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https://www.readbyqxmd.com/read/28325036/microwave-hydrothermal-synthesis-of-terbium-ions-complexed-with-porous-graphene-for-effective-absorbent-for-organic-dye
#1
Keqin Chen, Hui Gao, Bowei Bai, Wenjing Liu, Xiaolong Li
A luminescent terbium ions/reduced graphene oxide complex (Tb-RGO) was successfully and rapidly synthesized by the microwave hydrothermal reaction via the interactions between terbium ions and the active oxygen functional groups of graphene oxide. The as-prepared material was porous stacked by multilayer graphene in all directions. Thus, the resulting product owed the high specific surface area, high adsorption capacity and ultra-fast adsorption rate. Combined with the characteristic photoluminescence derived from terbium ions, the material has potential applications in biosensing and environmental protection...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28324991/features-of-cerebral-oxygenation-detects-brain-injury-in-premature-infants
#2
John M O'Toole, Mmoloki Kenosi, Daragh Finn, Geraldine B Boylan, Eugene M Dempsey
Babies born prematurely can develop brain injury within days after birth. Early identification of high-risk infants enables appropriate clinical care to mitigate potential lifelong disabilities. Near infra-red spectroscopy is an established technology that can provide continuous measurements of cerebral oxygen saturation (rcSO2) over this critical period. We develop a feature set of the rcSO2 signal for the purpose of detecting brain injury. Our feature set contains amplitude, spectral, and fractal dimension features within 5 frequency bands...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324986/electrocardiographic-waveforms-fitness-check-device-technique-for-sudden-cardiac-death-risk-screening
#3
O J Escalona, M Mendoza
A novel cardiac health device technique development for reliable, non-invasive and cost-effective heart screening in preventive cardiovascular healthcare is presented. In particular, identification of apparently healthy individuals involved in sports activities (particularly in the young, age <; 35 years) who may be at-risk of sudden-cardiac-death (SCD) is mainly focused here. Nevertheless, the same device technique may be prospectively extended for detecting cardiovascular abnormalities in children and adolescents with type1-diabetes, and also in detecting patients with Brugada syndrome...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324972/analysis-of-spontaneous-eeg-activity-in-alzheimer-s-disease-using-cross-sample-entropy-and-graph-theory
#4
Carlos Gomez, Jesus Poza, Javier Gomez-Pilar, Alejandro Bachiller, Celia Juan-Cruz, Miguel A Tola-Arribas, Alicia Carreres, Monica Cano, Roberto Hornero
The aim of this pilot study was to analyze spontaneous electroencephalography (EEG) activity in Alzheimer's disease (AD) by means of Cross-Sample Entropy (Cross-SampEn) and two local measures derived from graph theory: clustering coefficient (CC) and characteristic path length (PL). Five minutes of EEG activity were recorded from 37 patients with dementia due to AD and 29 elderly controls. Our results showed that Cross-SampEn values were lower in the AD group than in the control one for all the interactions among EEG channels...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324966/random-forests-to-predict-tumor-recurrence-following-cervical-cancer-therapy-using-pre-and-per-treatment-18-f-fdg-pet-parameters
#5
Geoffrey Roman-Jimenez, Oscar Acosta, Julie Leseur, Anne Devillers, Henri Der Sarkissian, Lina Guzman, Eloi'se Grossiord, Juan-David Ospina, Renaud De Crevoisier
The ability to predict tumor recurrence after chemoradiotherapy of locally advanced cervical cancer is a crucial clinical issue to intensify the treatment of the most high-risk patients. The objective of this study was to investigate tumor metabolism characteristics extracted from pre- and per-treatment (18)F-FDG PET images to predict 3-year overall recurrence (OR). A total of 53 locally advanced cervical cancer patients underwent pre- and per-treatment (18)F-FDG PET (respectively PET1 and PET2). Tumor metabolism was characterized through several delineations using different thresholds, based on a percentage of the maximum uptake, and applied by region-growing...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324944/biclustering-strategies-for-genetic-marker-selection-in-gynecologic-tumor-cell-lines
#6
A Alevyzaki, S Sfakianakis, E S Bei, E Obermayr, R Zeillinger, D Fotiadis, M Zervakis
