keyword
https://read.qxmd.com/read/36228840/hemodynamic-and-echocardiographic-predictors-of-mortality-in-pediatric-patients-on-venoarterial-extracorporeal-membrane-oxygenation-a-multicenter-investigation
#1
MULTICENTER STUDY
Rajesh Punn, Christine B Falkensammer, Joshua J Blinder, Carlen G Fifer, Thor Thorsson, Gregory Perens, Myke Federman, Punkaj Gupta, Thomas Best, Bhawna Arya, Titus Chan, Sara Sherman-Levine, Shea N Smith, David M Axelrod, Stephen J Roth, Theresa A Tacy
BACKGROUND: Venoarterial extracorporeal membrane oxygenation (ECMO) supports patients with advanced cardiac dysfunction; however, mortality occurs in a significant subset of patients. The authors performed a multicenter, prospective study to determine hemodynamic and echocardiographic predictors of mortality in children placed on ECMO for cardiac support. METHODS: Over 8 years, six heart centers prospectively assessed echocardiographic and hemodynamic variables on full and minimum ECMO flow...
February 2023: Journal of the American Society of Echocardiography
https://read.qxmd.com/read/32365284/an-international-survey-comparing-different-physician-models-for-health-care-delivery-to-critically-ill-children-with-heart-disease
#2
JOURNAL ARTICLE
Priya Bhaskar, Mallikarjuna Rettiganti, Efraim Sadot, Thomas Paul, Daniel Garros, Lorry R Frankel, Brian Reemtsen, Warwick Butt, Punkaj Gupta
OBJECTIVES: To explore relationships between the training background of cardiac critical care attending physicians and self-reported perceived strengths and weaknesses in their ability to provide clinical care. DESIGN: Cross-sectional observational survey sent worldwide to ~550 practicing cardiac ICU attending physicians. SETTING: Hospitals providing cardiac critical care. SUBJECTS: Practicing cardiac critical care physicians...
May 2020: Pediatric Critical Care Medicine
https://read.qxmd.com/read/31554949/factors-associated-with-motor-vehicle-related-eye-injuries-presenting-to-the-us-emergency-departments
#3
JOURNAL ARTICLE
Sunali Goyal, Mallikarjuna Rettiganti, Punkaj Gupta
OBJECTIVES: To evaluate risk factors associated with eye injuries related to motor vehicle accidents (MVA) using a multicentre national database from the US emergency departments. PATIENTS AND METHODS: A post hoc analysis from the Nationwide Emergency Department Sample database (2006-2013) was performed. Patients presenting to the emergency department (ED) with MVA-related trauma were included. We then evaluated patient- and centre-level risk factors associated with the presence of ocular trauma using a multivariable logistic regression model...
September 25, 2019: Eye
https://read.qxmd.com/read/30789090/characteristics-and-fate-of-abstracts-presented-at-american-academy-of-ophthalmology-meetings
#4
JOURNAL ARTICLE
Sunali Goyal, David A Kilgore, Samia F Nawaz, Mallikarjuna Rettiganti, Punkaj Gupta
PURPOSE: The purpose of this study is to evaluate the characteristics and publication outcomes of abstracts presented in American Academy of Ophthalmology (AAO) meetings. SUBJECT AND METHODS: Abstracts from AAO meetings for the years 2012 and 2013 were evaluated from the meeting archives. The study characteristics were recorded for each abstract. Each abstract was assessed for publication in a peer-reviewed scientific journal using three search engines (PubMed, Medline, and Google Scholar)...
2019: Seminars in Ophthalmology
https://read.qxmd.com/read/30342418/creation-of-an-empiric-tool-to-predict-ecmo-deployment-in-pediatric-respiratory-or-cardiac-failure
#5
JOURNAL ARTICLE
Punkaj Gupta, Jeffrey M Gossett, Danny Kofos, Mallikarjuna Rettiganti
PURPOSE: To create a real-time prediction tool to predict probability of ECMO deployment in children with cardiac or pulmonary failure. MATERIALS AND METHODS: Patients ≤18 years old admitted to an ICU that participated in the Virtual Pediatric Systems database (2009-2015) were included. Logistic regression models using adaptive lasso methodology were used to identify independent factors associated with ECMO use. RESULTS: A total of 538,202 ICU patients from 140 ICUs qualified for inclusion...
February 2019: Journal of Critical Care
https://read.qxmd.com/read/30222635/magnitude-and-pace-of-improvement-in-performance-of-hospitals-treating-mechanically-ventilated-children-in-the-united-states-analysis-from-two-national-databases
#6
JOURNAL ARTICLE
Punkaj Gupta, Jeffrey M Gossett, Mallikarjuna Rettiganti
OBJECTIVES: To use two national databases to quantify the pace and magnitude of improvement in hospital performance (as measured by mortality) across hospitals caring for critically ill children in the United States. DESIGN: We used empirical Bayes shrinkage estimators to obtain shrinkage estimators of observed/expected mortality ratios for each hospital assuming a Gamma Poisson posterior distribution. Revised mortality rates for each hospital were obtained from the shrunken incidence ratios...
