keyword
https://read.qxmd.com/read/38513984/precision-in-norwood-shunt-sizing-single-ventricle-reconstruction-trial-public-dataset-analysis
#21
JOURNAL ARTICLE
Luisa Raga, Haleh Heydarian, David Winlaw, Huaiyu Zang, James F Cnota, Nicholas J Ollberding, Garick D Hill
BACKGROUND: Morbidity and mortality following the Norwood procedure remains high. Shunt size selection is not standardized and the impact of shunt size on outcomes is poorly understood. The Single Ventricle Reconstruction trial randomized infants to modified Blalock-Taussig-Thomas shunt (MBTTS) or right ventricle-to-pulmonary artery shunt (RVPAS) at the Norwood procedure. We assessed shunt size distribution and its association with postoperative outcomes. METHODS: We included 544 patients, excluding 5 with ambiguous shunt crossover data...
March 19, 2024: Annals of Thoracic Surgery
https://read.qxmd.com/read/38489836/configuration-of-the-neo-aortic-root-after-chimney-reconstruction-in-the-norwood-procedure
#22
JOURNAL ARTICLE
Satoshi Asada, Shinichiro Oda, Yoshinobu Maeda, Shuhei Fujita, Hisayuki Hongu, Eijiro Yamashita, Hiroki Nakatsuji, Takashi Nagase, Rie Nakai, Takaaki Hayashi, Jin Ikarashi, Yasutaka Goto, Masaaki Yamagishi
OBJECTIVES: After staged reconstruction for hypoplastic left heart syndrome (HLHS), the neoaortic root tends to dilate, and the incidence of significant neoaortic valve insufficiency increases with time. This study aimed to evaluate the mid-term outcomes of the neoaortic root geometries and valve function after chimney reconstruction in the Norwood procedure. METHODS: Between 2013 and 2021, 20 consecutive patients who underwent chimney reconstruction during the Norwood procedure for HLHS and its variants in our institution were enrolled...
March 15, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/38484324/hormonal-contraception-and-risk-of-cardiometabolic-disease-in-women-with-hiv
#23
JOURNAL ARTICLE
Jamison Norwood, Cathy A Jenkins, Manasa Bhatta, Megan Turner, Aihua Bian, Jeffrey Nelson, Imani Ransby, Dana Hughes, John R Koethe, Timothy R Sterling, Bryan E Shepherd, Jessica L Castilho
Objective: We sought to determine the association of hormonal contraception (HC) and cardiometabolic outcomes among women with human immunodeficiency virus (HIV). Methods: We included women with HIV aged 18-45 years in clinical care in the Southeastern United States between 1998 and 2018. Oral and injectable HC use was captured from medication records. Our outcomes included incident cardiovascular/thrombotic disease (CVD) (atherosclerosis, hypertension, cerebrovascular disease, thrombosis, and heart failure) and incident metabolic disorders (diabetes, dyslipidemia, obesity, and non-alcoholic steatohepatitis)...
March 14, 2024: Journal of Women's Health
https://read.qxmd.com/read/38483198/cardiac-surgery-associated-acute-kidney-injury-in-neonates-undergoing-the-norwood-operation-retrospective-analysis-of-the-multicenter-neonatal-and-pediatric-heart-and-renal-outcomes-network-dataset-2015-2018
#24
JOURNAL ARTICLE
Rebecca A Bertrandt, Katja Gist, Denise Hasson, Huaiyu Zang, Garrett Reichle, Catherine Krawczeski, David Winlaw, David Bailly, Stuart Goldstein, David Selewski, Jeffrey Alten
OBJECTIVES: Cardiac surgery-associated acute kidney injury (CS-AKI) is associated with adverse outcomes. Single-center studies suggest that the prevalence of CS-AKI is high after the Norwood procedure, or stage 1 palliation (S1P), but multicenter data are lacking. DESIGN: A secondary analysis of the Neonatal and Pediatric Heart and Renal Outcomes Network (NEPHRON) multicenter cohort who underwent S1P. Using neonatal modification of Kidney Disease Improving Global Outcomes (KDIGO) criteria, perioperative associations between CS-AKI with morbidity and mortality were examined...
