keyword
https://read.qxmd.com/read/37945356/ketogenic-diet-and-the-skin
#21
REVIEW
Dana Harb, Lina Abdullah, Mazen Kurban, Ossama Abbas
In dermatology, the role of dietary modifications as a means to manage or prevent skin disorders has recently gained special attention among patients and physicians. This is especially true for the currently popular ketogenic diet (KD), which comprises low carbohydrate, high fat, and adequate amount of protein. Recent evidence from basic science research, small clinical trials, population studies, and reports has presented promising potential role of KD as a supplementary or adjuvant treatment in different cutaneous disorders mainly due to its anti-inflammatory properties...
2023: Skinmed
https://read.qxmd.com/read/37933032/identification-of-biomarkers-of-acne-based-on-transcriptome-analysis-and-combined-with-network-pharmacology-to-explore-the-therapeutic-mechanism-of-jinhuang-ointment
#22
JOURNAL ARTICLE
Minghui Li, Xue Gao, Tianai Miao, Hongfeng Sun
The incidence of acne is on the rise due to unhealthy diet and living habits. Jinhuang ointment (JHO) is a classic prescription composed of 10 kinds of commonly used Chinese herbal medicine, which has been widely used in clinical prevention and treatment of skin inflammatory diseases since ancient times. However, the pharmacological mechanism and target of JHO are not clear. The acne microarray dataset was downloaded from gene expression omnibus database to identify differentially expressed genes (DEG). Immune infiltration was analyzed by CiberSort algorithm...
November 3, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/37899421/dietary-factors-and-hidradenitis-suppurativa
#23
REVIEW
Alan S Shen, Jessica S Johnson, Michelle Lynn Kerns
Hidradenitis suppurativa (HS) is a debilitating chronic inflammatory skin condition affecting hair follicles in flexural sites. Obesity is considered to be a risk factor for HS occurrence and thought to be associated with increased severity of HS symptoms. Here, we review the literature examining the impact of dietary factors on HS. Moreover, we propose potential mechanistic links between dietary factors and HS pathogenesis, incorporating evidence from both clinical and basic science studies.
October 30, 2023: Dermatology and Therapy
https://read.qxmd.com/read/37894066/ameliorative-effects-of-anthocyanin-metabolites-on-western-diet-induced-nafld-by-modulating-co-occurrence-networks-of-gut-microbiome
#24
JOURNAL ARTICLE
Hironobu Nakano, Kozue Sakao, Koji Wada, De-Xing Hou
Anthocyanins (Acn) have been reported to have preventive effects on Western diet (WD)-induced non-alcoholic fatty liver disease (NAFLD). However, the amount of Acn that reached the bloodstream were less than 1%, suggesting that anthocyanin metabolites (Acn-M) in the gut may contribute to their in vivo effects. This study is focused on a gut microbiota investigation to elucidate the effect of two major Acn-M, protocatechuic acid (PC) and phloroglucinol carboxaldehyde (PG), on NAFLD prevention. C57BL/6N male mice were divided into five groups and fed with a normal diet (ND), WD, WD + 0...
September 27, 2023: Microorganisms
https://read.qxmd.com/read/37892480/dietary-patterns-in-acne-and-rosacea-patients-a-controlled-study-and-comprehensive-analysis
#25
JOURNAL ARTICLE
Anne Guertler, Arina Volsky, Quirine Eijkenboom, Tobias Fiedler, Lars E French, Markus Reinholz
As the relationship between exposome factors and inflammatory skin diseases is gaining increasing attention, the objective of this study was to investigate dietary patterns among acne and rosacea patients and to establish the disease risk attributable to nutrition. In this cross-sectional, controlled study, patients' dietary habits were assessed via subjective ratings of beneficial and trigger foods, followed by standardized food frequency surveys (FFS). Scores for disease-specific risk stratification based on dietary habits were proposed...
October 17, 2023: Nutrients
https://read.qxmd.com/read/37884260/popular-diets-and-skin-effects-a-narrative-review
#26
REVIEW
M Mansilla-Polo, J Piquero-Casals, D Morgado-Carrasco
Numerous diets for losing weight, building strength, and managing a range of cardiovascular, neurologic, and skin diseases have become popular in recent years. The ketogenic diet and intermittent fasting in particular have shown promising results in clinical and sports medicine. The Mediterranean diet, in turn, is widely recognized for its numerous health benefits. Also popular are the paleo diet and vegan and gluten-free diets. Positive effects on inflammatory conditions, such as psoriasis, atopic dermatitis, hidradenitis suppurativa, and acne, have been observed in patients who practice intermittent fasting or follow ketogenic or Mediterranean diets...
