keyword
https://read.qxmd.com/read/38536925/virtual-formalin-fixed-and-paraffin-embedded-staining-of-fresh-brain-tissue-via-stimulated-raman-cyclegan-model
#1
JOURNAL ARTICLE
Zhijie Liu, Lingchao Chen, Haixia Cheng, Jianpeng Ao, Ji Xiong, Xing Liu, Yaxin Chen, Ying Mao, Minbiao Ji
Intraoperative histology is essential for surgical guidance and decision-making. However, frozen-sectioned hematoxylin and eosin (H&E) staining suffers from degraded accuracy, whereas the gold-standard formalin-fixed and paraffin-embedded (FFPE) H&E is too lengthy for intraoperative use. Stimulated Raman scattering (SRS) microscopy has shown rapid histology of brain tissue with lipid/protein contrast but is challenging to yield images identical to nucleic acid-/protein-based FFPE stains interpretable to pathologists...
March 29, 2024: Science Advances
https://read.qxmd.com/read/38536892/subgraph-isomorphic-decision-tree-to-predict-radical-thermochemistry-with-bounded-uncertainty-estimation
#2
JOURNAL ARTICLE
Hao-Wei Pang, Xiaorui Dong, Matthew S Johnson, William H Green
Detailed chemical kinetic models offer valuable mechanistic insights into industrial applications. Automatic generation of reliable kinetic models requires fast and accurate radical thermochemistry estimation. Kineticists often prefer hydrogen bond increment (HBI) corrections from a closed-shell molecule to the corresponding radical for their interpretability, physical meaning, and facilitation of error cancellation as a relative quantity. Tree estimators, used due to limited data, currently rely on expert knowledge and manual construction, posing challenges in maintenance and improvement...
March 27, 2024: Journal of Physical Chemistry. A
https://read.qxmd.com/read/38536686/wdff-net-weighted-dual-branch-feature-fusion-network-for-polyp-segmentation-with-object-aware-attention-mechanism
#3
JOURNAL ARTICLE
Jie Cao, Xin Wang, Zhiwei Qu, Li Zhuo, Xiaoguang Li, Hui Zhang, Yang Yang, Wei Wei
Colon polyps in colonoscopy images exhibit significant differences in color, size, shape, appearance, and location, posing significant challenges to accurate polyp segmentation. In this paper, a Weighted Dual-branch Feature Fusion Network is proposed for Polyp Segmentation, named WDFF-Net, which adopts HarDNet68 as the backbone network. Firstly, a dual-branch feature fusion network architecture is constructed, which includes a shared feature extractor and two feature fusion branches, i.e. Progressive Feature Fusion (PFF) branch and Scale-aware Feature Fusion (SFF) branch...
March 27, 2024: IEEE Journal of Biomedical and Health Informatics
https://read.qxmd.com/read/38535739/physiological-responses-and-performance-during-an-integrated-high-intensity-interval-aerobic-and-power-training-protocol
#4
JOURNAL ARTICLE
Ilias Iason Psarras, Gregory C Bogdanis
This study compared the acute physiological responses and performance changes during an integrated high-intensity interval aerobic and power protocol. Sixteen moderately trained athletes (age: 20.1 ± 2.2 years, body height: 180.0 ± 6.5 cm, body mass: 75.7 ± 6.4 kg, VO2max : 55.8 ± 4.3 mL/kg/min) performed a 2 × 6 min interval training protocol with 2 min passive recovery between sets on two different occasions in random and counterbalanced order. Each 6 min set included repeated periods of 15 s exercise interspersed with 15 s passive rest...
March 7, 2024: Sports
https://read.qxmd.com/read/38535730/improvements-in-jump-height-speed-and-quality-of-life-through-an-8-week-strength-program-in-male-adolescents-soccer-players
#5
JOURNAL ARTICLE
Sara Díaz-Hidalgo, Antonio Ranchal-Sanchez, Jose Manuel Jurado-Castro
This study aimed to assess the enhancement of physical fitness and quality of life through an 8-week strength training program in male adolescent soccer players aged between 12 and 13 years. A lower body muscle group intervention was performed, with 17 players in the experimental group (EG) and 15 players in the control group (CG). The EG carried out soccer training complemented by specific strength work. Pre- and post- intervention assessments included body composition, jump height, speed with change of direction, maximum speed in 20 m, movement velocity in back-squat, perceived fatigue effort, academic performance, and quality of life...
