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https://www.readbyqxmd.com/read/28898891/new-insights-into-the-natural-history-of-congenital-zika-virus-syndrome
#1
María Guadalupe Lovagnini Frutos, José Héctor Ochoa, María Gabriela Barbás, Héctor Dante Lucchini, Martín Moya, Gustavo Malinger
We describe the prenatal evolution of the brain findings in a patient with proved Zika virus infection at 8 weeks of gestation showing the very early appearance at 17 weeks of ventriculomegaly and signs of brain parenchymal involvement without microcephaly. The involvement of the brain becomes more evident at 22 and 27 weeks with the apparition of calcifications and microcephaly. Interestingly, the postnatal findings failed to show significant worsening when compared to these prenatal findings.
September 13, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28898865/automatic-measurement-of-fetal-brain-development-from-magnetic-resonance-imaging-new-reference-data
#2
Daphna Link, Michael B Braginsky, Leo Joskowicz, Liat Ben Sira, Shaul Harel, Ariel Many, Ricardo Tarrasch, Gustavo Malinger, Moran Artzi, Cassandra Kapoor, Elka Miller, Dafna Ben Bashat
BACKGROUND: Accurate fetal brain volume estimation is of paramount importance in evaluating fetal development. The aim of this study was to develop an automatic method for fetal brain segmentation from magnetic resonance imaging (MRI) data, and to create for the first time a normal volumetric growth chart based on a large cohort. SUBJECTS AND METHODS: A semi-automatic segmentation method based on Seeded Region Growing algorithm was developed and applied to MRI data of 199 typically developed fetuses between 18 and 37 weeks' gestation...
September 13, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28895090/effort-and-neuropsychological-performance-in-hiv-infected-individuals-on-stable-combination-antiretroviral-therapy
#3
Robert Paul, Gina Rhee, Laurie M Baker, Florin Vaida, Sarah A Cooley, Beau M Ances
The expression of cognitive symptoms associated with HIV varies over time and across individuals. This pattern may reflect transient contextual factors, including the degree of effort exerted by individuals undergoing cognitive testing. The present study examined whether effort corresponds to the expression of persistent HIV-related cognitive impairment among individuals receiving combination antiretroviral therapy (cART). HIV+ individuals (n = 111) averaged 48.2 (14.9) years of age and 13.0 (2.7) years of education and HIV- individuals (n = 92) averaged 34...
September 11, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28884614/characteristics-of-inmates-who-misuse-prescription-medication
#4
Anthony C Tamburello, Archana Kathpal, Rusty Reeves
Substance use disorders are common among incarcerated individuals, and prescribed medications have been reported as abused, diverted, or otherwise misused in correctional settings. We conducted a retrospective chart review of electronic medical records and reports on institutional charges for misuse of authorized medication by inmates in the New Jersey Department of Corrections between 2003 and 2013. The most frequently cited medications for misuse were gabapentin, diphenhydramine, clonidine, and ibuprofen...
January 1, 2017: Journal of Correctional Health Care
https://www.readbyqxmd.com/read/28867167/pediatric-acute-megakaryoblastic-leukemia-multitasking-fusion-proteins-and-oncogenic-cooperations
#5
REVIEW
Cécile K Lopez, Sébastien Malinge, Muriel Gaudry, Olivier A Bernard, Thomas Mercher
Pediatric leukemia presents specific clinical and genetic features from adult leukemia but the underpinning mechanisms of transformation are still unclear. Acute megakaryoblastic leukemia (AMKL) is the malignant accumulation of progenitors of the megakaryocyte lineage that normally produce blood platelets. AMKL is diagnosed de novo, in patients showing a poor prognosis, or in Down syndrome (DS) patients with a better prognosis. Recent data show that de novo AMKL is primarily associated with chromosomal alterations leading to the expression of fusions between transcriptional regulators...