October 25, 2023: Actas Dermo-sifiliográficas
https://read.qxmd.com/read/37880791/the-effects-of-intermittent-fasting-diet-alone-or-in-combination-with-probiotic-supplementation-in-comparison-with-calorie-restricted-diet-on-metabolic-and-hormonal-profile-in-patients-with-polycystic-ovary-syndrome-study-protocol-for-a-randomized-clinical
#27
JOURNAL ARTICLE
Sepide Talebi, Sakineh Shab-Bidar, Hamed Mohammadi, Ashraf Moini, Kurosh Djafarian
INTRODUCTION: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in females characterized by ovulatory dysfunction, hyperandrogenism, and other metabolic disorders. Both intermittent fasting and specific probiotics have been suggested to help improve patients with PCOS through changes in gut microbial composition, circadian clock, and metabolic regulation. Therefore, the present study aims to investigate the effects of intermittent fasting alone or in combination with probiotic supplementation compared to the calorie-restricted (CR) diet on anthropometric measures, metabolic status, inflammation, and oxidative stress in women with PCOS...
October 25, 2023: Trials
https://read.qxmd.com/read/37836436/anthocyanins-as-immunomodulatory-dietary-supplements-a-nutraceutical-perspective-and-micro-nano-strategies-for-enhanced-bioavailability
#28
REVIEW
Thadiyan Parambil Ijinu, Lorenza Francesca De Lellis, Santny Shanmugarama, Rosa Pérez-Gregorio, Parameswaran Sasikumar, Hammad Ullah, Daniele Giuseppe Buccato, Alessandro Di Minno, Alessandra Baldi, Maria Daglia
Anthocyanins (ACNs) have attracted considerable attention for their potential to modulate the immune system. Research has revealed their antioxidant and anti-inflammatory properties, which play a crucial role in immune regulation by influencing key immune cells, such as lymphocytes, macrophages, and dendritic cells. Moreover, ACNs contribute towards maintaining a balance between proinflammatory and anti-inflammatory cytokines, thus promoting immune health. Beyond their direct effects on immune cells, ACNs significantly impact gut health and the microbiota, essential factors in immune regulation...
September 26, 2023: Nutrients
https://read.qxmd.com/read/37762741/vegan-diet-in-dermatology-a-review
#29
REVIEW
Hannah Lee, Nathan Sim, Audrey Fotouhi, Steven Daveluy
Diet is known to play a role in the development of skin disorders. While a vegan diet is frequently described as a risk factor for skin disease secondary to nutritional deficiency, this risk may be overestimated. This review aims to debunk myths and provide information on skin disorders and inflammatory skin conditions that have associations with specific nutritional deficiencies in the context of a vegan diet. A literature search was performed for each nutrient and inflammatory skin disease using the PubMed/MEDLINE database and public health website pages concerning a vegan diet...
September 6, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37727660/insulin-and-the-sebaceous-gland-function
#30
REVIEW
Obumneme Emeka Okoro, Emanuela Camera, Enrica Flori, Monica Ottaviani
Insulin affects metabolic processes in different organs, including the skin. The sebaceous gland (SG) is an important appendage in the skin, which responds to insulin-mediated signals, either directly or through the insulin growth factor 1 (IGF-1) axis. Insulin cues are differently translated into the activation of metabolic processes depending on several factors, including glucose levels, receptor sensitivity, and sebocyte differentiation. The effects of diet on both the physiological function and pathological conditions of the SG have been linked to pathways activated by insulin and IGF-1...
2023: Frontiers in Physiology
https://read.qxmd.com/read/37699790/the-influence-of-dietary-patterns-on-skin-bacterial-diversity-composition-and-co-occurrence-relationships-at-forearm-and-neck-sites-of-healthy-korean-adults
#31
JOURNAL ARTICLE
Ju-Young Lee, Seayonn Kim, Dongkyu Kim, Yunhi Cho, Kun-Pyo Kim
AIMS: Diet and nutrition are important aspects of skin physiology and health. However, the influence of diet on the bacterial flora of different skin sites is not well understood. Therefore, we investigated the relationship between dietary patterns (DPs) and skin bacterial flora on the forearm (a dry site) and the neck (a sebaceous site) of healthy Korean adults. METHODS AND RESULTS: In metagenomics analysis, Shannon and Simpson indices were higher on the forearm than on the neck and were negatively correlated with the two dominant species, Cutibacterium acnes and Staphylococcus epidermidis, on two skin sites...
