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https://www.readbyqxmd.com/read/29909603/urinary-outcomes-in-patients-with-down-s-syndrome-and-hirschsprung-s-disease
#1
Alexander Johannes Martinus Dingemans, Carlos Albert Reck-Burneo, Molly Fuchs, Alejandra Vilanova Sanchez, Victoria Alison Lane, Erin Hoover, Tassiana Maloof, Laura Weaver, Marc A Levitt, Richard J Wood
INTRODUCTION:  Previous research in children with Hirschsprung's disease (HD) and Down's syndrome (DS) has focused on colorectal outcomes. We set out to review urinary outcomes in this patient group. METHODS:  The medical records of all patients aged five years and older with HD were reviewed, and patients and caregivers filled out the Vancouver Symptom Score at intake, which is designed and validated to diagnose dysfunctional elimination syndrome. RESULTS:  A total of 104 patients with HD were included in this study...
June 17, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29909413/validity-and-reliability-of-the-dutch-adaptation-of-the-actinic-keratosis-quality-of-life-questionnaire-akqol
#2
Kelly Vis, Rick Waalboer-Spuij, Dyon G C T M Snels, Loes M Hollestein
BACKGROUND: The Actinic Keratosis Quality of Life Questionnaire (AKQoL) is a disease-specific instrument to measure the impact of actinic keratosis (AK) on patients' lives. OBJECTIVE: To validate and test the psychometric properties of the AKQoL translated into the Dutch language (AKQoL-NL). METHODS: All new patients ≥50 years of age with untreated AK in a university medical center and a general hospital between August 2014 and August 2015 were eligible...
June 15, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29909302/affective-styles-in-mood-and-anxiety-disorders-clinical-validation-of-the-affective-style-questionnaire-asq
#3
Christina Totzeck, Tobias Teismann, Stefan G Hofmann, Ruth von Brachel, Xiao Chi Zhang, Verena Pflug, Jürgen Margraf
BACKGROUND: Emotion regulation plays a critical role in the development and maintenance of psychological disorders. Less is known about the association of affective styles and psychopathology. The 20-item "Affective Style Questionnaire" (ASQ) has been validated in nonclinical samples. The American and German validation studies resulted in a three-factor structure (concealing, adjusting, and tolerating). The present study aimed to investigate three aspects: (1) the validation of the ASQ within a clinical sample, (2) the examination of possible differences in affective styles between patients suffering from affective versus anxiety disorders, and (3) the association of affective styles and anxiety, depression, and stress symptoms...
June 2, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29909127/structural-validity-of-the-maslach-burnout-inventory-and-influence-of-depressive-symptoms-in-banking-workplace-unfastening-the-occupational-conundrum
#4
Maria do Socorro da Silva Valente, Yuan-Pang Wang, Paulo Rossi Menezes
Burnout and mental disorders have been reported in the financial industry. This study aims to examine the structural validity of the Maslach Burnout Inventory (MBI) and to investigate the connection between the dimensions of burnout and depressive symptoms in a sample of 1046 bank employees from North Brazil who completed the MBI and the Patient Health Questionnaire-9 (PHQ-9. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were used to cross-check the factorial structure of the MBI...
June 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29908389/development-and-validation-of-a-clinical-prediction-tool-to-estimate-the-individual-risk-of-depressive-relapse-or-recurrence-in-individuals-with-recurrent-depression
#5
Nicola S Klein, Gea A Holtman, Claudi L H Bockting, Martijn W Heymans, Huibert Burger
OBJECTIVES: Many studies examined predictors of depressive relapse/recurrence but no simple tool based on well-established risk factors is available that estimates the risk within an individual. We developed and validated such a prediction tool in remitted recurrently depressed individuals. METHODS: The tool was developed using data (n = 235) from a pragmatic randomised controlled trial in remitted recurrently depressed participants and externally validated using data (n = 209) from a similar randomised controlled trial of remitted recurrently depressed participants using maintenance antidepressants...