March 14, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/38469722/estimation-of-the-inferior-caval-vein-saturation-using-high-fidelity-non-invasive-haemodynamic-values-and-validation-of-modelled-estimates
#25
JOURNAL ARTICLE
Rohit S Loomba, Saul Flores, Juan S Farias, Enrique G Villarreal, Alex Constas
OBJECTIVES: Monitoring venous saturation allows identification of inadequate systemic oxygen delivery. The aim was to develop a model using non-invasive haemodynamic variables to estimate the inferior caval vein saturation and to determine its prognostic utility. METHODS: This is a single-centre, retrospective study. A Bayesian Pearson's correlation was conducted to model the inferior caval vein saturation. Next, a Bayesian linear regression was conducted for data from all the patients and from only those with parallel circulation...
March 12, 2024: Cardiology in the Young
https://read.qxmd.com/read/38465590/total-aortic-arch-and-neoaortic-root-replacement-following-stage-iii-palliation-for-hypoplastic-left-heart-syndrome
#26
JOURNAL ARTICLE
Sayar Kumar Munshi, Tommaso Generali, Arul Narayanan, Raul Jose Correia, Ramesh Kutty, Ram Dhannapuneni
Progressive dilatation of the neoaortic root and reconstructed aortic arch is a serious complication after the Norwood procedure. There are no clear guidelines on the management of this complex anatomy in the setting of single ventricle physiology, and the surgical treatment of such an entity remains anecdotal. We describe a successful surgical repair in a 15-year-old girl presenting with a severely dilated neoaortic root and aortic arch causing compression and narrowing of the left pulmonary artery after successful three-stage palliation for hypoplastic left heart syndrome...
March 11, 2024: World Journal for Pediatric & Congenital Heart Surgery
https://read.qxmd.com/read/38464553/failure-rates-of-nonoperative-management-of-low-grade-splenic-injuries-with-active-extravasation-an-eastern-association-for-the-surgery-of-trauma-multicenter-study
#27
JOURNAL ARTICLE
Kristen Spoor, John David Cull, Banan W Otaibi, Joshua P Hazelton, John Chipko, Jessica Reynolds, Sam Fugate, Claire Pederson, Linda B Zier, Lewis E Jacobson, Jamie M Williams, Thomas S Easterday, Saskya Byerly, Caleb Mentzer, Edward Hawke, Daniel C Cullinane, Julianne B Ontengco, Nikolay Bugaev, Madison LeClair, Pascal Udekwu, Cooper Josephs, Matthew Noorbaksh, James Babowice, Catherine Garrison Velopulos, Shane Urban, Anna Goldenberg, Gaby Ghobrial, John M Pickering, Steven D Quarfordt, Alia F Aunchman, Aimee K LaRiccia, Chance Spalding, Richard D Catalano, Jordan E Basham, Philip M Edmundson, Jeffry Nahmias, Erika Tay, Scott H Norwood, Katelyn Meadows, Yee Wong, Claire Hardman
OBJECTIVES: There is little evidence guiding the management of grade I-II traumatic splenic injuries with contrast blush (CB). We aimed to analyze the failure rate of nonoperative management (NOM) of grade I-II splenic injuries with CB in hemodynamically stable patients. METHODS: A multicenter, retrospective cohort study examining all grade I-II splenic injuries with CB was performed at 21 institutions from January 1, 2014, to October 31, 2019. Patients >18 years old with grade I or II splenic injury due to blunt trauma with CB on CT were included...
