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https://www.readbyqxmd.com/read/29685610/review-of-the-evidence-on-handling-drugs-and-hazardous-products-in-urology-departments-consensus-document-between-the-spanish-urological-association-and-the-spanish-society-of-hospital-pharmacy
#1
M Unda-Urzaiz, J M Alonso-Herreros, J M Fernandez-Gomez, M Gaspar-Carreño, J M Cozar-Olmos, A C Cercós Lleti
BACKGROUND: The intravesical administration of hazardous drug products is a standard practice in the urology setting, which potentially exposing medical personnel to these drug products. It was deemed necessary to have a consensus document among the scientific societies involved (the Spanish Urological Association and the Spanish Society of Hospital Pharmacy) that collects the best available evidence on the safest handling possible of dangerous drug products in the setting of urology departments...
April 20, 2018: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29684957/-iatrogenic-injuries-of-urinary-tract-outcomes-of-surgical-repairs
#2
Yoshiaki Matsumura, Yusuke Iemura, Shinji Fukui, Yoriaki Kagebayashi, Shoji Samma
Iatrogenic urinary tract injuries are known complications of digestive and pelvic surgeries. We retrospectively reviewed 13 patients with bladder injuries and 16 patients with ureteral injuries requiring surgical repair or stent placement in our hospital between 2013 and 2016. Obstetric-gynecologic surgery accounted for 10 bladder injuries and 11 ureteral injuries on hysterectomy and Cesarean section. Digestive surgery led to 1 bladder injury and 5 ureteral injuries on colon resection, and urologic surgery resulted in 1 injury on biopsy of a retroperitoneal tumor...
March 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29684956/-clinical-utility-of-upper-urinary-tract-reconstruction-by-ileal-ureter-substitution
#3
Yoshinaga Okumura, Shusuke Akamatsu, Yoshiyuki Okada, Hiromitsu Negoro, Takashi Kobayashi, Naoki Terada, Toshinari Yamasaki, Yoshiyuki Matsui, Takahiro Inoue, Tomomi Kamba, Osamu Ogawa
We retrospectively reviewed the indications and outcomes of ileal-ureter substitution cases for complex ureteral reconstruction. We analyzed the patient clinical characteristics, outcomes, and complications of eight patients who had ileal ureter substitution surgery at Kyoto University Hospital between 2009 and 2016. The median patient age was 55.5 years (36-79), and the median follow up period was 25.5 months (7-85). Seven patients had unilateral ureteral obstruction (right:left=4:3), and one had bilateral ureteral obstruction...
March 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29680953/surgical-management-of-the-neurogenic-bladder-after-spinal-cord-injury
#4
Jean-Jacques Wyndaele, Brian Birch, Albert Borau, Frank Burks, David Castro-Diaz, Emmanuel Chartier-Kastler, Marcus Drake, Osamu Ishizuka, Tomonori Minigawa, Eloy Opisso, Kenneth Peters, Barbara Padilla-Fernández, Christine Reus, Noritoshi Sekido
PURPOSE: This work represents the efforts of the SIU-ICUD workgroup on this topic and comprehensive literature search of English language manuscripts regarding urologic surgery in spinal cord injury using key words of urologic surgery and spinal cord injury. Articles were compiled, and recommendations in the chapter are based on group discussion and intensive communication. The purpose is to review what has been published during the last decades on urological surgery for neurogenic bladder after spinal cord injury...
April 21, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29680275/can-sacral-development-as-a-marker-for-caudal-regression-help-identify-associated-urologic-anomalies-in-patients-with-anorectal-malformation
#5
Alejandra Vilanova-Sanchez, Carlos A Reck, Yuri V Sebastião, Molly Fuchs, Devin R Halleran, Laura Weaver, D Gregory Bates, Alessandra C Gasior, Tassiana Maloof, Erin J Hoover, Jordan Jaggers, Renae Gagnon, Christina C Ching, Daniel Dajusta, Venkata R Jayanthi, Marc A Levitt, Richard J Wood
BACKGROUND AND AIM: The sacral ratio (SR) is a well-established tool to quantify sacral development in patients with anorectal malformations (ARM) and can be used as a predictor of fecal continence. We hypothesized that a lower SR correlated with the presence of urologic and renal malformations. METHODS: We retrospectively reviewed the medical records of patients with ARM treated at our center from 2014 to 2016. We measured the lateral SR as a marker for sacral development and assessed the spine for the presence of tethered cord (TC)...
