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https://www.readbyqxmd.com/read/28701947/protein-restricted-diets-for-ameliorating-motor-fluctuations-in-parkinson-s-disease
#1
REVIEW
Luxi Wang, Nian Xiong, Jinsha Huang, Shiyi Guo, Ling Liu, Chao Han, Guoxin Zhang, Haiyang Jiang, Kai Ma, Yun Xia, Xiaoyun Xu, Jie Li, Jing Y Liu, Tao Wang
Levodopa is considered to be the most effective symptomatic drug for Parkinson's disease (PD). As the disease progresses, however, the patients are likely to experience a reduced response to levodopa and develop motor fluctuations (i.e., end-of-dose wearing off and unpredictable "on-off"). Protein-rich diets and elevated plasma concentrations of large neutral amino acids have been proved to impair the therapeutic effect of levodopa by reducing its absorption and influx into the brain. On the other hand, the protein-restricted diets including low-protein diet (LPD), protein-redistribution diet (PRD) and PRD with use of low-protein products can all improve the efficacy of levodopa in patients with motor fluctuations...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28698515/post-disaster-food-and-nutrition-from-urban-agriculture-a-self-sufficiency-analysis-of-nerima-ward-tokyo
#2
Giles Bruno Sioen, Makiko Sekiyama, Toru Terada, Makoto Yokohari
Background: Post-earthquake studies from around the world have reported that survivors relying on emergency food for prolonged periods of time experienced several dietary related health problems. The present study aimed to quantify the potential nutrient production of urban agricultural vegetables and the resulting nutritional self-sufficiency throughout the year for mitigating post-disaster situations. Methods: We estimated the vegetable production of urban agriculture throughout the year. Two methods were developed to capture the production from professional and hobby farms: Method I utilized secondary governmental data on agricultural production from professional farms, and Method II was based on a supplementary spatial analysis to estimate the production from hobby farms...
July 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28687652/high-temporal-and-spatial-variability-of-atmospheric-methane-oxidation-in-alpine-glacier-forefield-soils
#3
Eleonora Chiri, Philipp A Nauer, Edda-Marie Rainer, Josef Zeyer, Martin H Schroth
Glacier-forefield soils can provide a substantial sink for atmospheric CH4, facilitated by aerobic methane-oxidizing bacteria (MOB). However, MOB activity, abundance, and community structure may be affected by soil age, location in different forefield landforms, and temporal fluctuations in soil-physical parameters. We assessed spatial and temporal variability of atmospheric CH4 oxidation in an Alpine glacier forefield during the snow-free season 2013. We quantified CH4 flux in soils of increasing age and in different landforms (sandhill, terrace, floodplain) using soil-gas-profile and static flux-chamber methods...
July 7, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28684334/just-a-thought-how-mind-wandering-is-represented-in-dynamic-brain-connectivity
#4
REVIEW
Aaron Kucyi
The neuroscience of mind-wandering has begun to flourish, with roles of brain regions and networks being defined for various components of spontaneous thought. However, often underappreciated is that most of brain activity does not represent immediately occurring thoughts. Instead, spontaneous, organized network activity largely reflects "intrinsic" functions that are unrelated to the current experience. There remains no consensus on how brain networks represent mind-wandering in parallel to functioning in other ongoing, predominantly unconscious processes...
July 3, 2017: NeuroImage
https://www.readbyqxmd.com/read/28679233/multifractal-temporally-weighted-detrended-cross-correlation-analysis-to-quantify-power-law-cross-correlation-and-its-application-to-stock-markets
#5
Yun-Lan Wei, Zu-Guo Yu, Hai-Long Zou, Vo Anh
A new method-multifractal temporally weighted detrended cross-correlation analysis (MF-TWXDFA)-is proposed to investigate multifractal cross-correlations in this paper. This new method is based on multifractal temporally weighted detrended fluctuation analysis and multifractal cross-correlation analysis (MFCCA). An innovation of the method is applying geographically weighted regression to estimate local trends in the nonstationary time series. We also take into consideration the sign of the fluctuations in computing the corresponding detrended cross-covariance function...
June 2017: Chaos
https://www.readbyqxmd.com/read/28679099/body-weight-fluctuations-and-outcomes-in-coronary-disease
#6
LETTER
Tim Christen, Renée de Mutsert
No abstract text is available yet for this article.
July 6, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28679098/body-weight-fluctuations-and-outcomes-in-coronary-disease
#7
LETTER
Sripal Bangalore, Franz H Messerli, David D Waters
New England Journal of Medicine, Volume 377, Issue 1, Page 94-96, July 2017.