2024: Trauma Surgery & Acute Care Open
https://read.qxmd.com/read/38463144/delays-in-colorectal-cancer-screening-for-latino-patients-the-role-of-immigrant-healthcare-in-stemming-the-rising-global-incidence-of-colorectal-cancer
#28
Eleazar E Montalvan-Sanchez, Renato Beas, Ahmad Karkash, Ambar Godoy, Dalton Argean Norwood, Michael Dougherty
The significant global burden of colorectal cancer accentuates disparities in access to preventive healthcare in most low- and middle-income countries (LMICs) as well as large sections of underserved populations within high-income countries. The barriers to colorectal cancer screening in economically transitioning Latin America are multiple. At the same time, immigration from these countries to the USA continues to increase. This case highlights the delays in diagnosis experienced by a recent immigrant from a country with no established colorectal cancer screening program, to an immigrant population in the USA with similar poor screening coverage...
February 2024: Gastroenterology Research
https://read.qxmd.com/read/38459240/surgical-modulation-of-pulmonary-artery-shear-stress-a-patient-specific-cfd-analysis-of-the-norwood-procedure
#29
JOURNAL ARTICLE
Simbarashe G Chidyagwai, Michael S Kaplan, Christopher W Jensen, James S Chen, Reid C Chamberlain, Kevin D Hill, Piers C A Barker, Timothy C Slesnick, Amanda Randles
PURPOSR: This study created 3D CFD models of the Norwood procedure for hypoplastic left heart syndrome (HLHS) using standard angiography and echocardiogram data to investigate the impact of shunt characteristics on pulmonary artery (PA) hemodynamics. Leveraging routine clinical data offers advantages such as availability and cost-effectiveness without subjecting patients to additional invasive procedures. METHODS: Patient-specific geometries of the intrathoracic arteries of two Norwood patients were generated from biplane cineangiograms...
March 8, 2024: Cardiovascular Engineering and Technology
https://read.qxmd.com/read/38451966/factors-associated-with-early-onset-androgenetic-alopecia-a-scoping-review
#30
JOURNAL ARTICLE
Li-Ping Liu, Mary Adumo Wariboko, Xiao Hu, Zi-Han Wang, Qian Wu, Yu-Mei Li
BACKGROUND: Early-onset androgenetic alopecia (AGA) has been associated with various chronic conditions, including metabolic syndrome (MetS). Gaining a deep understanding of early-onset AGA may enable earlier intervention in individuals at high risks. This scoping review aims to explore the risk factors and etiology, associated conditions, and adverse effects on wellbeing in early-onset AGA. METHODS: Electronic literature searches were conducted in MEDLINE, EMBASE and CENTRIAL...
2024: PloS One
https://read.qxmd.com/read/38435192/effects-of-oil-pulling-and-chlorhexidine-mouth-rinse-on-the-force-decay-of-orthodontic-elastomeric-chains-a-comparative-in-vitro-study
#31
JOURNAL ARTICLE
Keerthana Sivaraman, Rajasekaran Ub, Neetika Prabu, Arun Deepak, Nagaland T, Anusha Sreedharan
BACKGROUND AND OBJECTIVES: Oil pulling is a traditional Indian folk remedy for maintaining oral hygiene among orthodontic patients. This study aimed to assess the effects of oil pulling and compare them with those of chlorhexidine (CHX) and distilled water on the force decay of elastomeric chains. METHODS: Twenty-one samples were tested in three groups. Each of these groups contained seven samples per group. The samples evaluated contained distilled water, 0.2% CHX, and sesame oil...
