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https://www.readbyqxmd.com/read/27915345/long-term-follow-up-of-patients-with-spasmodic-dysphonia-and-improved-voice-despite-discontinuation-of-treatment
#1
Ahmed Geneid, Per-Åke Lindestad, Svante Granqvist, Riitta Möller, Maria Södersten
OBJECTIVE: To evaluate voice function in patients with adductor spasmodic dysphonia (AdSD) who discontinued botulinum toxin (BTX) treatment because they felt that their voice had improved sufficiently. PATIENTS AND METHODS: Twenty-eight patients quit treatment in 2004, of whom 20 fulfilled the inclusion criteria for the study, with 3 subsequently excluded because of return of symptoms, leaving 17 patients (11 males, 6 females) included in this follow-up study. A questionnaire concerning current voice function and the Voice Handicap Index were completed...
December 3, 2016: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/27915336/effects-of-nasal-obstruction-due-to-nasal-polyposis-on-nasal-resonance-and-voice-perception
#2
Fatih Arslan, Bahtiyar Polat, Abdullah Durmaz, Hakan Birkent
OBJECTIVE: The aim of this study was to use subjective and objective methods to investigate the effects of total or nearly total nasal obstruction due to nasal polyposis on nasal resonance and voice perception. PATIENTS AND METHODS: A total of 63 nasal polyposis patients (53 men and 10 women), aged between 19 and 72 years (mean age 37.01 ± 13.70), were included in the study. The severity of the nasal obstruction was assessed using a visual analog scale. Nasal resonance and voice perception were evaluated subjectively by the voice handicap index (VHI)-10 questionnaire and objectively by computerized analysis (nasometry) before and after treatment of patients with nasal polyposis...
December 3, 2016: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/27915259/-standing-outside-the-junkie-door-service-users-experiences-of-using-community-pharmacies-to-access-treatment-for-opioid-dependency
#3
Andrew Radley, Karen Melville, Phyllis Easton, Brian Williams, John F Dillon
AIM: To explore experiences of service users attending a community pharmacy to receive opiate replacement therapy (ORT). METHOD: Qualitative study involving seven focus groups undertaken within care centres and prison educational centre in Tayside, Scotland using 41 participants. Thematic analysis undertaken of experiences of different groups of service users and carers. RESULTS: Participants described the social context surrounding attendance at community pharmacies...
December 2, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/27913092/evaluation-of-phonatory-behavior-and-voice-quality-in-patients-with-multiple-sclerosis-treated-with-deep-brain-stimulation
#4
Manfred Pützer, Wolfgang Wokurek, Jean Richard Moringlane
OBJECTIVES: The effect of deep brain stimulation (DBS) on phonatory behavior and voice quality in eight patients with multiple sclerosis (MS) was examined instrumentally and perceptually. The acoustic signals of vowel productions obtained from patients (produced with and without stimulation) and from a group of 16 healthy control speakers were analyzed to prove statistically the changes of phonatory behavior and voice quality. STUDY DESIGN: This is a randomized study...
November 30, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27898173/an-update-on-larynx-cancer
#5
REVIEW
Conor E Steuer, Mark El-Deiry, Jason R Parks, Kristin A Higgins, Nabil F Saba
Answer questions and earn CME/CNE Laryngeal cancer remains one of the most common tumors of the respiratory tract. Fortunately, significant advancements have been made over the past decade in the treatment of laryngeal cancer. Although surgery has been the historical mainstay for localized disease and still is an integral part of treatment, nonsurgical options like radiation and systemic therapy have emerged as viable options. In addition, in the metastatic setting, novel agents are showing promise for this patient population...
