keyword
MENU ▼
Read by QxMD icon Read
search

medaka

keyword
https://www.readbyqxmd.com/read/28800433/global-gene-expression-analysis-of-the-muscle-tissues-of-medaka-acclimated-to-low-and-high-environmental-temperatures
#1
Daisuke Ikeda, Hiroki Koyama, Nanami Mizusawa, Nobuhiro Kan-No, Engkong Tan, Shuichi Asakawa, Shugo Watabe
Medaka (Oryzias latipes) is a temperate eurythermal fish that is able to survive over a wide range of water temperatures ranging from near zero to over 30°C throughout the year; it maintains its normal physiological and biochemical processes through temperature acclimation. To determine the mechanisms involved in temperature acclimation of fish, the fast skeletal muscle tissues of medaka underwent global gene expression analysis using next-generation sequencing. Ten individuals were placed into two aquariums at 24°C...
August 2, 2017: Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics
https://www.readbyqxmd.com/read/28798535/effects-of-cadmium-exposure-on-medaka-oryzias-latipes-testes
#2
Ayano Hirako, Yuki Takeoka, Satoshi Furukawa, Akihiko Sugiyama
Adult male medaka (Oryzias latipes) were exposed to 10 ppm of cadmium for 96 h, and the testes were examined histopathologically. Numerous apoptotic cells were found in the spermatogonia and spermatocytes at 72 and 96 h after initiation of cadmium exposure, and the pyknotic index, TUNEL-positive rate, and cleaved caspase-3-positive rate in the spermatogonia and spermatocytes of the cadmium-treated group were higher compared with the control group. No significant difference between the control and cadmium-treated groups was found in the phospho-histone H3-positive rate in the spermatogonia and spermatocytes...
July 2017: Journal of Toxicologic Pathology
https://www.readbyqxmd.com/read/28792110/toxicity-of-extracts-from-municipal-wastewater-to-early-life-stages-of-japanese-medaka-oryzias-latipes-to-evaluate-removals-of-micropollutants-by-wastewater-treatment
#3
Nicholas Maya, Calvin Crispo, Victoria McFarland, Deniz Nasuhoglu, Siavash Isazadeh, Viviane Yargeau, Chris D Metcalfe
Treatment of municipal wastewater reduces the concentrations of some pharmaceuticals and personal care products, hormones and drugs of abuse. However, reduced concentrations of these micropollutants in wastewater may not correlate with reduced toxicity, as transformations of micropollutants and/or the formation of disinfection by-products may generate toxic compounds. In this study, we prepared extracts by solid phase extraction of samples collected from wastewater treatment plants (WWTPs) at various stages of treatment and tested these extracts for toxicity to early life stages of Japanese medaka (Oryzias latipes)...
August 9, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28782810/establishment-of-estrogen-receptor-1-esr1-knockout-medaka-esr1-is-dispensable-for-sexual-development-and-reproduction-in-medaka-oryzias-latipes
#4
Saki Tohyama, Yukiko Ogino, Anke Lange, Taijun Myosho, Tohru Kobayashi, Yu Hirano, Gen Yamada, Tomomi Sato, Norihisa Tatarazako, Charles R Tyler, Taisen Iguchi, Shinichi Miyagawa
Estrogens play fundamental roles in regulating reproductive activities and they act through estrogen receptor (ESR) in all vertebrates. Most vertebrates have two ESR subtypes (ESR1 and ESR2), whereas teleost fish have at least three (Esr1, Esr2a and Esr2b). Intricate functionalization has been suggested among the Esr subtypes, but to date, distinct roles of Esr have been characterized in only a limited number of species. Study of loss-of-function in animal models is a powerful tool for application to understanding vertebrate reproductive biology...
August 7, 2017: Development, Growth & Differentiation
https://www.readbyqxmd.com/read/28770388/parkinson-s-disease-pathogenesis-from-the-viewpoint-of-small-fish-models
#5
REVIEW
Hideaki Matsui, Ryosuke Takahashi
Parkinson's disease is a neurodegenerative disorder that involves movement discloses, degeneration of dopaminergic neurons, and presence of cytoplasmic inclusion bodies. Various animal models have been developed and small fish including zebrafish and medaka fish have recently been employed as a new model for Parkinson disease. In this review, we summarize fish models of Parkinson's disease mainly using our own findings and explain two major hypotheses of PD: lysosome dysfunction theory and mitochondrial dysfunction theory...
