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https://www.readbyqxmd.com/read/28440507/a-novel-splice-site-mutation-of-wrn-c-ivs28-2t-c-identified-in-a-consanguineous-family-with-werner-syndrome
#1
Pan-Feng Wu, Jie-Yuan Jin, Jing-Jing Li, Ji-Qiang He, Liang-Liang Fan, Min Jin, Hao Huang, Kun Xia, Ju-Yu Tang, Rong Xiang
Werner Syndrome (WS) is a rare, adult‑onset progeroid syndrome that is associated with multiple age‑associated complications and relatively short life expectancy. The characteristics of WS include a 'bird‑like' appearance, canities, cataracts and ulcerations around the ankles. In addition, certain patients develop hypogonadism with atrophic genitalia and infertility. The average life span of affected individuals is 54 years. Previous studies have demonstrated that mutations in the Werner syndrome RecQ like helicase gene (WRN) may contribute to WS...
April 12, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28439470/mitochondrial-diversity-in-gonionemus-trachylina-hydrozoa-and-its-implications-for-understanding-the-origins-of-clinging-jellyfish-in-the-northwest-atlantic-ocean
#2
Annette F Govindarajan, Mary R Carman, Marat R Khaidarov, Alexander Semenchenko, John P Wares
Determining whether a population is introduced or native to a region can be challenging due to inadequate taxonomy, the presence of cryptic lineages, and poor historical documentation. For taxa with resting stages that bloom episodically, determining origin can be especially challenging as an environmentally-triggered abrupt appearance of the taxa may be confused with an anthropogenic introduction. Here, we assess diversity in mitochondrial cytochrome oxidase I sequences obtained from multiple Atlantic and Pacific locations, and discuss the implications of our findings for understanding the origin of clinging jellyfish Gonionemus in the Northwest Atlantic...
2017: PeerJ
https://www.readbyqxmd.com/read/28437651/population-attributable-risk-associated-with-lung-cancer-induced-by-residential-radon-in-canada-sensitivity-to-relative-risk-model-and-radon-probability-density-function-choices-in-memory-of-professor-jan-m-zielinski
#3
Mo'tassem Al-Arydah
Indoor radon has been identified as the second leading cause of lung cancer after tobacco smoking. The Population Attributable Risk (PAR) estimates the proportion of lung cancer cases associated with indoor radon exposure. Different relative risk (RR) models have been used in the literature to calculate PAR. The aim of this study is to assess how sensitive PAR is to the relative risk model and radon probability distribution functions choices. METHODS: Using Canadian observed first floor radon data collected by Health Canada during the period October 2010 to March 2011, seven common PAR radon models used for North American miners and dwelling scenarios were applied...
April 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28437646/combined-effects-of-climate-restoration-measures-and-slope-position-in-change-in-soil-chemical-properties-and-nutrient-loss-across-lands-affected-by-the-wenchuan-earthquake-in-china
#4
Yongming Lin, Haojun Deng, Kun Du, Loretta Rafay, Guang-Shuai Zhang, Jian Li, Can Chen, Chengzhen Wu, Han Lin, Wei Yu, Hailan Fan, Yonggang Ge
The MS 8.0Wenchuan Earthquake in 2008 caused huge damage to land cover in the northwest of China's Sichuan province. In order to determine the nutrient loss and short term characteristics of change in soil chemical properties, we established an experiment with three treatments ('undestroyed', 'destroyed and treated', and 'destroyed and untreated'), two climate types (semi-arid hot climate and subtropical monsoon climate), and three slope positions (upslope, mid-slope, and bottom-slope) in 2011. Ten soil properties-including pH, organic carbon, total nitrogen, total phosphorus, total potassium, Ca(2+), Mg(2+), alkaline hydrolysable nitrogen, available phosphorus, and available potassium-were measured in surface soil samples in December 2014...
April 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28437593/tabula-rasa-in-the-patagonian-channels-the-phylogeography-of-oreobolus-obtusangulus-cyperaceae
#5
Simon Pfanzelt, Dirk C Albach, Klaus Bernhard von Hagen
The extent of the Pleistocene glaciations in the Patagonian Channel region (southwesternmost South America) and their impact on the vegetation there is largely unknown. Whether the regional flora was wiped out completely (tabula rasa) or survived in ice-free pockets (in situ survival) is still an open question. The molecular imprint of either scenario should still be visible in extant populations. Therefore, DNA sequence data of Oreobolus obtusangulus Gaudich. (Cyperaceae) were analyzed. This species is an abundant constitutent of Patagonian cushion peat bogs, one of the Patagonian Channel region's major vegetation types...
April 24, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28437407/the-elusive-northwest-passage
#6
Katie Peek
No abstract text is available yet for this article.
