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https://www.readbyqxmd.com/read/29666126/domains-of-health-related-quality-of-life-in-age-related-macular-degeneration-a-qualitative-study-in-the-chinese-cultural-context
#1
Wei Bian, Junli Wan, Graeme Smith, Shiying Li, Mingqiong Tan, Fengjiao Zhou
OBJECTIVE: To explore which areas of health-related quality of life were affected in Chinese patients, and to identify whether the areas are well covered by validated questionnaires. DESIGN: A qualitative study based on semistructured interviews was conducted. A qualitative thematic analysis following the approach of Colaizzi was used to analyse the interview data for significant statements and phrases. The themes and subthemes organised from the analysis were then compared by using the following current instruments: National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), Macular Disease Quality of life Questionnaire (MacDQoL) and Low-Luminance Questionnaire (LLD)...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29665696/nosographic-analysis-of-osmophobia-and-field-testing-of-diagnostic-criteria-including-osmophobia
#2
Mona Ameri Chalmer, Thomas Folkmann Hansen, Jes Olesen
Introduction Osmophobia has been suggested as an additional symptom of migraine without aura, and a high prevalence of osmophobia of up to 50% has been reported in the literature. We conducted a nosographic study of osmophobia in all migraineurs and tension-type headache patients and a field testing of suggested diagnostic criteria of osmophobia, presented in the appendix of the second edition of The International Classification of Headache Disorders and suggested by Silva-Néto et al. and Wang et al ., in migraine without aura and tension-type headache patients (n = 1934)...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29665080/clustering-of-motor-and-nonmotor-traits-in-leucine-rich-repeat-kinase-2-g2019s-parkinson-s-disease-nonparkinsonian-relatives-a-multicenter-family-study
#3
Tiago A Mestre, Claustre Pont-Sunyer, Farah Kausar, Naomi P Visanji, Taneera Ghate, Barbara S Connolly, Carmen Gasca-Salas, Drew S Kern, Jennifer Jain, Elizabeth J Slow, Achinoam Faust-Socher, Meike Kasten, Pettarusp M Wadia, Cindy Zadikoff, Prakash Kumar, Ronald M de Bie, Teri Thomsen, Anthony E Lang, Birgitt Schüle, Christine Klein, Eduardo Tolosa, Connie Marras
OBJECTIVES: The objective of this study was to determine phenotypic features that differentiate nonparkinsonian first-degree relatives of PD leucine-rich repeat kinase 2 (LRRK2) G2019S multiplex families, regardless of carrier status, from healthy controls because nonparkinsonian individuals in multiplex families seem to share a propensity to present neurological features. METHODS: We included nonparkinsonian first-degree relatives of LRRK2 G2019S familial PD cases and unrelated healthy controls participating in established multiplex family LRRK2 cohorts...
April 17, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29664840/malignant-ascites-validation-of-a-novel-ascites-symptom-mini-scale-for-use-in-patients-with-ovarian-cancer
#4
Ram Eitan, Oded Raban, Daliah Tsoref, Ariella Jakobson-Setton, Gad Sabah, Lina Salman, Effi Yeoshua, Avi Ben-Haroush
BACKGROUND: Ascites is a common finding in patients with ovarian cancer. Paracentesis is a relatively simple, safe, and effective procedure for draining fluid from the peritoneum, but valid quality-of-life tools are needed to determine its subjective value for alleviating symptoms and improving patient quality of life. The objective of this study was to prospectively evaluate the performance of a novel Ascites Symptom Mini-Scale (ASmS) and compare it with a previously available questionnaire...
April 16, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29664681/effect-of-bronchodilation-and-exercise-training-with-behavior-modification-on-exercise-tolerance-and-downstream-effects-on-symptoms-and-physical-activity-in-copd
#5
Thierry Troosters, François Maltais, Nancy Leidy, Kim L Lavoie, Maria Sedeno, Wim Janssens, Judith Garcia-Aymerich, Damijan Erzen, Dorothy De Sousa, Lawrence Korducki, Alan Hamilton, Jean Bourbeau
RATIONALE: Bronchodilation and exercise training (ExT) improve exercise tolerance in patients with chronic obstructive pulmonary disease (COPD); however, behavior modification is required to impact on daily physical activity (PA). OBJECTIVES: To assess whether tiotropium/olodaterol, ±ExT, would improve exercise endurance time (EET) and PA compared with placebo in patients participating in a self-management behavior-modification (SMBM) program. METHODS: A 12-week, randomized, partially double-blind, placebo-controlled, parallel-group trial in patients with COPD (PHYSACTO®; NCT02085161)...
