Read by QxMD icon Read


S M Shugurov, A I Panin, S I Lopatin
RATIONALE: CeO2 -WO3 and CeO2 -MoO3 catalysts have shown excellent performance in the selective reduction of NOx by ammonia (NH3 -selective catalytic reduction) over a wide temperature range. Strong interaction between CeO2 and WO3 or MoO3 might be the dominant reason for the high activity of these mixed oxides. Studies of ceria-containing gaseous salts involve considerable experimental difficulties, since the transition of such salts to vapor requires high temperatures. To predict the possibility of the existence of gaseous associates formed by cerium and molybdenum (tungsten) oxides it is important to know their thermodynamic characteristics...
June 21, 2018: Rapid Communications in Mass Spectrometry: RCM
Jiayin Diao, Can Xu, Huiting Zheng, Siyi He, Shumei Wang
Viticis Fructus is a traditional Chinese herbal drug processed by various methods to achieve different clinical purposes. Thermal treatment potentially alters chemical composition, which may impact on effectiveness and toxicity. In order to interpret the constituent discrepancies of raw versus processed (stir-fried) Viticis Fructus, a multivariate detection method (NIR, HPLC, and UPLC-MS) based on metabonomics and chemometrics was developed. Firstly, synergy interval partial least squares and partial least squares-discriminant analysis were employed to screen the distinctive wavebands (4319 - 5459 cm-1 ) based on preprocessed near-infrared spectra...
June 21, 2018: Planta Medica
Dmitrii Pankin, Ilya Kolesnikov, Anna Vasileva, Anna Pilip, Vladislav Zigel, Alina Manshina
Raman spectra of the different ecotoxicants such as perfluorooctane sulfonate acid, organotin compounds of different families tributyl-, and triphenyl-, as well as chemically close compounds belonging to the same family - such as mono-, di-, and tributyl organotin compounds were analyzed. The comprehensive Raman spectra analysis allowed suggesting the identification scheme for clear recognition of the toxins family and the following intra-group specification. Possibility of unambiguous toxins detection and identification was demonstrated also for complex mixtures of various toxins on a base of control of characteristic peak groups, which can be considered as Raman fingerprints of the listed environmentally hazardous substances...
June 13, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Pamela Anelli, Steve W Peterson, Miriam Haidukowski, Antonio F Logrieco, Antonio Moretti, Filomena Epifani, Antonia Susca
Several species of the genus Penicillium were isolated during a survey of the mycobiota of Apulian cave cheeses ripened in a cave in Gravina di Puglia, Italy. A novel species, Penicillium gravinicasei, is described in Penicillium section Cinnamopurpurea. Its taxonomic novelty was determined using a polyphasic approach, combining phenotypic, molecular (β-tubulin, calmodulin, ITS and DNA dependent RNA polymerase) DNA sequences and mycotoxin production data. Phylogenetic analyses of the RPB2 data showed that isolates of the novel species form a clade most closely related to Penicillium cinnamopurpureum and P...
June 8, 2018: International Journal of Food Microbiology
Jisong Yang, Chao Zhan, Yunzhao Li, Di Zhou, Yang Yu, Junbao Yu
Increasing salinity has important impacts on biogeochemical processes in estuary wetlands, with the potential to influence the soil respiration, dissolved organic carbon (DOC) and microbial population. However, it is unclear how soil respiration is related to changes in the DOC and microbial community composition with increasing salinity. In this study, soil cores were sampled from a brackish wetland in the Liaohe River estuary and treated by salinity solutions at four levels (fresh water, 3‰, 5‰, and 10‰)...
June 18, 2018: Science of the Total Environment
Candice Y Lumibao, Stephen Formel, Vijaikrishnah Elango, John H Pardue, Michael Blum, Sunshine A Van Bael
The plant microbiome, composed of diverse interacting microorganisms, is thought to undergird host integrity and well-being. Though it is well understood that environmental perturbations like oil pollution can alter the diversity and composition of microbiomes, remarkably little is known about how disturbance alters plant-fungal associations. Using Next-Generation sequencing of the 18S rDNA internal transcribed spacer (ITS1) region, we examined outcomes of enduring oil exposure on aboveground leaf and belowground endophytic root and rhizosphere fungal communities of Spartina alterniflora, a highly valued ecosystem engineer in southeastern Louisiana marshes affected by the 2010 Deepwater Horizon accident...
June 18, 2018: Science of the Total Environment
Yang Song, Ling-Lei Zhang, Jia Li, Xiao-Jia He, Min Chen, Yun Deng
Water contamination by nickel (Ni) has become an increasing concern in recent decades. Hydrilla verticillata (L.f.) Royle has been recognized as a promising accumulator of several potentially toxic elements (PTEs) in phytoremediation, but its Ni-accumulation characteristics and its mechanisms of tolerance to Ni remain largely unknown. This research investigated the biochemical responses of leaves and stems of H. verticillata to various concentrations of Ni (5, 10, 15, 20, and 40 μM) over periods of 7, 14, or 21 days...
