, Tomonori Yano, Tomoji Kato, Maomi Imajoh, Masaaki Noguchi, Hiroyuki Morimoto, Shozo Osera, Yusuke Yoda, Yasuhiro Oono, Hiroaki Ikematsu, Atsushi Ohtsu, Kazuhiro Kaneko
Background and study aims: One of the major complications after endoscopic resection (ER) for large superficial esophageal squamous cell carcinoma (ESCC) is benign esophageal stricture, which can reduce quality of life even if ESCC achieves a cure without organ resection. Recently, steroid administration has been reported as a prophylactic treatment to prevent esophageal strictures. This retrospective study evaluated the stricture rate according to the different width of mucosal defects due to ER and compared it to that seen with prophylactic steroid administration...
December 2016: Endoscopy International Open
Ryuya Hashimoto, Michihiro Uchiyama, Takatoshi Maeno
BACKGROUND: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare, highly malignant, extranodal lymphoma that preferentially infiltrates into subcutaneous adipose tissue. No case of SPTCL with the earliest symptoms occurring in the eye region has been reported. We report a case of SPTCL complicated by eyelid swelling. CASE PRESENTATION: A 19-year-old Japanese man presented with worsening left eyelid swelling. The patient's best-corrected visual acuity (BCVA) was 0...
July 20, 2016: BMC Ophthalmology
Muzaffer Kırıs, Togay Muderris, Gökhan Yalçıner, Sami Bercin, Ergun Sevil, Fatih Gul
OBJECTIVES/HYPOTHESIS: Local and systemic steroid treatment is the mainstay of therapy for nasal polyposis. This study aims to evaluate the safety and effectiveness of intrapolyp steroid injection on nasal polyposis and to compare the outcomes with short-term oral steroid treatment. STUDY DESIGN: Prospective, randomized, controlled endoscopic clinical trial. METHODS: Ninety patients with nasal polyps were randomly assigned in a 1:1 ratio to receive oral prednisolone 1 mg/kg/day, tapering by 5 mg/day, for 2 weeks, or to receive intrapolyp steroid injection (40 mg/mL triamcinolone, 1 mL) for up to five times with intervals of 1 week...
August 2016: Laryngoscope
Edward Chia-Cheng Lai, Cheng-Yang Hsieh, Monera B Wong, Swu-Jane Lin, Yang-Kuang Yang, Yea-Huei Kao Yang, Soko Setoguchi
PURPOSE: The study aimed to evaluate the comparative risk of oral ulcerations among antipsychotic medications. METHODS: We analyzed the National Health Insurance Research Database of Taiwan and included patients newly initiated with a single antipsychotic agent including haloperidol, sulpiride, olanzapine, quetiapine, risperidone, or amisulpride during 2002 to 2010. The outcome of interest was oral ulceration, defined by the presence diagnoses of stomatitis and mucositis, aphthous-like ulceration and oral burns, or dispensing of stomatological corticosteroids included triamcinolone, dexamethasone, hydrocortisone, and prednisolone...
February 2016: Pharmacoepidemiology and Drug Safety
Philip J Banerjee, Wen Xing, Catey Bunce, Malcolm Woodcock, Aman Chandra, Robert A H Scott, David G Charteris
PURPOSE: To investigate the feasibility of conducting a randomised controlled trial in patients undergoing pars plana vitrectomy surgery following open globe trauma (OGT). Additionally, to investigate the treatment effect and toxicity of intensive anti-inflammatory agents. METHODS: A 2-year, pilot, single-centre prospective, participant and surgeon-masked randomised controlled trial (RCT). Forty patients requiring vitrectomy surgery following OGT were randomised to either standard (control) or study treatment (adjuncts) in a 1:1 allocation ratio...
July 2016: British Journal of Ophthalmology
Jiang-Ping Yu, Yong-Jun Liu, Ya-Li Tao, Rong-Wei Ruan, Zhao Cui, Shu-Wen Zhu, Wang Shi
BACKGROUND: Endoscopic submucosal dissection (ESD) is rapidly becoming a favored method for removing early esophageal cancer, but the residual defects can be complicated with strictures that require repeated endoscopic balloon dilatation. Measures for preventing the post-ESD strictures have been sought. We conducted a systematic review of recent studies to evaluate these methods. METHODS: We searched MEDLINE, Cochrane Central Register of Controlled Trials, Embase, and Google Scholar until November 30, 2014...