July 6, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28679015/association-between-weight-change-health-outcomes-and-mortality-in-older-residents-in-long-term-care
#8
Wei Zhou, Andrzej Kozikowski, Renee Pekmezaris, James Lolis, Barbara Tommasulo, Joanna Fishbein, Gisele Wolf-Klein
OBJECTIVES: Despite the numerous health risks associated with being overweight, the effect of weight loss on health and longevity remains controversial, particularly in older adults. We explored the association among weight changes, health outcomes, and mortality in older residents of a skilled nursing facility. METHODS: A 6-year retrospective chart review of residents of a long-term care facility was conducted, collecting monthly weights in addition to the clinical and demographic data of all residents for at least 1 year...
July 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28676842/subthalamic-nucleus-deep-brain-stimulation-in-early-stage-parkinson-s-disease-is-not-associated-with-increased-body-mass-index
#9
Sarah H Millan, Mallory L Hacker, Maxim Turchan, Anna L Molinari, Amanda D Currie, David Charles
Previous studies suggest that deep brain stimulation of the subthalamic nucleus (STN-DBS) for Parkinson's disease (PD) leads to weight gain. This study analyzes changes in body mass index (BMI) in 29 subjects from a prospective, single-blind trial of DBS in early stage PD (age 50-75, Hoehn & Yahr stage II off medication, treated with antiparkinsonian medications for ≥6 months but <4 years, and without a history of motor fluctuations, dyskinesias, or dementia). Subjects were randomized to DBS plus optimal drug therapy (DBS+ODT; n = 15) or ODT (n = 14) and followed for 24 months...
2017: Parkinson's Disease
https://www.readbyqxmd.com/read/28676555/composition-of-two-week-change-in-body-weight-under-unrestricted-free-living-conditions
#10
Surabhi Bhutani, Eva Kahn, Esra Tasali, Dale A Schoeller
The composition of weight change has a large impact on energy balance calculations. Composition of long-term weight change interventions is well-documented, but information on short-term weight change under unrestricted free-living conditions is limited. The composition and energy density of the changes in body weight during 2-week free-living conditions were analyzed in adults from two cohorts: cohort 1 (n = 24) included participants from the reproducibility subset of the Observing Protein and Energy Nutrition study; cohort 2 (n = 22) included participants who were studied under free-living conditions in an ongoing study in the Chicago area...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28672237/long-term-variation-in-concentrations-and-mass-loads-in-a-semi-arid-watershed-influenced-by-historic-mercury-mining-and-urban-pollutant-sources
#11
Lester J McKee, Autumn Bonnema, Nicole David, Jay A Davis, Amy Franz, Richard Grace, Ben K Greenfield, Alicia N Gilbreath, Cristina Grosso, Wesley A Heim, Jennifer A Hunt, Jon E Leatherbarrow, Sarah Lowe, Sarah A Pearce, John R M Ross, Donald Yee
Urban watersheds are significantly anthropogenically-altered landscapes. Most previous studies cover relatively short periods, without addressing concentrations, loads, and yields in relation to annual climate fluctuations, and datasets on Ag, Se, PBDEs, and PCDD/Fs are rare. Intensive storm-focused sampling and continuous turbidity monitoring were employed to quantify pollution at two locations in the Guadalupe River (California, USA). At a downstream location, we determined loads of suspended sediment (SS) for 14yrs...
June 30, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28660517/dynamic-water-quality-evaluation-based-on-fuzzy-matter-element-model-and-functional-data-analysis-a-case-study-in-poyang-lake
#12
Bing Li, Guishan Yang, Rongrong Wan, Georg Hörmann
Comprehensively evaluating water quality with a single method alone is challenging because water quality evaluation involves complex, uncertain, and fuzzy processes. Moreover, water quality evaluation is limited by finite water quality monitoring that can only represent water quality conditions at certain time points. Thus, the present study proposed a dynamic fuzzy matter-element model (D-FME) to comprehensively and continuously evaluate water quality status. D-FME was first constructed by introducing functional data analysis (FDA) theory into a fuzzy matter-element model and then validated using monthly water quality data for the Poyang Lake outlet (Hukou) from 2011 to 2012...
June 28, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28656943/evaluation-of-certain-pharmaceutical-quality-attributes-of-lisinopril-split-tablets
#13
Khairi M S Fahelelbom, Moawia M M Al-Tabakha, Nermin A M Eissa, Jeevani Javadi
Tablet splitting is an accepted practice for the administration of drugs for a variety of reasons, including dose adjustment, ease of swallowing and cost savings. The purpose of this study was to evaluate the physical properties of lisinopril tablets as a result of splitting the tablets either by hand or with a splitting device. The impact of the splitting technique of lisinopril (Zestril(®) tablets, 20 mg) on certain physical parameters such as weight variation, friability, disintegration, dissolution and drug content were studied...