April 18, 2017: Scientific American
https://www.readbyqxmd.com/read/28435817/molecular-and-morphometrical-characterization-of-fasciola-species-isolated-from-domestic-ruminants-in-ardabil-province-northwestern-iran
#7
Mojgan Aryaeipour, Arezoo Bozorgomid, Bahram Kazemi, Masoud Behnia, Hakim Azizi, Mohammad Bagher Rokni
BACKGROUND: We aimed to describe morphological and morphometrical characteristics of Fasciola spp. in livestock from Ardabil Province, Northwest Iran. METHODS: Forty adult flukes were collected from different definitive hosts (cattle and sheep). Previously specimens were identified as F. hepatica or F. gigantica based on PCR-RFLP of the ITS-1 region with RsaI enzyme. We identified Fasciola spp. based on morphological and metric assessment of external features of fresh adults, morphological and metric assessment of internal anatomy of stained mounted worms...
March 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28434736/incidence-of-clinical-mastitis-and-distribution-of-pathogens-on-large-chinese-dairy-farms
#8
Jian Gao, Herman W Barkema, Limei Zhang, Gang Liu, Zhaoju Deng, Lingjie Cai, Ruixue Shan, Shiyao Zhang, Jiaqi Zou, John P Kastelic, Bo Han
Knowledge of the incidence of clinical mastitis (CM) and the distribution of pathogens involved is essential for development of prevention and control programs as well as treatment protocols. No country-wide study on the incidence of CM and the distribution of pathogens involved has been conducted in China. Core objectives of this study were, therefore, to determine the cumulative incidence of CM and the distribution of pathogens causing CM on large Chinese (>500 cows) dairy farms. In addition, associations between the distribution of CM pathogens and bedding materials and seasonal factors were also investigated...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28434030/spatial-and-temporal-distributions-of-air-pollutants-and-size-distribution-of-aerosols-over-central-and-eastern-china
#9
Honglei Wang, Lijuan Shen, Bin Zhu, Hanqing Kang, Xuewei Hou, Qing Miao, Yang Yang, Shuangshuang Shi
The origins and spatial and temporal distributions of air pollutants (PM2.5, PM10, CO, SO2, NO2 and O3) during May to June of 2015 were investigated using data from 1490 monitoring sites in China. Aerosol number concentrations and meteorological data from Shijiazhuang, Nanjing, and Suzhou were combined with the MIX Asian emission data and the HYSPLIT model. Furthermore, the diurnal variation, size distribution, and main sources of air pollutants and aerosols were selectively characterized in the North China Plain (NCP) and the Yangtze River Delta (YRD)...
April 22, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28433768/response-of-evapotranspiration-to-changes-in-land-use-and-land-cover-and-climate-in-china-during-2001-2013
#10
Gen Li, Fangmin Zhang, Yuanshu Jing, Yibo Liu, Ge Sun
Land surface evapotranspiration (ET) is a central component of the Earth's global energy balance and water cycle. Understanding ET is important in quantifying the impacts of human influences on the hydrological cycle and thus helps improving water use efficiency and strengthening water use planning and watershed management. China has experienced tremendous land use and land cover changes (LUCC) as a result of urbanization and ecological restoration under a broad background of climate change. This study used MODIS data products to analyze how LUCC and climate change affected ET in China in the period 2001-2013...
April 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28428843/rad-sequencing-reveals-genomewide-divergence-between-independent-invasions-of-the-european-green-crab-carcinus-maenas-in-the-northwest-atlantic
#11
Nicholas W Jeffery, Claudio DiBacco, Mallory Van Wyngaarden, Lorraine C Hamilton, Ryan R E Stanley, Renée Bernier, Jennifer FitzGerald, K Matheson, C H McKenzie, Praveen Nadukkalam Ravindran, Robert Beiko, Ian R Bradbury
Genomic studies of invasive species can reveal both invasive pathways and functional differences underpinning patterns of colonization success. The European green crab (Carcinus maenas) was initially introduced to eastern North America nearly 200 years ago where it expanded northwards to eastern Nova Scotia. A subsequent invasion to Nova Scotia from a northern European source allowed further range expansion, providing a unique opportunity to study the invasion genomics of a species with multiple invasions...
April 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28428798/plastic-film-mulching-for-enhanced-water-use-efficiency-and-economic-returns-from-maize-fields-in-semiarid-china
#12
Peng Zhang, Ting Wei, Tie Cai, Shahzad Ali, Qingfang Han, Xiaolong Ren, Zhikuan Jia
Film mulch has gradually been popularized to increase water availability to crops for improving and stabilizing agricultural production in the semiarid areas of Northwest China. To find more sustainable and economic film mulch methods for alleviating drought stress in semiarid region, it is necessary to test optimum planting methods in same cultivation conditions. A field experiment was conducted during 2013 and 2014 to evaluate the effects of different plastic film mulch methods on soil water, soil temperature, water use efficiency (WUE), yield and revenue...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28427368/complications-of-miliary-tuberculosis-low-mortality-and-predictive-biomarkers-from-a-uk-cohort
#13
Jonathan Underwood, Fiona Cresswell, Alex P Salam, Alex J Keeley, Charles Cleland, Laurence John, Robert N Davidson
BACKGROUND: Untreated, miliary tuberculosis (TB) has a mortality approaching 100%. As it is uncommon there is little specific data to guide its management. We report detailed data from a UK cohort of patients with miliary tuberculosis and the associations and predictive ability of admission blood tests with clinical outcomes. METHODS: Routinely collected demographic, clinical, blood, imaging, histopathological and microbiological data were assessed for all patients with miliary TB identified from the London TB register from 2008 to 2012 from Northwest London Hospitals NHS Trust...