March 23, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29671672/pathophysiological-effect-of-bladder-outlet-obstruction-on-the-urothelium
#6
Grzegorz Niemczyk, Katarzyna Czarzasta, Piotr Radziszewski, Paweł Włodarski, Agnieszka Cudnoch-Jędrzejewska
Bladder outlet obstruction (BOO) and associated lower urinary tract symptoms are major urological issues that significantly affect patient's quality of life and may lead to severe complications. The prevalence of both is increasing each year, raising the burden to health system. Therefore, casual and symptomatic treatment should be of great importance. However, management of symptoms is often difficult as their pathophysiology is multifactorial and not well elucidated. Recently urothelium has gathered much attention as one of the potential causal agents...
April 19, 2018: Ultrastructural Pathology
https://www.readbyqxmd.com/read/29667065/single-site-laparoscopy-and-robotic-surgery-in-pediatric-urology
#7
REVIEW
Diana K Bowen, Jason P Van Batavia, Arun K Srinivasan
PURPOSE OF REVIEW: In this review, we summarize research that has evaluated the role of laparoendoscopic single-site (LESS) and robotic surgery in pediatric urology, highlighting new and/or controversial ideas. RECENT FINDINGS: The newest research developments over the last several years are studies that address generalizability of these techniques, ideal patient factors, extrapolation to more complex surgeries, and comparative studies to more traditional techniques to define the associated costs and benefits, as well as patient-centered outcomes...
April 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29666837/cancer-telomeres-and-white-crows
#8
REVIEW
Alan K Meeker
This mini-review article discusses past and present prostate-focused research on telomere and telomerase biology conducted at Johns Hopkins, through the eyes of a Donald S Coffey trainee. Included are past discoveries of abnormalities in telomere biology in the context of prostate cancer and its pre-malignant precursor prostatic intraepithelial neoplasia (PIN); the finding that telomerase activity is androgen-regulated in the prostate, and the potential role of telomerase in prostate epithelial stem cells. Also reviewed are more recent results showing that in situ telomere length measurements in patient tissue specimens may have utility in risk assessment and as a prognostic biomarker...
2018: American Journal of Clinical and Experimental Urology
https://www.readbyqxmd.com/read/29666835/aptamers-and-apple-pies-a-mini-review-of-psma-aptamers-and-lessons-from-donald-s-coffey
#9
REVIEW
Shawn E Lupold
This mini-review article is part of a special issue dedicated to Donald S. Coffey, a pioneer translational research scientist, exemplary mentor, and leader in urologic and urologic oncology research. This article first briefly reflects on life and scientific lessons from Don Coffey. It then reviews the development of two prostate cancer targeting RNA aptamers, xPSM-A9 and xPSM-A10, through in vitro selection for aptamers that bind to the extracellular domain of the Prostate Specific Membrane Antigen (PSMA)...
2018: American Journal of Clinical and Experimental Urology
https://www.readbyqxmd.com/read/29666747/symphysis-pubis-osteomyelitis-an-uncommon-complication-after-robotic-assisted-radical-prostatectomy-case-description-with-literature-review
#10
Jad A Degheili, Mazen M Mansour, Rami W Nasr
Prostate cancer is the most common solid cancer among American men. Although there are various modalities for treatment, including radical prostatectomy among many others, the former is, nevertheless, not without any accompanied complications. Other than the well-known surgical complications such as erectile dysfunction, urinary incontinence, and voiding dysfunction, osteomyelitis of the symphysis pubis is not a well-understood complication, with various hypotheses explaining its pathogenesis. Although osteomyelitis of the pubis symphysis has been reported after endoscopic urological procedures such as transurethral resection of the prostate, it has rarely been reported after robotic surgeries...