April 17, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29662707/percutaneous-ethanol-injection-in-combination-with-laser-ablation-for-a-100-ml-partially-cystic-thyroid-nodule
#6
Roberto Negro, Gabriele Greco
Until nonsurgical techniques like laser ablation (LA) or radiofrequency became available, patients suffering from large nodules with compressive symptoms were addressed to surgery. We describe the case of a 59-year-old woman with a large, partially cystic thyroid nodule having a volume of about 100 ml. As the patient refused surgery, despite her constant local discomfort, such large partially cystic nodule underwent several percutaneous ethanol injections (PEI) and then was submitted to LA. The combination of these two procedures allowed firstly complete disappearance of the cystic component and secondly a significant reduction of thyroid nodule, which finally measured 17 ml in volume (82% reduction compared to baseline)...
2018: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/29661500/severity-of-eczema-and-mental-health-problems-in-japanese-schoolchildren-the-tommo-child-health-study
#7
Yasutaka Kuniyoshi, Masahiro Kikuya, Masako Miyashita, Chizuru Yamanaka, Mami Ishikuro, Taku Obara, Hirohito Metoki, Naoki Nakaya, Fuji Nagami, Hiroaki Tomita, Atsushi Hozawa, Ichiro Tsuji, Shigeo Kure, Nobuo Yaegashi, Masayuki Yamamoto, Shinichi Kuriyama
BACKGROUND: The association between eczema and mental health problems in schoolchildren has been underexplored. We aimed to investigate this association with the validated questionnaires. METHODS: Of 46,648 invited children, we analyzed 9954 (21.3%) in the 2nd to the 8th grades from the ToMMo Child Health Study conducted in 2014 and 2015, a cross-sectional survey in Miyagi Prefecture, Japan. We defined eczema status as "normal," "mild/moderate," or "severe," based on the presence of persistent flexural eczema and sleep disturbance, according to the International Study of Asthma and Allergies in Childhood (ISAAC) Eczema Symptom Questionnaire...
April 13, 2018: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/29660770/psychological-therapy-for-inpatients-receiving-acute-mental-health-care-a-systematic-review-and-meta-analysis-of-controlled-trials
#8
Charlotte Paterson, Thanos Karatzias, Adele Dickson, Sean Harper, Nadine Dougall, Paul Hutton
OBJECTIVES: The effectiveness of psychological therapies for those receiving acute adult mental health inpatient care remains unclear, partly because of the difficulty in conducting randomized controlled trials (RCTs) in this setting. The aim of this meta-analysis was to synthesize evidence from all controlled trials of psychological therapy carried out with this group, to estimate its effects on a number of important outcomes and examine whether the presence of randomization and rater blinding moderated these estimates...
April 16, 2018: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/29660578/implementing-the-risk-of-endometrial-malignancy-algorithm-rem-adding-obesity-as-a-predictive-factor-results-of-rem-b-in-a-single-center-survey
#9
Francesco Plotti, Stella Capriglione, Giuseppe Scaletta, Daniela Luvero, Salvatore Lopez, Francesca Fiori Nastro, Corrado Terranova, Carlo De Cicco Nardone, Roberto Montera, Roberto Angioli
OBJECTIVE: In 2013, our group assessed a risk stratification tool of endometrial cancer (EC), called REM (Risk of Endometrial Malignancy). A well known risk factor for EC is body mass index (BMI). In fact, (BMI > 30 and <35 kg/m2) and severe obesity (BMI > 35 kg/m2) were associated with a 2.6-fold and a 4.7-fold increase in EC risk, respectively. Therefore, in the present study we aim to improve the performance of REM, including BMI and developing a new scoring system, called REM-B (Risk of Endometrial Malignancy score associated to BMI), to classify patients into high risk or low risk groups for EC...
April 7, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29660151/hangover-in-post-college-aged-drinkers-psychometric-properties-of-the-hangover-symptom-scale-hss-and-the-hangover-symptom-scale-short-form-hss-5
#10
Jesus Chavarria, Sandra Y Rueger, Andrea C King
BACKGROUND: Alcohol hangovers have been found to be a common and costly consequence of alcohol misuse. However, there is only limited psychometric support for instruments to accurately measure hangovers beyond the college-age years. This study investigated the psychometric properties of the Hangover Symptom Scale (HSS) and the Hangover Symptom Scale-Short Form (HSS-5) including the internal consistency, convergent and discriminant validity, construct validity, and the measurement invariance of these scales between light and heavy drinkers, individuals with a positive and negative family history of alcohol use disorder (AUD), and men and women in a post-college-aged sample...