August 2, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28769117/species-specific-anaesthetics-for-fish-anaesthesia-and-euthanasia
#6
Gareth D Readman, Stewart F Owen, Toby G Knowles, Joanna C Murrell
There is a need to ensure that the care and welfare for fish maintained in the laboratory are to the highest standards. This extends to the use of anaesthetics for both scientific study, humane killing and euthanasia at end of life. An anaesthetic should not induce negative behaviours and fish should not seek to avoid the anaesthetic. Surprisingly little information is available to facilitate a humane choice of anaesthetic agent for fish despite over 100 years of use and the millions of fish currently held in thousands of laboratories worldwide...
August 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28767143/uva%C3%B9-induced-dna-damage-and-apoptosis-in-red-blood-cells-of-the-african-catfish-clarias-gariepinus
#7
Alaa El-Din Hamid Sayed
Ultraviolet-A light (UVA) -induced DNA damage and repair in red blood cells to investigate the sensitivity of African catfish to UVA exposure is reported. Fishes were irradiated with various doses of UVA light (15, 30, and 60 min/day for 3 days). Morphological and nuclear abnormalities in red blood cells were observed in the fish exposed to UVA compared with controls. Morphological alterations such as acanthocytes, crenated cells, swollen cells, teardrop-like cells, hemolyzed cells, and sickle cells were observed...
August 2, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28741124/characterization-of-a-low-density-lipoprotein-receptor-lrp13-in-chinese-tongue-sole-cynoglossus-semilaevis-and-medaka-oryzias-latipes
#8
Na Wang, Ruoqing Wang, Qiaomu Hu, Wenteng Xu, Ying Zhu, Fang Yan, Songlin Chen
As an important economic marine species cultured in China, Chinese tongue sole (Cynoglossus semilaevis) has interested us due to its sexual dimorphism and ZW/ZZ sex determination system. In a previous study, dmrt1 was identified as a dosage-dependent male-determining gene. In the present study, a female-specific expressed gene, cse0440, initially annotated as lrp1b-like, was identified from chromosome W of C. semilaevis. In view of the differences between cse0440 and lrp1b in terms of expression pattern, a phylogenetic analysis containing 85 LRP proteins was constructed and provided an evidence to re-annotate cse0440 as cseLRP13...
July 24, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28735237/effects-of-chronic-exposure-to-cefadroxil-and-cefradine-on-daphnia-magna-and-oryzias-latipes
#9
Bokyung Kim, Kyunghee Ji, Younglim Kho, Pan-Gyi Kim, Kyunghwa Park, Kyungtae Kim, Youngsuk Kim, Ki-Tae Kim, Kyungho Choi
Cefadroxil and cefradine have frequently been detected in surface waters, however toxicological studies in aquatic organisms have mostly been limited to acute lethal effects. In the present study, endocrine disruption caused by cefadroxil and cefradine, and its underlying mechanism were investigated by chronic exposure of Daphnia magna (21 d) and Oryzias latipes (120 d). In medaka fish, the effects on growth, mortality, and reproduction, as well as on the levels of hormones and genes related to the hypothalamic-pituitary-gonad (HPG) axis, were investigated after 120 d exposure...
July 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28728047/early-life-co-exposures-to-a-real-world-pah-mixture-and-hypoxia-result-in-later-life-and-next-generation-consequences-in-medaka-oryzias-latipes
#10
Jingli Mu, Melissa Chernick, Wu Dong, Richard T Di Giulio, David E Hinton
Acute effects of individual and complex mixtures of polycyclic aromatic hydrocarbons (PAHs) are well documented in vertebrate species. Hypoxia in fish reduces metabolic rate and reproduction. However, less is known about the later life consequences stemming from early-life exposure to PAHs or hypoxia, particularly their co-exposure. To address this, medaka (Oryzias latipes) embryos were exposed to a complex PAH mixture sediment extract from the Elizabeth River, VA (ERSE) at concentrations of 0.1, 0.5, or 1...