September 2017: Trends in Cancer
https://www.readbyqxmd.com/read/28865254/-the-land-of-the-sick-and-the-land-of-the-healthy-disability-bureaucracy-and-stigma-among-people-living-with-poverty-and-chronic-illness-in-the-united-states
#6
Henry J Whittle, Kartika Palar, Nikhil A Ranadive, Janet M Turan, Margot Kushel, Sheri D Weiser
Disability benefits have become an increasingly prominent source of cash assistance for impoverished American citizens over the past two decades. This development coincided with cuts and market-oriented reforms to state and federal welfare programs, characteristic of the wider political-economic trends collectively referred to as neoliberalism. Recent research has argued that contemporary discourses on 'disability fraudsters' and 'malingerers' associated with this shift represent the latest manifestation of age-old stigmatization of the 'undeserving poor'...
August 26, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28864120/attitudes-towards-disclosing-a-mental-illness-among-german-soldiers-and-their-comrades
#7
Nicolas Rüsch, Carolyn Rose, Fabian Holzhausen, Nadine Mulfinger, Silvia Krumm, Patrick W Corrigan, Gerd-Dieter Willmund, Peter Zimmermann
Many soldiers with mental illness (SWMIs) struggle with the decision whether to disclose their condition in or outside the military. This study therefore explored views on (self-)labeling as 'mentally ill', experiences of discrimination and coping, risks and benefits of (non-)disclosure, service use, disclosure decisions and consequences of disclosing. Active-duty SWMIs as well as soldiers without mental illness (commanding officers; enlisted ranks) and military social workers participated in focus groups. Transcripts were analyzed using qualitative content analysis...
August 16, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28836450/validation-of-the-advanced-clinical-solutions-word-choice-test-wct-in-a-mixed-clinical-sample-establishing-classification-accuracy-sensitivity-specificity-and-cutoff-scores
#8
Kathleen M Bain, Jason R Soble
This study examined the Word Choice Test's (WCT) utility as a performance validity test in a mixed clinical sample of veterans referred for neuropsychological evaluation. Participants completed Green's Word Memory Test (WMT), WCT, and Test of Memory Malingering (TOMM) Trial 1. Using the WMT as the criterion for valid performance, logistic regressions examined the WCT and TOMM's classification accuracy for those with and without cognitive impairment (CI). Receiver operating characteristic curves were used to establish cut scores which maximized the sensitivity/specificity of each measure...
August 1, 2017: Assessment
https://www.readbyqxmd.com/read/28829250/form-vs-function-fighting-the-last-war-a-reflection-on-the-exchange-between-larrabee-bianchini-boone-and-rohling-2017-and-nichols-2017-over-nichols-and-gass-2015-the-fake-bad-scale-fbs-malingering-or-ligation-response-syndrome-which-is-it
#9
Paul A Arbisi
A reflection on the exchange between Larrabee et al. (2017) and Nichols (2017) is provided by a clinical psychologist who co-authored an early critique questioning the validity of the FBS as a measure of over reporting and who, based on subsequent studies demonstrating the effectiveness of the FBS in identifying non-credible report of somatic and cognitive complaints, changed his opinion regarding the utility of the FBS/FBS-r as a symptom validity measure. Given the accumulated evidence demonstrating the effectiveness of the FBS/FBS-r as a symptom validity measure, reasons for the continued debate over the validity and utility of the FBS/FBS-r are discussed...
August 22, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28826306/performance-on-the-test-of-memory-malingering-is-predicted-by-the-number-of-errors-on-its-first-10-items-on-an-inpatient-epilepsy-monitoring-unit
#10
Jonathan M Grabyan, Robert L Collins, W Alexander Alverson, David K Chen
OBJECTIVE: Performance validity testing is an increasingly vital component of neuropsychological evaluation, though administration of stand-alone performance validity tests (PVTs) can be time-consuming. As the Test of Memory Malingering (TOMM) is among the most commonly used and researched PVTs, much work has focused on creating abbreviated versions while preserving diagnostic accuracy. A recent addition to this effort, errors on the first 10 items of Trial 1 (TOMMe10), was analyzed for its utility in predicting TOMM performance...