April 16, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29660036/effectiveness-of-exercise-therapy-in-the-management-of-wruld-in-sedentary-workers-a-systematic-review
#11
D Kelly, F Shorthouse, V Roffi, C Tack
Background: Work-related upper limb disorders (WRULDs) are a syndrome of symptoms affecting the upper quadrant of the body and are a significant cause of pain, disability and sickness absence among workers. Exercise therapy is considered to be a clinical and cost-effective strategy in WRULD management. Aims: To evaluate the effectiveness of exercise therapy for WRULDs in sedentary workers. Methods: This review follows an a priori protocol to maintain internal validity describing essential procedures to be followed (e...
April 11, 2018: Occupational Medicine
https://www.readbyqxmd.com/read/29659857/evaluation-of-a-recommender-app-for-apps-for-the-treatment-of-depression-and-anxiety-an-analysis-of-longitudinal-user-engagement
#12
Ken Cheung, Wodan Ling, Chris J Karr, Kenneth Weingardt, Stephen M Schueller, David C Mohr
Objective: While depression and anxiety are common mental health issues, only a small segment of the population has access to standard one-on-one treatment. The use of smartphone apps can fill this gap. An app recommender system may help improve user engagement of these apps and eventually symptoms. Methods: IntelliCare was a suite of apps for depression and anxiety, with a Hub app that provided app recommendations aiming to increase user engagement. This study captured the records of 8057 users of 12 apps...
April 6, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29658378/improvement-of-depressive-symptoms-in-patients-with-moderate-to-severe-psoriasis-treated-with-ustekinumab-an-open-label-trial-validated-using-beck-depression-inventory-hamilton-depression-rating-scale-measures-and-18-fluorodeoxyglucose-fdg-positron-emission
#13
Seong-Jang Kim, Min-Young Park, Kyoungjune Pak, Junhee Han, Gun-Wook Kim, Hoon-Soo Kim, Hyun-Chang Ko, Moon-Bum Kim, Byung-Soo Kim
BACKGROUND: Psoriasis is a chronic skin disease associated with psychiatric co-morbidities, especially depression. Early detection of psychological vulnerability in patients with psoriasis seems to be of great clinical importance and significantly impacts the quality of life of the patients. OBJECTIVES: We sought to clarify the association between psoriasis and depressive symptoms in patients with moderate to severe psoriasis, and to determine the risk factors for depressive symptoms and analyse the effect of ustekinumab on the symptoms...
April 16, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29657874/the-reliability-and-validity-of-the-turkish-version-of-the-fibromyalgia-participation-questionnaire
#14
Lale Altan, Reyhan Çeliker, İlker Ercan, Murat Birtane, Kenan Akgün, Coşkun Zateri, Nurettin Taştekin, Aylin Rezvani, İlknur Aktaş, Şenay Özdolap, Erbil Dursun, Nigar Dursun, Selda Sarıkaya
Objective: The objective of this study was to test the reliability and validity of the Turkish version of the Fibromyalgia Participation Questionnaire (FPQ). Methods: One hundred and eighty-four female patients with fibromyalgia syndrome were included in the study. All patients filled out the Turkish FPQ (FPQ-T) questionnaire, which was obtained by translation from German according to the guideline for the process of cross-cultural adaptation The patients filled out the revised Fibromyalgia Impact Questionnaire (FIQ) and reevaluated the FPQ-T two hours later...
March 2018: European Journal of Rheumatology
https://www.readbyqxmd.com/read/29656729/-false-positive-self-reported-psychotic-experiences-in-the-general-population-an-investigation-of-outcome-predictive-factors-and-clinical-relevance
#15
Y van der Steen, I Myin-Germeys, M van Nierop, M Ten Have, R de Graaf, S van Dorsselaer, J van Os, R van Winkel
AIMS: Self-reported psychotic experiences (SRPE) by individuals from the general population are often unconfirmed by clinical interview and referred to as 'false-positive' (FP) SRPE. FP SRPE have been suggested to represent the mildest form of risk along the extended psychosis continuum. However, little is known about their (clinical) outcome and evolution over time. Aims of this study were to prospectively examine, in individuals with FP SRPE, (1) the prevalence of remission, persistence and transition to validated PE at 3-year follow-up; (2) potential baseline psychopathological and psychosocial predictors of persistence of FP SRPE and transition to validated PE; and (3) whether those with persistent FP SRPE and validated PE already differed on psychopathology and psychosocial factors at baseline...