June 8, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29908378/vitamin-d-deficiency-and-lower-urinary-tract-symptoms-in-women
#6
H Aydogmus, U S Demirdal
OBJECTIVE: The association of vitamin D deficiency and pelvic floor dysfunction has been examined by numerous studies. Lower urinary tract symptoms (LUTS) associated with bladder filling and voiding functions are common in both sexes. A recent study reports a higher incidence of LTUS in men over 50 years old with vitamin D deficiency. The aim of the study is to investigate whether there is a difference in the Lower Urinary Tract Symptoms frequency between women with vitamin D deficiency and the control group or not...
June 9, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29908296/sonographically-guided-plantaris-tendon-release-a-cadaveric-validation-study
#7
Jay Smith, Håkan Alfredson, Lorenzo Masci, Jacob L Sellon, Charonn D Woods
BACKGROUND: The plantaris tendon (PT) has been implicated in the pathogenesis of symptoms in a subset of patients with Achilles region pain syndromes and has been traditionally managed via open surgical resection. Although the PT can be visualized on ultrasound, a minimally invasive technique for sonographically guided PT release has not been formally described. OBJECTIVE: To validate a technique to perform sonographically guided PT release in an unembalmed cadaveric model...
June 13, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29907988/self-reassurance-not-self-esteem-serves-as-a-buffer-between-self-criticism-and-depressive-symptoms
#8
Nicola Petrocchi, Francesco Dentale, Paul Gilbert
OBJECTIVES: Several studies suggest that self-criticism and self-reassurance operate through different mechanisms and might interact with each other. This study examined the hypothesis that self-reassurance serves as a buffer between self-criticism and depressive symptoms in a way that self-esteem, which is rooted in a different motivational system, may not. DESIGN: We hypothesized that self-criticism would be correlated with high levels of depressive symptoms, but that this association would be weaker at higher levels of self-reassurance abilities...
June 15, 2018: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29907667/symptoms-of-autonomic-dysfunction-in-systemic-sclerosis-assessed-by-the-compass-31-questionnaire
#9
Brittany L Adler, James W Russell, Laura K Hummers, Zsuzsanna H McMahan
OBJECTIVE: Autonomic dysfunction is a known complication of systemic sclerosis (SSc) that can affect vascular tone, gastrointestinal (GI) motility, heart rate, and blood pressure control. We sought to quantify autonomic symptom burden in SSc, and to define the characteristics of patients with SSc and autonomic dysfunction. METHODS: Patients with SSc were consecutively recruited during routine clinical visits at the Johns Hopkins Scleroderma Center and asked to complete the Composite Autonomic Symptom Score (COMPASS)-31 questionnaire, a validated tool to assess symptoms of autonomic dysfunction...
June 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29907560/validation-of-a-natural-language-processing-algorithm-for-detecting-infectious-disease-symptoms-in-primary-care-electronic-medical-records-in-singapore
#10
Antony Hardjojo, Arunan Gunachandran, Long Pang, Mohammed Ridzwan Bin Abdullah, Win Wah, Joash Wen Chen Chong, Ee Hui Goh, Sok Huang Teo, Gilbert Lim, Mong Li Lee, Wynne Hsu, Vernon Lee, Mark I-Cheng Chen, Franco Wong, Jonathan Siung King Phang
BACKGROUND: Free-text clinical records provide a source of information that complements traditional disease surveillance. To electronically harness these records, they need to be transformed into codified fields by natural language processing algorithms. OBJECTIVE: The aim of this study was to develop, train, and validate Clinical History Extractor for Syndromic Surveillance (CHESS), an natural language processing algorithm to extract clinical information from free-text primary care records...