Over the past few decades great interest has been focused on cell lines derived from tumors, because of their usability as models to understand the biology of cancer. At the same time, advanced technologies such as DNA-microarrays have been broadly used to study the expression level of thousands of genes in primary tumors or cancer cell lines in a single experiment. Results from microarray analysis approaches have provided valuable insights into the underlying biology and proven useful for tumor classification, prognostication and prediction...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324942/quantitative-analysis-of-histological-tissue-image-based-on-cytological-profiles-and-spatial-statistics
#7
Young Hwan Chang, Guillaume Thibault, Vahid Azimi, Brett Johnson, Danielle Jorgens, Jason Link, Adam Margolin, Joe W Gray
The cellular heterogeneity and complex tissue architecture of most tumor samples is a major obstacle in image analysis on standard hematoxylin and eosin-stained (H&E) tissue sections. A mixture of cancer and normal cells complicates the interpretation of their cytological profiles. Furthermore, spatial arrangement and architectural organization of cells are generally not reflected in cellular characteristics analysis. To address these challenges, first we describe an automatic nuclei segmentation of H&E tissue sections...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324887/association-between-hypoxic-volume-and-underlying-hypoxia-induced-gene-expression-in-oropharyngeal-squamous-cell-carcinoma
#8
Yae-Eun Suh, Katherine Lawler, Rhonda Henley-Smith, Lucy Pike, Russell Leek, Sally Barrington, Edward W Odell, Tony Ng, Francesco Pezzella, Teresa Guerrero-Urbano, Mahvash Tavassoli
BACKGROUND: Hypoxia imaging is a promising tool for targeted therapy but the links between imaging features and underlying molecular characteristics of the tumour have not been investigated. The aim of this study was to compare hypoxia biomarkers and gene expression in oropharyngeal squamous cell carcinoma (OPSCC) diagnostic biopsies with hypoxia imaged with (64)Cu-ATSM PET/CT. METHODS: (64)Cu-ATSM imaging, molecular and clinical data were obtained for 15 patients...
March 21, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28324873/endobronchial-ultrasound-elastography-for-evaluation-of-intrathoracic-lymph-nodes-a-pilot-study
#9
Jiayuan Sun, Xiaoxuan Zheng, Xiaowei Mao, Lei Wang, Hongkai Xiong, Felix J F Herth, Baohui Han
BACKGROUND: Endobronchial ultrasound (EBUS) elastography is a new imaging procedure for describing the elasticity of intrathoracic lesions and providing important additional diagnostic information. OBJECTIVES: The aim of this study was to utilize the feasibility of qualitative and quantitative methods to evaluate the ability of EBUS elastography to differentiate between benign and malignant mediastinal and hilar lymph nodes (LNs) during EBUS-guided transbronchial needle aspiration (EBUS-TBNA)...
March 22, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28324871/herd-specific-random-regression-carcass-profiles-for-beef-cattle-after-adjustment-for-animal-genetic-merit
#10
Tanya M Englishby, Kirsty L Moore, Donagh P Berry, Mike P Coffey, Georgios Banos
Abattoir data are an important source of information for the genetic evaluation of carcass traits, but also for on-farm management purposes. The present study aimed to quantify the contribution of herd environment to beef carcass characteristics (weight, conformation score and fat score) with particular emphasis on generating finishing herd-specific profiles for these traits across different ages at slaughter. Abattoir records from 46,115 heifers and 78,790 steers aged between 360 and 900days, and from 22,971 young bulls aged between 360 and 720days, were analysed...
March 7, 2017: Meat Science
https://www.readbyqxmd.com/read/28324868/lactic-acid-concentrations-that-reduce-microbial-load-yet-minimally-impact-colour-and-sensory-characteristics-of-beef
#11
Cristina Rodríguez-Melcón, Carlos Alonso-Calleja, Rosa Capita
Lactic acid (LA) has recently been approved in the EU as beef decontaminant. In order to identify the most appropriate concentration, beef samples were spray-treated with LA (2%, 3%, 4% or 5%) or left untreated (control). Microbial load (aerobic plate counts, psychrotrophs and Enterobacteriaceae), pH, instrumental colour and sensory properties were investigated at 0, 24, 72 and 120h of refrigerated storage. The reductions in bacteria after spraying ranged from 0.57 to 0.95 log units. A residual antimicrobial effect was observed so that at 120h LA reduced microbial load by up to 2 log units compared with the control samples...