September 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28711606/ovarian-aromatase-loss-of-function-mutant-medaka-undergo-ovary-degeneration-and-partial-female-to-male-sex-reversal-after-puberty
#11
Masatoshi Nakamoto, Yasushi Shibata, Kaoru Ohno, Takeshi Usami, Yasuhiro Kamei, Yoshihito Taniguchi, Takeshi Todo, Takashi Sakamoto, Graham Young, Penny Swanson, Kiyoshi Naruse, Yoshitaka Nagahama
Although estrogens have been generally considered to play a critical role in ovarian differentiation in non-mammalian vertebrates, the specific functions of estrogens during ovarian differentiation remain unclear. We isolated two mutants with premature stops in the ovarian aromatase (cyp19a1) gene from an N-ethyl-N-nitrosourea-based gene-driven mutagenesis library of the medaka, Oryzias latipes. In XX mutants, gonads first differentiated into normal ovaries containing many ovarian follicles that failed to accumulate yolk...
July 12, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28708984/comparison-of-social-behavior-responses-of-japanese-medaka-oryzias-latipes-to-lethal-and-sublethal-chlorpyrifos-concentrations-at-different-exposure-times
#12
Fatma Khalil, Xuchun Qiu, Ik Joon Kang, Ismail Abo-Ghanema, Yohei Shimasaki, Yuji Oshima
Chlorpyrifos (CPF) is one of the most widely used insecticides and has been found in both urban and rural water bodies. In this study, we studied variations in the social behavioral patterns, swimming behavior, and brain acetylcholinesterase (AChE) activity of Japanese medaka exposed to lethal (0.12mg/L) and sublethal (0.012mg/L) concentrations of CPF after different exposure times. Group behavior performance (schooling, shoaling, and solitary) was determined on day 4 of lethal exposure and on days 4, 8, and 12 of sublethal exposure...
July 11, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28707405/generation-of-biallelic-f0-mutants-in-medaka-using-the-crispr-cas9-system
#13
Rie Sawamura, Natsumi Osafune, Takahiro Murakami, Fumiya Furukawa, Takeshi Kitano
Several animal models generated by genome editing methods develop somatic mosaic mutations including wild-type genome sequence in F0 generation because it is difficult to use editing tools at the one-cell stage. Producing complete knockout animals quickly is a great advantage in determining the function of target genes. This study investigated the generation of F0 knockout medaka using the CRISPR/Cas9 system. To determine whether this editing system induced mutations in the medaka genome at the one-cell stage, recombinant Cas9 protein, tracrRNA and crRNA for dead end (dnd), which is essential for germ cell development, were injected into one-cell stage embryos of olvas-DsRedExpress transgenic medaka...
July 14, 2017: Genes to Cells: Devoted to Molecular & Cellular Mechanisms
https://www.readbyqxmd.com/read/28698478/antifungal-and-ichthyotoxic-sesquiterpenoids-from-santalum-album-heartwood
#14
Tae Hoon Kim, Tsutomu Hatano, Keinosuke Okamoto, Takashi Yoshida, Hiroshi Kanzaki, Michiko Arita, Hideyuki Ito
In our continuing study on a survey of biologically active natural products from heartwood of Santalum album (Southwest Indian origin), we newly found potent fish toxic activity of an n-hexane soluble extract upon primary screening using killifish (medaka) and characterized α-santalol and β-santalol as the active components. The toxicity (median tolerance limit (TLm) after 24 h at 1.9 ppm) of α-santalol was comparable with that of a positive control, inulavosin (TLm after 24 h at 1.3 ppm). These fish toxic compounds including inulavosin were also found to show a significant antifungal effect against a dermatophytic fungus, Trichophyton rubrum...
July 8, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28698048/identification-and-functional-evaluation-of-two-stat3-variants-in-grass-carp-implication-for-the-existence-of-specific-alternative-splicing-of-stat3-gene-in-teleost
#15
Linyong Du, Hong Zhou, Lei Qin, He Wei, Anying Zhang, Kun Yang, Xinyan Wang
A STAT family member, STAT3, becomes activated as a DNA binding protein in response to cytokines and growth factors. In teleost, STAT3 cDNA has been cloned and identified in a few species, but only a single STAT3 transcript is revealed in these studies. In the present study, two variants of STAT3 gene generated by alternative splicing were isolated from grass carp and nominated as STAT3α1 and STAT3α2 based on the homology with their mammalian orthologs. In particular, the homologs of STAT3α1/2 were also found in various fish species, including zebrafish, takifugu, tilapia, medaka and goldfish...