December 2015: World Journal of Surgery
Ji Won Seo, Ho-Seok Sa
BACKGROUND: Periorbital lipogranuloma following autologous fat injection into the forehead for cosmetic facial augmentation is a recently described adverse outcome. Patients have typically been treated with surgical excision. This study evaluates the clinical characteristics of periorbital lipogranulomas, and the non-surgical treatment outcomes of these patients. METHODS: This is a noncomparative, interventional case series. A retrospective analysis of clinical data and radiographic images was performed of patients with periorbital lipogranuloma following autologous fat injection...
December 2015: Aesthetic Plastic Surgery
Shin-ya Kawashiri, Hideki Nakamura, Tomoki Origuchi, Kiyoshi Aoyagi, Atsushi Kawakami
A 60-year-old Japanese man developed a fever and dry cough. Although chest CT showed interstitial pneumonia, the primary disease was not revealed. The interstitial pneumonia was improved by treatment with oral prednisolone following methylprednisolone pulse therapy. After the discontinuation of prednisolone he developed swelling of the eyelids and polyarthralgia. Orbital magnetic resonance imaging showed enlargement of the bilateral lacrimal glands. (67)Gallium scintigraphy showed abnormal uptake of the bilateral lacrimal glands and pulmonary hilum...
2015: Nihon Rinshō Men'eki Gakkai Kaishi, Japanese Journal of Clinical Immunology
M Barret, B Beye, S Leblanc, F Beuvon, S Chaussade, F Batteux, F Prat
BACKGROUND: Extensive endoscopic resections for the treatment of early oesophageal neoplasia can result in fibro-inflammatory strictures that require repeated interventions, which significantly alter the patients' quality of life. AIMS: To review current evidence about the prevention of oesophageal strictures following endoscopic resections. METHODS: Systematic search of PubMed and Embase from inception to March 2015 using appropriate keywords...
July 2015: Alimentary Pharmacology & Therapeutics
A Baker, M Empson, R The, P Fitzharris
BACKGROUND: Immediate hypersensitivity to corticosteroids is reported to occur with an incidence of 0.1%. The largest previous case series reporting corticosteroid skin testing has seven patients. METHODS AND PATIENTS: We identified 23 patients (mean age 50 years, 65% female) from Auckland City Hospital who underwent skin testing (ST) for suspected corticosteroid hypersensitivity between July 2005 and April 2012. We performed a retrospective clinical case note review detailing clinical history of reaction, skin test results and subsequent management...
March 2015: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
Hiroyuki Shoji, Naoyuki Yamaguchi, Hajime Isomoto, Hitomi Minami, Kayoko Matsushima, Yuko Akazawa, Ken Ohnita, Fuminao Takeshima, Saburo Shikuwa, Kazuhiko Nakao
BACKGROUND: The expansion of the indications for endoscopic submucosal dissection (ESD) to include early gastric cancers has enabled extensive resection. However, post-ESD stenosis after large resections applied to the gastric cardia or pylorus is often difficult to manage. The aim of this study was to evaluate the benefit of oral prednisolone and triamcinolone injection for stenosis after gastric ESD. METHODS: Eight patients who underwent ESD for large neoplastic lesions that extended more than three-fourths of the luminal circumference were enrolled in this study...
March 2014: Annals of Translational Medicine
Sílvia Mendes, António Campos, Diana Beselga, Joana Campos, Arminda Neves
PURPOSE: This study aims to report a case of traumatic maculopathy in a 12-year-old male following blunt trauma in his left eye (LE) who presented 6 months after injury. METHODS: Retrospective and descriptive case report based on data from clinical records, patient observation and analysis of diagnostic tests. RESULTS: A previously healthy, 12-year-old male presented for a routine visit with complaints of a 2-month history of decreased visual acuity in his LE...
