keyword
MENU ▼
Read by QxMD icon Read
search

CRAMP

keyword
https://www.readbyqxmd.com/read/29453587/trimorphic-extreme-clubfoot-deformities-and-their-management-by-triple-surgical-skin-expanders-dolar-dolarz-and-dolarz-e-evidence-based-mega-corrections-without-arthrodesis
#1
Rattan L Mittal
AIM/PURPOSE: Extreme congenital club foot deformities are common in developing countries, presenting at birth, persisting in children, adolescents and adults; as untreated/under-corrected by conservative and/or surgical means. Scores of confusing names exist in literature for such deformities with no good treatment available; mostly advocating unacceptable arthrodesis. The author researched this grey area for more than 40 years and successfully innovated improved surgical corrections, more acceptable to patients...
February 17, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29447434/alterations-in-melatonin-and-serotonin-signalling-in-the-colonic-mucosa-of-mice-with-dextran-sodium-sulfate-induced-colitis
#2
Sarah J MacEachern, Catherine M Keenan, Evangelia Papakonstantinou, Keith A Sharkey, Bhavik Anil Patel
BACKGROUND AND PURPOSE: Inflammatory bowel disease (IBD) is characterized by pain, bleeding, cramping and altered gastrointestinal (GI) function. Changes in mucosal serotonin (5-HT) signalling occur in animal models of colitis and in humans suffering from IBD. Melatonin is co-released with 5-HT from the mucosa and has a wide variety of actions in the GI tract. Here we examined how melatonin signalling is affected by colitis and determined how this relates to 5-HT signalling. EXPERIMENTAL APPROACH: Using electroanalytical approaches, we investigated how 5-HT release, reuptake and availability as well as melatonin availability are altered in dextran sodium sulfate (DSS)-induced colitis in mice...
February 15, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29440355/the-antimicrobial-peptide-cramp-is-essential-for-colon-homeostasis-by-maintaining-microbiota-balance
#3
Teizo Yoshimura, Mairi H McLean, Amiran K Dzutsev, Xiaohong Yao, Keqiang Chen, Jiaqiang Huang, Wanghua Gong, Jiamin Zhou, Yi Xiang, Jonathan H Badger, Colm O'hUigin, Vishal Thovarai, Lino Tessarollo, Scott K Durum, Giorgio Trinchieri, Xiu-Wu Bian, Ji Ming Wang
Commensal bacteria are critical for physiological functions in the gut, and dysbiosis in the gut may cause diseases. In this article, we report that mice deficient in cathelin-related antimicrobial peptide (CRAMP) were defective in the development of colon mucosa and highly sensitive to dextran sulfate sodium (DSS)-elicited colitis, as well as azoxymethane-mediated carcinogenesis. Pretreatment of CRAMP-/-mice with antibiotics markedly reduced the severity of DSS-induced colitis, suggesting CRAMP as a limiting factor on dysbiosis in the colon...
February 12, 2018: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/29438271/efficacy-of-misoprostol-before-diagnostic-hysteroscopy-in-postmenopausal-women-a-randomized-clinical-trial
#4
Fabiana Y Nakano, Daniela A Yela, Joao P L Pinto, Talita Riegas, Cristina L Benetti-Pinto, Adriana Orcesi Pedro, Lucia Helena Costa Paiva
OBJECTIVE: To evaluate pain and determine the efficacy of misoprostol, compared with placebo, for postmenopausal women before diagnostic hysteroscopy. METHODS: This randomized, double-blind, placebo-controlled clinical trial included 158 postmenopausal women who received either 200 μg of misoprostol or placebo through the vaginal route before diagnostic hysteroscopy (79 women/group). The primary outcome was pain assessment (presence and intensity) during the four steps of hysteroscopy: cervical grasping with a Pozzi tenaculum forceps immediately before hysteroscopy, during hysteroscopy, during performance of the endometrial biopsy, and postprocedure...