November 29, 2016: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/27893858/reversing-age-related-changes-of-the-laryngeal-muscles-by-chronic-electrostimulation-of-the-recurrent-laryngeal-nerve
#6
Michael Karbiener, Jonathan C Jarvis, Justin D Perkins, Hermann Lanmüller, Martin Schmoll, Hanna S Rode, Claus Gerstenberger, Markus Gugatschka
Age related atrophy of the laryngeal muscles -mainly the thyroarytenoid muscle (TAM)- leads to a glottal gap and consequently to a hoarse and dysphonic voice that significantly affects quality of life. The aim of our study was to reverse this atrophy by inducing muscular hypertrophy by unilateral functional electrical stimulation (FES) of the recurrent laryngeal nerve (RLN) in a large animal model using aged sheep (n = 5). Suitable stimulation parameters were determined by fatiguing experiments of the thyroarytenoid muscle in an acute trial...
2016: PloS One
https://www.readbyqxmd.com/read/27889029/patient-perspective-and-personal-journey-of-treating-a-rare-cancer
#7
REVIEW
Michele Longabaugh
I was diagnosed with rare anal cancer. As overwhelming as the diagnosis was, it was complicated by limited treatment infrastructure and clinical research, side-effect management, and lack of awareness and support organizations. Anal cancer encompasses so much more than receiving prescribed treatment and focusing on recovery. It requires patients to become experts on their disease, its treatment, and side effects. Even more challenging is finding support and advocacy. My experience has been difficult, complex, and arduous...
January 2017: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/27887811/using-the-borg-cr10-physical-exertion-scale-to-measure-patient-perceived-vocal-effort-pre-and-post-treatment
#8
Eva van Leer, Miriam van Mersbergen
OBJECTIVES: Reduction of vocal effort is a therapeutic goal in resonant voice therapy and in the treatment of a variety of voice disorders. The Borg CR10 is a perceived effort scale that is widely accepted across a wide variety of disciplines. The purpose of the present study was to examine (1) the utility of an anchored, adapted Borg CR10 in observing treatment-related vocal effort reduction and (2) the convergent validity of the Borg CR10 in its relation to Voice Handicap Index (VHI) item 14...
November 22, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27882709/technical-note-using-a-tracheal-stent-for-conservative-management-of-speaking-valve-associated-tracheo-oesophageal-fistula
#9
M Cunnane, S Patil, R Sothinathan, D Walker, M Gaulton, L Pitkin
Surgical voice rehabilitation is an essential dimension of treatment following total laryngectomy. The gold standard is tracheo-oesophageal puncture and speaking valve placement. Whilst offering excellent phonation in many patients, there is a well-documented risk of valve associated fistula formation, the incidence of which varies from 1 to 21% (1) . Risk factors for delayed valve associated tracheo-oesophageal fistula include post chemo-radiotherapy (salvage laryngectomy), oesophageal stricture, persistent fungal infection and poor patient compliance in managing their speaking valve(2) ...
November 24, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27882558/effects-of-voice-sparing-cricotracheal-resection-on-phonation-in-women
#10
Kristine Tanner, Christopher Dromey, Mark L Berardi, Lisa M Mattei, Jenny L Pierce, Jonathan J Wisco, Eric J Hunter, Marshall E Smith
INTRODUCTION: Individuals with idiopathic subglottic stenosis (SGS) are at risk for voice disorders prior to and following surgical management. This study examined the nature and severity of voice disorders in patients with SGS before and after a revised cricotracheal resection (CTR) procedure designed to minimize adverse effects on voice function. METHOD: Eleven women with idiopathic SGS provided presurgical and postsurgical audio recordings. Voice Handicap Index (VHI) scores were also collected...