January 2014: Case Reports in Ophthalmology
Marcelo C Ventura, Bruna V Ventura, Camila V Ventura, Liana O Ventura, Tiago E Arantes, Walton Nosé
PURPOSE: To compare the outcomes of congenital cataract surgery using intraoperative intracameral triamcinolone versus postoperative oral prednisolone to modulate ocular inflammation. SETTING: Department of Congenital Cataract, Altino Ventura Foundation, Recife, Brazil. DESIGN: Randomized clinical trial. METHODS: Children younger than 2 years were randomly divided into 2 groups. The study group received an intraoperative intracameral injection of 1...
April 2014: Journal of Cataract and Refractive Surgery
Ru-Cheng Kuo, Hung-Pin Lin, Andy Sun, Yi-Ping Wang
BACKGROUND/PURPOSE: Erosive oral lichen planus (EOLP) is a T-cell-mediated inflammatory disease that is refractory to treat. This study tested whether local injection of triamcinolone acetonide plus oral administration of low- or medium-dose prednisolone could hasten the healing of EOLP lesions. METHODS: In this study, 50 EOLP patients were treated with local injection of Kenacort A (40 mg triamcinolone acetonide once weekly for 3 and 2 weeks for 30 major and 20 minor EOLP patients, respectively) plus oral administration of prednisolone (25-30 mg and 15-20mg of prednisolone once daily for 2 weeks for 30 major and 20 minor EOLP patients, respectively)...
April 2013: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Saroj K Rath, M Reenesh
Pemphigus is a group of autoimmune diseases characterized by formation of intraepithelial bullae in skin and the mucous membrane. Pemphigus vulgaris affects the oral mucosa in nearly all cases. Pemphigus vulgaris is characterized by auto antibodies directed against desmosome-associated protein antigens (desmoglein-3) found in epithelial and epidermal intercellular substance. We report here a case of pemphigus vulgaris of gingiva in an adult female patient at an early stage followed by dermatologic involvement...
October 2012: Journal of Indian Society of Periodontology
Philip J Banerjee, Malcolm G Woodcock, Catey Bunce, Robert Scott, David G Charteris
BACKGROUND: Eyes sustaining open globe trauma (OGT) is a group at high risk of severe visual impairment. Proliferative vitreoretinopathy (PVR) is the commonest cause of retinal redetachment in these eyes and is reported to occur in up to 45% of cases. Intensive anti-inflammatory agents have been shown to be effective at modifying experimental PVR and to be well tolerated clinically.The Adjuncts in Ocular Trauma (AOT) Trial was designed to investigate the benefits of using intensive anti-inflammatory agents (intravitreal and sub-Tenon's triamcinolone, oral flurbiprofen and guttae prednisolone 1...
2013: Trials
Hajime Isomoto, Naoyuki Yamaguchi, Hitomi Minami, Kazuhiko Nakao
Endoscopic resection of early esophageal cancer (EEC) is an established therapy in Japan and is increasingly becoming accepted and used regularly in other countries. Endoscopic submucosal dissection (ESD), an application of conventional endoscopic mucosal resection (EMR), has been developed to allow the resection of larger lesions in an en bloc manner; the earliest results so far have been promising even in EEC. ESD allows precise assessment of the histopathological curability of resected specimens, reducing local recurrence...
March 2013: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
Susannah Longmuir, Alina Dumitrescu, Young Kwon, H Culver Boldt, Sandy Hong
A 14-month-old boy with juvenile xanthogranuloma skin lesions presented with increased intraocular pressure, hyphema, anterior uveitis, iris mass, and a subconjunctival limbal mass of the right eye. He subsequently developed a subretinal mass in the left eye. The anterior uveitis resolved after 2 periocular injections of triamcinolone in addition to the administration of topical prednisolone and oral prednisone and methotrexate. The subretinal mass in the left eye also resolved during the course of 1 year. He developed a cataract in the right eye and underwent lensectomy with anterior vitrectomy...
December 2011: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Parisa Taravati, Deborah L Lam, Thellea Leveque, Russell N Van Gelder
PURPOSE OF REVIEW: To describe the epidemiology, pathogenesis, and recent developments in the diagnosis and management of postcataract surgery inflammation. RECENT FINDINGS: In patients with pre-existing uveitis, control of inflammation with topical and/or systemic therapy for 3 months preoperatively continues to be important in lessening the risk of postoperative inflammation and complications. During cataract surgery, intraocular lens selection in these patients is important...
January 2012: Current Opinion in Ophthalmology
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