January 17, 2017: Meat Science
https://www.readbyqxmd.com/read/28324866/long-term-bioavailability-of-redox-nanoparticles-effectively-reduces-organ-dysfunctions-and-death-in-whole-body-irradiated-mice
#12
Chitho P Feliciano, Koji Tsuboi, Kenshi Suzuki, Hiroyuki Kimura, Yukio Nagasaki
Radioprotective agents have been developed to protect patients against the damaging and lethal effects of ionizing radiation. However, in addition to the intrinsic ability to target reactive oxygen species (ROS), the ability to retain a significant level of bioavailability is desirable in radioprotective agents because that would increase and prolong their radioprotective efficacy and improve its safety. Here, we report the development of a novel nanoparticle-based radioprotective agent with improved bioavailability, which suppressed the adverse effects typically associated with low-molecular-weight (LMW) antioxidants...
March 14, 2017: Biomaterials
https://www.readbyqxmd.com/read/28324860/direct-detection-of-two-different-tumor-derived-extracellular-vesicles-by-sam-aunis-lspr-biosensor
#13
Abhimanyu Thakur, Guangyu Qiu, Siu-Pang Ng, Jintao Guan, Jianbo Yue, Youngjin Lee, Chi-Man Lawrence Wu
Extracellular vesicles (EVs) are abundant in various biological fluids including blood, saliva, urine, as well as extracellular milieu. Accumulating evidence has indicated that EVs, which contain functional proteins and small RNAs, facilitate intercellular communication between neighbouring cells, and are critical to maintain various physiological processes. In contrast, EV-derived toxic signals can spread out over the tissues adjacent to the injured area in certain diseases, including brain tumors and neurodegenerative disorders...
March 18, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28324843/variations-in-pu-isotopic-composition-in-soils-from-the-spitsbergen-norway-three-potential-pollution-sources-of-the-arctic-region
#14
E Łokas, R Anczkiewicz, R Kierepko, J W Mietelski
Although the polar regions have not been industrialised, numerous contaminants originating from human activity are detectable in the Arctic environment. This study reports evidence of (240)Pu/(239)Pu atomic ratios in the tundra and initial soils from different parts of west and central Spitsbergen and recognizes possible environmental inputs of non-global fallout Pu. The average atomic ratio of (240)Pu/(239)Pu equal to 0.179 (ranging between 0.129 and 0.201) in tundra soils are comparable to the characteristic ratio for global fallout (0...
March 18, 2017: Chemosphere
https://www.readbyqxmd.com/read/28324791/spatio-temporal-neighborhood-impacts-on-internalizing-and-externalizing-behaviors-in-u-s-elementary-school-children-effect-modification-by-child-and-family-socio-demographics
#15
Jamie L Humphrey, Elisabeth D Root
Increasing evidence from experimental and non-experimental research has shown that children residing in disadvantaged neighborhoods exhibit greater levels of internalizing and externalizing behaviors, above and beyond individual characteristics, and family or school contexts. Using the ECLS-K, a nationally representative, longitudinal survey of U.S. school children, this study examined direct neighborhood effects on internalizing (N = 14,870; N = 10,610) and externalizing (N = 14,960; N = 10,730) behaviors at the beginning and end of elementary school...
March 12, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28324788/primary-central-nervous-system-vasculitis-and-its-mimicking-diseases-clinical-features-outcome-comorbidities-and-diagnostic-results-a-case-control-study
#16
J Becker, P A Horn, K Keyvani, I Metz, C Wegner, W Brück, F M Heinemann, J C Schwitalla, P Berlit, M Kraemer
OBJECTIVES: To compare clinical features and outcome, imaging characteristics, biopsy results and laboratory findings in a cohort of 69 patients with suspected or diagnosed primary central nervous system vasculitis (PCNSV) in adults; to identify risk factors and predictive features for PCNSV. PATIENTS AND METHODS: We performed a case-control-study including 69 patients referred with suspected PCNSV from whom 25 were confirmed by predetermined diagnostic criteria based on biopsy (72%) or angiography (28%)...