2018: Case Reports in Urology
https://www.readbyqxmd.com/read/29662543/optical-improvements-in-the-diagnosis-of-bladder-cancer-implications-for-clinical-practice
#11
REVIEW
Tina Schubert, Steffen Rausch, Omar Fahmy, Georgios Gakis, Arnulf Stenzl
Background: For over 100 years white-light cystoscopy has remained the gold-standard technique for the detection of bladder cancer (BCa). Some limitations in the detection of flat lesions (CIS), the differentiation between inflammation and malignancy, the inaccurate determination of the tumor margin status as well as the tumor depth, have led to a variety of technological improvements. The aim of this review is to evaluate the impact of these improvements in the diagnosis of BCa and their effectiveness in clinical practice...
November 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/29662542/meta-analysis-of-studies-comparing-oncologic-outcomes-of-radical-prostatectomy-and-brachytherapy-for-localized-prostate-cancer
#12
Gabriele Cozzi, Gennaro Musi, Roberto Bianchi, Danilo Bottero, Antonio Brescia, Antonio Cioffi, Giovanni Cordima, Maurizio Delor, Ettore Di Trapani, Matteo Ferro, Deliu Victor Matei, Andrea Russo, Francesco Alessandro Mistretta, Ottavio De Cobelli
Background: The aim of this study was to compare oncologic outcomes of radical prostatectomy (RP) with brachytherapy (BT). Methods: A literature review was conducted according to the 'Preferred reporting items for systematic reviews and meta-analyses' (PRISMA) statement. We included studies reporting comparative oncologic outcomes of RP versus BT for localized prostate cancer (PCa). From each comparative study, we extracted the study design, the number and features of the included patients, and the oncologic outcomes expressed as all-cause mortality (ACM), PCa-specific mortality (PCSM) or, when the former were unavailable, as biochemical recurrence (BCR)...
November 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/29661588/impact-of-metabolic-diseases-drugs-and-dietary-factors-on-prostate-cancer-risk-recurrence-and-survival-a-systematic-review-by-the-european-association-of-urology-section-of-oncological-urology
#13
REVIEW
Riccardo Campi, Sabine D Brookman-May, Jose Daniel Subiela Henríquez, Bülent Akdoğan, Maurizio Brausi, Tobias Klatte, Johan F Langenhuijsen, Estefania Linares-Espinos, Martin Marszalek, Morgan Roupret, Christian G Stief, Alessandro Volpe, Andrea Minervini, Oscar Rodriguez-Faba
CONTEXT: To date, established risk factors for prostate cancer (PCa) are limited to age, race, family history, and certain genetic polymorphisms. Despite great research efforts, available evidence on potentially modifiable risk factors is conflicting. Moreover, most studies on PCa risk factors did not consider the impact of prostate-specific antigen (PSA) testing on PCa diagnosis. OBJECTIVE: To provide a detailed overview of the latest evidence on the role of metabolic diseases, drugs, and dietary factors for risk of PCa incidence, recurrence, and survival in men exposed to PSA testing...
April 13, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29658681/laparoscopic-radical-prostatectomy-in-2018-20-years-of-worldwide-experiences-experimentations-researches-and-refinements
#14
Aldo Brassetti, Renaud Bollens
INTRODUCTION: After the first feasibility report in 1997, a growing interest has risen in the urologic community for laparoscopic radical prostatectomy (LRP) and several authors have contributed to the evolution of the technique. We attempt a review of the available evidences and provide a broad framework of different technical refinements considering their impact on pentafecta. EVIDENCE ACQUISITION: The PubMed/Medline database was searched. Duplicates and "Expert opinion" papers were removed...
April 13, 2018: Minerva Chirurgica
https://www.readbyqxmd.com/read/29658322/clinical-effectiveness-and-versatility-of-a-sealing-hemostatic-patch-hemopatch-in-multiple-surgical-specialties
#15
Kevin M Lewis, Shelly Ikeme, Tolu Olubunmi, Carl Erik Kuntze
Intraoperative surgical sealants and hemostatic agents have been shown to reduce postoperative complications, transfusions and hospital resource utilization. Despite availability of these agents, the incidence and burden of bleeding remains high and surgeons' requirements for hemostatic control continue to evolve. A burgeoning class of hemostatic agents are hemostatic patches, which offer package-to-patient readiness and direct application. In addition, hemostatic patches may provide tissue sealing capabilities...