February 12, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29429768/are-senna-based-laxatives-safe-when-used-as-long-term-treatment-for-constipation-in-children
#5
Alejandra Vilanova-Sanchez, Alessandra C Gasior, Nicole Toocheck, Laura Weaver, Richard J Wood, Carlos A Reck, Andrea Wagner, Erin Hoover, Renae Gagnon, Jordon Jaggers, Tassiana Maloof, Onnalisa Nash, Charae Williams, Marc A Levitt
BACKGROUND AND AIM: Senna is a stimulant laxative commonly used by pediatricians, pediatric gastroenterologists, and pediatric surgeons. Many clinicians avoid Senna for reasons such as tolerance or side effects but this has little scientific justification. We recently found several patients we were caring for developed perineal blistering during the course of Senna treatment. Because of this we chose to review the literature to identify side effects in children taking this medication as well as to analyze our Center's experience with Senna's secondary effects...
January 31, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29428979/relationship-between-copper-iud-complications-and-ultrasonographic-findings
#6
Seyma Fadiloglu, B Dilbaz, E Fadiloglu, S Dilbaz
OBJECTIVE: Intrauterine device (IUD) is a widely used long-acting contraceptive method; however, the side-effects related to IUD may lead to method discontinuation. The aim of this study is to evaluate the relation between the most common side-effects of IUD use; mainly dysmenorrhea, menorrhaghia, pelvic cramping and the relation of these complications with the position of the IUD device within the cavity and uterine dimensions evaluated by transvaginal ultrasonography. MATERIAL AND METHOD: Two hundred and eighty-four patients who had Cu-T380A IUD insertion at the Family Planning Clinic of a tertiary health center were evaluated at insertion and 6 and 12 weeks after the insertion...
February 10, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29424318/the-significance-of-pain-in-chronic-venous-disease-and-its-medical-treatment
#7
Djordje Radak, Igor Atanasijevic, Mihailo Neskovic, Esma Isenovic
Chronic venous disease (CVeD) is a highly prevalent condition in the general population, and it has a significant impact on quality of life. While it is usually manifested by obvious signs, such as varicose veins and venous ulcers, other symptoms of the disease are less specific. Among the other symptoms, which include heaviness, swelling, muscle cramps and restless legs, pain is the symptom that most frequently compels CVeD patients to seek medical aid. However, there is a substantial discrepancy between pain severity and clinically detectable signs of CVeD, questioned by several opposing studies...
February 8, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29423776/full-recovery-from-drummer-s-dystonia-with-foot-and-arm-symptoms-after-stereotactic-ventro-oral-thalamotomy-a-case-report
#8
Takashi Asahi, Takaomi Taira, Kiyonobu Ikeda, Jiro Yamamoto, Shuji Sato
Ventro-oral (Vo) thalamotomy is effective in patients with focal task-specific dystonias (FTSDs), but only in those with upper-limb symptoms. We describe a patient with drummer's dystonia who completely recovered after Vo thalamotomy. A 37-year-old man who started playing drums at 14 began having difficulty performing fine movements with his right foot when drumming at 22. He experienced right hand cramps while drumming 3 months before visiting our hospital. He was diagnosed with FTSD. Left Vo thalamotomy was performed, which led to complete improvement of symptoms...
February 8, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29419852/-clinical-features-of-patients-with-becker-muscular-dystrophy-and-deletions-of-the-rod-domain-of-dystrophin-gene
#9
Yanyun Wang, Yuling Zhu, Juan Yang, Yaqin Li, Jiangwen Sun, Yixin Zhan, Cheng Zhang
OBJECTIVE To explore the clinical features of patients carrying deletions of the rod domain of the dystrophin gene. METHODS Clinical data of 12 Chinese patients with Becker muscular dystrophy (BMD) and such deletions was reviewed. RESULTS Most patients complained of muscle weakness of lower limbs. Two patients had muscle cramps, one had increased creatine kinase (CK) level, and one had dilated cardiomyopathy. CONCLUSION Compared with DMD, the clinical features of BMD are much more variable, particularly for those carrying deletions of the rod domain of the dystrophin gene...