September 5, 2023: Journal of Applied Microbiology
https://read.qxmd.com/read/37686829/targeting-metabolic-syndrome-in-hidradenitis-suppurativa-by-phytochemicals-as-a-potential-complementary-therapeutic-strategy
#32
REVIEW
Katrin Witte, Kerstin Wolk, Ellen Witte-Händel, Torben Krause, Georgios Kokolakis, Robert Sabat
Hidradenitis suppurativa (HS) is a chronic inflammatory disease characterized by the appearance of painful inflamed nodules, abscesses, and pus-draining sinus tracts in the intertriginous skin of the groins, buttocks, and perianal and axillary regions. Despite its high prevalence of ~0.4-1%, therapeutic options for HS are still limited. Over the past 10 years, it has become clear that HS is a systemic disease, associated with various comorbidities, including metabolic syndrome (MetS) and its sequelae. Accordingly, the life expectancy of HS patients is significantly reduced...
August 30, 2023: Nutrients
https://read.qxmd.com/read/37665965/red-faced-lies-a-qualitative-analysis-of-online-misinformation-and-conspiracy-theories-in-rosacea
#33
JOURNAL ARTICLE
James Fuller, Michelle Murphy, Cathal O'Connor
Rosacea is a common chronic inflammatory skin disease with a complex etiology and major psychological impact, rendering patients susceptible to misinformation. We aimed to assess the content of rosacea-related misinformation online. A formal review of PubMed was performed, using the terms 'rosacea' AND 'misinformation' OR 'disinformation' OR 'conspiracy theory', along with informal Google searches using combinations of these terms, and further targeted searches on Twitter, Facebook, Instagram, and TikTok. Key areas of misinformation identified in the search included mislabelling as adult acne; falsehoods about rosacea only occurring in older adults or in individuals with lightly pigmented skin; incorrect causes such as make-up or diet; and misleading 'cures', some of which may lead to exacerbation of the underlying rosacea...
September 4, 2023: Clinical and Experimental Dermatology
https://read.qxmd.com/read/37600837/efficacy-of-soy-protein-concentrate-replacing-animal-protein-supplements-in-mucosa-associated-microbiota-intestinal-health-and-growth-performance-of-nursery-pigs
#34
JOURNAL ARTICLE
Zixiao Deng, Marcos Elias Duarte, Sung Woo Kim
This study investigated the effects of using soy protein concentrate (SPC) to replace animal protein supplements on mucosa-associated microbiota, intestinal health, and growth performance of nursery pigs. Fifty-six newly weaned pigs (BW = 6.4 ± 0.6 kg) were allotted to 5 treatments in a randomized complete block design. Pigs were fed for 35 d in 3 phases (P; 1, 2, 3) for 10, 12, 13 d, respectively. Dietary treatments were: (1) basal diet with fish meal (P1: 4%, P2: 2%, and P3: 1%), poultry meal (P1: 10%, P2: 8%, and P3: 4%), and blood plasma (P1: 4%, P2: 2%, and P3: 1%), where SPC replacing none (NC); (2) basal diet with SPC replacing fish meal (RFM); (3) basal diet with SPC replacing poultry meal (RPM); (4) basal diet with SPC replacing blood plasma (RBP); and (5) basal diet with SPC replacing all animal protein supplements (PC)...
September 2023: Animal Nutrition
https://read.qxmd.com/read/37571253/linoleic-acid-induced-changes-in-sz95-sebocytes-comparison-with-palmitic-acid-and-arachidonic-acid
#35
JOURNAL ARTICLE
Dóra Kovács, Emanuela Camera, Szilárd Póliska, Alessia Cavallo, Miriam Maiellaro, Katalin Dull, Florian Gruber, Christos C Zouboulis, Andrea Szegedi, Dániel Törőcsik
Linoleic acid (LA) is an essential omega-6 polyunsaturated fatty acid (PUFA) derived from the diet. Sebocytes, whose primary role is to moisturise the skin, process free fatty acids (FFAs) to produce the lipid-rich sebum. Importantly, like other sebum components such as palmitic acid (PA), LA and its derivative arachidonic acid (AA) are known to modulate sebocyte functions. Given the different roles of PA, LA and AA in skin biology, the aim of this study was to assess the specificity of sebocytes for LA and to dissect the different roles of LA and AA in regulating sebocyte functions...