February 23, 2024: Sports
https://read.qxmd.com/read/38535433/exploring-indicators-for-training-load-control-in-young-swimmers-the-role-of-inspiratory-spirometry-outcomes
#6
JOURNAL ARTICLE
Adrián Feria-Madueño, Nuno Batalha, Germán Monterrubio-Fernández, Jose A Parraca
One of the most important implications of technology in swimming is to control training loads. Lactate control, video-analysis of the technique or the assessment of specific actions, i.e., the vertical jump, have helped to provide load adaptation indicators in swimmers in recent decades. However, these indicators have led to a longer application time, due to their indirect procedure and the need to analyze each variable. The aim of this study was to analyze whether inspiratory spirometry values can serve as a training load control tool in swimmers...
March 18, 2024: Journal of Functional Morphology and Kinesiology
https://read.qxmd.com/read/38535430/effects-of-instability-neuromuscular-training-using-an-inertial-load-of-water-on-the-balance-ability-of-healthy-older-women-a-randomized-clinical-trial
#7
JOURNAL ARTICLE
Shuho Kang, Ilbong Park
The reflexive responses to resist external forces and maintain posture result from the coordination between the vestibular system, muscle, tendon, and joint proprioceptors, and vision. Aging deteriorates these crucial functions, increasing the risk of falls. This study aimed to verify whether a training program with water bags, an Instability Neuromuscular training (INT) using the inertial load of water, could positively impact balance ability and dynamic stability. This study was conducted with twenty-two healthy older women aged ≥ 65 (mean age: 74...
March 13, 2024: Journal of Functional Morphology and Kinesiology
https://read.qxmd.com/read/38534857/design-optimization-of-a-soft-robotic-rehabilitation-glove-based-on-finger-workspace-analysis
#8
JOURNAL ARTICLE
Yechan Lee, Hyung-Soon Park
The finger workspace is crucial for performing various grasping tasks. Thus, various soft rehabilitation gloves have been developed to assist individuals with paralyzed hands in activities of daily living (ADLs) or rehabilitation training. However, most soft robotic glove designs are insufficient to assist with various hand postures because most of them use an underactuated mechanism for design simplicity. Therefore, this paper presents a methodology for optimizing the design of a high-degree-of-freedom soft robotic glove while not increasing the design complexity...
March 13, 2024: Biomimetics
https://read.qxmd.com/read/38534542/seed-train-optimization-in-microcarrier-based-cell-culture-post-in-situ-cell-detachment-through-scale-down-hybrid-modeling
#9
JOURNAL ARTICLE
Atefeh Ebrahimian, Mona Schalk, Mark Dürkop, Michael Maurer, Rudolf Bliem, Harald Kühnel
Microcarrier-based cell culture is a commonly used method to facilitate the growth of anchorage-dependent cells like MA 104 for antigen manufacturing. However, conventionally, static cell culture is employed for cell propagation before seeding the production bioreactor with microcarriers (MCs). This study demonstrates the effective replacement of the conventional method by serial subculturing on MCs with in situ cell detachment under optimal conditions in closed culture units. This study proves that MA 104 can be subcultured at least five times on Cytodex 1 MC without the need for separating cells and MC after cell harvest...