October 11, 2016: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/28656097/a-comparative-study-of-the-effect-of-nasal-intermittent-positive-pressure-ventilation-and-nasal-continuous-positive-airway-pressure-on-the-regional-brain-tissue-oximetry-in-premature-newborns-weighing-1500-g
#14
Alireza Sadeghnia, Marzieh Zamani Foroshani, Zohreh Badiei
BACKGROUND: Near-infrared spectroscopy (NIRS) provides the capability of monitoring oxygenation levels in cerebral microscopic vessels, enabling the operator to observe the spontaneous changes in the levels of hemoglobin concentration in tissue and interpret the resulting fluctuations. The current study tried to investigate whether brain's autoregulatory mechanisms in premature newborns have the potential to prevent the adverse effects caused by asynchronous changes of pressure in the rib cage...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28646751/an-attentional-drift-diffusion-model-over-binary-attribute-choice
#15
Geoffrey Fisher
In order to make good decisions, individuals need to identify and properly integrate information about various attributes associated with a choice. Since choices are often complex and made rapidly, they are typically affected by contextual variables that are thought to influence how much attention is paid to different attributes. I propose a modification of the attentional drift-diffusion model, the binary-attribute attentional drift diffusion model (baDDM), which describes the choice process over simple binary-attribute choices and how it is affected by fluctuations in visual attention...
June 21, 2017: Cognition
https://www.readbyqxmd.com/read/28641772/susac-syndrome-a-differential-diagnosis-of-white-matter-lesions
#16
Mariano Marrodan, Jorge Correale, Lucas Alessandro, Mariela Amaya, Maria Eugenia Fracaro, Alejandro Alfredo Köhler, Marcela Fiol
INTRODUCTION: Susac Syndrome is an autoimmune endotheliopathy affecting capillaries and precapillary arterioles of the brain, inner ear and retina. The classic symptom triad includes visual disturbances, hypoacusia, and encephalopathy, but is rarely fully manifest at onset. The syndrome typically follows an active fluctuating monophasic course. Typical imaging findings on brain magnetic resonance show central fiber microischemias/microinfarctions of the corpus callosum known as "snow balls", as well as lineal infarcts and upper callosal fiber involvement...
July 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28639624/nearest-neighbour-resonating-valence-bonds-in-ybmggao4
#17
Yuesheng Li, Devashibhai Adroja, David Voneshen, Robert I Bewley, Qingming Zhang, Alexander A Tsirlin, Philipp Gegenwart
Since its proposal by Anderson, resonating valence bonds (RVB) formed by a superposition of fluctuating singlet pairs have been a paradigmatic concept in understanding quantum spin liquids. Here, we show that excitations related to singlet breaking on nearest-neighbour bonds describe the high-energy part of the excitation spectrum in YbMgGaO4, the effective spin-1/2 frustrated antiferromagnet on the triangular lattice, as originally considered by Anderson. By a thorough single-crystal inelastic neutron scattering study, we demonstrate that nearest-neighbour RVB excitations account for the bulk of the spectral weight above 0...
June 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/28634292/monte-carlo-sampling-for-stochastic-weight-functions
#18
Daan Frenkel, K Julian Schrenk, Stefano Martiniani
Conventional Monte Carlo simulations are stochastic in the sense that the acceptance of a trial move is decided by comparing a computed acceptance probability with a random number, uniformly distributed between 0 and 1. Here, we consider the case that the weight determining the acceptance probability itself is fluctuating. This situation is common in many numerical studies. We show that it is possible to construct a rigorous Monte Carlo algorithm that visits points in state space with a probability proportional to their average weight...
June 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28629860/hydrogen-deuterium-exchange-kinetics-in-%C3%AE-lactoglobulin-epicatechin-complexes-studied-by-ftir-spectroscopy
#19
Francesca Caporaletti, Marina Carbonaro, Paola Maselli, Alessandro Nucara
Hydrogen-Deuterium exchange kinetics of β-lactoglobulin and β-lactoglobulin (-)-epicatechin solutions has been investigated through the analysis of the amide I absorption band at 1650cm(-1) in the FTIR spectrum. H-D substitution in NH amides and residues of the protein results in a slight red-shift and in intensity changes of the amide I components: either these effects have been inspected in the framework of the Principal Components Analysis methods. The present analysis allowed to unveil three H-D kinetics at the timescale of the oligomeric fluctuations of the protein...
June 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28628636/weight-change-across-the-start-of-three-consecutive-pregnancies-and-the-risk-of-maternal-morbidity-and-sga-birth-at-the-second-and-third-pregnancy
#20
Jacqueline M Wallace, Sohinee Bhattacharya, Graham W Horgan
BACKGROUND: Weight-change across parities and/or current BMI may influence maternal and fetal morbidity and requires to be differentiated to better inform weight-management guidance. METHODS: Direction, pattern and magnitude of weight-change across three consecutive parities and thereby two inter-pregnancy periods was described in 5079 women. The association between inter-pregnancy weight-change versus current BMI and adverse maternal events, SGA-birth and preterm delivery at second and third pregnancy were investigated by logistic regression...
2017: PloS One
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