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https://www.readbyqxmd.com/read/29055269/decision-making-measured-by-the-iowa-gambling-task-in-alcohol-use-disorder-and-gambling-disorder-a-systematic-review-and-meta-analysis
#1
REVIEW
Ildikó Kovács, Mara J Richman, Zoltán Janka, Aniko Maraz, Bálint Andó
BACKGROUND AND AIMS: Gambling disorder (GD) and alcohol use disorder (AD) have similar features, such as elevated impulsivity and decision-making deficits, which are directly linked to relapse and poor therapeutic outcomes. Our aim was to assess decision-making characteristics in GD and AD patients compared to healthy controls (HC) based on one of the most frequently used measures of decision-making: the Iowa Gambling Task (IGT). METHODS: In our systematic literature search of three databases, we identified 1198 empirical articles that mentioned decision-making deficits with the use of the IGT in patients diagnosed with either AD or GD...
October 12, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29055267/nature-differences-of-fulvic-acid-fractions-induced-by-extracted-sequence-as-explanatory-factors-for-binding-characteristics-of-cu-2
#2
Zhenrui Zhang, Changwei Lü, Jiang He, Manshu Gao, Boyi Zhao, Bin Zhou, Jing Guo, Haijun Zhou, Xiaoting Liu, Zhuoming Li, Wenjing Shi, Yongjie Jiao, Wenxi Zhao, Yu Zhang
The isolation of fulvic acid (FA) fractions with relatively homogeneity is a key to reveal the binding mechanisms between FA and heavy metals. In this work, nine FA fractions were obtained using sequential alkali extraction procedure and nature differences of the extracted FA fractions were considered as explanatory factors for binding characteristics of Cu(2+). The results indicate that the contents of carboxyl and phenolic groups decrease with increasing extractions along with an opposite trend for the content of nitrogen-containing groups...
October 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/29055250/clinical-characteristics-of-patients-with-diagnostic-uncertainty-of-major-depressive-disorder
#3
Taichi Mogi, Hiroyuki Toda, Aihide Yoshino
BACKGROUND: Physicians do not always confidently diagnose psychiatric disorders. The present study was conducted to identify the clinical characteristics of patients in whom a definitive diagnosis of major depressive disorder (MDD) could not be established. METHODS: The participants were 199 consecutive outpatients with MDD, who were comprehensively diagnosed using the Mini International Neuropsychiatric Interview (MINI). The physician in charge of each patient quantified his/her sense of self-confidence in diagnosing the patient with MDD using the self-rating questionnaire in which the score ranged from 1 (not at all confident) to 5 (definitely MDD)...
October 16, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29055244/a-pilot-study-comparing-mechanical-properties-of-tissue-engineered-cartilages-and-various-endogenous-cartilages
#4
Andrew K Pappa, Sajjad Soleimani, Montserrat Caballero, Alexandra E Halevi, John A van Aalst
BACKGROUND: Mechanical properties of tissue-engineered cartilage and a variety of endogenous cartilage were measured. The main goal was to evaluate if the tissue-engineered cartilage have similar mechanical characteristics to be replaced with rib cartilage in microtia reconstruction. Such study lays the foundation for future human clinical trials for microtia reconstruction. METHOD: Atomic force microscopy and compression testing were used to measure the viscoelasticity of tissue-engineered cartilage (stem cell seeded on Poly lactic co-glycolytic acid nanofibers and Pellet) and endogenous cartilage: conchal bowl, microtic ears, preauricular remnants, and rib...
October 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/29055230/development-and-evaluation-of-novel-biodegradable-chitosan-based-metformin-intrapocket-dental-film-for-the-management-of-periodontitis-and-alveolar-bone-loss-in-a-rat-model
#5
Deepak Kumar Khajuria, Omprakash Nandikamba Patil, David Karasik, Rema Razdan
OBJECTIVE: The aim of this study was to develop a chitosan-metformin based intrapocket dental film (CMIDF) for applications in the treatment of periodontitis and alveolar bone loss in an rat model of periodontitis. DESIGN: CMIDF inserts were fabricated by the solvent casting technique. The fabricated inserts were evaluated for physical characteristics such as folding endurance, surface pH, mucoadhesive strength, metformin content uniformity, and release. X-ray diffraction analysis indicates no crystallinity of metformin in presence of chitosan which confirmed successful entrapment of metformin into the CMIDF...