November 24, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27877106/the-language-tone-and-prosody-of-emotions-neural-substrates-and-dynamics-of-spoken-word-emotion-perception
#11
REVIEW
Einat Liebenthal, David A Silbersweig, Emily Stern
Rapid assessment of emotions is important for detecting and prioritizing salient input. Emotions are conveyed in spoken words via verbal and non-verbal channels that are mutually informative and unveil in parallel over time, but the neural dynamics and interactions of these processes are not well understood. In this paper, we review the literature on emotion perception in faces, written words, and voices, as a basis for understanding the functional organization of emotion perception in spoken words. The characteristics of visual and auditory routes to the amygdala-a subcortical center for emotion perception-are compared across these stimulus classes in terms of neural dynamics, hemispheric lateralization, and functionality...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27876742/-on-the-problem-of-voice-rehabilitation-in-the-case-of-unilateral-vocal-fold-paresis
#12
V V Shilenkova
BACKGROUND: Unilateral vocal fold paresis (UVFP) significantly deteriorates the patient's quality of life. The leading role in the rehabilitation of the patients presenting with UVFP belongs to stimulation therapy which consists in the activation of muscle re-innervation of the larynx and the compensatory mechanisms allowing to achieve the most complete closure of the vocal folds during phonation. AIM: The objective of the present study was the optimization of the conservative treatment of patients with UVFP...
2016: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/27869566/gastrointestinal-comorbidities-which-complicate-the-treatment-of-anorexia-nervosa
#13
Margherita Mascolo, Bashir Geer, Joshua Feuerstein, Philip S Mehler
Patients with anorexia nervosa often voice a multitude of symptoms in regards to their gastrointestinal tract. These complaints can complicate the treatment of their eating disorder as they distract attention from the important goal of weight restoration. Moreover, the restricting of certain food groups also makes the task of weight restoration substantially more difficult, or may result in binging. Therefore a working knowledge of common gastrointestinal comorbidities, such as celiac disease, irritable bowel syndrome, inflammatory bowel disease, and gastroparesis, is useful when treating a patient who has anorexia nervosa...
November 21, 2016: Eating Disorders
https://www.readbyqxmd.com/read/27866691/vocal-parameters-and-self-perception-in-individuals-with-adductor-spasmodic-dysphonia
#14
Gleidy Vannesa E Rojas, Hilton Ricz, Vitor Tumas, Guilherme R Rodrigues, Patrícia Toscano, Lílian Aguiar-Ricz
OBJECTIVE: The study aimed to compare and correlate perceptual-auditory analysis of vocal parameters and self-perception in individuals with adductor spasmodic dysphonia before and after the application of botulinum toxin. STUDY DESIGN: This is a prospective cohort study. METHODS: Sixteen individuals with a diagnosis of adductor spasmodic dysphonia were submitted to the application of botulinum toxin in the thyroarytenoid muscle, to the recording of a voice signal, and to the Voice Handicap Index (VHI) questionnaire before the application and at two time points after application...
November 17, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27863807/head-to-head-comparison-of-certolizumab-pegol-versus-adalimumab-in-rheumatoid-arthritis-2-year-efficacy-and-safety-results-from-the-randomised-exxelerate-study
#15
Josef S Smolen, Gerd-Rüdiger Burmester, Bernard Combe, Jeffrey R Curtis, Stephen Hall, Boulos Haraoui, Ronald van Vollenhoven, Christopher Cioffi, Cécile Ecoffet, Leon Gervitz, Lucian Ionescu, Luke Peterson, Roy Fleischmann
BACKGROUND: To date, head-to-head trials comparing the efficacy and safety of biological disease-modifying antirheumatic drugs within the same class, including TNF inhibitors, in patients with active rheumatoid arthritis despite methotrexate therapy are lacking. We aimed to compare the efficacy and safety of two different TNF inhibitors and to assess the efficacy and safety of switching to the other TNF inhibitor without a washout period after insufficient primary response to the first TNF inhibitor at week 12...
November 11, 2016: Lancet
https://www.readbyqxmd.com/read/27863745/a-systematic-review-of-voice-therapy-what-effectiveness-really-implies
#16
REVIEW
Maude Desjardins, Lucinda Halstead, Melissa Cooke, Heather Shaw Bonilha
INTRODUCTION: Behavioral voice therapy guided by a speech-language pathologist is recommended as the main treatment approach for many kinds of voice disorders. Encouraging evidence regard of good outcomes from voice therapy has been found in two previous reviews on broad patient populations. However, no definitive conclusion on the effectiveness of direct voice therapy can be drawn from these reviews due to limitations of the included studies. AIMS: To review recent literature on voice therapy; to provide clinicians with a list of evidence-based voice therapy techniques; to incorporate the therapy components in a physiologically based model; to assess the limitations and progress achieved in the recent research on voice therapy...