April 16, 2018: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/29656064/a-prospective-study-of-patient-reported-pain-after-bulbar-urethroplasty
#16
Patrick Evans, Sorena Keihani, Benjamin N Breyer, Bradley A Erickson, James M Hotaling, Sara M Lenherr, Jeremy B Myers
PURPOSE: To understand the prevalence of chronic perineal pain, activity limitations, and patient satisfaction after urethroplasty. METHODS: From 2014-2016, we prospectively enrolled men undergoing urethroplasty for bulbar urethral strictures. Patients, before and after surgery, completed questions from the Core Lower Urinary Tract Symptom Score (CLSS) assessing pain frequency in the bladder and penis/urethra, as well as non-validated questions assessing perineal pain...
April 12, 2018: Urology
https://www.readbyqxmd.com/read/29655386/a-comparative-network-analysis-of-eating-disorder-psychopathology-and-co-occurring-depression-and-anxiety-symptoms-before-and-after-treatment
#17
Kathryn E Smith, Tyler B Mason, Ross D Crosby, Li Cao, Rachel C Leonard, Chad T Wetterneck, Brad E R Smith, Nicholas R Farrell, Bradley C Riemann, Stephen A Wonderlich, Markus Moessner
BACKGROUND: Network analysis is an emerging approach in the study of psychopathology, yet few applications have been seen in eating disorders (EDs). Furthermore, little research exists regarding changes in network strength after interventions. Therefore the present study examined the network structures of ED and co-occurring depression and anxiety symptoms before and after treatment for EDs. METHOD: Participants from residential or partial hospital ED treatment programs (N = 446) completed assessments upon admission and discharge...
April 15, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29653458/-assessment-of-couples-communication-in-patients-with-advanced-cancer-validation-of-a-german-version-of-the-couple-communication-scale-ccs
#18
Martina Conrad, Dorit Engelmann, Michael Friedrich, Katharina Scheffold, Rebecca Philipp, Frank Schulz-Kindermann, Martin Härter, Anja Mehnert, Susan Koranyi
BACKGROUND: There are only a few valid instruments measuring couples' communication in patients with cancer for German speaking countries. The Couple Communication Scale (CCS) represents an established instrument to assess couples' communication. However, there is no evidence regarding the psychometric properties of the German version of the CCS until now and the assumed one factor structure of the CCS was not verified for patients with advanced cancer yet. METHOD: The CCS was validated as a part of the study "Managing cancer and living meaningfully" (CALM) on N=136 patients with advanced cancer (≥18 years, UICC-state III/IV)...
April 13, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29652785/clinical-prediction-rule-for-heterotopic-ossification-of-the-hip-in-patients-with-spinal-cord-injury
#19
Eduardo M Suero, Mustafa Citak
STUDY DESIGN: Case-control study; clinical prediction rule. OBJECTIVE: To construct and internally validate a clinical prediction rule to identify patients at high risk of developing heterotopic ossification (HO) after spinal cord injury (SCI). SUMMARY OF BACKGROUND DATA: HO after SCI can lead to loss of joint mobility, loss of function, peripheral nerve entrapment, and pressure sores. HO is usually diagnosed based on clinical symptoms, as no laboratory tests are yet available to identify patients with early HO formation...
April 12, 2018: Spine
https://www.readbyqxmd.com/read/29652736/recommendations-and-extraction-of-clinical-variables-of-pediatric-multiple-sclerosis-using-common-data-elements
#20
Pamela Newland, John M Newland, Verna L Hendricks-Ferguson, Judith M Smith, Brant J Oliver
PURPOSE: The purpose of this article was to demonstrate the feasibility of using common data elements (CDEs) to search for information on the pediatric patient with multiple sclerosis (MS) and provide recommendations for future quality improvement and research in the use of CDEs for pediatric MS symptom management strategies Methods: The St. Louis Children's Hospital (SLCH), Washington University (WU) pediatrics data network was evaluated for use of CDEs identified from a database to identify variables in pediatric MS, including the key clinical features from the disease course of MS...
April 12, 2018: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
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