October 16, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29055208/measuring-alcohol-use-across-the-transition-to-adulthood-racial-ethnic-sexual-identity-and-educational-differences
#6
Jessica N Fish, Amanda M Pollitt, John E Schulenberg, Stephen T Russell
BACKGROUND: Patterns of alcohol use change from adolescence to adulthood and may differ based on race/ethnicity, sexual identity, and education. If alcohol use measures do not operate consistently across groups and developmental periods, parameter estimates and conclusions may be biased. OBJECTIVES: To test the measurement invariance of a multi-item alcohol use measure across groups defined by race/ethnicity, sexual identity, and college education during the transition to adulthood...
October 12, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/29055206/simultaneous-stabilization-solidification-of-mn-2-and-nh4-n-from-electrolytic-manganese-residue-using-mgo-and-different-phosphate-resource
#7
Jiancheng Shu, Haiping Wu, Renlong Liu, Zuohua Liu, Bing Li, Mengjun Chen, Changyuan Tao
This study examined simultaneous stabilization and solidification (S/S) of Mn(2+) and NH4(+)-N from electrolytic manganese residue (EMR) using MgO and different phosphate resource. The characteristics of EMR NH4(+)-N and Mn(2+) S/S behavior, S/S mechanisms, leaching test and economic analysis, were investigated. The results show that the S/S efficiency of Mn(2+) and NH4(+)-N could reach 91.58% and 99.98%, respectively, and the pH value is 8.75 when the molar ratio of Mg:P is 3:1 and the dose of PM (MgO and Na3PO4·12H2O) is 8wt%...
October 18, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29055186/designed-inhibitors-with-hetero-linkers-for-gastric-proton-pump-h-k-atpase-steered-molecular-dynamics-and-metadynamics-studies
#8
Kalyanashis Jana, Tusar Bandyopadhyay, Bishwajit Ganguly
Acid suppressant SCH28080 and its derivatives reversibly reduce acid secretion activity of the H(+),K(+)-ATPase in a K(+) competitive manner. The results on homologation of the SCH28080 by varying the linker chain length suggested the improvement in efficacy. However, the pharmacokinetic studies reveal that the hydrophobic nature of the CH2 linker units may not help it to function as a better acid suppressant. We have exploited the role of linker unit to enhance the efficacy of such reversible acid suppressant drug molecules using hetero linker, i...
October 12, 2017: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/29055156/type-2-diabetes-remission-2-years-post-roux-en-y-gastric-bypass-and-sleeve-gastrectomy-the-role-of-the-weight-loss-and-comparison-of-diarem-and-diabetter-scores
#9
A Pucci, U Tymoszuk, W H Cheung, J M Makaronidis, S Scholes, G Tharakan, M Elkalaawy, M Guimaraes, M Nora, M Hashemi, A Jenkinson, M Adamo, M Monteiro, N Finer, R L Batterham
AIMS: The comparative efficacy of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy on Type 2 diabetes remission and the role of weight loss are unclear. The DiaRem Type 2 diabetes remission prediction score uses HbA1c , age and Type 2 diabetes medications but not Type 2 diabetes duration. The aim of this study was to compare the predictive value of the DiaRem score with the DiaBetter score that includes Type 2 diabetes duration, upon combined (complete plus partial) 2-year post-surgery Type 2 diabetes remission in people following RYGB and sleeve gastrectomy, and to investigate the relationship between weight loss and Type 2 diabetes remission...
October 21, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29055153/defining-the-actinic-keratosis-field-a-literature-review-and-discussion
#10
REVIEW
I Figueras Nart, R Cerio, T Dirschka, B Dréno, J T Lear, G Pellacani, K Peris, A Ruiz de Casas
BACKGROUND: Despite the chronic and increasingly prevalent nature of actinic keratosis (AK) and existing evidence supporting assessment of the entire cancerization field during clinical management, a standardized definition of the AK field to aid in the understanding and characterization of the disease is lacking. OBJECTIVES: The objective of this review is to present and appraise the available evidence describing the AK cancerization field, with the aim of determining a precise definition of the AK field in terms of its molecular (including genetic and immunological), histological, and clinical characteristics...