November 15, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27860101/on-a-learning-curve-for-shared-decision-making-interviews-with-clinicians-using-the-knee-osteoarthritis-option-grid
#17
Glyn Elwyn, Julie Rasmussen, Katharine Kinsey, Jill Firth, Katy Marrin, Adrian Edwards, Fiona Wood
RATIONAL: Tools used in clinical encounters to illustrate to patients the risks and benefits of treatment options have been shown to increase shared decision making. However, we do not have good information about how these tools are viewed by clinicians and how clinicians think patients would react to their use. OBJECTIVE: Our aim was to examine clinicians' views about the possible and actual use of tools designed to support patients and clinicians to collaborate and deliberate about treatment options, namely, Option Grid decision aids...
November 16, 2016: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/27859286/effects-of-electrical-stimulation-on-vocal-functions-in-patients-with-nasopharyngeal-carcinoma
#18
Thomas Law, Kathy Y-S Lee, Rita W-M Wong, Yeptain Leung, Peter K-M Ku, Eddy W-Y Wong, Hok-Nam Li, Louisa K-Y Ng, C Andrew van Hasselt, Michael C-F Tong
OBJECTIVES/HYPOTHESIS: This study aimed to evaluate the effects of neuromuscular electrical stimulation (NMES) on vocal functions in patients with nasopharyngeal carcinoma following radiation therapy. STUDY DESIGN: Prospective, randomized controlled trial. METHODS: One hundred forty newly treated NPC patients were recruited and randomized into NMES or traditional swallowing exercise (TE) group. Participants received intensive NMES or traditional swallowing therapy and were followed up until 12 months postrandomization...
November 12, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27856480/dysarthria-in-individuals-with-parkinson-s-disease-a-protocol-for-a-binational-cross-sectional-case-controlled-study-in-french-and-european-portuguese-fralusopark
#19
Serge Pinto, Rita Cardoso, Jasmin Sadat, Isabel Guimarães, Céline Mercier, Helena Santos, Cyril Atkinson-Clement, Joana Carvalho, Pauline Welby, Pedro Oliveira, Mariapaola D'Imperio, Sónia Frota, Alban Letanneux, Marina Vigario, Marisa Cruz, Isabel Pavão Martins, François Viallet, Joaquim J Ferreira
INTRODUCTION: Individuals with Parkinson's disease (PD) have to deal with several aspects of voice and speech decline and thus alteration of communication ability during the course of the disease. Among these communication impairments, 3 major challenges include: (1) dysarthria, consisting of orofacial motor dysfunction and dysprosody, which is linked to the neurodegenerative processes; (2) effects of the pharmacological treatment, which vary according to the disease stage; and (3) particular speech modifications that may be language-specific, that is, dependent on the language spoken by the patients...
November 17, 2016: BMJ Open
https://www.readbyqxmd.com/read/27845765/intranasal-oxytocin-enhances-connectivity-in-the-neural-circuitry-supporting-social-motivation-and-social-perception-in-children-with-autism
#20
Ilanit Gordon, Allison Jack, Charlotte M Pretzsch, Brent Vander Wyk, James F Leckman, Ruth Feldman, Kevin A Pelphrey
Oxytocin (OT) has become a focus in investigations of autism spectrum disorder (ASD). The social deficits that characterize ASD may relate to reduced connectivity between brain sites on the mesolimbic reward pathway (nucleus accumbens; amygdala) that receive OT projections and contribute to social motivation, and cortical sites involved in social perception. Using functional magnetic resonance imaging and a randomized, double blind, placebo-controlled crossover design, we show that OT administration in ASD increases activity in brain regions important for perceiving social-emotional information...
November 15, 2016: Scientific Reports
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