December 2018: Critical Care Medicine
https://read.qxmd.com/read/30179621/characteristics-and-fate-of-pediatric-heart-disease-abstracts-presented-at-national-meetings
#7
JOURNAL ARTICLE
Pushpa Shivaram, Mallikarjuna Rettiganti, Paul M Seib, Punkaj Gupta
BACKGROUND: This study evaluated the characteristics and publication outcomes of pediatric heart disease abstracts presented in national meetings. METHODS: Three years of abstracts (2012-2014) were evaluated from five national meetings: Society of Thoracic Surgeons (STS), American Association of Thoracic Surgeons (AATS), American College of Cardiology (ACC), American Academy of Pediatrics (AAP), and American Heart Association (AHA). Each abstract was assessed for publication in a peer-reviewed scientific journal, time to publication, impact factor of the journal, and number of citations associated with the publication...
September 1, 2018: Annals of Thoracic Surgery
https://read.qxmd.com/read/30157739/incidence-of-immediate-extubation-after-pediatric-cardiac-surgery-and-predictors-for-reintubation
#8
JOURNAL ARTICLE
Takeshi Shinkawa, Xinyu Tang, Jeffrey M Gossett, Rahul Dasgupta, Michael L Schmitz, Punkaj Gupta, Michiaki Imamura
OBJECTIVES: The objectives were to assess the incidence of immediate tracheal extubation in the operating room after pediatric cardiac surgery and to investigate predictors for subsequent reintubation. METHODS: This is a single institutional retrospective study including all patients who had a cardiac operation with cardiopulmonary bypass from 2011 to 2016. Patients who required preoperative ventilator support, postoperative open chest, or mechanical support were excluded...
September 2018: World Journal for Pediatric & Congenital Heart Surgery
https://read.qxmd.com/read/30126659/reclassifying-by-highest-complexity-operation-rather-than-first-operation-influences-mortality-after-pediatric-heart-surgery
#9
MULTICENTER STUDY
Punkaj Gupta, Mallikarjuna Rettiganti, Takeshi Shinkawa, Jeffrey M Gossett, Nancy Brundage, Howard E Jeffries, Rebecca A Bertrandt
OBJECTIVE: To evaluate the effect on mortality of reclassifying patients undergoing pediatric heart reoperations of varying complexity by operation of highest complexity instead of by first operation. METHODS: Data from the Virtual Pediatric Systems Database on children aged < 18 years who underwent heart surgery (with or without cardiopulmonary bypass) were included (2009-2015). Only patients who underwent reoperations during the same hospitalization were included...
November 2018: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/29863647/the-quest-to-optimize-pediatric-interhospital-transport
#10
EDITORIAL
Punkaj Gupta, Mallikarjuna Rettiganti
No abstract text is available yet for this article.
June 2018: Pediatric Critical Care Medicine
https://read.qxmd.com/read/29727419/success-of-a-patient-and-family-centered-pediatric-specialty-care-model-for-management-of-chronic-respiratory-failure
#11
EDITORIAL
Punkaj Gupta, Mallikarjuna Rettiganti
No abstract text is available yet for this article.
May 2018: Pediatric Critical Care Medicine
https://read.qxmd.com/read/29440830/impact-of-intensive-care-unit-attending-physician-training-background-on-outcomes-in-children-undergoing-heart-operations
#12
JOURNAL ARTICLE
Priya Bhaskar, Mallikarjuna Rettiganti, Jeffrey M Gossett, Punkaj Gupta
BACKGROUND: The existing training pathways to become a pediatric cardiac intensivist are very variable with physicians coming from varied training backgrounds of pediatric critical care, pediatric cardiology, neonatology, or pediatric anesthesia. AIM: To evaluate the impact of cardiac Intensive Care Unit (ICU) attending physician training background on outcomes in children undergoing heart operations. SETTING AND DESIGN: Patients in the age group from 1 day to 18 years undergoing heart operation at a Pediatric Health Information System database participating hospital were included (2010-2015)...
January 2018: Annals of Pediatric Cardiology
https://read.qxmd.com/read/29360599/an-empirically-derived-pediatric-cardiac-inotrope-score-associated-with-pediatric-heart-surgery
#13
JOURNAL ARTICLE
Punkaj Gupta, Mallikarjuna Rettiganti, Andrew Wilcox, Mai-Anh Vuong-Dac, Jeffrey M Gossett, Michiaki Imamura, Avishek Chakraborty
We aimed to empirically derive an inotrope score to predict real-time outcomes using the doses of inotropes after pediatric cardiac surgery. The outcomes evaluated included in-hospital mortality, prolonged hospital length of stay, and composite poor outcome (mortality or prolonged hospital length of stay). The study population included patients <18 years of age undergoing heart operations (with or without cardiopulmonary bypass) of varying complexity. To create this novel pediatric cardiac inotrope score (PCIS), we collected the data on the highest doses of 4 commonly used inotropes (epinephrine, norepinephrine, dopamine, and milrinone) in the first 24 hours after heart operation...