August 22, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28816502/cost-of-malingering-mild-traumatic-brain-injury-related-cognitive-deficits-during-compensation-and-pension-evaluations-in-the-veterans-benefits-administration
#11
John H Denning, Robert D Shura
Given the high rates of exaggeration in those claiming long-term cognitive deficits as a result of mild traumatic brain injury (mTBI), the aim of this study was to evaluate the rates of malingering in those seeking disability through the Veterans Benefits Administration and estimate the financial burden of disability payments for those receiving compensation despite exaggerated mTBI-related cognitive deficits. Retrospective review included 74 veterans seen for Compensation and Pension evaluations for mTBI. Rates of malingering were based on failure of the Medical Symptom Validity Test (MSVT) and/or the Test of Memory Malingering (TOMM) trial 1 ≤ 40...
August 17, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28661193/-you-want-to-show-you-re-a-valuable-employee-a-critical-discourse-analysis-of-multi-perspective-portrayals-of-employed-women-with-fibromyalgia
#12
Margaret Oldfield, Ellen MacEachen, Margaret MacNeill, Bonnie Kirsh
Background Advice on fibromyalgia, a chronic illness primarily affecting women, often presents it as incompatible with work and rarely covers how to remain employed. Yet many women do. Objectives We aimed to understand how these women, their family members, and workmates portrayed employees with fibromyalgia, and how these portrayals helped women retain employment. Methods We interviewed 22 participants, comprising five triads and three dyads of people who knew each other. Using the methodology of critical discourse analysis, we analysed the interview data within and across the triads/dyads through coding, narrative summaries, and relational mapping...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/28657355/a-single-error-is-one-too-many-examining-alternative-cutoffs-on-trial-2-of-the-tomm
#13
Laszlo A Erdodi, Jaspreet K Rai
OBJECTIVE: This study investigated the potential of alternative, more liberal cutoffs on Trial 2 of the Test of Memory Malingering (TOMM) to improve classification accuracy relative to the standard cutoffs (≤44). METHOD: The sample consisted of 152 patients (49.3% male) with psychiatric conditions (PSY) and traumatic brain injury (TBI) referred for neuropsychological assessment in a medico-legal setting (MAge = 44.4, MEducation = 11.9 years). Classification accuracy for various TOMM Trial 2 cutoffs was computed against three criterion measures...
June 28, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28656801/the-vulnerability-of-self-reported-disability-measures-to-malingering-a-simulated-adhd-study
#14
Andrew M Bryant, Esther Lee, Ashley Howell, Brittni Morgan, Carolyn M Cook, Kruti Patel, Andrew Menatti, Rebekah Clark, Melissa T Buelow, Julie A Suhr
OBJECTIVE: Making diagnostic and accommodation decisions for potential Attention-Deficit/Hyperactivity Disorder (ADHD) in adults is difficult, as the assessor often relies more on self-reported symptoms and functional disability than in childhood evaluations. Malingering of ADHD occurs frequently in the educational setting and for a variety of reasons, including the potential benefits of access to stimulant medications and academic accommodations. METHOD: The present study utilized a simulation design to examine the potential for malingering of self-reported functional disability on the World Health Organization Disability Schedule 2...
June 28, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28656790/the-dot-counting-test-adds-up-validation-and-response-pattern-analysis-in-a-mixed-clinical-veteran-sample
#15
Jason R Soble, Octavio A Santos, Kathleen M Bain, Joshua W Kirton, K Chase Bailey, Edan A Critchfield, Justin J F O'Rourke, Jonathan M Highsmith, David Andrés González
OBJECTIVE: This study cross-validated the Dot Counting Test (DCT) as a performance validity test (PVT) among a mixed clinical veteran sample. Completion time and error patterns also were examined by validity group and cognitive impairment status. METHOD: This cross-sectional study included 77 veterans who completed the DCT during clinical evaluation. Seventy-four percent (N = 57) were classified as valid and 26% as noncredible (N = 20) via the Word Memory Test (WMT) and Test of Memory Malingering (TOMM)...