October 21, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29055147/cognitive-function-among-long-term-survivors-of-heart-transplantation
#11
Britta S Bürker, Einar Gude, Lars Gullestad, Ingelin Grov, Anne Relbo Authen, Arne K Andreassen, Odd E Havik, Mary Amanda Dew, Arnt E Fiane, Ira R Haraldsen, Ulrik F Malt, Stein Andersson
BACKGROUND: Cognitive impairment is documented early after heart transplantation (HTx), but we lack data on cognitive function beyond the fourth year posttransplant. Against the background of good long-term survival, this knowledge is necessary to improve clinical care throughout the entire posttransplant period. METHODS: We assessed cognitive function with a neuropsychological test battery in a sample of HTx recipients ≥16 years posttransplant. To improve clinical utility, we also applied adapted consensus criteria for Mild Cognitive Impairment (MCI)...
October 21, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/29055140/morphological-analysis-of-the-male-reproductive-accessory-glands-of-the-bat-artibeus-lituratus-phyllostomidae-chiroptera
#12
Renata T S Santos, Laís R M Pires, Edna S S Albernaz, Cleber S Andrade, Cornélio S Santiago, Eliana Morielle-Versute, Sebastião R Taboga, Mateus R Beguelini
Bats are distributed worldwide from tropical to temperate regions. Despite their wide geographical radiation and advances in studies using evolutionary approaches, aspects related to the reproduction of these animals remain poorly explored, especially those related to the male reproductive accessory glands (RAGs). Thus, the aim of this study was to analyze the morphophysiology of the male RAGs in the bat Artibeus lituratus. The RAGs in A. lituratus are composed of a compact intra-abdominal glandular complex, consisting of the prostate with two prostatic regions (ventral and dorsal), plus Littre glands and a pair of extra-abdominal bulbourethral glands...
October 21, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29055138/effects-of-a-bone-graft-substitute-consisting-of-porous-gradient-ha-zro2-and-gelatin-chitosan-slow-release-hydrogel-containing-bmp-2-and-bmscs-on-lumbar-vertebral-defect-repair-in-rhesus-monkey
#13
Rong-Xue Shao, Ren-Fu Quan, Tuo Wang, Wei-Bin Du, Gao-Yong Jia, Dong Wang, Long-Bao Lv, Cai-Yin Xu, Xi-Cheng Wei, Jin-Fu Wang, Di-Sheng Yang
Dense biomaterial plays an important role in bone replacement. However, it fails to induce bone-cell migration into graft material. In the present study, a novel bone-graft substitute (BGS) consisting of porous gradient HA/ZrO2 composite (PGHC) and gelatin/chitosan slow-release hydrogel containing BMP-2 and BMSCs was designed and prepared to repair lumbar vertebral defects. The morphological characteristics of the BGS evaluated by scanning electron microscope showed that it had a three-dimensional network structure with uniformly distributed chitosan microspheres on the surfaces of the graft material and the interior of the pores...
October 21, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29055136/the-rhinoceros-among-serpents-comparative-anatomy-and-experimental-biophysics-of-calabar-burrowing-python-calabaria-reinhardtii-skin
#14
Dawei Han, Bruce A Young
The Calabar burrowing python (Calabaria reinhardtii) has a unique combination of marked thickness of the integumentary layers, a highly organized lamellate arrangement of the dermal collagen bundles, and a reduction in the size of the interscale hinge region of the integument. Biomechanical testing demonstrates that the skin of C. reinhardtii is more resistant to penetration than the skin of other snakes. The laminar arrangement of the collagen bundles provides for penetrative resistance, even while maintaining the flexibility characteristic of snake skin...
October 21, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29055128/a-generalized-outflow-boundary-condition-impedance-model-for-non-invasive-prediction-of-ischemia-in-diseased-coronary-arteries
#15
Iyad A Fayssal, Fadl Moukalled, Samir Alam, Hussain Isma'eel
This paper reports on a new boundary condition formulation to model the total coronary myocardial flow and impedance characteristics of the myocardial vascular bed for any specific patient when considered for non-invasive diagnosis of fractional flow reserve (FFR). The developed boundary condition model inherits an implicit representation of the downstream truncated vascular bed and is based on integrating patient-specific physiologic parameters that can be non-invasively extracted for each patient to account for blood flow demand to the myocardium at rest and hyperemic conditions...