February 10, 2018: Zhonghua Yi Xue Yi Chuan Xue za Zhi, Zhonghua Yixue Yichuanxue Zazhi, Chinese Journal of Medical Genetics
https://www.readbyqxmd.com/read/29413788/biomechanical-characteristics-of-lower-limb-gait-waveforms-associations-with-body-fat-in-children
#10
Ryan Mahaffey, Stewart C Morrison, Paul Bassett, Wendy I Drechsler, Mary C Cramp
BACKGROUND: Childhood obesity is associated with musculoskeletal dysfunction and altered lower limb biomechanics during gait. Few previous studies have explored relationships between childhood obesity measured by body fat and lower limb joint waveform kinematics and kinetics. RESEARCH QUESTION: What is the association between body fat and hip, knee and ankle joint angles and moments during gait and in 7 to 11 year-old boys? METHODS: Fifty-five boys participated in the study...
February 2, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29413216/acute-diverticulitis-management
#11
REVIEW
Deborah L Ellison
Diverticular disease accounts for approximately 300,000 hospitalizations per year in the United States, resulting in 1.5 million days of inpatient care. Diverticulitis is defined as an inflammation of the diverticulum, which can be asymptomatic or symptomatic. This disease is the third most common gastrointestinal illness that requires hospitalization and the leading indication for elective colon resection. Abdominal pain is the most common complaint in patients with acute diverticulitis. The pain can be described as cramping, constant, and persistent for several days...
March 2018: Critical Care Nursing Clinics of North America
https://www.readbyqxmd.com/read/29409786/cine-mri-during-spontaneous-cramps-in-women-with-menstrual-pain
#12
Kevin M Hellman, Caroline S Kuhn, Frank F Tu, Katlyn E Dillane, Nathan A Shlobin, Sangeeta Senapati, Xiaojie Zhou, Wei Li, Pottumarthi V Prasad
BACKGROUND: The lack of non-invasive methods to study dysmenorrhea has resulted in poor understanding of the mechanisms underlying pain, insufficient diagnostic tests, and limited treatment options. To address this knowledge gap, we have developed an MRI-based strategy for continuously monitoring the uterus in relation to participants' spontaneous pain perception. OBJECTIVE: The study objective was to evaluate whether MRI can detect real-time changes in myometrial activity during cramping episodes in women with dysmenorrhea, with a hand-held squeeze bulb for pain reporting...
January 31, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29399904/privacy-at-end-of-life-in-icu-a-review-of-the-literature
#13
Fiona Timmins, Stelios Parissopoulos, Sotirios Plakas, Margaret Theresa Naughton, Jan M A de Vries, Georgia Fouka
BACKGROUND: While the provision of ICU care is vital, the nature and effect of the potential lack of privacy during death and dying in ICUs has not been extensively explored. AIM: This paper aims to explore the issues surrounding privacy during death in ICU. DESIGN: A literature search using CINAHL and Pubmed revealed articles related to privacy, death and dying in ICU. METHOD: Key words used in the search were 'ICU', 'Privacy', 'Death' and 'Dying'...
February 5, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29399045/disease-modifying-and-symptomatic-treatment-of-amyotrophic-lateral-sclerosis
#14
REVIEW
Johannes Dorst, Albert C Ludolph, Annemarie Huebers
In this review, we summarize the most important recent developments in the treatment of amyotrophic lateral sclerosis (ALS). In terms of disease-modifying treatment options, several drugs such as dexpramipexole, pioglitazone, lithium, and many others have been tested in large multicenter trials, albeit with disappointing results. Therefore, riluzole remains the only directly disease-modifying drug. In addition, we discuss antisense oligonucleotides (ASOs) as a new and potentially causal treatment option. Progress in symptomatic treatments has been more important...
2018: Therapeutic Advances in Neurological Disorders
https://www.readbyqxmd.com/read/29396644/expression-and-localization-of-cramp-in-rat-tooth-germ-and-during-reparative-dentin-formation
#15
Kanji Horibe, Akihiro Hosoya, Toru Hiraga, Hiroaki Nakamura
OBJECTIVES: Cathelicidin-related antimicrobial peptide (CRAMP) is an antimicrobial peptide in mice and rats homologous to LL-37 in humans. In addition to its antibacterial activity, CRAMP has various physiological functions by binding to formyl peptide receptor 2 (FPR2). However, the role of these peptides in teeth is unknown. Therefore, we investigated the role of CRAMP and FPR2 in tooth development, reparative dentin formation, and defense response. MATERIAL AND METHODS: First, we examined the localization of CRAMP and FPR2 during tooth development by immunohistochemical analysis...