February 2024: Curēus
https://read.qxmd.com/read/38433570/survival-does-not-differ-by-annual-center-transplant-volume-a-pediatric-heart-transplant-society-registry-study
#32
JOURNAL ARTICLE
A Marion Ybarra, Alicia M Kamsheh, Matthew J O'Connor, Seth A Hollander, Maria Bano, Michelle Ploutz, Gabrielle Vaughn, Andrea Lambert, Michael Wallendorf, James Kirklin, Charles E Canter
BACKGROUND: There are conflicting data regarding the relationship between center volume and outcomes in pediatric heart transplantation. Previous studies have not fully accounted for differences in case mix, particularly in high-risk congenital heart disease (CHD) groups. We aimed to evaluate the relationship between center volume and outcomes using the Pediatric Heart Transplant Society (PHTS) Registry and explore how case mix may affect outcomes. METHODS: A retrospective cohort study of all pediatric patients in the PHTS Registry who received a heart transplant from 2009 to 2018 was performed...
March 2024: Pediatric Transplantation
https://read.qxmd.com/read/38410043/days-alive-and-out-of-hospital-for-children-born-with-single-ventricle-heart-disease
#33
JOURNAL ARTICLE
Cathlyn K Medina, Neel K Prabhu, Isaac S Alderete, Lauren E Parker, Hoe King Lim, Mary E Moya-Mendez, Lillian Kang, M Jay Campbell, Douglas M Overbey, Joseph W Turek, Nicholas D Andersen
BACKGROUND: This study describes the illness burden in the first year of life for children with single-ventricle heart disease, using the metric of days alive and out of hospital to characterize morbidity and mortality. METHODS: This is a retrospective single-centre study of single-ventricle patients born between 2005 and 2021 who had their initial operation performed at our institution. Patient demographics, anatomical details, and hospitalizations were extracted from our institutional single-ventricle database...
February 27, 2024: Cardiology in the Young
https://read.qxmd.com/read/38404131/mortality-and-heart-transplantation-after-hybrid-palliation-of-hypoplastic-left-heart-syndrome-a-systematic-review-and-meta-analysis
#34
REVIEW
Xander Jacquemyn, Tajinder P Singh, Jeffrey G Gossett, Konstantin Averin, Shelby Kutty, Liesl J Zühlke, Leila H Abdullahi, Aparna Kulkarni
BACKGROUND: Newborns with hypoplastic left heart syndrome (HLHS) who are considered at increased risk for death following Norwood/Sano surgery often undergo hybrid palliation (HP) as initial surgery. We aimed to compile the HP experience in HLHS and its variants and assess the rates of, and risk factors for, death and heart transplantation. METHODS: CINAHL, CINAHL PLUS, PubMed/MEDLINE, and SCOPUS were systematically searched for HP outcome studies of death or heart transplantation in HLHS between 1998 and 2022...
March 2024: World Journal for Pediatric & Congenital Heart Surgery
https://read.qxmd.com/read/38388965/increased-expression-of-cd70-in-relapsed-acute-myeloid-leukemia-after-hypomethylating-agents
#35
JOURNAL ARTICLE
Mario L Marques-Piubelli, Bijender Kumar, Rafet Basar, Siler Panowski, Surabhi Srinivasan, Kevin Norwood, Sacha Prashad, Victoria Szenes, Arun Balakumaran, Akanksha Arandhya, Wei Lu, Khaja Khan, Daniela Duenas, Salome McAllen, Javier A Gomez, Jared K Burks, Sunil Acharyal, Gautam Borthakur, Wei-Lien Wang, Wei Wang, Sa Wang, Luisa M Solis, David Marin, Katayoun Rezvani, May Daher, Francisco Vega
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. While induction chemotherapy leads to remission in most patients, a significant number will experience relapse. Therefore, there is a need for novel therapies that can improve remission rates in patients with relapsed and refractory AML. CD70 is the natural ligand for CD27 (a member of the TNF superfamily) and appears to be a promising therapeutic target. Consequently, there is considerable interest in developing chimeric antigen receptor (CAR) T-cell therapy products that can specifically target CD70 in various neoplasms, including AML...