July 26, 2023: Nutrients
https://read.qxmd.com/read/37502876/genomic-characterization-of-the-c-tuberculostearicum-species-complex-a-ubiquitous-member-of-the-human-skin-microbiome
#36
Nashwa M Ahmed, Payal Joglekar, Clayton Deming, Katherine P Lemon, Heidi H Kong, Julia A Segre, Sean Conlan
UNLABELLED: Corynebacterium is a predominant genus in the skin microbiome, yet its genetic diversity on skin is incompletely characterized and lacks a comprehensive set of reference genomes. Our work aims to investigate the distribution of Corynebacterium species on the skin, as well as to expand the existing genome reference catalog to enable more complete characterization of skin metagenomes. We used V1-V3 16S rRNA gene sequencing data from 14 body sites of 23 healthy volunteers to characterize Corynebacterium diversity and distribution across healthy human skin...
June 17, 2023: bioRxiv
https://read.qxmd.com/read/37484185/acne-vulgaris-and-its-association-with-dietary-habits-at-a-tertiary-care-hospital-in-karachi-pakistan
#37
JOURNAL ARTICLE
Tafazzul Hyder Zaidi, Mubashir Zafar, Bahram Khan Khoso, Rabia Ghafoor, Saba Asghar, Saima Parveen, Usaid Ahmed
BACKGROUND: Acne is a common skin disorder among younger age group. Dietary pattern are the key determinants among acne patients. The objective of this study is to determine the association of acne vulgaris with dietary habits among patients at tertiary care hospital in Karachi, Pakistan. METHODS: it is a cross sectional study and participants were selected through simple random sampling from outpatient department of tertiary care hospital in Karachi, Pakistan. Patients presenting with acne irrespective of severity and treatment were included in the study...
March 2023: Ethiopian Journal of Health Sciences
https://read.qxmd.com/read/37477901/patient-reported-burden-of-skin-disorders-in-coeliac-disease
#38
JOURNAL ARTICLE
Elli Turjanmaa, Kaisa Hervonen, Heini Huhtala, Sanna Arnala, Timo Reunala, Katri Kaukinen, Teea Salmi
OBJECTIVES: The current knowledge on the associations between coeliac disease and different skin diseases is contradictory and the patient's perspective on the burden of these is lacking. This study aimed to investigate patient-reported frequency, severity and quality of life effects of skin disorders in coeliac disease patients compared to controls and moreover to study the impacts of gluten-free diet on these skin diseases. MATERIALS AND METHODS: A study questionnaire designed for the purposes of this study and a validated Dermatology Life Quality Index (DLQI) questionnaire were posted to 600 adult members of the Finnish Coeliac Society and 1173 matched controls...
July 21, 2023: Scandinavian Journal of Gastroenterology
https://read.qxmd.com/read/37447279/influence-of-vitamin-d-on-the-incidence-of-metabolic-syndrome-and-hormonal-balance-in-patients-with-polycystic-ovary-syndrome
#39
JOURNAL ARTICLE
Katarzyna Lejman-Larysz, Anna Golara, Marta Baranowska, Mateusz Kozłowski, Paweł Guzik, Iwona Szydłowska, Jolanta Nawrocka-Rutkowska, Elżbieta Sowińska-Przepiera, Aneta Cymbaluk-Płoska, Agnieszka Brodowska
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder that affects 8-13% of women of reproductive age. It is one of the most common causes of infertility and is associated with hyperandrogenism in the form of hirsutism and acne, non-ovulatory cycles, and characteristic ovarian morphology. The available research on serum vitamin D deficiency in patients with PCOS and the appropriateness of vitamin D supplementation in this group of women is inconclusive, so we decided to investigate the influence of vitamin D on the incidence of metabolic syndrome and hormonal balance in patients with polycystic ovary syndrome...
June 29, 2023: Nutrients
https://read.qxmd.com/read/37447169/beneficial-effects-of-plant-based-diets-on-skin-health-and-inflammatory-skin-diseases
#40
REVIEW
Ximena Flores-Balderas, Mario Peña-Peña, Karla M Rada, Yamnia Q Alvarez-Alvarez, Carlos A Guzmán-Martín, José L Sánchez-Gloria, Fengyang Huang, Dayanara Ruiz-Ojeda, Sofía Morán-Ramos, Rashidi Springall, Fausto Sánchez-Muñoz
The human skin is a crucial organ that protects the organism from the outer environment. Skin integrity and health depend on both extrinsic and intrinsic factors. Intrinsic factors such as aging and genetic background contribute to weakened skin and disease susceptibility. Meanwhile, extrinsic factors including UV radiation, pollution, smoking, humidity, and poor diet also affect skin health and disease. On the other hand, healthy dietary patterns such as plant-based diets have gained popularity as a complementary therapy for skin health...
June 22, 2023: Nutrients
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