June 11, 2018: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29907384/quality-of-life-and-parkinson-s-disease-philippine-translation-and-validation-of-the-parkinson-s-disease-questionnaire
#11
Cezar Thomas R Suratos, Gerard Raimon M Saranza, Derick Erl P Sumalapao, Roland Dominic G Jamora
The 39-item Parkinson's Disease Quality of Life Questionnaire (PDQ-39) is the most widely used self-administered questionnaire assessing the quality of life of Parkinson's disease (PD) patients. We translated the PDQ-39 into the Filipino language as the Philippine-PDQ-39 (P-PDQ-39) and used it to assess the quality of life of Filipino patients with PD. The original PDQ-39 was translated into Filipino using forward and backward translation by independent bilingual translators and used among 100 consecutively sampled PD patients...
June 12, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29907147/health-related-quality-of-life-of-preterm-born-children-at-three-years-in-a-sub-urban-district-in-sri-lanka-a-retrospective-cohort-study
#12
Hemali Jayakody, Upul Senarath, Deepika Attygalle
BACKGROUND: Preterm birth leads to multiple morbidities affecting the health of a child. Lack of information on the health impact of prematurity hinders the possibility of any effective public health interventions in this regard. Our aim was to determine the association between preterm birth and Health-Related Quality of Life (HRQOL) among 3 years old children in the Gampaha district, Sri Lanka. METHODS: A community-based retrospective cohort study was conducted among 790 preterm and term born children who were 03 years old...
June 15, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29906707/comorbid-depression-and-associated-factors-in-pnes-versus-epilepsy-systematic-review-and-meta-analysis
#13
REVIEW
Sean Walsh, Liat Levita, Markus Reuber
OBJECTIVES: This systematic review aims to contrast levels, manifestations and associations of depression in patients with psychogenic non-epileptic seizures (PNES) and those with epilepsy. METHODS: ScienceDirect and Web of Science were searched for primary research reports describing quantitative studies involving separate epilepsy and PNES samples (age 16+) and using a validated measure of depression. RESULTS: While 34 studies were identified, most were of low quality and had small sample sizes...
May 24, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29906681/reliability-and-validity-of-the-self-report-version-of-the-apathy-evaluation-scale-in-first-episode-psychosis-concordance-with-the-clinical-version-at-baseline-and-12-months-follow-up
#14
Ann Faerden, Siv Hege Lyngstad, Carmen Simonsen, Petter Andreas Ringen, Oleg Papsuev, Ingrid Dieset, Ole A Andreassen, Ingrid Agartz, Stephen R Marder, Ingrid Melle
Negative symptoms have traditionally been assessed based on clinicians' observations. The subjective experience of negative symptoms in people with psychosis may bring new insight. The Apathy Evaluation Scale (AES) is commonly used to study apathy in psychosis and has corresponding self-rated (AES-S) and clinician-rated (AES-C) versions. The aim of the present study was to determine the validity and reliability of the AES-S by investigating its concordance with the AES-C. Eighty-four first-episode (FEP) patients completed the shortened 12-item AES-S and AES-C at baseline (T1) and 12 months (T2)...
May 31, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29904913/mir-128-1-5p-regulates-tight-junction-induced-by-selenium-deficiency-via-targeting-cell-adhesion-molecule-1-in-broilers-vein-endothelial-cells
#15
Tingru Pan, Xueyuan Hu, Tianqi Liu, Zhe Xu, Na Wan, Yiming Zhang, Shu Li
Vein endothelial cells (VECs) constitute an important barrier for macromolecules and circulating cells from the blood to the tissues, stabilizing the colloid osmotic pressure of the blood, regulating the vascular tone, and rapidly changing the intercellular connection, and maintaining normal physiological function. Tight junction has been discovered as an important structural basis of intercellular connection and may play a key role in intercellular connection injuries or vascular diseases and selenium (Se) deficiency symptoms...