June 18, 2018: Ecotoxicology and Environmental Safety
Krutika Joshi, Lily Shen, Feng Cao, Susan Dong, Zhengping Jia, Miguel A Cortez, O Carter Snead
OBJECTIVE: Infantile spasms (IS) is a catastrophic childhood seizure disorder that is characterized by extensor and/or flexor spasms, cognitive deterioration and a characteristic EEG abnormality. The latter consists of a pattern of a spike-wave followed by an electrodecremental response (EDR), which is a flattening of the EEG waveform amplitude. The mechanism/circuitry that underpins IS is unknown. Children with Down Syndrome (DS) are particularly vulnerable to IS. The standard mouse model of DS is the Ts65Dn mutant mouse (Ts)...
June 12, 2018: Epilepsy Research
Kirsten Sundby Hall, Øyvind S Bruland, Bodil Bjerkehagen, Olga Zaikova, Jacob Engellau, Oskar Hagberg, Lina Hansson, Hans Hagberg, Marie Ahlström, Heidi Knobel, Karin Papworth, Maja Zemmler, Dorota Goplen, Henrik C F Bauer, Mikael Eriksson
PURPOSE: To investigate the outcome following adjuvant doxorubicin and ifosfamide in a prospective non-randomised study based on a soft tissue sarcoma (STS) patient subgroup defined by specific morphological characteristics previously shown to be at a high-risk of metastatic relapse. The expected 5-year cumulative incidence of metastases in patients with this risk profile has previously been reported to be about 50% without adjuvant chemotherapy. METHODS: High-risk STS was defined as high-grade morphology (according to the Fédération Nationale des Centres de Lutte Contre le Cancer [FNCLCC] grade II-III) and either vascular invasion or at least two of the following criteria: tumour size ≥8...
June 18, 2018: European Journal of Cancer
Eleonora Iob, Clemens Kirschbaum, Andrew Steptoe
INTRODUCTION: While positive social support is associated with lower prevalence of disease and better treatment outcomes, negative social relationships can instead have unfavourable consequences for several physical and mental health conditions. However, the specific mechanisms by which this nexus might operate remain poorly understood. Hypothalamic-pituitary-adrenal (HPA) axis hyperactivity owing to psychosocial stress has been proposed as a potential pathway underlying the link between social support and health...
June 12, 2018: Psychoneuroendocrinology
Suman B Iyer, Anshuman Dube, N M Dube, Pratik Roy, R R N Sailaja
The development of a suitable polymeric bioactive composite with hydroxyapatite as a filler is one of the very actively pursued areas in bioapplications. This report concerns development of such a novel polymeric biocomposite viz. poly (aryl ether) ketone-poly (dimethylsiloxane) with a small percentage of nano carbon fibres and varying percentages of nanohydroxyapatite particulates as fillers. The earlier characterization of this material involving mechanical, thermal and bio-compatibility studies showed optimum improved behaviour at about 7% nanohydroxyapatite loading as reported elsewhere...
June 6, 2018: Journal of the Mechanical Behavior of Biomedical Materials
Eloise Crush, Louise Arseneault, Terrie E Moffitt, Andrea Danese, Avshalom Caspi, Sara R Jaffee, Timothy Matthews, Helen L Fisher
Experiencing multiple types of victimization (poly-victimization) during adolescence is associated with the onset of psychotic experiences (such as hearing voices, having visions, or being extremely paranoid). However, many poly-victimized adolescents will not develop such subclinical phenomena and the factors that protect them are unknown. This study investigated whether individual, family, or community-level characteristics were associated with an absence of psychotic experiences amongst poly-victimized adolescents...
June 12, 2018: Journal of Psychiatric Research
Kate Hoffman, Stephanie C Hammel, Allison L Phillips, Amelia M Lorenzo, Albert Chen, Antonia M Calafat, Xiaoyun Ye, Thomas F Webster, Heather M Stapleton
Semi-volatile organic compounds (SVOCs) are used extensively in consumer and personal care products; electronics; furniture; and building materials and are detected in most indoor environments. As a result, human exposure to mixtures of SVOCs is wide-spread. However, very few studies have measured biomarkers of exposure to multiple SVOC classes, and exposure determinants have not been thoroughly explored, particularly for young children. In this study, we investigated biomarkers of exposure to SVOCs among children (age 3-6 years), who may experience higher exposures and be more susceptible to adverse health outcomes than other age groups...
June 18, 2018: Environment International
Jiancheng Yang, Xiaofeng Meng, Dandan Dong, Yanru Xue, Xin Chen, Shenghang Wang, Ying Shen, Gejing Zhang, Peng Shang
During deep-space exploration missions, astronauts will be exposed to abnormal space environments including microgravity and hypomagnetic field (HyMF) that is 10,000 times weaker than geomagnetic field (GMF). It is well known that microgravity in space can induce bone loss; however, it is ill-defined whether HyMF involved in this process. Herein, we aimed to investigate the combined effects of HyMF and microgravity on bone loss. A mouse model of hindlimb suspension (HLU) was adopted to simulate microgravity-induced bone loss, that was exposed to a hypomagnetic field of <300 nanotesla (nT) generated by a geomagnetic field-shielding chamber...