June 28, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28639802/a-cross-cultural-analysis-of-the-test-of-memory-malingering-among-latin-american-spanish-speaking-adults
#16
Alicia Nijdam-Jones, Diego Rivera, Barry Rosenfeld, Juan Carlos Arango-Lasprilla
Cognitive efforts tests, such as the Test of Memory Malingering (TOMM; Tombaugh, 1997), are widely used internationally, yet there is a dearth of research that has assessed the utility of these measures in different cultures, countries, and languages. This study evaluated the specificity of the TOMM Trial 2 among a sample of 3,590 Spanish-speaking adults residing in 8 Latin American countries (Argentina, Bolivia, Chile, Colombia, Mexico, Paraguay, Peru, and Puerto Rico). Trial 2 TOMM scores were negatively associated with participants' age and positively associated with level of education...
June 22, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/28632024/performance-validity-testing-in-a-clinical-sample-of-adults-with-sickle-cell-disease
#17
Katherine E Dorociak, Evan T Schulze, Lauren E Piper, Robert E Molokie, Julie K Janecek
OBJECTIVE: Neuropsychologists utilize performance validity tests (PVTs) as objective means for drawing inferences about performance validity. The Test of Memory Malingering (TOMM) is a well-validated, stand-alone PVT and the Reliable Digit Span (RDS) and Reliable Digit Span-Revised (RDS-R) from the Digit Span subtest of the WAIS-IV are commonly employed, embedded PVTs. While research has demonstrated the utility of these PVTs with various clinical samples, no research has investigated their use in adults with sickle cell disease (SCD), a condition associated with multiple neurological, physical, and psychiatric symptoms...
June 15, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28624828/unique-imaging-features-enabling-the-prenatal-diagnosis-of-developmental-venous-anomalies-a-persistent-echogenic-brain-lesion-drained-by-a-collecting-vein-in-contrast-with-normal-brain-parenchyma-on-mri
#18
Karina Krajden Haratz, Alon Peled, Boris Weizman, Liat Gindes, Mordechai Tamarkin, Dorit Lev, Dvora Kidron, Liat Ben-Sira, Gustavo Malinger, Tally Lerman-Sagie, Zvi Leibovitz
OBJECTIVE: To describe the prenatal imaging features enabling diagnosis of developmental venous anomalies (DVA). METHODS: Four fetuses with unexplained persistent echogenic parenchymal brain lesions were studied. The evaluation included dedicated neurosonography, fetal MRI, serology for intrauterine infection, screening for coagulation abnormalities, and chromosomal microarray. Postnatal neurodevelopmental follow-up or autopsy results were assessed. RESULTS: DVA presented as very slowly growing echogenic brain lesions without cystic components, calcifications, or structural changes on otherwise normal neurosonographic scans performed at 2- to 3-week intervals...
June 17, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28622821/the-therapeutic-discharge-an-approach-to-dealing-with-deceptive-patients
#19
John B Taylor, Scott R Beach, Nicholas Kontos
OBJECTIVE: Patients with factitious disorder or malingering behaviors pose particular problems in acute care settings. We sought to describe a manner to effectively discharge these patients and keep further harm, iatrogenic or otherwise, from being inflicted. METHOD: Once an indication has been identified, the therapeutic discharge can be carried out in a stepwise fashion, resulting in a safe discharge. We outlined how to prepare for, and execute, the therapeutic discharge, along with preemptive consideration of complications that may arise...
May 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28617092/determination-of-the-smoking-gun-of-intent-significance-testing-of-forced-choice-results-in-social-security-claimants
#20
Laurence M Binder, Michael D Chafetz
OBJECTIVE: Significantly below-chance findings on forced choice tests have been described as revealing "the smoking gun of intent" that proved malingering. The issues of probability levels, one-tailed vs. two-tailed tests, and the combining of PVT scores on significantly below-chance findings were addressed in a previous study, with a recommendation of a probability level of .20 to test the significance of below-chance results. The purpose of the present study was to determine the rate of below-chance findings in a Social Security Disability claimant sample using the previous recommendations...
June 15, 2017: Clinical Neuropsychologist
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