April 16, 2018: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29653162/inconsistency-in-the-definition-of-urinary-tract-infection-after-intravesical-botulinum-toxin-a-injection-a-systematic-review
#16
Andrew W Stamm, Sarah A Adelstein, Andrew Chen, Alvaro Lucioni, Kathleen C Kobashi, Una J Lee
PURPOSE: In order to more accurately examine the rate of urinary tract infection following onabotulinumtoxinA injection of the bladder, we systematically reviewed the literature for definitions of urinary tract infection utilized in series that reported on onabotulinumtoxinA injections and assessed them for consistency with guideline statements defining urinary tract infections. MATERIALS AND METHODS: A systematic review of the literature was performed via query using MEDLINE and EMBASE...
April 10, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29650821/-continuation-of-axitinib-for-advanced-renal-cell-carcinoma-by-the-application-of-homecare-urology-a-case-report-and-literature-review
#17
Satoshi Yazawa, Yuji Kato, Jin Nakahara, Toshio Miyata, Mototsugu Oya
A 56-year-old man with advanced RCC and a past medical history of type 2 diabetes underwent a radical left nephrectomy following a histological diagnosis of papillary RCC, G2, INF b, pT3, V1 in 1999. In 2008, sorafenib was started to treat multiple pulmonary metastases of RCC. In 2011, sorafenib was switched to sunitinib when radiologic progression was observed. In 2014, sunitinib was switched to axitinib when further radiologic progression was observed. In 2015, the patient was referred to Yazawa clinic for homecare urology when hospital visits became difficult due to cancer pain and bilateral lower-extremity muscle weakness...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650457/-non-palpable-testicular-tumors-in-adults-a-management-based-on-imaging-issue-from-the-french-urologic-association-genital-cancer-committee-s-edit
#18
L Rocher, L Feretti, P Camparo, P H Savoie, N Morel-Journel, T Murez, P Sebe, A Flechon, A Méjean, X Durand
BACKGROUND: Help in management of non-palpable testicular tumors. French Urologic Association Genital cancer committee's Edit. OBJECTIVES: To review their characterization at imaging findings of non-palpable testicular tumors. DOCUMENTARY SOURCES: Literature review (PubMed, Medline) of urological and radiological studies dealing with testicular tumors using keywords: non-palpable/incidental testicular tumors; color Doppler ultrasound; US elastography; magnetic resonance imaging; contrast enhanced sonography; partial surgery...
April 9, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29649079/in-search-of-mobile-applications-for-urogynecology-providers
#19
Shannon L Wallace, Shailja Mehta, Sara Farag, Robert S Kelley, Katherine T Chen
INTRODUCTION: Thousands of medical applications (apps) are available for mobile devices. Finding accurate, health care provider-centered apps may be time consuming and frustrating for urogynecologists. The objective of this study was to identify and evaluate urogynecology (urogyn) apps using a modified APPLICATIONS scoring system. MATERIALS AND METHODS: Urogyn apps were identified from the Apple iTunes and Google Play Stores using the following 10 MeSH terms: urogynecology, incontinence, prolapse, urinary tract infection, pelvic surgery, fecal incontinence, defecation disorder, voiding disorder, urethral diverticulum, and fistula...
April 11, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29644169/testosterone-replacement-therapy-for-physician-assistants-and-nurse-practitioners
#20
REVIEW
Libert Ramos, Amir Shahreza Patel, Ranjith Ramasamy
Physician assistants (PA) and nurse practitioners have been moving toward specialty practices, like urology. With increased training and education, they manage more complex conditions independently. Whether they are the primary provider or the follow up to a specialist, physician extenders can play a vital role in managing patients undergoing testosterone therapy. Physician extenders should be able to understand the indications, risks and associated adverse effects of administering testosterone in order to proficiently take care of patients with low testosterone...
March 2018: Translational Andrology and Urology
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