June 18, 2018: Bone
Christopher Strouse, Ying Zhang, Mei-Jie Zhang, Alyssa DiGilio, Marcelo Pasquini, Mary M Horowitz, Stephanie Lee, Vincent Ho, Muthalagu Ramanathan, Wichai Chinratanalab, Alison Loren, Linda J Burns, Andrew Artz, Kathleen F Villa, Wael Saber
BACKGROUND: A risk score identifying patients at high risk for veno-occlusive disease (VOD) may aid efforts to study preventive strategies for this uncommon complication of hematopoietic cell transplantation (HCT). METHODS: Patients receiving a first allogeneic HCT between 2008-2013 as reported to the Center for International Blood & Marrow Transplant Research (N=13,097) were randomly divided into training and validation sets. Independent prognostic factors for development of VOD by day+100 post HCT were identified with a multivariate logistic regression model...
June 18, 2018: Biology of Blood and Marrow Transplantation
Ibragim Gaidarov, John Adams, John Frazer, Todd Anthony, Xiaohua Chen, Joel Gatlin, Graeme Semple, David J Unett
Angiotensin (1-7) has been reported to be a ligand for the GPCR MAS1. Small molecule MAS1 modulators have also been recently characterized. Aside from convincing evidence for MAS1 activation of Gq signaling, little is known about MAS1 mediated signaling pathways initiated by these ligands, especially Ang (1-7). We performed a comprehensive characterization of recombinant MAS1 signaling induced by Ang (1-7) and small molecule ligands through numerous G protein-dependent and independent pathways, and in a signaling pathway agnostic approach...
June 18, 2018: Cellular Signalling
Annelies Smeets, Robin Koekoekx, Christian Clasen, Guy Van den Mooter
The interest in using electrospraying as a manufacturing method for amorphous solid dispersions has grown remarkably. However, the impact of formulation and process parameters needs further clarification. In this study, amorphous solid dispersions of darunavir and hydroxypropyl methylcellulose (HPMC), hydroxypropyl methylcellulose acetate succinate (HPMC AS) and polyvinylpyrrolidone K-30 (PVP) were prepared with electrospraying and spray drying, in order to compare both solvent based manufacturing techniques...
June 18, 2018: European Journal of Pharmaceutics and Biopharmaceutics
J Mustofa, P-Y Cheung, S Patel, T F Lee, M Lu, M P Pasquin, M OʼReilly, G M Schmölzer
OBJECTIVE: We previously demonstrated that sustained inflation (SI) during chest compression (CC) significantly reduces time to return of spontaneous circulation (ROSC) when compared to 3:1 compression:ventilation (C:V) ratio during neonatal resuscitation. However, the optimal length of SI during CC to improve ROSC and hemodynamic recovery in severely asphyxiated piglets is unknown. AIM: To examine if different lengths of SI will improve ROSC and hemodynamic recovery in severely asphyxiated piglets...
June 18, 2018: Resuscitation
Ling Qian, Shulin Yu, Zhen Chen, Zhiqiang Meng, Shenglin Huang, Peng Wang
Circular RNA (circRNA), a recently discovered subclass of non-coding RNAs (ncRNAs), forms a covalently closed loop with neither a 5' cap structure nor a 3' polyadenylated tail. Generated from precursor mRNA (pre-mRNA) through "backsplicing" (a type of alternative RNA splicing), the majority of circRNAs are located in the cytoplasm and are widespread among living organisms. They are stable and conserved and exhibit spatiotemporal-specific expression. circRNAs are known to be involved in the development and progression of multiple diseases, including cancer, by acting as microRNA (miRNA) sponges and by regulating processes such as transcription and translation...
June 18, 2018: Biochimica et Biophysica Acta
Shane R Stecklein, Minjeong Park, Diane D Liu, Janeiro J Valle Goffin, Abigail S Caudle, Elizabeth A Mittendorf, Carlos H Barcenas, Sarah Mougalian, Wendy A Woodward, Vicente Valero, Aysegul A Sahin, Wei T Yang, Simona F Shaitelman
BACKGROUND: The impact of regional nodal irradiation (RNI) on locoregional recurrence (LRR) and any disease recurrence (DR) in women with node-positive breast cancer who receive neoadjuvant systemic therapy (NAT) is unknown. METHODS: The impact of RNI on LRR and DR was estimated with the cumulative incidence method in 1289 women with stage II-III breast cancer with cytologically confirmed axillary metastases who received NAT, 1989-2007. Multicovariate Cox regression analysis was performed to examine the effect of RNI after accounting for other predictive and prognostic variables...
June 18, 2018: International Journal of Radiation Oncology, Biology, Physics
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"