2018: Seminars in Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/29102066/response-to-letter-is-magnet%C3%A2-recognition-associated-with-improved-outcomes-among-critically-ill-children-treated-at-freestanding-children-s-hospitals
#14
COMMENT
Mallikarjuna Rettiganti, Punkaj Gupta
No abstract text is available yet for this article.
February 2018: Journal of Critical Care
https://read.qxmd.com/read/28991830/development-and-validation-of-an-empiric-tool-to-predict-favorable-neurologic-outcomes-among-picu-patients
#15
JOURNAL ARTICLE
Punkaj Gupta, Mallikarjuna Rettiganti, Jeffrey M Gossett, Jennifer Daufeldt, Tom B Rice, Randall C Wetzel
OBJECTIVES: To create a novel tool to predict favorable neurologic outcomes during ICU stay among children with critical illness. DESIGN: Logistic regression models using adaptive lasso methodology were used to identify independent factors associated with favorable neurologic outcomes. A mixed effects logistic regression model was used to create the final prediction model including all predictors selected from the lasso model. Model validation was performed using a 10-fold internal cross-validation approach...
January 2018: Critical Care Medicine
https://read.qxmd.com/read/28941736/a-prognostic-tool-to-predict-outcomes-in-children-undergoing-the-norwood-operation
#16
JOURNAL ARTICLE
Punkaj Gupta, Avishek Chakraborty, Jeffrey M Gossett, Mallikarjuna Rettiganti
OBJECTIVES: To create and validate a prediction model to assess outcomes associated with the Norwood operation. METHODS: The public-use dataset from a multicenter, prospective, randomized single-ventricle reconstruction trial was used to create this novel prediction tool. A Bayesian lasso logistic regression model was used for variable selection. We used a hierarchical framework by representing discrete probability models with continuous latent variables that depended on the risk factors for a particular patient...
December 2017: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/28928608/intraocular-pressure-in-children-after-congenital-heart-surgery-a-single-center-study
#17
JOURNAL ARTICLE
Sunali Goyal, Paul H Phillips, Lamonda A Corder, Michael J Robertson, Xiomara Garcia, Michael L Schmitz, Punkaj Gupta
BACKGROUND: The impact of varied cardiac physiologies on intraocular pressure (IOP) among children undergoing heart operations is unknown. AIM: The aim of this study was to determine the IOP among children with varying cardiovascular physiologies and varying hemodynamics after their heart operation. SETTING AND DESIGN: This was a prospective, observational study. MATERIALS AND METHODS: Patients ≤18 years undergoing congenital heart surgery were included in this study...
September 2017: Annals of Pediatric Cardiology
https://read.qxmd.com/read/28917160/is-magnet%C3%A2-recognition-associated-with-improved-outcomes-among-critically-ill-children-treated-at-freestanding-children-s-hospitals
#18
JOURNAL ARTICLE
Mallikarjuna Rettiganti, Kavisha M Shah, Jeffrey M Gossett, Joshua A Daily, Paul M Seib, Punkaj Gupta
PURPOSE: With increasing emphasis on high-quality care, we designed this study to evaluate the relationship between Magnet® recognition and patient outcomes in pediatric critical care. MATERIALS AND METHODS: Post hoc analysis of data from an existing administrative national database. We used inverse probability of treatment weighting and multivariate models to compare outcomes between two study groups after adjusting for confounding variables. RESULTS: A total of 823,634 pediatric patients from 41 centers were included...
February 2018: Journal of Critical Care
https://read.qxmd.com/read/28696880/performance-of-pediatric-risk-of-mortality-score-among-critically-ill-children-with-heart-disease
#19
MULTICENTER STUDY
Rebecca A Russell, Mallikarjuna Rettiganti, Nancy Brundage, Howard E Jeffries, Punkaj Gupta
OBJECTIVE: To evaluate the performance of the Pediatric Risk of Mortality 3 (PRISM-3) score in critically ill children with heart disease. METHODS: Patients <18 years of age admitted with cardiac diagnoses (cardiac medical and cardiac surgical) to one of the participating pediatric intensive care units in the Virtual Pediatric Systems, LLC, database were included. Performance of PRISM-3 was evaluated with discrimination and calibration measures among both cardiac surgical and cardiac medical patients...
July 2017: World Journal for Pediatric & Congenital Heart Surgery
https://read.qxmd.com/read/28419060/relationship-of-hospital-costs-with-mortality-in-pediatric-critical-care-a-multi-institutional-analysis
#20
MULTICENTER STUDY
Punkaj Gupta, Mallikarjuna Rettiganti
OBJECTIVE: With increasing emphasis on high "value" care, we designed this study to evaluate the relationship between hospital costs and patient outcomes in pediatric critical care. DESIGN: Post hoc analysis of data from an existing administrative national database, Pediatric Health Information Systems. Multivariable mixed effects logistic regression models were fitted to evaluate association of hospital cost tertiles with odds of mortality after adjusting for patient and center characteristics...
June 2017: Pediatric Critical Care Medicine
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