February 22, 2024: Virchows Archiv: An International Journal of Pathology
https://read.qxmd.com/read/38383053/longitudinal-analysis-of-systemic-ventricular-function-and-atrioventricular-valve-function-after-the-norwood-procedure
#36
JOURNAL ARTICLE
Stefan Fetcu, Takuya Osawa, Frank Klawonn, Thibault Schaeffer, Christoph Röhlig, Helena Staehler, Chiara Di Padua, Paul Philipp Heinisch, Nicole Piber, Alfred Hager, Peter Ewert, Jürgen Hörer, Masamichi Ono
OBJECTIVES: To evaluate longitudinal systemic ventricular function and atrioventricular valve regurgitation in patients after the neonatal Norwood procedure. METHODS: Serial postoperative echocardiographic images before Fontan completion were assessed in neonates who underwent the Norwood procedure between 2001 and 2020. Ventricular function and atrioventricular valve regurgitation were compared between patients with modified Blalock-Taussig shunt and right ventricle to pulmonary artery conduit...
March 1, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/38382029/creating-a-multimedia-game-to-explore-nursing-specialties
#37
JOURNAL ARTICLE
Nikki R Smith, Vera Polyakova-Norwood
No abstract text is available yet for this article.
February 6, 2024: Nurse Educator
https://read.qxmd.com/read/38381948/intention-to-use-different-formulations-of-longer-acting-hiv-pre-exposure-prophylaxis-among-transgender-and-gender-expansive-individuals-the-roles-of-social-vulnerability-and-medical-mistrust
#38
JOURNAL ARTICLE
Phillip W Schnarrs, Julie Zuñiga, Gabrielle Benitez, Paul Fliedner, Aliza Norwood, Madeleine Croll, Liany D Serrano Oviedo, Jacey Buchorn, John Oeffinger, Rocky Lane, Emmett Schelling, Gin Pham, TreShaun Pate, Elizabeth M Arnold
In 2012, the Federal Drug Administration approved daily oral pre-exposure prophylaxis (PrEP) for HIV prevention in adults. Longer acting injectable PrEP (LA PrEP) has been approved and other formulations are in development. A successful LA PrEP rollout requires examining potential facilitators and barriers to PrEP uptake. Given that transgender and gender expansive (TGE) individuals experience more social vulnerability and higher levels of medical mistrust compared to other populations, examining the role of these two factors in LA PrEP uptake is important...
February 2024: AIDS Patient Care and STDs
https://read.qxmd.com/read/38378096/environmental-injustice-is-associated-with-poorer-asthma-outcomes-in-school-age-children-with-asthma-in-metropolitan-atlanta-georgia
#39
JOURNAL ARTICLE
Jocelyn R Grunwell, Abby D Mutic, Idil D Ezhuthachan, Carrie Mason, Mallory Tidwell, Cherish Caldwell, Jalicae Norwood, Sydney Zack, Natalie Jordan, Anne M Fitzpatrick
BACKGROUND: Environmental justice mandates that no person suffers disproportionately from environmental exposures. The Environmental Justice Index (EJI) provides an estimate of the environmental burden for each census tract but has not yet been utilized in asthma populations. OBJECTIVE: We hypothesized that children from census tracts with high environmental injustice determined by the EJI would have a greater burden of asthma exacerbations, poorer asthma control, and poorer lung function over 12 months...
February 18, 2024: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/38370294/knowledge-and-attitudes-on-contraception-and-reproductive-health-in-women-with-hiv
#40
JOURNAL ARTICLE
Anna Henricks, Samantha Singal, Dana Hughes, Sean Kelly, Jessica L Castilho, Jamison Norwood
BACKGROUND: For reasons not fully explained to date, contraception usage among women with HIV remains low. The aim of our study was to understand attitudes toward and lifetime use of contraception among women with HIV. METHODS: We administered an anonymous, community-informed, voluntary survey to cisgender, English-speaking women with HIV (≥18 years of age) at a Southern urban HIV clinic. It included multiple choice and Likert-scale questions on reproductive health...
February 2024: Open Forum Infectious Diseases
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