March 8, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28324783/recent-updates-of-carbapenem-antibiotics
#17
REVIEW
Mohammed I El-Gamal, Imen Brahim, Noorhan Hisham, Rand Aladdin, Haneen Mohammed, Amany Bahaaeldin
Carbapenems are among the most commonly used and the most efficient antibiotics since they are relatively resistant to hydrolysis by most β-lactamases, they target penicillin-binding proteins, and generally have broad-spectrum antibacterial effect. In this review, we described the initial discovery and development of carbapenems, chemical characteristics, in vitro/in vivo activities, resistance studies, and clinical investigations for traditional carbapenem antibiotics in the market; imipenem-cilastatin, meropenem, ertapenem, doripenem, biapenem, panipenem/betamipron in addition to newer carbapenems such as razupenem, tebipenem, tomopenem, and sanfetrinem...
March 16, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28324781/genesis-and-properties-of-wetland-soils-by-vis-nir-swir-as-a-technique-for-environmental-monitoring
#18
José Alexandre Melo Demattê, Ingrid Horák-Terra, Raphael Moreira Beirigo, Fabrício da Silva Terra, Karina Patrícia Prazeres Marques, Caio Troula Fongaro, Alexandre Christófaro Silva, Pablo Vidal-Torrado
Wetlands are important ecosystems characterized by redoximorphic environments producing typical soil forming processes and organic carbon accumulation. Assessments and management of these areas are dependent on knowledge about soil characteristics and variability. By reflectance spectroscopy, information about soils can be obtained since their spectral behaviors are directly related to their chemical, physical, and mineralogical properties reflecting the pedogenetic processes and environment conditions. Our aims were: (a) to characterize the main soil classes of wetlands regarding their spectral behaviors in VIS-NIR-SWIR (350-2500 nm) and relate them to pedogenesis and environmental conditions, (b) to determine spectral ranges (bands) with greater expression of the main soil properties, (c) to identify spectral variations and similarities between hydromorphic soils from wetlands and other soils under different moisture conditions, and (d) to propose spectral models to quantify some chemical and physical soil properties used as environmental quality indicators...
March 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28324772/new-proposals-of-the-who-working-group-2016-for-the-diagnosis-of-myelodysplastic-syndromes-mds-characteristics-of-refined-mds-types
#19
Corinna Strupp, Kathrin Nachtkamp, Barbara Hildebrandt, Aristoteles Giagounidis, Rainer Haas, Norbert Gattermann, John M Bennett, Carlo Aul, Ulrich Germing
Based on centrally diagnosed 3528 patients in the Düsseldorf registry, we validated the new proposals for the classification of the MDS by the WHO working group: 256 patients were diagnosed as MDSSLD (7,3%), 978 MDSMLD (27,7%), 227 MDS RS SLD (6,4%); 321 MDS RS MLD (9,1%), 159 MDS del(5q) (4,5%), 481 MDSEB 1 (13,6%), 620 MDSEB 2 (17,6%), and 148 MDS-U (4,2%). 352 patients (16,9% of the non blastic types) changed the category, mainly moving from RCMD to MDS RS MLD, RCUD and RCMD to MDS del(5q). Median survival times of the refined groups differed from more than 60 months in the MDSSLD (RS) groups, 37 months in the MDSMLD (RS) groups, 79 months of the MDS del(5q) group and 21 and 11 months in the MDSEB 1 and 2 groups, respectively...
February 27, 2017: Leukemia Research
https://www.readbyqxmd.com/read/28324747/optimal-dose-reduction-of-folfirinox-for-preserving-tumour-response-in-advanced-pancreatic-cancer-using-cumulative-relative-dose-intensity
#20
Jong-Chan Lee, Jin Won Kim, Soyeon Ahn, Hyoung Woo Kim, Jongchan Lee, Young Hoon Kim, Kyu-Hyun Paik, Jaihwan Kim, Jin-Hyeok Hwang
BACKGROUND: FOLFIRINOX has increased efficacy but also toxicity. Despite various modified FOLFIRINOX regimens, how much reduction is acceptable remains unclear. This study aimed to find the optimal relative dose intensity (RDI, %) of FOLFIRINOX that preserves tumour responses in patients with advanced pancreatic cancer (PC). METHODS: We reviewed 201 patients with PC treated with first-line FOLFIRINOX during 2012-2015. We established a modified Hryniuk model (http://www...
March 16, 2017: European Journal of Cancer
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