June 15, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29904599/preparation-of-organotypic-brain-slice-cultures-for-the-study-of-alzheimer-s-disease
#16
Cara L Croft, Wendy Noble
Alzheimer's disease, the most common cause of dementia, is a progressive neurodegenerative disorder characterised by amyloid-beta deposits in extracellular plaques, intracellular neurofibrillary tangles of aggregated tau, synaptic dysfunction and neuronal death. There are no cures for AD and current medications only alleviate some disease symptoms. Transgenic rodent models to study Alzheimer's mimic features of human disease such as age-dependent accumulation of abnormal beta-amyloid and tau, synaptic dysfunction, cognitive deficits and neurodegeneration...
2018: F1000Research
https://www.readbyqxmd.com/read/29904445/malignant-ventricular-arrhythmias-resulting-from-drug-induced-qtc-prolongation-a-retrospective-study
#17
Renato De Vecchis, Carmelina Ariano, Giuseppina Di Biase, Michel Noutsias
Background: Several drug classes (antiarrhythmics, antimicrobials, antidepressants, phenothiazines, opiates, prokinetics of digestive tract, etc.) have been related to ventricular hyperkinetic arrhythmias such as torsade de pointes (TdP). TdPs are usually heralded by an abnormal prolongation of heart rate-corrected QT interval on the electrocardiogram, so-called drug-induced long heart rate-corrected QT (diLQTc). We don't know to what extent the drug-induced QTc prolongation is able to predict malignant arrhythmias...
July 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29904014/is-it-time-to-change-the-definition-of-acute-exacerbation-of-chronic-obstructive-pulmornary-disease-what-do-we-need-to-add
#18
REVIEW
Maria Montes de Oca, Maria Eugenia Laucho-Contreras
Acute exacerbations in chronic obstructive pulmonary disease (AECOPD) are associated with increased mortality, rate of hospitalization, use of healthcare resources, and have a negative impact on disease progression, quality of life and lung function of patients with chronic obstructive pulmonary disease (COPD). There is an imperative need to homogenize the definition of AECOPD because the incidence of exacerbations has a significant influence or implication on treatment decision making, particularly in pharmacotherapy and could impact the outcome or change the statistical significance of a therapeutic intervention in clinical trials...
June 14, 2018: Medical Sciences: Open Access Journal
https://www.readbyqxmd.com/read/29902985/prevalence-and-determinants-of-antepartum-depressive-and-anxiety-symptoms-in-expectant-mothers-and-fathers-results-from-a-perinatal-psychiatric-morbidity-cohort-study-in-the-east-and-west-coasts-of-malaysia
#19
Hashima E Nasreen, Jamalludin Ab Rahman, Razman Mohd Rus, Mira Kartiwi, Rosnah Sutan, Maigun Edhborg
BACKGROUND: Research on antepartum psychiatric morbidities investigating depressive and anxiety symptoms in expectant mothers and fathers is lacking in low- and middle-income countries. This study aimed to estimate the prevalence of antepartum depressive, anxiety and co-occurring significant symptoms and explore the associated factors in a cross-section of Malaysian expectant mothers and fathers. METHODS: We used cross-sectional data from a prospective cohort study of 911 expectant mothers and 587 expectant fathers during their third trimester of pregnancy, from health clinics of two states in the east and west coasts of Malaysia...
June 15, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29902734/depressive-symptoms-handgrip-strength-and-weight-status-in-us-older-adults
#20
Lee Smith, Stephanie White, Brendon Stubbs, Liang Hu, Nicola Veronese, Davy Vancampfort, Mark Hamer, Benjamin Gardner, Lin Yang
BACKGROUND: Handgrip strength is a valid indicator of broader physical functioning. Handgrip strength and weight status have been independently associated with depressive symptoms in older adults, but no study has yet investigated the relationships between all three in older US adults. This study investigated the relationship between physical function and depressive symptoms by weight status in older US adults. METHODS: Cross-sectional data were analysed from the National Health and Nutrition Examination Survey waves 2011 to 2012 and 2013 to 2014...
June 5, 2018: Journal of Affective Disorders
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