October 21, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29055127/shoe-floor-interactions-in-human-walking-with-slips-modeling-and-experiments
#16
Mitja Trkov, Jingang Yi, Tao Liu, Kang Li
Shoe-floor interactions play a crucial role in determining the possibility of potential slip and fall during human walking. Biomechanical and tribological parameters influence the friction characteristics between the shoe sole and the floor and the existing work mainly focus on experimental studies. In this paper, we present modeling, analysis, and experiments to understand slip and force distributions between the shoe sole and floor surface during human walking. We present results for both soft and hard sole material...
October 21, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29055077/genetic-association-and-phenotypic-correlation-of-tlr4-but-not-nod2-variants-with-tunisian-inflammatory-bowel-disease
#17
Sawsan Feki, Dorra Bouzid, Olfa Abida, Lassaad Chtourou, Nesrine Elloumi, Amina Toumi, Hend Hachicha, Ali Amouri, Nabil Tahri, Hatem Masmoudi
OBJECTIVE: The common association of NOD2/CARD15 and TLR4 genes variants with inflammatory bowel disease (IBD) have not been universally replicated. We aimed to study the polymorphism of these two genes in Tunisian patients with IBD. METHODS: Polymorphism of NOD2 (R702W, G908R and 1007fs) and TLR4 (Asp299Gly and Thr399Ile) genes were analyzed in 106 IBD patients (68 ulcerative colitis (UC), 38 Crohn's disease (CD)) and 160 healthy controls using PCR-RFLP. A genotype-phenotype correlation was performed...
October 20, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/29055053/expression-patterns-of-ion-channels-and-structural-proteins-in-a-multimodal-cell-type-of-the-avian-optic-tectum
#18
Katharina Lischka, Simone Ladel, Harald Luksch, Stefan Weigel
The midbrain is an important subcortical area involved in distinct functions such as multimodal integration, movement initiation, bottom-up and top-down attention. Our group is particularly interested in cellular computation of multisensory integration. We focus on the visual part of the avian midbrain, the optic tectum (TeO, counterpart to mammalian superior colliculus). This area has a layered structure with the great advantage of distinct in- and output regions. In chicken, the TeO is organized in 15 layers where visual input targets the superficial layers while auditory input terminates in deeper layers...
October 21, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29055046/an-assessment-of-depression-psychosocial-factors-and-resilience-among-women-seeking-prenatal-care-at-an-urban-community-health-center
#19
Katherine M Johnson, Frances M Paley, Anna M Modest, Michele R Hacker, Sabine Shaughnessy, Hope A Ricciotti, Jennifer Scott
OBJECTIVE: To describe the relationship between resilience and mental health and psychosocial characteristics in the prenatal period. METHODS: A prospective cohort pilot study was conducted among English-speaking women aged 18 years or older with singleton pregnancies of at least 20 weeks' duration who received prenatal care at an urban community health center in the USA between March and October 2014. Surveys were administered and a retrospective chart review was conducted...
October 20, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29055045/diagnostic-relevance-of-ige-sensitization-profiles-to-eight-recombinant-phleum-pratense-molecules
#20
Francesca Cipriani, Carla Mastrorilli, Salvatore Tripodi, Giampaolo Ricci, Serena Perna, Valentina Panetta, Riccardo Asero, Arianna Dondi, Annamaria Bianchi, Nunzia Maiello, Michele Miraglia Del Giudice, Tullio Frediani, Francesco Macrì, Sandra Lucarelli, Iride Dello Iacono, Maria Francesca Patria, Elena Varin, Diego Peroni, Loredana Chini, Viviana Moschese, Roberto Bernardini, Giuseppe Pingitore, Umberto Pelosi, Mariangela Tosca, Francesco Paravati, Ifigenia Sfika, Andrea Di Rienzo Businco, Calotta Povesi Dascola, Pasquale Comberiati, Simone Frediani, Caterina Lambiase, Maria Carmen Verga, Diego Faggian, Mario Plebani, Mauro Calvani, Carlo Caffarelli, Paolo Maria Matricardi
BACKGROUND: Grass pollen-related seasonal allergic rhinoconjunctivitis (SARg) is clinically heterogeneous in severity, comorbidities and response to treatment. The component-resolved diagnostics disclosed also a high heterogeneity at molecular level. Our study aimed at analyzing the characteristics of the IgE sensitization to Phleum pratense molecules and investigating the diagnostic relevance of such molecules in childhood. METHODS: We examined 1120 children (age 4-18y) with SARg...
October 20, 2017: Allergy
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