March 9, 2024: Bioengineering
https://read.qxmd.com/read/38533062/effects-of-plyometric-training-on-skill-related-physical-fitness-in-badminton-players-a-systematic-review-and-meta-analysis
#10
JOURNAL ARTICLE
Nuannuan Deng, Kim Geok Soh, Borhannudin Bin Abdullah, Dandan Huang
Skill-related physical fitness significantly correlates with sports performance. Plyometric training (PT) is an effective method for improving physical fitness in athletes. However, its impact on skill-related physical fitness in badminton players remains uncertain. Therefore, this systematic review and meta-analysis aimed to evaluate the effectiveness of PT on skill-related physical fitness in badminton players. Five electronic databases (Web of Science, PubMed, SCOPUS, MEDLINE, and SPORTSDiscus) were searched until February 2024...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38532054/atp-releasing-channels-and-the-ameliorative-effects-of-high-intensity-interval-training-on-diabetic-heart-a-multifaceted-analysis
#11
JOURNAL ARTICLE
Siyavash Joukar, Mohammad Amin Rajizadeh, Mohammad Abbas Bejeshk, Samaneh Sadat Alavi, Fatemeh Bagheri, Mohammad Rami, Kayvan Khoramipour
Type 2 diabetes (T2D) can cause severe cardiac complications at functional, histologic and molecular levels. These pathological complications could be mediated by ATP-releasing channels such as Panx1 and ATP receptors, in particular P2X7. The aim of our study was to investigate the effect of high-intensity interval training (HIIT) on T2D-induced cardiac complications at the functional, histopathological and molecular levels, with a particular focus on ATP-releasing channels. 48 male Wistar rats at the age of 8 weeks were randomly allocated into four groups: control (Con), Diabetes (T2D), Training (TR), and Diabetes + Training (T2D + TR)...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531968/prismatic-adaptation-coupled-with-cognitive-training-as-novel-treatment-for-developmental-dyslexia-a-randomized-controlled-trial
#12
JOURNAL ARTICLE
Giulia Conte, Lauro Quadrana, Lilian Zotti, Agnese Di Garbo, Massimiliano Oliveri
Despite intense and costly treatments, developmental dyslexia (DD) often persists into adulthood. Several brain skills unrelated to speech sound processing (i.e., phonology), including the spatial distribution of visual attention, are abnormal in DD and may represent possible treatment targets. This study explores the efficacy in DD of rightward prismatic adaptation (rPA), a visuomotor adaptation technique that enables visuo-attentive recalibration through shifts in the visual field induced by prismatic goggles...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531890/highlighting-the-effects-of-high-intensity-interval-training-on-the-changes-associated-with-hypertrophy-apoptosis-and-histological-proteins-of-the-heart-of-old-rats-with-type-2-diabetes
#13
JOURNAL ARTICLE
Mohammad Rami, Amirhossein Ahmadi Hekmatikar, Samaneh Rahdar, Sayed Shafa Marashi, D Maryama Awang Daud
T2DM is known to cause disturbances in glucose homeostasis and negative changes in the heart muscle, while aging and diabetes are recognized risk factors for CVD. Given this, our study aims to investigate a method for controlling and managing CVDs induced by T2DM in elderly populations. To achieve this, we categorized 40 rats into 5 groups, including HAD (n = 8), HA (n = 8), AD (n = 8), AHT (n = 8), and ADT (n = 8). The exercise protocol consisted of eight weeks of HIIT (three sessions per week) performed at 90-95% of maximal speed...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38530543/viscoelastic-parameters-derived-from-multifrequency-mr-elastography-for-depicting-hepatic-fibrosis-and-inflammation-in-chronic-viral-hepatitis
#14
JOURNAL ARTICLE
Yikun Wang, Jiahao Zhou, Huimin Lin, Huafeng Wang, Ingolf Sack, Jing Guo, Fuhua Yan, Ruokun Li
OBJECTIVES: The capability of MR elastography (MRE) to differentiate fibrosis and inflammation, and to provide precise diagnoses is crucial, whereas the coexistence of fibrosis and inflammation may obscure the diagnostic accuracy. METHODS: In this retrospective study, from June 2020 to December 2022, chronic viral hepatitis patients who underwent multifrequency MRE (mMRE) were included in, and further divided into, training and validation cohorts. The hepatic viscoelastic parameters [shear wave speed (c) and loss angle (φ) of the complex shear modulus] were obtained from mMRE...
March 26, 2024: Insights Into Imaging
https://read.qxmd.com/read/38528438/implementing-a-ward-level-intervention-to-improve-nursing-handover-communication-with-a-focus-on-bedside-handover-a-qualitative-study
#15
JOURNAL ARTICLE
Laura J Chien, Diana Slade, Liza Goncharov, Joanne Taylor, Maria R Dahm, Bernadette Brady, Jake McMahon, Suzanne Eggins Raine, Anna Thornton
AIM: To improve the effectiveness of nursing clinical handover through a qualitative, tailored communication intervention. DESIGN: A multisite before and after intervention using qualitative ethnography combined with discourse analysis of nursing handover interactions. METHODS: We implemented a tailored ward-based intervention to redesign nursing handover practice with co-constructed recommendations for organisational and cultural change on seven wards across three affiliated metropolitan hospitals between February 2020 and November 2022...