February 2, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29396243/-menopause-hypertension-and-vascular-disease
#16
J M Zilberman
Hypertension is the main cardiovascular risk factor affecting 25% of women. Hormone changes and hypertension after menopause may lead to higher target organ damage and cardiovascular disease such as increased arterial stiffness, coronary diseases, chronic heart failure and stroke. The physiopathological mechanisms involved in the development of hypertension and cardiovascular diseases in menopausal women are controversial. There are pharmacokinetic and pharmacodynamic differences in both sexes, the women have more coughing when using the converting-enzyme inhibitors, more cramps when using thiazide diuretics and more oedema in the inferior limbs when using calcium antagonists...
January 28, 2018: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/29395486/the-value-of-genetic-testing-in-polycystic-kidney-diseases-illustrated-by-a-family-with-pkd2-and-col4a1-mutations
#17
Emilie Cornec-Le Gall, Fouad T Chebib, Charles D Madsen, Sarah R Senum, Christina M Heyer, Brendan C Lanpher, Marc C Patterson, Robert C Albright, Alan S Yu, Vicente E Torres, Peter C Harris
The diagnosis of autosomal dominant polycystic kidney disease (ADPKD) relies on imaging criteria in the setting of a positive familial history. Molecular analysis, seldom used in clinical practice, identifies a causative mutation in >90% of cases in the genes PKD1, PKD2, or rarely GANAB. We report the clinical and genetic dissection of a 7-generation pedigree, resulting in the diagnosis of 2 different cystic disorders. Using targeted next-generation sequencing of 65 candidate genes in a patient with an ADPKD-like phenotype who lacked the familial PKD2 mutation, we identified a COL4A1 mutation (p...
January 27, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29393690/benefits-of-vaginal-misoprostol-prior-to-iud-insertion-in-women-with-previous-caesarean-delivery-a-randomised-controlled-trial
#18
Ahmed M Maged, Gamal Youssef, Ashraf Eldaly, Eman Omran, Mohamed El Naggar, Ahmed Abdel Hak, Amal Kotb, Asmaa I Ogila
OBJECTIVE: The aim of the study was to evaluate the value of vaginal misoprostol 6 h prior to intrauterine device (IUD) insertion in women with previous Caesarean delivery. METHODS: A double-blind randomised controlled trial was conducted in 120 women who were eligible for IUD insertion. Participants were randomly divided to receive either 600 μg vaginal misoprostol or placebo 6 h before IUD insertion. The primary outcome measure was the pain score during the procedure...
February 2, 2018: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/29389238/inflammatory-diseases-of-the-gut
#19
Michael Rohr, Chandrakala Aluganti Narasimhulu, Dhara Sharma, Mitsushita Doomra, Aladdin Riad, Saleh Naser, Sampath Parthasarathy
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are chronic inflammatory disorders of the gastrointestinal tract whose prevalence has been dramatically increasing over the past decade. New studies have shown that IBD is the second most common chronic inflammatory disease worldwide after rheumatoid arthritis, affecting millions of people mainly in industrialized countries. Symptoms of IBD include frequent bloody diarrhea, abdominal cramping, anorexia, abdominal distension, and emesis...
February 1, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29387653/operative-treatment-for-the-painful-posterior-thigh-after-hamstring-autograft-harvesting
#20
Mikko Laakso, Jussi Kosola, Pekka Niemi, Keijo Mäkelä, Juha Ranne, Sakari Orava, Lasse Lempainen
Background: Semitendinosus (ST) is widely used autograft in anterior cruciate ligament reconstructions (ACLR). Although tendon harvesting is a common procedure, some patients exhibit pain, cramping and dysfunctional at posterior thigh after the ACLR. The formation of the newly regenerated neotendon could be compromised by a new injury or too rapid rehabilitation. We present this clinical entity and the developed surgical technique and share our experience in treatment of these patients...
July 2017: Muscles, Ligaments and Tendons Journal
keyword
keyword
29176
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"