July 8, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/28693720/individual-recognition-and-the-face-inversion-effect-in-medaka-fish-oryzias-latipes
#16
Mu-Yun Wang, Hideaki Takeuchi
Individual recognition (IR) is essential for maintaining various social interactions in a group, and face recognition is one of the most specialised cognitive abilities in IR. We used both a mating preference system and an electric shock conditioning experiment to test IR ability in medaka, and found that signals near the face are important. Medaka required more time to discriminate vertically inverted faces, but not horizontally shifted faces or inverted non-face objects. The ability may be comparable to the classic 'face inversion effect' in humans and some other mammals...
July 11, 2017: ELife
https://www.readbyqxmd.com/read/28677658/abscopal-activation-of-microglia-in-embryonic-fish-brain-following-targeted-irradiation-with-heavy-ion-microbeam
#17
Takako Yasuda, Miyuki Kamahori, Kento Nagata, Tomomi Watanabe-Asaka, Michiyo Suzuki, Tomoo Funayama, Hiroshi Mitani, Shoji Oda
Microglia remove apoptotic cells by phagocytosis when the central nervous system is injured in vertebrates. Ionizing irradiation (IR) induces apoptosis and microglial activation in embryonic midbrain of medaka (Oryzias latipes), where apolipoprotein E (ApoE) is upregulated in the later phase of activation of microglia In this study, we found that another microglial marker, l-plastin (lymphocyte cytosolic protein 1), was upregulated at the initial phase of the IR-induced phagocytosis when activated microglia changed their morphology and increased motility to migrate...
July 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28666956/coordination-of-cellular-differentiation-polarity-mitosis-and-meiosis-new-findings-from-early-vertebrate-oogenesis
#18
REVIEW
Yaniv M Elkouby, Mary C Mullins
A mechanistic dissection of early oocyte differentiation in vertebrates is key to advancing our knowledge of germline development, reproductive biology, the regulation of meiosis, and all of their associated disorders. Recent advances in the field include breakthroughs in the identification of germline stem cells in Medaka, in the cellular architecture of the germline cyst in mice, in a mechanistic dissection of chromosomal pairing and bouquet formation in meiosis in mice, in tracing oocyte symmetry breaking to the chromosomal bouquet of meiosis in zebrafish, and in the biology of the Balbiani body, a universal oocyte granule...
June 28, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28662518/effects-of-n-nitrosodiethylamine-a-potent-carcinogen-on-sexual-development-gametogenesis-and-oocyte-maturation
#19
Reshma Nair U, Anju C Victor, Vinod Paul, Bindhu Paul-Prasanth
N-Nitrosodiethylamine (DEN), a well-known hepatocarcinogen, is found in certain food products as such or as a metabolic byproduct. This study investigated the effects of DEN on sexual development, gametogenesis, and oocyte maturation in Japanese medaka (Oryzias latipes). DEN reduced the germ cell number dose-dependently during early stages of sexual differentiation in XX larvae, resulting in underdeveloped ovaries in adulthood at low doses. This effect was sex-specific as no such changes were seen in XY larvae...
2017: Sexual Development: Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation
https://www.readbyqxmd.com/read/28661683/identification-of-chemicals-that-cause-oxidative-stress-in-oil-sands-process-affected-water
#20
Jianxian Sun, Hui Peng, Hattan A Alharbi, Paul D Jones, John P Giesy, Steve B Wiseman
Oil sands process-affected water (OSPW) has been reported to cause oxidative stress in organisms, yet the causative agents remain unknown. In this study, a high-throughput in vitro Nrf2 reporter system was used, to determine chemicals in OSPW that cause oxidative stress. Five fractions, with increasing polarity, of the dissolved organic phase of OSPW were generated by use of solid phase extraction cartridges. The greatest response of Nrf2 was elicited by F2 (2.7 ± 0.1-fold), consistent with greater hydroperoxidation of lipids in embryos of Japanese medaka (Oryzias latipes) exposed to F2...
July 17, 2017: Environmental Science & Technology
keyword
keyword
2913
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"