March 25, 2024: Journal of Clinical Nursing
https://read.qxmd.com/read/38528306/pitsurgrt-real-time-localization-of-critical-anatomical-structures-in-endoscopic-pituitary-surgery
#16
JOURNAL ARTICLE
Zhehua Mao, Adrito Das, Mobarakol Islam, Danyal Z Khan, Simon C Williams, John G Hanrahan, Anouk Borg, Neil L Dorward, Matthew J Clarkson, Danail Stoyanov, Hani J Marcus, Sophia Bano
PURPOSE: Endoscopic pituitary surgery entails navigating through the nasal cavity and sphenoid sinus to access the sella using an endoscope. This procedure is intricate due to the proximity of crucial anatomical structures (e.g. carotid arteries and optic nerves) to pituitary tumours, and any unintended damage can lead to severe complications including blindness and death. Intraoperative guidance during this surgery could support improved localization of the critical structures leading to reducing the risk of complications...
March 25, 2024: International Journal of Computer Assisted Radiology and Surgery
https://read.qxmd.com/read/38528034/research-on-helmet-wearing-detection-method-based-on-deep-learning
#17
JOURNAL ARTICLE
Lihong Wei, Panpan Liu, Haihui Ren, Dong Xiao
The vigorous development of the construction industry has also brought unprecedented safety risks. The wearing of safety helmets at the construction site can effectively reduce casualties. As a result, this paper suggests employing a deep learning-based approach for the real-time detection of safety helmet usage among construction workers. Based on the selected YOLOv5s network through experiments, this paper analyzes its training results. Considering its poor detection effect on small objects and occluded objects...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38527112/effectiveness-of-computerized-cognitive-training-on-working-memory-in-pediatric-cancer-survivors-a-systematic-review-and-meta-analysis
#18
JOURNAL ARTICLE
Katherine K W Lam, K Y Ho, Anthony P K Liu, Charlotte Q Liu, Ming Hong Ng, Ting Chak Lam, Getaneh Mulualem Belay, Abu-Odah Hammoda, Funa Yang, Wai Man Yuen, Godfrey C F Chan
BACKGROUND: Interactive features of computerized cognitive training (CCT) may enhance adherence to training, providing a relatively low-cost intervention. A robust systematic review on the effectiveness of CCT for improving working memory (WM) among pediatric survivors with cancer is lacking. OBJECTIVE: To summarize the available evidence and determine the effectiveness of CCT for WM among pediatric survivors with cancer. INTERVENTIONS/METHODS: Five databases were searched...
March 25, 2024: Cancer Nursing
https://read.qxmd.com/read/38526983/the-improved-backward-compatible-physics-informed-neural-networks-for-reducing-error-accumulation-and-applications-in-data-driven-higher-order-rogue-waves
#19
JOURNAL ARTICLE
Shuning Lin, Yong Chen
Due to the dynamic characteristics of instantaneity and steepness, employing domain decomposition techniques for simulating rogue wave solutions is highly appropriate. Wherein, the backward compatible physics-informed neural network (bc-PINN) is a temporally sequential scheme to solve PDEs over successive time segments while satisfying all previously obtained solutions. In this work, we propose improvements to the original bc-PINN algorithm in two aspects based on the characteristics of error propagation. One is to modify the loss term for ensuring backward compatibility by selecting the earliest learned solution for each sub-domain as pseudo-reference solution...
March 1, 2024: Chaos
https://read.qxmd.com/read/38525682/intraoperative-measurement-of-insertion-speed-in-cochlear-implant-surgery-a-preliminary-experience-with-cochlear-smartnav
#20
JOURNAL ARTICLE
Stefano Concheri, Davide Brotto, Marzia Ariano, Antonio Daloiso, Valerio Maria Di Pasquale Fiasca, Flavia Sorrentino, Beatrice Coppadoro, Patrizia Trevisi, Elisabetta Zanoletti, Sebastiano Franchella
OBJECTIVES: The objectives were to present the real-time estimated values of cochlear implant (CI) electrode insertion speed (IS) during intraoperative sessions using the Cochlear Nucleus SmartNav System to assess whether this measure affected CI outcomes and to determine whether real-time feedback assists expert surgeons in achieving slow insertion. METHODS: The IS was measured in 52 consecutive patients (65 implanted ears) using the CI632 electrode. The IS values were analyzed in relation to procedure repetition over time, NRT ratio, and CI audiological outcomes...
February 22, 2024: Audiology Research
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