April 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28426548/the-medex-northwest-physician-assistant-program-a-synopsis
#14
Kevin Lohenry
No abstract text is available yet for this article.
April 19, 2017: Journal of Physician Assistant Education
https://www.readbyqxmd.com/read/28424562/immunological-and-hematological-reference-intervals-among-hiv-seronegative-pregnant-women-in-northwest-ethiopia
#15
Meaza Genetu, Debasu Damtie, Meseret Workineh, Biniam Mathewos Tebeje, Bamlaku Enawgaw, Tekalign Deressa
BACKGROUND: Pregnancy is a state characterized by profound physiological hematological changes. However, hematological reference intervals being used in clinical practice in Ethiopia are derived from nonlocal general populations, despite the significant variations reported previously. The aim of this study was to determine the immunological and hematological reference intervals in healthy pregnancy among HIV-seronegative pregnant women in northwest Ethiopia. MATERIALS AND METHODS: A total of 200 healthy, HIV-seronegative pregnant women were enrolled from February 2015 to June 2015 in a cross-sectional study setting at Gondar University Hospital...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28424424/leukocyte-telomere-length-related-genetic-variants-in-acyp2-contribute-to-the-risk-of-esophageal-carcinoma-in-chinese-han-population
#16
Quan Fang, Lihong Hui, Zhaorui Min, Lifeng Liu, Yuan Shao
BACKGROUND: Short leukocyte telomere length has been associated with significantly increased risk of esophageal carcinoma. A previous genome-wide association study demonstrated that ACYP2 was associated with leukocyte telomere length. However, the role of ACYP2 genetic variants on esophageal carcinoma susceptibility is still unknown. Therefore, we investigated whether ACYP2 polymorphisms have impact on the risk of esophageal carcinoma in Chinese. MATERIALS AND METHODS: We conducted a case-control study among 386 cases and 495 healthy controls from northwest China...
March 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28422982/assessment-ecological-risk-of-heavy-metal-caused-by-high-intensity-land-reclamation-in-bohai-bay-china
#17
Gaoru Zhu, Zhenglei Xie, Tuoyu Li, Zongwen Ma, Xuegong Xu
The article examines the detailed spatial and temporal distributions of coastal reclamation in the northwest coast of Bohai Bay experiencing rapid coastal reclamation in China from 1974 to 2010 in annual intervals. Moreover, soil elements properties and spatial distribution in reclaimed area and inform the future coastal ecosystems management was also analyzed. The results shows that 910.7 km2 of coastal wetlands have been reclaimed and conversed to industrial land during the past 36 years. It covers intertidal beach, shallow sea and island with a percentage of 76...
2017: PloS One
https://www.readbyqxmd.com/read/28422135/genomic-evidence-of-hybridization-between-two-independent-invasions-of-european-green-crab-carcinus-maenas-in-the-northwest-atlantic
#18
N W Jeffery, C DiBacco, B F Wringe, R R E Stanley, L C Hamilton, P N Ravindran, I R Bradbury
Invasive species have been associated with significant negative impacts in their introduced range often outcompeting native species, yet the long-term evolutionary dynamics of biological invasions are not well understood. Hybridization, either among waves of invasion or between native and introduced populations, could alter the ecological and evolutionary impacts of invasions yet has rarely been studied in marine invasive species. The European green crab (Carcinus maenas) invaded eastern North America twice from northern and southern locations in its native range...
April 19, 2017: Heredity
https://www.readbyqxmd.com/read/28421270/climate-variability-impacts-on-rainfed-cereal-yields-in-west-and-northwest-iran
#19
Milad Nouri, Mehdi Homaee, Mohammad Bannayan
In order to assess the response of wheat and barley to climate variability, the correlation between variations of yields with local and global climate variables was investigated in west and northwest Iran over 1982-2013. The global climate variables were the El Niño-Southern Oscillation (ENSO), Arctic Oscillation (AO), and North Atlantic Oscillation (NAO) signals. Further, minimum (T min), maximum (T max), and mean (T mean) temperature, diurnal temperature range (DTR), precipitation, and reference evapotranspiration (ET0) was used as local weather factors...
April 18, 2017: International Journal of Biometeorology
https://www.readbyqxmd.com/read/28420380/educational-status-as-determinant-of-men-s-knowledge-about-vasectomy-in-dangila-town-administration-amhara-region-northwest-ethiopia
#20
Abrham Jemberie Temach, Gedefaw Abeje Fekadu, Anemaw Asrat Achamyeleh
BACKGROUND: Although vasectomy is effective and less expensive contraceptive method, only few men are using it in Africa. The main reason for low level use may be low knowledge about vasectomy among men. Only few studies tried to investigate level of knowledge of vasectomy among married men in Ethiopia. But these studies have limitations in measuring knowledge. This study was therefore designed to assess knowledge of vasectomy among married men in Dangila town. METHOD: A community based cross sectional study was conducted in Dangila town...
April 18, 2017: Reproductive Health
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